: The AMEDEO Literature Guide

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Leukemia

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Articles published in Blood
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February 2010

COGHILL JM , Carlson MJ, Panoskaltsis-Mortari A, West ML, et al
Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells.
Blood. 2010.
PubMed Text format Related articles Abstract available

LIU FT , Giustiniani J, Farren T, Jia L, et al
CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia.
Blood. 2010.
PubMed Text format Related articles Abstract available

CONTER V , Bartram CR, Valsecchi MG, Schrauder A, et al
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study.
Blood. 2010.
PubMed Text format Related articles Abstract available

HARVEY RC , Mullighan CG, Chen IM, Wharton W, et al
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia.
Blood. 2010.
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RASI S , Forconi F, Bruscaggin A, Sozzi E, et al
Impact of the host genetic background on prognosis of chronic lymphocytic leukemia.
Blood. 2010;115:1106-7.
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GUTIERREZ A , Sanda T, Ma W, Zhang J, et al
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia.
Blood. 2010.
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BANERJEE P , Tripp A, Lairmore MD, Crawford L, et al
Adult T cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice.
Blood. 2010.
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STORK LC , Matloub Y, Broxson E, La M, et al
Oral 6-mercaptopurine vs. Oral 6-thioguanine and veno-occlusive disease in children with standard risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial.
Blood. 2010.
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VILLALOBOS IB , Takahashi Y, Akatsuka Y, Muramatsu H, et al
Relapse of leukemia with loss of mismatched HLA due to uniparental disomy following haploidentical hematopoietic stem cell transplantation.
Blood. 2010.
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January 2010

WILOP S , Galm O, Thompson L, Osieka R, et al
Friday leukemia: myth or reality?
Blood. 2010;115:912.
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CHU CC , Catera R, Zhang L, Didier S, et al
Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed non-muscle myosin heavy chain IIA: implications for patient outcome and cell of origin.
Blood. 2010.
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LIGHTFOOT TJ , Johnston WT, Painter D, Simpson J, et al
Genetic variation in the folate metabolic pathway and risk of childhood leukemia.
Blood. 2010.
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LANCA T , Correia DV, Moita CF, Raquel H, et al
The MHC class Ib protein ULBP1 is a non-redundant determinant of leukemia/ lymphoma susceptibility to {gamma}{delta} T-cell cytotoxicity.
Blood. 2010.
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CHOU WC , Hou HA, Chen CY, Tang JL, et al
Distinct clinical and biological characteristics in adult acute myeloid leukemia bearing isocitrate dehydrogenase 1 (IDH1) mutation.
Blood. 2010.
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WANDT H , Haferlach T, Thiede C, Ehninger G, et al
WHO classification of myeloid neoplasms and leukemia.
Blood. 2010;115:748-9.
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QIU JJ , Lu X, Zeisig BB, Ma Z, et al
Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}.
Blood. 2010;115:643-52.
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ASSLABER D , Pinon JD, Seyfried I, Desch P, et al
MicroRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Blood. 2010.
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KHANDANPOUR C , Thiede C, Valk PJ, Sharif-Askari E, et al
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia.
Blood. 2010.
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DEISSEROTH A , Farrell A, Justice R, Kane R, et al
Toxicity of laromustine plus high-dose cytarabine in patients with relapsed acute myeloid leukemia.
Blood. 2010;115:430.
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XU GW , Ali M, Wood TE, Wong D, et al
The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.
Blood. 2010.
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TANJI H , Ishikawa C, Sawada S, Nakachi S, et al
Aberrant expression of the transcription factor Twist in adult T-cell leukemia.
Blood. 2010.
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WARREN EH , Fujii N, Akatsuka Y, Chaney CN, et al
Therapy of relapsed leukemia after allogeneic hematopoietic cell transplant with T cells specific for minor histocompatibility antigens.
Blood. 2010.
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HEANEY NB , Pellicano F, Zhang B, Crawford L, et al
Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells.
Blood. 2010.
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KUEHNL A , Goekbuget N, Stroux A, Burmeister T, et al
High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia.
Blood. 2010.
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CAPITANI N , Lucherini OM, Sozzi E, Ferro M, et al
Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia.
Blood. 2010.
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KUANG SQ , Bai H, Fang ZH, Lopez G, et al
Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia.
Blood. 2010.
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SAWADA S , Ishikawa C, Tanji H, Nakachi S, et al
Overexpression of caveolin-1 in adult T-cell leukemia.
Blood. 2010.
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SMITH AC , Raimondi AR, Salthouse CD, Ignatius MS, et al
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.
Blood. 2010.
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SIGAL DS , Sharpe R, Burian C, Saven A, et al
Very long-term eradication of minimal residual disease in patients with hairy cell leukemia following a single course of cladribine.
Blood. 2010.
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TAUSSIG DC , Vargaftig J, Miraki-Moud F, Griessinger E, et al
Leukemia initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34- fraction.
Blood. 2010.
PubMed Text format Related articles Abstract available

December 2009

PRASAD RB , Hosking FJ, Vijayakrishnan J, Papaemmanuil E, et al
Verification of the susceptibility loci on 7p12.2, 10q21.2 and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood.
Blood. 2009.
PubMed Text format Related articles Abstract available

DYER MJ , Akasaka T, Capasso M, Dusanjh P, et al
Immunoglobulin heavy chain (IGH) locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL): rare clinical curios or potent genetic drivers?
Blood. 2009.
PubMed Text format Related articles Abstract available

KLINGEBIEL T , Cornish J, Labopin M, Locatelli F, et al
Results and factors influencing outcome after fully haploidentical hematopoietic stem cell transplant in children with very-high risk acute lymphoblastic leukemia - impact of center size: an analysis on behalf of the Acute Leukemia and Pediatric Disea
Blood. 2009.
PubMed Text format Related articles Abstract available

HASSERJIAN RP , Zuo Z, Garcia C, Tang G, et al
Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification.
Blood. 2009.
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STAM RW , Schneider P, Hagelstein JA, van der Linden MH, et al
Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants.
Blood. 2009.
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LITZOW MR , Tarima S, Perez WS, Bolwell BJ, et al
Allogeneic transplantation for therapy-related myelodysplastic syndrome and acute myeloid leukemia.
Blood. 2009.
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ZHOU J , Zhang Y, Li J, Li X, et al
Single-agent arsenic trioxide in the treatment of children with newly diagnosed acute promyelocytic leukemia.
Blood. 2009.
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PULIKKAN JA , Dengler V, Paramangalam PS, Peer Zada AA, et al
Cell cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia.
Blood. 2009.
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BRUGGEMANN M , Trautmann H, Hoelzer D, Kneba M, et al
Multidrug resistance-associated protein 4 (MRP4) gene polymorphisms and treatment response in adult acute lymphoblastic leukemia.
Blood. 2009;114:5400-1.
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GHOSH AK , Secreto CR, Knox TR, Ding W, et al
Circulating microvesicles in B cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression.
Blood. 2009.
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ADES L , Guerci A, Raffoux E, Sanz M, et al
Very long-term outcome of acute promyelocytic leukemia after treatment wtih all trans retinoic acid and chemotherapy: the European APL Group experience.
Blood. 2009.
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BAESSLER T , Charton JE, Schmiedel BJ, Grunebach F, et al
CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK cell reactivity against human acute myeloid leukemia cells.
Blood. 2009.
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KHARAS MG , Okabe R, Ganis JJ, Gozo M, et al
Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice.
Blood. 2009.
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MURAMATSU H , Makishima H, Jankowska AM, Cazzolli H, et al
Mutations of E3 ubiquitin ligase Cbl family members but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia.
Blood. 2009.
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SILVERMAN LB , Supko JG, Stevenson KE, Woodward C, et al
Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia.
Blood. 2009.
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RIVA G , Luppi M, Barozzi P, Quadrelli C, et al
Emergence of BCR-ABL-specific cytotoxic T cells in the bone marrow of patients with Ph+ acute lymphoblastic leukemia during long-term Imatinib mesylate treatment.
Blood. 2009.
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SANDA T , Li X, Gutierrez A, Ahn Y, et al
Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia.
Blood. 2009.
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STAM RW , Den Boer ML, Schneider P, de Boer J, et al
Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia.
Blood. 2009.
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Blast crisis.
Blood. 2009;114:4917.
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NOWAK D , Ogawa S, Muschen M, Kato M, et al
SNP array analysis of tyrosine kinase inhibitor (TKI) resistant chronic myeloid leukemia (CML) identifies heterogeneous secondary genomic alterations.
Blood. 2009.
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AWAN FT , Lapalombella R, Trotta R, Butchar JP, et al
CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain engineered monoclonal antibody.
Blood. 2009.
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November 2009

MILANI L , Lundmark A, Kiialainen A, Nordlund J, et al
DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia.
Blood. 2009.
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HERTZBERG L , Vendramini E, Ganmore I, Cazzaniga G, et al
Down syndrome acute lymphoblastic leukemia: a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the iBFM Study Group.
Blood. 2009.
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LIN YW , Beharry ZM, Hill EG, Song JH, et al
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.
Blood. 2009.
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CALIGARIS-CAPPIO F
IG genes and hairy cell leukemia.
Blood. 2009;114:4610-1.
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FURUGAKI K , Pokorna K, le Pogam C, Aoki M, et al
DNA vaccination with all-trans retinoic acid treatment induces long term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model.
Blood. 2009.
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UGARTE-BERZAL E , Redondo-Munoz J, Eroles P, Hernandez Del Cerro M, et al
VEGF/VEGFR2 interaction downregulates matrix metalloproteinase-9 via STAT1 activation and inhibits B chronic lymphocytic leukemia cell migration.
Blood. 2009.
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SAUSSELE S , Lauseker M, Gratwohl A, Beelen DW, et al
Allogeneic hematopoietic stem cell transplantation (alloSCT) for chronic myeloid leukemia in the imatinib era; evaluation of its impact within a subgroup of the randomized German CML Study IV.
Blood. 2009.
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PENG C , Chen Y, Yang Z, Zhang H, et al
PTEN is a tumor suppressor in CML stem cells and BCR-ABL induced leukemias in mice.
Blood. 2009.
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FRIEDBERG JW , Sharman J, Sweetenham J, Johnston PB, et al
Inhibition of Syk with fostamatinib disodium has significant clinical activity in non Hodgkin's lymphoma and chronic lymphocytic leukemia.
Blood. 2009.
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CRISTOBAL I , Blanco FJ, Garcia-Orti L, Marcotegui N, et al
SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemia.
Blood. 2009.
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MICOL JB , Boissel N, Renneville A, Castaigne S, et al
The role of cytogenetic abnormalities in acute myeloid leukemia with NPM1 mutations and no FLT3 internal tandem duplication.
Blood. 2009;114:4601-2.
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BURNETT AK , Hills RK, Green C, Jenkinson S, et al
The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with non-acute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3 a
Blood. 2009.
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BULLINGER L , Ehrich M, Dohner K, Schlenk RF, et al
Quantitative DNA-methylation predicts survival in adult acute myeloid leukemia.
Blood. 2009.
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KANDURI M , Cahill N, Goransson H, Enstrom C, et al
Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia.
Blood. 2009.
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BOUAZIZ JD , Cordel N, Hickman G, Fieschi C, et al
Cutaneous tumor lysis syndrome in a patient with HTLV-1 adult T-cell lymphoma/leukemia.
Blood. 2009;114:4320-1.
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RAVID K
MAL: not just a leukemia inducer.
Blood. 2009;114:3977-8.
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MAYS AN , Osheroff N, Xiao Y, Wiemels JL, et al
Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia.
Blood. 2009.
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October 2009

BRANFORD S , Melo JV, Hughes TP
Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure - does the BCR-ABL mutation status really matter?
Blood. 2009.
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KANG H , Chen IM, Wilson CS, Bedrick EJ, et al
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia.
Blood. 2009.
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DOHNER H , Estey EH, Amadori S, Appelbaum FR, et al
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel,on behalf of the European LeukemiaNet.
Blood. 2009.
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KALOTA A , Gewirtz AM
A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells.
Blood. 2009.
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JAMES SE , Orgun NN, Tedder TF, Shlomchik MJ, et al
Antibody mediated B cell depletion prior to adoptive immunotherapy with T cells expressing CD20-specific chimeric T cell receptors facilitates eradication of leukemia in immunocompetent mice.
Blood. 2009.
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DROIN N , Jacquel A, Hendra JB, Racoeur C, et al
Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.
Blood. 2009.
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NAKAHARA F , Sakata-Yanagimoto M, Komeno Y, Kato N, et al
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.
Blood. 2009.
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FISHER CL , Pineault N, Brookes C, Helgason CD, et al
Loss-of-function Additional sex combs-like1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia.
Blood. 2009.
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LEMOLI RM , Salvestrini V, Bianchi E, Bertolini F, et al
Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib.
Blood. 2009.
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STUMPEL DJ , Schneider P, van Roon EH, Boer JM, et al
Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options.
Blood. 2009.
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GARZON R , Heaphy CE, Havelange V, Fabbri M, et al
MicroRNA 29b functions in acute myeloid leukemia.
Blood. 2009.
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MALCIKOVA J , Smardova J, Rocnova L, Tichy B, et al
Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival and response to DNA damage.
Blood. 2009.
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BYRD JC , Kipps TJ, Flinn IW, Castro J, et al
Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia.
Blood. 2009.
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NICOLINI FE , Mauro MJ, Martinelli G, Kim DW, et al
Epidemiological study on survival of chronic myeloid leukemia (CML) and Ph+ acute lymphoblastic leukemia (ALL) patients with BCR-ABL T315I mutation.
Blood. 2009.
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GREVER MR
How I treat hairy cell leukemia.
Blood. 2009.
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MCWEENEY SK , Pemberton LC, Loriaux MM, Vartanian K, et al
A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic phase chronic myeloid leukemia patients treated with imatinib.
Blood. 2009.
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PARDANANI A , Tefferi A, Litzow MR, Zent C, et al
Chronic myeloid leukemia with p190BCR-ABL: prevalence, morphology, tyrosine kinase inhibitor response, and kinase domain mutation analysis.
Blood. 2009;114:3502-3.
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MARKS DI , Paietta EM, Moorman AV, Richards SM, et al
T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics and outcome from the large randomised prospective trial (UKALL XII/ECOG 2993).
Blood. 2009.
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TSAI HT , Caporaso NE, Kyle RA, Katzmann JA, et al
Evidence of serum immunoglobulin abnormalities up to 9.8 years prior to diagnosis of chronic lymphocytic leukemia: a prospective study.
Blood. 2009.
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LUESINK M , Pennings JL, Wissink WM, Linssen PC, et al
Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia - triggering the differentiation syndrome.
Blood. 2009.
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TRINIDAD EM , Ballesteros M, Zuloaga J, Zapata A, et al
An impaired transendothelial migration potential of chronic lymphocytic leukemia cells can be linked to ephrin-A4 expression.
Blood. 2009.
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ABBOTT LS , Deevska M, Fernandez CV, Dix D, et al
The impact of prophylactic fresh frozen plasma and cryoprecipitate on the incidence of CNS thrombosis and hemorrhage in children with acute lymphoblastic leukemia receiving asparaginase.
Blood. 2009.
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ROSTI G , Palandri F, Castagnetti F, Breccia M, et al
Nilotinib for the frontline treatment of Ph+ chronic myeloid leukemia.
Blood. 2009.
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KROGER N , Holler E, Kobbe G, Bornhaeuser M, et al
Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT).
Blood. 2009.
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CROWTHER-SWANEPOEL D , Qureshi M, Dyer MJ, Matutes E, et al
Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia.
Blood. 2009.
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YOSHIMOTO G , Miyamoto T, Jabbarzadeh-Tabrizi S, Iino T, et al
FLT3-ITD upregulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation.
Blood. 2009.
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TANG JL , Hou HA, Chen CY, Liu CY, et al
AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.
Blood. 2009.
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STONE RM , DeAngelo DJ
Screens, iron, and leukemia.
Blood. 2009;114:2857-8.
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GUIBAL FC , Alberich-Jorda M, Hirai H, Ebralidze A, et al
Identification of a myeloid committed progenitor as the cancer initiating cell in acute promyelocytic leukemia.
Blood. 2009.
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TALLMAN MS , Altman JK
How I treat acute promyelocytic leukemia.
Blood. 2009.
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TESTONI N , Marzocchi G, Luatti S, Amabile M, et al
Chronic myeloid leukemia: a prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response, a study of the GIMEMA CML WP.
Blood. 2009.
PubMed Text format Related articles Abstract available

September 2009

CALISSANO C , Damle RN, Hayes G, Murphy EJ, et al
In vivo intra- and inter-clonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia.
Blood. 2009.
PubMed Text format Related articles Abstract available

COSTANTINI JL , Cheung SM, Hou S, Li H, et al
TAPP2 links phosphoinositide 3-kinase signaling to B cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B cell leukemia.
Blood. 2009.
PubMed Text format Related articles Abstract available

PAGEL JM , Gooley TA, Rajendran J, Fisher DR, et al
Allogeneic hematopoietic cell transplantation after conditioning with 131I-anti-CD45 antibody plus fludarabine and low-dose total body irradiation for elderly patients with advanced acute myeloid leukemia or high-risk myelodysplastic syndrome.
Blood. 2009.
PubMed Text format Related articles Abstract available

DEL GIUDICE I , Mauro FR, De Propris MS, Starza ID, et al
Identification of monoclonal B-cell lymphocytosis among sibling transplant donors for chronic lymphocytic leukemia patients.
Blood. 2009;114:2848-9.
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MULLER MC , Cortes JE, Kim DW, Druker BJ, et al
Dasatinib treatment of chronic phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations.
Blood. 2009.
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RAHMANI M , Anderson A, Habibi JR, Crabtree TR, et al
The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways.
Blood. 2009.
PubMed Text format Related articles Abstract available

HERLING M , Patel KA, Weit N, Lilienthal N, et al
High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia.
Blood. 2009.
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BURGER JA , Gandhi V
The lymphatic tissue microenvironments in chronic lymphocytic leukemia: in vitro models and the significance of CD40-CD154 interactions.
Blood. 2009;114:2560-1.
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KAYSER S , Schlenk RF, Londono MC, Breitenbuecher F, et al
Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome.
Blood. 2009;114:2386-92.
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SCHWIEGER M , Schuler A, Forster M, Engelmann A, et al
Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C.
Blood. 2009;114:2476-88.
PubMed Text format Related articles Abstract available

VOLANAKIS EJ , Williams RT, Sherr CJ
Stage-specific Arf tumor suppression in Notch1-induced T cell acute lymphoblastic leukemia.
Blood. 2009.
PubMed Text format Related articles Abstract available

LI Z , Zhang W, Wu M, Zhu S, et al
Gene expression-based classification and regulatory networks of pediatric acute lymphoblastic leukemia.
Blood. 2009.
PubMed Text format Related articles Abstract available

ENZLER T , Kater AP, Zhang W, Widhopf GF 2nd, et al
Chronic lymphocytic leukemia of E{micro}-TCL1 transgenic mice undergoes rapid cell-turnover that can be offset by extrinsic CD257 to accelerate disease progression.
Blood. 2009.
PubMed Text format Related articles Abstract available

KOTANI A , Ha D, Hsieh J, Rao PK, et al
miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221.
Blood. 2009.
PubMed Text format Related articles Abstract available

ARONS E , Suntum T, Stetler-Stevenson M, Kreitman RJ, et al
VH4-34+ hairy cell leukemia, a new variant with poor prognosis despite standard therapy.
Blood. 2009.
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SHARMA S , Lichtenstein A
Aberrant splicing of the E-cadherin transcript is a novel mechanism of gene silencing in chronic lymphocytic leukemia cells.
Blood. 2009.
PubMed Text format Related articles Abstract available

CALIN GA , Croce CM
Chronic lymphocytic leukemia: interplay between non-coding RNAs and protein-coding genes.
Blood. 2009.
PubMed Text format Related articles Abstract available

SCHNITTGER S , Kern W, Tschulik C, Weiss T, et al
Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML.
Blood. 2009;114:2220-31.
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IACOBUCCI I , Storlazzi CT, Cilloni D, Lonetti A, et al
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leuk
Blood. 2009;114:2159-67.
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SOVERINI S , Gnani A, Colarossi S, Castagnetti F, et al
Philadelphia-positive patients who already harbor imatinib-resistant Bcr-Abl kinase domain mutations have a higher likelihood of developing additional mutations associated with resistance to second- or third-line tyrosine kinase inhibitors.
Blood. 2009;114:2168-71.
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ZHOU Q , Bucher C, Munger ME, Highfill SL, et al
Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T cell immunotherapy in murine acute myeloid leukemia.
Blood. 2009.
PubMed Text format Related articles Abstract available

August 2009

VISONE R , Rassenti LZ, Veronese A, Taccioli C, et al
Karyotype specific microRNA signature in chronic lymphocytic leukemia.
Blood. 2009.
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SUTTON LA , Kostareli E, Hadzidimitriou A, Darzentas N, et al
Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen.
Blood. 2009.
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USENKO T , Li YJ, Haeri M, Li Y, et al
Enrichment of Sca1+ hematopoietic progenitors in polycythemic mice inhibits leukemogenesis.
Blood. 2009;114:1831-41.
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CUTTS BA , Sjogren AK, Andersson KM, Wahlstrom AM, et al
Nf1 deficiency co-operates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Blood. 2009.
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WILL B , Kawahara M, Luciano JP, Bruns I, et al
Effect of the non-peptide thrombopoietin receptor agonist eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome.
Blood. 2009.
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GILES F , Vey N, Deangelo D, Seiter K, et al
Phase III randomized, placebo-controlled, double-blind study of high dose continuous infusion cytarabine alone or with laromustine (VNP40101M) in patients with acute myeloid leukemia in first relapse.
Blood. 2009.
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VERNERIS MR , Brunstein CG, Barker J, Macmillan ML, et al
Relapse risk after umbilical cord blood transplantation: enhanced graft versus leukemia effect in recipients of two units.
Blood. 2009.
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PALLASCH CP , Patz M, Park YJ, Hagist S, et al
miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.
Blood. 2009.
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SEILER T , Woelfle M, Yancopoulos S, Catera R, et al
Characterization of structurally-defined epitopes recognized by monoclonal antibodies produced by chronic lymphocytic leukemia B cells.
Blood. 2009.
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COSTINEAN S , Sandhu SK, Pedersen IM, Tili E, et al
Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice.
Blood. 2009;114:1374-82.
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HERCUS TR , Thomas D, Guthridge MA, Ekert PG, et al
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.
Blood. 2009;114:1289-98.
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FRECHA C , Costa C, Levy C, Negre D, et al
Efficient and stable transduction of resting B-lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors.
Blood. 2009.
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BASKAR S , Suschak JM, Samija I, Srinivasan R, et al
A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display.
Blood. 2009.
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HEUSER M , Sly LM, Argiropoulos B, Kuchenbauer F, et al
Modelling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal.
Blood. 2009.
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SILVA FP , Swagemakers SM, Erpelinck-Verschueren C, Wouters BJ, et al
Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status.
Blood. 2009.
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RADICH JP
How I monitor residual disease in chronic myeloid leukemia.
Blood. 2009.
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GREEN DJ , Pagel JM, Nemecek ER, Lin Y, et al
Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates.
Blood. 2009;114:1226-35.
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VAN DER LINDEN MH , Valsecchi MG, De Lorenzo P, Moricke A, et al
Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.
Blood. 2009.
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ZARRINKAR PP , Gunawardane RN, Cramer MD, Gardner MF, et al
AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).
Blood. 2009.
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OEHLER VG , Yeung KY, Choi YE, Bumgarner RE, et al
The derivation of diagnostic markers of chronic myeloid leukemia progression from microarray data.
Blood. 2009.
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HU X , Shen H, Tian C, Yu H, et al
Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model.
Blood. 2009.
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July 2009

PASMANT E , Ballerini P, Lapillonne H, Perot C, et al
SPRED1 disorder and predisposition to leukemia in children.
Blood. 2009;114:1131.
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LINGER RM , Deryckere D, Brandao L, Sawczyn KK, et al
Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia.
Blood. 2009.
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TANG R , Hirsch P, Fava F, Lapusan S, et al
High Id1 expression is associated with poor prognosis in 237 patients with acute myeloid leukemia.
Blood. 2009.
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TOSELLO V , Mansour MR, Barnes K, Paganin M, et al
WT1 mutations in T-ALL.
Blood. 2009;114:1038-45.
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MILLS KI , Kohlmann A, Williams PM, Wieczorek L, et al
Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome.
Blood. 2009;114:1063-72.
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MOLTENI R , Crespo CL, Feigelson S, Moser C, et al
Beta-arrestin 2 is required for the induction and strengthening of integrin-mediated leukocyte adhesion during CXCR2-driven extravasation.
Blood. 2009;114:1073-82.
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REMKE M , Pfister S, Kox C, Toedt G, et al
High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response.
Blood. 2009;114:1053-62.
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RUSSELL LJ , Capasso M, Vater I, Akasaka T, et al
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B cell precursor acute lymphoblastic leukemia.
Blood. 2009.
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DELGADO J , Milligan DW, Dreger P
Allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia: ready for primetime?
Blood. 2009.
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YAMANAKA Y , Tagawa H, Takahashi N, Watanabe A, et al
Aberrant overexpression of microRNAs activate AKT signaling via downregulation of tumor suppressors in NK-cell lymphoma/leukemia.
Blood. 2009.
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EDWARDS H , Xie C, Lafiura KM, Dombkowski AA, et al
RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia.
Blood. 2009.
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STEFANIDAKIS M , Karjalainen K, Jaalouk DE, Gahmberg CG, et al
Role of leukemia cell invadosome in extramedullary infiltration.
Blood. 2009.
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SEIF AE , Barrett DM, Milone M, Brown VI, et al
Long-term protection from syngeneic acute lymphoblastic leukemia by CpG ODN-mediated stimulation of innate and adaptive immune responses.
Blood. 2009.
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HEUSER M , Kuchenbauer F, Argiropoulos B, Sekulovic S, et al
Priming reloaded?
Blood. 2009;114:925-6.
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PRESS RD , Willis SG, Laudadio J, Mauro MJ, et al
Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib.
Blood. 2009.
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NADERI EH , Findley HW, Ruud E, Blomhoff HK, et al
Activation of cAMP signaling inhibits DNA damage-induced apoptosis in BCP-ALL cells through abrogation of p53 accumulation.
Blood. 2009;114:608-18.
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LIN YH , Kakadia PM, Chen Y, Li YQ, et al
Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.
Blood. 2009;114:651-8.
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EICHHORST BF , Busch R, Stilgenbauer S, Stauch M, et al
First line therapy with fludarabine compared to chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemia.
Blood. 2009.
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HALIN M , Douceron E, Clerc I, Journo C, et al
Human T-cell leukemia virus type 2 produces a spliced antisense transcript encoding a protein that lacks a classical bZIP domain but still inhibits Tax2-mediated transcription.
Blood. 2009.
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THOLOULI E , Watt S, Lucas GS, Burthem J, et al
Stage IV adult sporadic Burkitt lymphoma/leukemia with complex bone marrow cytogenetics is associated with a very poor outcome.
Blood. 2009;114:485-6.
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EBERHARD Y , McDermott S, Wang X, Gronda M, et al
Chelation of intracellular iron with the anti-fungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.
Blood. 2009.
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ASSOULINE S , Culjkovic B, Cocolakis E, Rousseau C, et al
Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin.
Blood. 2009;114:257-60.
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YAMAZAKI J , Mizukami T, Takizawa K, Kuramitsu M, et al
Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T- cell leukemia / lymphoma (ATL).
Blood. 2009.
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Granulocytic sarcoma.
Blood. 2009;114:5.
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NIETO WG , Almeida J, Romero A, Teodosio C, et al
Increased frequency (12%) of circulating chronic lymphocytic leukemia-like B-cell clones in healthy subjects using a highly sensitive multicolor flow cytometry approach.
Blood. 2009;114:33-7.
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ABDEL-WAHAB O , Mullally A, Hedvat C, Garcia-Manero G, et al
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.
Blood. 2009;114:144-7.
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DAGKLIS A , Fazi C, Sala C, Cantarelli V, et al
The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring.
Blood. 2009;114:26-32.
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LOH ML , Sakai DS, Flotho C, Kang M, et al
Mutations in CBL occur frequently in juvenile myelomonocytic leukemia.
Blood. 2009.
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June 2009

JABBOUR E , Jones D, Kantarjian HM, O'Brien S, et al
Long-term outcome of patients with chronic myeloid leukemia treated with second generation tyrosine kinase inhibitors after imatinib failure is predicted by the in vitro sensitivity of BCR-ABL kinase domain mutations.
Blood. 2009.
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BORRELLO IM , Levitsky HI, Stock W, Sher D, et al
GM-CSF secreting cellular immunotherapy in combination with autologous stem cell transplant (ASCT) as post-remission therapy for acute myeloid leukemia (AML).
Blood. 2009.
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CHUK MK , McIntyre E, Small D, Brown P, et al
Discordance of MLL-rearranged (MLL-R) infant acute lymphoblastic leukemia in monozygotic twins with spontaneous clearance of preleukemic clone in unaffected twin.
Blood. 2009;113:6691-4.
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KEILHOLZ U , Letsch A, Busse A, Asemissen AM, et al
A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS.
Blood. 2009;113:6541-8.
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HO PA , Alonzo TA, Gerbing RB, Pollard J, et al
Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group.
Blood. 2009;113:6558-66.
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RIZO A , Olthof S, Han L, Vellenga E, et al
Repression of BMI1 in normal and leukemic human CD34+ cells impairs self-renewal and induces apoptosis.
Blood. 2009.
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ABRISQUETA P , Pereira A, Rozman C, Aymerich M, et al
Improving survival in patients with chronic lymphocytic leukemia (1980-2008): the Hospital Clinic of Barcelona experience.
Blood. 2009.
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KADAN-LOTTICK NS , Brouwers P, Breiger D, Kaleita T, et al
A comparison of neurocognitive functioning in children previously randomized to dexamethasone or prednisone in the treatment of childhood acute lymphoblastic leukemia.
Blood. 2009.
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DI VAL CERVO PR , Tucci P, Majid A, Lena MA, et al
p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia.
Blood. 2009;113:6498-9.
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MULLIGAN CS , Thomas ME, Mulligan SP
Lymphocytes, B lymphocytes, and clonal CLL cells: observations on the impact of the new diagnostic criteria in the 2008 Guidelines for Chronic Lymphocytic Leukemia (CLL).
Blood. 2009;113:6496-7.
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HANSON CA , Kurtin PJ, Dogan A
The proposed diagnostic criteria change for chronic lymphocytic leukemia: unintended consequences?
Blood. 2009;113:6495-6.
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SHIOTSU Y , Kiyoi H, Ishikawa Y, Tanizaki R, et al
KW-2449, a novel multi-kinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation.
Blood. 2009.
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ALONSO R , Lopez-Guerra M, Upshaw R, Bantia S, et al
Forodesine has high anti-tumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis via induction of p73 and BIM.
Blood. 2009.
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STONE RM
How I treat patients with myelodysplastic syndromes.
Blood. 2009;113:6296-303.
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JANKOWSKA AM , Szpurka H, Tiu RV, Makishima H, et al
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms.
Blood. 2009;113:6403-10.
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ZOU Z , Schmaier AA, Cheng L, Mericko P, et al
Negative regulation of activated alpha-2 integrins during thrombopoiesis.
Blood. 2009;113:6428-39.
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STANULLA M , Schaeffeler E, Moricke A, Coulthard SA, et al
Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Munster protocols.
Blood. 2009.
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VERMA D , Kantarjian HM, Jones D, Luthra R, et al
Chronic myeloid leukemia (CML) with P190BCR-ABL - analysis of characteristics, outcomes and prognostic significance.
Blood. 2009.
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BALGOBIND BV , Raimondi SC, Harbott J, Zimmermann M, et al
Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.
Blood. 2009.
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DE BOER NK , van Asseldonk DP, van Bodegraven AA
On the malignant potential of thiopurine therapy.
Blood. 2009;113:6258.
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LIEDTKE M , Cleary ML
Therapeutic targeting of MLL.
Blood. 2009;113:6061-8.
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CULLION K , Draheim KM, Hermance N, Tammam J, et al
Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
Blood. 2009;113:6172-81.
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NERVI B , Ramirez P, Rettig MP, Uy GL, et al
Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.
Blood. 2009;113:6206-14.
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ANSARI M , Sauty G, Labuda M, Gagne V, et al
Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia.
Blood. 2009.
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STEELE AJ , Prentice AG, Hoffbrand AV, Yogashangary BC, et al
2-phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells.
Blood. 2009.
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LANDRY JR , Bonadies N, Kinston S, Knezevic K, et al
Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors.
Blood. 2009;113:5783-92.
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QUIROGA MP , Balakrishnan K, Kurtova AV, Sivina M, et al
B cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel Syk inhibitor, R406.
Blood. 2009.
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May 2009

HORMAN SR , Velu CS, Chaubey A, Bourdeau T, et al
Gfi1 integrates progenitor versus granulocytic transcriptional programming.
Blood. 2009;113:5466-75.
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GHOSH AK , Shanafelt TD, Cimmino A, Taccioli C, et al
Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells.
Blood. 2009;113:5568-74.
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HAROUSSEAU JL , Martinelli G, Jedrzejczak WW, Brandwein JM, et al
A randomized phase 3 study of tipifarnib compared to best supportive care, including hydroxyurea, in the treatment of newly diagnosed acute myeloid leukemia (AML) in patients 70 years or older.
Blood. 2009.
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NACHMAN J
Apples and oranges: mixed lineage acute leukemia.
Blood. 2009;113:5036.
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SAMPATH D , Calin GA
miRs: fine-tuning prognosis in CLL.
Blood. 2009;113:5035-6.
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SCHNEIDER F , Hoster E, Unterhalt M, Schneider S, et al
NPM1 but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high-risk myelodysplastic syndrome (MDS).
Blood. 2009;113:5250-3.
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WRAY J , Williamson EA, Sheema S, Lee SH, et al
Metnase mediates chromosome decatenation in acute leukemia cells.
Blood. 2009.
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TAMBURINI J , Green AS, Bardet V, Chapuis N, et al
Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.
Blood. 2009.
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RENNER AG , Dos Santos C, Recher C, Bailly C, et al
Polo-like kinase 1 is over-expressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells.
Blood. 2009.
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GUTIERREZ A , Sanda T, Grebliunaite R, Carracedo A, et al
High frequency of PTEN, PI3K and AKT abnormalities in T cell acute lymphoblastic leukemia.
Blood. 2009.
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FRIGERI F , Arcamone M, Luciano L, Di Francia R, et al
Systemic dasatinib fails to prevent development of central nervous system progression in a patient with BCR-ABL unmutated Philadelphia chromosome-positive leukemia.
Blood. 2009;113:5028-9.
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GERTNER-DARDENNE J , Bonnafous C, Bezombes C, Capietto AH, et al
Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies.
Blood. 2009;113:4875-84.
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PEREZ-CAMPO FM , Borrow J, Kouskoff V, Lacaud G, et al
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors.
Blood. 2009;113:4866-74.
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BACCARANI M , Rosti G, Castagnetti F, Haznedaroglu I, et al
Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: a European LeukemiaNet Study.
Blood. 2009;113:4497-504.
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MUMPRECHT S , Claus C, Schurch C, Pavelic V, et al
Defective homing and impaired induction of cytotoxic T cells by BCR/ABL-expressing dendritic cells.
Blood. 2009;113:4681-9.
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FIELDING AK , Rowe JM, Richards SM, Buck G, et al
Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL
Blood. 2009;113:4489-96.
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KOENIGSMANN J , Rudolph C, Sander S, Kershaw O, et al
Nf1 haploinsufficiency and Icsbp deficiency synergize in the development of leukemias.
Blood. 2009;113:4690-701.
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ZHANG J , Jima DD, Jacobs C, Fischer R, et al
Patterns of microRNA expression characterize stages of human B-cell differentiation.
Blood. 2009;113:4586-94.
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MUMPRECHT S , Schurch C, Schwaller J, Solenthaler M, et al
PD-1 signaling on chronic myeloid leukemia-specific T cells results in T cell exhaustion and disease progression.
Blood. 2009.
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ZHANG L , Gajewski TF, Kline J
PD-1/PD-L1 interactions inhibit anti-tumor immune responses in a murine acute myeloid leukemia model.
Blood. 2009.
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QUINTAS-CARDAMA A , Han X, Kantarjian H, Cortes J, et al
Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia.
Blood. 2009.
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TAM CS , Shanafelt TD, Wierda WG, Abruzzo LV, et al
De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the MD Anderson and Mayo Clinic experience.
Blood. 2009.
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FUKUDA S , Singh P, Moh A, Abe M, et al
Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal-tandem-duplication of Flt3.
Blood. 2009.
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KCHOUR G , Tarhini M, Kooshyar MM, El Hajj H, et al
Phase II study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic ATL.
Blood. 2009.
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April 2009

HEIDENREICH O , Vormoor J
Malignant stem cells in childhood ALL: the debate continues!
Blood. 2009;113:4476-7.
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SECCHIERO P , Melloni E, di Iasio MG, Tiribelli M, et al
Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism.
Blood. 2009;113:4300-8.
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BASSAN R , Spinelli O, Oldani E, Intermesoli T, et al
Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL).
Blood. 2009;113:4153-62.
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YAN P , Fu J, Qu Z, Li S, et al
PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation.
Blood. 2009;113:4370-80.
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GORDON WR , Roy M, Vardar-Ulu D, Garfinkel M, et al
Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL.
Blood. 2009;113:4381-90.
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LANE SW , Scadden DT, Gilliland DG
The leukemic stem cell niche - current concepts and therapeutic opportunities.
Blood. 2009.
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SANTAMARIA CM , Chillon MC, Garcia-Sanz R, Perez C, et al
Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia (CN-AML).
Blood. 2009.
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METZELDER S , Wang Y, Wollmer E, Wanzel M, et al
Compassionate-use of sorafenib in Flt3-ITD positive acute myeloid leukemia: sustained regression prior and post allogenic stem cell transplantation.
Blood. 2009.
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MARNEROS AG , Grossman ME, Silvers DN, Husain S, et al
Pralatrexate-induced tumor cell apoptosis in the epidermis of a patient with HTLV-1 adult T-cell lymphoma/leukemia (ATLL) causing skin erosions.
Blood. 2009.
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ZHOU J , Bi C, Janakakumara JV, Liu SC, et al
Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML.
Blood. 2009;113:4052-62.
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PISE-MASISON CA , Radonovich M, Dohoney K, Morris JC, et al
Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability.
Blood. 2009;113:4016-26.
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PRATZ KW , Cortes J, Roboz GJ, Rao N, et al
A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response.
Blood. 2009;113:3938-46.
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DEL GIUDICE I , Chiaretti S, Tavolaro S, De Propris MS, et al
Spontaneous regression of chronic lymphocytic leukemia: clinical and biologic features of 9 cases.
Blood. 2009.
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YU J , Venstrom JM, Liu XR, Pring J, et al
Breaking tolerance to self, circulating natural killer cells expressing inhibitory KIR for non-self HLA exhibit effector function after T cell-depleted allogeneic hematopoietic cell transplantation.
Blood. 2009;113:3875-84.
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TREON SP , Branagan AR, Ioakimidis L, Soumerai JD, et al
Long-term outcomes to fludarabine and rituximab in Waldenstrom macroglobulinemia.
Blood. 2009;113:3673-8.
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WELDON JE , Xiang L, Chertov O, Margulies I, et al
A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.
Blood. 2009;113:3792-800.
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QUINTAS-CARDAMA A , Kantarjian H, Jones D, Shan J, et al
Delayed achievement of cytogenetic and molecular response is associated with increased risk of progression among patients with chronic myelogenous leukemia in early chronic phase receiving high-dose or standard-dose imatinib therapy.
Blood. 2009.
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KANTARJIAN H , Cortes J, Kim DW, Dorlhiac-Llacer P, et al
Phase III study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-month median follow-up.
Blood. 2009.
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WOLL PS , Grzywacz B, Tian X, Marcus RK, et al
Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo anti-tumor activity.
Blood. 2009.
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SCHMIDT-ARRAS D , Bohmer SA, Koch S, Muller JP, et al
Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality.
Blood. 2009;113:3568-76.
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PARK S , Chen W, Cierpicki T, Tonelli M, et al
Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.
Blood. 2009;113:3558-67.
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PREUDHOMME C , Renneville A, Bourdon V, Philippe N, et al
High frequency of RUNX1 bi-allelic alteration in acute myeloid leukemia (AML) secondary to familial platelet disorder (FPD).
Blood. 2009.
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VARDIMAN JW , Thiele J, Arber DA, Brunning RD, et al
The 2008 revision of the WHO classification of myeloid neoplasms and acute leukemia: rationale and important changes.
Blood. 2009.
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NOENS L , van Lierde MA, De Bock R, Verhoef G, et al
Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study.
Blood. 2009.
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WILSON NK , Miranda-Saavedra D, Kinston S, Bonadies N, et al
The transcriptional programme controlled by the stem cell leukaemia gene Scl/Tal1 during early embryonic haematopoietic development.
Blood. 2009.
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POPOVIC R , Riesbeck LE, Velu CS, Chaubey A, et al
Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization.
Blood. 2009;113:3314-22.
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March 2009

TER BRUGGE PJ , Ta VB, de Bruijn MJ, Keijzers G, et al
A mouse model for chronic lymphocytic leukemia based on expression of the SV40 large T antigen.
Blood. 2009.
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YU J , Ershler M, Yu L, Wei M, et al
TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia.
Blood. 2009.
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CHRISTOPEIT M , Schutte V, Theurich S, Weber T, et al
Rituximab reduces the incidence of acute graft-versus-host disease.
Blood. 2009;113:3130-1.
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GOBBI G , Mirandola P, Carubbi C, Micheloni C, et al
Phorbol ester-induced PKCepsilon down-modulation sensitizes AML cells to TRAIL-induced apoptosis and cell differentiation.
Blood. 2009;113:3080-7.
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NIEDERMEIER M , Hennessy BT, Knight ZA, Henneberg M, et al
Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach.
Blood. 2009.
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FURLAN I , Batz C, Flotho C, Mohr B, et al
Intriguing response to azacitidine in a patient with juvenile myelomonocytic leukemia and monosomy 7.
Blood. 2009;113:2867-8.
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HOLLER C , Pinon JD, Denk U, Heyder C, et al
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Blood. 2009;113:2791-4.
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MALINGE S , Izraeli S, Crispino JD
Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome.
Blood. 2009;113:2619-28.
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CHENG EC , Luo Q, Bruscia EM, Renda MJ, et al
Role for MKL1 in megakaryocytic maturation.
Blood. 2009;113:2826-34.
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KAWASE T , Matsuo K, Kashiwase K, Inoko H, et al
HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism.
Blood. 2009;113:2851-8.
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KNIGHT JA , Skol AD, Shinde A, Hastings D, et al
A genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility.
Blood. 2009.
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RENNEVILLE A , Boissel N, Gachard N, Naguib D, et al
The favorable impact of CEBPA mutations in patients with acute myeloid leukemia (AML) is only observed in the absence of associated cytogenetic abnormalities and FLT3 internal duplication (FLT3-ITD).
Blood. 2009.
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FAVA C , Kantarjian HM, Jabbour E, O'Brien S, et al
Failure to achieve a complete hematologic response at the time of achievement of a major cytogenetic response with second generation tyrosine kinase inhibitors is associated with a poor prognosis among patients with chronic myeloid leukemia in accelerate
Blood. 2009.
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FABER J , Krivtsov AV, Stubbs MC, Wright R, et al
HOXA9 is required for survival in human MLL-rearranged acute leukemias.
Blood. 2009;113:2375-85.
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Retraction. Roman-Gomez J, Jiminez-Velasco A, Castillejo JA, Agirre X, Barrios M, Navarro G, Molina FJ, Calasanz MJ, Prosper F, Heiniger A, Torres A. Promoter hypermethylation of cancer-related genes: a strong independent prognostic factor in acute lymph
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NORDE WJ , Overes IM, Maas F, Fredrix H, et al
Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1-reactive cytotoxic T cells.
Blood. 2009;113:2312-23.
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NORDIGARDEN A , Kraft M, Eliasson P, Labi V, et al
BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3.
Blood. 2009;113:2302-11.
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February 2009

BELLON M , Lepelletier Y, Hermine O, Nicot C, et al
Deregulation of micro-RNA involved in hematopoiesis and the immune response in HTLV-I adult T-cell leukemia.
Blood. 2009.
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LI Z , Beutel G, Rhein M, Meyer J, et al
High-affinity neurotrophin receptors and ligands promote leukemogenesis.
Blood. 2009;113:2028-37.
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MIYAZAKI K , Yamasaki N, Oda H, Kuwata T, et al
Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia.
Blood. 2009.
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CHEN R , Wierda WG, Chubb S, Hawtin RE, et al
Mechanism of action of SNS-032, a novel cyclin dependent kinase inhibitor, in chronic lymphocytic leukemia.
Blood. 2009.
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KANTARJIAN HM , O'Brien S
Insurance policies in the United States may explain part of the outcome differences of adolescents and young adults with acute lymphoblastic leukemia treated on adult versus pediatric regimens.
Blood. 2009;113:1861.
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TERRIOU L , Ben Abdelali R, Roumier C, Lhermitte L, et al
C/EBPA methylation is common in T-ALL but not in M0 AML.
Blood. 2009;113:1864-6.
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MAILLARD I , Chen YX, Friedman A, Yang Y, et al
Menin regulates the function of hematopoietic stem cells and lymphoid progenitors.
Blood. 2009;113:1661-9.
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AKAGI T , Shih LY, Kato M, Kawamata N, et al
Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations.
Blood. 2009;113:1741-8.
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FONSECA C , Soiffer R, Ho V, Vanneman M, et al
Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction.
Blood. 2009;113:1681-8.
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JOSHI I , Minter LM, Telfer J, Demarest RM, et al
Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases.
Blood. 2009;113:1689-98.
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ARMSTRONG F , de la Grange PB, Gerby B, Rouyez MC, et al
NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity.
Blood. 2009;113:1730-40.
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SCHMIEGELOW K , Al-Modhwahi I, Andersen MK, Behrendtz M, et al
Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia - results from the NOPHO ALL-92 study.
Blood. 2009.
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RIEDT T , Ebinger M, Salih HR, Tomiuk J, et al
Aberrant expression of the homeobox gene CDX2 in pediatric acute lymphoblastic leukemia.
Blood. 2009.
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GAIDZIK VI , Schlenk RF, Moschny S, Becker A, et al
Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia (AML): A study of the German-Austrian AML Study Group (AMLSG).
Blood. 2009.
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NOWAK D , Stewart D, Koeffler HP
Differentiation therapy of leukemia - three decades of development.
Blood. 2009.
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HEDDLE NM , Cook RJ, Tinmouth A, Kouroukis CT, et al
A randomized controlled trial comparing standard- and low-dose strategies for transfusion of platelets (SToP) to patients with thrombocytopenia.
Blood. 2009;113:1564-73.
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NAKAYAMA J , Yamamoto M, Hayashi K, Satoh H, et al
BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3.
Blood. 2009;113:1483-92.
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BASHEY A , Medina B, Corringham S, Pasek M, et al
CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation.
Blood. 2009;113:1581-8.
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RAUCH D , Gross S, Harding J, Niewiesk S, et al
Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors.
Blood. 2009;113:1493-500.
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CASTAGNETTI F , Palandri F, Amabile M, Testoni N, et al
Results of high-dose imatinib mesylate in intermediate SOKAL risk chronic myeloid leukemia patients in early chronic phase: A phase II trial of the GIMEMA CML WP.
Blood. 2009.
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GARZON R , Liu S, Fabbri M, Liu Z, et al
MicroRNA -29b induces global DNA hypomethylation and tumor suppressor gene re-expression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.
Blood. 2009.
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JIANG Y , Dunbar A, Gondek LP, Mohan S, et al
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.
Blood. 2009;113:1315-25.
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CRAZZOLARA R , Cisterne A, Thien M, Hewson J, et al
Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia.
Blood. 2009.
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LUCAS DM , Edwards RB, Lozanski G, West DA, et al
The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo.
Blood. 2009.
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January 2009

MILLER CP , Rudra S, Keating MJ, Wierda WG, et al
Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells.
Blood. 2009.
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GHOSH A , Koestner W, Hapke M, Schlaphoff V, et al
Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft versus leukemia effects across MHC barriers in full chimeras.
Blood. 2009.
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GUINN B , Greiner J, Schmitt M, Mills KI, et al
Elevated expression of the leukemia-associated antigen SSX2IP predicts survival in acute myeloid leukemia patients who lack detectable cytogenetic rearrangements.
Blood. 2009;113:1203-4.
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MESA RA , Hanson CA, Ketterling RP, Schwager S, et al
Trisomy 13: prevalence and clinicopathologic correlates of another potentially lenalidomide-sensitive cytogenetic abnormality.
Blood. 2009;113:1200-1.
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YIN B , Delwel R, Valk PJ, Wallace MR, et al
A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
Blood. 2009;113:1075-85.
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KUO YH , Zaidi SK, Gornostaeva S, Komori T, et al
Runx2 induces acute myeloid leukemia in cooperation with Cbf{beta}-SMMHC in mice.
Blood. 2009.
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WU QL , Zierold C, Ranheim EA
Dysregulation of frizzled 6 is a critical component of B cell leukemogenesis in a mouse model of chronic lymphocytic leukemia.
Blood. 2009.
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BACHANOVA V , Verneris MR, Defor T, Brunstein CG, et al
Prolonged survival in adults with acute lymphoblastic leukemia (ALL) following reduced intensity conditioning with cord blood or sibling donor transplantation.
Blood. 2009.
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HOLLINK IH , van den Heuvel-Eibrink MM, Zimmermann M, Balgobind BV, et al
Clinical relevance of Wilms' tumor 1 gene mutations in childhood acute myeloid leukemia.
Blood. 2009.
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WOUTERS BJ , Lowenberg B, Erpelinck-Verschueren CA, van Putten WL, et al
Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome.
Blood. 2009.
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NARDI V , Naveiras O, Azam M, Daley GQ, et al
ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines.
Blood. 2009.
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FIGUEROA ME , Wouters BJ, Skrabanek L, Glass J, et al
Genome wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features.
Blood. 2009.
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YAN M , Ahn EY, Hiebert SW, Zhang DE, et al
RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis.
Blood. 2009;113:883-6.
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OKAWA Y , Hideshima T, Steed P, Vallet S, et al
SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK.
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LI N , Chen Y, He W, Yi T, et al
Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic cell and donor T-cell migration in recipients conditioned with TBI.
Blood. 2009;113:953-62.
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ROSATI E , Sabatini R, Rampino G, Tabilio A, et al
Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells.
Blood. 2009;113:856-65.
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COX CV , Diamanti P, Evely RS, Kearns PR, et al
Expression of CD133 on leukemia initiating cells in childhood ALL.
Blood. 2009.
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GERMESHAUSEN M , Welte K, Ballmaier M
In vivo expansion of cells expressing acquired CSF3R mutations in patients with severe congenital neutropenia.
Blood. 2009;113:668-70.
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KEARNEY L , Gonzalez De Castro D, Yeung J, Procter J, et al
Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.
Blood. 2009;113:646-8.
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ZHAO H , Kalota A, Jin S, Gewirtz AM, et al
The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells.
Blood. 2009;113:505-16.
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BREITENBUECHER F , Markova B, Kasper S, Carius B, et al
A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in acute myeloid leukemia.
Blood. 2009.
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STAMATOPOULOS B , Meuleman N, Haibe-Kains B, Saussoy P, et al
MicroRNA-29c and microRNA-223 downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification.
Blood. 2009.
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BURMEISTER T , Meyer C, Schwartz S, Hofmann J, et al
The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia - results from the GMALL study group.
Blood. 2009.
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KIM DH , Xu W, Ma C, Liu X, et al
Genetic variants in the candidate genes of the apoptosis pathway and susceptibility to chronic myeloid leukemia.
Blood. 2009.
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PITINI V , Arrigo C, Altavilla G
Dasatinib induces a response in chronic lymphocytic leukemia.
Blood. 2009;113:498.
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BRAESS J , Spiekermann K, Staib P, Gruneisen A, et al
Dose-dense induction with sequential-high-dose cytarabine and mitoxantone (S-HAM) and pegfilgrastim results in a high efficacy and a short duration of critical neutropenia in de-novo acute myeloid leukemia - a pilot study of the AML-CG.
Blood. 2009.
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STARK M , Wichman C, Avivi I, Assaraf YG, et al
Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia.
Blood. 2009.
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WEINBERG OK , Seetharam M, Ren L, Seo K, et al
Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system.
Blood. 2009.
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RUBNITZ JE , Onciu M, Pounds S, Shurtleff S, et al
Acute mixed lineage leukemia in children: The experience of St. Jude Children's Research Hospital.
Blood. 2009.
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KUWATSUKA Y , Miyamura K, Suzuki R, Kasai M, et al
Hematopoietic stem cell transplantation for core binding factor acute myeloid leukemia: t(8;21) and inv(16) represent different clinical outcomes.
Blood. 2009.
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MARSTON E , Weston V, Jesson J, Maina E, et al
Stratification of pediatric ALL by in vitro cellular responses to DNA double-strand breaks provides insight into the molecular mechanisms underlying clinical response.
Blood. 2009;113:117-26.
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KORNBLAU SM , Tibes R, Qiu YH, Chen W, et al
Functional proteomic profiling of AML predicts response and survival.
Blood. 2009;113:154-64.
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SULONG S , Moorman AV, Irving JA, Strefford JC, et al
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups.
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BALAKRISHNAN K , Burger JA, Wierda WG, Gandhi V, et al
AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance.
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December 2008

KUMAR AR , Li Q, Hudson WA, Chen W, et al
A role for MEIS1 in MLL-fusion gene leukemia.
Blood. 2008.
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KARP JE , Flatten K, Feldman EJ, Greer JM, et al
Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: A preclinical and phase I trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide.
Blood. 2008.
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ASNAFI V , Buzyn A, Le Noir S, Baleydier F, et al
NOTCH1/FBXW7 mutation identifies a large subgroup with favourable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a GRAALL study.
Blood. 2008.
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YANG H , Kadia T, Xiao L, Bueso-Ramos CE, et al
Residual DNA methylation at remission is prognostic in adult Philadelphia chromosome negative acute lymphocytic leukemia.
Blood. 2008.
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ATSUTA Y , Suzuki R, Nagamura-Inoue T, Taniguchi S, et al
Disease-specific analyses of unrelated cord blood transplant compared with unrelated bone marrow transplant in adult patients with acute leukemia.
Blood. 2008.
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SAMPATH D , Calin GA, Puduvalli VK, Gopisetty G, et al
Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase, Itch for degradation.
Blood. 2008.
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KU GH , White RH, Chew HK, Harvey DJ, et al
Venous thromboembolism in patients with acute leukemia: incidence, risk factors, and effect on survival.
Blood. 2008.
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TYNER JW , Erickson H, Deininger MW, Willis SG, et al
High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients.
Blood. 2008.
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CHEN X , Bai F, Sokol L, Zhou J, et al
A critical role for DAP10 and DAP12 in CD8+ T cell-mediated tissue damage in large granular lymphocyte leukemia.
Blood. 2008.
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DRUKER BJ
Translation of the Philadelphia chromosome into therapy for CML.
Blood. 2008;112:4808-17.
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WEISBERG E , Roesel J, Bold G, Furet P, et al
Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells.
Blood. 2008;112:5161-70.
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JABBOUR E , Kantarjian HM, Jones D, Reddy N, et al
Characteristics and outcome of chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation after therapy with tyrosine kinase inhibitors.
Blood. 2008;112:4839-42.
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JONES D , Luthra R, Cortes J, Thomas D, et al
BCR-ABL fusion transcript types and levels and their interaction with secondary genetic changes in determining the phenotype of Philadelphia chromosome-positive leukemias.
Blood. 2008;112:5190-2.
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HEUZE ML , Lamsoul I, Baldassarre M, Lad Y, et al
ASB2 targets filamins A and B to proteasomal degradation.
Blood. 2008;112:5130-40.
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HALLAERT DY , Jaspers A, van Noesel CJ, van Oers MH, et al
c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches.
Blood. 2008;112:5141-9.
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BURGER JA , Quiroga MP, Hartmann E, Burkle A, et al
High-level expression of the T cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell co-cultures and after BCR stimulation.
Blood. 2008.
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FRENCH D , Yang W, Cheng C, Raimondi SC, et al
Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia.
Blood. 2008.
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ZHANG J , Wang J, Liu Y, Sidik H, et al
Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.
Blood. 2008.
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LEVY DS , Kahana JA, Kumar R
AKT inhibitor, GSK690693, induces growth inhibition and apoptosis in acute lymphoblastic leukemia cell lines.
Blood. 2008.
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ZHAO T , Yasunaga JI, Satou Y, Nakao M, et al
Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-{kappa}B.
Blood. 2008.
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JABBOUR E , Kantarjian HM, Jones D, Shan J, et al
Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia post cytogenetic failure on standard-dose imatinib therapy.
Blood. 2008.
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RINGDEN O , Pavletic SZ, Anasetti C, Barrett AJ, et al
The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation.
Blood. 2008.
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LIN KI , Tam CS, Keating MJ, Wierda WG, et al
Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens.
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KOLB HJ
Graft-versus-leukemia effects of transplantation and donor lymphocytes.
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RODRIGUEZ-CABALLERO A , Garcia-Montero AC, Barcena P, Almeida J, et al
Expanded cells in monoclonal TCR-alphabeta+/CD4+/NKa+/CD8-/+dim T-LGL lymphocytosis recognize hCMV antigens.
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OWEN CJ , Toze CL, Koochin A, Forrest DL, et al
Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy.
Blood. 2008;112:4639-45.
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MARIN D , Milojkovic D, Olavarria E, Khorashad JS, et al
European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor.
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TUNSTALL-PEDOE O , Roy A, Karadimitris A, de la Fuente J, et al
Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations.
Blood. 2008;112:4507-11.
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WU X , Darce JR, Chang SK, Nowakowski GS, et al
Alternative splicing regulates activation-induced cytidine deaminase (AID): implications for suppression of AID mutagenic activity in normal and malignant B cells.
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ZEBEDIN E , Simma O, Schuster C, Putz EM, et al
Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance.
Blood. 2008;112:4655-64.
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November 2008

FAKLER M , Loder S, Vogler M, Schneider K, et al
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance.
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HORTON SJ , Walf-Vorderwulbecke V, Chatters SJ, Sebire NJ, et al
Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.
Blood. 2008.
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DE JONGE R , Tissing WJ, Hooijberg JH, Jansen G, et al
Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia.
Blood. 2008.
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DEROLF AR , Kristinsson SY, Andersson TM, Landgren O, et al
Improved patient survival for acute myeloid leukemia: A population-based study of 9,729 patients diagnosed in Sweden 1973-2005.
Blood. 2008.
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SHANAFELT TD , Kay NE, Jenkins G, Call TG, et al
B-cell count and survival: Differentiating chronic lymphocytic leukemia (CLL) from monoclonal B-cell lymphocytosis (MBL) based on clinical outcome.
Blood. 2008.
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HUGHES TP , Branford S, White DL, Reynolds J, et al
Impact of early dose intensity on cytogenetic and molecular responses in chronic- phase CML patients receiving 600 mg/day of imatinib as initial therapy.
Blood. 2008;112:3965-73.
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WANG PY , Young F, Chen CY, Stevens BM, et al
The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene.
Blood. 2008;112:4184-92.
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PALLASCH CP , Schulz A, Kutsch N, Schwamb J, et al
Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease.
Blood. 2008;112:4213-9.
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VOGLER M , Butterworth M, Majid A, Walewska RJ, et al
Concurrent upregulation of BCL-XL and BCL2A1 induces ~1000-fold resistance to ABT-737 in chronic lymphocytic leukemia.
Blood. 2008.
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AWAN FT , Kay NE, Davis ME, Wu W, et al
Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab.
Blood. 2008.
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JULIUSSON G , Antunovic P, Derolf A, Lehmann S, et al
Age and acute myeloid leukemia. Real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry.
Blood. 2008.
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MELENHORST JJ , Scheinberg P, Chattopadhyay PK, Gostick E, et al
High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow.
Blood. 2008.
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REZVANI K , Yong AS, Tawab A, Jafarpour B, et al
Ex-vivo characterization of polyclonal memory CD8+ T-cell responses to PRAME-specific peptides in patients with acute lymphoblastic leukemia and acute and chronic myeloid leukemia.
Blood. 2008.
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CORNELISSEN JJ , Holt BV, Verhoef GE, Veer MB, et al
Myeloablative allogeneic versus autologous stem cell transplantation in adult patients with acute lymphoblastic leukemia in first remission: a prospective sibling donor versus no-donor comparison.
Blood. 2008.
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SHIH TT , Hou HA, Liu CY, Chen BB, et al
Bone marrow angiogenesis MR imaging in patients with acute myeloid leukemia: Peak enhancement ratio is an independent predictor for overall survival.
Blood. 2008.
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PHELPS MA , Lin TS, Johnson AJ, Hurh E, et al
Clinical response and pharmacokinetics from a phase I study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia.
Blood. 2008.
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WEE HJ , Voon DC, Bae SC, Ito Y, et al
PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis.
Blood. 2008;112:3777-87.
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STEELE AJ , Prentice AG, Hoffbrand AV, Yogashangary BC, et al
p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism.
Blood. 2008;112:3827-34.
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LIU FT , Agrawal SG, Movasaghi Z, Wyatt PB, et al
Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib.
Blood. 2008;112:3835-46.
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KAWAHARA M , Hori T, Chonabayashi K, Oka T, et al
Kpm/Lats2 is linked to chemosensitivity of leukemic cells through the stabilization of p73.
Blood. 2008;112:3856-66.
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October 2008

HULLEMAN E , Kazemier KM, Holleman A, Vanderweele DJ, et al
Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells.
Blood. 2008.
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PULTE D , Gondos A, Brenner H
Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century.
Blood. 2008.
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FIEGL M , Samudio I, Clise-Dwyer K, Burks JK, et al
CXCR4 expression and biological activity in acute myeloid leukemia are dependent on oxygen partial pressure.
Blood. 2008.
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ZENG Z , Shi YX, Samudio IJ, Wang RY, et al
Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.
Blood. 2008.
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KIM WI , Matise I, Diers MD, Largaespada DA, et al
RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.
Blood. 2008.
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HARIKUMAR KB , Kunnumakkara AB, Ahn KS, Anand P, et al
Modification of the cysteine residues in I{kappa}B {alpha} kinase and NF-{kappa}B (p65) by xanthohumol leads to suppression of NF-{kappa}B-regulated gene products and potentiation of apoptosis in leukemia cells.
Blood. 2008.
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MADAN V , Madan B, Brykczynska U, Zilbermann F, et al
Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog Mll5.
Blood. 2008.
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CHEN J , Zhang M, Ju W, Waldmann TA, et al
Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25.
Blood. 2008.
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HADZIDIMITRIOU A , Darzentas N, Murray F, Smilevska T, et al
Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia.
Blood. 2008.
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PENDE D , Marcenaro S, Falco M, Martini S, et al
Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and re-definition of inhibitory KIR specificity.
Blood. 2008.
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MONTESINOS P , Bergua JM, Vellenga E, Rayon C, et al
Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-transretinoic acid and anthracycline chemotherapy: characteristics, outcome and prognostic factors.
Blood. 2008.
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COOLEY S , Trachtenberg E, Bergemann TL, Saeteurn K, et al
Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.
Blood. 2008.
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ZENZ T , Mohr J, Eldering E, Kater AP, et al
MiR-34a as part of the chemotherapy resistance network in chronic lymphocytic leukemia.
Blood. 2008.
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SAUMET A , Vetter G, Bouttier M, Portales-Casamar E, et al
Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia.
Blood. 2008.
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O'BRIEN SM , Claxton DF, Crump M, Faderl S, et al
Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia.
Blood. 2008.
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BECKER PS , Kopecky KJ, Wilks AN, Chien S, et al
Very late antigen-4 (VLA-4) function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia.
Blood. 2008.
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GRUBOR V , Krasnitz A, Troge JE, Meth JL, et al
Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA).
Blood. 2008.
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YONG AS , Keyvanfar K, Hensel N, Eniafe R, et al
Primitive quiescent CD34+ cells in chronic myeloid leukemia are targeted by in vitro expanded natural killer cells, which are functionally enhanced by bortezomib.
Blood. 2008.
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ZENZ T , Krober A, Scherer K, Habe S, et al
Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up.
Blood. 2008;112:3322-9.
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BRANFORD S , Fletcher L, Cross NC, Muller MC, et al
Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials.
Blood. 2008;112:3330-8.
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GIANNOUDIS A , Davies A, Lucas CM, Harris RJ, et al
Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia.
Blood. 2008;112:3348-54.
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SUGIYAMA H
Expectation for DNA leukemia vaccines.
Blood. 2008;112:2602.
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KOJIMA K , Konopleva M, Tsao T, Nakakuma H, et al
Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia.
Blood. 2008;112:2886-95.
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PAOLUZZI L , Gonen M, Bhagat G, Furman RR, et al
The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies.
Blood. 2008;112:2906-16.
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CHAISE C , Buchan SL, Rice J, Marquet J, et al
DNA vaccination induces WT1-specific T-cell responses with potential clinical relevance.
Blood. 2008;112:2956-64.
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September 2008

QUINTAS-CARDAMA A , Cortes J
Molecular biology of BCR-ABL1-positive chronic myeloid leukemia.
Blood. 2008.
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SEKERES MA , Elson P, Kalaycio ME, Advani AS, et al
Time from diagnosis to treatment initiation predicts survival in younger, but not older, acute myeloid leukemia patients.
Blood. 2008.
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FEHNIGER TA , Byrd JC, Marcucci G, Abboud CN, et al
Single agent lenalidomide induces complete remission of acute myeloid leukemia in patients with isolated trisomy 13.
Blood. 2008.
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OCHI T , Fujiwara H, Suemori K, Azuma T, et al
Aurora-A kinase: A novel target of cellular immunotherapy for leukemia.
Blood. 2008.
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ZHANG Y , Wong J, Klinger M, Tran MT, et al
Mll5 contributes to hematopoietic stem cell fitness and homeostasis.
Blood. 2008.
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CHU CC , Catera R, Hatzi K, Yan XJ, et al
Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize non-muscle myosin heavy chain IIA.
Blood. 2008.
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SANZ MA , Grimwade D, Tallman MS, Lowenberg B, et al
Guidelines on the management of acute promyelocytic leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet.
Blood. 2008.
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PIETERS R , Appel I, Kuehnel HJ, Tetzlaff-Fohr I, et al
Pharmacokinetics, pharmacodynamics, efficacy and safety of a new recombinant asparaginase preparation in children with previously untreated acute lymphoblastic leukemia- a randomized phase II clinical trial.
Blood. 2008.
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MORTON LM , Wang SS, Cozen W, Linet MS, et al
Etiologic heterogeneity among non-Hodgkin lymphoma subtypes.
Blood. 2008.
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DAVE UP
Leukemia takes center (late) stage.
Blood. 2008;112:2175-6.
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DORRANCE AM , Liu S, Chong A, Pulley B, et al
The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele.
Blood. 2008;112:2508-11.
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CHIRON D , Bekeredjian-Ding I, Pellat-Deceunynck C, Bataille R, et al
Toll-like receptors: lessons to learn from normal and malignant human B cells.
Blood. 2008;112:2205-13.
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NEWRZELA S , Cornils K, Li Z, Baum C, et al
Resistance of mature T cells to oncogene transformation.
Blood. 2008;112:2278-86.
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LANDGREN O , Goldin LR, Kristinsson SY, Helgadottir EA, et al
Increased risks of polycythemia vera, essential thrombocythemia, and myelofibrosis among 24,577 first-degree relatives of 11,039 patients with myeloproliferative neoplasms in Sweden.
Blood. 2008;112:2199-204.
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EPLING-BURNETTE PK , Sokol L, Chen X, Bai F, et al
Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling.
Blood. 2008.
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FUKUMOTO R , Andresen V, Bialuk I, Cecchinato V, et al
In vivo genetic mutations define predominant functions of the human T-cell leukemia/lymphoma virus p12I protein.
Blood. 2008.
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DWORZAK MN , Schumich A, Printz D, Potschger U, et al
CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immuno-therapy.
Blood. 2008.
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CUTLER C , Stevenson K, Kim HT, Richardson P, et al
Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation.
Blood. 2008.
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LAPALOMBELLA R , Yu B, Triantafillou G, Liu Q, et al
Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells.
Blood. 2008.
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TRENTIN L , Frasson M, Donella-Deana A, Frezzato F, et al
Geldanamycin-induced Lyn dissociation from aberrant HSP90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia.
Blood. 2008.
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YANG JJ , Bhojwani D, Yang W, Cai X, et al
Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia.
Blood. 2008.
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KIPPS TJ
Genomic complexity in chronic lymphocytic leukemia.
Blood. 2008;112:1550.
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SEYFRIED I , Hofbauer S, Stoecher M, Greil R, et al
SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a.
Blood. 2008;112:2168.
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SMOLEJ L
Valganciclovir versus valaciclovir for prevention of alemtuzumab-induced cytomegalovirus reactivation: what are the implications for routine clinical practice?
Blood. 2008;112:2167.
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LEBIEN TW , Tedder TF
B lymphocytes: how they develop and function.
Blood. 2008;112:1570-80.
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TRACHOOTHAM D , Zhang H, Zhang W, Feng L, et al
Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism.
Blood. 2008;112:1912-22.
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TAM CS , Nussenzveig RM, Popat U, Bueso-Ramos CE, et al
The natural history and treatment outcome of blast phase BCR-ABL- myeloproliferative neoplasms.
Blood. 2008;112:1628-37.
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SLAPE C , Liu LY, Beachy S, Aplan PD, et al
Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Blood. 2008;112:2017-9.
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AGARWAL A , Bumm TG, Corbin AS, O'Hare T, et al
Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease.
Blood. 2008;112:1960-70.
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TAM WF , Gu TL, Chen J, Lee BH, et al
Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.
Blood. 2008;112:1981-92.
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SOLIERA AR , Lidonnici MR, Ferrari-Amorotti G, Prisco M, et al
Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPalpha in p210BCR/ABL-expressing cells.
Blood. 2008;112:1942-50.
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August 2008

MALINGE S , Ragu C, Della-Valle V, Pisani D, et al
Activating mutations in human acute megakaryoblastic leukemia.
Blood. 2008.
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METZELER KH , Hummel M, Bloomfield CD, Spiekermann K, et al
An 86 probe set gene expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
Blood. 2008.
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TROEGER A , Glouchkova L, Ackermann B, Escherich G, et al
High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95.
Blood. 2008;112:1028-34.
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MANIECKI MB , Hasle H, Friis-Hansen L, Lausen B, et al
Impaired CD163-mediated hemoglobin-scavenging and severe toxic symptoms in patients treated with gemtuzumab ozogamicin.
Blood. 2008;112:1510-4.
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AU WY , Tam S, Fong BM, Kwong YL, et al
Determinants of cerebrospinal fluid arsenic concentration in patients with acute promyelocytic leukemia on oral arsenic trioxide therapy.
Blood. 2008.
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THOMAS DA , O'Brien S, Jorgensen JL, Cortes J, et al
Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia.
Blood. 2008.
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WOUTERS BJ , Lowenberg B, Delwel R
A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects.
Blood. 2008.
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KRISTINSSON SY , Bjorkholm M, Goldin LR, McMaster ML, et al
Risk of lymphoproliferative disorders among first-degree relatives of lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia patients: A population-based study in Sweden.
Blood. 2008.
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WOOLFREY AE , Malhotra U, Harrington RD, McNevin J, et al
Generation of HIV-1 specific CD8+ cell responses following allogeneic hematopoietic cell transplant.
Blood. 2008.
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ARNOLD J , Zimmerman B, Li M, Lairmore MD, et al
Human T-cell Leukemia Virus Type-1 Antisense-encoded Gene, Hbz, Promotes T Lymphocyte Proliferation.
Blood. 2008.
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COHEN IJ
High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphatic leukemia.
Blood. 2008;112:910.
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Erythroid karyorrhexis in myelodysplasia: bone marrow aspirate.
Blood. 2008;112:479.
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BURMEISTER T , Schwartz S, Bartram CR, Gokbuget N, et al
Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group.
Blood. 2008;112:918-9.
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YANG J , Chai L, Gao C, Fowles TC, et al
SALL4 is a key regulator of survival and apoptosis in human leukemic cells.
Blood. 2008;112:805-13.
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SULIS ML , Williams O, Palomero T, Tosello V, et al
NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL.
Blood. 2008;112:733-40.
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July 2008

SANZ MA , Montesinos P, Vellenga E, Rayon C, et al
Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: long-term outcome of the LPA 99 multicenter study by the PETHEMA group.
Blood. 2008.
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LEE SJ , Kukreja M, Wang T, Giralt SA, et al
Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia.
Blood. 2008.
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STARCZYNOWSKI DT , Vercauteren S, Telenius A, Sung S, et al
High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival.
Blood. 2008.
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CHENG CK , Li L, Cheng SH, Lau KM, et al
Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia.
Blood. 2008.
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KINDLER T , Cornejo MG, Scholl C, Liu J, et al
K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to {gamma}-secretase inhibitors.
Blood. 2008.
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FISKUS W , Rao R, Fernandez P, Herger B, et al
Molecular and biologic characterization and drug-sensitivity of pan histone deacetylase inhibitor resistant acute myeloid leukemia cells.
Blood. 2008.
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IACOBUCCI I , Lonetti A, Messa F, Cilloni D, et al
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance.
Blood. 2008.
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HASAN SK , Mays AN, Ottone T, Ledda A, et al
Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis.
Blood. 2008.
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VAGO L , Forno B, Sormani MP, Crocchiolo R, et al
Temporal, quantitative and functional characteristics of single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT.
Blood. 2008.
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PROTO-SIQUEIRA R , Panepucci RA, Careta FP, Lee A, et al
SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL.
Blood. 2008;112:394-7.
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June 2008

ZHOU Y , Du W, Koretsky T, Bagby GC, et al
TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice.
Blood. 2008;.
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May 2008

STERN M , Ruggeri L, Mancusi A, Bernardo ME, et al
Survival after T-cell depleted haploidentical stem cell transplantation is improved using the mother as donor.
Blood. 2008;.
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KUMPERS P , Koenecke C, Hecker H, Hellpap J, et al
Angiopoietin-2 predicts disease-free survival after allogeneic stem-cell transplantation in patients with high-risk myeloid malignancies.
Blood. 2008;.
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