: The AMEDEO Literature Guide

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FPG #8: Alternative Treatments in Psychiatry
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Articles published in Blood
Retrieve available abstracts of 539 articles:
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January 2012

YOKOYAMA T , Toki T, Aoki Y, Kanezaki R, et al
Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia.
Blood. 2012.
PubMed Text format Related articles Abstract available

WALTER RB , Appelbaum FR, Estey EH, Bernstein ID, et al
Acute myeloid leukemia stem cells and CD33-targeted immunotherapy.
Blood. 2012.
PubMed Text format Related articles Abstract available

THOMSON KJ , Mackinnon S, Peggs KS
CMV-specific cellular therapy for acute myeloid leukemia?
Blood. 2012;119:1088-90.
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PIGAZZI M , Masetti R, Martinolli F, Manara E, et al
Presence of high-ERG expression is an independent unfavorable prognostic marker in MLL-rearranged childhood myeloid leukemia.
Blood. 2012;119:1086-7.
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ROOIJ MF , Kuil A, Geest CR, Eldering E, et al
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia.
Blood. 2012.
PubMed Text format Related articles Abstract available

ZHANG H , Li H, Xi HS, Li S, et al
HIF1alpha is required for survival maintenance of chronic myeloid leukemia stem cells.
Blood. 2012.
PubMed Text format Related articles Abstract available

GERBER JM , Smith BD, Ngwang B, Zhang H, et al
A clinically relevant population of leukemic CD34+CD38- cells in acute myeloid leukemia.
Blood. 2012.
PubMed Text format Related articles Abstract available

REDDICONTO G , Toto C, Palama I, De Leo S, et al
Targeting of GSK3beta promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors preserving normal stem cells.
Blood. 2012.
PubMed Text format Related articles Abstract available

RIGOLIN GM , Cibien F, Martinelli S, Formigaro L, et al
Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia with "normal" FISH: correlations with clinicobiological parameters.
Blood. 2012.
PubMed Text format Related articles Abstract available

CHEMALY RF , Hanmod SS, Rathod DB, Ghantoji SS, et al
The characteristics and outcomes of parainfluenza virus infections in 200 patients with leukemia or recipients of hematopoietic stem cell transplantation.
Blood. 2012.
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KUHN MW , Radtke I, Bullinger L, Goorha S, et al
High-resolution genomic profiling of adult and pediatric core-binding-factor acute myeloid leukemia reveals new recurrent genomic alterations.
Blood. 2012.
PubMed Text format Related articles Abstract available

GOODYEAR OC , Dennis M, Jilani NY, Loke J, et al
Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia.
Blood. 2012.
PubMed Text format Related articles Abstract available

MRAZ M , Dolezalova D, Plevova K, Stano Kozubik K, et al
MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia.
Blood. 2012.
PubMed Text format Related articles Abstract available

KANDA J , Hishizawa M, Utsunomiya A, Taniguchi S, et al
Impact of graft-versus-host disease on outcomes after allogeneic hematopoietic cell transplantation for adult T-cell leukemia: a retrospective cohort study.
Blood. 2012.
PubMed Text format Related articles Abstract available

KANTARJIAN H , O'Brien S, Jabbour E, Garcia-Manero G, et al
Improved survival in chronic myeloid leukemia since the introduction of imatinib therapy: a single-institution historical experience.
Blood. 2012.
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GERRIE AS , Zypchen LN, Connors JM
Fludarabine and rituximab for relapsed or refractory hairy cell leukemia.
Blood. 2012.
PubMed Text format Related articles Abstract available

MATSUURA S , Yan M, Lo MC, Ahn EY, et al
Negative effects of granulocyte-macrophage colony-stimulating factor signaling in a murine model of t(8;21)-induced leukemia.
Blood. 2012.
PubMed Text format Related articles Abstract available

December 2011

KANG H , Wilson CS, Harvey RC, Chen IM, et al
Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study.
Blood. 2011.
PubMed Text format Related articles Abstract available

XI L , Arons E, Navarro W, Calvo KR, et al
Both variant and IGHV4-34-expressing hairy cell leukemia lack the BRAF V600E mutation.
Blood. 2011.
PubMed Text format Related articles Abstract available

HAFERLACH C , Alpermann T, Schnittger S, Kern W, et al
Prognostic value of "monosomal karyotype" in comparison to "complex aberrant karyotype" in acute myeloid leukemia: study on 824 cases with aberrant karyotype.
Blood. 2011.
PubMed Text format Related articles Abstract available

RUCKER FG , Schlenk RF, Bullinger L, Kayser S, et al
TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome.
Blood. 2011.
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O'CALLAGHAN K , Lee L, Nguyen N, Hsieh MY, et al
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
Blood. 2011.
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HAMILTON A , Helgason GV, Schemionek M, Zhang B, et al
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival.
Blood. 2011.
PubMed Text format Related articles Abstract available

PONADER S , Chen SS, Buggy JJ, Balakrishnan K, et al
Bruton's tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo.
Blood. 2011.
PubMed Text format Related articles Abstract available

MILOJKOVIC D , Apperley JF, Gerrad G, Ibrahim AR, et al
Responses to second line tyrosine kinase inhibitors are durable: an intention to treat analysis in chronic myeloid leukemia patients.
Blood. 2011.
PubMed Text format Related articles Abstract available

HWANG KK , Chen X, Kozink DM, Gustilo M, et al
Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by co-culture with macrophage feeder cells.
Blood. 2011.
PubMed Text format Related articles Abstract available

KANTARJIAN HM , Shah NP, Cortes JE, Baccarani M, et al
Dasatinib or imatinib in newly diagnosed chronic phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION).
Blood. 2011.
PubMed Text format Related articles Abstract available

MCDERMOTT SP , Eppert K, Notta F, Isaac M, et al
A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside.
Blood. 2011.
PubMed Text format Related articles Abstract available

XIE R , Gao C, Li W, Zhu J, et al
Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells.
Blood. 2011.
PubMed Text format Related articles Abstract available

SHIBA N , Hasegawa D, Park MJ, Murata C, et al
CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia (FPD/AML).
Blood. 2011.
PubMed Text format Related articles Abstract available

BENDALL LJ
It's all in the timing.
Blood. 2011;118:5983-4.
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EHRHARDT H , Schrembs D, Moritz C, Wachter F, et al
Optimized anti-tumor effects of anthracyclines plus Vinca alkaloids using a novel, mechanism-based application schedule.
Blood. 2011;118:6123-31.
PubMed Text format Related articles Abstract available

November 2011

LU Y , Giver CR, Sharma A, Li JM, et al
Interferon-gamma and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity.
Blood. 2011.
PubMed Text format Related articles Abstract available

DEARDEN CE , Khot A, Else M, Hamblin M, et al
Alemtuzumab therapy in T-cell prolymphocytic leukemia: comparing efficacy in a series treated intravenously and a study piloting the subcutaneous route.
Blood. 2011;118:5799-802.
PubMed Text format Related articles Abstract available

WILLER A , Gerss J, Konig T, Franke D, et al
Anti-Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated E coli asparaginase: a retrospective analysis within the ALL-BFM trials.
Blood. 2011;118:5774-82.
PubMed Text format Related articles Abstract available

BAOU M , Norton JD, Murphy JJ
AU-rich RNA binding proteins in hematopoiesis and leukemogenesis.
Blood. 2011;118:5732-40.
PubMed Text format Related articles Abstract available

KAWEDIA JD , Liu C, Pei D, Cheng C, et al
Dexamethasone exposure and asparaginase antibodies affect relapse risk in acute lymphoblastic leukemia.
Blood. 2011.
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SENGUPTA A , Ficker A, Dunn S, Madhu M, et al
Bmi1 reprograms chronic myelogenous leukemia B-lymphoid progenitors to become B-ALL-initiating cells.
Blood. 2011.
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KUMARI A , Brendel C, Hochhaus A, Neubauer A, et al
Low BCR-ABL expression levels in hematopoietic precursor cells enable persistence of chronic myeloid leukemia under imatinib.
Blood. 2011.
PubMed Text format Related articles Abstract available

CAZZANIGA G , van Delft FW, Lo Nigro L, Ford AM, et al
Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia.
Blood. 2011;118:5559-64.
PubMed Text format Related articles Abstract available

CREUTZIG U , Zimmermann M, Bourquin JP, Dworzak MN, et al
Second induction with high-dose cytarabine and mitoxantrone: different impact on pediatric AML patients with t(8;21) and with inv(16).
Blood. 2011;118:5409-15.
PubMed Text format Related articles Abstract available

KAYSER S , Zucknick M, Dohner K, Krauter J, et al
Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome after different treatment strategies.
Blood. 2011.
PubMed Text format Related articles Abstract available

SAMPATH D , Liu C, Vasan K, Sulda M, et al
Histone deacetylases mediate the silencing of miR-15a, miR-16 and miR-29b in chronic lymphocytic leukemia.
Blood. 2011.
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DORES GM , Devesa SS, Curtis RE, Linet MS, et al
Acute leukemia incidence and patient survival among children and adults in the United States, 2001-2007.
Blood. 2011.
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KRYSOV S , Dias S, Paterson A, Mockridge CI, et al
Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells.
Blood. 2011.
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ROSSI D , Rasi S, Fabbri G, Spina V, et al
Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia.
Blood. 2011.
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HOU HA , Kuo YY, Liu CY, Chou WC, et al
DNMT3A mutations in acute myeloid leukemia-stability during disease evolution and the clinical implication.
Blood. 2011.
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SCHUH A
Anti-CD20: tales of identical twins?
Blood. 2011;118:5066-7.
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JAK M , van Bochove GG, Reits EA, Kallemeijn WW, et al
CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101.
Blood. 2011;118:5178-88.
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WIERDA WG , Padmanabhan S, Chan GW, Gupta IV, et al
Ofatumumab is active in patients with fludarabine-refractory CLL irrespective of prior rituximab: results from the phase 2 international study.
Blood. 2011;118:5126-9.
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BEN ABDELALI R , Asnafi V, Leguay T, Boissel N, et al
Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/FBXW7 mutations, but not of low ERG/BAALC expression: a GRAALL study.
Blood. 2011;118:5099-107.
PubMed Text format Related articles Abstract available

ARCAINI L , Zibellini S, Boveri E, Riboni R, et al
The BRAF V600E mutation in hairy cell leukemia and other mature B-cell neoplasms.
Blood. 2011.
PubMed Text format Related articles Abstract available

LU YF , Gavrilescu LC, Betancur M, Lazarides K, et al
Distinct graft-vs-leukemic stem cell effects of early or delayed donor leukocyte infusions in a mouse chronic myeloid leukemia model.
Blood. 2011.
PubMed Text format Related articles Abstract available

POLAK R , Buitenhuis M
The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

LEE Y , Chittezhath M, Andre V, Zhao H, et al
Protumoral role of monocytes in human B-cell precursor acute lymphoblastic leukemia: involvement of the chemokine CXCL10.
Blood. 2011.
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SALVESTRINI V , Zini R, Rossi L, Gulinelli S, et al
Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration and engraftment in immunodeficient mice.
Blood. 2011.
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JACOBSON CA , Ritz J
Time to put the CAR-T before the horse.
Blood. 2011;118:4761-2.
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LI L , Bailey E, Greenblatt S, Huso D, et al
Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice.
Blood. 2011;118:4935-45.
PubMed Text format Related articles Abstract available

YU Y , Wang D, Liu C, Kaosaard K, et al
Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORgammat in mice.
Blood. 2011;118:5011-20.
PubMed Text format Related articles Abstract available

BRENTJENS RJ , Riviere I, Park JH, Davila ML, et al
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias.
Blood. 2011;118:4817-28.
PubMed Text format Related articles Abstract available

BRECCIA M , Mazzarella L, Bagnardi V, Davide D, et al
Increased body mass index correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols.
Blood. 2011.
PubMed Text format Related articles Abstract available

CHEN J , Petrus M, Bamford R, Shih JH, et al
Increased serum soluble interleukin-15 receptor alpha (sIL-15Ralpha) levels in T-cell large granular lymphocyte leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

October 2011

ROSSI D , Bruscaggin A, Spina V, Rasi S, et al
Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness.
Blood. 2011.
PubMed Text format Related articles Abstract available

BUCCISANO F , Maurillo L, Del Principe MI, Del Poeta G, et al
Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia.
Blood. 2011.
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DOSE M , Gounari F
Sleeping beauty: does ETP-ALL awaken later?
Blood. 2011;118:4500-1.
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LARSON RA
CML: live long and prosper.
Blood. 2011;118:4499-500.
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BISAILLON R , Wilhelm BT, Krosl J, Sauvageau G, et al
C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein.
Blood. 2011;118:4682-9.
PubMed Text format Related articles Abstract available

HO PA , Kopecky KJ, Alonzo TA, Gerbing RB, et al
Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG.
Blood. 2011;118:4561-6.
PubMed Text format Related articles Abstract available

CORTES JE , Kantarjian HM, Brummendorf TH, Kim DW, et al
Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib.
Blood. 2011;118:4567-76.
PubMed Text format Related articles Abstract available

BERQUAM-VRIEZE KE , Nannapaneni K, Brett BT, Holmfeldt L, et al
Cell of origin strongly influences genetic selection in a mouse model of T-ALL.
Blood. 2011;118:4646-56.
PubMed Text format Related articles Abstract available

CHENG CK , Li L, Cheng SH, Ng K, et al
Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia.
Blood. 2011.
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TIACCI E , Schiavoni G, Forconi F, Santi A, et al
Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation.
Blood. 2011.
PubMed Text format Related articles Abstract available

NAGAI K , Ochi T, Fujiwara H, An J, et al
Aurora kinase A-specific T-cell receptor gene transfer redirects T lymphocytes to display effective anti-leukemia reactivity.
Blood. 2011.
PubMed Text format Related articles Abstract available

WLODARSKI MW , Motter J, Gorr TA, Olk-Batz C, et al
Abnormal promoter DNA methylation in juvenile myelomonocytic leukemia is not caused by mutation in DNMT3A.
Blood. 2011;118:4490-1.
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WAGNER JE , Blazar BR
Resurrecting the recalcitrant T-cell.
Blood. 2011;118:4302-3.
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KOJIMA K , McQueen T, Chen Y, Jacamo R, et al
p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1alpha-mediated down-regulation of CXCL12.
Blood. 2011;118:4431-9.
PubMed Text format Related articles Abstract available

CALPE E , Codony C, Baptista MJ, Abrisqueta P, et al
ZAP-70 enhances migration of malignant B lymphocytes toward CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation.
Blood. 2011;118:4401-10.
PubMed Text format Related articles Abstract available

MERINDOL N , Champagne MA, Duval M, Soudeyns H, et al
CD8(+) T-cell reconstitution in recipients of umbilical cord blood transplantation and characteristics associated with leukemic relapse.
Blood. 2011;118:4480-8.
PubMed Text format Related articles Abstract available

GROSSMANN V , Tiacci E, Holmes AB, Kohlmann A, et al
Whole-exome sequencing identifies mutations of BCOR in acute myeloid leukemia with normal karyotype.
Blood. 2011.
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DINI G , Zecca M, Balduzzi A, Messina C, et al
No difference in outcome between children and adolescents transplanted for acute lymphoblastic leukemia in second remission.
Blood. 2011.
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KUHNL A , Gokbuget N, Kaiser M, Schlee C, et al
Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

MOTIWALA T , Zanesi N, Datta J, Roy S, et al
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

KARP JE , Vener TI, Raponi M, Ritchie EK, et al
Multi-institutional Phase II clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia.
Blood. 2011.
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SERRA S , Horenstein AL, Vaisitti T, Brusa D, et al
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death.
Blood. 2011.
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MORABITO F , De Filippi R, Laurenti L, Zirlik K, et al
The cumulative amount of serum free light chain is a strong prognosticator in chronic lymphocytic leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

NAHAR R , Ramezani-Rad P, Mossner M, Duy C, et al
Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC.
Blood. 2011;118:4174-8.
PubMed Text format Related articles Abstract available

AU WY , Kumana CR, Lee HK, Lin SY, et al
Oral arsenic trioxide based maintenance regimens for first complete remission of acute promyelocytic leukemia: a ten-year follow-up study.
Blood. 2011.
PubMed Text format Related articles Abstract available

LI M , Collins R, Jiao Y, Ouillette P, et al
Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

NWABO KAMDJE AH , Krampera M
Notch signaling in acute lymphoblastic leukemia: any role for stromal microenvironment?
Blood. 2011.
PubMed Text format Related articles Abstract available

VAWDA A , Davis J, Vercauteren S
Leukemic transformation of anaplastic large-cell lymphoma.
Blood. 2011;118:3763.
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LOWENBERG B , Muus P, Ossenkoppele G, Rousselot P, et al
Phase I/II study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

ROUSSEAU J , Gagne V, Labuda M, Beaubois C, et al
ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

HEGDE S , Kaushal N, Ravindra KC, Chiaro C, et al
{Delta}12-prostaglandin J3, an omega-3 fatty acid-derived metabolite, selectively ablates leukemia stem cells in mice.
Blood. 2011.
PubMed Text format Related articles Abstract available

STAFFAS A , Kanduri M, Hovland R, Rosenquist R, et al
Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

HIJIYA N , Thomson B, Isakoff MS, Silverman LB, et al
Phase II trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory/relapsed acute lymphoblastic leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

September 2011

DENEBERG S , Guardiola P, Lennartsson A, Qu Y, et al
Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks.
Blood. 2011.
PubMed Text format Related articles Abstract available

SMITH MR , Neuberg D, Flinn IW, Grever MR, et al
Incidence of therapy-related myeloid neoplasia after initial therapy for chronic lymphocytic leukemia with fludarabine-cyclophosphamide versus fludarabine: long-term follow-up of US Intergroup Study E2997.
Blood. 2011;118:3525-7.
PubMed Text format Related articles Abstract available

FRISCH BJ , Ashton JM, Xing L, Becker MW, et al
Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

VELLENGA E , van Putten W, Ossenkoppele GJ, Verdonck LF, et al
Autologous peripheral blood stem cell transplantation for acute myeloid leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

RETTINGER E , Willasch AM, Kreyenberg H, Borkhardt A, et al
Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation.
Blood. 2011.
PubMed Text format Related articles Abstract available

BLAU O , Baldus CD, Hofmann WK, Thiel G, et al
Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts.
Blood. 2011.
PubMed Text format Related articles Abstract available

MIZUKAWA B , Wei J, Shrestha M, Wunderlich M, et al
Inhibition of Rac GTPase signaling and downstream pro-survival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

PIERI L , Spolverini A, Scappini B, Occhini U, et al
Concomitant occurrence of BCR-ABL and JAK2V617F mutation.
Blood. 2011;118:3445-6.
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ROBB RJ , Kreijveld E, Kuns RD, Wilson YA, et al
Type I-IFNs control GVHD and GVL responses after transplantation.
Blood. 2011;118:3399-409.
PubMed Text format Related articles Abstract available

KARUBE K , Nakagawa M, Tsuzuki S, Takeuchi I, et al
Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses.
Blood. 2011;118:3195-204.
PubMed Text format Related articles Abstract available

KUCHENBAUER F , Mah SM, Heuser M, McPherson A, et al
Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells.
Blood. 2011;118:3350-8.
PubMed Text format Related articles Abstract available

NICK HJ , Kim HG, Chang CW, Harris KW, et al
Distinct classes of c-Kit activating mutations differ in their ability to promote RUNX1-ETO-associated acute myeloid leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

NOORDERMEER SM , Sanders MA, Gilissen C, Tonnissen E, et al
High BRE expression predicts favorable outcome in adult acute myeloid leukemia, in particular among MLL-AF9 positive patients.
Blood. 2011.
PubMed Text format Related articles Abstract available

ETHIER MC , Blanco E, Lehrnbecher T, Sung L, et al
Lack of clarity in the definition of treatment-related mortality: pediatric acute leukemia and adult acute promyelocytic leukemia as examples.
Blood. 2011.
PubMed Text format Related articles Abstract available

CHU S , McDonald T, Lin A, Chakraborty S, et al
Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment.
Blood. 2011.
PubMed Text format Related articles Abstract available

FOA R , Vitale A, Vignetti M, Meloni G, et al
Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

WANG J , Han F, Wu J, Lee SW, et al
The role of Skp2 in hematopoietic stem cell quiescence, pool size and self-renewal.
Blood. 2011.
PubMed Text format Related articles Abstract available

NICOLINI FE , Basak GW, Soverini S, Martinelli G, et al
Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias.
Blood. 2011.
PubMed Text format Related articles Abstract available

HARRISON CJ
Key pathways as therapeutic targets.
Blood. 2011;118:2935-6.
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BALUSU R , Fiskus W, Rao R, Chong DG, et al
Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1.
Blood. 2011;118:3096-106.
PubMed Text format Related articles Abstract available

HOGAN LE , Meyer JA, Yang J, Wang J, et al
Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies.
Blood. 2011.
PubMed Text format Related articles Abstract available

KORNBLAU SM , Qiu YH, Zhang N, Singh N, et al
Abnormal expression of friend leukemia virus integration 1 protein is an adverse prognostic factor in acute myeloid leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

YAN XJ , Dozmorov I, Li W, Yancopoulos S, et al
Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

LI FJ , Kubagawa Y, McCollum MK, Wilson L, et al
Enhanced levels of both membrane-bound and soluble forms of IgM Fc receptor in patients with chronic lymphocytic leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

O'HARE T , Zabriskie MS, Eide CA, Agarwal A, et al
The BCR-ABL35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia.
Blood. 2011.
PubMed Text format Related articles Abstract available

DONATO NJ
Bcr-Abl adds another twist to cell fate.
Blood. 2011;118:2646-7.
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CHI AW , Chavez A, Xu L, Weber BN, et al
Identification of Flt3CD150 myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential.
Blood. 2011;118:2723-32.
PubMed Text format Related articles Abstract available

SHENG Z , Ma L, Sun JE, Zhu LJ, et al
BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription.
Blood. 2011;118:2840-8.
PubMed Text format Related articles Abstract available

BOND J , Adams S, Richards S, Vora A, et al
Polymorphism in the PAI-1 (SERPINE1) gene and the risk of osteonecrosis in children with acute lymphoblastic leukemia.
Blood. 2011;118:2632-3.
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LIM SH , Vaughan AT, Ashton-Key M, Williams EL, et al
Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy.
Blood. 2011;118:2530-40.
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August 2011

SHEN Y , Zhu YM, Fan X, Shi JY, et al
Gene mutation patterns and their prognostic impact in a cohort of 1,185 patients with acute myeloid leukemia.
Blood. 2011.
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USTUN C , Miller JS, Munn DH, Weisdorf DJ, et al
Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation?
Blood. 2011.
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GUTIERREZ A , Kentsis A, Sanda T, Holmfeldt L, et al
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.
Blood. 2011.
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AUE G , Du Y, Cleveland SM, Smith SB, et al
Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia.
Blood. 2011.
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JACOBSOHN DA , Arora M, Klein JP, Hassebroek A, et al
Risk factors associated with increased non-relapse mortality and with poor overall survival in children with chronic graft-versus-host disease.
Blood. 2011.
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ROY L , Tomowiak C, Guilhot F
Blood consult: high Sokal risk chronic myeloid leukemia and suboptimal response.
Blood. 2011.
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SOLITO S , Falisi E, Diaz-Montero CM, Doni A, et al
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.
Blood. 2011;118:2254-65.
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LACEY SF , La Rosa C, Kaltcheva T, Srivastava T, et al
Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice.
Blood. 2011;118:2159-69.
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SCHRAPPE M , Valsecchi MG, Bartram CR, Schrauder A, et al
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.
Blood. 2011;118:2077-84.
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FARREN TW , Giustiniani J, Liu FT, Tsitsikas DA, et al
Differential and tumor-specific expression of CD160 in B-cell malignancies.
Blood. 2011;118:2174-83.
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ALBERS C , Illert AL, Miething C, Leischner H, et al
An RNAi-based system for loss-of-function analysis identifies Raf1 as a crucial mediator of BCR-ABL-driven leukemogenesis.
Blood. 2011;118:2200-10.
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HELGASON GV , Karvela M, Holyoake TL
Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML.
Blood. 2011;118:2035-43.
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KOHRT HE , Muller AM, Baker J, Goldstein MJ, et al
Donor immunization with WT1 peptide augments anti-leukemic activity after MHC-matched bone marrow transplantation.
Blood. 2011.
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CLEMENTE MJ , Wlodarski MW, Makishima H, Viny AD, et al
Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia.
Blood. 2011.
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BARRETT DM , Seif AE, Carpenito C, Teachey DT, et al
Non-invasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for pre-clinical modeling.
Blood. 2011.
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ZHAO T , Satou Y, Sugata K, Miyazato P, et al
HTLV-1 bZIP factor enhances TGF-beta signaling through p300 coactivator.
Blood. 2011;118:1865-76.
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THOMAS X , Elhamri M, Raffoux E, Renneville A, et al
Comparison of high-dose cytarabine and timed-sequential chemotherapy as consolidation for younger adults with AML in first remission: the ALFA-9802 study.
Blood. 2011;118:1754-62.
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TEICHLER S , Illmer T, Roemhild J, Ovcharenko D, et al
MicroRNA29a regulates the expression of the nuclear oncogene Ski.
Blood. 2011;118:1899-902.
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ROSSI EA , Rossi DL, Cardillo TM, Stein R, et al
Preclinical studies on targeted delivery of multiple IFNalpha2b to HLA-DR in diverse hematologic cancers.
Blood. 2011;118:1877-84.
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CORM S , Roche L, Micol JB, Coiteux V, et al
Changes in the dynamics of the excess mortality rate in chronic phase-chronic myeloid leukemia over 1990-2007: a population study.
Blood. 2011.
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VERMA D , Kantarjian H, Strom SS, Rios MB, et al
Malignancies occurring during therapy with tyrosine kinase inhibitors (TKI) for chronic myeloid leukemia (CML) and other hematologic malignancies.
Blood. 2011.
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CHRISTENSEN DJ , Chen Y, Oddo J, Matta KM, et al
SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin's lymphoma: a predictor of aggressive disease and new treatment target.
Blood. 2011.
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NIELSEN SF , Bojesen SE, Birgens HS, Nordestgaard BG, et al
Risk of thyroid cancer, brain cancer, and non-Hodgkin's lymphoma following adult leukemia: a nationwide study.
Blood. 2011.
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MAGENAU J , Tobai H, Pawarode A, Braun T, et al
Clofarabine and busulfan conditioning facilitates engraftment and provides significant anti-tumor activity in non-remission hematologic malignancies.
Blood. 2011.
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YANG Y , Wang H, Yu H, Yeap BY, et al
IFN-{gamma} promotes graft-versus-leukemia effects without directly interacting with leukemia cells in mice after allogeneic hematopoietic cell transplantation.
Blood. 2011.
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CHANG ET , Canchola AJ, Cockburn M, Lu Y, et al
Adulthood residential ultraviolet radiation, sun sensitivity, dietary vitamin D, and risk of lymphoid malignancies in the California Teachers Study.
Blood. 2011;118:1591-9.
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SCANDURA JM , Roboz GJ, Moh M, Morawa E, et al
Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.
Blood. 2011;118:1472-80.
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GOTO E , Tomita A, Hayakawa F, Atsumi A, et al
Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatment.
Blood. 2011;118:1600-9.
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CHOU WC , Chou SC, Liu CY, Chen CY, et al
TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics.
Blood. 2011.
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JANKOWSKA AM , Makishima H, Tiu RV, Szpurka H, et al
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2 and DNMT3A.
Blood. 2011.
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BRAUN T , Itzykson R, Renneville A, de Renzis B, et al
Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase II trial.
Blood. 2011.
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LEE JH , Joo YD, Kim H, Bae SH, et al
A randomized trial comparing standard versus high-dose daunorubicin induction in patients with acute myeloid leukemia.
Blood. 2011.
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SCHWIND S , Marcucci G, Kohlschmidt J, Radmacher MD, et al
Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia.
Blood. 2011.
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RAVANDI F , O'Brien S, Jorgensen J, Pierce S, et al
Phase II study of cladribine followed by rituximab in patients with hairy cell leukemia.
Blood. 2011.
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ELLIOTT NE , Cleveland SM, Grann V, Janik J, et al
FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma.
Blood. 2011.
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BHATTACHARYA S , Zheng H, Tzimas C, Carroll M, et al
Bcr-abl signals to desensitize chronic myeloid leukemia cells to interferon alpha via accelerating the degradation of its receptor.
Blood. 2011.
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ESPOSITO N , Colavita I, Quintarelli C, Sica AR, et al
SHP1 expression accounts for resistance to imatinib treatment in Philadelphia chromosome-positive cells derived from patients with chronic myeloid leukemia.
Blood. 2011.
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FEUCHTINGER T
Susceptibility to childhood leukemia.
Blood. 2011;118:1189-90.
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STEVENSON FK , Krysov S, Davies AJ, Steele AJ, et al
B-cell receptor signaling in chronic lymphocytic leukemia.
Blood. 2011.
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HOLLINK IH , van den Heuvel-Eibrink MM, Arentsen-Peters ST, Pratcorona M, et al
NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern.
Blood. 2011.
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July 2011

HOELLENRIEGEL J , Meadows SA, Sivina M, Wierda WG, et al
The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia.
Blood. 2011.
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JABBOUR E , Kantarjian H, O'Brien S, Shan J, et al
The achievement of an early complete cytogenetic response is a major determinant for outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors.
Blood. 2011.
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MEENHUIS A , van Veelen PA, de Looper H, van Boxtel N, et al
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice.
Blood. 2011;118:916-25.
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OUILLETTE P , Collins R, Shakhan S, Li J, et al
Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia.
Blood. 2011.
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MAILANKODY S , Pfeiffer RM, Kristinsson SY, Korde N, et al
Risk of acute myeloid leukemia and myelodysplastic syndromes following multiple myeloma and its precursor disease (MGUS).
Blood. 2011.
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BAKST RL , Tallman MS, Douer D, Yahalom J, et al
How I treat extramedullary acute myeloid leukemia.
Blood. 2011.
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HAVELANGE V , Pekarsky Y, Nakamura T, Palamarchuk A, et al
IRF4 mutations in chronic lymphocytic leukemia.
Blood. 2011.
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CHOMEL JC , Bonnet ML, Sorel N, Bertrand A, et al
Leukemic stem cell persistency in chronic myeloid leukemia patients with sustained undetectable molecular residual disease.
Blood. 2011.
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CURTI A , Ruggeri L, D'Addio A, Bontadini A, et al
Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high-risk acute myeloid leukemia patients.
Blood. 2011.
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DEFAYS A , David A, de Gassart A, De Angelis Rigotti F, et al
BAD-LAMP is a novel biomarker of nonactivated human plasmacytoid dendritic cells.
Blood. 2011;118:609-17.
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HASFORD J , Baccarani M, Hoffmann V, Guilhot J, et al
Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score.
Blood. 2011;118:686-92.
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AL-HARBI S , Hill BT, Mazumder S, Singh K, et al
An anti-apoptotic Bcl-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737.
Blood. 2011.
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MONTILLO M , Tedeschi A, Petrizzi VB, Ricci F, et al
An open-label, pilot study of fludarabine, cyclophosphamide, and alemtuzumab (FCC) in relapsed/refractory patients with B-cell chronic lymphocytic leukemia.
Blood. 2011.
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SOKALSKI KM , Li SK, Welch I, Cadieux-Pitre HA, et al
Deletion of genes encoding PU.1 and Spi-B in B cells impairs differentiation and induces pre-B cell acute lymphoblastic leukemia.
Blood. 2011.
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LIAO A , Broeg K, Fox T, Tan SF, et al
Therapeutic efficacy of FTY720 in a rat model of natural killer cell leukemia.
Blood. 2011.
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MAURER MJ , Cerhan JR, Katzmann JA, Link BK, et al
Monoclonal and polyclonal serum free light chains and clinical outcome in chronic lymphocytic leukemia.
Blood. 2011.
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MALAVASI F , Deaglio S, Damle R, Cutrona G, et al
CD38 and chronic lymphocytic leukemia: a decade later.
Blood. 2011.
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LANE SW , Wang YJ, Lo Celso C, Ragu C, et al
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Blood. 2011.
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NISHIMOTO N , Arai S, Ichikawa M, Nakagawa M, et al
Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through downregulation of p19ARF.
Blood. 2011.
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NWABO KAMDJE AH , Mosna F, Bifari F, Lisi V, et al
Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.
Blood. 2011;118:380-9.
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GREEN CL , Evans CM, Zhao L, Hills RK, et al
The prognostic significance of IDH2 mutations in AML depends on the location of the mutation.
Blood. 2011;118:409-12.
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BYERS RJ , Currie T, Tholouli E, Rodig SJ, et al
MSI2 protein expression predicts unfavorable outcome in acute myeloid leukemia.
Blood. 2011.
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PARIKH SA , Keating MJ, O'Brien S, Wang X, et al
Frontline chemoimmunotherapy with fludarabine, cyclophosphamide, alemtuzumab, and rituximab (CFAR) for high-risk chronic lymphocytic leukemia.
Blood. 2011.
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EFFICACE F , Baccarani M, Breccia M, Alimena G, et al
Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population.
Blood. 2011.
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MARCU-MALINA V , Heijhuurs S, van Buuren M, Hartkamp L, et al
Redirecting alphabeta T cells against cancer cells by transfer of a broadly tumor-reactive gammadeltaT-cell receptor.
Blood. 2011;118:50-9.
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KLAMPFL T , Harutyunyan A, Berg T, Gisslinger B, et al
Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression.
Blood. 2011;118:167-76.
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ZHOU J , Bi C, Cheong LL, Mahara S, et al
The histone methyltransferase inhibitor DZNep upregulates TXNIP, increases ROS production, and targets leukemia cells in AML.
Blood. 2011.
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HILLS RK , Burnett AK
Applicability of a "pick a winner" trial design to acute myeloid leukemia.
Blood. 2011.
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VINCENT K , Roy DC, Perreault C
Next-generation leukemia immunotherapy.
Blood. 2011.
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GIOIA R , Leroy C, Drullion C, Lagarde V, et al
Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells.
Blood. 2011.
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HOMMINGA I , Zwaan CM, Manz CY, Parker C, et al
In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia.
Blood. 2011.
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BADOUX XC , Keating MJ, Wen S, Lee BN, et al
Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia.
Blood. 2011.
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BLUTEAU D , Gilles L, Hilpert M, Antony-Debre I, et al
Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia (FPD/AML).
Blood. 2011.
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June 2011

LEVIS M
FLT3/ITD AML and the law of unintended consequences.
Blood. 2011;117:6987-90.
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VOGLER M , Hamali HA, Sun XM, Bampton ET, et al
BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation.
Blood. 2011;117:7145-54.
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COENEN EA , Raimondi SC, Harbott J, Zimmermann M, et al
Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study.
Blood. 2011;117:7102-11.
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GHISI M , Corradin A, Basso K, Frasson C, et al
Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150.
Blood. 2011;117:7053-62.
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BISWAS K , Das R, Alter BP, Kuznetsov SG, et al
A comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assay.
Blood. 2011.
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ALFORD KA , Reinhardt K, Garnett C, Norton A, et al
Analysis of GATA1 mutations in Down syndrome transient myeloproliferative disorder and myeloid leukemia.
Blood. 2011.
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GOKBUGET N , Basara N, Baurmann H, Beck J, et al
High single drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation.
Blood. 2011.
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LEE KH , Lee JH, Lee JH, Kim DY, et al
Reduced-intensity conditioning therapy with busulfan, fludarabine, and anti-thymocyte globulin for HLA-haploidentical hematopoietic cell transplantation in acute leukemia and myelodysplastic syndrome.
Blood. 2011.
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PARK E , Gang EJ, Hsieh YT, Schaefer P, et al
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Blood. 2011.
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SHIDE K , Kameda T, Markovtsov V, Shimoda HK, et al
R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm.
Blood. 2011;117:6866-75.
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REN M , Cowell JK
Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.
Blood. 2011;117:6837-47.
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NGUYEN AT , Taranova O, He J, Zhang Y, et al
DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Blood. 2011;117:6912-22.
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WANG QF , Wu G, Mi S, He F, et al
MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome.
Blood. 2011;117:6895-905.
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MARZOCCHI G , Castagnetti F, Luatti S, Baldazzi C, et al
Variant Philadelphia translocations: molecular-cytogenetic characterization and prognostic influence on frontline imatinib therapy, a GIMEMA Working Party on CML analysis.
Blood. 2011;117:6793-800.
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SIMONSSON B , Gedde-Dahl T, Markevarn B, Remes K, et al
Combination of pegylated interferon-{alpha}2b with imatinib increases molecular response rates in patients with low or intermediate risk chronic myeloid leukemia.
Blood. 2011.
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FANG M , Storer B, Estey E, Othus M, et al
Outcome of acute myeloid leukemia patients with monosomal karyotype who undergo hematopoietic cell transplantation.
Blood. 2011.
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ZHANG J , Mullighan CG, Harvey RC, Wu G, et al
Key pathways are frequently mutated in high risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.
Blood. 2011.
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BONDANZA A , Hambach L, Aghai Z, Nijmeijer B, et al
IL-7 receptor expression identifies suicide gene-modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors.
Blood. 2011;117:6469-78.
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BAZARBACHI A , Suarez F, Fields P, Hermine O, et al
How I treat adult T-cell leukemia/lymphoma.
Blood. 2011.
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OCHI T , Fujiwara H, Okamoto S, An J, et al
Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked anti-leukemia reactivity and safety.
Blood. 2011.
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SCHMITZ M , Breithaupt P, Scheidegger N, Cario G, et al
Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.
Blood. 2011.
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BADOUX XC , Keating MJ, Wang X, O'Brien SM, et al
Cyclophosphamide, fludarabine, rituximab and alemtuzumab (CFAR) as salvage therapy for heavily pre-treated patients with chronic lymphocytic leukemia.
Blood. 2011.
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TATAREK J , Cullion K, Ashworth T, Gerstein R, et al
Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
Blood. 2011.
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ZHANG Y , Stehling-Sun S, Lezon-Geyda K, Juneja SC, et al
PR domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cells function.
Blood. 2011.
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MONTSERRAT E , Gribben JG
Autografting CLL: the game is over!
Blood. 2011;117:6057-8.
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PARK JH , Qiao B, Panageas KS, Schymura MJ, et al
Early death rate in acute promyelocytic leukemia remains high despite all-trans retinoic acid.
Blood. 2011.
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TANG M , Gonen M, Quintas-Cardama A, Cortes J, et al
Dynamics of chronic myeloid leukemia response to long-term targeted therapy reveal treatment effects on leukemic stem cells.
Blood. 2011.
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PAYNE EM , Bolli N, Rhodes J, Abdel-Wahab OI, et al
Ddx18 is essential for cell cycle progression in zebrafish hematopoietic cells and is mutated in human acute myeloid leukemia.
Blood. 2011.
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SLUPIANEK A , Dasgupta Y, Ren SY, Gurdek E, et al
Targeting RAD51 phosphotyrosine-315 to prevent unfaithful recombination repair in BCR-ABL1 leukemia.
Blood. 2011.
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BERTILACCIO MT , Simonetti G, Dagklis A, Rocchi M, et al
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.
Blood. 2011.
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VISONE R , Veronese A, Rassenti LZ, Balatti V, et al
MiR-181b is a biomarker of disease progression in chronic lymphocytic leukemia.
Blood. 2011.
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SALAS A , Ponnusamy S, Senkal CE, Meyers-Needham M, et al
Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A.
Blood. 2011;117:5941-52.
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HAEFLIGER S , Klebig C, Schaubitzer K, Schardt J, et al
Protein disulfide isomerase blocks CEBPA translation and is up-regulated during the unfolded protein response in AML.
Blood. 2011;117:5931-40.
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HOLE PS , Darley RL, Tonks A
Do reactive oxygen species play a role in myeloid leukemias?
Blood. 2011;117:5816-26.
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CORREIA DV , Fogli M, Hudspeth K, da Silva MG, et al
Differentiation of human peripheral blood V{delta}1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells.
Blood. 2011.
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May 2011

CHEN LS , Redkar S, Taverna P, Cortes JE, et al
Mechanisms of cytotoxicity to pim kinase inhibitor, SGI-1776, in acute myeloid leukemia.
Blood. 2011.
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VAN DER WEYDEN L , Giotopoulos G, Rust AG, Matheson LS, et al
Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice.
Blood. 2011.
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PERROT A , Luquet I, Pigneux A, Mugneret F, et al
Dismal prognostic value of monosomal karyotype in elderly patients with acute myeloid leukemia: a GOELAMS study of 186 patients with unfavorable cytogenetic abnormalities.
Blood. 2011.
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HAUER J , Mullighan C, Morillon E, Wang G, et al
Loss of p19Arf in a Rag1-/- B-cell precursor population initiates acute B-lymphoblastic leukemia.
Blood. 2011.
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HAUGG AM , Speel EJ, Pantulu ND, Pallasch C, et al
Fluorescence in situ hybridization confirms the presence of Merkel cell polyomavirus in chronic lymphocytic leukemia cells.
Blood. 2011;117:5776-7.
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PAGEL JM , Kenoyer AL, Back T, Hamlin DK, et al
Anti-CD45 pretargeted radioimmunotherapy using bismuth-213: high rates of complete remission and long-term survival in a mouse myeloid leukemia xenograft model.
Blood. 2011.
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LEUNG W , Campana D, Yang J, Pei D, et al
High success of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia.
Blood. 2011.
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ALMALTE Z , Samarani S, Iannello A, Debbeche O, et al
Novel association between activating killer-cell immunoglobulin-like receptor genes and childhood leukemia.
Blood. 2011.
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HOLLAND M , Castro FV, Alexander S, Smith D, et al
RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia.
Blood. 2011.
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PERROT A , Pionneau C, Nadaud S, Davi F, et al
A unique proteomic profile upon surface IgM ligation in unmutated chronic lymphocytic leukemia.
Blood. 2011.
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CHEN Y , Sullivan C, Peng C, Shan Y, et al
A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia.
Blood. 2011.
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LE MEIGNEN M , Auquier P, Barlogis V, Sirvent N, et al
Bone mineral density in adult-survivors of childhood acute leukemia: impact of hematopoietic stem cell transplantation and other treatment modalities.
Blood. 2011.
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ROCKOVA V , Abbas S, Wouters BJ, Erpelinck CA, et al
Risk-stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and expression markers.
Blood. 2011.
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BUDA-OKREGLAK EM , Cordaro DV
Simultaneous chronic myeloid leukemia and chronic lymphocytic leukemia.
Blood. 2011;117:5279.
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TREANOR LM , Volanakis EJ, Zhou S, Lu T, et al
Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.
Blood. 2011;117:5453-62.
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CAMPO E , Swerdlow SH, Harris NL, Pileri S, et al
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications.
Blood. 2011;117:5019-32.
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RISUENO RM , Campbell CJ, Dingwall S, Levadoux-Martin M, et al
Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease.
Blood. 2011.
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SOVERINI S , Hochhaus A, Nicolini FE, Gruber F, et al
Bcr-Abl kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inihibitors: recommendations from an expert panel on behalf of European LeukemiaNet.
Blood. 2011.
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MATLOUB Y , Bostrom BC, Hunger SP, Stork LC, et al
Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group.
Blood. 2011.
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KLEPPE M , Soulier J, Asnafi V, Mentens N, et al
PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.
Blood. 2011.
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SEKERES MA , Gundacker H, Lancet J, Advani A, et al
A phase 2 study of lenalidomide monotherapy in patients with deletion 5q acute myeloid leukemia: SWOG Study S0605.
Blood. 2011.
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JO SY , Granowicz EM, Maillard I, Thomas D, et al
Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Blood. 2011;117:4759-68.
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KILADJIAN JJ , Mesa RA, Hoffman R
The renaissance of interferon therapy for the treatment of myeloid malignancies.
Blood. 2011;117:4706-15.
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FOS J , Pabst T, Petkovic V, Ratschiller D, et al
Deficient CEBPA DNA binding function in normal karyotype AML patients is associated with favorable prognosis.
Blood. 2011;117:4881-4.
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ELMAAGACLI AH , Steckel NK, Koldehoff M, Hegerfeldt Y, et al
Early human cytomegalovirus replication after transplant is associated with a decreased relapse-risk: evidence for a putative virus-versus-leukemia effect AML patients.
Blood. 2011.
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KIM DH , Lee ST, Won HH, Kim S, et al
A genome-wide association study identifies novel loci associated with susceptibility to chronic myeloid leukemia.
Blood. 2011.
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BORNHAUSER M , Thiede C, Platzbecker U, Kiani A, et al
Prophylactic transfer of BCR-ABL-, PR1-, and WT1-reactive donor T cells after T-cell-depleted allogeneic hematopoietic cell transplantation in patients with chronic myeloid leukemia.
Blood. 2011.
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THOMS JA , Birger Y, Foster S, Knezevic K, et al
ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.
Blood. 2011.
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April 2011

RAND V , Parker H, Russell LJ, Schwab C, et al
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia.
Blood. 2011.
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BONNET M , Loosveld M, Montpellier B, Navarro JM, et al
Post-transcriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia.
Blood. 2011.
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ELF S , Blevins D, Jin L, Chung TW, et al
p90RSK2 is essential for FLT3-ITD-, but dispensable for BCR-ABL-induced myeloid leukemia.
Blood. 2011.
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SCHULZ AS , Glatting G, Hoenig M, Schuetz C, et al
Radioimmunotherapy-based conditioning for hematopoietic cell transplantation in children with malignant and nonmalignant diseases.
Blood. 2011;117:4642-50.
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TIU RV , Gondek LP, O'Keefe CL, Elson P, et al
Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies.
Blood. 2011;117:4552-60.
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BUYSE M , Squifflet P, Lange BJ, Alonzo TA, et al
Individual patient data meta-analysis of randomized trials evaluating interleukin-2 monotherapy as remission maintenance therapy in acute myeloid leukemia.
Blood. 2011.
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STEFFEN B , Knop M, Bergholz U, Vakhrusheva O, et al
AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein.
Blood. 2011;117:4328-37.
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NOTTAGE K , Lanctot J, Li Z, Neglia JP, et al
Long-term risk for subsequent leukemia after treatment for childhood cancer: a report from the Childhood Cancer Survivor Study.
Blood. 2011.
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WIERDA WG , Kipps TJ, Durig J, Griskevicius L, et al
Chemoimmunotherapy with ofatumumab, fludarabine, and cyclophosphamide (O-FC) in previously untreated patients with chronic lymphocytic leukemia.
Blood. 2011.
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PAZ-PRIEL I , Houng S, Dooher J, Friedman AD, et al
C/EBPalpha and C/EBPalpha oncoproteins regulate nfkb1 and displace histone deacetylases from NF-kappaB p50 homodimers to induce NF-kappaB target genes.
Blood. 2011;117:4085-94.
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O'CONNELL PA , Madureira PA, Berman JN, Liwski RS, et al
Regulation of S100A10 by the PML-RAR-alpha oncoprotein.
Blood. 2011;117:4095-105.
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MARVIN J , Swaminathan S, Kraker G, Chadburn A, et al
Normal bone marrow signal-transduction profiles: a requisite for enhanced detection of signaling dysregulations in AML.
Blood. 2011;117:e120-30.
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LUCAS CM , Harris RJ, Giannoudis A, Copland M, et al
Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression.
Blood. 2011.
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COUSTAN-SMITH E , Song G, Clark C, Key L, et al
New markers for minimal residual disease detection in acute lymphoblastic leukemia.
Blood. 2011.
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VAN DELFT FW , Horsley S, Colman S, Anderson K, et al
Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.
Blood. 2011.
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ASSELIN BL , Devidas M, Wang C, Pullen J, et al
Effectiveness of high dose methotrexate in T-cell lymphoblastic leukemia and advanced stage lymphoblastic lymphoma: a randomized study by the Children's Oncology Group (POG 9404).
Blood. 2011.
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QUELEN C , Lippert E, Struski S, Demur C, et al
Identification of a transforming MYB-GATA1 fusion gene in acute basophilic leukemia: a new entity in male infants.
Blood. 2011.
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IBRAHIM AR , Eliasson L, Apperley JF, Milojkovic D, et al
Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy.
Blood. 2011;117:3733-6.
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QUERE R , Karlsson G, Hertwig F, Rissler M, et al
SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
Blood. 2011.
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CORTES JE , Hochhaus A, le Coutre PD, Rosti G, et al
Minimal cross-intolerance with nilotinib in patients with chronic myeloid leukemia in chronic or accelerated phase who are intolerant to imatinib.
Blood. 2011.
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March 2011

NISHIWAKI S , Inamoto Y, Imamura M, Tsurumi H, et al
Reduced-intensity versus conventional myeloablative conditioning for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia in complete remission.
Blood. 2011;117:3698-9.
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BOISSEL N , Nibourel O, Renneville A, Huchette P, et al
Differential prognosis impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia.
Blood. 2011;117:3696-7.
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KRESS AK , Kalmer M, Rowan AG, Grassmann R, et al
The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF-kappaB signals.
Blood. 2011;117:3609-12.
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YOSHIMI A , Goyama S, Watanabe-Okochi N, Yoshiki Y, et al
Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins.
Blood. 2011;117:3617-28.
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VAIDYA R , Caramazza D, Begna KH, Gangat N, et al
Monosomal karyotype in primary myelofibrosis is detrimental to both overall and leukemia-free survival.
Blood. 2011.
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GUGLIOTTA G , Castagnetti F, Palandri F, Breccia M, et al
Frontline imatinib treatment of chronic myeloid leukemia: no impact of age on outcome, a survey by the GIMEMA CML WP.
Blood. 2011.
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REDELL MS , Ruiz MJ, Alonzo TA, Gerbing RB, et al
Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and apoptosis induction by a novel small molecule Stat3 inhibitor.
Blood. 2011.
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UMINO A , Nakagawa M, Utsunomiya A, Tsukasaki K, et al
Clonal evolution of adult T-cell leukemia/lymphoma takes place in lymph node.
Blood. 2011.
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ABLAIN J , de The H
Revisiting the differentiation paradigm in acute promyelocytic leukemia.
Blood. 2011.
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CHEN W , O'Sullivan MG, Hudson W, Kersey J, et al
Modeling human infant MLL leukemia in mice: leukemia from fetal liver differs from that originating in postnatal marrow.
Blood. 2011;117:3474-5.
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JULIUSSON G
Most 70- to 79-year-old patients with acute myeloid leukemia do benefit from intensive treatment.
Blood. 2011;117:3473-3474.
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QUINTARELLI C , Dotti G, Hasan ST, De Angelis B, et al
High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells.
Blood. 2011;117:3353-62.
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LEVIS M , Ravandi F, Wang ES, Baer MR, et al
Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse.
Blood. 2011;117:3294-301.
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SATO T , Yang X, Knapper S, White P, et al
FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo.
Blood. 2011;117:3286-93.
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KARP JE , Smith BD, Resar LS, Greer JM, et al
Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias.
Blood. 2011;117:3302-10.
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H BAYDOUN H , Pancewicz J, Nicot C
Human T-cell leukemia virus p30 inhibits homologous recombination and favors unfaithful DNA repair.
Blood. 2011.
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HERMAN SE , Gordon AL, Hertlein E, Ramanunni A, et al
Bruton's tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.
Blood. 2011.
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CHEN SJ , Zhou GB, Zhang XW, Mao JH, et al
From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia.
Blood. 2011.
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YIN L , Wu Z, Avigan D, Rosenblatt J, et al
MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells.
Blood. 2011.
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FERNANDEZ HF , Sun Z, Litzow MR, Luger SM, et al
Autologous transplantation gives encouraging results for young adults with favorable-risk acute myeloid leukemia but is not improved with gemtuzumab ozogamicin.
Blood. 2011.
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TERIAKY A , Hsia CC
Plasma cell leukemia mimicking chronic lymphocytic leukemia.
Blood. 2011;117:2991.
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SUN H , Kapuria V, Peterson LF, Fang D, et al
Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.
Blood. 2011;117:3151-62.
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BADOUX XC , Keating MJ, Wang X, O'Brien SM, et al
Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL.
Blood. 2011;117:3016-24.
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OLK-BATZ C , Poetsch AR, Nollke P, Claus R, et al
Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia (JMML) with poor outcome.
Blood. 2011.
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GIORDANO ATTIANESE GM , Marin V, Hoyos V, Savoldo B, et al
In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor.
Blood. 2011.
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SUTTON L , Chevret S, Tournilhac O, Divine M, et al
Autologous stem cell transplantation as a first-line treatment strategy for chronic lymphocytic leukemia: a multicenter randomized controlled trial.
Blood. 2011.
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XIAO H , Shi J, Luo Y, Tan Y, et al
First report of multiple CEBPA mutations contributing to donor origin of leukemia relapse after allogeneic hematopoietic stem cell transplantation.
Blood. 2011.
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BACHANOVA V , Sandhu K, Yohe S, Cao Q, et al
Allogeneic hematopoietic stem cell transplantation overcomes the adverse prognostic impact of CD20 expression in acute lymphoblastic leukemia.
Blood. 2011.
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KANNAN S , Fang W, Song G, Mullighan CG, et al
Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression.
Blood. 2011;117:2891-900.
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MONTES R , Ayllon V, Gutierrez-Aranda I, Prat I, et al
Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia.
Blood. 2011.
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AVVISATI G , Lo-Coco F, Paoloni FP, Petti MC, et al
AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance.
Blood. 2011.
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ZHOU Q , Munger ME, Veenstra RG, Weigel BJ, et al
Co-expression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.
Blood. 2011.
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BAGNARA D , Kaufman MS, Calissano C, Marsilio S, et al
A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease.
Blood. 2011.
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HERMAN SE , Lapalombella R, Gordon AL, Ramanunni A, et al
The role of phosphatidylinositol 3-kinase-{delta} in the immunomodulatory effects of lenalidomide in chronic lymphocytic leukemia.
Blood. 2011.
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DAMM F , Heuser M, Morgan M, Wagner K, et al
Integrative prognostic risk score in acute myeloid leukemia with normal karyotype.
Blood. 2011.
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KUSTER L , Grausenburger R, Fuka G, Kaindl U, et al
ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.
Blood. 2011;117:2658-67.
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RAMIREZ-HERRICK AM , Mullican SE, Sheehan AM, Conneely OM, et al
Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice.
Blood. 2011;117:2681-90.
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ARONS E , Roth L, Sapolsky J, Suntum T, et al
Evidence of canonical somatic hypermutation in hairy cell leukemia.
Blood. 2011.
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February 2011

AUGEREAU A , T'kint de Roodenbeke C, Simonet T, Bauwens S, et al
Telomeric damage in early stage of chronic lymphocytic leukemia correlates with shelterin dysregulation.
Blood. 2011.
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TASKESEN E , Bullinger L, Corbacioglu A, Sanders MA, et al
Prognostic impact, concurrent genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further evidence for CEBPA double mutant AML as a distinctive disease entity.
Blood. 2011;117:2469-75.
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SCHNITTGER S , Dicker F, Kern W, Wendland N, et al
RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis.
Blood. 2011;117:2348-57.
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MAKISHIMA H , Jankowska AM, McDevitt MA, O'Keefe C, et al
CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia.
Blood. 2011.
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DU W , Li X, Sipple J, Pang Q, et al
Overexpression of IL-3Rα on CD34+CD38- stem cells defines leukemia-initiating cells in FA AML.
Blood. 2011.
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CHOU FS , Wunderlich M, Griesinger A, Mulloy JC, et al
N-Ras(G12D) induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene.
Blood. 2011;117:2237-40.
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SAWADA Y , Hino R, Hama K, Ohmori S, et al
The type of skin eruptions is an independent prognostic indicator for adult T-cell leukemia/lymphoma.
Blood. 2011.
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QUENTIN S , Cuccuini W, Ceccaldi R, Nibourel O, et al
Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions.
Blood. 2011.
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VAN ROOSBROECK K , Cox L, Tousseyn T, Lahortiga I, et al
JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma.
Blood. 2011.
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TSUZUKI S , Taguchi O, Seto M
Promotion and maintenance of leukemia by ERG.
Blood. 2011.
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HE J , Nguyen AT, Zhang Y
KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia.
Blood. 2011.
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DUZKALE H , Schweighofer CD, Coombes KR, Barron LL, et al
LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts over-all survival in untreated patients.
Blood. 2011.
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LI Q , Haigis KM, McDaniel A, Harding-Theobald E, et al
Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.
Blood. 2011;117:2022-32.
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GERBAULET A , Wickenhauser C, Scholten J, Peschke K, et al
Mast cell hyperplasia, B-cell malignancy, and intestinal inflammation in mice with conditional expression of a constitutively active kit.
Blood. 2011;117:2012-21.
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SLAGER SL , Rabe KG, Achenbach SJ, Vachon CM, et al
Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.
Blood. 2011;117:1911-6.
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JU W , Zhang M, Jiang JK, Thomas CJ, et al
CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP.
Blood. 2011;117:1938-46.
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SATO N , Sabzevari H, Fu S, Ju W, et al
Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15 transgenic mice requires the cis-expression of IL-15R{alpha}
Blood. 2011.
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KOLLMANN K , Heller G, Ott RG, Scheicher R, et al
C-JUN promotes BCR-ABL induced lymphoid leukemia by inhibiting methylation of the 5' region of Cdk6.
Blood. 2011.
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SERGEEVA A , Alatrash G, He H, Ruisaard K, et al
An anti-PR1/HLA-A2 T cell receptor-like antibody mediates complement dependent cytotoxicity against acute myeloid leukemia progenitor cells.
Blood. 2011.
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VARGOVA K , Curik N, Burda P, Basova P, et al
MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia.
Blood. 2011.
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MOHR J , Helfrich H, Fuge M, Eldering E, et al
DNA damage-induced transcriptional program in CLL: biological and diagnostic implications for functional p53 testing.
Blood. 2011;117:1622-32.
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OFFMAN MN , Krol M, Patel N, Krishnan S, et al
Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity.
Blood. 2011;117:1614-21.
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HOSKING FJ , Leslie S, Dilthey A, Moutsianas L, et al
MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia.
Blood. 2011;117:1633-40.
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PARK J , Hedvat CV, Tallman MS
Blood consult: acute myeloid leukemia and the t(8;21)(q22;22).
Blood. 2011.
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January 2011

OUDIN C , Simeoni MC, Sirvent N, Contet A, et al
Prevalence and risk factors of the metabolic syndrome in adult survivors of childhood leukemia.
Blood. 2011.
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CHRISTOPOULOS P , Pfeifer D, Bartholome K, Follo M, et al
Definition and characterization of the systemic T-cell dysregulation in untreated indolent B-cell lymphoma and very early CLL.
Blood. 2011.
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BOULOS N , Mulder HL, Calabrese CR, Morrison JB, et al
Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemia.
Blood. 2011.
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JIANG Q , Xu LP, Liu DH, Liu KY, et al
Imatinib mesylate versus allogeneic hematopoietic stem cell transplantation for patients with chronic myelogenous leukemia in accelerated phase.
Blood. 2011.
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CHEN SS , Claus R, Lucas DM, Yu L, et al
Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL.
Blood. 2011;117:862-71.
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CARTER BZ , Qiu YH, Zhang N, Coombes KR, et al
Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML.
Blood. 2011;117:780-7.
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BRUNSTEIN CG , Miller JS, Cao Q, McKenna DH, et al
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics.
Blood. 2011;117:1061-70.
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MAETZIG T , Brugman MH, Bartels S, Heinz N, et al
Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells.
Blood. 2011.
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HISATOMI T , Sueoka-Aragane N, Sato A, Tomimasu R, et al
NK314 potentiates anti-tumor activity with adult T-cell leukemia-lymphoma cellsby inhibition of dual targets on topoisomerase II{alpha} and DNA-dependent protein kinase.
Blood. 2011.
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NELSON EA , Walker SR, Weisberg E, Bar-Natan M, et al
The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors.
Blood. 2011.
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LANNUTTI BJ , Meadows SA, Herman SE, Kashishian A, et al
CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability.
Blood. 2011;117:591-4.
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MATUTES E , Pickl WF, Van't Veer M, Morilla R, et al
Mixed phenotype acute leukemia (MPAL): clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification.
Blood. 2011.
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ELLING C , Erben P, Walz C, Frickenhaus M, et al
Novel imatinib-sensitive PDGFRA activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease.
Blood. 2011.
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WARSCH W , Kollmann K, Eckelhart E, Fajmann S, et al
High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia.
Blood. 2011.
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ALLEN JC , Talab F, Zuzel M, Lin K, et al
c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells.
Blood. 2011.
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DEMAREST RM , Dahmane N, Capobianco AJ
Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia.
Blood. 2011.
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ZUNA J , Madzo J, Krejci O, Zemanova Z, et al
ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia.
Blood. 2011;117:368-9.
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ASTWOOD E , Vora A
Erythroblastic islands.
Blood. 2011;117:10.
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GREAVES M , Colman SM, Kearney L, Ford AM, et al
Fusion genes in cord blood.
Blood. 2011;117:369-70.
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TADOKORO S , Nakazawa T, Kamae T, Kiyomizu K, et al
A potential role for alpha-actinin in inside-out alphaIIbbeta3 signaling.
Blood. 2011;117:250-8.
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MAJHAIL NS , Brazauskas R, Rizzo JD, Sobecks RM, et al
Secondary solid cancers after allogeneic hematopoietic cell transplantation using busulfan-cyclophosphamide conditioning.
Blood. 2011;117:316-22.
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KATO N , Kitaura J, Doki N, Komeno Y, et al
Two types of C/EBPalpha mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models.
Blood. 2011;117:221-33.
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LAUSTEN-THOMSEN U , Madsen HO, Vestergaard TR, Hjalgrim H, et al
Prevalence of t(12;21)[ETV6-RUNX1]-positive cells in healthy neonates.
Blood. 2011;117:186-9.
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TOMIC J , Lichty B, Spaner DE
Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia.
Blood. 2011.
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December 2010

FREYER DR , Devidas M, La M, Carroll WL, et al
Post-relapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group.
Blood. 2010.
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ZHONG F , Harr MW, Bultynck G, Monaco G, et al
Induction of Ca2+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction.
Blood. 2010.
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MIYAWAKI S , Ohtake S, Fujisawa S, Kiyoi H, et al
A randomized comparison of four courses of standard-dose multiagent chemotherapy versus three courses of high-dose cytarabine alone in post-remission therapy for acute myeloid leukemia in adults: the JALSG AML201 study.
Blood. 2010.
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DANESE MD , Griffiths RI, Gleeson M, Satram-Hoang S, et al
An observational study of outcomes after initial infused therapy in Medicare patients diagnosed with chronic lymphocytic leukemia.
Blood. 2010.
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WELCH JS , Klco JM, Varghese N, Nagarajan R, et al
Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.
Blood. 2010.
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LAMY T , Loughran TP Jr
How we treat LGL leukemia.
Blood. 2010.
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ARAI S , Yoshimi A, Shimabe M, Ichikawa M, et al
Evi-1 is a transcriptional target of MLL oncoproteins in hematopoietic stem cells.
Blood. 2010.
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DIAZ-BEYA M , Rozman M, Pratcorona M, Torrebadell M, et al
The prognostic value of multilineage dysplasia in de novo acute myeloid leukemia patients with intermediate-risk cytogenetics is dependent on NPM1 mutational status.
Blood. 2010;116:6147-8.
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DEENIK W , van der Holt B, Janssen JJ, Chu IW, et al
Polymorphisms in the multidrug resistance gene MDR1 (ABCB1) predict for molecular resistance in patients with newly diagnosed chronic myeloid leukemia receiving high-dose imatinib.
Blood. 2010;116:6144-5.
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HASSANE DC , Sen S, Minhajuddin M, Rossi RM, et al
Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.
Blood. 2010;116:5983-90.
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DAGHISTANI M , Marin D, Khorashad JS, Wang L, et al
EVI-1 oncogene expression predicts survival in chronic-phase CML patients resistant to imatinib treated with second-generation tyrosine kinase inhibitors.
Blood. 2010;116:6014-7.
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NIJMEIJER BA , van Schie ML, Halkes CJ, Griffioen M, et al
A mechanistic rationale for combining alemtuzumab and rituximab in the treatment of ALL.
Blood. 2010;116:5930-40.
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PULIKKAN JA , Peramangalam PS, Dengler V, Ho PA, et al
C/EBPalpha regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations.
Blood. 2010;116:5638-49.
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ASHWORTH TD , Pear WS, Chiang MY, Blacklow SC, et al
Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.
Blood. 2010;116:5455-64.
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JEANNET R , Mastio J, Macias-Garcia A, Oravecz A, et al
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
Blood. 2010;116:5443-54.
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SCHNITTGER S , Haferlach C, Ulke M, Alpermann T, et al
IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status.
Blood. 2010;116:5486-96.
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JABBOUR E , Cortes J, Santos FP, Jones D, et al
Results of allogeneic hematopoietic stem cell transplantation for chronic myelogenous leukemia patients who failed tyrosine kinase inhibitors after developing BCR-ABL1 kinase domain mutations.
Blood. 2010.
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KAWEDIA JD , Kaste SC, Pei D, Panetta JC, et al
Pharmacokinetic, pharmacodynamic and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia.
Blood. 2010.
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CHIORAZZI N , Ferrarini M
Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.
Blood. 2010.
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MEI HE , Frolich D, Giesecke C, Loddenkemper C, et al
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
Blood. 2010;116:5181-90.
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MANDAWAT A , Fiskus W, Buckley KM, Robbins K, et al
Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists.
Blood. 2010;116:5306-15.
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FAN J , Li L, Small D, Rassool F, et al
Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy.
Blood. 2010;116:5298-305.
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GU ZM , Wu YL, Zhou MY, Liu CX, et al
Pharicin B stabilizes retinoic acid receptor-alpha and presents synergistic differentiation induction with ATRA in myeloid leukemic cells.
Blood. 2010;116:5289-97.
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KINDLER T , Lipka DB, Fischer T
FLT3 as a therapeutic target in AML: still challenging after all these years.
Blood. 2010;116:5089-102.
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MONTESINOS P , Rayon C, Vellenga E, Brunet S, et al
Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens.
Blood. 2010.
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CHEVILLARD G , Paquet M, Blank V
Nfe2l3 (Nrf3) deficiency predisposes mice to T-cell lymphoblastic lymphoma.
Blood. 2010.
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ALLERS K , Hutter G, Hofmann J, Loddenkemper C, et al
Evidence for the cure of HIV infection by CCR5{Delta}32/{Delta}32 stem cell transplantation.
Blood. 2010.
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BILLOT K , Soeur J, Chereau F, Arrouss I, et al
Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated to epigenetic modifications.
Blood. 2010.
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EICHHORST BF , Fischer K, Fink AM, Elter T, et al
Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis.
Blood. 2010.
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CHARFI C , Voisin V, Levros LC Jr, Edouard E, et al
Gene profiling of Graffi murine leukemia virus induced lymphoid leukemias: identification of leukemia markers and Fmn2 as a potential oncogene.
Blood. 2010.
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MAO X , Cao B, Wood TE, Hurren R, et al
A small molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway.
Blood. 2010.
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GHOSH AK , Secreto C, Boysen J, Sassoon T, et al
A novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of non-receptor kinases: implications for therapy.
Blood. 2010.
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KULOZIK AE
Taking childhood leukemia personally.
Blood. 2010;116:4737-8.
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KAYSER S , Dohner K, Krauter J, Kohne CH, et al
The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2,853 adult patients with newly diagnosed AML.
Blood. 2010.
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EHLERT K , Groll AH
Myelosarcoma in Fanconi anemia.
Blood. 2010;116:4744.
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FLANDRIN-GRESTA P , Callanan M, Nadal N, Jaubert J, et al
Transmission of leukemic donor cells by allogeneic stem cell transplantation in a context of familial CLL: should we screen donors for MBL?
Blood. 2010;116:5077-8.
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AL-KALI A , Verstovsek S, Kantarjian H, Luthra R, et al
Competing cell clones in myeloproliferative neoplasm.
Blood. 2010;116:5074-5.
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DIAKOS C , Zhong S, Xiao Y, Zhou M, et al
TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a.
Blood. 2010;116:4885-93.
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SULJAGIC M , Longo PG, Bennardo S, Perlas E, et al
The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Emu- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling.
Blood. 2010;116:4894-905.
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JANIKASHVILI N , Lacasse CJ, Larmonier C, Trad M, et al
Allogeneic effector/memory Th-1 cells impair FoxP3+ regulatory T lymphocytes and synergize with chaperone-rich cell lysate vaccine to treat leukemia.
Blood. 2010.
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COSSET E , Hamdan G, Jeanpierre S, Voeltzel T, et al
Deregulation of TWIST-1 in the CD34+ compartment represents a novel prognostic factor in chronic myeloid leukemia (CML).
Blood. 2010.
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November 2010

ZHAO F , Zhang Y, Wang H, Jin M, et al
Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease.
Blood. 2010.
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SIVINA M , Hartmann E, Kipps TJ, Rassenti L, et al
CCL3 (MIP-1{alpha}) plasma levels and the risk for disease progression in chronic lymphocytic leukemia (CLL).
Blood. 2010.
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WESTON VJ , Oldreive CE, Skowronska A, Oscier DG, et al
The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.
Blood. 2010;116:4578-87.
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WHITE HE , Matejtschuk P, Rigsby P, Gabert J, et al
Establishment of the first World Health Organization International Genetic Reference Panel for quantitation of BCR-ABL mRNA.
Blood. 2010;116:e111-7.
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HUDECEK M , Schmitt TM, Baskar S, Lupo-Stanghellini MT, et al
The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor.
Blood. 2010;116:4532-41.
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SINENKO SA , Hung T, Moroz T, Tran QM, et al
Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model.
Blood. 2010;116:4612-20.
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BRUNSTEIN CG , Gutman JA, Weisdorf DJ, Woolfrey AE, et al
Allogeneic hematopoietic cell transplantation for hematologic malignancy: relative risks and benefits of double umbilical cord blood.
Blood. 2010;116:4693-9.
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BANSAL H , Bansal S, Rao M, Foley KP, et al
Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias.
Blood. 2010;116:4591-9.
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KUROSAWA S , Yamaguchi T, Miyawaki S, Uchida N, et al
A Markov decision analysis of allogeneic hematopoietic cell transplantation versus chemotherapy in patients with acute myeloid leukemia in first remission.
Blood. 2010.
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MICHALLET M , Dreger P, Sutton L, Brand R, et al
Autologous hematopoietic stem cell transplantation in chronic lymphocytic leukemia: results of European intergroup randomized trial comparing autografting versus observation.
Blood. 2010.
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ENSOR HM , Schwab C, Russell LJ, Richards SM, et al
Demographic, clinical and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial.
Blood. 2010.
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KANTARJIAN HM , Giles FJ, Bhalla KN, Pinilla-Ibarz JA, et al
Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase following imatinib resistance or intolerance: 24-month follow-up results.
Blood. 2010.
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GUPTA V , Tallman MS, Weisdorf DJ
Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknowns.
Blood. 2010.
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HOKLAND P , Ommen HB
Towards individualized follow-up in adult acute myeloid leukemia in remission: what is lacking before we can apply minimal residual disease as an integrated tool in clinical decision-making?
Blood. 2010.
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DORNAN D , Spleiss O, Yeh RF, Duchateau-Nguyen G, et al
Effect of FCGR2A and FCGR3A variants on CLL outcome.
Blood. 2010;116:4212-22.
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MESSMER D , Fecteau JF, O'Hayre M, Bharati IS, et al
Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib.
Blood. 2010.
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CHANTEPIE SP , Salaun V, Parienti JJ, Truquet F, et al
Hematogones: a new prognostic factor for acute myeloblastic leukemia.
Blood. 2010.
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EL OMARI K , Hoosdally SJ, Tuladhar K, Karia D, et al
Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex.
Blood. 2010.
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SMITH AE , Mohamedali AM, Kulasekararaj A, Lim Z, et al
Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value.
Blood. 2010;116:3923-32.
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FOX CP , Haigh TA, Taylor GS, Long HM, et al
A novel latent membrane 2 transcript expressed in Epstein-Barr virus-positive NK- and T-cell lymphoproliferative disease encodes a target for cellular immunotherapy.
Blood. 2010;116:3695-704.
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SANT M , Allemani C, Tereanu C, De Angelis R, et al
Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project.
Blood. 2010;116:3724-34.
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KOESTNER W , Hapke M, Herbst J, Klein C, et al
PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host-disease after delayed adoptive transfer of T cell receptor gene-engineered allogeneic CD8+ T cells.
Blood. 2010.
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KARJALAINEN K , Jaalouk DE, Bueso-Ramos CE, Zurita AJ, et al
Targeting neuropilin-1 in human leukemia and lymphoma.
Blood. 2010.
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FEHNIGER TA , Uy GL, Trinkaus K, Nelson AD, et al
A phase II study of high dose lenalidomide as initial therapy for older patients with acute myeloid leukemia.
Blood. 2010.
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TSUKAHARA F , Maru Y
Bag1 directly routes immature BCR-ABL for proteasomal degradation.
Blood. 2010;116:3582-92.
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FIELDING AK
How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia.
Blood. 2010;116:3409-17.
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PILLOZZI S , Masselli M, De Lorenzo E, Accordi B, et al
Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers.
Blood. 2010.
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SHANAFELT TD , Drake MT, Maurer MJ, Allmer C, et al
Vitamin D insufficiency and prognosis in chronic lymphocytic leukemia (CLL).
Blood. 2010.
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KUIPERS JE , Coenen EA, Balgobind BV, Stary J, et al
High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).
Blood. 2010.
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MARCUCCI G , Mrozek K, Radmacher MD, Garzon R, et al
The prognostic and functional role of microRNAs in acute myeloid leukemia.
Blood. 2010.
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October 2010

POSTHUMA HL , Skoda RC, Jacob FA, van der Maas AP, et al
Hereditary thrombocytosis not as innocent as thought? Development into acute leukemia and myelofibrosis.
Blood. 2010;116:3375-6.
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FALINI B , Martelli MP, Bolli N, Sportoletti P, et al
Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?
Blood. 2010.
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JABBOUR E , Kantarjian H, O'Brien S, Shan J, et al
Predictive factors for outcome and response in patients treated with second generation tyrosine kinase inhibitors for chronic myeloid leukemia in chronic phase post imatinib failure.
Blood. 2010.
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WILHELM BT , Briau M, Austin P, Faubert A, et al
RNA-seq analysis of two closely related leukemia clones that differ in their self-renewal capacity.
Blood. 2010.
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CHEN R , Guo L, Chen Y, Jiang Y, et al
Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
Blood. 2010.
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GUO M , Hu KX, Yu CL, Sun QY, et al
Infusion of HLA-mismatched peripheral blood stem cells improves outcome of chemotherapy for acute myeloid leukemia in elderly patients.
Blood. 2010.
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PAVLU J , Szydlo RM, Goldman JM, Apperley JF, et al
Three decades of transplantation for chronic myeloid leukemia: what have we learnt?
Blood. 2010.
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SIGAL DS , Miller HJ, Schram ED, Saven A, et al
Beyond hairy cell: the activity of cladribine in other hematologic malignancies.
Blood. 2010;116:2884-96.
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STARCZYNOWSKI DT , Morin R, McPherson A, Lam J, et al
Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations.
Blood. 2010.
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PASSAMONTI F , Cervantes F, Vannucchi AM, Morra E, et al
Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis.
Blood. 2010;116:2857-8.
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ROSATI E , Sabatini R, Rampino G, De Falco F, et al
Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL.
Blood. 2010;116:2713-23.
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YOKOYAMA T , Kanno Y, Yamazaki Y, Takahara T, et al
Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis.
Blood. 2010;116:2768-75.
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BACHAS C , Schuurhuis GJ, Hollink IH, Kwidama ZJ, et al
High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine.
Blood. 2010;116:2752-8.
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JO SH , Schatz JH, Acquaviva J, Singh H, et al
Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis.
Blood. 2010;116:2759-67.
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HERISHANU Y , Perez-Galan P, Liu D, Biancotto A, et al
The lymph node microenvironment promotes B-cell receptor signaling, NF-{kappa}B activation, and tumor proliferation in chronic lymphocytic leukemia.
Blood. 2010.
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SUCH E , Cervera J, Valencia A, Barragan E, et al
A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia.
Blood. 2010.
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KANAKRY CG , Hess AD, Gocke CD, Thoburn C, et al
Early lymphocyte recovery following intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.
Blood. 2010.
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RUSSWURM G , Heinsch M, Radkowski R, Erlemann R, et al
Dasatinib induces complete remission in a patient with primary cerebral involvement of B-cell chronic lymphocytic leukemia failing chemotherapy.
Blood. 2010;116:2617-8.
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CLARKE WT , Marks PW
Gemtuzumab ozogamicin: is there room for salvage?
Blood. 2010;116:2618-9.
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RAVANDI F , Cortes J, Faderl S, O'Brien S, et al
Characteristics and outcome of patients with acute myeloid leukemia refractory to one cycle of high dose cytarabine-based induction chemotherapy.
Blood. 2010.
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WANG J , Liu Y, Li Z, Du J, et al
Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia.
Blood. 2010.
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September 2010

ISAKSON P , Bjoras M, Boe SO, Simonsen A, et al
Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein.
Blood. 2010;116:2324-31.
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PREBET T , Lhoumeau AC, Arnoulet C, Aulas A, et al
The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome.
Blood. 2010;116:2315-23.
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RAMSINGH G , Koboldt DC, Trissal M, Chiappinelli KB, et al
Complete characterization of the microRNAome in a patient with acute myeloid leukemia.
Blood. 2010.
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JIANG X , Forrest D, Nicolini F, Turhan A, et al
Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
Blood. 2010;116:2112-21.
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TANAKA R , Squires MS, Kimura S, Yokota A, et al
Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL-positive leukemic cells.
Blood. 2010;116:2089-95.
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GRUSZKA AM , Lavorgna S, Consalvo MI, Ottone T, et al
A monoclonal antibody against mutated nucleophosmin 1 for the molecular diagnosis of acute myeloid leukemias.
Blood. 2010;116:2096-102.
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LEAHY MF , Turner JH
Radio-immunotherapy of indolent non-Hodgkin lymphoma with 131I-rituximab in routine clinical practice: 10-year, single institution experience of 142 consecutive patients.
Blood. 2010.
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IMAGAWA J , Harada Y, Shimomura T, Tanaka H, et al
Clinical and genetic features of therapy-related myeloid neoplasms after chemotherapy for acute promyelocytic leukemia.
Blood. 2010.
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XIAO W , Ando T, Wang HY, Kawakami Y, et al
Lyn- and PLC-{beta}3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.
Blood. 2010.
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TALLMAN MS , Kim HT, Montesinos P, Appelbaum FR, et al
Does microgranular variant morphology of acute promyelocytic leukemia independently predict for a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group.
Blood. 2010.
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CHEN J , Petrus M, Bryant BR, Nguyen VP, et al
Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T cell leukemia.
Blood. 2010.
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LUGTHART S , Figueroa ME, Bindels E, Skrabanek L, et al
Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.
Blood. 2010.
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TSAI AG , Yoda A, Weinstock DM, Lieber MR, et al
t(X;14)(p22;q32)/t(Y;14)(p11;q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not.
Blood. 2010;116:1993-4.
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HERR AL , Kabbara N, Bonfim CM, Teira P, et al
Long-term follow-up and factors influencing outcomes after related HLA-identical cord blood transplantation for patients with malignancies: an analysis on behalf of Eurocord-EBMT.
Blood. 2010;116:1849-56.
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LIN TT , Letsolo BT, Jones RE, Rowson J, et al
Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis.
Blood. 2010;116:1899-907.
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SCHWIND S , Marcucci G, Maharry K, Radmacher MD, et al
BAALC and ERG expression levels are associated with outcome and distinct gene- and microRNA-expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
Blood. 2010.
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IBRAHIM AR , Paliompeis C, Bua M, Milojkovic D, et al
Efficacy of tyrosine kinase inhibitors (TKI) as third line therapy in patients with chronic myeloid leukemia in chronic phase who have failed two prior TKI.
Blood. 2010.
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FOON KA
Clearly defined response criteria evaluating treatment of CLL patients in clinical research trials.
Blood. 2010;116:1817.
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KHAN FM , Sy S, Louie P, Ugarte-Torres A, et al
Genomic instability after allogeneic hematopoietic cell transplantation is frequent in oral mucosa, particularly in patients with a history of chronic graft-versus-host disease, and rare in nasal mucosa.
Blood. 2010;116:1803-6.
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PANTULU ND , Pallasch CP, Kurz AK, Kassem A, et al
Detection of a novel truncating Merkel cell polyomavirus large T antigen deletion in chronic lymphocytic leukemia cells.
Blood. 2010.
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FRIEDBICHLER K , Kerenyi MA, Kovacic B, Li G, et al
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.
Blood. 2010;116:1548-58.
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CHIU PP , Jiang H, Dick JE
Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance.
Blood. 2010.
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August 2010

YAMAMOTO Y , Tsuzuki S, Tsuzuki M, Handa K, et al
BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia.
Blood. 2010.
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NAGEL I , Szczepanowski M, Martin-Subero JI, Harder L, et al
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies.
Blood. 2010;116:1317-20.
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CSOMOS K , Nemet I, Fesus L, Balajthy Z, et al
Tissue transglutaminase contributes to the all-trans retinoic acid induced differentiation syndrome phenotype in the NB4 model of acute promyelocytic leukemia.
Blood. 2010.
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LETESTU R , Levy V, Eclache V, Baran-Marszak F, et al
Prognosis of Binet stage A chronic lymphocytic leukemia patients: the strength of routine parameters.
Blood. 2010.
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MORENO C , Hodgson K, Ferrer G, Elena M, et al
Autoimmune cytopenias in chronic lymphocytic leukemia: prevalence, clinical associations, and prognostic significance.
Blood. 2010.
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KANEZAKI R , Toki T, Terui K, Xu G, et al
Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia.
Blood. 2010.
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PARKIN B , Erba H, Ouillette P, Roulston D, et al
Acquired genomic copy number aberrations and survival in adult acute myelogenous leukemia.
Blood. 2010.
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LIU W , Lee HW, Liu Y, Wang R, et al
Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.
Blood. 2010.
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YANG Y , Letard S, Borge L, Chaix A, et al
Pediatric mastocytosis-associated KIT extracellular domain mutations exhibit different functional and signaling properties compared with KIT-phosphotransferase domain mutations.
Blood. 2010;116:1114-23.
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KONDO A , Yamashita T, Tamura H, Zhao W, et al
Interferon-gamma and tumor necrosis factor-alpha induce an immunoinhibitory molecule, B7-H1, via nuclear factor-kappaB activation in blasts in myelodysplastic syndromes.
Blood. 2010;116:1124-31.
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BALAKRISHNAN K , Burger JA, Quiroga MP, Henneberg M, et al
Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells.
Blood. 2010;116:1083-91.
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RIZO A , Horton SJ, Olthof S, Dontje B, et al
BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells.
Blood. 2010.
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MOHTY M , Labopin M, Volin L, Gratwohl A, et al
Reduced-intensity versus conventional myeloablative conditioning allogeneic stem cell transplantation for patients with acute lymphoblastic leukemia: a retrospective study from the European Group for Blood and Marrow Transplantation.
Blood. 2010.
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CRIPE LD , Uno H, Paietta EM, Litzow MR, et al
Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled, trial of the Eastern Cooperative Oncology Group (ECOG 3999).
Blood. 2010.
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STEELE AJ , Prentice AG, Cwynarski K, Hoffbrand AV, et al
The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.
Blood. 2010.
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WU SJ , Huang SY, Lin CT, Lin YJ, et al
The incidence of chronic lymphocytic leukemia in Taiwan, 1986-2005: a distinct, increasing trend with birth-cohort effect.
Blood. 2010.
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KUWABARA A , Babb A, Ibrahim A, Milojkovic D, et al
Poor outcome after reintroduction of imatinib in patients with chronic myeloid leukemia who interrupt therapy on account of pregnancy without having achieved an optimal response.
Blood. 2010;116:1014-6.
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MOORMAN AV , Chilton L, Wilkinson J, Ensor HM, et al
Response: Age- and sex-adjusted incidence rates of adults with acute lymphoblastic leukemia (ALL) in the northern part of England.
Blood. 2010;116:1012.
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JULIUSSON G , Karlsson K, Hallbook H
Population-based analyses in adult acute lymphoblastic leukemia.
Blood. 2010;116:1011.
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POWELL BL , Moser B, Stock W, Gallagher RE, et al
Arsenic trioxide improves event-free and over-all survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710.
Blood. 2010.
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HIROSE K , Inukai T, Kikuchi J, Furukawa Y, et al
Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).
Blood. 2010;116:962-70.
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ROSSI S , Shimizu M, Barbarotto E, Nicoloso MS, et al
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival.
Blood. 2010;116:945-52.
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HARVEY RC , Mullighan CG, Wang X, Dobbin KK, et al
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome.
Blood. 2010.
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CHOU WC , Huang HH, Hou HA, Chen CY, et al
Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations.
Blood. 2010.
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OHTAKE S , Miyawaki S, Fujita H, Kiyoi H, et al
Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: JALSG AML201 Study.
Blood. 2010.
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VALENT P , Arock M, Akin C, Sperr WR, et al
The classification of systemic mastocytosis should include mast cell leukemia (MCL) and systemic mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD).
Blood. 2010;116:850-1.
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LIU X , Ryland L, Yang J, Liao A, et al
Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia.
Blood. 2010.
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HUGHES TP , Hochhaus A, Branford S, Muller MC, et al
Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the international randomized study of interferon versus STI571 (IRIS).
Blood. 2010.
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KORNBLAU SM , McCue D, Singh N, Chen W, et al
Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia.
Blood. 2010.
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July 2010

SHAW PJ , Kan F, Ahn KW, Spellman SR, et al
Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related or matched unrelated donors.
Blood. 2010.
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CHAPUIS N , Park S, Leotoing L, Tamburini J, et al
I{kappa}B kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia.
Blood. 2010.
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COCCO C , Canale S, Frasson C, Di Carlo E, et al
Interleukin (IL)-23 acts as anti-tumor agent on childhood B-acute lymphoblastic leukemia cells.
Blood. 2010.
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WICHMANN C , Becker Y, Chen-Wichmann L, Vogel V, et al
Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity.
Blood. 2010;116:603-13.
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KANTARJIAN H , Ravandi F, O'Brien S, Cortes J, et al
Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia.
Blood. 2010.
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GREEN AS , Chapuis N, Maciel TT, Willems L, et al
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.
Blood. 2010.
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THEPOT S , Itzykson R, Seegers V, Raffoux E, et al
Treatment of progression of Philadelphia negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies.
Blood. 2010.
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NISHIWAKI S , Inamoto Y, Sakamaki H, Kurokawa M, et al
Allogeneic stem cell transplantation for adult Philadelphia chromosome-negative acute lymphocytic leukemia: comparable survival rates but different risk factors between related and unrelated transplantation in first complete remission.
Blood. 2010.
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SANTIDRIAN AF , Gonzalez-Girones DM, Iglesias-Serret D, Coll-Mulet L, et al
AICAR induces apoptosis independently of AMPK and p53 through upregulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.
Blood. 2010.
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SEIFFERT M , Schulz A, Ohl S, Dohner H, et al
Soluble CD14 is a novel monocyte-derived survival factor for chronic lymphocytic leukemia cells, which is induced by CLL cells in vitro, and present at abnormally high levels in vivo.
Blood. 2010.
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WHITMAN SP , Maharry K, Radmacher MD, Becker H, et al
FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
Blood. 2010.
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GREEN CL , Evans CM, Hills RK, Burnett AK, et al
The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status.
Blood. 2010.
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LEVY C , Frecha C, Costa C, Rachinel N, et al
Lentiviral vectors and transduction of human cancer B cells.
Blood. 2010;116:498-500.
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CHOU WC , Huang YN, Huang CF, Tseng MH, et al
A single-tube, sensitive multiplex method for screening of isocitrate dehydrogenase 1 (IDH1) mutations.
Blood. 2010;116:495-6.
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LAKHANPAL GK , Vecchiarelli-Federico LM, Li YJ, Cui JW, et al
The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis.
Blood. 2010;116:428-36.
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MARTINS LR , Lucio P, Silva MC, Anderes KL, et al
Targeting CK2 overexpression and hyperactivation as a novel therapeutic tool in chronic lymphocytic leukemia.
Blood. 2010.
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VALERI VW , Hryniewicz A, Andresen V, Jones K, et al
Requirement of the human T-cell leukemia virus p12 and p30 genes for infectivity of human dendritic cells and macaques but not rabbits.
Blood. 2010.
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UY GL , Lane AA, Welch JS, Grieselhuber NR, et al
A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemia.
Blood. 2010.
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BACHMANN PS , Piazza RG, Janes ME, Wong NC, et al
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.
Blood. 2010.
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LO-COCO F , Avvisati G, Vignetti M, Breccia M, et al
Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults patients younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group.
Blood. 2010.
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SHARMEEN S , Skrtic M, Sukhai MA, Hurren R, et al
The anti-parasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells.
Blood. 2010.
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MARTELLI MP , Pettirossi V, Thiede C, Bonifacio E, et al
CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice.
Blood. 2010.
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ENGLER JR , Frede A, Saunders V, Zannettino A, et al
The poor response to imatinib observed in CML patients with low OCT-1 activity is not attributable to lower uptake of imatinib into their CD34+ cells.
Blood. 2010.
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LIEDTKE M , Ayton PM, Somervaille TC, Smith KS, et al
Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6.
Blood. 2010;116:63-70.
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HERTLEIN E , Wagner AJ, Jones J, Lin TS, et al
17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition.
Blood. 2010;116:45-53.
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NOVELLI EM , Redner RL
Knee pain: ACL, MCL, or CML?
Blood. 2010;115:5287.
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BENITA Y , Cao Z, Giallourakis C, Li C, et al
Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor.
Blood. 2010;115:5376-84.
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June 2010

FU CT , Zhu KY, Mi JQ, Liu YF, et al
An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 axis controls myeloid development and transformation.
Blood. 2010;115:4715-24.
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April 2010

SENGUPTA A , Arnett J, Dunn S, Williams DA, et al
Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.
Blood. 2010.
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