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Leukemia

Free Subscription Articles published in Cancer Res Retrieve available abstracts of 74 articles: HTML format Text format

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March 2010
1. JIN Y , Lu Z, Ding K, Li J, et al
   Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-{kappa}B Pathway and Generation of Reactive Oxygen Species.
   Cancer Res. 2010.
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2. ZHANG W , Konopleva M, Burks JK, Dywer KC, et al
   Blockade of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase and Murine Double Minute Synergistically Induces Apoptosis in Acute Myeloid Leukemia via BH3-Only Proteins Puma and Bim.
   Cancer Res. 2010.
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   February 2010
3. GLEIXNER KV , Ferenc V, Peter B, Gruze A, et al
   Polo-like Kinase 1 (Plk1) as a Novel Drug Target in Chronic Myeloid Leukemia: Overriding Imatinib Resistance with the Plk1 Inhibitor BI 2536.
   Cancer Res. 2010.
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4. MARINA O , Hainz U, Biernacki MA, Zhang W, et al
   Serologic Markers of Effective Tumor Immunity against Chronic Lymphocytic Leukemia Include Nonmutated B-Cell Antigens.
   Cancer Res. 2010.
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   January 2010
5. PUISSANT A , Robert G, Fenouille N, Luciano F, et al
   Resveratrol Promotes Autophagic Cell Death in Chronic Myelogenous Leukemia Cells via JNK-Mediated p62/SQSTM1 Expression and AMPK Activation.
   Cancer Res. 2010.
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6. BIERNACKI MA , Marina O, Zhang W, Liu F, et al
   Efficacious Immune Therapy in Chronic Myelogenous Leukemia (CML) Recognizes Antigens That Are Expressed on CML Progenitor Cells.
   Cancer Res. 2010.
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7. ABDEL-WAHAB O , Manshouri T, Patel J, Harris K, et al
   Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias.
   Cancer Res. 2010;70:447-52.
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8. KOOL J , Uren AG, Martins CP, Sie D, et al
   Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
   Cancer Res. 2010;70:520-31.
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   November 2009
9. LOEDER S , Zenz T, Schnaiter A, Mertens D, et al
   A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic Leukemia.
   Cancer Res. 2009.
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   October 2009
10. CAVELIER C , Didier C, Prade N, Mansat-De Mas V, et al
    Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy.
    Cancer Res. 2009.
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11. COLLIER LS , Adams DJ, Hackett CS, Bendzick LE, et al
    Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality.
    Cancer Res. 2009.
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12. MCELLIGOTT AM , Maginn EN, Greene LM, McGuckin S, et al
    The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia.
    Cancer Res. 2009.
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13. JAETAO JE , Butler KS, Adolphi NL, Lovato DM, et al
    Enhanced Leukemia Cell Detection Using a Novel Magnetic Needle and Nanoparticles.
    Cancer Res. 2009.
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14. WAHNER HENDRICKSON AE , Haluska P, Schneider PA, Loegering DA, et al
    Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro.
    Cancer Res. 2009;69:7635-43.
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    September 2009
15. BEHAN JW , Yun JP, Proektor MP, Ehsanipour EA, et al
    Adipocytes Impair Leukemia Treatment in Mice.
    Cancer Res. 2009.
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    August 2009
16. VLAD A , Deglesne PA, Letestu R, Saint-Georges S, et al
    Down-regulation of CXCR4 and CD62L in Chronic Lymphocytic Leukemia Cells Is Triggered by B-Cell Receptor Ligation and Associated with Progressive Disease.
    Cancer Res. 2009.
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17. JAGANI Z , Song K, Kutok JL, Dewar MR, et al
    Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL-Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors.
    Cancer Res. 2009.
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    July 2009
18. RACANELLI AC , Rothbart SB, Heyer CL, Moran RG, et al
    Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition.
    Cancer Res. 2009;69:5467-74.
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19. ZHANG KH , Tian HY, Gao X, Lei WW, et al
    Ferritin heavy chain-mediated iron homeostasis and subsequent increased reactive oxygen species production are essential for epithelial-mesenchymal transition.
    Cancer Res. 2009;69:5340-8.
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    June 2009
20. BUCHNER M , Fuchs S, Prinz G, Pfeifer D, et al
    Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia.
    Cancer Res. 2009.
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21. JOHNSON GG , Sherrington PD, Carter A, Lin K, et al
    A Novel Type of p53 Pathway Dysfunction in Chronic Lymphocytic Leukemia Resulting from Two Interacting Single Nucleotide Polymorphisms within the p21 Gene.
    Cancer Res. 2009.
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22. HAUPT S , di Agostino S, Mizrahi I, Alsheich-Bartok O, et al
    Promyelocytic leukemia protein is required for gain of function by mutant p53.
    Cancer Res. 2009;69:4818-26.
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23. APPERT A , Nam CH, Lobato N, Priego E, et al
    Targeting LMO2 with a peptide aptamer establishes a necessary function in overt T-cell neoplasia.
    Cancer Res. 2009;69:4784-90.
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24. DAVIES NJ , Hayden RE, Simpson PJ, Birtwistle J, et al
    AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.
    Cancer Res. 2009;69:4769-75.
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25. SALEK-ARDAKANI S , Smooha G, de Boer J, Sebire NJ, et al
    ERG is a megakaryocytic oncogene.
    Cancer Res. 2009;69:4665-73.
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    May 2009
26. KOMAROVA NL , Wodarz D
    Combination Therapies against Chronic Myeloid Leukemia: Short-term versus Long-term Strategies.
    Cancer Res. 2009.
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27. AGIRRE X , Vilas-Zornoza A, Jimenez-Velasco A, Ignacio Martin-Subero J, et al
    Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia.
    Cancer Res. 2009.
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28. FUJISAKI H , Kakuda H, Shimasaki N, Imai C, et al
    Expansion of highly cytotoxic human natural killer cells for cancer cell therapy.
    Cancer Res. 2009;69:4010-7.
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29. KUROSU T , Ohki M, Wu N, Kagechika H, et al
    Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway.
    Cancer Res. 2009;69:3927-36.
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30. HODGE DL , Yang J, Buschman MD, Schaughency PM, et al
    Interleukin-15 enhances proteasomal degradation of bid in normal lymphocytes: implications for large granular lymphocyte leukemias.
    Cancer Res. 2009;69:3986-94.
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    April 2009
31. FADERL S , Pal A, Bornmann W, Albitar M, et al
    Kit Inhibitor APcK110 Induces Apoptosis and Inhibits Proliferation of Acute Myeloid Leukemia Cells.
    Cancer Res. 2009.
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32. ZUCCHETTO A , Benedetti D, Tripodo C, Bomben R, et al
    CD38/CD31, the CCL3 and CCL4 Chemokines, and CD49d/Vascular Cell Adhesion Molecule-1 Are Interchained by Sequential Events Sustaining Chronic Lymphocytic Leukemia Cell Survival.
    Cancer Res. 2009.
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33. LOU YJ , Pan XR, Jia PM, Li D, et al
    IFR-9/STAT2 functional interaction drives retinoic acid-induced gene G expression independently of STAT1.
    Cancer Res. 2009;69:3673-80.
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34. OKE A , Pearce D, Wilkinson RW, Crafter C, et al
    AZD1152 Rapidly and Negatively Affects the Growth and Survival of Human Acute Myeloid Leukemia Cells In vitro and In vivo.
    Cancer Res. 2009.
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35. CHIARINI F , Fala F, Tazzari PL, Ricci F, et al
    Dual Inhibition of Class IA Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin as a New Therapeutic Option for T-Cell Acute Lymphoblastic Leukemia.
    Cancer Res. 2009.
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36. LAVALLARD VJ , Pradelli LA, Paul A, Beneteau M, et al
    Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells.
    Cancer Res. 2009;69:3013-20.
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    March 2009
37. RAO SS , O'Neil J, Liberator CD, Hardwick JS, et al
    Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells.
    Cancer Res. 2009.
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38. HARTMANN TN , Grabovsky V, Wang W, Desch P, et al
    Circulating B-Cell Chronic Lymphocytic Leukemia Cells Display Impaired Migration to Lymph Nodes and Bone Marrow.
    Cancer Res. 2009.
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39. PIGAZZI M , Manara E, Baron E, Basso G, et al
    miR-34b Targets Cyclic AMP-Responsive Element Binding Protein in Acute Myeloid Leukemia.
    Cancer Res. 2009.
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    February 2009
40. INDRACCOLO S , Minuzzo S, Masiero M, Pusceddu I, et al
    Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy.
    Cancer Res. 2009;69:1314-23.
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41. HAMBLEY TW , Hait WN
    Is anticancer drug development heading in the right direction?
    Cancer Res. 2009;69:1259-62.
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42. BILLOTTET C , Banerjee L, Vanhaesebroeck B, Khwaja A, et al
    Inhibition of Class I Phosphoinositide 3-Kinase Activity Impairs Proliferation and Triggers Apoptosis in Acute Promyelocytic Leukemia without Affecting Atra-Induced Differentiation.
    Cancer Res. 2009;69:1027-36.
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43. LI Z , Luo RT, Mi S, Sun M, et al
    Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias.
    Cancer Res. 2009;69:1109-16.
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    January 2009
44. GIANNI' M , Boldetti A, Guarnaccia V, Rambaldi A, et al
    Inhibition of the Peptidyl-Prolyl-Isomerase Pin1 Enhances the Responses of Acute Myeloid Leukemia Cells to Retinoic Acid via Stabilization of RAR{alpha} and PML-RAR{alpha}
    Cancer Res. 2009.
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45. BAESSLER T , Krusch M, Schmiedel BJ, Kloss M, et al
    Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Protein Ligand Subverts Immunosurveillance of Acute Myeloid Leukemia in Humans.
    Cancer Res. 2009.
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46. HERZER K , Hofmann TG, Teufel A, Schimanski CC, et al
    IFN-{alpha}-Induced Apoptosis in Hepatocellular Carcinoma Involves Promyelocytic Leukemia Protein and TRAIL Independently of p53.
    Cancer Res. 2009.
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47. PAGEL JM , Matthews DC, Kenoyer A, Hamlin DK, et al
    Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid leukemia.
    Cancer Res. 2009;69:185-92.
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48. LAURENZANA A , Petruccelli LA, Pettersson F, Figueroa ME, et al
    Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells.
    Cancer Res. 2009;69:55-64.
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49. WIENECKE A , Bacher G
    Indibulin, a novel microtubule inhibitor, discriminates between mature neuronal and nonneuronal tubulin.
    Cancer Res. 2009;69:171-7.
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    December 2008
50. ENJUANES A , Benavente Y, Bosch F, Martin-Guerrero I, et al
    Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.
    Cancer Res. 2008;68:10178-86.
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51. VAN GENT R , Kater AP, Otto SA, Jaspers A, et al
    In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow.
    Cancer Res. 2008;68:10137-44.
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52. HARPER DP , Aplan PD
    Chromosomal rearrangements leading to MLL gene fusions: clinical and biological aspects.
    Cancer Res. 2008;68:10024-7.
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53. ASHWORTH A
    Drug resistance caused by reversion mutation.
    Cancer Res. 2008;68:10021-3.
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54. SPARDY N , Duensing A, Hoskins EE, Wells SI, et al
    HPV-16 E7 Reveals a Link between DNA Replication Stress, Fanconi Anemia D2 Protein, and Alternative Lengthening of Telomere-Associated Promyelocytic Leukemia Bodies.
    Cancer Res. 2008;68:9954-63.
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55. WIEMELS JL , Hofmann J, Kang M, Selzer R, et al
    Chromosome 12p Deletions in TEL-AML1 Childhood Acute Lymphoblastic Leukemia Are Associated with Retrotransposon Elements and Occur Postnatally.
    Cancer Res. 2008;68:9935-44.
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56. KOVAR M , Tomala J, Chmelova H, Kovar L, et al
    Overcoming Immunoescape Mechanisms of BCL1 Leukemia and Induction of CD8+ T-Cell-Mediated BCL1-Specific Resistance in Mice Cured by Targeted Polymer-Bound Doxorubicin.
    Cancer Res. 2008;68:9875-83.
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57. KONIG H , Copland M, Chu S, Jove R, et al
    Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells.
    Cancer Res. 2008;68:9624-33.
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58. BARRET JM , Kruczynski A, Vispe S, Annereau JP, et al
    F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.
    Cancer Res. 2008;68:9845-53.
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59. MAHON FX , Hayette S, Lagarde V, Belloc F, et al
    Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression.
    Cancer Res. 2008;68:9809-16.
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    November 2008
60. TAZZARI PL , Tabellini G, Ricci F, Papa V, et al
    Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
    Cancer Res. 2008;68:9394-403.
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61. LINK PA , Baer MR, James SR, Jones DA, et al
    p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia.
    Cancer Res. 2008;68:9358-66.
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62. SHEN M , Yen A
    c-Cbl Interacts with CD38 and Promotes Retinoic Acid-Induced Differentiation and G0 Arrest of Human Myeloblastic Leukemia Cells.
    Cancer Res. 2008;68:8761-9.
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63. VOLPATO CB , Martinez-Alfaro M, Corvi R, Gabus C, et al
    Enhanced sensitivity of the RET proto-oncogene to ionizing radiation in vitro.
    Cancer Res. 2008;68:8986-92.
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64. YEUNG ML , Yasunaga J, Bennasser Y, Dusetti N, et al
    Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1.
    Cancer Res. 2008;68:8976-85.
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    October 2008
65. TILL KJ , Harris RJ, Linford A, Spiller DG, et al
    Cell motility in chronic lymphocytic leukemia: defective Rap1 and alphaLbeta2 activation by chemokine.
    Cancer Res. 2008;68:8429-36.
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66. HORTON HM , Bernett MJ, Pong E, Peipp M, et al
    Potent in vitro and in vivo activity of an Fc-engineered anti-CD19 monoclonal antibody against lymphoma and leukemia.
    Cancer Res. 2008;68:8049-57.
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67. EWALD B , Sampath D, Plunkett W
    ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
    Cancer Res. 2008;68:7947-55.
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    September 2008
68. MANKAI A , Bordron A, Renaudineau Y, Martins-Carvalho C, et al
    Purine-rich box-1-mediated reduced expression of CD20 alters rituximab-induced lysis of chronic lymphocytic leukemia B cells.
    Cancer Res. 2008;68:7512-9.
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    August 2008
69. CASE M , Matheson E, Minto L, Hassan R, et al
    Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia.
    Cancer Res. 2008;68:6803-9.
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70. LIBY K , Yore MM, Roebuck BD, Baumgartner KJ, et al
    A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
    Cancer Res. 2008;68:6727-33.
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71. DING Q , Huo L, Yang JY, Xia W, et al
    Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer.
    Cancer Res. 2008;68:6109-17.
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72. FRIESEN C , Roscher M, Alt A, Miltner E, et al
    Methadone, commonly used as maintenance medication for outpatient treatment of opioid dependence, kills leukemia cells and overcomes chemoresistance.
    Cancer Res. 2008;68:6059-64.
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    July 2008
73. KRISHNAMURTHY P , Schwab M, Takenaka K, Nachagari D, et al
    Transporter-mediated protection against thiopurine-induced hematopoietic toxicity.
    Cancer Res. 2008;68:4983-9.
    PubMed     Text format     Related articles    Abstract available
    
    
    June 2008
74. YUAN ZR , Shi Y
    Chloramphenicol induces abnormal differentiation and inhibits apoptosis in activated T cells.
    Cancer Res. 2008;68:4875-81.
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