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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in J Clin Endocrinol Metab

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Single Articles


    May 2008
  1. NEUMANN HP , Erlic Z
    Maternal transmission of symptomatic disease with SDHD mutation: fact or fiction?
    J Clin Endocrinol Metab. 2008;93:1573-5.
    PubMed     Related articles   


  2. KLOOS RT
    Approach to the patient with a positive serum thyroglobulin and a negative radioiodine scan after initial therapy for differentiated thyroid cancer.
    J Clin Endocrinol Metab. 2008;93:1519-25.
    PubMed     Related articles    Abstract available


  3. PIGNY P , Vincent A, Cardot Bauters C, Bertrand M, et al
    Paraganglioma after maternal transmission of a succinate dehydrogenase gene mutation.
    J Clin Endocrinol Metab. 2008;93:1609-15.
    PubMed     Related articles    Abstract available


    April 2008
  4. MIYAUCHI A , Takamura Y, Ito Y, Miya A, et al
    T3 Thyrotoxicosis Due to Increased Conversion of Administered Levothyroxine in Patients with Massive Metastatic Follicular Thyroid Carcinoma.
    J Clin Endocrinol Metab. 2008;.
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  5. BRABANT G
    Thyrotropin suppressive therapy in thyroid carcinoma: what are the targets?
    J Clin Endocrinol Metab. 2008;93:1167-9.
    PubMed     Related articles   


  6. WEBER F , Eng C
    Update on the molecular diagnosis of endocrine tumors: toward -omics-based personalized healthcare?
    J Clin Endocrinol Metab. 2008;93:1097-104.
    PubMed     Related articles    Abstract available


    February 2008
  7. NIKIFOROVA MN , Tseng GC, Steward D, Diorio D, et al
    MicroRNA Expression Profiling of Thyroid Tumors: Biological Significance and Diagnostic Utility.
    J Clin Endocrinol Metab. 2008;.
    PubMed     Related articles    Abstract available   Free Full Text


    January 2008
  8. DURAND S , Ferraro-Peyret C, Selmi-Ruby S, Paulin C, et al
    Evaluation of gene expression profiles in thyroid nodule biopsy material to diagnose thyroid cancer.
    J Clin Endocrinol Metab. 2008;.
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  9. KRAUSE K , Eszlinger M, Gimm O, Karger S, et al
    TFF3 based candidate gene discrimination of benign and malignant thyroid tumours in a region with borderline iodine deficiency.
    J Clin Endocrinol Metab. 2008;.
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    December 2007
  10. HAYMART MR , Repplinger DJ, Leverson GE, Elson DF, et al
    Higher Serum TSH Level in Thyroid Nodule Patients is Associated with Greater Risks of Differentiated Thyroid Cancer and Advanced Tumor Stage.
    J Clin Endocrinol Metab. 2007;.
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  11. ELISEI R , Cosci B, Romei C, Bottici V, et al
    Prognostic significance of somatic RET oncogene mutations in sporadic medullary thyroid cancer: A 10 years follow up study.
    J Clin Endocrinol Metab. 2007;.
    PubMed     Related articles    Abstract available   Free Full Text


  12. ROBINSON-WHITE AJ , Hsiao HP, Leitner WW, Greene E, et al
    PKA-Independent Inhibition of Proliferation and Induction of Apoptosis in Human Thyroid Cancer Cells by 8-Cl-Adenosine.
    J Clin Endocrinol Metab. 2007;.
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  13. LIMA J , Feijao T, Ferreira da Silva A, Pereira-Castro I, et al
    High frequency of germline succinate dehydrogenase mutations in sporadic cervical paragangliomas in northern Spain: mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations.
    J Clin Endocrinol Metab. 2007;92:4853-64.
    PubMed     Related articles    Abstract available


    November 2007
  14. BROWN AP , Chen J, Hitchcock YJ, Szabo A, et al
    The Risk of Second Primary Malignancies Up to Three Decades after the Treatment of Differentiated Thyroid Cancer.
    J Clin Endocrinol Metab. 2007;.
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  15. LATROFA F , Ricci D, Grasso L, Vitti P, et al
    Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin autoantibodies.
    J Clin Endocrinol Metab. 2007;.
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  16. ABUBAKER J , Jehan Z, Bavi P, Sultana M, et al
    Clinicopathological analysis of papillary thyroid cancer with PIK3CA alterations in a Middle Eastern population.
    J Clin Endocrinol Metab. 2007;.
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  17. SANTARPIA L , El-Naggar AK, Cote GJ, Myers JN, et al
    PI3K/Akt and Ras/Raf-MAPK pathway mutations in anaplastic thyroid cancer.
    J Clin Endocrinol Metab. 2007;.
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    October 2007
  18. CASTAGNA MG , Brilli L, Pilli T, Montanaro A, et al
    Limited Value of Repeat Recombinant Thyrotropin (rhTSH)-Stimulated Thyroglobulin Testing in Differentiated Thyroid Carcinoma Patients With Previous Negative rhTSH-Stimulated Thyroglobulin and Undetectable Basal Serum Thyroglobulin Levels.
    J Clin Endocrinol Metab. 2007;.
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  19. HOFTIJZER HC , Heemstra KA, Corssmit EP, van der Klaauw AA, et al
    Quality of Life in Cured Patients with Differentiated Thyroid Carcinoma.
    J Clin Endocrinol Metab. 2007;.
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  20. FRAU DV , Lai ML, Caria P, Dettori T, et al
    Trisomy 17 as a Marker For A Subset of Noninvasive Thyroid Nodules With Focal Features of Papillary Carcinoma: Cytogenetic and Molecular Analysis of 62 Cases and Correlation with Histologic Findings.
    J Clin Endocrinol Metab. 2007;.
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  21. MORENO-REYES R , Tang BN, Seret A, Goldman S, et al
    Impaired Iodide Organification in Autonomous Thyroid Nodules.
    J Clin Endocrinol Metab. 2007;.
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  22. LIU D , Liu Z, Jiang D, Dackiw AP, et al
    Inhibitory Effects of the MEK Inhibitor CI-1040 on the Proliferation and Tumor Growth of Thyroid Cancer Cells with BRAF or RAS Mutations.
    J Clin Endocrinol Metab. 2007;.
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  23. JOSEPH B , Ji M, Liu D, Hou P, et al
    Lack of Mutations in the Thyroid Hormone Receptor {alpha} and {beta} Genes, but Frequent Hypermethylation of the Thyroid Hormone Receptor {beta} Gene in Differentiated Thyroid Tumors.
    J Clin Endocrinol Metab. 2007;.
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    September 2007
  24. ELISEI R , Romei C, Cosci B, Agate L, et al
    Ret Genetic Screening in Patients with Medullary Thyroid Cancer and Their Relatives: Experience with 807 Individuals at One Center.
    J Clin Endocrinol Metab. 2007;.
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  25. OUDOUX A , Salaun PY, Bournaud C, Campion L, et al
    Sensitivity and Prognostic Value of Positron Emission Tomography with F-18-Fluorodeoxyglucose and Sensitivity of Immunoscintigraphy in Patients with Medullary Thyroid Carcinoma Treated with Anti-CEA-Targeted Radioimmunotherapy.
    J Clin Endocrinol Metab. 2007;.
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  26. BALL DW , Jin N, Rosen DM, Dackiw A, et al
    Selective Growth Inhibition in BRAF Mutant Thyroid Cancer by the MEK 1/2 Inhibitor AZD6244 (ARRY-142886).
    J Clin Endocrinol Metab. 2007;.
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  27. MITSIADES CS , Hayden P, Kotoula V, McMillin DW, et al
    Bcl-2 Overexpression in Thyroid Carcinoma Cells Increases Sensitivity to Bcl-2 Homology 3 Domain Inhibition.
    J Clin Endocrinol Metab. 2007;.
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  28. LUPI C , Giannini R, Ugolini C, Proietti A, et al
    Association of BRAF V600E Mutation with Poor Clinicopathologic Outcomes in 500 Consecutive Cases of Papillary Thyroid Carcinoma.
    J Clin Endocrinol Metab. 2007;.
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  29. THAM E , Grandell U, Lindgren E, Toss G, et al
    Clinical testing for mutations in the MEN1 gene in Sweden: a report on 200 unrelated cases.
    J Clin Endocrinol Metab. 2007;92:3389-95.
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    August 2007
  30. GIRAUDET AL , Vanel D, Leboulleux S, Auperin A, et al
    Imaging medullary thyroid carcinoma with persistent elevated calcitonin levels.
    J Clin Endocrinol Metab. 2007;.
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  31. SNOZEK CL , Chambers EP, Reading CC, Sebo TJ, et al
    Serum thyroglobulin, high resolution ultrasound and lymph node thyroglobulin in diagnosis of differentiated thyroid carcinoma nodal metastases.
    J Clin Endocrinol Metab. 2007;.
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  32. SEBASTIANES FM , Cerci JJ, Zanoni PH, Soares J Jr, et al
    Role of 18F-FDG PET in Preoperative Assessment of Cytologically Indeterminate Thyroid Nodules.
    J Clin Endocrinol Metab. 2007;.
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  33. GIOVANELLA L , Ceriani L, Crippa S, Mazzucchelli L, et al
    Langherans Cell Histiocytosis of the Thyroid Gland Detected by 18FDG-PET/CT.
    J Clin Endocrinol Metab. 2007;92:2866-7.
    PubMed     Related articles   


  34. ABALOVICH M , Amino N, Barbour LA, Cobin RH, et al
    Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline.
    J Clin Endocrinol Metab. 2007;92.
    PubMed     Related articles    Abstract available


    July 2007
  35. SILVERBERG SJ , Rubin MR, Faiman C, Peacock M, et al
    Cinacalcet Hydrochloride Reduces the Serum Calcium Concentration in Inoperable Parathyroid Carcinoma.
    J Clin Endocrinol Metab. 2007;.
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  36. VOLZKE H , Friedrich N, Schipf S, Haring R, et al
    ASSOCIATION BETWEEN SERUM IGF-1 LEVELS AND THYROID DISORDERS IN A POPULATION-BASED STUDY.
    J Clin Endocrinol Metab. 2007;.
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  37. PILLI T , Brianzoni E, Capoccetti F, Castagna MG, et al
    A comparison of 1850 MBq (50 mCi) and 3700 MBq (100 mCi) 131-iodine administered doses for recombinant TSH-stimulated postoperative thyroid remnant ablation in differentiated thyroid cancer.
    J Clin Endocrinol Metab. 2007;.
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  38. LEBOULLEUX S , Girard E, Rose M, Travagli JP, et al
    Ultrasound criteria of malignancy for cervical lymph nodes in patients followed for differentiated thyroid cancer.
    J Clin Endocrinol Metab. 2007;.
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  39. DURANTE C , Puxeddu E, Ferretti E, Morisi R, et al
    BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism.
    J Clin Endocrinol Metab. 2007;92:2840-3.
    PubMed     Related articles    Abstract available


  40. SMIT JW , Stokkel MP, Pereira AM, Romijn JA, et al
    Bexarotene-induced hypothyroidism: bexarotene stimulates the peripheral metabolism of thyroid hormones.
    J Clin Endocrinol Metab. 2007;92:2496-9.
    PubMed     Related articles    Abstract available


  41. SCHLUMBERGER M , Hitzel A, Toubert ME, Corone C, et al
    Comparison of seven serum thyroglobulin assays in the follow-up of papillary and follicular thyroid cancer patients.
    J Clin Endocrinol Metab. 2007;92:2487-95.
    PubMed     Related articles    Abstract available


  42. HOVENS GC , Stokkel MP, Kievit J, Corssmit EP, et al
    Associations of serum thyrotropin concentrations with recurrence and death in differentiated thyroid cancer.
    J Clin Endocrinol Metab. 2007;92:2610-5.
    PubMed     Related articles    Abstract available


    June 2007
  43. DE GROOT JW , Zonnenberg BA, Quarles van Ufford-Mannesse P, de Vries MM, et al
    A phase-II trial of imatinib therapy for metastatic medullary thyroid carcinoma.
    J Clin Endocrinol Metab. 2007;.
    PubMed     Related articles    Abstract available   Free Full Text


  44. YEUNG SC , She M, Yang H, Pan J, et al
    Combination Chemotherapy including Combretastatin A4 Phosphate and Paclitaxel is Effective against Anaplastic Thyroid Cancer in a Nude Mouse Xenograft Model.
    J Clin Endocrinol Metab. 2007;.
    PubMed     Related articles    Abstract available


  45. ANNAERT M , Thijs M, Sciot R, Decallonne B, et al
    Riedel's Thyroiditis Occurring in a Multinodular Goiter, Mimicking Thyroid Cancer.
    J Clin Endocrinol Metab. 2007;92:2005-6.
    PubMed     Related articles   


  46. WANG Y , Hou P, Yu H, Wang W, et al
    High prevalence and mutual exclusivity of genetic alterations in the phosphatidylinositol-3-kinase/akt pathway in thyroid tumors.
    J Clin Endocrinol Metab. 2007;92:2387-90.
    PubMed     Related articles    Abstract available


  47. BOI F , Maurelli I, Pinna G, Atzeni F, et al
    Calcitonin measurement in wash-out fluid from fine needle aspiration of neck masses in patients with primary and metastatic medullary thyroid carcinoma.
    J Clin Endocrinol Metab. 2007;92:2115-8.
    PubMed     Related articles    Abstract available


  48. LIU D , Liu Z, Condouris S, Xing M, et al
    BRAF V600E maintains proliferation, transformation, and tumorigenicity of BRAF-mutant papillary thyroid cancer cells.
    J Clin Endocrinol Metab. 2007;92:2264-71.
    PubMed     Related articles    Abstract available


    May 2007
  49. GIANNINI R , Ugolini C, Lupi C, Proietti A, et al
    The heterogeneous distribution of BRAF mutation supports the independent clonal origin of distinct tumor foci in multifocal papillary thyroid carcinoma.
    J Clin Endocrinol Metab. 2007;.
    PubMed     Related articles    Abstract available   Free Full Text


  50. RAGO T , Scutari FS, Pinchera A, Vitti P, et al
    Elastography: New developments in ultrasound for predicting malignancy in thyroid nodules.
    J Clin Endocrinol Metab. 2007;.
    PubMed     Related articles    Abstract available


  51. HUANG YY , Yu Z, Lin SF, Li S, et al
    Nectin-1 is a marker of thyroid cancer sensitivity to herpes oncolytic therapy.
    J Clin Endocrinol Metab. 2007;92:1965-70.
    PubMed     Related articles    Abstract available


  52. CONTICELLO C , Adamo L, Giuffrida R, Vicari L, et al
    Proteasome inhibitors synergize with tumor necrosis factor-related apoptosis-induced ligand to induce anaplastic thyroid carcinoma cell death.
    J Clin Endocrinol Metab. 2007;92:1938-42.
    PubMed     Related articles    Abstract available


  53. TAKEUCHI H , Greep NC, Hoon DS, Giuliano AE, et al
    Hypermethylation of adenosine triphosphate-binding cassette transporter genes in primary hyperparathyroidism and its effect on sestamibi imaging.
    J Clin Endocrinol Metab. 2007;92:1785-90.
    PubMed     Related articles    Abstract available


  54. OZAWA A , Agarwal SK, Mateo CM, Burns AL, et al
    The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations.
    J Clin Endocrinol Metab. 2007;92:1948-51.
    PubMed     Related articles    Abstract available


  55. KIM JM , Ryu JS, Kim TY, Kim WB, et al
    18F-fluorodeoxyglucose positron emission tomography does not predict malignancy in thyroid nodules cytologically diagnosed as follicular neoplasm.
    J Clin Endocrinol Metab. 2007;92:1630-4.
    PubMed     Related articles    Abstract available


    April 2007
  56. SIMONDS WF
    Ruling out a suspect: the role of beta-catenin mutation in benign parathyroid neoplasia.
    J Clin Endocrinol Metab. 2007;92:1235-6.
    PubMed     Related articles   


  57. COSTA-GUDA J , Arnold A
    Absence of stabilizing mutations of beta-catenin encoded by CTNNB1 exon 3 in a large series of sporadic parathyroid adenomas.
    J Clin Endocrinol Metab. 2007;92:1564-6.
    PubMed     Related articles    Abstract available


    February 2007
  58. BORGET I , De Pouvourville G, Schlumberger M
    Editorial: Calcitonin determination in patients with nodular thyroid disease.
    J Clin Endocrinol Metab. 2007;92:425-7.
    PubMed     Related articles   


    January 2007
  59. PACIFICO F , Paolillo M, Chiappetta G, Crescenzi E, et al
    RbAp48 IS A TARGET OF NF-{kappa}B ACTIVITY IN THYROID CANCER.
    J Clin Endocrinol Metab. 2007;.
    PubMed     Related articles    Abstract available   Free Full Text


  60. BJORKLUND P , Akerstrom G, Westin G
    Accumulation of nonphosphorylated beta-catenin and c-myc in primary and uremic secondary hyperparathyroid tumors.
    J Clin Endocrinol Metab. 2007;92:338-44.
    PubMed     Related articles    Abstract available


    December 2006
  61. CHIAPPETTA G , Ammirante M, Basile A, Rosati A, et al
    The anti- apoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor- related apoptosis-inducing ligand (TRAIL).
    J Clin Endocrinol Metab. 2006;.
    PubMed     Related articles    Abstract available   Free Full Text


  62. LI W , Venkataraman GM, Ain KB
    Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.
    J Clin Endocrinol Metab. 2006;.
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  63. SAMANDER EH , Arnold A
    Mutational analysis of the vitamin D receptor does not support its candidacy as a tumor suppressor gene in parathyroid adenomas.
    J Clin Endocrinol Metab. 2006;91:5019-21.
    PubMed     Related articles    Abstract available


    November 2006
  64. COSTANTE G , Meringolo D, Durante C, Bianchi D, et al
    PREDICTIVE VALUE OF SERUM CALCITONIN LEVELS FOR PREOPERATIVE DIAGNOSIS OF MEDULLARY THYROID CARCINOMA IN A COHORT OF 5817 CONSECUTIVE PATIENTS WITH THYROID NODULES.
    J Clin Endocrinol Metab. 2006;.
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  65. CHIA SY , Milas M, Reddy SK, Siperstein A, et al
    TSH receptor mRNA measurement in blood as a marker for circulating thyroid cancer cells and its role in the preoperative diagnosis of thyroid cancer.
    J Clin Endocrinol Metab. 2006;.
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  66. ROSS DS
    Predicting thyroid malignancy.
    J Clin Endocrinol Metab. 2006;91:4253-5.
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  67. POLLARD PJ , El-Bahrawy M, Poulsom R, Elia G, et al
    Expression of HIF-1alpha, HIF-2alpha (EPAS1), and their target genes in paraganglioma and pheochromocytoma with VHL and SDH mutations.
    J Clin Endocrinol Metab. 2006;91:4593-8.
    PubMed     Related articles    Abstract available


  68. BROUWERS FM , Eisenhofer G, Tao JJ, Kant JA, et al
    High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing.
    J Clin Endocrinol Metab. 2006;91:4505-9.
    PubMed     Related articles    Abstract available


    October 2006
  69. WADA N , Nakayama H, Suganuma N, Masudo Y, et al
    Prognostic value of the 6th edition AJCC/UICC TNM classification for differentiated thyroid carcinoma with extrathyroid extension.
    J Clin Endocrinol Metab. 2006;.
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  70. SMALLRIDGE RC , Meek SE, Morgan MA, Gates GS, et al
    Monitoring Thyroglobulin in a Sensitive Immunoassay Has Comparable Sensitivity to Recombinant Human TSH Stimulated Thyroglobulin in Follow-Up of Thyroid Cancer Patients.
    J Clin Endocrinol Metab. 2006;.
    PubMed     Related articles    Abstract available   Free Full Text


  71. HACKSHAW A , Harmer C, Mallick U, Haq M, et al
    131I activity for remnant ablation in patients with differentiated thyroid cancer: a systematic review.
    J Clin Endocrinol Metab. 2006;.
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  72. SADETZKI S , Chetrit A, Lubina A, Stovall M, et al
    Risk of Thyroid Cancer Following Childhood Exposure to Ionizing Radiation for Tinea Capitis.
    J Clin Endocrinol Metab. 2006;.
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    September 2006
  73. TRIPONEZ F , Poder L, Zarnegar R, Goldstein R, et al
    Hook needle-guided excision of recurrent differentiated thyroid cancer in previously operated neck compartments: a safe technique for small, non-palpable recurrent disease.
    J Clin Endocrinol Metab. 2006;.
    PubMed     Related articles    Abstract available   Free Full Text


    August 2006
  74. KIM DS , Franklyn JA, Boelaert K, Eggo MC, et al
    Pituitary tumor transforming gene (PTTG) stimulates thyroid cell proliferation via a VEGF/KDR/ID3 autocrine pathway.
    J Clin Endocrinol Metab. 2006;.
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  75. TRONKO MD , Brenner AV, Olijnyk VA, Robbins J, et al
    Autoimmune thyroiditis and exposure to iodine 131 in the Ukrainian cohort study of thyroid cancer and other thyroid diseases following the Chornobyl accident. Results from the first screening cycle (1998-2000).
    J Clin Endocrinol Metab. 2006;.
    PubMed     Related articles    Abstract available   Free Full Text


  76. RODRIGUES M , Li S, Gabriel M, Heute D, et al
    99mTc-Depreotide scintigraphy versus 18F-FDG-PET in the diagnosis of radioiodine-negative thyroid cancer.
    J Clin Endocrinol Metab. 2006;.
    PubMed     Related articles    Abstract available   Free Full Text


    July 2006
  77. BOELAERT K , Horacek J, Holder RL, Watkinson JC, et al
    Serum TSH Concentration as a Novel Predictor of Malignancy in Thyroid Nodules Investigated by Fine Needle Aspiration.
    J Clin Endocrinol Metab. 2006;.
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  78. FRATES MC , Benson CB, Doubilet PM, Kunreuther E, et al
    Prevalence and Distribution of Carcinoma in Patients with Solitary and Multiple Thyroid Nodules on Sonography.
    J Clin Endocrinol Metab. 2006;.
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    June 2006
  79. SUK JO Y , Li S, Hun Song J, Hyun Kwon K, et al
    Influence of the BRAF V600E Mutation on Expression of VEGF in Papillary Thyroid Cancer.
    J Clin Endocrinol Metab. 2006;.
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  80. ZHU Z , Ciampi R, Nikiforova MN, Gandhi M, et al
    PREVALENCE OF RET/PTC REARRANGEMENTS IN THYROID PAPILLARY CARCINOMAS: EFFECTS OF THE DETECTION METHODS AND GENETIC HETEROGENEITY.
    J Clin Endocrinol Metab. 2006;.
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  81. MILLER BS , Gauger PG
    Thyroid Lymphoma Arising from Hashimoto's Thyroiditis.
    J Clin Endocrinol Metab. 2006;.
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