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Leukemia

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Articles published in Leukemia
Retrieve available abstracts of 331 articles:
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February 2012

MI JQ , Wang X, Yao Y, Lu HJ, et al
Newly diagnosed acute lymphoblastic leukemia in China (II): Prognosis related to genetic abnormalities in a series of 1 091 cases.
Leukemia. 2012 Feb 2. doi: 10.1038/leu.2012.
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POSPISILOVA S , Gonzalez D, Malcikova J, Trbusek M, et al
ERIC recommendations on TP53 mutation analysis in Chronic Lymphocytic Leukemia.
Leukemia. 2012 Feb 2. doi: 10.1038/leu.2012.
PubMed Text format Related articles Abstract available

January 2012

SPYRIDONIDIS A , Labopin M, Schmid C, Volin L, et al
Outcomes and prognostic factors of adults with acute lymphoblastic leukemia who relapse after allogeneic hematopoietic cell transplantation. An analysis on behalf of the Acute Leukemia Working Party of EBMT.
Leukemia. 2012 Jan 31. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

SPIJKERS-HAGELSTEIN JA , Schneider P, Hulleman E, de Boer J, et al
Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
Leukemia. 2012 Jan 27. doi: 10.1038/leu.2011.
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ERNST T , Pflug A, Rinke J, Ernst J, et al
A somatic EZH2 mutation in a child with acute myeloid leukemia.
Leukemia. 2012 Jan 23. doi: 10.1038/leu.2012.
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CASTRO FV , McGinn OJ, Krishnan S, Marinov G, et al
5T4 oncofoetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype.
Leukemia. 2012 Jan 23. doi: 10.1038/leu.2012.
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BRAGGIO E , Kay NE, Vanwier S, Tschumper RC, et al
Longitudinal genome wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.
Leukemia. 2012 Jan 20. doi: 10.1038/leu.2012.
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KNIGHT SJ , Yau C, Clifford R, Timbs AT, et al
Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia.
Leukemia. 2012 Jan 19. doi: 10.1038/leu.2012.
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MATSUMURA T , Kami M, Yamaguchi T, Yuji K, et al
Allogeneic cord blood transplantation for adult acute lymphoblastic leukemia: retrospective survey involving 256 patients in Japan.
Leukemia. 2012 Jan 17. doi: 10.1038/leu.2012.
PubMed Text format Related articles Abstract available

WOYACH JA , Lozanski G, Ruppert AS, Lozanski A, et al
Outcome of patients with relapsed or refractory chronic lymphocytic leukemia treated with flavopiridol: impact of genetic features.
Leukemia. 2012 Jan 13. doi: 10.1038/leu.2011.
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TUNG S , Spaner DE
A role for Danazol in chronic lymphocytic leukemia.
Leukemia. 2012 Jan 13. doi: 10.1038/leu.2011.
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PORTER CC , Kim J, Fosmire S, Gearheart CM, et al
Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia.
Leukemia. 2012 Jan 13. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

RENNEVILLE A , Boissel N, Nibourel O, Berthon C, et al
Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.
Leukemia. 2012 Jan 13. doi: 10.1038/leu.2011.
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TEFFERI A , Pardanani A, Gangat N, Begna KH, et al
Leukemia risk models in primary myelofibrosis: an International Working Group study.
Leukemia. 2012 Jan 13. doi: 10.1038/leu.2011.
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O'HAYRE M , Niederst M, Fecteau JF, Nguyen VM, et al
Mechanisms and Consequences of the Loss of PHLPP1 Phosphatase in Chronic Lymphocytic Leukemia (CLL).
Leukemia. 2012 Jan 12. doi: 10.1038/leu.2012.
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PFEIFER H , Lange T, Wystub S, Wassmann B, et al
Prevalence and dynamics of bcr-abl kinase domain mutations during imatinib treatment differ in patients with newly diagnosed and recurrent bcr-abl positive acute lymphoblastic leukemia.
Leukemia. 2012 Jan 9. doi: 10.1038/leu.2012.
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HOFMANN M , Grosse-Hovest L, Nubling T, Pyz E, et al
Generation, selection and preclinical characterization of an Fc-optimized FLT3 antibody for the treatment of myeloid leukemia.
Leukemia. 2012 Jan 6. doi: 10.1038/leu.2011.
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NAKAHATA S , Saito Y, Marutsuka K, Hidaka T, et al
Clinical significance of CADM1/TSLC1/IgSF4 expression in adult T-cell leukemia/lymphoma.
Leukemia. 2012 Jan 6. doi: 10.1038/leu.2011.
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DANESHMANESH AH , Hojjat-Farsangi M, Khan AS, Jeddi-Tehrani M, et al
Monoclonal antibodies against ROR1 induce apoptosis of chronic lymphocytic leukemia (CLL) cells.
Leukemia. 2012 Jan 6. doi: 10.1038/leu.2011.
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ZUCCHETTO A , Vaisitti T, Benedetti D, Tissino E, et al
The CD49d/CD29 complex is physically and functionally associated with CD38 in B-cell chronic lymphocytic leukemia cells.
Leukemia. 2012 Jan 6. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

December 2011

SHEDDEN K , Li Y, Ouillette P, Malek SN, et al
Characteristics of chronic lymphocytic leukemia with somatically acquired mutations in NOTCH1 exon 34.
Leukemia. 2011 Dec 20. doi: 10.1038/leu.2011.
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CONGLETON J , Macdonald R, Yen A
Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK dependent differentiation of myeloid leukemia cells.
Leukemia. 2011 Dec 19. doi: 10.1038/leu.2011.
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SPECTOR MS , Iossifov I, Kritharis A, He C, et al
Mast-cell leukemia exome sequencing reveals a mutation in the IgE mast-cell receptor beta chain and KIT V654A.
Leukemia. 2011 Dec 16. doi: 10.1038/leu.2011.
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LODER S , Fakler M, Schoeneberger H, Cristofanon S, et al
RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis.
Leukemia. 2011 Dec 16. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

NORDLUND J , Kiialainen A, Karlberg O, Berglund EC, et al
Digital gene expression profiling of primary acute lymphoblastic leukemia cells.
Leukemia. 2011 Dec 16. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

LUIS TC , Ichii M, Brugman MH, Kincade P, et al
Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development.
Leukemia. 2011 Dec 15. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

TSUBOI A , Oka Y, Kyo T, Katayama Y, et al
Long-term WT1 peptide vaccination for patients with acute myeloid leukemia with minimal residual disease.
Leukemia. 2011 Dec 13. doi: 10.1038/leu.2011.
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LIU P , Xu B, Shen W, Zhu H, et al
Dysregulation of TNFalpha-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1.
Leukemia. 2011 Dec 13. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

GILES FJ , Kantarjian HM, le Coutre PD, Baccarani M, et al
Nilotinib is effective in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blastic phase.
Leukemia. 2011 Dec 13. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

ISHIYAMA K , Takami A, Kanda Y, Nakao S, et al
Prognostic factors for acute myeloid leukemia patients with t(6;9)(p23;q34) who underwent an allogeneic hematopoietic stem cell transplant.
Leukemia. 2011 Dec 9. doi: 10.1038/leu.2011.
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JANSSEN JJ , Deenik W, Smolders KG, van Kuijk BJ, et al
Residual normal stem cells can be detected in newly diagnosed chronic myeloid leukemia patients by a new flow cytometric approach and predict for optimal response to imatinib.
Leukemia. 2011 Dec 9. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

AGIRRE X , Martinez-Climent JA, Odero MD, Prosper F, et al
Epigenetic regulation of miRNA genes in acute leukemia.
Leukemia. 2011 Dec 6. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

WILLEMS L , Chapuis N, Puissant A, Maciel TT, et al
The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.
Leukemia. 2011 Dec 6. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

MIEDEMA KG , Tissing WJ, Te Poele EM, Kamps WA, et al
Polymorphisms in the TLR6 gene associated with the inverse association between childhood acute lymphoblastic leukemia and atopic disease.
Leukemia. 2011 Dec 2. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

BELLONI E , Shing D, Tapinassi C, Viale A, et al
In vivo expression of an aberrant MYB-GATA1 fusion induces leukemia in the presence of GATA1 reduced levels.
Leukemia. 2011;25:1922.
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DE JONGE HJ , Woolthuis CM, Vos AZ, Mulder A, et al
Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML.
Leukemia. 2011;25:1825-33.
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ENOMOTO Y , Kitaura J, Hatakeyama K, Watanuki J, et al
Emu/miR-125b transgenic mice develop lethal B-cell malignancies.
Leukemia. 2011;25:1849-56.
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KOHLMANN A , Klein HU, Weissmann S, Bresolin S, et al
The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.
Leukemia. 2011;25:1840-8.
PubMed Text format Related articles Abstract available

November 2011

METZELER KH , Walker A, Geyer S, Garzon R, et al
DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia.
Leukemia. 2011 Nov 29. doi: 10.1038/leu.2011.
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ESTEY EH
How to manage high-risk acute myeloid leukemia.
Leukemia. 2011 Nov 25. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

WEISSMANN S , Alpermann T, Grossmann V, Kowarsch A, et al
Landscape of TET2 mutations in acute myeloid leukemia.
Leukemia. 2011 Nov 25. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

WIKTOR-JEDRZEJCZAK W , Dearden C, de Wreede L, van Biezen A, et al
Hematopoietic stem cell transplantation in T-prolymphocytic leukemia: a retrospective study from the European Group for Blood and Marrow Transplantation and the Royal Marsden Consortium.
Leukemia. 2011 Nov 25. doi: 10.1038/leu.2011.
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DE BOCK CE , Ardjmand A, Molloy TJ, Bone SM, et al
The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia.
Leukemia. 2011 Nov 25. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

FUKA G , Kantner HP, Grausenburger R, Inthal A, et al
Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts.
Leukemia. 2011 Nov 18. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

HOMMINGA I , Pieters R, Meijerink JP
NKL homeobox genes in leukemia.
Leukemia. 2011 Nov 18. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

LILLJEBJORN H , Rissler M, Lassen C, Heldrup J, et al
Whole-exome sequencing of pediatric acute lymphoblastic leukemia.
Leukemia. 2011 Nov 18. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

LE COUTRE PD , Giles FJ, Hochhaus A, Apperley JF, et al
Nilotinib in patients with Ph+ chronic myeloid leukemia in accelerated phase following imatinib resistance or intolerance: 24-month follow-up results.
Leukemia. 2011 Nov 11. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

ELLINGHAUS E , Stanulla M, Richter G, Ellinghaus D, et al
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
Leukemia. 2011 Nov 11. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

SPANER DE
Oral high-dose glucocorticoids and Ofatumumab in fludarabine-resistant Chronic Lymphocytic Leukemia.
Leukemia. 2011 Nov 8. doi: 10.1038/leu.2011.
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KONOPLEVA M , Milella M, Ruvolo P, Watts JC, et al
MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.
Leukemia. 2011 Nov 8. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

BUECHELE C , Baessler T, Wirths S, Schmohl JU, et al
Glucocorticoid-induced TNFR-related protein (GITR) ligand modulates cytokine release and NK cell reactivity in chronic lymphocytic leukemia (CLL).
Leukemia. 2011 Nov 8. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

MCCORMACK E , Haaland I, Venas G, Forthun RB, et al
Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.
Leukemia. 2011 Nov 8. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

DUNNE J , Mannari D, Farzaneh T, Gessner A, et al
AML1/ETO and POU4F1 synergy drives B-lymphoid gene expression typical of t(8;21) acute myeloid leukemia.
Leukemia. 2011 Nov 8. doi: 10.1038/leu.2011.
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MAHINDRA A , Kalaycio ME, Vela-Ojeda J, Vesole DH, et al
Hematopoietic cell transplantation for primary plasma cell leukemia: results from the Center for International Blood and Marrow Transplant Research.
Leukemia. 2011 Nov 1. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

SCIELZO C , Apollonio B, Scarfo L, Janus A, et al
The functional in vitro response to CD40 ligation reflects a different clinical outcome in patients with chronic lymphocytic leukemia.
Leukemia. 2011;25:1794.
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HART S , Goh KC, Novotny-Diermayr V, Hu CY, et al
SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies.
Leukemia. 2011;25:1751-9.
PubMed Text format Related articles Abstract available

MAR BG , Amakye D, Aifantis I, Buonamici S, et al
The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.
Leukemia. 2011;25:1665-73.
PubMed Text format Related articles Abstract available

DAMM F , Thol F, Hollink I, Zimmermann M, et al
Prevalence and prognostic value of IDH1 and IDH2 mutations in childhood AML: a study of the AML-BFM and DCOG study groups.
Leukemia. 2011;25:1704-10.
PubMed Text format Related articles Abstract available

October 2011

POLLYEA DA , Kohrt HE, Gallegos L, Figueroa ME, et al
Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia.
Leukemia. 2011 Oct 28. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

STUMPEL DJ , Schneider P, Seslija L, Osaki H, et al
Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia.
Leukemia. 2011 Oct 21. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

LARANJEIRA AB , de Vasconcellos JF, Sodek L, Spago MC, et al
IGFBP7 participates in the reciprocal interaction between acute lymphoblastic leukemia and BM stromal cells and in leukemia resistance to asparaginase.
Leukemia. 2011 Oct 18. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

SCHMIEGELOW K , Lausten Thomsen U, Baruchel A, Pacheco CE, et al
High concordance of subtypes of childhood acute lymphoblastic leukemia within families: lessons from sibships with multiple cases of leukemia.
Leukemia. 2011 Oct 18. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

SCHERMAN E , Malak S, Perot C, Gorin NC, et al
Interest of the association azacitidine-lenalidomide as frontline therapy in high-risk myelodysplasia or acute myeloid leukemia with complex karyotype.
Leukemia. 2011 Oct 14. doi: 10.1038/leu.2011.
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WOOLTHUIS CM , Han L, Verkaik-Schakel RN, van Gosliga D, et al
Downregulation of MEIS1 impairs long-term expansion of CD34(+) NPM1-mutated acute myeloid leukemia cells.
Leukemia. 2011 Oct 11. doi: 10.1038/leu.2011.
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GEORGIOU G , Efthymiou A, Vardounioti I, Boutsikas G, et al
Development of acute myeloid leukemia with NPM1 mutation, in Ph-negative clone, during treatment of CML with imatinib.
Leukemia. 2011 Oct 11. doi: 10.1038/leu.2011.
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CHAIB H , Nebbioso A, Prebet T, Castellano R, et al
Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1.
Leukemia. 2011 Oct 7. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

KOFLER DM , Gawlik BB, Elter T, Gianella-Borradori A, et al
Phase 1b trial of atacicept, a recombinant protein binding BLyS and APRIL, in patients with chronic lymphocytic leukemia.
Leukemia. 2011 Oct 7. doi: 10.1038/leu.2011.
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LV M , Zhang X, Jia H, Li D, et al
An oncogenic role of miR-142-3p in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-alpha and cAMP/PKA pathways.
Leukemia. 2011 Oct 7. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

GRIMALDI C , Chiarini F, Tabellini G, Ricci F, et al
AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications.
Leukemia. 2011 Oct 4. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

KREUTZMAN A , Ladell K, Koechel C, Gostick E, et al
Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation.
Leukemia. 2011;25:1587-97.
PubMed Text format Related articles Abstract available

SULIS ML , Saftig P, Ferrando AA
Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL.
Leukemia. 2011;25:1564-9.
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September 2011

TYNER JW , Jemal AM, Thayer M, Druker BJ, et al
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
Leukemia. 2011 Sep 30. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

CICCONE M , Agostinelli C, Rigolin GM, Piccaluga PP, et al
Proliferation centers in chronic lymphocytic leukemia: correlation with cytogenetic and clinicobiological features in consecutive patients analyzed on tissue microarrays.
Leukemia. 2011 Sep 23. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

FRANKE NE , Niewerth D, Assaraf YG, van Meerloo J, et al
Impaired bortezomib binding to mutant beta5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells.
Leukemia. 2011 Sep 23. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

VICENTE C , Vazquez I, Conchillo A, Garcia-Sanchez MA, et al
Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities.
Leukemia. 2011 Sep 9. doi: 10.1038/leu.2011.
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CHEN CI , Koschmieder S, Kerstiens L, Schemionek M, et al
NK cells are dysfunctional in human chronic myelogenous leukemia before and on imatinib treatment and in BCR-ABL-positive mice.
Leukemia. 2011 Sep 9. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

LENGFELDER E , Hofmann WK, Nowak D
Impact of arsenic trioxide in the treatment of acute promyelocytic leukemia.
Leukemia. 2011 Sep 9. doi: 10.1038/leu.2011.
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TSYKUNOVA G , Reikvam H, Hovland R, Bruserud O, et al
The surface molecule signature of primary human acute myeloid leukemia (AML) cells is highly associated with NPM1 mutation status.
Leukemia. 2011 Sep 9. doi: 10.1038/leu.2011.
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KRAUSE G , Patz M, Isaeva P, Wigger M, et al
Action of novel CD37 antibodies on chronic lymphocytic leukemia cells.
Leukemia. 2011 Sep 2. doi: 10.1038/leu.2011.
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LANASA MC , Allgood SD, Slager SL, Dave SS, et al
Immunophenotypic and gene expression analysis of monoclonal B-cell lymphocytosis shows biologic characteristics associated with good prognosis CLL.
Leukemia. 2011;25:1459-66.
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HOFBAUER JP , Heyder C, Denk U, Kocher T, et al
Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Leukemia. 2011;25:1452-8.
PubMed Text format Related articles Abstract available

August 2011

BHOJWANI D , Pei D, Sandlund JT, Jeha S, et al
ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy.
Leukemia. 2011 Aug 26. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

TERWEY TH , Vega-Ruiz A, Hemmati PG, Martus P, et al
NIH-defined graft-versus-host disease after reduced intensity or myeloablative conditioning in patients with acute myeloid leukemia.
Leukemia. 2011 Aug 26. doi: 10.1038/leu.2011.
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DOS SANTOS GA , Abreu E Lima RS, Pestana CR, Lima AS, et al
(+)alpha-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.
Leukemia. 2011 Aug 26. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

GALE RP , Opelz G
Commentary: does immune suppression increase risk of developing acute myeloid leukemia?
Leukemia. 2011 Aug 26. doi: 10.1038/leu.2011.
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DE VRIES JF , Zwaan CM, De Bie M, Voerman JS, et al
The novel calicheamicin-conjugated CD22 antibody inotuzumab ozogamicin (CMC-544) effectively kills primary pediatric acute lymphoblastic leukemia cells.
Leukemia. 2011 Aug 26. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

ISHIYAMA K , Takami A, Kanda Y, Nakao S, et al
Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia with t(6;9)(p23;q34) dramatically improves the patient prognosis: a matched-pair analysis.
Leukemia. 2011 Aug 26. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

STEVANOVIC S , Griffioen M, Nijmeijer BA, van Schie ML, et al
Human allo-reactive CD4+ T cells as strong mediators of anti-tumor immunity in NOD/scid mice engrafted with human acute lymphoblastic leukemia.
Leukemia. 2011 Aug 23. doi: 10.1038/leu.2011.
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DIAMANTI P , Cox CV, Blair A
Comparison of childhood leukemia initiating cell populations in NOD/SCID and NSG mice.
Leukemia. 2011 Aug 23. doi: 10.1038/leu.2011.
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FERRETTI E , Montagna D, Di Carlo E, Cocco C, et al
Absence of IL-12Rbeta2 in CD33(+)CD38(+) pediatric acute myeloid leukemia cells favours progression in NOD/SCID/IL2RgammaC-deficient mice.
Leukemia. 2011 Aug 16. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

MARIN D , Gabriel IH, Ahmad S, Foroni L, et al
KIR2DS1 genotype predicts for complete cytogenetic response and survival in newly diagnosed chronic myeloid leukemia patients treated with imatinib.
Leukemia. 2011 Aug 16. doi: 10.1038/leu.2011.
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CHOU WC , Peng KY, Lei WC, Ko BS, et al
Persistence of mutant isocitrate dehydrogenase in patients with acute myeloid leukemia in remission.
Leukemia. 2011 Aug 16. doi: 10.1038/leu.2011.
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SHAMI PJ , Deininger M
Evolving treatment strategies for patients newly diagnosed with chronic myeloid leukemia: the role of second-generation BCR-ABL inhibitors as first-line therapy.
Leukemia. 2011 Aug 16. doi: 10.1038/leu.2011.
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NEGROTTO S , Ng KP, Jankowska AM, Bodo J, et al
CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors.
Leukemia. 2011 Aug 12. doi: 10.1038/leu.2011.
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KRASZEWSKA MD , Dawidowska M, Larmonie NS, Kosmalska M, et al
DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL.
Leukemia. 2011 Aug 12. doi: 10.1038/leu.2011.
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LIU J , Xing H, Chen Y, Wang L, et al
PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.
Leukemia. 2011 Aug 12. doi: 10.1038/leu.2011.
PubMed Text format Related articles Abstract available

DAMM F , Bunke T, Thol F, Markus B, et al
Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia.
Leukemia. 2011 Aug 9. doi: 10.1038/leu.2011.
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METZGEROTH G , Erben P, Martin H, Mousset S, et al
Limited clinical activity of nilotinib and sorafenib in FIP1L1-PDGFRA positive chronic eosinophilic leukemia with imatinib-resistant T674I mutation.
Leukemia. 2011 Aug 5. doi: 10.1038/leu.2011.
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YUAN J , Takeuchi M, Negishi M, Oguro H, et al
Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells.
Leukemia. 2011;25:1335-43.
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BACHER U , Kern W, Alpermann T, Schnittger S, et al
Prognosis in patients with MDS or AML and bone marrow blasts between 10% and 30% is not associated with blast counts but depends on cytogenetic and molecular genetic characteristics.
Leukemia. 2011;25:1361-4.
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PAULSSON K , Lindgren D, Johansson B
SNP array analysis of leukemic relapse samples after allogeneic hematopoietic stem cell transplantation with a sibling donor identifies meiotic recombination spots and reveals possible correlation with the breakpoints of acquired genetic aberrations.
Leukemia. 2011;25:1358-61.
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July 2011

HOEGH-PETERSEN M , Sy S, Ugarte-Torres A, Williamson TS, et al
High Epstein-Barr virus-specific T-cell counts are associated with near-zero likelihood of acute myeloid leukemia relapse after hematopoietic cell transplantation.
Leukemia. 2011 Jul 29. doi: 10.1038/leu.2011.
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AVET-LOISEAU H , Roussel M, Campion L, Leleu X, et al
Cytogenetic and therapeutic characterization of primary plasma cell leukemia: the IFM experience.
Leukemia. 2011 Jul 29. doi: 10.1038/leu.2011.
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SI J , Mueller L, Collins SJ
GSK3 inhibitors enhance retinoic acid receptor activity and induce the differentiation of retinoic acid-sensitive myeloid leukemia cells.
Leukemia. 2011 Jul 26. doi: 10.1038/leu.2011.
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IBBOTSON R , Athanasiadou A, Sutton LA, Davis Z, et al
Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant.
Leukemia. 2011 Jul 26. doi: 10.1038/leu.2011.
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LICHTMAN MA
Obesity and the risk of chronic myelogenous leukemia: is this another example of the neoplastic effects of increased body fat?
Leukemia. 2011 Jul 22. doi: 10.1038/leu.2011.
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RENNEVILLE A , Boissel N, Helevaut N, Nibourel O, et al
Wilms' tumor 1 single-nucleotide polymorphism rs16754 does not predict clinical outcome in adult acute myeloid leukemia.
Leukemia. 2011 Jul 15. doi: 10.1038/leu.2011.
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LANCET JE , Ravandi F, Ricklis RM, Cripe LD, et al
A phase Ib study of vosaroxin, an anticancer quinolone derivative, in patients with relapsed or refractory acute leukemia.
Leukemia. 2011 Jul 15. doi: 10.1038/leu.2011.
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WIETEN E , van der Linden-Schrever BE, Sonneveld E, Veerman AJ, et al
CD73 (5'-nucleotidase) expression has no prognostic value in children with acute lymphoblastic leukemia.
Leukemia. 2011 Jul 15. doi: 10.1038/leu.2011.
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WEISBERG E , Ray A, Barrett R, Nelson E, et al
Smac mimetics: implications for enhancement of targeted therapies in leukemia.
Leukemia. 2011;25:1221.
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TEFFERI A
Mutations galore in myeloproliferative neoplasms: would the real Spartacus please stand up?
Leukemia. 2011;25:1059-63.
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STEGELMANN F , Bullinger L, Schlenk RF, Paschka P, et al
DNMT3A mutations in myeloproliferative neoplasms.
Leukemia. 2011;25:1217-9.
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ITZYKSON R , Kosmider O, Cluzeau T, Mansat-De Mas V, et al
Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias.
Leukemia. 2011;25:1147-52.
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OSTERGAARD M , Nyvold CG, Jovanovic JV, Andersen MT, et al
Development of standardized approaches to reporting of minimal residual disease data using a reporting software package designed within the European LeukemiaNet.
Leukemia. 2011;25:1168-73.
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PELLICANO F , Simara P, Sinclair A, Helgason GV, et al
The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells.
Leukemia. 2011;25:1159-67.
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BURNETT AK , Hills RK, Hunter A, Milligan D, et al
The addition of arsenic trioxide to low-dose Ara-C in older patients with AML does not improve outcome.
Leukemia. 2011;25:1122-7.
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OTTO N , Manukjan G, Gohring G, Hofmann W, et al
ICSBP promoter methylation in myelodysplastic syndromes and acute myeloid leukaemia.
Leukemia. 2011;25:1202-7.
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STELLJES M , Corbacioglu A, Schlenk RF, Dohner K, et al
Allogeneic stem cell transplant to eliminate germline mutations in the gene for CCAAT-enhancer-binding protein alpha from hematopoietic cells in a family with AML.
Leukemia. 2011;25:1209-10.
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WALTER MJ , Ding L, Shen D, Shao J, et al
Recurrent DNMT3A mutations in patients with myelodysplastic syndromes.
Leukemia. 2011;25:1153-8.
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June 2011

NG KP , Ebrahem Q, Negrotto S, Mahfouz RZ, et al
p53 Independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.
Leukemia. 2011 Jun 24. doi: 10.1038/leu.2011.
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ZHANG X , Reis M, Khoriaty R, Li Y, et al
Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia.
Leukemia. 2011 Jun 24. doi: 10.1038/leu.2011.
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TIBALDI E , Brunati AM, Zonta F, Frezzato F, et al
Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells.
Leukemia. 2011 Jun 24. doi: 10.1038/leu.2011.
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CANALE S , Cocco C, Frasson C, Seganfreddo E, et al
Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model.
Leukemia. 2011 Jun 24. doi: 10.1038/leu.2011.
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SCHOTTE D , Pieters R, Den Boer ML
MicroRNAs in acute leukemia: from biological players to clinical contributors.
Leukemia. 2011 Jun 24. doi: 10.1038/leu.2011.
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LUCK SC , Russ AC, Botzenhardt U, Paschka P, et al
Deregulated apoptosis signaling in core-binding factor leukemia differentiates clinically relevant, molecular marker-independent subgroups.
Leukemia. 2011 Jun 24. doi: 10.1038/leu.2011.
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OBRO NF , Marquart HV, Madsen HO, Ryder LP, et al
Immunophenotype-defined sub-populations are common at diagnosis in childhood B-cell precursor acute lymphoblastic leukemia.
Leukemia. 2011 Jun 17. doi: 10.1038/leu.2011.
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DESHPANDE AJ , Rouhi A, Lin Y, Stadler C, et al
The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice.
Leukemia. 2011 Jun 17. doi: 10.1038/leu.2011.
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RUVOLO PP , Qui YH, Coombes KR, Zhang N, et al
Low expression of PP2A regulatory subunit B55alpha is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients.
Leukemia. 2011 Jun 10. doi: 10.1038/leu.2011.
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AMREIN L , Rachid Z, Jean-Claude B, Soulieres D, et al
ZRF4, a combi-molecule with increased efficacy as compared with the individual components in chronic lymphocytic leukemia lymphocytes in vitro.
Leukemia. 2011.
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MALAISE M , Neumeier M, Botteron C, Dohner K, et al
Stable and reproducible engraftment of primary adult and pediatric acute myeloid leukemia in NSG mice.
Leukemia. 2011.
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RIJNEVELD AW , van der Holt B, Daenen SM, Biemond BJ, et al
Intensified chemotherapy inspired by a pediatric regimen combined with allogeneic transplantation in adult patients with acute lymphoblastic leukemia up to the age of 40.
Leukemia. 2011.
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DESPEAUX M , Labat E, Gadelorge M, Prade N, et al
Critical features of FAK-expressing AML bone marrow microenvironment through leukemia stem cell hijacking of mesenchymal stromal cells.
Leukemia. 2011.
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ANDERSSON AK , Miller DW, Lynch JA, Lemoff AS, et al
IDH1 and IDH2 mutations in pediatric acute leukemia.
Leukemia. 2011.
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CARDOSO BA , de Almeida SF, Laranjeira AB, Carmo-Fonseca M, et al
TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells.
Leukemia. 2011.
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LOUDIN MG , Wang J, Eastwood Leung HC, Gurusiddappa S, et al
Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles.
Leukemia. 2011.
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ROCHE-LESTIENNE C , Marceau A, Labis E, Nibourel O, et al
Mutation analysis of TET2, IDH1, IDH2 and ASXL1 in chronic myeloid leukemia.
Leukemia. 2011.
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ICHIM CV , Atkins HL, Iscove NN, Wells RA, et al
Identification of a role for the nuclear receptor EAR-2 in the maintenance of clonogenic status within the leukemia cell hierarchy.
Leukemia. 2011.
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ALLAN EK , Holyoake TL, Craig AR, Jorgensen HG, et al
Omacetaxine may have a role in chronic myeloid leukaemia eradication through downregulation of Mcl-1 and induction of apoptosis in stem/progenitor cells.
Leukemia. 2011;25:985-94.
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LANGERAK AW , Davi F, Ghia P, Hadzidimitriou A, et al
Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases.
Leukemia. 2011;25:979-84.
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HUSSEIN K , Horny HP, Busche G, Gorner M, et al
Systemic mastocytosis (SM) with associated BCR-ABL-positive myelogenous leukaemia (SM-AHNMD): evidence that mast cells do not belong to the leukaemic clone.
Leukemia. 2011;25:1050-3.
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THEILGAARD-MONCH K , Boultwood J, Ferrari S, Giannopoulos K, et al
Gene expression profiling in MDS and AML: potential and future avenues.
Leukemia. 2011;25:909-20.
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May 2011

KAKADIA PM , Tizazu B, Mellert G, Harbott J, et al
A novel ABL1 fusion to the SH2 containing inositol phosphatase-1 (SHIP1) in acute lymphoblastic leukemia (ALL).
Leukemia. 2011.
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KIRSCHBAUM MH , Synold T, Stein AS, Tuscano J, et al
A phase 1 trial dose-escalation study of tipifarnib on a week-on, week-off schedule in relapsed, refractory or high-risk myeloid leukemia.
Leukemia. 2011.
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KONSTANDIN N , Bultmann S, Szwagierczak A, Dufour A, et al
Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia.
Leukemia. 2011.
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HEROLD T , Jurinovic V, Metzeler KH, Boulesteix AL, et al
An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia.
Leukemia. 2011.
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OHGAMI RS , Ohgami JK, Pereira IT, Gitana G, et al
Refining the diagnosis of T-cell large granular lymphocytic leukemia by combining distinct patterns of antigen expression with T-cell clonality studies.
Leukemia. 2011.
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LODEWYCK T , Oudshoorn M, van der Holt B, Petersen E, et al
Predictive impact of allele-matching and EBMT risk score for outcome after T-cell depleted unrelated donor transplantation in poor-risk acute leukemia and myelodysplasia.
Leukemia. 2011.
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WAKITA S , Yamaguchi H, Miyake K, Mitamura Y, et al
Importance of c-kit mutation detection method sensitivity in prognostic analyses of t(8;21)(q22;q22) acute myeloid leukemia.
Leukemia. 2011.
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GREIF PA , Yaghmaie M, Konstandin NP, Ksienzyk B, et al
Somatic mutations in acute promyelocytic leukemia (APL) identified by exome sequencing.
Leukemia. 2011.
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SCHOTTE D , Moqadam FA, Lange-Turenhout EA, Chen C, et al
Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia.
Leukemia. 2011.
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BLUM KA , Ruppert AS, Woyach JA, Jones JA, et al
Risk factors for tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with the cyclin-dependent kinase inhibitor, flavopiridol.
Leukemia. 2011.
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MICCI F , Thorsen J, Haugom L, Zeller B, et al
Translocation t(1;16)(p31;q24) rearranging CBFA2T3 is specific for acute erythroid leukemia.
Leukemia. 2011.
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PFIRRMANN M , Hochhaus A, Lauseker M, Saussele S, et al
Recommendations to meet statistical challenges arising from endpoints beyond overall survival in clinical trials on chronic myeloid leukemia.
Leukemia. 2011.
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MERIMS S , Li X, Joe B, Dokouhaki P, et al
Anti-leukemia effect of ex vivo expanded DNT cells from AML patients: a potential novel autologous T-cell adoptive immunotherapy.
Leukemia. 2011.
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BALGOBIND BV , Zwaan CM, Pieters R, Van den Heuvel-Eibrink MM, et al
The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia.
Leukemia. 2011.
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GERBY B , Clappier E, Armstrong F, Deswarte C, et al
Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations.
Leukemia. 2011.
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WICKREMASINGHE RG , Prentice AG, Steele AJ
p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies.
Leukemia. 2011.
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MANSUR MB , Ford AM, van Delft FW, Gonzalez D, et al
Occurrence of identical NOTCH1 mutation in non-twinned sisters with T-cell acute lymphoblastic leukemia.
Leukemia. 2011.
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ECKERT C , Flohr T, Koehler R, Hagedorn N, et al
Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment.
Leukemia. 2011.
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FERRETTI E , Bertolotto M, Deaglio S, Tripodo C, et al
A novel role of the CX(3)CR1/CX(3)CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment.
Leukemia. 2011.
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BLINK M , Buitenkamp TD, van den Heuvel-Eibrink MM, Danen-van Oorschot AA, et al
Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia.
Leukemia. 2011.
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SCHNITTGER S , Bacher U, Kern W, Alpermann T, et al
Prognostic impact of FLT3-ITD load in NPM1 mutated acute myeloid leukemia.
Leukemia. 2011.
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COSCIA M , Pantaleoni F, Riganti C, Vitale C, et al
IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells.
Leukemia. 2011;25:828-37.
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CRADDOCK C , Labopin M, Pillai S, Finke J, et al
Factors predicting outcome after unrelated donor stem cell transplantation in primary refractory acute myeloid leukaemia.
Leukemia. 2011;25:808-13.
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OCCHIONORELLI M , Santoro F, Pallavicini I, Gruszka A, et al
The self-association coiled-coil domain of PML is sufficient for the oncogenic conversion of the retinoic acid receptor (RAR) alpha.
Leukemia. 2011;25:814-20.
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TAMAI H , Miyake K, Takatori M, Miyake N, et al
Activated K-Ras protein accelerates human MLL/AF4-induced leukemo-lymphomogenicity in a transgenic mouse model.
Leukemia. 2011;25:888-91.
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HAFERLACH C , Bacher U, Haferlach T, Dicker F, et al
The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.
Leukemia. 2011;25:874-7.
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April 2011

FABRICIUS D , Breckerbohm L, Vollmer A, Queudeville M, et al
Acute lymphoblastic leukemia cells treated with CpG oligodeoxynucleotides, IL-4 and CD40 ligand facilitate enhanced anti-leukemic CTL responses.
Leukemia. 2011.
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TEUFFEL O , Kuster SP, Hunger SP, Conter V, et al
Dexamethasone versus prednisone for induction therapy in childhood acute lymphoblastic leukemia: a systematic review and meta-analysis.
Leukemia. 2011.
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ABDEL-WAHAB O , Pardanani A, Rampal R, Lasho TL, et al
DNMT3A mutational analysis in primary myelofibrosis, chronic myelomonocytic leukemia and advanced phases of myeloproliferative neoplasms.
Leukemia. 2011.
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KOPTYRA M , Stoklosa T, Hoser G, Glodkowska-Mrowka E, et al
Monoubiquitinated Fanconi anemia D2 (FANCD2-Ub) is required for BCR-ABL1 kinase-induced leukemogenesis.
Leukemia. 2011.
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LEHMANN S , Ravn A, Carlsson L, Antunovic P, et al
Continuing high early death rate in acute promyelocytic leukemia: a population-based report from the Swedish Adult Acute Leukemia Registry.
Leukemia. 2011.
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SHIBA N , Taki T, Park MJ, Nagasawa M, et al
CBL mutation in childhood therapy-related leukemia.
Leukemia. 2011.
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EMERENCIANO M , Meyer C, Macedo-Silva ML, de Meis E, et al
Backtracking to birth of the NUP98-HOXD13 gene fusion in an infant acute myeloid leukemia.
Leukemia. 2011.
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STEELMAN LS , Franklin RA, Abrams SL, Chappell W, et al
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
Leukemia. 2011.
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MENG X , Matlawska-Wasowska K, Girodon F, Mazel T, et al
GSI-I (Z-LLNle-CHO) inhibits gamma-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia.
Leukemia. 2011.
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MITRA AK , Crews K, Pounds S, Cao X, et al
Impact of genetic variation in FKBP5 on clinical response in pediatric acute myeloid leukemia patients: a pilot study.
Leukemia. 2011.
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PARAMESWARAN R , Yu M, Lim M, Groffen J, et al
Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist.
Leukemia. 2011.
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LU J , Ma Y, Kong N, Alipio Z, et al
Dissecting the role of SALL4, a newly identified stem cell factor, in chronic myelogenous leukemia.
Leukemia. 2011.
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ABDEL-WAHAB O , Pardanani A, Patel J, Wadleigh M, et al
Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms.
Leukemia. 2011.
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SILVA A , Girio A, Cebola I, Santos CI, et al
Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells.
Leukemia. 2011.
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KRALJACIC BC , Arguello M, Amri A, Cormack G, et al
Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens.
Leukemia. 2011.
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ALMEIDA J , Nieto WG, Teodosio C, Pedreira CE, et al
CLL-like B-lymphocytes are systematically present at very low numbers in peripheral blood of healthy adults.
Leukemia. 2011;25:718-22.
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SCHNITTGER S , Bacher U, Haferlach C, Alpermann T, et al
Characterization of NPM1-mutated AML with a history of myelodysplastic syndromes or myeloproliferative neoplasms.
Leukemia. 2011;25:615-21.
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FLACH J , Dicker F, Schnittger S, Schindela S, et al
An accumulation of cytogenetic and molecular genetic events characterizes the progression from MDS to secondary AML: an analysis of 38 paired samples analyzed by cytogenetics, molecular mutation analysis and SNP microarray profiling.
Leukemia. 2011;25:713-8.
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March 2011

MARTELLI AM , Evangelisti C, Chappell W, Abrams SL, et al
Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
Leukemia. 2011.
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HOCKLEY SL , Morgan GJ, Leone PE, Walker BA, et al
High-resolution genomic profiling in hairy cell leukemia-variant compared with typical hairy cell leukemia.
Leukemia. 2011.
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WESOLOWSKA A , Dalgaard MD, Borst L, Gautier L, et al
Cost-effective multiplexing before capture allows screening of 25 000 clinically relevant SNPs in childhood acute lymphoblastic leukemia.
Leukemia. 2011.
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BRANDWEIN JM , Hedley DW, Chow S, Schimmer AD, et al
A phase I/II study of imatinib plus reinduction therapy for c-kit-positive relapsed/refractory acute myeloid leukemia: inhibition of Akt activation correlates with complete response.
Leukemia. 2011.
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MIEDEMA KG , Te Poele EM, Tissing WJ, Postma DS, et al
Association of polymorphisms in the TLR4 gene with the risk of developing neutropenia in children with leukemia.
Leukemia. 2011.
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GRAND FH , Waghorn K, Ernst T, Ohyashiki K, et al
The t(4;9)(q11;q33) fuses CEP110 to KIT in a case of acute myeloid leukemia.
Leukemia. 2011.
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SAITO Y , Nakahata S, Yamakawa N, Kaneda K, et al
CD52 as a molecular target for immunotherapy to treat acute myeloid leukemia with high EVI1 expression.
Leukemia. 2011.
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YU L , Slovak ML, Mannoor K, Chen C, et al
Microarray detection of multiple recurring submicroscopic chromosomal aberrations in pediatric T-cell acute lymphoblastic leukemia.
Leukemia. 2011.
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DURIG J , Duhrsen U, Klein-Hitpass L, Worm J, et al
The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia.
Leukemia. 2011.
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WALSBY E , Lazenby M, Pepper C, Burnett AK, et al
The cyclin-dependent kinase inhibitor SNS-032 has single agent activity in AML cells and is highly synergistic with cytarabine.
Leukemia. 2011;25:411-9.
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CHEN Z , Lopez-Ramos DA, Yoshihara E, Maeda Y, et al
Thioredoxin-binding protein-2 (TBP-2/VDUP1/TXNIP) regulates T-cell sensitivity to glucocorticoid during HTLV-I-induced transformation.
Leukemia. 2011;25:440-8.
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LANGE T , Hubmann M, Burkhardt R, Franke GN, et al
Monitoring of WT1 expression in PB and CD34(+) donor chimerism of BM predicts early relapse in AML and MDS patients after hematopoietic cell transplantation with reduced-intensity conditioning.
Leukemia. 2011;25:498-505.
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February 2011

SHAH N , Decker WK, Lapushin R, Xing D, et al
HLA homozygosity and haplotype bias among patients with chronic lymphocytic leukemia: implications for disease control by physiological immune surveillance.
Leukemia. 2011.
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PETERSON LF , Mitrikeska E, Giannola D, Lui Y, et al
p53 stabilization induces apoptosis in chronic myeloid leukemia blast crisis cells.
Leukemia. 2011.
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GROSSMANN V , Kohlmann A, Eder C, Haferlach C, et al
Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance.
Leukemia. 2011.
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GREIF PA , Eck SH, Konstandin NP, Benet-Pages A, et al
Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing.
Leukemia. 2011.
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GANDILLET A , Park S, Lassailly F, Griessinger E, et al
Heterogeneous sensitivity of human acute myeloid leukemia to beta-catenin down-modulation.
Leukemia. 2011.
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EVANGELISTI C , Ricci F, Tazzari P, Tabellini G, et al
Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.
Leukemia. 2011.
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OELSCHLAEGEL U , Mohr B, Schaich M, Kroschinsky F, et al
Reply to: 'Flow cytometric identification of acute myeloid leukemia with limited differentiation and NPM1 type A mutation: a new biologically defined entity' by Kern et al.
Leukemia. 2011.
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CHEVALLIER P , Labopin M, Turlure P, Prebet T, et al
A new Leukemia Prognostic Scoring System for refractory/relapsed adult acute myelogeneous leukaemia patients: a GOELAMS study.
Leukemia. 2011.
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PIGAZZI M , Masetti R, Bresolin S, Beghin A, et al
MLL partner genes drive distinct gene expression profiles and genomic alterations in pediatric acute myeloid leukemia: an AIEOP study.
Leukemia. 2011.
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PORTER CC , Baturin D, Choudhary R, Degregori J, et al
Relative fitness of hematopoietic progenitors influences leukemia progression.
Leukemia. 2011.
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VANDEWOESTYNE ML , Pede VC, Lambein KY, Dhaenens MF, et al
Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles.
Leukemia. 2011.
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BAER MR , George SL, Sanford BL, Mrozek K, et al
Escalation of daunorubicin and addition of etoposide in the ADE regimen in acute myeloid leukemia patients aged 60 years and older: Cancer and Leukemia Group B Study 9720.
Leukemia. 2011.
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TUVE S , Gayoso J, Scheid C, Radke J, et al
Haploidentical bone marrow transplantation with post-grafting cyclophosphamide: multicenter experience with an alternative salvage strategy.
Leukemia. 2011.
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HUBER S , Oelsner M, Decker T, Zum Buschenfelde CM, et al
Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1.
Leukemia. 2011.
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JABBOUR E , Deininger M, Hochhaus A
Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia.
Leukemia. 2011;25:385.
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OTTEN J , Schmitz L, Vettorazzi E, Schultze A, et al
Expression of TGF-beta receptor ALK-5 has a negative impact on outcome of patients with acute myeloid leukemia.
Leukemia. 2011;25:375-9.
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HUANG Q , Snyder DS, Chu P, Gaal KK, et al
PDGFRA rearrangement leading to hyper-eosinophilia, T-lymphoblastic lymphoma, myeloproliferative neoplasm and precursor B-cell acute lymphoblastic leukemia.
Leukemia. 2011;25:371-5.
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ZALIOVA M , Madzo J, Cario G, Trka J, et al
Revealing the role of TEL/AML1 for leukemic cell survival by RNAi-mediated silencing.
Leukemia. 2011;25:313-20.
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REDDY MM , Fernandes MS, Salgia R, Levine RL, et al
NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
Leukemia. 2011;25:281-9.
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DE BOER J , Yeung J, Ellu J, Ramanujachar R, et al
The E2A-HLF oncogenic fusion protein acts through Lmo2 and Bcl-2 to immortalize hematopoietic progenitors.
Leukemia. 2011;25:321-30.
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MODI H , Li L, Chu S, Rossi J, et al
Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells.
Leukemia. 2011;25:305-12.
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ROSS DM , Hughes TP, Melo JV
Do we have to kill the last CML cell?
Leukemia. 2011;25:193-200.
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January 2011

GROSSMANN V , Kohlmann A, Zenger M, Schindela S, et al
A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases.
Leukemia. 2011.
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ANGUILLE S , Lion E, Willemen Y, Van Tendeloo VF, et al
Interferon-alpha in acute myeloid leukemia: an old drug revisited.
Leukemia. 2011.
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COLES SJ , Wang EC, Man S, Hills RK, et al
CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia.
Leukemia. 2011.
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MASIERO M , Minuzzo S, Pusceddu I, Moserle L, et al
Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells.
Leukemia. 2011.
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LANDRETTE SF , Madera D, He F, Castilla LH, et al
The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.
Leukemia. 2011.
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FARAG SS , Wood LL, Schwartz JE, Srivastava S, et al
Phase I trial and pharmacokinetic study of high-dose clofarabine and busulfan and allogeneic stem cell transplantation in adults with high-risk and refractory acute leukemia.
Leukemia. 2011.
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YONG AS , Stephens N, Weber G, Li Y, et al
Improved outcome following allogeneic stem cell transplantation in chronic myeloid leukemia is associated with higher expression of BMI-1 and immune responses to BMI-1 protein.
Leukemia. 2011.
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BELLONI E , Shing D, Tapinassi C, Viale A, et al
In vivo expression of an aberrant MYB-GATA1 fusion induces leukemia in the presence of GATA1 reduced levels.
Leukemia. 2011.
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GROSSMANN V , Kohlmann A, Klein HU, Schindela S, et al
Targeted next-generation sequencing detects point mutations, insertions, deletions and balanced chromosomal rearrangements as well as identifies novel leukemia-specific fusion genes in a single procedure.
Leukemia. 2011.
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BENE MC , Nebe T, Bettelheim P, Buldini B, et al
Immunophenotyping of acute leukemia and lymphoproliferative disorders: a consensus proposal of the European LeukemiaNet Work Package 10.
Leukemia. 2011.
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ZACHARIADIS V , Gauffin F, Kuchinskaya E, Heyman M, et al
The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial.
Leukemia. 2011.
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BHATTACHARYA N , Diener S, Idler IS, Barth TF, et al
Non-malignant B cells and chronic lymphocytic leukemia cells induce a pro-survival phenotype in CD14(+) cells from peripheral blood.
Leukemia. 2011.
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HASEGAWA H , Yamada Y, Tsukasaki K, Mori N, et al
LBH589, a deacetylase inhibitor, induces apoptosis in adult T-cell leukemia/lymphoma cells via activation of a novel RAIDD-caspase-2 pathway.
Leukemia. 2011.
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CRISTOBAL I , Garcia-Orti L, Cirauqui C, Alonso MM, et al
PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect.
Leukemia. 2011.
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PLESS B , Oehm C, Knauer S, Stauber RH, et al
The heterodimerization domains of MLL-FYRN and FYRC-are potential target structures in t(4;11) leukemia.
Leukemia. 2011.
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SABORIT-VILLARROYA I , Vaisitti T, Rossi D, D'Arena G, et al
E2A is a transcriptional regulator of CD38 expression in chronic lymphocytic leukemia.
Leukemia. 2011.
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NICOLAS E , Ramus C, Berthier S, Arlotto M, et al
Expression of S100A8 in leukemic cells predicts poor survival in de novo AML patients.
Leukemia. 2011;25:57-65.
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CHEN SH , Yang W, Fan Y, Stocco G, et al
A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.
Leukemia. 2011;25:66-74.
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TA VB , de Haan AB, de Bruijn MJ, Dingjan GM, et al
Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity.
Leukemia. 2011;25:48-56.
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BENEDIKT A , Baltruschat S, Scholz B, Bursen A, et al
The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.
Leukemia. 2011;25:135-44.
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LE GARFF-TAVERNIER M , Decocq J, de Romeuf C, Parizot C, et al
Analysis of CD16+CD56dim NK cells from CLL patients: evidence supporting a therapeutic strategy with optimized anti-CD20 monoclonal antibodies.
Leukemia. 2011;25:101-9.
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SJOGREN AK , Andersson KM, Khan O, Olofsson FJ, et al
Inactivating GGTase-I reduces disease phenotypes in a mouse model of K-RAS-induced myeloproliferative disease.
Leukemia. 2011;25:186-9.
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PIGAZZI M , Ferrari G, Masetti R, Falini B, et al
Low prevalence of IDH1 gene mutation in childhood AML in Italy.
Leukemia. 2011;25:173-4.
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BARDINI M , Galbiati M, Lettieri A, Bungaro S, et al
Implementation of array based whole-genome high-resolution technologies confirms the absence of secondary copy-number alterations in MLL-AF4-positive infant ALL patients.
Leukemia. 2011;25:175-8.
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December 2010

SAMANTA A , Perazzona B, Chakraborty S, Sun X, et al
Janus kinase 2 regulates Bcr-Abl signaling in chronic myeloid leukemia.
Leukemia. 2010.
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PARKER H , Rose-Zerilli MJ, Parker A, Chaplin T, et al
13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia.
Leukemia. 2010.
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YU L , Reader JC, Chen C, Zhao XF, et al
Activation of a novel palmitoyltransferase ZDHHC14 in acute biphenotypic leukemia and subsets of acute myeloid leukemia.
Leukemia. 2010.
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STOLZEL F , Pfirrmann M, Aulitzky WE, Kaufmann M, et al
Risk stratification using a new prognostic score for patients with secondary acute myeloid leukemia: results of the prospective AML96 trial.
Leukemia. 2010.
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BUENO C , Montes R, Catalina P, Rodriguez R, et al
Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.
Leukemia. 2010.
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ROSSIGNOL J , Michallet AS, Oberic L, Picard M, et al
Rituximab-cyclophosphamide-dexamethasone combination in the management of autoimmune cytopenias associated with chronic lymphocytic leukemia.
Leukemia. 2010.
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FERRANDO A
NOTCH mutations as prognostic markers in T-ALL.
Leukemia. 2010;24:2003-4.
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KOX C , Zimmermann M, Stanulla M, Leible S, et al
The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function.
Leukemia. 2010;24:2005-13.
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BALGOBIND BV , Zwaan CM, Reinhardt D, Arentsen-Peters TJ, et al
High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome.
Leukemia. 2010;24:2048-55.
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November 2010

QUINTAS-CARDAMA A , Santos FP, Garcia-Manero G
Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia.
Leukemia. 2010.
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QUERE R , Andradottir S, Brun AC, Zubarev RA, et al
High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event.
Leukemia. 2010.
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STUMPEL DJ , Schotte D, Lange-Turenhout EA, Schneider P, et al
Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale.
Leukemia. 2010.
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WAANDERS E , van der Velden VH, van der Schoot CE, van Leeuwen FN, et al
Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia.
Leukemia. 2010.
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BIXBY D , Talpaz M
Seeking the causes and solutions to imatinib-resistance in chronic myeloid leukemia.
Leukemia. 2010.
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CHOU WC , Lei WC, Ko BS, Hou HA, et al
The prognostic impact and stability of Isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia.
Leukemia. 2010.
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BASTIAN L , Einsiedel HG, Henze G, Seeger K, et al
The sequence of application of methotrexate and histone deacetylase inhibitors determines either a synergistic or an antagonistic response in childhood acute lymphoblastic leukemia cells.
Leukemia. 2010.
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JEON EK , Lim J, Kim M, Yahng SA, et al
The first case of acute lymphoblastic leukemia with the e19a2 BCR-ABL1 transcript: imatinib therapy followed by unrelated donor transplantation induces a durable molecular response.
Leukemia. 2010.
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BLALOCK WL , Bavelloni A, Piazzi M, Tagliavini F, et al
Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress.
Leukemia. 2010.
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KAKO S , Morita S, Sakamaki H, Ogawa H, et al
A decision analysis of allogeneic hematopoietic stem cell transplantation in adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia in first remission who have an HLA-matched sibling donor.
Leukemia. 2010.
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LANGEMEIJER SM , Jansen JH, Hooijer J, van Hoogen P, et al
TET2 mutations in childhood leukemia.
Leukemia. 2010.
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WIERDA WG , Castro JE, Aguillon R, Sampath D, et al
A phase I study of immune gene therapy for patients with CLL using a membrane-stable, humanized CD154.
Leukemia. 2010;24:1893-900.
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MOHTY M , Labopin M, Balere ML, Socie G, et al
Antithymocyte globulins and chronic graft-vs-host disease after myeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors: a report from the Societe Francaise de Greffe de Moelle et de Therapie Cellulaire.
Leukemia. 2010;24:1867-74.
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BROWN JR , Abramson J, Hochberg E, Mikler E, et al
A phase I study of lenalidomide in combination with fludarabine and rituximab in previously untreated CLL/SLL.
Leukemia. 2010;24:1972-5.
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COSTA ES , Pedreira CE, Barrena S, Lecrevisse Q, et al
Automated pattern-guided principal component analysis vs expert-based immunophenotypic classification of B-cell chronic lymphoproliferative disorders: a step forward in the standardization of clinical immunophenotyping.
Leukemia. 2010;24:1927-33.
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OANCEA C , Ruster B, Henschler R, Puccetti E, et al
The t(6;9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic stem cells for leukemogenic transformation.
Leukemia. 2010;24:1910-9.
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WHITE DL , Saunders VA, Dang P, Engler J, et al
OCT-1 activity measurement provides a superior imatinib response predictor than screening for single-nucleotide polymorphisms of OCT-1.
Leukemia. 2010;24:1962-5.
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October 2010

VAN VLIERBERGHE P , Patel J, Abdel-Wahab O, Lobry C, et al
PHF6 mutations in adult acute myeloid leukemia.
Leukemia. 2010.
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SHEHATA M , Demirtas D, Schnabl S, Hilgarth M, et al
Sequential gene expression profiling during treatment for identification of predictive markers and novel therapeutic targets in chronic lymphocytic leukemia.
Leukemia. 2010.
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SOVERINI S , Score J, Iacobucci I, Poerio A, et al
IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis.
Leukemia. 2010.
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CARNEY DA , Westerman DA, Tam CS, Milner A, et al
Therapy-related myelodysplastic syndrome and acute myeloid leukemia following fludarabine combination chemotherapy.
Leukemia. 2010.
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KRUSE U , Pallasch CP, Bantscheff M, Eberhard D, et al
Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells.
Leukemia. 2010.
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MIZUTA S , Matsuo K, Yagasaki F, Yujiri T, et al
Pre-transplant imatinib-based therapy improves the outcome of allogeneic hematopoietic stem cell transplantation for BCR-ABL-positive acute lymphoblastic leukemia.
Leukemia. 2010.
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HANDGRETINGER R , Zugmaier G, Henze G, Kreyenberg H, et al
Complete remission after blinatumomab-induced donor T-cell activation in three pediatric patients with post-transplant relapsed acute lymphoblastic leukemia.
Leukemia. 2010.
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CARAMAZZA D , Begna KH, Gangat N, Vaidya R, et al
Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: a single center study of 433 patients.
Leukemia. 2010.
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LIN TC , Hou HA, Chou WC, Ou DL, et al
CEBPA methylation as a prognostic biomarker in patients with de novo acute myeloid leukemia.
Leukemia. 2010.
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LIU L , Yang M, Kang R, Wang Z, et al
HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells.
Leukemia. 2010.
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PARDANANI A , Lasho T, Finke C, Oh ST, et al
LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations.
Leukemia. 2010;24:1713-8.
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MAKISHIMA H , Jankowska AM, Tiu RV, Szpurka H, et al
Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies.
Leukemia. 2010;24:1799-804.
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LUO H , Quan H, Xie C, Xu Y, et al
HH-GV-678, a novel selective inhibitor of Bcr-Abl, outperforms imatinib and effectively overrides imatinib resistance.
Leukemia. 2010;24:1807-9.
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MICHALLET M , Sobh M, Milligan D, Morisset S, et al
The impact of HLA matching on long-term transplant outcome after allogeneic hematopoietic stem cell transplantation for CLL: a retrospective study from the EBMT registry.
Leukemia. 2010;24:1725-31.
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SCORE J , Calasanz MJ, Ottman O, Pane F, et al
Analysis of genomic breakpoints in p190 and p210 BCR-ABL indicate distinct mechanisms of formation.
Leukemia. 2010;24:1742-50.
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GESSNER A , Thomas M, Castro PG, Buchler L, et al
Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
Leukemia. 2010;24:1751-9.
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WUNDERLICH M , Chou FS, Link KA, Mizukawa B, et al
AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3.
Leukemia. 2010;24:1785-8.
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September 2010

LEE S , Chung NG, Cho BS, Eom KS, et al
Donor-specific differences in long-term outcomes of myeloablative transplantation in adults with Philadelphia-negative acute lymphoblastic leukemia.
Leukemia. 2010.
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ROBIN M , Sanz GF, Ionescu I, Rio B, et al
Unrelated cord blood transplantation in adults with myelodysplasia or secondary acute myeloblastic leukemia: a survey on behalf of Eurocord and CLWP of EBMT.
Leukemia. 2010.
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SULJAGIC M , Laurenti L, Tarnani M, Alam M, et al
Reduced expression of the tumor suppressor PHLPP1 enhances the antiapoptotic B-cell receptor signal in chronic lymphocytic leukemia B-cells.
Leukemia. 2010.
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CLAPPIER E , Collette S, Grardel N, Girard S, et al
NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.
Leukemia. 2010.
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JABBOUR E , Deininger M, Hochhaus A
Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia.
Leukemia. 2010.
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BAKER KS , Ness KK, Weisdorf D, Francisco L, et al
Late effects in survivors of acute leukemia treated with hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study.
Leukemia. 2010.
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ZENZ T , Vollmer D, Trbusek M, Smardova J, et al
TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations.
Leukemia. 2010.
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SLOMA I , Jiang X, Eaves AC, Eaves CJ, et al
Insights into the stem cells of chronic myeloid leukemia.
Leukemia. 2010.
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CARAMAZZA D , Lasho TL, Finke CM, Gangat N, et al
IDH mutations and trisomy 8 in myelodysplastic syndromes and acute myeloid leukemia.
Leukemia. 2010.
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ZUURBIER L , Homminga I, Calvert V, Winkel MT, et al
NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.
Leukemia. 2010.
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WEINBERG OK , Arber DA
Mixed-phenotype acute leukemia: historical overview and a new definition.
Leukemia. 2010.
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ABRAHAMSEN IW , Stronen E, Walchli S, Johansen JN, et al
Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif.
Leukemia. 2010.
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WEISBERG E , Ray A, Barrett R, Nelson E, et al
Smac mimetics: implications for enhancement of targeted therapies in leukemia.
Leukemia. 2010.
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THEPOT S , Zhou J, Perrot A, Robin M, et al
The graft-versus-leukemia effect is mainly restricted to NIH-defined chronic graft-versus-host disease after reduced intensity conditioning before allogeneic stem cell transplantation.
Leukemia. 2010.
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GROSS E , L'faqihi-Olive FE, Ysebaert L, Brassac M, et al
B-chronic lymphocytic leukemia chemoresistance involves innate and acquired leukemic side population cells.
Leukemia. 2010.
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ROSS DM , Branford S, Seymour JF, Schwarer AP, et al
Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR.
Leukemia. 2010.
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WEHNER R , Schumacher P, Bornhauser M, Ehninger G, et al
Acute myeloid leukemia cells fail to activate native human dendritic cells: a potential mechanism of immune evasion.
Leukemia. 2010.
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CHEVALIER N , Solari ML, Becker H, Pantic M, et al
Robust in vivo differentiation of t(8;21)-positive acute myeloid leukemia blasts to neutrophilic granulocytes induced by treatment with dasatinib.
Leukemia. 2010.
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BULGAR AD , Snell M, Donze JR, Kirkland EB, et al
Targeting base excision repair suggests a new therapeutic strategy of fludarabine for the treatment of chronic lymphocytic leukemia.
Leukemia. 2010.
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ANDRIKOVICS H , Nahajevszky S, Koszarska M, Meggyesi N, et al
JAK2 46/1 haplotype analysis in myeloproliferative neoplasms and acute myeloid leukemia.
Leukemia. 2010.
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PASSAMONTI F , Rumi E, Pietra D, Elena C, et al
A prospective study of 338 patients with polycythemia vera: the impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications.
Leukemia. 2010;24:1574-9.
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MOWERY YM , Weinberg JB, Kennedy MN, Bond KM, et al
LMP-420: a novel purine nucleoside analog with potent cytotoxic effects for CLL cells and minimal toxicity for normal hematopoietic cells.
Leukemia. 2010;24:1580-7.
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August 2010

ARGIROPOULOS B , Palmqvist L, Imren S, Miller M, et al
Meis1 disrupts the genomic imprint of Dlk1 in a NUP98-HOXD13 leukemia model.
Leukemia. 2010.
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GRANT H , Jiang X, Stebbing J, Foroni L, et al
Analysis of BCR-ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype.
Leukemia. 2010.
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MORISOT S , Wayne AS, Bohana-Kashtan O, Kaplan IM, et al
High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias.
Leukemia. 2010.
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COLLINS-UNDERWOOD JR , Mullighan CG
Genomic profiling of high-risk acute lymphoblastic leukemia.
Leukemia. 2010.
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OELSCHLAEGEL U , Koch S, Mohr B, Schaich M, et al
Rapid flow cytometric detection of aberrant cytoplasmic localization of nucleophosmin (NPMc) indicating mutant NPM1 gene in acute myeloid leukemia.
Leukemia. 2010.
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YIN B , Tsai ML, Hasz DE, Rathe SK, et al
A microarray study of altered gene expression in Ara-C resistance in acute myeloid leukemia.
Leukemia. 2010;24:1543.
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CHEN J , Li Y, Doedens M, Wang P, et al
Functional differences between myeloid leukemia-initiating and transient leukemia cells in Down's syndrome.
Leukemia. 2010;24:1542.
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PINKEL D
Response to letter by Pulsipher et al.
Leukemia. 2010;24:1532-3.
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PRATZ KW , Cho E, Levis MJ, Karp JE, et al
A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemias.
Leukemia. 2010;24:1437-44.
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BHAROS A , Jong AJ, Manton N, Venn N, et al
Bone marrow fibrosis and vascular density lack prognostic significance in childhood acute lymphoblastic leukaemia.
Leukemia. 2010;24:1537-8.
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SANDER A , Zimmermann M, Dworzak M, Fleischhack G, et al
Consequent and intensified relapse therapy improved survival in pediatric AML: results of relapse treatment in 379 patients of three consecutive AML-BFM trials.
Leukemia. 2010;24:1422-8.
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VON BUBNOFF N , Rummelt C, Menzel H, Sigl M, et al
Identification of a secondary FLT3/A848P mutation in a patient with FLT3-ITD-positive blast phase CMML and response to sunitinib and sorafenib.
Leukemia. 2010;24:1523-5.
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MAREGA M , Piazza RG, Pirola A, Redaelli S, et al
BCR and BCR-ABL regulation during myeloid differentiation in healthy donors and in chronic phase/blast crisis CML patients.
Leukemia. 2010;24:1445-9.
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DICKER F , Haferlach C, Sundermann J, Wendland N, et al
Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1 and NRAS in 269 patients with MDS or secondary AML.
Leukemia. 2010;24:1528-32.
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July 2010

SHI Y , Tomic J, Wen F, Shaha S, et al
Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia.
Leukemia. 2010.
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VAN DER VELDEN VH , van der Sluijs-Geling A, Gibson BE, Te Marvelde JG, et al
Clinical significance of flowcytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol.
Leukemia. 2010.
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RIBATTI D
Bone marrow vascular niche and the control of tumor growth in hematological malignancies.
Leukemia. 2010;24:1247-8.
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BURDA P , Laslo P, Stopka T
The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis.
Leukemia. 2010;24:1249-57.
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TEFFERI A , Lasho TL, Abdel-Wahab O, Guglielmelli P, et al
IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis.
Leukemia. 2010;24:1302-9.
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WEISBERG E , Deng X, Choi HG, Barrett R, et al
Beneficial effects of combining a type II ATP competitive inhibitor with an allosteric competitive inhibitor of BCR-ABL for the treatment of imatinib-sensitive and imatinib-resistant CML.
Leukemia. 2010;24:1375-8.
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VAN DEN ANCKER W , Terwijn M, Westers TM, Merle PA, et al
Acute leukemias of ambiguous lineage: diagnostic consequences of the WHO2008 classification.
Leukemia. 2010;24:1392-6.
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KUIPER RP , Waanders E, van der Velden VH, van Reijmersdal SV, et al
IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.
Leukemia. 2010;24:1258-64.
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