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Leukemia

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November 2011
1. MEYER LH , Debatin KM
   Diversity of Human Leukemia Xenograft Mouse Models: Implications for Disease Biology.
   Cancer Res. 2011.
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   September 2011
2. PATTERSON AD , Maurhofer O, Beyoglu D, Lanz C, et al
   Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling.
   Cancer Res. 2011.
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3. PRITCHARD JR , Gilbert LA, Meacham CE, Ricks JL, et al
   Bcl-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response.
   Cancer Res. 2011;71:5850-8.
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   August 2011
4. NUNES CT , Miners KL, Dolton G, Pepper C, et al
   A novel tumor antigen derived from enhanced degradation of bax protein in human cancers.
   Cancer Res. 2011;71:5435-44.
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5. GOCEK E , Wang X, Liu X, Liu CG, et al
   MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis.
   Cancer Res. 2011.
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   July 2011
6. OUSSENKO IA , Holland JF, Reddy EP, Ohnuma T, et al
   Effect of ON 01910.Na, an anticancer mitotic inhibitor, on cell-cycle progression correlates with RanGAP1 hyperphosphorylation.
   Cancer Res. 2011;71:4968-76.
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7. FUCIKOVA J , Kralikova P, Fialova A, Brtnicky T, et al
   Human tumor cells killed by anthracyclines induce a tumor-specific immune response.
   Cancer Res. 2011;71:4821-33.
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8. PARMAR A , Marz S, Rushton S, Holzwarth C, et al
   Stromal niche cells protect early leukemic FLT3-ITD+ progenitor cells against first-generation FLT3 tyrosine kinase inhibitors.
   Cancer Res. 2011;71:4696-706.
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   June 2011
9. VIRGILI A , Koptyra M, Dasgupta Y, Glodkowska-Mrowka E, et al
   Imatinib sensitivity in BCR-ABL1-positive chronic myeloid leukemia cells is regulated by the remaining normal ABL1 allele.
   Cancer Res. 2011.
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10. KVINLAUG BT , Chan WI, Bullinger L, Ramaswami M, et al
    Common and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemias.
    Cancer Res. 2011;71:4117-29.
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11. NORDE WJ , Maas F, Hobo W, Korman A, et al
    PD-1/PD-L1 interactions contribute to functional T cell impairment in patients that relapse with cancer after allogeneic stem cell transplantation.
    Cancer Res. 2011.
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    May 2011
12. SILVA A , Laranjeira AB, Martins LR, Cardoso BA, et al
    IL-7 contributes to human T-cell acute lymphoblastic leukemia progression in vivo.
    Cancer Res. 2011.
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13. AUDRITO V , Vaisitti T, Rossi D, Gottardi D, et al
    Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network.
    Cancer Res. 2011.
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    April 2011
14. EIDE CA , Adrian LT, Tyner JW, Mac Partlin M, et al
    The ABL Switch Control Inhibitor DCC-2036 Is Active against the Chronic Myeloid Leukemia Mutant BCR-ABLT315I and Exhibits a Narrow Resistance Profile.
    Cancer Res. 2011.
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15. ELLWOOD-YEN K , Keilhack H, Kunii K, Dolinski B, et al
    PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.
    Cancer Res. 2011;71:3052-65.
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16. SACHS RK , Johnsson K, Hahnfeldt P, Luo J, et al
    A Multicellular Basis for the Origination of Blast Crisis in Chronic Myeloid Leukemia.
    Cancer Res. 2011.
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17. HU X , Yang D, Zimmerman M, Liu F, et al
    IRF8 Regulates Acid Ceramidase Expression to Mediate Apoptosis and Suppresses Myelogeneous Leukemia.
    Cancer Res. 2011.
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    March 2011
18. TER ELST A , Ma B, Scherpen FJ, de Jonge HJ, et al
    Repression of Vascular Endothelial Growth Factor Expression by the Runt-Related Transcription Factor 1 in Acute Myeloid Leukemia.
    Cancer Res. 2011.
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    February 2011
19. VAN LUIJN MM , van den Ancker W, Chamuleau ME, Zevenbergen A, et al
    Absence of class II-associated invariant chain peptide on leukemic blasts of patients promotes activation of autologous leukemia-reactive CD4+ T cells.
    Cancer Res. 2011.
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20. LILLY AJ , Khanim FL, Hayden RE, Luong QT, et al
    Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.
    Cancer Res. 2011;71:1177-86.
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21. SLUPIANEK A , Poplawski T, Jozwiakowski SK, Cramer K, et al
    BCR/ABL stimulates WRN to promote survival and genomic instability.
    Cancer Res. 2011;71:842-51.
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    January 2011
22. BUNACIU RP , Yen A
    Activation of the aryl hydrocarbon receptor AhR promotes retinoic acid-induced differentiation of myeloblastic leukemia cells by restricting expression of the stem cell transcription factor Oct4.
    Cancer Res. 2011.
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23. HU W , Ge X, You T, Xu T, et al
    Human CD59 inhibitor sensitizes rituximab-resistant lymphoma cells to complement-mediated cytolysis.
    Cancer Res. 2011.
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24. CHANG WH , Liu TC, Yang WK, Lee CC, et al
    Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib.
    Cancer Res. 2011;71:383-92.
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25. YUAN B , Zhang J, Wang H, Xiong L, et al
    6-Thioguanine Reactivates Epigenetically Silenced Genes in Acute Lymphoblastic Leukemia Cells by Facilitating Proteasome-mediated Degradation of DNMT1.
    Cancer Res. 2011.
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26. RUSHWORTH SA , Bowles KM, Macewan DJ
    High basal nuclear levels of Nrf2 in acute myeloid leukemia reduces sensitivity to proteasome inhibitors.
    Cancer Res. 2011.
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    December 2010
27. CHAO MP , Alizadeh AA, Tang C, Jan M, et al
    Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia.
    Cancer Res. 2010.
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28. CHANG MJ , Wu H, Achille NJ, Reisenauer MR, et al
    Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
    Cancer Res. 2010;70:10234-42.
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29. ZHANG X , Gu L, Li J, Shah N, et al
    Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells.
    Cancer Res. 2010;70:9895-904.
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    November 2010
30. FENOUILLE N , Puissant A, Dufies M, Robert G, et al
    Persistent Activation of the Fyn/ERK Kinase Signaling Axis Mediates Imatinib Resistance in Chronic Myelogenous Leukemia Cells through Upregulation of Intracellular SPARC.
    Cancer Res. 2010.
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31. VAN BERGEN CA , Rutten CE, Van Der Meijden ED, Van Luxemburg-Heijs SA, et al
    High-throughput characterization of 10 new minor histocompatibility antigens by whole genome association scanning.
    Cancer Res. 2010;70:9073-83.
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32. FANG C , Wang Y, Vu NT, Lin WY, et al
    Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples.
    Cancer Res. 2010;70:8299-308.
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    October 2010
33. DELLA PERUTA M , Martinelli G, Moratti E, Pintani D, et al
    Protein Tyrosine Phosphatase Receptor Type {gamma} Is a Functional Tumor Suppressor Gene Specifically Downregulated in Chronic Myeloid Leukemia.
    Cancer Res. 2010.
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34. CHEN Y , Deng J, Fujimoto J, Kadara H, et al
    Gprc5a Deletion Enhances the Transformed Phenotype in Normal and Malignant Lung Epithelial Cells by Eliciting Persistent Stat3 Signaling Induced by Autocrine Leukemia Inhibitory Factor.
    Cancer Res. 2010.
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35. GUO Y , Dolinko AV, Chinyengetere F, Stanton B, et al
    Blockade of the Ubiquitin Protease UBP43 Destabilizes the Transcription Factor PML/RAR{alpha} and Inhibits Growth of Acute Promyelocytic Leukemia.
    Cancer Res. 2010.
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    September 2010
36. GRUBER TA , Chang MS, Sposto R, Muschen M, et al
    Activation-Induced Cytidine Deaminase Accelerates Clonal Evolution in BCR-ABL1-Driven B-Cell Lineage Acute Lymphoblastic Leukemia.
    Cancer Res. 2010.
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37. CHIARINI F , Grimaldi C, Ricci F, Tazzari PL, et al
    Activity of the Novel Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 against T-Cell Acute Lymphoblastic Leukemia.
    Cancer Res. 2010.
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38. HUO H , Magro PG, Pietsch EC, Patel BB, et al
    Regulation of Multidrug Resistance 1 Transcription and Chemoresistance by the Mixed Lineage Leukemia 1 Protein.
    Cancer Res. 2010.
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39. SUBRAMANYAM D , Belair CD, Barry-Holson KQ, Lin H, et al
    PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia.
    Cancer Res. 2010.
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40. JIANG J , Cole D, Westwood N, Macpherson L, et al
    Crucial roles for protein kinase C isoforms in tumor-specific killing by apoptin.
    Cancer Res. 2010;70:7242-52.
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41. HOFBAUER SW , Pinon JD, Brachtl G, Haginger L, et al
    Modifying Akt Signaling in B-Cell Chronic Lymphocytic Leukemia Cells.
    Cancer Res. 2010.
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42. CHAPUIS N , Lacombe C, Tamburini J, Bouscary D, et al
    Insulin receptor A and IGF-1R in AML - Letter.
    Cancer Res. 2010;70:7010.
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43. RIMMELE P , Komatsu J, Hupe P, Roulin C, et al
    Spi-1/PU.1 oncogene accelerates DNA replication fork elongation and promotes genetic instability in the absence of DNA breakage.
    Cancer Res. 2010;70:6757-66.
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    August 2010
44. ROLL JD , Reuther GW
    CRLF2 and JAK2 in B-Progenitor Acute Lymphoblastic Leukemia: A Novel Association in Oncogenesis.
    Cancer Res. 2010.
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45. BUGGINS AG , Pepper C, Patten PE, Hewamana S, et al
    Interaction with vascular endothelium enhances survival in primary chronic lymphocytic leukemia cells via NF-{kappa}B activation and de novo gene transcription.
    Cancer Res. 2010.
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46. TANAKA Y , Nakasone H, Yamazaki R, Sato K, et al
    Single-Cell Analysis of T-Cell Receptor Repertoire of HTLV-1 Tax-Specific Cytotoxic T Cells in Allogeneic Transplant Recipients with Adult T-Cell Leukemia/Lymphoma.
    Cancer Res. 2010;70:6181-92.
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    July 2010
47. ROBERTS KG , Smith AM, McDougall F, Carpenter H, et al
    Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers.
    Cancer Res. 2010;70:5438-47.
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48. CREPIN R , Goenaga AL, Jullienne B, Bougherara H, et al
    Development of human single-chain antibodies to the transferrin receptor that effectively antagonize the growth of leukemias and lymphomas.
    Cancer Res. 2010;70:5497-506.
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49. DAVIS CC , Marti LC, Sempowski GD, Jeyaraj DA, et al
    Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: a critical step toward adoptive immunotherapy after cord blood transplantation.
    Cancer Res. 2010;70:5249-58.
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    June 2010
50. KALES SC , Ryan PE, Nau MM, Lipkowitz S, et al
    Cbl and human myeloid neoplasms: the Cbl oncogene comes of age.
    Cancer Res. 2010;70:4789-94.
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51. QUIROGA MP , Burger JA
    BCR-mediated decrease of CXCR4 and CD62L in CLL.
    Cancer Res. 2010;70:5194.
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