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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Leukemia

Free Subscription Articles published in Leukemia Retrieve available abstracts of 508 articles: HTML format

Single Articles

July 2008
1. SHIMONI A , Leiba M, Schleuning M, Martineau G, et al
   Prior treatment with the tyrosine kinase inhibitors dasatinib and nilotinib allows stem cell transplantation (SCT) in a less advanced disease phase and does not increase SCT Toxicity in patients with chronic myelogenous leukemia and philadelphia positive
   Leukemia. 2008;.
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2. BOWEN D , Groves MJ, Burnett AK, Patel Y, et al
   TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis.
   Leukemia. 2008;.
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3. PEREZ-GALAN P , Roue G, Lopez-Guerra M, Nguyen M, et al
   BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells.
   Leukemia. 2008;.
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4. CARDOSO BA , Martins LR, Santos CI, Nadler LM, et al
   Interleukin-4 stimulates proliferation and growth of T-cell acute lymphoblastic leukemia cells by activating mTOR signaling.
   Leukemia. 2008;.
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   June 2008
5. MOHTY M , de Lavallade H, El-Cheikh J, Ladaique P, et al
   Reduced intensity conditioning allogeneic stem cell transplantation for patients with acute myeloid leukemia: long term results of a 'donor' versus 'no donor' comparison.
   Leukemia. 2008;.
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6. APPEL IM , Kazemier KM, Boos J, Lanvers C, et al
   Pharmacokinetic, pharmacodynamic and intracellular effects of PEG-asparaginase in newly diagnosed childhood acute lymphoblastic leukemia: results from a single agent window study.
   Leukemia. 2008;.
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7. VOSO MT , Hohaus S, Guidi F, Fabiani E, et al
   Prognostic role of glutathione S-transferase polymorphisms in acute myeloid leukemia.
   Leukemia. 2008;.
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8. GOEMANS BF , Zwaan CM, Vijverberg SJ, Loonen AH, et al
   Large interindividual differences in cellular sensitivity to calicheamicin may influence gemtuzumab ozogamicin response in acute myeloid leukemia.
   Leukemia. 2008;.
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9. HIWATARI M , Ono R, Taki T, Hishiya A, et al
   Novel gain-of-function mutation in the extracellular domain of the PDGFRA gene in infant acute lymphoblastic leukemia with t(4;11)(q21;q23).
   Leukemia. 2008;.
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10. GRUHN B , Taub JW, Ge Y, Beck JF, et al
    Prenatal origin of childhood acute lymphoblastic leukemia, association with birth weight and hyperdiploidy.
    Leukemia. 2008;.
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11. CHAUBEY A , Karanti S, Rai D, Oh T, et al
    MicroRNAs and deletion of the derivative chromosome 9 in chronic myeloid leukemia.
    Leukemia. 2008;.
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12. FELDMAN EJ , Cortes J, Deangelo DJ, Holyoake T, et al
    On the use of lonafarnib in myelodysplastic syndrome and chronic myelomonocytic leukemia.
    Leukemia. 2008;.
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13. YONG AS , Keyvanfar K, Eniafe R, Savani BN, et al
    Hematopoietic stem cells and progenitors of chronic myeloid leukemia express leukemia-associated antigens: implications for the graft-versus-leukemia effect and peptide vaccine-based immunotherapy.
    Leukemia. 2008;.
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14. EMANUEL PD
    Juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
    Leukemia. 2008;.
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15. KUANG SQ , Tong WG, Yang H, Lin W, et al
    Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.
    Leukemia. 2008;.
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16. HAFERLACH C , Dicker F, Herholz H, Schnittger S, et al
    Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype.
    Leukemia. 2008;.
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17. TEFFERI A , Killmann NM
    Globalization of treatment strategies in leukemia: challenges and responsibilities.
    Leukemia. 2008;22:1093-4.
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18. CILLONI D , Messa F, Rosso V, Arruga F, et al
    Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations.
    Leukemia. 2008;22:1234-40.
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19. QUINTAS-CARDAMA A , Tong W, Manshouri T, Vega F, et al
    Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies.
    Leukemia. 2008;22:1117-24.
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20. ZHANG H , Trachootham D, Lu W, Carew J, et al
    Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism.
    Leukemia. 2008;22:1191-9.
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21. KARACHUNSKIY A , Herold R, von Stackelberg A, Miakova N, et al
    Results of the first randomized multicentre trial on childhood acute lymphoblastic leukaemia in Russia.
    Leukemia. 2008;22:1144-53.
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22. BENETATOS L , Dasoula A, Syed N, Hatzimichael E, et al
    Methylation analysis of the von Hippel-Lindau gene in acute myeloid leukaemia and myelodysplastic syndromes.
    Leukemia. 2008;22:1293-5.
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23. LISO A , Bogliolo A, Freschi V, Martelli MP, et al
    In human genome, generation of a nuclear export signal through duplication appears unique to nucleophosmin (NPM1) mutations and is restricted to AML.
    Leukemia. 2008;22:1285-9.
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24. TAKADA S , Yamashita Y, Berezikov E, Hatanaka H, et al
    MicroRNA expression profiles of human leukemias.
    Leukemia. 2008;22:1274-8.
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    May 2008
25. AGARWAL A , Eide CA, Harlow A, Corbin AS, et al
    An activating KRAS mutation in imatinib-resistant chronic myeloid leukemia.
    Leukemia. 2008;.
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26. MODLICH U , Schambach A, Brugman MH, Wicke DC, et al
    Leukemia induction after a single retroviral vector insertion in Evi1 or Prdm16.
    Leukemia. 2008;.
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27. CHAPUY B , Koch R, Radunski U, Corsham S, et al
    Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration.
    Leukemia. 2008;.
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28. CAOCCI G , Atzeni S, Orru N, Azzena L, et al
    Gynecomastia in a male after dasatinib treatment for chronic myeloid leukemia.
    Leukemia. 2008;.
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29. GIEBEL S , Nowak I, Wojnar J, Krawczyk-Kulis M, et al
    Association of KIR2DS4 and its variant KIR1D with leukemia.
    Leukemia. 2008;.
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30. VERHEYDEN S , Demanet C
    Reply to: Association of KIR2DS4 and its variant KIR1D with leukemia.
    Leukemia. 2008;.
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31. CHAPIRO E , Radford-Weiss I, Bastard C, Luquet I, et al
    The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia.
    Leukemia. 2008;.
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32. FALINI B
    Therapy-related acute myeloid leukaemia with mutated NPM1: treatment induced or de novo in origin?
    Leukemia. 2008;22:891-2.
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33. CARELLA AM
    Interferon-alpha is able to maintain complete molecular remission induced by imatinib after its discontinuation.
    Leukemia. 2008;22:1090-1.
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34. THOMAS EK , Cancelas JA, Zheng Y, Williams DA, et al
    Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis.
    Leukemia. 2008;22:898-904.
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35. FRONKOVA E , Mejstrikova E, Avigad S, Chik KW, et al
    Minimal residual disease (MRD) analysis in the non-MRD-based ALL IC-BFM 2002 protocol for childhood ALL: is it possible to avoid MRD testing?
    Leukemia. 2008;22:989-97.
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36. TANG YS , Zhang YP, Xu P
    hNUDC promotes the cell proliferation and differentiation in a leukemic cell line via activation of the thrombopoietin receptor (Mpl).
    Leukemia. 2008;22:1018-25.
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37. POGGI A , Catellani S, Bruzzone A, Caligaris-Cappio F, et al
    Lack of the leukocyte-associated Ig-like receptor-1 expression in high-risk chronic lymphocytic leukaemia results in the absence of a negative signal regulating kinase activation and cell division.
    Leukemia. 2008;22:980-8.
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38. BROMIDGE T , Johnson S, Howe D
    Spectrum of p53 mutations in low-grade B-cell malignancies.
    Leukemia. 2008;22:1071-3.
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39. HUSSEIN K , Bock O, Theophile K, Seegers A, et al
    Chronic myeloproliferative diseases with concurrent BCR-ABL junction and JAK2V617F mutation.
    Leukemia. 2008;22:1059-62.
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40. ABUSEDRA A , Joshi R, Bybee A, Apperley JF, et al
    V lambda genes in chronic lymphocytic leukaemia: highly skewed V gene segment usage with similar CDR3 sequences.
    Leukemia. 2008;22:1073-5.
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41. BUGGINS AG , Patten PE, Richards J, Thomas NS, et al
    Tumor-derived IL-6 may contribute to the immunological defect in CLL.
    Leukemia. 2008;22:1084-7.
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42. TSCHAN MP , Gullberg U, Shan D, Torbett BE, et al
    The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias.
    Leukemia. 2008;22:1087-90.
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43. SUN X , Li Y, Yu W, Wang B, et al
    MT1-MMP as a downstream target of BCR-ABL/ABL interactor 1 signaling: polarized distribution and involvement in BCR-ABL-stimulated leukemic cell migration.
    Leukemia. 2008;22:1053-6.
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    April 2008
44. RABBAT A , Chaoui D, Lefebvre A, Roche N, et al
    Is BAL useful in patients with acute myeloid leukemia admitted in ICU for severe respiratory complications?
    Leukemia. 2008;.
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45. KONG Y , Yoshida S, Saito Y, Doi T, et al
    CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL.
    Leukemia. 2008;.
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46. BURCU M , O'Loughlin KL, Ford LA, Baer MR, et al
    Amonafide L-malate is not a substrate for multidrug resistance proteins in secondary acute myeloid leukemia.
    Leukemia. 2008;.
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47. RUTTEN CE , van Luxemburg-Heijs SA, Griffioen M, Marijt EW, et al
    HLA-DP as specific target for cellular immunotherapy in HLA class II-expressing B-cell leukemia.
    Leukemia. 2008;.
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48. RITGEN M , Bottcher S, Stilgenbauer S, Bunjes D, et al
    Quantitative MRD monitoring identifies distinct GVL response patterns after allogeneic stem cell transplantation for chronic lymphocytic leukemia: results from the GCLLSG CLL3X trial.
    Leukemia. 2008;.
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49. HOCHHAUS A , Baccarani M, Deininger M, Apperley JF, et al
    Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib.
    Leukemia. 2008;.
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50. BONHOURE E , Lauret A, Barnes DJ, Martin C, et al
    Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells.
    Leukemia. 2008;.
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51. BECKER H , Pfeifer D, Afonso JD, Nimer SD, et al
    Two cell lines of t(8;21) acute myeloid leukemia with activating KIT exon 17 mutation: models for the 'second hit' hypothesis.
    Leukemia. 2008;.
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52. CHIARINI F , Del Sole M, Mongiorgi S, Gaboardi GC, et al
    The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
    Leukemia. 2008;.
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53. SO CW , van der Reijden BA
    C/EBPalpha, do not forget your TIP60.
    Leukemia. 2008;22:676-7.
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54. KONIG H , Holtz M, Modi H, Manley P, et al
    Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors.
    Leukemia. 2008;22:748-55.
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55. INOUE S , Walewska R, Dyer MJ, Cohen GM, et al
    Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells.
    Leukemia. 2008;22:819-25.
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56. SERGEEVA A , Ono Y, Rios R, Molldrem JJ, et al
    High titer autoantibodies to GM-CSF in patients with AML, CML and MDS are associated with active disease.
    Leukemia. 2008;22:783-90.
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57. ZHANG W , Konopleva M, Ruvolo VR, McQueen T, et al
    Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.
    Leukemia. 2008;22:808-18.
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58. VAN VLIERBERGHE P , Homminga I, Zuurbier L, Gladdines-Buijs J, et al
    Cooperative genetic defects in TLX3 rearranged pediatric T-ALL.
    Leukemia. 2008;22:762-70.
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59. ZANGRANDO A , Intini F, te Kronnie G, Basso G, et al
    Validation of NG2 antigen in identifying BP-ALL patients with MLL rearrangements using qualitative and quantitative flow cytometry: a prospective study.
    Leukemia. 2008;22:858-61.
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    March 2008
60. BAAK U , Gokbuget N, Orawa H, Schwartz S, et al
    Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.
    Leukemia. 2008;.
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61. FUTAMI M , Hatano T, Soda Y, Kobayashi S, et al
    RNAi-mediated silencing of p190(Bcr-Abl) inactivates Stat5 and cooperates with imatinib mesylate and 17-allylamino-17-demetoxygeldanamycin in selective killing of p190(Bcr-Abl)-expressing leukemia cells.
    Leukemia. 2008;.
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62. HUANG L , Tissing WJ, de Jonge R, van Zelst BD, et al
    Polymorphisms in folate-related genes: association with side effects of high-dose methotrexate in childhood acute lymphoblastic leukemia.
    Leukemia. 2008;.
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63. HABIB A , Hamade E, Mahfouz R, Nasrallah MS, et al
    Arsenic trioxide inhibits ATRA-induced prostaglandin E(2) and cyclooxygenase-1 in NB4 cells, a model of acute promyelocytic leukemia.
    Leukemia. 2008;.
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64. YETGIN S , Olcay L, Koc A, Germeshausen M, et al
    Transformation of severe congenital neutropenia to early acute lymphoblastic leukemia in a patient with HAX1 mutation and without G-CSF administration or receptor mutation.
    Leukemia. 2008;.
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65. SHERBENOU DW , Hantschel O, Turaga L, Kaupe I, et al
    Characterization of BCR-ABL deletion mutants from patients with chronic myeloid leukemia.
    Leukemia. 2008;.
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66. STEELMAN LS , Abrams SL, Whelan J, Bertrand FE, et al
    Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.
    Leukemia. 2008;.
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67. MCCUBREY JA , Steelman LS, Abrams SL, Bertrand FE, et al
    Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.
    Leukemia. 2008;.
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68. METZLER M , Staege MS, Harder L, Mendelova D, et al
    Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia.
    Leukemia. 2008;.
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69. BERNARDESCHI P , Fiorentini G, Dentico P, Rossi S, et al
    Fludarabine combination therapy for follicular lymphoma followed by acute myeloid leukemia: two further case records.
    Leukemia. 2008;.
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70. WHELAN JT , Ludwig DL, Bertrand FE
    HoxA9 induces insulin-like growth factor-1 receptor expression in B-lineage acute lymphoblastic leukemia.
    Leukemia. 2008;.
    PubMed     Related articles    Abstract available
    
    
    
71. HUS I , Schmitt M, Tabarkiewicz J, Radej S, et al
    Vaccination of B-CLL patients with autologous dendritic cells can change the frequency of leukemia antigen-specific CD8+ T cells as well as CD4+CD25+FoxP3+ regulatory T cells toward an antileukemia response.
    Leukemia. 2008;.
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72. LONIGRO L , Mirabile E, Munda S, Barchitta M, et al
    Association between high expression of natural killer related-genes (NCAM/CD94) and early death during induction in children with acute myeloid leukemia.
    Leukemia. 2008;.
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73. QUINTAS-CARDAMA A
    Experimental non-ATP-competitive therapies for chronic myelogenous leukemia.
    Leukemia. 2008;.
    PubMed     Related articles    Abstract available
    
    
    
74. ABECASSIS I , Maes J, Carrier JL, Hillion J, et al
    Re-expression of DNA methylation-silenced CD44 gene in a resistant NB4 cell line: rescue of CD44-dependent cell death by cAMP.
    Leukemia. 2008;22:511-20.
    PubMed     Related articles    Abstract available
    
    
    
75. GARCIA-MANERO G , Shan J, Faderl S, Cortes J, et al
    A prognostic score for patients with lower risk myelodysplastic syndrome.
    Leukemia. 2008;22:538-43.
    PubMed     Related articles    Abstract available
    
    
    
76. PATEL H , Marley SB, Greener L, Gordon MY, et al
    Subcellular distribution of p210(BCR-ABL) in CML cell lines and primary CD34+ CML cells.
    Leukemia. 2008;22:559-71.
    PubMed     Related articles    Abstract available
    
    
    
77. VAN DER VELDEN VH , Wijkhuijs JM, van Dongen JJ
    Non-specific amplification of patient-specific Ig/TCR gene rearrangements depends on the time point during therapy: implications for minimal residual disease monitoring.
    Leukemia. 2008;22:641-4.
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78. BIGGIO V , Renneville A, Nibourel O, Philippe N, et al
    Recurrent in-frame insertion in C/EBPalpha TAD2 region is a polymorphism without prognostic value in AML.
    Leukemia. 2008;22:655-7.
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79. RINGSHAUSEN I , Oelsner M, Bogner C, Peschel C, et al
    The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells.
    Leukemia. 2008;22:635-8.
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80. ESPARZA SD , Chang J, Shankar DB, Zhang B, et al
    CREB regulates Meis1 expression in normal and malignant hematopoietic cells.
    Leukemia. 2008;22:665-7.
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81. ANDERSEN RS , Wenandy L, Sorensen RB, thor Straten P, et al
    Mcl-1 and anticancer vaccination: identification of an HLA-A2-restricted epitope.
    Leukemia. 2008;22:668-9.
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82. GALIMBERTI S , Canestraro M, Khan R, Buda G, et al
    Vorinostat and bortezomib significantly inhibit WT1 gene expression in MO7-e and P39 cell lines.
    Leukemia. 2008;22:628-31.
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83. HENRICH S , Christopherson RI
    Multiple forms of nuclear p53 formed in human Raji and MEC1 cells treated with fludarabine.
    Leukemia. 2008;22:657-60.
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84. FU JF , Shi JY, Zhao WL, Li G, et al
    MassARRAY assay: a more accurate method for JAK2V617F mutation detection in Chinese patients with myeloproliferative disorders.
    Leukemia. 2008;22:660-3.
    PubMed     Related articles   
    
    
    February 2008
85. GABRIEL I , Chaidos A, Sorouri J, Dannie E, et al
    Successful peripheral blood stem cell mobilization with granulocyte colony-stimulating factor in a patient with chronic myeloid leukemia achieving a complete cytogenetic remission with dasatinib after failing imatinib.
    Leukemia. 2008;.
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86. OSTROVSKY O , Korostishevsky M, Nagler A
    Reply to 'Lack of association of the heparanase gene single-nucleotide polymorphism Arg307Lys with acute lymphoblastic leukemia in patients from Northern Ireland' by Winter et al.
    Leukemia. 2008;.
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87. CAMBIER N , Renneville A, Cazaentre T, Soenen V, et al
    JAK2V617F-positive polycythemia vera and Philadelphia chromosome-positive chronic myeloid leukemia: one patient with two distinct myeloproliferative disorders.
    Leukemia. 2008;.
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88. MAKI G , Hayes GM, Naji A, Tyler T, et al
    NK resistance of tumor cells from multiple myeloma and chronic lymphocytic leukemia patients: implication of HLA-G.
    Leukemia. 2008;.
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89. RENNEVILLE A , Roumier C, Biggio V, Nibourel O, et al
    Cooperating gene mutations in acute myeloid leukemia: a review of the literature.
    Leukemia. 2008;.
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90. PICCALUGA PP , Martinelli G, Isidori A, Malagola M, et al
    Long-term molecular complete remission with IFN-alpha in Ph+ adult acute lymphoid leukemia patients.
    Leukemia. 2008;.
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91. GU L , Zhu N, Findley HW, Zhou M, et al
    MDM2 antagonist nutlin-3 is a potent inducer of apoptosis in pediatric acute lymphoblastic leukemia cells with wild-type p53 and overexpression of MDM2.
    Leukemia. 2008;.
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92. ANDERSEN MT , Andersen MK, Christiansen DH, Pedersen-Bjergaard J, et al
    NPM1 mutations in therapy-related acute myeloid leukemia with uncharacteristic features.
    Leukemia. 2008;.
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93. SAWAYAMA Y , Miyazaki Y, Ando K, Horio K, et al
    Expression of myeloperoxidase enhances the chemosensitivity of leukemia cells through the generation of reactive oxygen species and the nitration of protein.
    Leukemia. 2008;.
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94. ALBANO F , Pannunzio A, Anelli L, Zagaria A, et al
    Genomic and molecular switching in relapsed acute promyelocytic leukemia.
    Leukemia. 2008;.
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95. DE LIMA M , Champlin RE, Thall PF, Wang X, et al
    Phase I/II study of gemtuzumab ozogamicin added to fludarabine, melphalan and allogeneic hematopoietic stem cell transplantation for high-risk CD33 positive myeloid leukemias and myelodysplastic syndrome.
    Leukemia. 2008;22:258-64.
    PubMed     Related articles    Abstract available
    
    
    
96. LU Y , Peng ZG, Yuan TT, Yin QQ, et al
    Multi-sites cleavage of leukemogenic AML1-ETO fusion protein by caspase-3 and its contribution to increased apoptotic sensitivity.
    Leukemia. 2008;22:378-86.
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97. MARTON S , Garcia MR, Robello C, Persson H, et al
    Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis.
    Leukemia. 2008;22:330-8.
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98. PATEL B , Richards SM, Rowe JM, Goldstone AH, et al
    High incidence of avascular necrosis in adolescents with acute lymphoblastic leukaemia: a UKALL XII analysis.
    Leukemia. 2008;22:308-12.
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