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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in Cancer

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    June 2008
  1. HUANG J , Li CY, Mesa RA, Wu W, et al
    Risk factors for leukemic transformation in patients with primary myelofibrosis.
    Cancer. 2008;112:2726-32.
    PubMed     Related articles    Abstract available


  2. KIM DH , Popradi G, Sriharsha L, Kamel-Reid S, et al
    No significance of derivative chromosome 9 deletion on the clearance kinetics of BCR/ABL fusion transcripts, cytogenetic or molecular response, loss of response, or treatment failure to imatinib mesylate therapy for chronic myeloid leukemia.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  3. ARICO M , Ziino O, Valsecchi MG, Cazzaniga G, et al
    Acute lymphoblastic leukemia and Down syndrome: presenting features and treatment outcome in the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP).
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


    May 2008
  4. INABA H , Fan Y, Pounds S, Geiger TL, et al
    Clinical and biologic features and treatment outcome of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  5. SAFDAR A , Rodriguez GH, Rueda AM, Wierda WG, et al
    Multiple-dose granulocyte-macrophage-colony-stimulating factor plus 23-valent polysaccharide pneumococcal vaccine in patients with chronic lymphocytic leukemia: a prospective, randomized trial of safety and immunogenicity.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  6. KURT B , Flynn P, Shenep JL, Pounds S, et al
    Prophylactic antibiotics reduce morbidity due to septicemia during intensive treatment for pediatric acute myeloid leukemia.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


    April 2008
  7. LIANG X , Graham DK
    Natural killer cell neoplasms.
    Cancer. 2008;112:1425-36.
    PubMed     Related articles    Abstract available


    March 2008
  8. THAKKAR SG , Fu AZ, Sweetenham JW, McIver ZA, et al
    Survival and predictors of outcome in patients with acute leukemia admitted to the intensive care unit.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  9. JABBOUR E , Cortes JE, Kantarjian HM
    Molecular monitoring in chronic myeloid leukemia: response to tyrosine kinase inhibitors and prognostic implications.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  10. MULROONEY DA , Dover DC, Li S, Yasui Y, et al
    Twenty years of follow-up among survivors of childhood and young adult acute myeloid leukemia: a report from the Childhood Cancer Survivor Study.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  11. HIJIYA N , Stewart CF, Zhou Y, Campana D, et al
    Phase II study of topotecan in combination with dexamethasone, asparaginase, and vincristine in pediatric patients with acute lymphoblastic leukemia in first relapse.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  12. ABDELHAMEED A , Pond GR, Mitsakakis N, Brandwein J, et al
    Outcome of patients who develop acute leukemia or myelodysplasia as a second malignancy after solid tumors treated surgically or with strategies that include chemotherapy and/or radiation.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  13. LEHMANN S , Ogawa S, Raynaud SD, Sanada M, et al
    Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


    January 2008
  14. MA W , Kantarjian H, O'Brien S, Jilani I, et al
    Enzymatic activity of circulating proteasomes correlates with clinical behavior in patients with chronic lymphocytic leukemia.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


  15. DE ANGULO G , Yuen C, Palla SL, Anderson PM, et al
    Absolute lymphocyte count is a novel prognostic indicator in ALL and AML: implications for risk stratification and future studies.
    Cancer. 2008;112:407-15.
    PubMed     Related articles    Abstract available


  16. HAINSWORTH JD , Vazquez ER, Spigel DR, Raefsky E, et al
    Combination therapy with fludarabine and rituximab followed by alemtuzumab in the first-line treatment of patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: a phase 2 trial of the Minnie Pearl Cancer Research Network.
    Cancer. 2008;.
    PubMed     Related articles    Abstract available


    December 2007
  17. PLESA C , Chelghoum Y, Plesa A, Elhamri M, et al
    Prognostic value of immunophenotyping in elderly patients with acute myeloid leukemia: a single-institution experience.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  18. KANTARJIAN H , O'Brien S, Shan J, Huang X, et al
    Cytogenetic and molecular responses and outcome in chronic myelogenous leukemia: need for new response definitions?
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  19. CREUTZIG U , Buchner T, Sauerland MC, Zimmermann M, et al
    Significance of age in acute myeloid leukemia patients younger than 30 years: a common analysis of the pediatric trials AML-BFM 93/98 and the adult trials AMLCG 92/99 and AMLSG HD93/98A.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    November 2007
  20. MIETTINEN M , Kraszewska E, Sobin LH, Lasota J, et al
    A nonrandom association between gastrointestinal stromal tumors and myeloid leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  21. KERN W , Haferlach C, Haferlach T, Schnittger S, et al
    Monitoring of minimal residual disease in acute myeloid leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  22. DEL POETA G , Del Principe MI, Buccisano F, Maurillo L, et al
    Consolidation and maintenance immunotherapy with rituximab improve clinical outcome in patients with B-cell chronic lymphocytic leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  23. JABBOUR E , Kantarjian H, Cortes J, Thomas D, et al
    PEG-IFN-alpha-2b therapy in BCR-ABL-negative myeloproliferative disorders: final result of a phase 2 study.
    Cancer. 2007;110:2012-8.
    PubMed     Related articles    Abstract available


    October 2007
  24. TAVERNIER E , Le QH, de Botton S, Dhedin N, et al
    Secondary or concomitant neoplasms among adults diagnosed with acute lymphoblastic leukemia and treated according to the LALA-87 and LALA-94 trials.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  25. YANADA M , Garcia-Manero G, Borthakur G, Ravandi F, et al
    Potential cure of acute myeloid leukemia : analysis of 1069 consecutive patients in first complete remission.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  26. HINDS PS , Hockenberry MJ, Gattuso JS, Kumar Srivastava D, et al
    Dexamethasone alters sleep and fatigue in pediatric patients with acute lymphoblastic leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    September 2007
  27. CHOW EJ , Pihoker C, Hunt K, Wilkinson K, et al
    Obesity and hypertension among children after treatment for acute lymphoblastic leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  28. ELSE M , Osuji N, Forconi F, Dearden C, et al
    The role of rituximab in combination with pentostatin or cladribine for the treatment of recurrent/refractory hairy cell leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  29. PUUMALA SE , Ross JA, Olshan AF, Robison LL, et al
    Reproductive history, infertility treatment, and the risk of acute leukemia in children with down syndrome: a Report From the Children's Oncology Group.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  30. CORTES J , Quintas-Cardama A, Garcia-Manero G, O'brien S, et al
    Phase 1 study of tipifarnib in combination with imatinib for patients with chronic myelogenous leukemia in chronic phase after imatinib failure.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  31. RIBEIRO KB , Lopes LF, de Camargo B
    Trends in childhood leukemia mortality in Brazil and correlation with social inequalities.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  32. RAVANDI F , Burnett AK, Agura ED, Kantarjian HM, et al
    Progress in the treatment of acute myeloid leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  33. KUENDGEN A , Gattermann N
    Valproic acid for the treatment of myeloid malignancies.
    Cancer. 2007;110:943-54.
    PubMed     Related articles    Abstract available


    August 2007
  34. BAZ R , Rodriguez C, Fu AZ, Jawde RA, et al
    Impact of remission induction chemotherapy on survival in older adults with acute myeloid leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  35. TRUONG TH , Beyene J, Hitzler J, Abla O, et al
    Features at presentation predict children with acute lymphoblastic leukemia at low risk for tumor lysis syndrome.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  36. DEININGER MW , Cortes J, Paquette R, Park B, et al
    The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in philadelphia chromosome-negative cells.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  37. PICCALUGA PP , Paolini S, Martinelli G
    Tyrosine kinase inhibitors for the treatment of Philadelphia chromosome-positive adult acute lymphoblastic leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  38. JACOBS SR , Small BJ, Booth-Jones M, Jacobsen PB, et al
    Changes in cognitive functioning in the year after hematopoietic stem cell transplantation.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    July 2007
  39. CORTES J , Jabbour E, Daley GQ, O'brien S, et al
    Phase 1 study of lonafarnib (SCH 66336) and imatinib mesylate in patients with chronic myeloid leukemia who have failed prior single-agent therapy with imatinib.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  40. BRANFORD S , Hughes T, Milner A, Koelmeyer R, et al
    Efficacy and safety of imatinib in patients with chronic myeloid leukemia and complete or near-complete cytogenetic response to interferon-alpha.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    June 2007
  41. ABRUZZESE E , Gozzetti A, Galimberti S, Trawinska MM, et al
    Characterization of Ph-negative abnormal clones emerging during imatinib therapy.
    Cancer. 2007;109:2466-72.
    PubMed     Related articles    Abstract available


  42. KNIPP S , Hildebrand B, Kundgen A, Giagounidis A, et al
    Intensive chemotherapy is not recommended for patients aged >60 years who have myelodysplastic syndromes or acute myeloid leukemia with high-risk karyotypes.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  43. JABBOUR E , Cortes J, Kantarjian H, Giralt S, et al
    Novel tyrosine kinase inhibitor therapy before allogeneic stem cell transplantation in patients with chronic myeloid leukemia: no evidence for increased transplant-related toxicity.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  44. SHANAFELT TD , Lin T, Geyer SM, Zent CS, et al
    Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia.
    Cancer. 2007;109:2291-8.
    PubMed     Related articles    Abstract available


    May 2007
  45. ALI NA , O'brien JM Jr, Blum W, Byrd JC, et al
    Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  46. ARMSTRONG JK , Hempel G, Koling S, Chan LS, et al
    Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  47. FERRER A , Salaverria I, Bosch F, Villamor N, et al
    Leukemic involvement is a common feature in mantle cell lymphoma.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    April 2007

  48. Erratum: Quintas-cardama A, Kantarjian H, Garcia-Manero G, et al. Phase I/II study of subcutaneous homoharringtonine in patients with chronic myeloid leukemia who have failed prior therapy. Cancer. 2007;109(2):248-55.
    Cancer. 2007;.
    PubMed     Related articles   


  49. MUSTO P , Rossini F, Gay F, Pitini V, et al
    Efficacy and safety of bortezomib in patients with plasma cell leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  50. JABBOUR E , Cortes JE, Giles FJ, O'brien S, et al
    Current and emerging treatment options in chronic myeloid leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  51. OTTMANN OG , Wassmann B, Pfeifer H, Giagounidis A, et al
    Imatinib compared with chemotherapy as front-line treatment of elderly patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL).
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  52. LE QH , Thomas X, Ecochard R, Iwaz J, et al
    Proportion of long-term event-free survivors and lifetime of adult patients not cured after a standard acute lymphoblastic leukemia therapeutic program: adult acute lymphoblastic leukemia-94 trial.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    March 2007
  53. KANTARJIAN HM , O'Brien S, Huang X, Garcia-Manero G, et al
    Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience.
    Cancer. 2007;109:1133-7.
    PubMed     Related articles    Abstract available


  54. MADDEN RM , Pui CH, Hughes WT, Flynn PM, et al
    Prophylaxis of Pneumocystis carinii pneumonia with atovaquone in children with leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  55. KANTARJIAN H , O'brien S, Talpaz M, Borthakur G, et al
    Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  56. FRUEHAUF S , Topaly J, Buss EC, Fischer T, et al
    Imatinib combined with mitoxantrone/etoposide and cytarabine is an effective induction therapy for patients with chronic myeloid leukemia in myeloid blast crisis.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    February 2007
  57. ETIENNE A , Esterni B, Charbonnier A, Mozziconacci MJ, et al
    Comorbidity is an independent predictor of complete remission in elderly patients receiving induction chemotherapy for acute myeloid leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  58. ARIBI A , Kantarjian HM, Estey EH, Koller CA, et al
    Combination therapy with arsenic trioxide, all-trans retinoic acid, and gemtuzumab ozogamicin in recurrent acute promyelocytic leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  59. KANTARJIAN HM , Cortes J, Guilhot F, Hochhaus A, et al
    Diagnosis and management of chronic myeloid leukemia: a survey of American and European practice patterns.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  60. KONOPLEV S , Rassidakis GZ, Estey E, Kantarjian H, et al
    Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  61. AZIZ Z , Iqbal J, Akram M, Saeed S, et al
    Treatment of chronic myeloid leukemia in the imatinib era: perspective from a developing country.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  62. BURNETT AK , Milligan D, Prentice AG, Goldstone AH, et al
    A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  63. HEIDEL F , Cortes J, Rucker FG, Aulitzky W, et al
    Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  64. KANTARJIAN HM
    Therapy for elderly patients with acute myeloid leukemia: a problem in search of solutions.
    Cancer. 2007;.
    PubMed     Related articles   


    January 2007
  65. OKI Y , Kantarjian HM, Gharibyan V, Jones D, et al
    Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


  66. ARIBI A , Borthakur G, Ravandi F, Shan J, et al
    Activity of decitabine, a hypomethylating agent, in chronic myelomonocytic leukemia.
    Cancer. 2007;.
    PubMed     Related articles    Abstract available


    December 2006
  67. BARTOLOZZI B , Bosi A, Orsi C
    Allogeneic hematopoietic stem cell transplantation as part of postremission therapy improves survival for adult patients with high-risk acute lymphoblastic leukemia: a meta-analysis.
    Cancer. 2006;.
    PubMed     Related articles   


  68. QUINTAS-CARDAMA A , Kantarjian H, Garcia-Manero G, O'brien S, et al
    Phase I/II study of subcutaneous homoharringtonine in patients with chronic myeloid leukemia who have failed prior therapy.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


    November 2006
  69. RUBNITZ JE , Razzouk BI, Lensing S, Pounds S, et al
    Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


  70. GALLAGHER G , Forrest DL
    Second solid cancers after allogeneic hematopoietic stem cell transplantation.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


  71. BLUM KA , Johnson JL, Niedzwiecki D, Piro LD, et al
    Prolonged follow-up after initial therapy with 2-chlorodeoxyadenosine in patients with indolent non-Hodgkin lymphoma: results of Cancer and Leukemia Group B Study 9153.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


  72. KERN W , Kohlmann A, Schoch C, Schnittger S, et al
    Comparison of mRNA abundance quantified by gene expression profiling and percentage of positive cells using immunophenotyping for diagnostic antigens in acute and chronic leukemias.
    Cancer. 2006;107:2401-7.
    PubMed     Related articles    Abstract available



  73. Erratum: Osuji N, Matutes E, Tjonnfjord G, et al. T-cell large granular lymphocyte leukemia: A report on the treatment of 29 patients and a review of the literature. Cancer. 2006;107(3):570-8.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


    October 2006
  74. KORNBLITH AB , Dowell JM, Herndon JE 2nd, Engelman BJ, et al
    Telephone monitoring of distress in patients aged 65 years or older with advanced stage cancer: a cancer and leukemia group B study.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


  75. SMOLEJ L , Benesova P
    Role of angiogenesis in chronic lymphocytic leukemia.
    Cancer. 2006;.
    PubMed     Related articles   


  76. FIEGL M , Falkner A, Hopfinger G, Brugger S, et al
    Routine clinical use of alemtuzumab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: a nation-wide retrospective study in Austria.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


  77. LEIBOVICI L , Paul M, Cullen M, Bucaneve G, et al
    Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
    Cancer. 2006;107:1743-51.
    PubMed     Related articles    Abstract available


  78. SCHULENBURG A , Ulrich-Pur H, Thurnher D, Erovic B, et al
    Neoplastic stem cells: A novel therapeutic target in clinical oncology.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


  79. DESCHLER B , Lubbert M
    Acute myeloid leukemia: Epidemiology and etiology.
    Cancer. 2006;.
    PubMed     Related articles    Abstract available


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