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Articles published in Clin Cancer Res

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    January 2012
  1. GILBERT J , Rudek MA, Higgins MJ, Zhao M, et al
    A Phase I Trial of Erlotinib and Concurrent Chemoradiotherapy (CCR) for Stage III and IV (M0) Squamous Cell Carcinoma of the Head and Neck.
    Clin Cancer Res. 2012.
    PubMed     Text format     Related articles    Abstract available



  2. LEWIS CM , Glisson BS, Feng L, Wan F, et al
    A Phase II Study of Gefitinib for Aggressive Cutaneous Squamous Cell Carcinoma of the Head and Neck.
    Clin Cancer Res. 2012.
    PubMed     Text format     Related articles    Abstract available



  3. YOO DS , Kirkpatrick J, Craciunescu O, Broadwater G, et al
    Prospective Trial of Synchronous Bevacizumab, Erlotinib, and Concurrent Chemoradiation in Locally Advanced Head and Neck Cancer.
    Clin Cancer Res. 2012.
    PubMed     Text format     Related articles    Abstract available



  4. GUBANOVA E , Brown BT, Ivanov SV, Helleday T, et al
    Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival.
    Clin Cancer Res. 2012.
    PubMed     Text format     Related articles    Abstract available



  5. HAYES DN , Lucas AS, Tanvetyanon T, Krzyzanowska MK, et al
    Phase II efficacy and pharmacogenomic study of selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma (IRPTC) with or without follicular elements.
    Clin Cancer Res. 2012.
    PubMed     Text format     Related articles    Abstract available



  6. THARIAT J , Etienne-Grimaldi MC, Grall D, Bensadoun RJ, et al
    Epidermal Growth Factor Receptor protein detection in head and neck cancer patients: a many faceted picture.
    Clin Cancer Res. 2012.
    PubMed     Text format     Related articles    Abstract available



  7. SUN W , Zaboli D, Wang H, Liu Y, et al
    Detection of TIMP3 promoter hypermethylation in salivary rinse as an independent predictor of local recurrence-free survival in head and neck cancer.
    Clin Cancer Res. 2012.
    PubMed     Text format     Related articles    Abstract available



    November 2011
  8. LIM AM , Rischin D, Fisher R, Cao H, et al
    Prognostic significance of plasma osteopontin in patients with loco-regionally advanced head and neck squamous cell carcinoma treated on TROG 02.02 Phase III trial.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  9. SKINNER HD , Sandulache VC, Ow TJ, Meyn RE, et al
    TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  10. BHATTACHARYA A , Roy R, Snijders AM, Hamilton G, et al
    Two Distinct Routes to Oral Cancer Differing in Genome Instability and Risk for Cervical Node Metastasis.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  11. SANO D , Xie TX, Ow TJ, Zhao M, et al
    Disruptive TP53 mutation is associated with aggressive disease characteristics in an orthotopic murine model of oral tongue cancer.
    Clin Cancer Res. 2011;17:6658-70.
    PubMed     Text format     Related articles    Abstract available



    October 2011
  12. HUI A , Bruce JP, Alajez NM, Shi W, et al
    Significance of Dysregulated Metadherin and miR-375 in Head and Neck Cancer.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  13. CHANG KY , Tsai SY, Wu CM, Yen CJ, et al
    Novel PI3K/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  14. SCHACHE AG , Liloglou T, Risk JM, Filia A, et al
    Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination.
    Clin Cancer Res. 2011;17:6262-71.
    PubMed     Text format     Related articles    Abstract available



    September 2011
  15. ANG MK , Patel MR, Yin X, Sundaram S, et al
    High XRCC1-protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



    August 2011
  16. KIM SG , Veena MS, Basak SK, Han E, et al
    Curcumin Treatment Suppresses IKK{beta} Kinase Activity of Salivary Cells of Patients with Head and Neck Cancer: A Pilot Study.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



    July 2011
  17. SADDOUGHI SA , Garrett-Mayer E, Chaudhary U, O'Brien PE, et al
    Results of a Phase II Trial of Gemcitabine plus Doxorubicin in Patients with Recurrent Head and Neck Cancers: Serum C18-ceramide as a Novel Biomarker for Monitoring Response.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  18. WHITE-KONING M , Civade E, Geoerger B, Thomas F, et al
    Population analysis of erlotinib in adults and children reveals pharmacokinetic characteristics as the main factor explaining tolerance particularities in children.
    Clin Cancer Res. 2011;17:4862-71.
    PubMed     Text format     Related articles    Abstract available



  19. ARGIRIS A , Duffy A, Kummar S, Simone NL, et al
    Early tumor progression associated with enhanced EGFR signaling with bortezomib, cetuximab, and radiotherapy for head and neck cancer.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  20. VAEZI A , Wang X, Buch SC, Gooding WE, et al
    XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  21. ISMAIL A , Bandla S, Reveiller M, Toia L, et al
    Early G cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma.
    Clin Cancer Res. 2011;17:4513-22.
    PubMed     Text format     Related articles    Abstract available



  22. SHAO C , Sun W, Tan M, Glazer CA, et al
    Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma.
    Clin Cancer Res. 2011;17:4320-30.
    PubMed     Text format     Related articles    Abstract available



    June 2011
  23. LIM WT , Ng QS, Percy I, Leong SS, et al
    Phase II Study of Pazopanib in Asian Patients with Recurrent/Metastatic Nasopharyngeal Carcinoma.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  24. TYAGI A , Gu M, Takahata T, Frederick BA, et al
    Resveratrol selectively induces DNA damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  25. XU Y , Zhou L, Huang J, Liu F, et al
    Role of Smac in determining the chemotherapeutic response of esophageal squamous cell carcinoma.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  26. MARSHALL ME , Hinz TK, Kono SA, Singleton KR, et al
    Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  27. BHOLA NE , Thomas SM, Freilino ML, Joyce SC, et al
    Targeting GPCR-mediated p70S6K activity may improve head and neck cancer response to cetuximab.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  28. TINHOFER I , Klinghammer K, Weichert W, Knodler M, et al
    Expression of Amphiregulin and EGFRvIII Affect Outcome of Patients with Squamous Cell Carcinoma of the Head and Neck (SCCHN) Receiving Cetuximab-Docetaxel Treatment.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  29. CHIU CC , Lin CY, Lee LY, Chen YJ, et al
    Molecular Chaperones as a Common Set of Proteins That Regulate the Invasion Phenotype of Head and Neck Cancer.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  30. REID BJ , Kostadinov R, Maley CC
    New strategies in Barrett's esophagus: integrating clonal evolutionary theory with clinical management.
    Clin Cancer Res. 2011;17:3512-9.
    PubMed     Text format     Related articles    Abstract available



    May 2011
  31. CALIFANO JA , Carvalho AL, Henrique R, Jeronimo C, et al
    Detection of promoter hypermethylation in salivary rinses as a biomarker for head and neck squamous cell carcinoma surveillance.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  32. XU H , Stabile LP, Gubish CT, Gooding WE, et al
    Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  33. ABRAHAM D , Jackson NE, Gundara JS, Zhao J, et al
    MicroRNA profiling of sporadic and hereditary medullary thyroid cancer identifies predictors of nodal metastasis, prognosis and potential therapeutic targets.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  34. LIN D , Zhang Y, Pan Q, Yang H, et al
    PLK1 is transcriptionally activated by NF-{kappa}B during cell detachment and enhances anoikis resistance through inhibiting {beta}-catenin degradation in esophageal cancer.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  35. ZHENG C , Cotrim AP, Rowzee A, Swaim W, et al
    Prevention of radiation-induced salivary hypofunction following hKGF gene delivery to murine submandibular glands.
    Clin Cancer Res. 2011;17:2842-51.
    PubMed     Text format     Related articles    Abstract available



    April 2011
  36. POAGE GM , Houseman EA, Christensen BC, Butler R, et al
    Global Hypomethylation Identifies Loci Targeted for Hypermethylation in Head and Neck Cancer.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  37. WEN YF , Qi B, Liu H, Mo HY, et al
    Polymorphisms in the Endothelin-1 and Endothelin A Receptor Genes and Survival in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  38. LINDENBERGH-VAN DER PLAS M , Brakenhoff RH, Kuik D, Buijze M, et al
    Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  39. YU KJ , Hsu WL, Pfeiffer RM, Chiang CJ, et al
    Prognostic utility of anti-EBV antibody testing for defining NPC risk among individuals from high-risk NPC families.
    Clin Cancer Res. 2011;17:1906-14.
    PubMed     Text format     Related articles    Abstract available



  40. MOELLER BJ , Yordy JS, Williams MD, Giri U, et al
    DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy.
    Clin Cancer Res. 2011;17:2035-43.
    PubMed     Text format     Related articles    Abstract available



    March 2011
  41. WU MH , Hong HC, Hong TM, Chiang WF, et al
    Targeting galectin-1 in carcinoma-associated fibroblasts inhibits oral squamous cell carcinoma metastasis by downregulating MCP-1/CCL2 expression.
    Clin Cancer Res. 2011;17:1306-16.
    PubMed     Text format     Related articles    Abstract available



  42. CHENG S , Serra S, Mercado M, Ezzat S, et al
    A High-Throughput Proteomic Approach Provides Distinct Signatures for Thyroid Cancer Behavior.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  43. SU H , Hu N, Yang HH, Wang C, et al
    Global gene expression profiling and validation in esophageal squamous cell carcinoma (ESCC) and its association with clinical phenotypes.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



    February 2011
  44. FERRIS RL , Xi L, Seethala RR, Chan J, et al
    Intraoperative qRT-PCR for Detection of Lymph Node Metastasis in Head and Neck Cancer.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  45. PECTASIDES E , Rampias T, Kountourakis P, Sasaki CT, et al
    Comparative Prognostic Value of EGFR Protein Expression Compared with FISH for Head and Neck Squamous Cell Carcinoma (HNSCC).
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  46. SANO D , Matsumoto F, Valdecanas D, Zhao M, et al
    Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  47. BROUTIN S , Ameur N, Lacroix L, Robert T, et al
    Identification of soluble candidate biomarkers of therapeutic response to sunitinib in Medullary Thyroid Carcinoma in preclinical models.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  48. SAEKI H , Kitao H, Yoshinaga K, Nakanoko T, et al
    Copy-neutral Loss of Heterozygosity at the p53 Locus in Carcinogenesis of Esophageal Squamous Cell Carcinomas Associated with p53 Mutations.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  49. MENDEZ E , Lohavanichbutr P, Fan W, Houck J, et al
    Can a Metastatic Gene Expression Profile Outperform Tumor Size as a Predictor of Occult Lymph Node Metastasis in Oral Cancer Patients?
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



    January 2011
  50. HAMANO R , Miyata H, Yamasaki M, Kurokawa Y, et al
    Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  51. SUN Q , Zheng X, Zhang L, Yu J, et al
    Smac Modulates Chemosensitivity in Head and Neck Cancer Cells through the Mitochondrial Apoptotic Pathway.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



  52. KUNST HP , Rutten MH, de Monnink JP, Hoefsloot LH, et al
    SDHAF2 (PGL2-SDH5) and hereditary head and neck paraganglioma.
    Clin Cancer Res. 2011;17:247-54.
    PubMed     Text format     Related articles    Abstract available



  53. GULE MK , Chen Y, Sano D, Frederick MJ, et al
    Targeted Therapy of VEGFR2 and EGFR Significantly Inhibits Growth of Anaplastic Thyroid Cancer in an Orthotopic Murine Model.
    Clin Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available



    December 2010
  54. PHAY JE , Shah MH
    Targeting RET receptor tyrosine kinase activation in cancer.
    Clin Cancer Res. 2010;16:5936-41.
    PubMed     Text format     Related articles    Abstract available



  55. NGUYEN GH , Schetter AJ, Chou DB, Bowman ED, et al
    Inflammatory and microRNA gene expression as prognostic classifier of Barrett's-associated esophageal adenocarcinoma.
    Clin Cancer Res. 2010;16:5824-34.
    PubMed     Text format     Related articles    Abstract available



    November 2010
  56. CRESCENZI M , Persano L, Esposito G, Zulato E, et al
    VANDETANIB IMPROVES ANTI-TUMOR EFFECTS OF L19mTNF{alpha} IN XENOGRAFT MODELS OF ESOPHAGEAL CANCER.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



  57. BANIBRATA S , Peng SH, Saigal B, Williams MD, et al
    Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



  58. GUAN XY , Qin Y, Tang H, Xie F, et al
    Characterization of Tumor-suppressive Function of SOX6 in Human Esophageal Squamous Cell Carcinoma.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



  59. BAUMANN M , Krause M
    CD44: a cancer stem cell-related biomarker with predictive potential for radiotherapy.
    Clin Cancer Res. 2010;16:5091-3.
    PubMed     Text format     Related articles    Abstract available



    October 2010
  60. LIU Z , Liu DX, Bojdani E, El-Naggar AK, et al
    IQGAP1 Plays an Important Role in the Invasiveness of Thyroid Cancer.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



  61. ROBERTS JC , Li G, Reitzel LR, Wei Q, et al
    No evidence of sex-related survival disparities among head and neck cancer patients receiving similar multidisciplinary care: a matched-pair analysis.
    Clin Cancer Res. 2010;16:5019-27.
    PubMed     Text format     Related articles    Abstract available



  62. ZHU GQ , Tang YL, Li L, Zheng M, et al
    Hypoxia inducible factor 1alpha and hypoxia inducible factor 2alpha play distinct and functionally overlapping roles in oral squamous cell carcinoma.
    Clin Cancer Res. 2010;16:4732-41.
    PubMed     Text format     Related articles    Abstract available



  63. MITANI Y , Li J, Rao PH, Zhao YJ, et al
    Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: Incidence, variability, and clinicopathologic significance.
    Clin Cancer Res. 2010;16:4722-31.
    PubMed     Text format     Related articles    Abstract available



    September 2010
  64. CARR LL , Mankoff D, Goulart BH, Eaton KD, et al
    Phase II Study of Sunitinib in FDG-PET Positive, Differentiated Thyroid Cancer and Metastatic Medullary Carcinoma of Thyroid with Functional Imaging Correlation.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



  65. DE JONG MC , Pramana J, van der Wal JE, Lacko M, et al
    CD44 Expression Predicts Local Recurrence After Radiotherapy In Larynx Cancer.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



  66. HSU DS , Lan HY, Huang CH, Tai SK, et al
    Regulation of Excision Repair Cross-Complementation Group 1 by Snail Contributes to Cisplatin Resistance in Head and Neck Cancer.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



    August 2010
  67. CERECER-GIL NY , Figuera LE, Llamas FJ, Lara M, et al
    Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma.
    Clin Cancer Res. 2010;16:4148-54.
    PubMed     Text format     Related articles    Abstract available



  68. HARRINGTON KJ , Hingorani M, Tanay MA, Hickey J, et al
    Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck.
    Clin Cancer Res. 2010;16:4005-15.
    PubMed     Text format     Related articles    Abstract available



    July 2010
  69. VERGEZ S , Delord JP, Thomas F, Rochaix P, et al
    Preclinical and clinical evidence that 18FDG-PET/CT is a reliable tool for the detection of early molecular responses to erlotinib in head and neck cancer.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available



  70. KRUSER TJ , Wheeler DL, Armstrong EA, Iida M, et al
    Augmentation of radiation response by motesanib, a multikinase inhibitor that targets vascular endothelial growth factor receptors.
    Clin Cancer Res. 2010;16:3639-47.
    PubMed     Text format     Related articles    Abstract available



    May 2010
  71. LEEMAN-NEILL RJ , Cai Q, Joyce SC, Thomas SM, et al
    Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.
    Clin Cancer Res. 2010;16:2571-9.
    PubMed     Text format     Related articles    Abstract available



    April 2010
  72. WILLIAMS MD , Roberts DB, Kies MS, Mao L, et al
    Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance.
    Clin Cancer Res. 2010;16:2266-74.
    PubMed     Text format     Related articles    Abstract available



  73. SILVERS AL , Lin L, Bass AJ, Chen G, et al
    Decreased selenium-binding protein 1 in esophageal adenocarcinoma results from posttranscriptional and epigenetic regulation and affects chemosensitivity.
    Clin Cancer Res. 2010;16:2009-21.
    PubMed     Text format     Related articles    Abstract available



  74. NICHOLS AC , Finkelstein DM, Faquin WC, Westra WH, et al
    Bcl2 and human papilloma virus 16 as predictors of outcome following concurrent chemoradiation for advanced oropharyngeal cancer.
    Clin Cancer Res. 2010;16:2138-46.
    PubMed     Text format     Related articles    Abstract available



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