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Articles published in Antimicrob Agents Chemother

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Single Articles


    April 2024
  1. HARTUIS S, Ourliac-Garnier I, Robert E, Albassier M, et al
    Precise genome editing underlines the distinct contributions of mutations in ERG11, ERG3, MRR1, and TAC1 genes to antifungal resistance in Candida parapsilosis.
    Antimicrob Agents Chemother. 2024 Apr 16:e0002224. doi: 10.1128/aac.00022.
    PubMed     Abstract available


  2. KENGO A, Nabeemeeah F, Denti P, Sabet R, et al
    Assessing potential drug-drug interactions between clofazimine and other frequently used agents to treat drug-resistant tuberculosis.
    Antimicrob Agents Chemother. 2024 Apr 10:e0158323. doi: 10.1128/aac.01583.
    PubMed     Abstract available


  3. LOSSOUARN J, Beurrier E, Bouteau A, Moncaut E, et al
    The virtue of training: extending phage host spectra against vancomycin-resistant Enterococcus faecium strains using the Appelmans method.
    Antimicrob Agents Chemother. 2024 Apr 9:e0143923. doi: 10.1128/aac.01439.
    PubMed     Abstract available


  4. POONAWALA H, Zhang Y, Kuchibhotla S, Green AG, et al
    Transcriptomic responses to antibiotic exposure in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2024 Apr 8:e0118523. doi: 10.1128/aac.01185.
    PubMed     Abstract available


  5. WEI X, Gao J, Zhou D, Xu C, et al
    Murepavadin promotes the killing efficacies of aminoglycoside antibiotics against Pseudomonas aeruginosa by enhancing membrane potential.
    Antimicrob Agents Chemother. 2024;68:e0153923.
    PubMed     Abstract available


  6. ASLAM S, Roach D, Nikolich MP, Biswas B, et al
    Pseudomonas aeruginosa ventricular assist device infections: findings from ineffective phage therapies in five cases.
    Antimicrob Agents Chemother. 2024;68:e0172823.
    PubMed     Abstract available


  7. GSCHWIND R, Petitjean M, Fournier C, Lao J, et al
    Inter-phylum circulation of a beta-lactamase-encoding gene: a rare but observable event.
    Antimicrob Agents Chemother. 2024;68:e0145923.
    PubMed     Abstract available


  8. XUE J, Li W, Zhao Y, Wang L, et al
    Antibiotic-induced ROS-mediated Fur allosterism contributes to Helicobacter pylori resistance by inhibiting arsR activation of mutS and mutY.
    Antimicrob Agents Chemother. 2024;68:e0167923.
    PubMed     Abstract available


  9. RIBEIRO DOS SANTOS A, Gade L, Misas E, Litvintseva AP, et al
    Bimodal distribution of azole susceptibility in Sporothrix brasiliensis isolates in Brazil.
    Antimicrob Agents Chemother. 2024;68:e0162023.
    PubMed     Abstract available


  10. TAIT JR, Anderson D, Nation RL, Creek DJ, et al
    Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024;68:e0108123.
    PubMed     Abstract available


    March 2024
  11. LOCKE JB, Pillar CM, Castanheira M, Carvalhaes CG, et al
    Outcomes by Candida spp. in the ReSTORE Phase 3 trial of rezafungin versus caspofungin for candidemia and/or invasive candidiasis.
    Antimicrob Agents Chemother. 2024 Mar 25:e0158423. doi: 10.1128/aac.01584.
    PubMed     Abstract available


  12. SEGAWA T, Masuda K, Hisatsune J, Ishida-Kuroki K, et al
    Genomic analysis of inter-hospital transmission of vancomycin-resistant Enterococcus faecium sequence type 80 isolated during an outbreak in Hiroshima, Japan.
    Antimicrob Agents Chemother. 2024 Mar 20:e0171623. doi: 10.1128/aac.01716.
    PubMed     Abstract available


  13. SUN L, Zhuang H, Chen M, Chen Y, et al
    Vancomycin heteroresistance caused by unstable tandem amplifications of the vanM gene cluster on linear conjugative plasmids in a clinical Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Mar 20:e0115923. doi: 10.1128/aac.01159.
    PubMed     Abstract available


  14. LYONS MA, Obregon-Henao A, Ramey ME, Bauman AA, et al
    Use of multiple pharmacodynamic measures to deconstruct the Nix-TB regimen in a short-course murine model of tuberculosis.
    Antimicrob Agents Chemother. 2024 Mar 19:e0101023. doi: 10.1128/aac.01010.
    PubMed     Abstract available


  15. VILLELLAS C, Stevenaert F, Remmerie B, Andries K, et al
    Sub-MIC levels of bedaquiline and clofazimine can select Mycobacterium tuberculosis mutants with increased MIC.
    Antimicrob Agents Chemother. 2024 Mar 12:e0127523. doi: 10.1128/aac.01275.
    PubMed     Abstract available


  16. HILLIARD JJ, Jakielaszek C, Mannino F, Hossain M, et al
    Efficacy of therapeutically administered gepotidacin in a rabbit model of inhalational anthrax.
    Antimicrob Agents Chemother. 2024;68:e0149723.
    PubMed     Abstract available


  17. HOSODA K, Koyama N, Shigeno S, Nishimura T, et al
    Mavintramycin A is a promising antibiotic for treating Mycobacterium avium complex infectious disease.
    Antimicrob Agents Chemother. 2024;68:e0091723.
    PubMed     Abstract available


  18. ZHANG X, Wang Y, Li S, Xie F, et al
    Simulated drug disposition in critically ill patients to evaluate effective PK/PD targets for combating Pseudomonas aeruginosa resistance to meropenem.
    Antimicrob Agents Chemother. 2024;68:e0154123.
    PubMed     Abstract available


  19. ANDRE C, Van Camp AG, Ung L, Gilmore MS, et al
    Characterization of the resistome and predominant genetic lineages of Gram-positive bacteria causing keratitis.
    Antimicrob Agents Chemother. 2024;68:e0124723.
    PubMed     Abstract available


  20. DUREJA C, Rutherford JT, Pavel FB, Norseeda K, et al
    In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy.
    Antimicrob Agents Chemother. 2024;68:e0122223.
    PubMed     Abstract available


  21. SALILLAS S, Raaijmakers J, Aarnoutse RE, Svensson EM, et al
    Clofazimine as a substitute for rifampicin improves efficacy of Mycobacterium avium pulmonary disease treatment in the hollow-fiber model.
    Antimicrob Agents Chemother. 2024;68:e0115723.
    PubMed     Abstract available


  22. KOTTOM TJ, Carmona EM, Limper AH
    Characterization of the Pneumocystis jirovecii and Pneumocystis murina phosphoglucomutases (Pgm2s): a potential target for Pneumocystis therapy.
    Antimicrob Agents Chemother. 2024;68:e0075623.
    PubMed     Abstract available


  23. CARUSO L, Mellini M, Catalano Gonzaga O, Astegno A, et al
    Hydrogen sulfide production does not affect antibiotic resistance in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024 Mar 6:e0007524. doi: 10.1128/aac.00075.
    PubMed     Abstract available


    February 2024
  24. SARANGI J, Ido A, Ito M, Iinuma C, et al
    Clinical isolates of Streptococcus mitis/oralis-related species with reduced carbapenem susceptibility, harboring amino acid substitutions in penicillin-binding proteins in Japan.
    Antimicrob Agents Chemother. 2024 Feb 28:e0117923. doi: 10.1128/aac.01179.
    PubMed     Abstract available


  25. OLIVENCA F, Pires D, Silveiro C, Gama B, et al
    Ethambutol and meropenem/clavulanate synergy promotes enhanced extracellular and intracellular killing of Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2024 Feb 27:e0158623. doi: 10.1128/aac.01586.
    PubMed     Abstract available


  26. LI S-Y, Tyagi S, Soni H, Betoudji F, et al
    Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis.
    Antimicrob Agents Chemother. 2024 Feb 20:e0156223. doi: 10.1128/aac.01562.
    PubMed     Abstract available


  27. TRUONG-BOLDUC QC, Wang Y, Ferrer-Espada R, Reedy JL, et al
    Staphylococcus aureus AbcA transporter enhances persister formation under beta-lactam exposure.
    Antimicrob Agents Chemother. 2024 Feb 16:e0134023. doi: 10.1128/aac.01340.
    PubMed     Abstract available


  28. BASSERES E, Eubank TA, Begum K, Alam MJ, et al
    Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.
    Antimicrob Agents Chemother. 2024 Feb 16:e0162123. doi: 10.1128/aac.01621.
    PubMed     Abstract available


  29. ERSOY SC, Proctor RA, Rose WE, Abdelhady W, et al
    Sensitizing methicillin-resistant Staphylococcus aureus (MRSA) to cefuroxime: the synergic effect of bicarbonate and the wall teichoic acid inhibitor ticlopidine.
    Antimicrob Agents Chemother. 2024 Feb 13:e0162723. doi: 10.1128/aac.01627.
    PubMed     Abstract available


  30. ORTIZ DE LA ROSA JM, Martin-Gutierrez G, Casimiro-Soriguer CS, Gimeno-Gascon MA, et al
    C-terminal deletion of RelA protein is suggested as a possible cause of infective endocarditis recurrence with Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Feb 13:e0108323. doi: 10.1128/aac.01083.
    PubMed     Abstract available


  31. FLEMING D, Bozyel I, Ozdemir D, Otero JA, et al
    HOCl-producing electrochemical bandage for treating Pseudomonas aeruginosa-infected murine wounds.
    Antimicrob Agents Chemother. 2024;68:e0121623.
    PubMed     Abstract available


  32. ANTONELLI A, Coppi M, Bonaiuto C, Giovacchini N, et al
    Novel resistance ICEs carrying the bla(FIM-1) metallo-beta-lactamase gene from an ST235 Pseudomonas aeruginosa sublineage.
    Antimicrob Agents Chemother. 2024;68:e0120523.
    PubMed     Abstract available


  33. KOTTOM TJ, Carmona EM, Limper AH
    Targeting host tyrosine kinase receptor EphA2 signaling via small-molecule ALW-II-41-27 inhibits macrophage pro-inflammatory signaling responses to Pneumocystis carinii beta-glucans.
    Antimicrob Agents Chemother. 2024;68:e0081123.
    PubMed     Abstract available


  34. MCDONALD RA, Nagy SG, Chambers M, Broberg CA, et al
    Nitric oxide-releasing prodrug for the treatment of complex Mycobacterium abscessus infections.
    Antimicrob Agents Chemother. 2024;68:e0132723.
    PubMed     Abstract available


  35. PITOUT JDD, Peirano G, Matsumura Y, DeVinney R, et al
    Escherichia coli sequence type 410 with carbapenemases: a paradigm shift within E. coli toward multidrug resistance.
    Antimicrob Agents Chemother. 2024;68:e0133923.
    PubMed     Abstract available


  36. MARTISCHANG R, Seth-Smith H, Verschuuren TD, Hequet D, et al
    Regional spread of an atypical ESBL-producing Escherichia coli ST131H89 clone among different human and environmental reservoirs in Western Switzerland.
    Antimicrob Agents Chemother. 2024;68:e0092523.
    PubMed     Abstract available


  37. LEPAK AJ, VanScoy B, Rubino C, Ambrose PG, et al
    In vivo pharmacodynamic characterization of a next-generation polyene, SF001, in the invasive pulmonary aspergillosis mouse model.
    Antimicrob Agents Chemother. 2024 Feb 6:e0163123. doi: 10.1128/aac.01631.
    PubMed     Abstract available


  38. CARUGATI M, Arif S, Yarrington ME, King LY, et al
    Limitations of antifungal prophylaxis in preventing invasive Candida surgical site infections after liver transplant surgery.
    Antimicrob Agents Chemother. 2024 Feb 1:e0127923. doi: 10.1128/aac.01279.
    PubMed     Abstract available


    January 2024
  39. AXELL-HOUSE DB, Simar SR, Panesso D, Rincon S, et al
    LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Jan 30:e0106923. doi: 10.1128/aac.01069.
    PubMed     Abstract available


  40. JIANG X, Li D, Sun Z, Lu Y, et al
    Type I BREX system defends against antibiotic-resistant plasmids in Escherichia coli.
    Antimicrob Agents Chemother. 2024 Jan 30:e0112823. doi: 10.1128/aac.01128.
    PubMed     Abstract available


  41. IOVLEVA A, McElheny CL, Fowler EL, Cober E, et al
    In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals.
    Antimicrob Agents Chemother. 2024 Jan 30:e0125823. doi: 10.1128/aac.01258.
    PubMed     Abstract available


  42. LIU X, Wang Y, Chang W, Dai Y, et al
    AgrA directly binds to the promoter of vraSR and downregulates its expression in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2024 Jan 23:e0089323. doi: 10.1128/aac.00893.
    PubMed     Abstract available


  43. CHEN F, Yin Y, Chen H, Wang R, et al
    Global genetic diversity and Asian clades evolution: a phylogeographic study of Staphylococcus aureus sequence type 5.
    Antimicrob Agents Chemother. 2024 Jan 23:e0117523. doi: 10.1128/aac.01175.
    PubMed     Abstract available


  44. TRUONG-BOLDUC QC, Yonker LM, Wang Y, Lawton BG, et al
    NorA efflux pump mediates Staphylococcus aureus response to Pseudomonas aeruginosa pyocyanin toxicity.
    Antimicrob Agents Chemother. 2024 Jan 17:e0100123. doi: 10.1128/aac.01001.
    PubMed     Abstract available


  45. ALDEJOHANN AM, Menner C, Thielemann N, Martin R, et al
    In vitro activity of ibrexafungerp against clinically relevant echinocandin-resistant Candida strains.
    Antimicrob Agents Chemother. 2024 Jan 11:e0132423. doi: 10.1128/aac.01324.
    PubMed     Abstract available


  46. PEARLMUTTER BS, Carlisle MG, Wilson BM, Sangwan N, et al
    Pulsed dosing and extended daily dosing of oral vancomycin do not facilitate clearance of Clostridioides difficile colonization in mice.
    Antimicrob Agents Chemother. 2024;68:e0090323.
    PubMed     Abstract available


  47. WANG X, Chen L, Ruan H, Xiong Z, et al
    Oteseconazole versus fluconazole for the treatment of severe vulvovaginal candidiasis: a multicenter, randomized, double-blinded, phase 3 trial.
    Antimicrob Agents Chemother. 2024;68:e0077823.
    PubMed     Abstract available


  48. GHASSANI A, Triponney P, Bour M, Plesiat P, et al
    Mutations in genes lpxL1, bamA, and pmrB impair the susceptibility of cystic fibrosis strains of Pseudomonas aeruginosa to murepavadin.
    Antimicrob Agents Chemother. 2024;68:e0129823.
    PubMed     Abstract available


  49. BREIDENSTEIN EBM, Khan N, Duffy T, Coward C, et al
    SMT-738: a novel small-molecule inhibitor of bacterial lipoprotein transport targeting Enterobacteriaceae.
    Antimicrob Agents Chemother. 2024;68:e0069523.
    PubMed     Abstract available


  50. BERMUDEZ TA, Brannon JR, Dudipala N, Reasoner S, et al
    Raising the alarm: fosfomycin resistance associated with non-susceptible inner colonies imparts no fitness cost to the primary bacterial uropathogen.
    Antimicrob Agents Chemother. 2024;68:e0080323.
    PubMed     Abstract available


  51. TERAN N, Egge SL, Phe K, Baptista RP, et al
    The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy.
    Antimicrob Agents Chemother. 2024;68:e0100923.
    PubMed     Abstract available


  52. NOVY E, Abdul-Aziz MH, Cheng V, Burrows F, et al
    Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study.
    Antimicrob Agents Chemother. 2024;68:e0120123.
    PubMed     Abstract available


  53. GOMIS-FONT MA, Clari MA, Lopez-Causape C, Navarro D, et al
    Emergence of cefiderocol resistance during ceftazidime/avibactam treatment caused by a large genomic deletion, including ampD and piuCD genes, in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024;68:e0119223.
    PubMed     Abstract available


  54. KIRKLAND ME, Patfield S, Hughes AC, Hernlem B, et al
    A novel Shiga toxin 2a neutralizing antibody therapeutic with low immunogenicity and high efficacy.
    Antimicrob Agents Chemother. 2024;68:e0059823.
    PubMed     Abstract available


  55. ARAGAW WW, Negatu DA, Bungard CJ, Dartois VA, et al
    Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2024;68:e0071723.
    PubMed     Abstract available


  56. CHEN T, Yao J, Quan K, Xu J, et al
    Repurposing a human acetyl-CoA carboxylase inhibitor firsocostat to treat fungal candidiasis alone and in combination.
    Antimicrob Agents Chemother. 2024;68:e0113123.
    PubMed     Abstract available


  57. SINGH P, Kumar A, Sharma P, Chugh S, et al
    Identification and optimization of pyridine carboxamide-based scaffold as a drug lead for Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2024 Jan 9:e0076623. doi: 10.1128/aac.00766.
    PubMed     Abstract available


  58. TAYLOR E, Nailor MD, Feider M, Sullivan S, et al
    Doxycycline versus cephalexin treatment of presumed streptococcal skin and soft tissue infection among adults presenting to the emergency department.
    Antimicrob Agents Chemother. 2024 Jan 3:e0128223. doi: 10.1128/aac.01282.
    PubMed     Abstract available


    December 2023
  59. RUELAS CASTILLO J, Neupane P, Karanika S, Krug S, et al
    The heme oxygenase-1 metalloporphyrin inhibitor stannsoporfin enhances the bactericidal activity of a novel regimen for multidrug-resistant tuberculosis in a murine model.
    Antimicrob Agents Chemother. 2023 Dec 22:e0104323. doi: 10.1128/aac.01043.
    PubMed     Abstract available


  60. SINGH S, Gumbo T, Boorgula GD, Thomas TA, et al
    Omadacycline pharmacokinetics/pharmacodynamics and efficacy against multidrug-resistant Mycobacterium tuberculosis in the hollow fiber system model.
    Antimicrob Agents Chemother. 2023 Dec 22:e0108023. doi: 10.1128/aac.01080.
    PubMed     Abstract available


  61. ALI AM, P Solans B, Hesseling AC, Winckler J, et al
    Pharmacokinetics and cardiac safety of clofazimine in children with rifampicin-resistant tuberculosis.
    Antimicrob Agents Chemother. 2023 Dec 19:e0079423. doi: 10.1128/aac.00794.
    PubMed     Abstract available


  62. STEMKENS R, Cobussen M, de Laat E, Hoefsloot W, et al
    Successful addition of topical antibiotic treatment after surgery in treatment-refractory nontuberculous mycobacterial skin and soft tissue infections.
    Antimicrob Agents Chemother. 2023;67:e0078823.
    PubMed     Abstract available


  63. ROEPCKE S, Passarell J, Walker H, Flanagan S, et al
    Population pharmacokinetic modeling and target attainment analyses of rezafungin for the treatment of candidemia and invasive candidiasis.
    Antimicrob Agents Chemother. 2023;67:e0091623.
    PubMed     Abstract available


  64. NGUYEN DC, Buettner AM, Dousa KM
    Case Commentary: Another prong of attack? Topical antibiotic instillation with negative pressure wound therapy for nontuberculous mycobacterial skin and soft tissue infections.
    Antimicrob Agents Chemother. 2023;67:e0104823.
    PubMed     Abstract available


  65. ROHANI R, Yarnold PR, Scheetz MH, Neely MN, et al
    Individual meropenem epithelial lining fluid and plasma PK/PD target attainment.
    Antimicrob Agents Chemother. 2023;67:e0072723.
    PubMed     Abstract available


  66. KADO J, Salman S, Hla TK, Enkel S, et al
    Subcutaneous infusion of high-dose benzathine penicillin G is safe, tolerable, and suitable for less-frequent dosing for rheumatic heart disease secondary prophylaxis: a phase 1 open-label population pharmacokinetic study.
    Antimicrob Agents Chemother. 2023;67:e0096223.
    PubMed     Abstract available


  67. LERMINIAUX N, Mitchell R, Bartoszko J, Davis I, et al
    Plasmid genomic epidemiology of bla(KPC) carbapenemase-producing Enterobacterales in Canada, 2010-2021.
    Antimicrob Agents Chemother. 2023;67:e0086023.
    PubMed     Abstract available


  68. FERNANDEZ LEDESMA B, Mendoza-Palomar N, Melendo Perez S, Fernandez-Polo A, et al
    Isavuconazole use and TDM in real-world pediatric practice.
    Antimicrob Agents Chemother. 2023;67:e0082923.
    PubMed     Abstract available


  69. COBIAN GUEMES AG, Ghatbale P, Blanc AN, Morgan CJ, et al
    Jumbo phages are active against extensively drug-resistant eyedrop-associated Pseudomonas aeruginosa infections.
    Antimicrob Agents Chemother. 2023;67:e0065423.
    PubMed     Abstract available


  70. SASONI N, Caracciolo B, Cabeza MS, Gamarra S, et al
    Antifungal susceptibility testing following the CLSI M27 document, along with the measurement of MFC/MIC ratio, could be the optimal approach to detect amphotericin B resistance in Clavispora (Candida) lusitaniae. Susceptibility patterns of contempora
    Antimicrob Agents Chemother. 2023 Dec 12:e0096823. doi: 10.1128/aac.00968.
    PubMed     Abstract available


  71. JAROMIN A, Zarnowski R, Markowski A, Zagorska A, et al
    Liposomal formulation of a new antifungal hybrid compound provides protection against Candida auris in the ex vivo skin colonization model.
    Antimicrob Agents Chemother. 2023 Dec 11:e0095523. doi: 10.1128/aac.00955.
    PubMed     Abstract available


  72. LIU S, Huang Y, Jensen S, Laman P, et al
    Molecular physiological characterization of the dynamics of persister formation in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Dec 5:e0085023. doi: 10.1128/aac.00850.
    PubMed     Abstract available


  73. HAN D, Ji Y, Yang S, Song P, et al
    Therapeutic effect of iturin A on Candida albicans oral infection and its pathogenic factors.
    Antimicrob Agents Chemother. 2023 Dec 5:e0094823. doi: 10.1128/aac.00948.
    PubMed     Abstract available


  74. PANDEY S, Vilcheze C, Werngren J, Bainomugisa A, et al
    Loss-of-function mutations in ndh do not confer delamanid, ethionamide, isoniazid, or pretomanid resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2023 Dec 1:e0109623. doi: 10.1128/aac.01096.
    PubMed     Abstract available


    November 2023
  75. ZHAO J, Pu D, Li Z, Liu X, et al
    In vitro activity of cefiderocol, a siderophore cephalosporin, against carbapenem-resistant hypervirulent Klebsiella pneumoniae in China.
    Antimicrob Agents Chemother. 2023 Nov 28:e0073523. doi: 10.1128/aac.00735.
    PubMed     Abstract available


  76. JIAO F, Bao Y, Li M, Zhang Y, et al
    Unraveling the mechanism of ceftaroline-induced allosteric regulation in penicillin-binding protein 2a: insights for novel antibiotic development against methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Nov 16:e0089523. doi: 10.1128/aac.00895.
    PubMed     Abstract available


  77. VAN DER LAAN LE, Garcia-Prats AJ, McIlleron H, Abdelwahab MT, et al
    Optimizing dosing of the cycloserine pro-drug terizidone in children with rifampicin-resistant tuberculosis.
    Antimicrob Agents Chemother. 2023 Nov 16:e0061123. doi: 10.1128/aac.00611.
    PubMed     Abstract available


  78. SVISHCHUK J, Ebbert K, Waddell B, Izydorczyk C, et al
    Epidemiology and impact of methicillin-sensitive Staphylococcus aureus with beta-lactam antibiotic inoculum effects in adults with cystic fibrosis.
    Antimicrob Agents Chemother. 2023 Nov 15:e0013623. doi: 10.1128/aac.00136.
    PubMed     Abstract available


  79. LANNI F, Antilus Sainte R, Hansen M Jr, Parigi P, et al
    A preclinical model of TB meningitis to determine drug penetration and activity at the sites of disease.
    Antimicrob Agents Chemother. 2023 Nov 15:e0067123. doi: 10.1128/aac.00671.
    PubMed     Abstract available


  80. ALMEIDA D, Li S-Y, Lee J, Hafkin B, et al
    Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis.
    Antimicrob Agents Chemother. 2023 Nov 15:e0078923. doi: 10.1128/aac.00789.
    PubMed     Abstract available


  81. DIAZ-GARCIA J, Machado M, Alcala L, Reigadas E, et al
    Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022.
    Antimicrob Agents Chemother. 2023;67:e0098623.
    PubMed     Abstract available


  82. CASADO A, Gimeno A, Aguilar-Guisado M, Garcia M, et al
    Safety of early oral ambulatory treatment of adult patients with bloodstream infections discharged from the emergency department.
    Antimicrob Agents Chemother. 2023;67:e0078023.
    PubMed     Abstract available


  83. RUIZ VH, Fratoni A, Nicolau DP, Kuti JL, et al
    In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolated from patients with cystic fibrosis.
    Antimicrob Agents Chemother. 2023;67:e0092023.
    PubMed     Abstract available


  84. HARDY ME, Kenney RM, Tibbetts RJ, Shallal AB, et al
    Leveraging stewardship to promote ceftriaxone use in severe infections with low- and no-risk AmpC Enterobacterales.
    Antimicrob Agents Chemother. 2023;67:e0082623.
    PubMed     Abstract available


  85. EL GHALI A, Stamper K, Kunz Coyne AJ, Holger D, et al
    Ciprofloxacin in combination with bacteriophage cocktails against multi-drug resistant Pseudomonas aeruginosa in ex vivo simulated endocardial vegetation models.
    Antimicrob Agents Chemother. 2023;67:e0072823.
    PubMed     Abstract available


  86. SCHILDKRAUT JA, Raaijmakers J, Aarnoutse R, Hoefsloot W, et al
    The role of rifampicin within the treatment of Mycobacterium avium pulmonary disease.
    Antimicrob Agents Chemother. 2023;67:e0087423.
    PubMed     Abstract available


  87. LIM SY, Kwon HJ, Lee YW, Sung H, et al
    Routine ophthalmologic examination in Klebsiella pneumoniae bacteremia is not necessary: incidence of and risk factors for ocular involvement.
    Antimicrob Agents Chemother. 2023;67:e0082223.
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    Case Commentary: An espresso, a free puppy, and multidrug-resistant Campylobacter.
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