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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in Exp Hematol

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Single Articles


    July 2008
  1. DIDA F , Li Y, Iwao A, Deguchi T, et al
    Resistance to TRAIL-induced apoptosis caused by constitutional phosphorylation of Akt and PTEN in acute lymphoblastic leukemia cells.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


    June 2008
  2. LU S , Chen Z, Yang J, Chen L, et al
    Overexpression of the PSMB5 gene contributes to bortezomib resistance in T-lymphoblastic lymphoma/leukemia cells derived from Jurkat line.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


  3. SUBBIAH V , Viny AD, Rosenblatt S, Pohlman B, et al
    Outcomes of splenectomy in T-cell large granular lymphocyte leukemia with splenomegaly and cytopenia.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


    April 2008
  4. MATSUMOTO K , Murao K, Imachi H, Nishiuchi T, et al
    The role of calcium/calmodulin-dependent protein kinase cascade on MIP-1alpha gene expression of ATL cells.
    Exp Hematol. 2008;36:390-400.
    PubMed     Related articles    Abstract available


    March 2008
  5. HIROUCHI T , Takabatake T, Yoshida K, Nitta Y, et al
    Upregulation of c-myc gene accompanied by PU.1 deficiency in radiation-induced acute myeloid leukemia in mice.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


  6. GIJZEN K , Raymakers RA, Broers KM, Figdor CG, et al
    Interaction of acute lymphopblastic leukemia cells with C-type lectins DC-SIGN and L-SIGN.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  7. WOLFF L , Ackerman SJ, Nucifora G
    Meeting report: Seventh International Workshop on Molecular Aspects of Myeloid Stem Cell Development and Leukemia, Annapolis, MD, May 13-16, 2007.
    Exp Hematol. 2008;.
    PubMed     Related articles   


  8. DISTLER E , Wolfel C, Kohler S, Nonn M, et al
    Acute myeloid leukemia (AML)-reactive cytotoxic T lymphocyte clones rapidly expanded from CD8(+) CD62L((high)+) T cells of healthy donors prevent AML engraftment in NOD/SCID IL2Rgamma(null) mice.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


  9. SCHULZE A , Schirutschke H, Oelschlagel U, Schmitz M, et al
    Altered phenotype of natural killer cell subsets after haploidentical stem cell transplantation.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


  10. CHOW JM , Liu CR, Lin CP, Lee CN, et al
    Downregulation of c-Myc determines sensitivity to 2-methoxyestradiol-induced apoptosis in human acute myeloid leukemia.
    Exp Hematol. 2008;36:140-8.
    PubMed     Related articles    Abstract available


    January 2008
  11. ZHONG RK , Lane TA, Ball ED
    Generation of T-cell lines to autologous acute myeloid leukemia cells by competitive limiting dilution culture of acute myeloid leukemia mononuclear cells.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


  12. HO MM , Hogge DE, Ling V
    MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


  13. ROYER PJ , Bougras G, Ebstein F, Leveque L, et al
    Efficient monocyte-derived dendritic cell generation in patients with acute myeloid leukemia after chemotherapy treatment: Application to active immunotherapy.
    Exp Hematol. 2008;.
    PubMed     Related articles    Abstract available


  14. NAKATA Y , Kondoh K, Fukushima S, Hashiguchi A, et al
    Mutated D4-guanine diphosphate-dissociation inhibitor is found in human leukemic cells and promotes leukemic cell invasion.
    Exp Hematol. 2008;36:37-50.
    PubMed     Related articles    Abstract available


    November 2007
  15. NAGAI S , Ichikawa M, Takahashi T, Sato H, et al
    The origin of neoplastic mast cells in systemic mastocytosis with AML1/ETO-positive acute myeloid leukemia.
    Exp Hematol. 2007;35:1747-1752.
    PubMed     Related articles    Abstract available


  16. NAJFELD V , Cozza A, Berkofsy-Fessler W, Prchal J, et al
    Numerical gain and structural rearrangements of JAK2, identified by FISH, characterize both JAK2617V>F-positive and -negative patients with Ph-negative MPD, myelodysplasia, and B-lymphoid neoplasms.
    Exp Hematol. 2007;35:1668-76.
    PubMed     Related articles    Abstract available


    October 2007
  17. CHAMPELOVIER P , El Atifi M, Pautre V, Rostaing B, et al
    Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors.
    Exp Hematol. 2007;.
    PubMed     Related articles    Abstract available


  18. CONNELLY-SMITH L , Pattinson J, Grundy M, Shang S, et al
    P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors.
    Exp Hematol. 2007;.
    PubMed     Related articles    Abstract available


  19. MICHELFELDER S , Lee MK, Delima-Hahn E, Wilmes T, et al
    Vectors selected from adeno-associated viral display peptide libraries for leukemia cell-targeted cytotoxic gene therapy.
    Exp Hematol. 2007;.
    PubMed     Related articles    Abstract available


  20. VAN GOSLIGA D , Schepers H, Rizo A, van der Kolk D, et al
    Establishing long-term cultures with self-renewing acute myeloid leukemia stem/progenitor cells.
    Exp Hematol. 2007;35:1538-49.
    PubMed     Related articles    Abstract available


  21. KANCHA RK , Grundler R, Peschel C, Duyster J, et al
    Sensitivity toward sorafenib and sunitinib varies between different activating and drug-resistant FLT3-ITD mutations.
    Exp Hematol. 2007;35:1522-6.
    PubMed     Related articles    Abstract available


    September 2007
  22. MARIN V , Kakuda H, Dander E, Imai C, et al
    Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BB-zeta activating signal.
    Exp Hematol. 2007;35:1388-97.
    PubMed     Related articles    Abstract available   Free Full Text


    August 2007
  23. GRAND FH , Iqbal S, Zhang L, Russell NH, et al
    A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy.
    Exp Hematol. 2007;.
    PubMed     Related articles    Abstract available


  24. LAGNEAUX L , Gillet N, Stamatopoulos B, Delforge A, et al
    Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response.
    Exp Hematol. 2007;.
    PubMed     Related articles    Abstract available


  25. AISAKI K , Aizawa S, Fujii H, Kanno J, et al
    Glycolytic inhibition by mutation of pyruvate kinase gene increases oxidative stress and causes apoptosis of a pyruvate kinase deficient cell line.
    Exp Hematol. 2007;35:1190-200.
    PubMed     Related articles    Abstract available


  26. XU M , Li D, Lu Y, Chen GQ, et al
    Leukemogenic AML1-ETO fusion protein increases carcinogen-DNA adduct formation with upregulated expression of cytochrome P450-1A1 gene.
    Exp Hematol. 2007;35:1249-55.
    PubMed     Related articles    Abstract available


    July 2007
  27. TAKAHASHI H , Furukawa T, Yano T, Sato N, et al
    Identification of an overexpressed gene, HSPA4L, the product of which can provoke prevalent humoral immune responses in leukemia patients.
    Exp Hematol. 2007;35:1091-9.
    PubMed     Related articles    Abstract available


  28. OLIVIERI A , Capelli D, Troiani E, Poloni A, et al
    A new intensive induction schedule, including high-dose Idarubicin, high-dose Aracytin and Amifostine, in older AML patients: feasibility and long-term results in 42 patients.
    Exp Hematol. 2007;35:1074-82.
    PubMed     Related articles    Abstract available


    June 2007
  29. OKUMURA AJ , Peterson LF, Lo MC, Zhang DE, et al
    Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.
    Exp Hematol. 2007;35:978-88.
    PubMed     Related articles    Abstract available


  30. BUND D , Mayr C, Kofler DM, Hallek M, et al
    CD23 is recognized as tumor-associated antigen (TAA) in B-CLL by CD8+ autologous T lymphocytes.
    Exp Hematol. 2007;35:920-30.
    PubMed     Related articles    Abstract available


  31. SHEN S , Passioura T, Symonds G, Dolnikov A, et al
    N-ras oncogene-induced gene expression in human hematopoietic progenitor cells: upregulation of p16INK4a and p21CIP1/WAF1 correlates with myeloid differentiation.
    Exp Hematol. 2007;35:908-19.
    PubMed     Related articles    Abstract available


    May 2007
  32. KORNBLAU SM , Aycox PG, Stephens C, McCue LD, et al
    Control of graft-versus-host disease with maintenance of the graft-versus-leukemia effect in a murine allogeneic transplant model using retrovirally transduced murine suicidal lymphocytes.
    Exp Hematol. 2007;35:842-53.
    PubMed     Related articles    Abstract available


  33. ROZENVELD-GEUGIEN M , Baas IO, van Gosliga D, Vellenga E, et al
    Expansion of normal and leukemic human hematopoietic stem/progenitor cells requires rac-mediated interaction with stromal cells.
    Exp Hematol. 2007;35:782-92.
    PubMed     Related articles    Abstract available


    April 2007
  34. STONE RM
    Novel therapeutic agents in acute myeloid leukemia.
    Exp Hematol. 2007;35.
    PubMed     Related articles    Abstract available


  35. DEININGER MW
    Optimizing therapy of chronic myeloid leukemia.
    Exp Hematol. 2007;35.
    PubMed     Related articles    Abstract available


  36. RAI KR
    Pathophysiologic mechanisms of chronic lymphocytic leukemia and their application to therapy.
    Exp Hematol. 2007;35.
    PubMed     Related articles   


  37. GERY S , Park DJ, Vuong PT, Virk RK, et al
    RTP801 is a novel retinoic acid-responsive gene associated with myeloid differentiation.
    Exp Hematol. 2007;35:572-8.
    PubMed     Related articles    Abstract available


  38. SHADDUCK RK , Latsko JM, Rossetti JM, Haq B, et al
    Recent advances in myelodysplastic syndromes.
    Exp Hematol. 2007;35.
    PubMed     Related articles    Abstract available


  39. HIRABAYASHI Y , Inoue T
    Implications of hemopoietic progenitor cell kinetics and experimental leukemogenesis: Relevance to Gompertzean mortality as possible hematotoxicological endpoint.
    Exp Hematol. 2007;35.
    PubMed     Related articles    Abstract available


  40. RITHIDECH KN , Honikel L, Simon SR
    Radiation leukemogenesis: a proteomic approach.
    Exp Hematol. 2007;35.
    PubMed     Related articles    Abstract available


  41. MOORE MA , Dorn DC, Schuringa JJ, Chung KY, et al
    Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cells.
    Exp Hematol. 2007;35.
    PubMed     Related articles    Abstract available


    March 2007
  42. KATO K , Chu P, Takahashi S, Hamada H, et al
    Metalloprotease inhibitors block release of soluble CD27 and enhance the immune stimulatory activity of chronic lymphocytic leukemia cells.
    Exp Hematol. 2007;35:434-42.
    PubMed     Related articles    Abstract available


    February 2007
  43. KOKHAEI P , Palma M, Hansson L, Osterborg A, et al
    Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells.
    Exp Hematol. 2007;35:297-304.
    PubMed     Related articles    Abstract available


  44. SCOTT SA , Lakshimikuttysamma A, Sheridan DP, Sanche SE, et al
    Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression.
    Exp Hematol. 2007;35:263-73.
    PubMed     Related articles    Abstract available


  45. BLAU O , Hofmann WK, Baldus CD, Thiel G, et al
    Chromosomal aberrations in bone marrow mesenchymal stroma cells from patients with myelodysplastic syndrome and acute myeloblastic leukemia.
    Exp Hematol. 2007;35:221-9.
    PubMed     Related articles    Abstract available


  46. PETRAK J , Myslivcova D, Man P, Cmejlova J, et al
    Proteomic analysis of erythroid differentiation induced by hexamethylene bisacetamide in murine erythroleukemia cells.
    Exp Hematol. 2007;35:193-202.
    PubMed     Related articles    Abstract available


    January 2007
  47. SHEN J , Tai YC, Zhou J, Stephen Wong CH, et al
    Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling.
    Exp Hematol. 2007;35:75-83.
    PubMed     Related articles    Abstract available


  48. THOMPSON JE , Conlon JP, Yang X, Sanchez PV, et al
    Enhanced growth of myelodysplastic colonies in hypoxic conditions.
    Exp Hematol. 2007;35:21-31.
    PubMed     Related articles    Abstract available


    December 2006
  49. SCHMITT M , Li L, Giannopoulos K, Chen J, et al
    Chronic myeloid leukemia cells express tumor-associated antigens eliciting specific CD8+ T-cell responses and are lacking costimulatory molecules.
    Exp Hematol. 2006;34:1709-19.
    PubMed     Related articles    Abstract available


  50. CAMPAS C , Cosialls AM, Barragan M, Iglesias-Serret D, et al
    Bcl-2 inhibitors induce apoptosis in chronic lymphocytic leukemia cells.
    Exp Hematol. 2006;34:1663-9.
    PubMed     Related articles    Abstract available


    November 2006
  51. KAWAHARA M , Hori T, Matsubara Y, Okawa K, et al
    Identification of HLA class I-restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis.
    Exp Hematol. 2006;34:1496-504.
    PubMed     Related articles    Abstract available


  52. HUANG MJ , Cheng YC, Liu CR, Lin S, et al
    A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia.
    Exp Hematol. 2006;34:1480-9.
    PubMed     Related articles    Abstract available


  53. GIOTOPOULOS G , McCormick C, Cole C, Zanker A, et al
    DNA methylation during mouse hemopoietic differentiation and radiation-induced leukemia.
    Exp Hematol. 2006;34:1462-70.
    PubMed     Related articles    Abstract available


    October 2006
  54. WEIGEL BJ , Panoskaltsis-Mortari A, Diers M, Garcia M, et al
    Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses.
    Exp Hematol. 2006;34:1403-12.
    PubMed     Related articles    Abstract available


    September 2006
  55. SAITO TI , Rubio MT, Sykes M
    Clinical relevance of recipient leukocyte infusion as antitumor therapy following nonmyeloablative allogeneic hematopoietic cell transplantation.
    Exp Hematol. 2006;34:1271-7.
    PubMed     Related articles    Abstract available


  56. CHAN RJ , Li Y, Hass MN, Walter A, et al
    Shp-2 heterozygous hematopoietic stem cells have deficient repopulating ability due to diminished self-renewal.
    Exp Hematol. 2006;34:1229-1238.
    PubMed     Related articles    Abstract available


  57. MARIN V , Dander E, Biagi E, Introna M, et al
    Characterization of in vitro migratory properties of anti-CD19 chimeric receptor-redirected CIK cells for their potential use in B-ALL immunotherapy.
    Exp Hematol. 2006;34:1219-29.
    PubMed     Related articles    Abstract available


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