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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Bacterial Infections and Mycoses

Free Subscription Articles published in Antimicrob Agents Chemother Retrieve available abstracts of 469 articles: HTML format

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June 2008
1. DESNOS-OLLIVIER M , Bretagne S, Raoux D, Hoinard D, et al
   Mutations in the fks1 gene in Candida albicans, C. tropicalis and C. krusei correlate with elevated caspofungin MICs uncovered in AM3 medium using the EUCAST method.
   Antimicrob Agents Chemother. 2008;.
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2. ROSE WE , Leonard SN, Rybak MJ
   Evaluation of daptomycin pharmacodynamics and resistance at varying dosage regimens against Staphylococcus aureus with reduced susceptibilities to daptomycin in an in-vitro pharmacodynamic model with simulated endocardial vegetations.
   Antimicrob Agents Chemother. 2008;.
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3. MESAK LR , Miao V, Davies J
   The effects of sub-inhibitory concentrations of antibiotics on SOS and DNA repair gene expression in Staphylococcus aureus.
   Antimicrob Agents Chemother. 2008;.
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4. HAZBON MH , Motiwala AS, Cavatore M, Brimacombe M, et al
   Convergent evolutionary analysis identifies significant mutations in drug resistance targets of Mycobacterium tuberculosis.
   Antimicrob Agents Chemother. 2008;.
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5. GYGAX SE , Vermitsky JP, Chadwick SG, Self MJ, et al
   Antifungal Resistance of Candida glabrata Vaginal Isolates and the Development of a qRT-PCR-based Azole Susceptibility Assay.
   Antimicrob Agents Chemother. 2008;.
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6. AMRINE-MADSEN H , Van Eldere J, Mera RM, Miller LA, et al
   Temporal and Spatial Distribution of Clonal Complexes of Streptococcus pneumoniae Resistant to Multiple Classes of Antibiotics in Belgium, 1997-2004.
   Antimicrob Agents Chemother. 2008;.
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7. NETT JE , Guite KM, Ringeisen A, Holoyda KA, et al
   Reduced Biocide Susceptibility in Candida albicans Biofilms.
   Antimicrob Agents Chemother. 2008;.
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8. MOKROUSOV I , Otten T, Manicheva O, Potapova Y, et al
   Molecular characterization of ofloxacin-resistant Mycobacterium tuberculosis strains from Russia.
   Antimicrob Agents Chemother. 2008;.
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9. STEIDL R , Pearson S, Stephenson RE, Ledala N, et al
   Staphylococcus aureus Cell Wall Stress Stimulon Gene-lacZ Fusion Strains: Potential for Use in Screening for Cell Wall-Active Antimicrobials.
   Antimicrob Agents Chemother. 2008;.
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10. SPIES FS , Almeida da Silva PE, Ribeiro MO, Rossetti ML, et al
    Identification of mutations related to streptomycin resistance in clinical isolates of Mycobacterium tuberculosis and possible involvement of efflux mechanism.
    Antimicrob Agents Chemother. 2008;.
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11. DAHESH S , Hensler ME, Van Sorge NM, Gertz RE Jr, et al
    Point Mutation in the Group B Streptococcal pbp2x Gene Conferring Decreased Susceptibility to Beta-Lactam Antibiotics.
    Antimicrob Agents Chemother. 2008;.
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12. LEMAIRE S , Olivier A, Van Bambeke F, Tulkens PM, et al
    Restoration of susceptibility of intracellular Methicillin Resistant Staphylococcus aureus (MRSA) to {beta}-lactams: comparison between strains, cells, and antibiotics.
    Antimicrob Agents Chemother. 2008;.
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13. ACHARD A , Guerin-Faublee V, Pichereau V, Villers C, et al
    Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like Gene.
    Antimicrob Agents Chemother. 2008;.
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14. KOGA T , Masuda N, Kakuta M, Namba E, et al
    Potent in Vitro Activity of Tomopenem (CS-023) against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2008;.
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15. LEONARD SN , Cheung CM, Rybak MJ
    Evaluation of the activity of ceftobiprole, linezolid, vancomycin, and daptomycin against Community-associated (CA-MRSA) and Hospital-associated (HA-MRSA) methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2008;.
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16. BOWKER KE , Noel AR, Macgowan AP
    The pharmacodynamics of minocycline against Staphylococcus aureus in an invitro pharmacokinetic model.
    Antimicrob Agents Chemother. 2008;.
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17. KEITH ER , Murdoch DR
    Antimicrobial Susceptibility Profile of Streptococcus pseudopneumoniae Isolated from Sputum.
    Antimicrob Agents Chemother. 2008;.
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    May 2008
18. DIAS R , Felix D, Canica M
    Diversity of Penicillin Binding Proteins from Streptococcus pneumoniae among Portuguese clinical strains.
    Antimicrob Agents Chemother. 2008;.
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19. SCHWAIGER K , Bauer J
    Detection of the Erythromycin Ribosomal RNA Methylase Gene erm(A) in Enterococcus faecalis.
    Antimicrob Agents Chemother. 2008;.
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20. RUSTOMJEE R , Diacon AH, Allen J, Venter A, et al
    Early bactericidal activity and pharmacokinetics of the Diarylquinoline TMC 207 in pulmonary tuberculosis.
    Antimicrob Agents Chemother. 2008;.
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21. KIMURA K , Suzuki S, Wachino JI, Kurokawa H, et al
    First Molecular Characterization of Group B Streptococci with Reduced Penicillin Susceptibility.
    Antimicrob Agents Chemother. 2008;.
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22. HOSHI S , Kikuchi K, Sasaki T, Sotozono C, et al
    Postantibiotic effects and bactericidal activities of simulated topical ophthalmic administration of levofloxacin and gatifloxacin against fluoroquinolone-resistant and fluoroquinolone-sensitive methicillin-resistant Staphylococcus aureus strains.
    Antimicrob Agents Chemother. 2008;.
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23. YONEZAWA H , Kuramitsu HK, Nakayama SI, Mitobe J, et al
    Differential expression of the Smb bacteriocin in Streptococcus mutans isolates.
    Antimicrob Agents Chemother. 2008;.
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24. VALLOR AC , Kirkpatrick WR, Najvar LK, Bocanegra R, et al
    Assessment of Pulmonary Aspergillus fumigatus Tissue Burden by Quantitative PCR, Galactomannan EIA and Quantitative Culture in Guinea pigs.
    Antimicrob Agents Chemother. 2008;.
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25. RIEDEL DJ , Weekes E, Forrest GN
    Addition of Rifampin to Standard Therapy for Treatment of Native Valve Staphylococcus aureus Infective Endocarditis.
    Antimicrob Agents Chemother. 2008;.
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26. RODRIGUEZ-TUDELA JL , Alcazar-Fuoli L, Mellado E, Alastruey-Izquierdo A, et al
    Epidemiological cut-offs and cross-resistance to azole drugs in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2008;.
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27. RUAN SY , Chu CC, Hsueh PR
    In Vitro Susceptibility of Invasive Isolates of Candida Species: Rapid Increase in Rates of Fluconazole Susceptible-Dose Dependent Candida glabrata.
    Antimicrob Agents Chemother. 2008;.
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28. BOYD DA , Willey BM, Fawcett D, Gillani N, et al
    Molecular characterization of low level vancomycin resistant Enterococcus faecalis N06-0364 harboring a novel D-Ala-D-Ser gene cluster, vanL.
    Antimicrob Agents Chemother. 2008;.
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29. DANILCHANKA O , Mailaender C, Niederweis M
    Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2008;.
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    April 2008
30. AL-NASSIR WN , Sethi AK, Li Y, Pultz MJ, et al
    Both oral metronidazole and oral vancomycin promote persistent overgrowth of vancomycin-resistant enterococci during treatment of Clostridium difficile-associated disease.
    Antimicrob Agents Chemother. 2008;.
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31. CRITCHLEY IA , Jacobs MR, Brown SD, Traczewski MM, et al
    Prevalence of Serotype 19A Streptococcus pneumoniae among Isolates from U.S. Children in 2005-2006 and Activity of Faropenem.
    Antimicrob Agents Chemother. 2008;.
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32. KARPANOJA P , Nyberg ST, Bergman M, Voipio T, et al
    The Connection between Trimethoprim-sulfamethoxazole Use and Resistance in Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis.
    Antimicrob Agents Chemother. 2008;.
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33. GARCIA-EFFRON G , Katiyar SK, Park S, Edlind TD, et al
    A Naturally-Occurring Fks1p Proline to Alanine Amino Acid Change in Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis Accounts for Reduced Echinocandin Susceptibility.
    Antimicrob Agents Chemother. 2008;.
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34. ROBERTSON GT , Bonventre EJ, Doyle TB, Du Q, et al
    In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2008;.
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35. ROBERTSON GT , Bonventre EJ, Doyle TB, Du Q, et al
    In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Microbiology Profiling Studies Undertaken in Staphylococci and Streptococci.
    Antimicrob Agents Chemother. 2008;.
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36. MATRAT S , Aubry A, Mayer C, Jarlier V, et al
    Mutagenesis in the {alpha}3{alpha}4 GyrA Helix and in the Toprim domain of GyrB Refines the Contribution of Mycobacterium tuberculosis DNA Gyrase to Intrinsic Resistance to Quinolones.
    Antimicrob Agents Chemother. 2008;.
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37. MARCO F , de la Maria CG, Armero Y, Amat E, et al
    Daptomycin Is Effective in the Treatment of Experimental Endocarditis Due to Methicillin-Resistant and Glycopeptide-Intermediate Staphylococcus aureus.
    Antimicrob Agents Chemother. 2008;.
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38. PAI MP , Samples ML, Mercier RC, Spilde MN, et al
    Activity and Ultrastructural Effects of Antifungal Combinations against Simulated Candida Endocardial Vegetations.
    Antimicrob Agents Chemother. 2008;.
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39. MEZGER M , Wozniok I, Blockhaus C, Kurzai O, et al
    Impact of Mycophenolic Acid on the Functionality of Human Polymorphonuclear Neutrophils and Dendritic Cells during Interaction with Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2008;.
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40. HSIEH YC , Chang KY, Huang YC, Lin HC, et al
    Clonal Spread of Highly {beta}-Lactam-Resistant Streptococcus pneumoniae in Taiwan.
    Antimicrob Agents Chemother. 2008;.
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41. LAOHAVALEESON S , Tessier PR, Nicolau DP
    Pharmacodynamic Characterization of Ceftobiprole in Experimental Pneumonia Caused by Phenotypically Diverse Staphylococcus aureus.
    Antimicrob Agents Chemother. 2008;.
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42. LAPLANTE KL , Leonard SN, Andes DR, Craig WA, et al
    Activity of Clindamycin Inducible Resistant Community Associated Methicillin Staphylococcus aureus versus Clindamycin, Daptomycin, Doxycycline, Linezolid, Trimethoprim/sulfamethoxazole and Vancomycin in Murine Thigh-Infection and In Vitro Pharmacodynamic
    Antimicrob Agents Chemother. 2008;.
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43. SATER AA , Ojcius DM, Meyer MP
    Susceptibility of Chlamydia trachomatis to the excipient hydroxy-ethylcellulose: pH and concentration dependence of antimicrobial activity.
    Antimicrob Agents Chemother. 2008;.
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44. SIMONETTI O , Cirioni O, Ghiselli R, Goteri G, et al
    RIP ENHANCES HEALING OF WOUNDS INFECTED WITH METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS.
    Antimicrob Agents Chemother. 2008;.
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45. YAMADA M , Watanabe T, Baba N, Takeuchi Y, et al
    Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae.
    Antimicrob Agents Chemother. 2008;.
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46. SPREGHINI E , Maida CM, Tomassetti S, Orlando F, et al
    Posaconazole against Candida glabrata with Variable Susceptibility to Fluconazole.
    Antimicrob Agents Chemother. 2008;.
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47. IZQUIERDO E , Bednarczyk A, Schaeffer C, Cai Y, et al
    Production of Enterocins L50A, L50B, and the New IT by Enterococcus faecium IT62, a Strain Isolated from Italian Ryegrass in Japan.
    Antimicrob Agents Chemother. 2008;.
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48. KIHARA R , Yanagihara K, Morinaga Y, Araki N, et al
    Potency of SMP-601, a novel carbapenem, in hematogenous murine bronchopneumonia caused by methicillin-resistant and vancomycin-intermediate Staphylococcus aureus.
    Antimicrob Agents Chemother. 2008;.
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49. MENDES RE , Deshpande LM, Castanheira M, Dipersio J, et al
    First Report of cfr-mediated Resistance to Linezolid in Human Staphylococcal Clinical Isolates Recovered in the United States.
    Antimicrob Agents Chemother. 2008;.
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50. JACOBSON MJ , Piper KE, Nguyen G, Steckelberg JM, et al
    In vitro Activity of Anidulafungin against Candida albicans Biofilms.
    Antimicrob Agents Chemother. 2008;.
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51. HUANG TS , Liu YC, Sy CL, Chen YS, et al
    In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis complex Isolated in Taiwan over Ten Years.
    Antimicrob Agents Chemother. 2008;.
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52. SCHEETZ MH , Knechtel S, Malczynski M, Postelnick MJ, et al
    Increasing Incidence of Linezolid Intermediate or Resistant, Vancomycin-Resistant Enterococcus faecium (LIRVREF) Parallels Increasing Linezolid Consumption.
    Antimicrob Agents Chemother. 2008;.
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53. WILKINS JJ , Savic RM, Karlsson MO, Langdon G, et al
    Population pharmacokinetics of rifampin in pulmonary tuberculosis patients including a semi-mechanistic model to describe variable absorption.
    Antimicrob Agents Chemother. 2008;.
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54. CASTANHEIRA M , Fritsche TR, Sader HS, Jones RN, et al
    RmtD 16S RNA methylase in epidemiologically unrelated spm-1-producing Pseudomonas aeruginosa isolates from Brazil.
    Antimicrob Agents Chemother. 2008;52:1587-8.
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55. YAMANE K , Wachino J, Suzuki S, Arakawa Y, et al
    Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan.
    Antimicrob Agents Chemother. 2008;52:1564-6.
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56. DAW-GARZA A , Welsh O, Said-Fernandez S, Lozano-Garza HG, et al
    In vivo therapeutic effect of gatifloxacin on BALB/c mice infected with Nocardia brasiliensis.
    Antimicrob Agents Chemother. 2008;52:1549-50.
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57. SHUE YK , Sears PS, Shangle S, Walsh RB, et al
    Safety, tolerance, and pharmacokinetic studies of OPT-80 in healthy volunteers following single and multiple oral doses.
    Antimicrob Agents Chemother. 2008;52:1391-5.
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58. MITSUYAMA J , Nomura N, Hashimoto K, Yamada E, et al
    In vitro and in vivo antifungal activities of T-2307, a novel arylamidine.
    Antimicrob Agents Chemother. 2008;52:1318-24.
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59. NAAS T , Cuzon G, Villegas MV, Lartigue MF, et al
    Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene.
    Antimicrob Agents Chemother. 2008;52:1257-63.
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60. IBRAHIM AS , Gebremariam T, Husseiny MI, Stevens DA, et al
    Comparison of lipid amphotericin B preparations in treating murine zygomycosis.
    Antimicrob Agents Chemother. 2008;52:1573-6.
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61. MEZIANE-CHERIF D , Lambert T, Dupechez M, Courvalin P, et al
    Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442.
    Antimicrob Agents Chemother. 2008;52:1264-8.
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62. SOUMMER A , Mathonnet A, Scatton O, Massault PP, et al
    Failure of deferasirox, an iron chelator agent, combined with antifungals in a case of severe zygomycosis.
    Antimicrob Agents Chemother. 2008;52:1585-6.
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63. IBRAHIM AS , Gebremariam T, Fu Y, Edwards JE Jr, et al
    Combination echinocandin-polyene treatment of murine mucormycosis.
    Antimicrob Agents Chemother. 2008;52:1556-8.
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64. CRUMP JA , Kretsinger K, Gay K, Hoekstra RM, et al
    Clinical response and outcome of infection with Salmonella enterica serotype Typhi with decreased susceptibility to fluoroquinolones: a United States foodnet multicenter retrospective cohort study.
    Antimicrob Agents Chemother. 2008;52:1278-84.
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65. ILLNAIT-ZARAGOZI MT , Martinez GF, Curfs-Breuker I, Fernandez CM, et al
    In Vitro activity of the new azole isavuconazole (BAL4815) compared with six other antifungal agents against 162 Cryptococcus neoformans isolates from Cuba.
    Antimicrob Agents Chemother. 2008;52:1580-2.
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    March 2008
66. MILLER K , O'Neill AJ, Wilcox MH, Ingham E, et al
    Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents.
    Antimicrob Agents Chemother. 2008;.
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67. CLEARY JD , Garcia-Effron G, Chapman SW, Perlin DS, et al
    Reduced Candida glabrata Susceptibility Secondary to a FKS1 Mutation Developed During Candidemia Treatment.
    Antimicrob Agents Chemother. 2008;.
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68. SAFI H , Sayers B, Hazbon MH, Alland D, et al
    Transfer of embB306 mutations into clinical Mycobacterium tuberculosis alters susceptibility to ethambutol, isoniazid and rifampin.
    Antimicrob Agents Chemother. 2008;.
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69. COTRONEO N , Harris R, Perlmutter N, Beveridge T, et al
    Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus.
    Antimicrob Agents Chemother. 2008;.
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70. REINERT RR , Filimonova OY, Al-Lahham A, Grudinina SA, et al
    Characterization of the Mechanisms of Macrolide-Resistance among Streptococcus pneumoniae Isolates from Russia.
    Antimicrob Agents Chemother. 2008;.
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71. BESIER S , Zander J, Kahl BC, Kraiczy P, et al
    The thymidine-dependent small colony variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates.
    Antimicrob Agents Chemother. 2008;.
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72. FIRSOV AA , Lubenko IY, Smirnova MV, Strukova EN, et al
    Enrichment of Fluoroquinolone Resistant Staphylococcus aureus: Oscillating Ciprofloxacin Concentrations Simulated at the Upper and Lower Portions of the Mutant Selection Window.
    Antimicrob Agents Chemother. 2008;.
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73. BANERJEE R , Gretes M, Basuino L, Strynadka N, et al
    In vitro Selection and Characterization of Ceftobiprole-Resistant Methicillin Resistant Staphylococcus aureus (MRSA).
    Antimicrob Agents Chemother. 2008;.
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74. GARVEY MI , Piddock LJ
    The efflux pump inhibitor reserpine selects multidrug resistant Streptococcus pneumoniae that over-express the ABC transporters PatA and PatB.
    Antimicrob Agents Chemother. 2008;.
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75. HIGASHIDE M , Kuroda M, Omura CT, Kumano M, et al
    Methicillin-resistant Staphylococcus saprophyticus Carrying Staphylococcal Cassette Chromosome mec (SCCmec) Have Emerged in Urogenital Tract Infections.
    Antimicrob Agents Chemother. 2008;.
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76. DE LA PEDROSA EG , Morosini MI, van der Linden M, Ruiz-Garbajosa P, et al
    Polyclonal Population Structure of mef and mef plus erm(B) Streptococcus pneumoniae isolates in Spain.
    Antimicrob Agents Chemother. 2008;.
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77. ALFFENAAR JW , de Vries PM, Luijckx GJ, van Soolingen D, et al
    Plasma and CSF pharmacokinetics of moxifloxacin in a patient with tuberculous meningitis.
    Antimicrob Agents Chemother. 2008;.
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78. PERKHOFER S , Jost D, Dierich MP, Lass-Florl C, et al
    Susceptibility Testing of Anidulafungin and Voriconazole Alone and in Combination Against Conidia and Hyphae of Aspergillus spp. under Hypoxic Conditions.
    Antimicrob Agents Chemother. 2008;.
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79. YAMAGUCHI H , Kamiya S, Uruma T, Osaki T, et al
    Chlamydia pneumoniae Growth Inhibition in Cells by Steroid Receptor Antagonist RU486 Mifepristone.
    Antimicrob Agents Chemother. 2008;.
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80. MANTOVANI HC , Russell JB
    Bovicin HC5, a lantibiotic produced by Streptococcus bovis HC5, catalyzed the efflux of intracellular potassium but not ATP.
    Antimicrob Agents Chemother. 2008;.
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81. YIN LY , Calhoun JH, Thomas JK, Shapiro S, et al
    Efficacies of Ceftobiprole Medocaril and Comparators in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
    Antimicrob Agents Chemother. 2008;.
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82. BALTCH AL , Ritz WJ, Bopp LH, Michelsen P, et al
    Activities of Daptomycin and Comparative Antimicrobials, Singly and in Combination, against Extracellular and Intracellular Staphylococcus aureus and its Stable Small Colony Variant (SCV) in Human Monocyte-derived Macrophages and in Broth.
    Antimicrob Agents Chemother. 2008;.
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83. PICHICHERO ME , Casey JR, Block SL, Guttendorf R, et al
    Pharmacodynamic Analysis and Clinical Trial of Amoxicillin Sprinkle QD for 7 Days Compared to Penicillin VK QID for 10 Days in the Treatment of Tonsillopharyngitis due to Streptococcus Pyogenes in Children.
    Antimicrob Agents Chemother. 2008;.
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84. CAMPBELL LA , Kuo CC, Suchland RJ, Rothstein DM, et al
    Efficacy of Benzoxazinorifamycins in the Mouse Model of Chlamydia pneumoniae Lung Infection.
    Antimicrob Agents Chemother. 2008;.
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85. WEBER K , Sohr R, Schulz B, Fleischhacker M, et al
    Secretion of E,E-farnesol and biofilm formation in eight different Candida species.
    Antimicrob Agents Chemother. 2008;.
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86. STEINBERG D , Moreinos D, Featherstone J, Shemesh M, et al
    Genetic and physiological effects of noncoherent visible light combined with hydrogen peroxide on Streptococcus mutans in biofilm.
    Antimicrob Agents Chemother. 2008;.
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87. JUREEN P , Werngren J, Toro JC, Hoffner S, et al
    Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2008;.
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    February 2008
88. STERGIOPOULOU T , Meletiadis J, Sein T, Papaioannidou P, et al
    Isobolographic analysis of pharmacodynamic interactions between antifungal agents and ciprofloxacin against Candida albicans and Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2008;.
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89. KAKEYA H , Miyazaki Y, Senda H, Kobayashi T, et al
    Efficacy of SPK-843, a Novel Polyene Antifungal in Murine Pulmonary Aspergillosis in Comparison with Amphotericin B, AmBisome(R) and Micafungin.
    Antimicrob Agents Chemother. 2008;.
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90. WU HM , Janapatla RP, Ho YR, Hung KH, et al
    Emergence of Fluoroquinolone Resistance in Group B Streptococcal Isolates in Taiwan.
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