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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Head and Neck Cancer

Free Subscription Articles published in Clin Cancer Res Retrieve available abstracts of 122 articles: HTML format

Single Articles

July 2008
1. NOZAWA H , Howell G, Suzuki S, Zhang Q, et al
   Combined Inhibition of PLC{gamma}-1 and c-Src Abrogates Epidermal Growth Factor Receptor-Mediated Head and Neck Squamous Cell Carcinoma Invasion.
   Clin Cancer Res. 2008;14:4336-4344.
   PubMed     Related articles    Abstract available
   
   
   
2. KOPPIKAR P , Choi SH, Egloff AM, Cai Q, et al
   Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma.
   Clin Cancer Res. 2008;14:4284-4291.
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3. KIM MK , Cho KJ, Kwon GY, Park SI, et al
   Patients with ERCC1-Negative Locally Advanced Esophageal Cancers May Benefit from Preoperative Chemoradiotherapy.
   Clin Cancer Res. 2008;14:4225-4231.
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4. ALLEN C , Saigal K, Nottingham L, Arun P, et al
   Bortezomib-Induced Apoptosis with Limited Clinical Response Is Accompanied by Inhibition of Canonical but not Alternative Nuclear Factor-{kappa}B Subunits in Head and Neck Cancer.
   Clin Cancer Res. 2008;14:4175-85.
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5. CHAN KC , Leung SF, Yeung SW, Chan AT, et al
   Persistent Aberrations in Circulating DNA Integrity after Radiotherapy Are Associated with Poor Prognosis in Nasopharyngeal Carcinoma Patients.
   Clin Cancer Res. 2008;14:4141-4145.
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6. CHIOU SH , Yu CC, Huang CY, Lin SC, et al
   Positive correlations of oct-4 and nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma.
   Clin Cancer Res. 2008;14:4085-95.
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   June 2008
7. WANG SX , Bao A, Herrera SJ, Phillips WT, et al
   Intraoperative 186Re-Liposome Radionuclide Therapy in a Head and Neck Squamous Cell Carcinoma Xenograft Positive Surgical Margin Model.
   Clin Cancer Res. 2008;14:3975-83.
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8. CHEN LC , Hsueh C, Tsang NM, Liang Y, et al
   Heterogeneous ribonucleoprotein k and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma.
   Clin Cancer Res. 2008;14:3807-13.
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9. BERGMANN C , Strauss L, Wang Y, Szczepanski MJ, et al
   T regulatory type 1 cells in squamous cell carcinoma of the head and neck: mechanisms of suppression and expansion in advanced disease.
   Clin Cancer Res. 2008;14:3706-15.
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10. ARAKI K , Ahmad SM, Li G, Bray DA Jr, et al
    Retinoblastoma RB94 Enhances Radiation Treatment of Head and Neck Squamous Cell Carcinoma.
    Clin Cancer Res. 2008;14:3514-9.
    PubMed     Related articles    Abstract available
    
    
    May 2008
11. ZHANG X , Komaki R, Wang L, Fang B, et al
    Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus.
    Clin Cancer Res. 2008;14:2813-23.
    PubMed     Related articles    Abstract available
    
    
    April 2008
12. PAVLOVA I , Williams M, El-Naggar A, Richards-Kortum R, et al
    Understanding the biological basis of autofluorescence imaging for oral cancer detection: high-resolution fluorescence microscopy in viable tissue.
    Clin Cancer Res. 2008;14:2396-404.
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13. MARSIT CJ , Black CC, Posner MR, Kelsey KT, et al
    A genotype-phenotype examination of cyclin d1 on risk and outcome of squamous cell carcinoma of the head and neck.
    Clin Cancer Res. 2008;14:2371-7.
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14. SHUMWAY BS , Kresty LA, Larsen PE, Zwick JC, et al
    Effects of a topically applied bioadhesive berry gel on loss of heterozygosity indices in premalignant oral lesions.
    Clin Cancer Res. 2008;14:2421-30.
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15. PAPADIMITRAKOPOULOU VA , William WN Jr, Dannenberg AJ, Lippman SM, et al
    Pilot randomized phase II study of celecoxib in oral premalignant lesions.
    Clin Cancer Res. 2008;14:2095-101.
    PubMed     Related articles    Abstract available
    
    
    March 2008
16. GU X , Song X, Dong Y, Cai H, et al
    Vitamin E Succinate Induces Ceramide-Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma In vitro and In vivo.
    Clin Cancer Res. 2008;14:1840-8.
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17. LEHNERDT GF , Franz P, Zaqoul A, Schmitz KJ, et al
    Overall and relapse-free survival in oropharyngeal and hypopharyngeal squamous cell carcinoma are associated with genotypes of T393C polymorphism of the GNAS1 gene.
    Clin Cancer Res. 2008;14:1753-8.
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18. SEETHALA RR , Gooding WE, Handler PN, Collins B, et al
    Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes.
    Clin Cancer Res. 2008;14:1303-9.
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19. OH SH , Jin Q, Kim ES, Khuri FR, et al
    Insulin-like growth factor-I receptor signaling pathway induces resistance to the apoptotic activities of SCH66336 (lonafarnib) through Akt/mammalian target of rapamycin-mediated increases in survivin expression.
    Clin Cancer Res. 2008;14:1581-9.
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20. LIN SF , Gao SP, Price DL, Li S, et al
    Synergy of a Herpes Oncolytic Virus and Paclitaxel for Anaplastic Thyroid Cancer.
    Clin Cancer Res. 2008;14:1519-1528.
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    February 2008
21. PATEL V , Hood BL, Molinolo AA, Lee NH, et al
    Proteomic analysis of laser-captured paraffin-embedded tissues: a molecular portrait of head and neck cancer progression.
    Clin Cancer Res. 2008;14:1002-14.
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22. CHIA MC , Leung A, Krushel T, Alajez NM, et al
    Nuclear factor-Y and Epstein Barr virus in nasopharyngeal cancer.
    Clin Cancer Res. 2008;14:984-94.
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23. TWIGGER K , Vidal L, White CL, De Bono JS, et al
    Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy.
    Clin Cancer Res. 2008;14:912-23.
    PubMed     Related articles    Abstract available
    
    
    January 2008
24. KLOPPER JP , Berenz A, Hays WR, Sharma V, et al
    In vivo and Microarray Analysis of Rexinoid-Responsive Anaplastic Thyroid Carcinoma.
    Clin Cancer Res. 2008;14:589-596.
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25. CHENG AL , Huang WG, Chen ZC, Peng F, et al
    Identification of Novel Nasopharyngeal Carcinoma Biomarkers by Laser Capture Microdissection and Proteomic Analysis.
    Clin Cancer Res. 2008;14:435-445.
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26. WESTRA WH , Taube JM, Poeta ML, Begum S, et al
    Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 Gene Mutations in Squamous Cell Carcinoma of the Head and Neck.
    Clin Cancer Res. 2008;14:366-9.
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27. BOULT J , Roberts K, Brookes MJ, Hughes S, et al
    Overexpression of cellular iron import proteins is associated with malignant progression of esophageal adenocarcinoma.
    Clin Cancer Res. 2008;14:379-87.
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28. CARVALHO AL , Jeronimo C, Kim MM, Henrique R, et al
    Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma.
    Clin Cancer Res. 2008;14:97-107.
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29. SACKETT MK , Bairati I, Meyer F, Jobin E, et al
    Prognostic significance of cyclooxygenase-2 overexpression in glottic cancer.
    Clin Cancer Res. 2008;14:67-73.
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    December 2007
30. MITHANI SK , Smith IM, Zhou S, Gray A, et al
    Mitochondrial resequencing arrays detect tumor-specific mutations in salivary rinses of patients with head and neck cancer.
    Clin Cancer Res. 2007;13:7335-40.
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31. COUCH ME , Ferris RL, Brennan JA, Koch WM, et al
    Alteration of Cellular and Humoral Immunity by Mutant p53 Protein and Processed Mutant Peptide in Head and Neck Cancer.
    Clin Cancer Res. 2007;13:7199-206.
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32. THOMAS F , Rochaix P, Benlyazid A, Sarini J, et al
    Pilot study of neoadjuvant treatment with erlotinib in nonmetastatic head and neck squamous cell carcinoma.
    Clin Cancer Res. 2007;13:7086-92.
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    November 2007
33. KIM MS , Yamashita K, Chae YK, Tokumaru Y, et al
    A Promoter Methylation Pattern in the N-Methyl-D-Aspartate Receptor 2B Gene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma.
    Clin Cancer Res. 2007;13:6658-6665.
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34. BEER AJ , Grosu AL, Carlsen J, Kolk A, et al
    [18F]Galacto-RGD Positron Emission Tomography for Imaging of {alpha}v{beta}3 Expression on the Neovasculature in Patients with Squamous Cell Carcinoma of the Head and Neck.
    Clin Cancer Res. 2007;13:6610-6616.
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35. FRIEDMAN J , Nottingham L, Duggal P, Pernas FG, et al
    Deficient TP53 Expression, Function, and Cisplatin Sensitivity Are Restored by Quinacrine in Head and Neck Cancer.
    Clin Cancer Res. 2007;13:6568-6578.
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36. RICHEY LM , George JR, Couch ME, Kanapkey BK, et al
    Defining Cancer Cachexia in Head and Neck Squamous Cell Carcinoma.
    Clin Cancer Res. 2007;13:6561-6567.
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37. ITEN F , Muller B, Schindler C, Rochlitz C, et al
    Response to [90Yttrium-DOTA]-TOC Treatment is Associated with Long-term Survival Benefit in Metastasized Medullary Thyroid Cancer: A Phase II Clinical Trial.
    Clin Cancer Res. 2007;13:6696-6702.
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38. TSE KP , Tsang NM, Chen KD, Li HP, et al
    MCP-1 Promoter Polymorphism at 2518 Is Associated with Metastasis of Nasopharyngeal Carcinoma after Treatment.
    Clin Cancer Res. 2007;13:6320-6326.
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39. STRAUSS L , Bergmann C, Gooding W, Johnson JT, et al
    The Frequency and Suppressor Function of CD4+CD25highFoxp3+ T Cells in the Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck.
    Clin Cancer Res. 2007;13:6301-6311.
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40. JIN Z , Olaru A, Yang J, Sato F, et al
    Hypermethylation of Tachykinin-1 Is a Potential Biomarker in Human Esophageal Cancer.
    Clin Cancer Res. 2007;13:6293-6300.
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41. GIBCUS JH , Menkema L, Mastik MF, Hermsen MA, et al
    Amplicon mapping and expression profiling identify the Fas-associated death domain gene as a new driver in the 11q13.3 amplicon in laryngeal/pharyngeal cancer.
    Clin Cancer Res. 2007;13:6257-66.
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    October 2007
42. GROSS ND , Boyle JO, Du B, Kekatpure VD, et al
    Inhibition of Jun NH2-Terminal Kinases Suppresses the Growth of Experimental Head and Neck Squamous Cell Carcinoma.
    Clin Cancer Res. 2007;13:5910-5917.
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43. LEE TL , Yang XP, Yan B, Friedman J, et al
    A Novel Nuclear Factor-{kappa}B Gene Signature Is Differentially Expressed in Head and Neck Squamous Cell Carcinomas in Association with TP53 Status.
    Clin Cancer Res. 2007;13:5680-5691.
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44. FERRIS RL , Grandis JR
    NF-{kappa}B Gene Signatures and p53 Mutations in Head and Neck Squamous Cell Carcinoma.
    Clin Cancer Res. 2007;13:5663-4.
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45. FERRY DR , Anderson M, Beddard K, Tomlinson S, et al
    A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: evidence of gene expression, cellular, and clinical response.
    Clin Cancer Res. 2007;13:5869-75.
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    September 2007
46. DVORAK K , Chavarria M, Payne CM, Ramsey L, et al
    Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.
    Clin Cancer Res. 2007;13.
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47. MARTONE T , Gillio-Tos A, De Marco L, Fiano V, et al
    Association between hypermethylated tumor and paired surgical margins in head and neck squamous cell carcinomas.
    Clin Cancer Res. 2007;13:5089-94.
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48. MAEDA G , Chiba T, Kawashiri S, Satoh T, et al
    Epigenetic Inactivation of I{kappa}B Kinase-{alpha} in Oral Carcinomas and Tumor Progression.
    Clin Cancer Res. 2007;13:5041-5047.
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49. HOUALI K , Wang X, Shimizu Y, Djennaoui D, et al
    A New Diagnostic Marker for Secreted Epstein-Barr Virus Encoded LMP1 and BARF1 Oncoproteins in the Serum and Saliva of Patients with Nasopharyngeal Carcinoma.
    Clin Cancer Res. 2007;13:4993-5000.
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50. MOLINOLO AA , Hewitt SM, Amornphimoltham P, Keelawat S, et al
    Dissecting the akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.
    Clin Cancer Res. 2007;13:4964-73.
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51. MARTIN RC , Liu Q, Wo JM, Ray MB, et al
    Chemoprevention of carcinogenic progression to esophageal adenocarcinoma by the manganese superoxide dismutase supplementation.
    Clin Cancer Res. 2007;13:5176-82.
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52. RAUSER S , Weis R, Braselmann H, Feith M, et al
    Significance of HER2 low-level copy gain in Barrett's cancer: implications for fluorescence in situ hybridization testing in tissues.
    Clin Cancer Res. 2007;13:5115-23.
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53. VAN WAES C , Yu M, Nottingham L, Karin M, et al
    Inhibitor-kappaB kinase in tumor promotion and suppression during progression of squamous cell carcinoma.
    Clin Cancer Res. 2007;13:4956-9.
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    August 2007
54. KONDO T , Zhu X, Asa SL, Ezzat S, et al
    The Cancer/Testis Antigen Melanoma-Associated Antigen-A3/A6 Is a Novel Target of Fibroblast Growth Factor Receptor 2-IIIb through Histone H3 Modifications in Thyroid Cancer.
    Clin Cancer Res. 2007;13:4713-20.
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55. VAN DEN BROEK GB , Wreesmann VB, van den Brekel MW, Rasch CR, et al
    Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma.
    Clin Cancer Res. 2007;13:4386-91.
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56. MITHANI SK , Taube JM, Zhou S, Smith IM, et al
    Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer.
    Clin Cancer Res. 2007;13:4331-5.
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57. COHEN EE
    A disturbance in the force mitochondrial mutations in squamous cell carcinoma of the head and neck.
    Clin Cancer Res. 2007;13:4317-9.
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58. GOMEZ-RIVERA F , Santillan-Gomez AA, Younes MN, Kim S, et al
    The Tyrosine Kinase Inhibitor, AZD2171, Inhibits Vascular Endothelial Growth Factor Receptor Signaling and Growth of Anaplastic Thyroid Cancer in an Orthotopic Nude Mouse Model.
    Clin Cancer Res. 2007;13:4519-27.
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59. SHIEH TM , Lin SC, Liu CJ, Chang SS, et al
    Association of expression aberrances and genetic polymorphisms of lysyl oxidase with areca-associated oral tumorigenesis.
    Clin Cancer Res. 2007;13.
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60. STRAUSS L , Bergmann C, Szczepanski M, Gooding W, et al
    A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment.
    Clin Cancer Res. 2007;13.
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    July 2007
61. CHEN K , Hu Z, Wang LE, Zhang W, et al
    Polymorphic TP53BP1 and TP53 Gene Interactions Associated with Risk of Squamous Cell Carcinoma of the Head and Neck.
    Clin Cancer Res. 2007;13:4300-5.
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62. BARNES CJ , Ohshiro K, Rayala SK, El-Naggar AK, et al
    Insulin-like Growth Factor Receptor as a Therapeutic Target in Head and Neck Cancer.
    Clin Cancer Res. 2007;13:4291-9.
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63. KANG SY , Han JH, Lee KJ, Choi JH, et al
    Low Expression of Bax Predicts Poor Prognosis in Patients with Locally Advanced Esophageal Cancer Treated with Definitive Chemoradiotherapy.
    Clin Cancer Res. 2007;13:4146-4153.
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64. NOZOE T , Oyama T, Takenoyama M, Hanagiri T, et al
    Significance of immunohistochemical expression of estrogen receptors alpha and beta in squamous cell carcinoma of the esophagus.
    Clin Cancer Res. 2007;13:4046-50.
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65. LIU T , Ding Y, Xie W, Li Z, et al
    An imageable metastatic treatment model of nasopharyngeal carcinoma.
    Clin Cancer Res. 2007;13:3960-7.
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66. HANDRA-LUCA A , Hernandez J, Mountzios G, Taranchon E, et al
    Excision repair cross complementation group 1 immunohistochemical expression predicts objective response and cancer-specific survival in patients treated by Cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma
    Clin Cancer Res. 2007;13:3855-9.
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    June 2007
67. WANG Y , Spitz MR, Lee JJ, Huang M, et al
    Nucleotide excision repair pathway genes and oral premalignant lesions.
    Clin Cancer Res. 2007;13:3753-8.
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68. BIGBEE WL , Grandis JR, Siegfried JM
    Multiple cytokine and growth factor serum biomarkers predict therapeutic response and survival in advanced-stage head and neck cancer patients.
    Clin Cancer Res. 2007;13:3107-8.
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69. LEE J , Suh C, Huh J, Jun HJ, et al
    Effect of positive bone marrow EBV in situ hybridization in staging and survival of localized extranodal natural killer/T-cell lymphoma, nasal-type.
    Clin Cancer Res. 2007;13:3250-4.
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70. ALLEN C , Duffy S, Teknos T, Islam M, et al
    Nuclear factor-kappaB-related serum factors as longitudinal biomarkers of response and survival in advanced oropharyngeal carcinoma.
    Clin Cancer Res. 2007;13:3182-90.
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71. VEKONY H , Ylstra B, Wilting SM, Meijer GA, et al
    DNA copy number gains at loci of growth factors and their receptors in salivary gland adenoid cystic carcinoma.
    Clin Cancer Res. 2007;13:3133-9.
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    May 2007
72. CHOE MS , Chen Z, Klass CM, Zhang X, et al
    Enhancement of docetaxel-induced cytotoxicity by blocking epidermal growth factor receptor and cyclooxygenase-2 pathways in squamous cell carcinoma of the head and neck.
    Clin Cancer Res. 2007;13:3015-23.
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73. LIU Z , Jiang M, Zhao J, Ju H, et al
    Circulating tumor cells in perioperative esophageal cancer patients: quantitative assay system and potential clinical utility.
    Clin Cancer Res. 2007;13:2992-7.
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74. VACHANI A , Nebozhyn M, Singhal S, Alila L, et al
    A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma.
    Clin Cancer Res. 2007;13:2905-15.
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75. EKEBLAD S , Sundin A, Janson ET, Welin S, et al
    Temozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors.
    Clin Cancer Res. 2007;13:2986-91.
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76. ZHOU G , Zhai Y, Cui Y, Zhang X, et al
    MDM2 promoter SNP309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in Chinese population.
    Clin Cancer Res. 2007;13:2627-33.
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    April 2007
77. FENG FY , Lopez CA, Normolle DP, Varambally S, et al
    Effect of epidermal growth factor receptor inhibitor class in the treatment of head and neck cancer with concurrent radiochemotherapy in vivo.
    Clin Cancer Res. 2007;13:2512-8.
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78. LIU W , Baer MR, Bowman MJ, Pera P, et al
    The tyrosine kinase inhibitor imatinib mesylate enhances the efficacy of photodynamic therapy by inhibiting ABCG2.
    Clin Cancer Res. 2007;13:2463-70.
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    March 2007
79. WOLF JS , Li G, Varadhachary A, Petrak K, et al
    Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo.
    Clin Cancer Res. 2007;13:1601-10.
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80. MA J , Liu L, Tang L, Zong J, et al
    Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma: prognostic value and staging categories.
    Clin Cancer Res. 2007;13:1445-52.
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    February 2007
81. LIU D , Hu S, Hou P, Jiang D, et al
    Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant.
    Clin Cancer Res. 2007;13:1341-9.
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82. TANAKA E , Hashimoto Y, Ito T, Kondo K, et al
    The suppression of aurora-A/STK15/BTAK expression enhances chemosensitivity to docetaxel in human esophageal squamous cell carcinoma.
    Clin Cancer Res. 2007;13:1331-40.
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83. BEGUM S , Gillison ML, Nicol TL, Westra WH, et al
    Detection of human papillomavirus-16 in fine-needle aspirates to determine tumor origin in patients with metastatic squamous cell carcinoma of the head and neck.
    Clin Cancer Res. 2007;13:1186-91.
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84. RIGHINI CA , de Fraipont F, Timsit JF, Faure C, et al
    Tumor-specific methylation in saliva: a promising biomarker for early detection of head and neck cancer recurrence.
    Clin Cancer Res. 2007;13:1179-85.
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85. HOU P , Liu D, Shan Y, Hu S, et al
    Genetic alterations and their relationship in the phosphatidylinositol 3-kinase/Akt pathway in thyroid cancer.
    Clin Cancer Res. 2007;13:1161-70.
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86. LUTHRA MG , Ajani JA, Izzo J, Ensor J, et al
    Decreased expression of gene cluster at chromosome 1q21 defines molecular subgroups of chemoradiotherapy response in esophageal cancers.
    Clin Cancer Res. 2007;13:912-9.
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    January 2007
87. SEIWERT TY , Connell PP, Mauer AM, Hoffman PC, et al
    A phase I study of pemetrexed, Carboplatin, and concurrent radiotherapy in patients with locally advanced or metastatic non-small cell lung or esophageal cancer.
    Clin Cancer Res. 2007;13:515-22.
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88. LIAO WT , Song LB, Zhang HZ, Zhang X, et al
    Centromere protein h is a novel prognostic marker for nasopharyngeal carcinoma progression and overall patient survival.
    Clin Cancer Res. 2007;13:508-14.
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89. LAO-SIRIEIX P , Lovat L, Fitzgerald RC
    Cyclin A immunocytology as a risk stratification tool for Barrett's esophagus surveillance.
    Clin Cancer Res. 2007;13.
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90. LOGES S , Clausen H, Reichelt U, Bubenheim M, et al
    Determination of Microvessel Density by Quantitative Real-time PCR in Esophageal Cancer: Correlation with Histologic Methods, Angiogenic Growth Factor Expression, and Lymph Node Metastasis.
    Clin Cancer Res. 2007;13:76-80.
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    December 2006
91. WILLIAMS MD , Chakravarti N, Kies MS, Maruya S, et al
    Implications of methylation patterns of cancer genes in salivary gland tumors.
    Clin Cancer Res. 2006;12:7353-8.
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92. WU X , Gu J, Dong Q, Huang M, et al
    Joint effect of mutagen sensitivity and insulin-like growth factors in predicting the risk of developing secondary primary tumors and tumor recurrence in patients with head and neck cancer.
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