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The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text |
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| Leukemia |
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1 Am J Clin Pathol |
Retrieve available abstracts of this week’s articles:
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| Single Articles |
Reactivity with TdT in Merkel cell carcinoma: a potential diagnostic pitfall.
Am J Clin Pathol. 2008;129:894-8.
PubMed
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Aberrant hypomethylation of the cancer-testis antigen PRAME correlates with PRAME expression in acute myeloid leukemia.
Ann Hematol. 2008;.
PubMed
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Oral fludarabine and cyclophosphamide as front-line chemotherapy in patients with chronic lymphocytic leukemia. The impact of biological parameters in the response duration.
Ann Hematol. 2008;.
PubMed
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Abstract available
K313dup is a recurrent CEBPA mutation in de novo acute myeloid leukemia (AML).
Ann Hematol. 2008;.
PubMed
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Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.
Blood. 2008;.
PubMed
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Soluble CD22 as a tumor marker for hairy cell leukemia.
Blood. 2008;.
PubMed
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Cytotoxic T lymphocytes directed to the Preferentially Expressed Antigen of Melanoma (PRAME) target chronic myeloid leukemia.
Blood. 2008;.
PubMed
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HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells.
Blood. 2008;.
PubMed
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Development and dynamics of robust T-cell responses to CML under imatinib treatment.
Blood. 2008;111:5342-9.
PubMed
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Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
Br J Haematol. 2008;141:483-93.
PubMed
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Abstract available
t(14;19)(q32;q13) incidence and significance in B-cell lymphoproliferative disorders.
Br J Haematol. 2008;141:561-3.
PubMed
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Acute myeloid leukaemia blast cells with a tyrosine kinase domain mutation of FLT3 are less sensitive to lestaurtinib than those with a FLT3 internal tandem duplication.
Br J Haematol. 2008;141:454-60.
PubMed
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Mutated and non-mutated TP53 as targets in the treatment of leukaemia.
Br J Haematol. 2008;141:445-53.
PubMed
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Intracranial small lymphocytic lymphoma.
Br J Haematol. 2008;.
PubMed
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Epigenetic inactivation of suppressors of cytokine signalling in Philadelphia-negative chronic myeloproliferative disorders.
Br J Haematol. 2008;141:504-11.
PubMed
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Abstract available
Risk factors for leukemic transformation in patients with primary myelofibrosis.
Cancer. 2008;112:2726-32.
PubMed
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The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation.
Cancer Res. 2008;68:5198-205.
PubMed
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Resistance to TRAIL-induced apoptosis caused by constitutional phosphorylation of Akt and PTEN in acute lymphoblastic leukemia cells.
Exp Hematol. 2008;.
PubMed
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Evolutional change of karyotype with t(8;9)(p22;p24) and HLA-DR immunophenotype in relapsed acute myeloid leukemia.
Int J Hematol. 2008;.
PubMed
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Bleeding tendency in chronic neutrophilic leukemia.
Int J Hematol. 2008;.
PubMed
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Recurrent acute promyelocytic leukemia presenting as a sacral nerve root mass.
J Clin Oncol. 2008;26:3279-81.
PubMed
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Mutation of the Wilms' Tumor 1 Gene Is a Poor Prognostic Factor Associated With Chemotherapy Resistance in Normal Karyotype Acute Myeloid Leukemia: The United Kingdom Medical Research Council Adult Leukaemia Working Party.
J Clin Oncol. 2008;.
PubMed
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Low-Dose Interleukin-2 Immunotherapy Does Not Improve Outcome of Patients Age 60 Years and Older With Acute Myeloid Leukemia in First Complete Remission: Cancer and Leukemia Group B Study 9720.
J Clin Oncol. 2008;.
PubMed
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Prior treatment with the tyrosine kinase inhibitors dasatinib and nilotinib allows stem cell transplantation (SCT) in a less advanced disease phase and does not increase SCT Toxicity in patients with chronic myelogenous leukemia and philadelphia positive
Leukemia. 2008;.
PubMed
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TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis.
Leukemia. 2008;.
PubMed
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BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells.
Leukemia. 2008;.
PubMed
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Abstract available
Interleukin-4 stimulates proliferation and growth of T-cell acute lymphoblastic leukemia cells by activating mTOR signaling.
Leukemia. 2008;.
PubMed
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A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus.
Virology. 2008;.
PubMed
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Abstract available
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