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1 Biochem Pharmacol |
Retrieve available abstracts of this week’s articles:
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| Single Articles |
Triptolide, histone acetyltransferase inhibitor, suppresses growth and
chemosensitizes leukemic cells through inhibition of gene expression regulated by
TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway.
Biochem Pharmacol. 2011;82:1134-44.
PubMed
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Responses to second line tyrosine kinase inhibitors are durable: an intention to
treat analysis in chronic myeloid leukemia patients.
Blood. 2011.
PubMed
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Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells
mediated by co-culture with macrophage feeder cells.
Blood. 2011.
PubMed
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Dasatinib or imatinib in newly diagnosed chronic phase chronic myeloid leukemia:
2-year follow-up from a randomized phase 3 trial (DASISION).
Blood. 2011.
PubMed
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A small molecule screening strategy with validation on human leukemia stem cells
uncovers the therapeutic efficacy of kinetin riboside.
Blood. 2011.
PubMed
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Leukemic transformation of anaplastic large-cell lymphoma.
Blood. 2011;118:3763.
PubMed
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Concomitant occurrence of BCR-ABL and JAK2V617F mutation.
Blood. 2011;118:3445-6.
PubMed
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Key pathways as therapeutic targets.
Blood. 2011;118:2935-6.
PubMed
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Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence
through transcriptional repression of MYC.
Blood. 2011;118:4174-8.
PubMed
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Clofarabine and busulfan conditioning facilitates engraftment and provides
significant anti-tumor activity in non-remission hematologic malignancies.
Blood. 2011.
PubMed
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Type I-IFNs control GVHD and GVL responses after transplantation.
Blood. 2011;118:3399-409.
PubMed
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Targeting levels or oligomerization of nucleophosmin 1 induces differentiation
and loss of survival of human AML cells with mutant NPM1.
Blood. 2011;118:3096-106.
PubMed
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Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell
neoplasms by genomic and functional analyses.
Blood. 2011;118:3195-204.
PubMed
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PR domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cells
function.
Blood. 2011.
PubMed
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Comprehensive analysis of mammalian miRNA* species and their role in myeloid
cells.
Blood. 2011;118:3350-8.
PubMed
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Survival from childhood cancer in northern England, 1968-2005.
Br J Cancer. 2011;105:1402-8.
PubMed
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Risk of childhood acute lymphoblastic leukaemia following parental occupational
exposure to extremely low frequency electromagnetic fields.
Br J Cancer. 2011;105:1409-13.
PubMed
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Second cancer incidence and cancer mortality among chronic lymphocytic leukaemia
patients: a population-based study.
Br J Cancer. 2011;105:1076-81.
PubMed
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De Novo polycythaemia vera arising 5 years following acute myeloid leukemia
remission: suggestion of a chemotherapy resistant JAK2 clone.
Br J Haematol. 2011 Dec 8. doi: 10.1111/j.1365-2141.2011.08972.
PubMed
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Richter syndrome in chronic lymphocytic leukaemia manifesting only as tumorous
hepatomegaly.
Br J Haematol. 2011;155:135.
PubMed
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Paediatric B-cell precursor acute lymphoblastic leukaemia with t(1;19)(q23;p13):
clinical and cytogenetic characteristics of 47 cases from the Nordic countries
treated according to NOPHO protocols.
Br J Haematol. 2011;155:235-43.
PubMed
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Irreversible pan-ERBB inhibitor canertinib elicits anti-leukaemic effects and
induces the regression of FLT3-ITD transformed cells in mice.
Br J Haematol. 2011;155:198-208.
PubMed
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Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor
(G-CSF) priming for relapsed and refractory acute myeloid leukaemia.
Br J Haematol. 2011;155:182-9.
PubMed
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Constitutional trisomy 8p11.21-q11.21 mosaicism: a germline alteration
predisposing to myeloid leukaemia.
Br J Haematol. 2011;155:209-17.
PubMed
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Individualized toxicity-titrated 6-mercaptopurine increments during high-dose
methotrexate consolidation treatment of lower risk childhood acute lymphoblastic
leukaemia. A Nordic Society of Paediatric Haematology and Oncology (NOPHO) pilot
study.
Br J Haematol. 2011;155:244-7.
PubMed
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NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and
provide new insight into mechanisms of myeloid leukaemogenesis.
Br J Haematol. 2011;155:167-81.
PubMed
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Interaction potential of the endothelin-A receptor antagonist atrasentan with
drug transporters and drug-metabolising enzymes assessed in vitro.
Cancer Chemother Pharmacol. 2011;68:1093-8.
PubMed
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Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.
Cell. 2011;147:306-19.
PubMed
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Clinical efficacy of immunochemotherapy with fludarabine, epirubicin and
rituximab in the treatment for chronic lymphocytic leukaemia and prolymphocytic
leukaemia.
Eur J Haematol. 2011;87:426-33.
PubMed
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NPM1 mutation is a stable marker for minimal residual disease monitoring in acute
myeloid leukaemia patients with increased sensitivity compared to WT1 expression.
Eur J Haematol. 2011;87:400-8.
PubMed
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A patient with a 20-year lag phase between JAK2-V617F+ myeloproliferation and
NPM1-mutated AML arguing against a common origin of disease.
Eur J Haematol. 2011;87:461-3.
PubMed
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Deciphering transcriptional control mechanisms in hematopoiesis:the impact of
high-throughput sequencing technologies.
Exp Hematol. 2011;39:961-8.
PubMed
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Epstein-Barr virus-associated post-transplant lymphoproliferative disorders after
allogeneic peripheral blood stem cell transplantation for Hodgkin-like adult
T-cell leukemia/lymphoma.
Int J Hematol. 2011.
PubMed
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Posterior reversible encephalopathy syndrome in an adult patient with acute
lymphoblastic leukemia after remission induction chemotherapy.
Int J Hematol. 2011.
PubMed
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Synergistic induction of galectin-1 by CCAAT/enhancer binding protein alpha and
hypoxia-inducible factor 1alpha and its role in differentiation of acute myeloid
leukemic cells.
J Biol Chem. 2011;286:36808-19.
PubMed
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Inhibition of protein-tyrosine phosphatase 1B (PTP1B) mediates ubiquitination and
degradation of Bcr-Abl protein.
J Biol Chem. 2011;286:32313-23.
PubMed
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Familial Aggregation of Acute Myeloid Leukemia and Myelodysplastic Syndromes.
J Clin Oncol. 2011.
PubMed
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Clinical trial participation and time to treatment among adolescents and young
adults with cancer: does age at diagnosis or insurance make a difference?
J Clin Oncol. 2011;29:4045-53.
PubMed
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Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute
friend retrovirus infection but are highly cytotoxic and control virus
replication.
J Immunol. 2011;187:3730-7.
PubMed
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Sustained complete molecular response of chronic myeloid leukemia after
discontinuation of second-generation tyrosine kinase inhibitors.
Leuk Lymphoma. 2011.
PubMed
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Quality of life in chronic lymphocytic leukemia: 5-year results from the
multicenter randomized LRF CLL4 trial.
Leuk Lymphoma. 2011.
PubMed
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Hematologic improvement after flavopiridol treatment of pentostatin and rituximab
refractory hairy cell leukemia.
Leuk Lymphoma. 2011.
PubMed
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MLL-ELL fusion gene in 2 infants with acute monoblastic leukemia and myeloid
sarcoma.
Leuk Lymphoma. 2011.
PubMed
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A Phase I, Dose Escalation Study of Clofarabine in Combination with Fractionated
Gemtuzumab Ozogamicin in Patients with Refractory or Relapsed Acute Myeloid
Leukemia.
Leuk Lymphoma. 2011.
PubMed
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Targeted Therapy for Patients with Chronic Myeloid Leukemia: Clinical Trial
Experience and Challenges in Intertrial Comparisons.
Leuk Lymphoma. 2011.
PubMed
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Mitoxantrone and etoposide with or without intermediate dose cytarabine for the
treatment of primary induction failure or relapsed acute myeloid leukemia.
Leuk Res. 2011.
PubMed
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Clinical experience of bendamustine treatment for non-Hodgkin lymphoma and
chronic lymphocytic leukemia in Spain.
Leuk Res. 2011.
PubMed
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Phase I trial of sodium salicylate in patients with myelodysplastic syndromes and
acute myelogenous leukemia.
Leuk Res. 2011.
PubMed
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Abstract available
Absence of mutations in the activation loop and juxtamembrane domains of VEGFR-1
and VEGFR-2 gene in chronic myelomonocytic leukemia (CMML).
Leuk Res. 2011.
PubMed
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Role of 657del5 NBN mutation and 7p12.2 (IKZF1), 9p21 (CDKN2A), 10q21.2 (ARID5B)
and 14q11.2 (CEBPE) variation and risk of childhood ALL in the Polish population.
Leuk Res. 2011;35:1534-6.
PubMed
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Abstract available
Inhibiting HDACs in a preclinical model of HTLV-1-induced adult T-cell lymphoma.
Leuk Res. 2011;35:1436-7.
PubMed
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Diagnostic testing, treatment, cost of care, and survival among registered and
non-registered patients with myelodysplastic syndromes.
Leuk Res. 2011;35:1453-6.
PubMed
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Nilotinib therapy does not induce consistent modifications of cholesterol
metabolism resulting in clinical consequences.
Leuk Res. 2011;35:e215-6.
PubMed
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Cooperation between somatic Ikaros and Notch1 mutations at the inception of
T-ALL.
Leuk Res. 2011;35:1512-9.
PubMed
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Acquired alpha thalassemia myelodyslastic/myeloproliferative syndrome (ATMDS):
evolution on hypomethylating agent therapy.
Leuk Res. 2011;35:e203-5.
PubMed
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Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human
T-lymphotropic virus type 1 adult T cell lymphoma.
Leuk Res. 2011;35:1491-7.
PubMed
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Wilms' tumor 1-specific cytotoxic T lymphocytes can be expanded from adult donors
and cord blood.
Leuk Res. 2011;35:1520-6.
PubMed
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Disease progression mechanism in myelodysplastic syndromes: insight into the role
of the microenvironment.
Leuk Res. 2011;35:1449-52.
PubMed
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Procalcitonin is a useful marker of infection in neutropenia.
Leuk Res. 2011;35:1288-9.
PubMed
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The two faces of myeloproliferative neoplasms: Molecular events underlying
lymphoid transformation.
Leuk Res. 2011;35:1279-85.
PubMed
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Flow cytometric detection of BCR-ABL in cerebrospinal fluid.
Leuk Res. 2011;35:1286-7.
PubMed
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Validation of a scoring system to establish the probability of myelodysplastic
syndrome in patients with unexplained cytopenias or macrocytosis.
Leuk Res. 2011;35:1335-8.
PubMed
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The significance of isolated Y chromosome loss in bone marrow metaphase cells
from males over age 50 years.
Leuk Res. 2011;35:1297-300.
PubMed
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Miniaturized flow cytometry-based BCR-ABL immunoassay in detecting leptomeningeal
disease.
Leuk Res. 2011;35:1290-3.
PubMed
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Mast-cell leukemia exome sequencing reveals a mutation in the IgE mast-cell
receptor beta chain and KIT V654A.
Leukemia. 2011 Dec 16. doi: 10.1038/leu.2011.
PubMed
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RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute
leukemia cells to chemotherapy-induced apoptosis.
Leukemia. 2011 Dec 16. doi: 10.1038/leu.2011.
PubMed
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Digital gene expression profiling of primary acute lymphoblastic leukemia cells.
Leukemia. 2011 Dec 16. doi: 10.1038/leu.2011.
PubMed
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Wnt signaling strength regulates normal hematopoiesis and its deregulation is
involved in leukemia development.
Leukemia. 2011 Dec 15. doi: 10.1038/leu.2011.
PubMed
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Abstract available
In vivo expression of an aberrant MYB-GATA1 fusion induces leukemia in the
presence of GATA1 reduced levels.
Leukemia. 2011;25:1922.
PubMed
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Long-term WT1 peptide vaccination for patients with acute myeloid leukemia with
minimal residual disease.
Leukemia. 2011 Dec 13. doi: 10.1038/leu.2011.
PubMed
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Dysregulation of TNFalpha-induced necroptotic signaling in chronic lymphocytic
leukemia: suppression of CYLD gene by LEF1.
Leukemia. 2011 Dec 13. doi: 10.1038/leu.2011.
PubMed
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Nilotinib is effective in imatinib-resistant or -intolerant patients with chronic
myeloid leukemia in blastic phase.
Leukemia. 2011 Dec 13. doi: 10.1038/leu.2011.
PubMed
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Prognostic factors for acute myeloid leukemia patients with t(6;9)(p23;q34) who
underwent an allogeneic hematopoietic stem cell transplant.
Leukemia. 2011 Dec 9. doi: 10.1038/leu.2011.
PubMed
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Residual normal stem cells can be detected in newly diagnosed chronic myeloid
leukemia patients by a new flow cytometric approach and predict for optimal
response to imatinib.
Leukemia. 2011 Dec 9. doi: 10.1038/leu.2011.
PubMed
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Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated
with dasatinib is associated with cytomegalovirus reactivation.
Leukemia. 2011;25:1587-97.
PubMed
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Abstract available
Redundancy and specificity of the metalloprotease system mediating oncogenic
NOTCH1 activation in T-ALL.
Leukemia. 2011;25:1564-9.
PubMed
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SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia.
N Engl J Med. 2011.
PubMed
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Chimeric antigen receptor-modified T cells in CLL.
N Engl J Med. 2011;365:1937-8.
PubMed
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Chimeric antigen receptor-modified T cells in CLL.
N Engl J Med. 2011;365:1937.
PubMed
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Inducible apoptosis as a safety switch for adoptive cell therapy.
N Engl J Med. 2011;365:1673-83.
PubMed
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High-throughput VDJ sequencing for quantification of minimal residual disease in
chronic lymphocytic leukemia and immune reconstitution assessment.
Proc Natl Acad Sci U S A. 2011.
PubMed
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Targeting MYC dependence in cancer by inhibiting BET bromodomains.
Proc Natl Acad Sci U S A. 2011;108:16669-74.
PubMed
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