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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in Br J Cancer

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    June 2008
  1. ANTONIOU AC , Cunningham AP, Peto J, Evans DG, et al
    The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.
    Br J Cancer. 2008;98:2015.
    PubMed     Related articles   


  2. O'BRIEN PM , Davies MJ, Scurry JP, Smith AN, et al
    The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.
    Br J Cancer. 2008;98:1880.
    PubMed     Related articles   


  3. LEUNG EL , Fraser M, Fiscus RR, Tsang BK, et al
    Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement in p53 regulation and cisplatin resistance.
    Br J Cancer. 2008;98:1803-9.
    PubMed     Related articles    Abstract available


  4. WERNLI KJ , Newcomb PA, Hampton JM, Trentham-Dietz A, et al
    Inverse association of NSAID use and ovarian cancer in relation to oral contraceptive use and parity.
    Br J Cancer. 2008;98:1781-3.
    PubMed     Related articles    Abstract available


  5. VASEY PA , Gore M, Wilson R, Rustin G, et al
    A phase Ib trial of docetaxel, carboplatin and erlotinib in ovarian, fallopian tube and primary peritoneal cancers.
    Br J Cancer. 2008;98:1774-80.
    PubMed     Related articles    Abstract available


    May 2008
  6. FERRANDINA G , Petrillo M, Carbone A, Zannoni G, et al
    Prognostic role of topoisomerase-IIalpha in advanced ovarian cancer patients.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  7. ENGELSEN IB , Mannelqvist M, Stefansson IM, Carter SL, et al
    Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma.
    Br J Cancer. 2008;98:1662-9.
    PubMed     Related articles    Abstract available


  8. CALCAGNO AM , Fostel JM, To KK, Salcido CD, et al
    Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.
    Br J Cancer. 2008;98:1515-24.
    PubMed     Related articles    Abstract available   Free Full Text


    April 2008
  9. LIM SL , Smith P, Syed N, Coens C, et al
    Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer.
    Br J Cancer. 2008;98:1452-6.
    PubMed     Related articles    Abstract available


  10. SARGENT A , Bailey A, Almonte M, Turner A, et al
    Prevalence of type-specific HPV infection by age and grade of cervical cytology: data from the ARTISTIC trial.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


    March 2008
  11. O'BRIEN PM , Davies MJ, Scurry JP, Smith AN, et al
    The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.
    Br J Cancer. 2008;98:1085-93.
    PubMed     Related articles    Abstract available


  12. LINDEMANN K , Vatten LJ, Ellstrom-Engh M, Eskild A, et al
    Body mass, diabetes and smoking, and endometrial cancer risk: a follow-up study.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  13. WRIGHT JD , Doan T, McBride R, Jacobson JS, et al
    Variability in chemotherapy delivery for elderly women with advanced stage ovarian cancer and its impact on survival.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  14. CHAN JK , Fuh K, Shin JY, Cheung MK, et al
    The treatment and outcomes of early-stage epithelial ovarian cancer: have we made any progress?
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  15. XUE F , Hilakivi-Clarke LA, Maxwell GL, Hankinson SE, et al
    Longitudinal study on birthweight and the incidence of endometrial cancer.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  16. ANTONIOU AC , Cunningham AP, Peto J, Evans DG, et al
    The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  17. AHMED N , Riley C, Quinn MA
    An immunohistochemical perspective of PPARbeta and one of its putative targets PDK1 in normal ovaries, benign and malignant ovarian tumours.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  18. KONECNY GE , Venkatesan N, Yang G, Dering J, et al
    Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  19. INGEMANN-HANSEN O , Lidang M, Niemann I, Dinesen J, et al
    Screening history of women with cervical cancer: a 6-year study in Aarhus, Denmark.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  20. GOTO T , Takano M, Hirata J, Tsuda H, et al
    The involvement of FOXO1 in cytotoxic stress and drug-resistance induced by paclitaxel in ovarian cancers.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  21. YANG X , Fraser M, Abedini MR, Bai T, et al
    Regulation of apoptosis-inducing factor-mediated, cisplatin-induced apoptosis by Akt.
    Br J Cancer. 2008;98:803-8.
    PubMed     Related articles    Abstract available


  22. HUANG YK , You SL, Yuan CC, Ke YM, et al
    Long-term outcomes of high-risk human papillomavirus infection support a long interval of cervical cancer screening.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  23. FRUSCIO R , Colombo N, Lissoni AA, Garbi A, et al
    A phase II randomised clinical trial comparing cisplatin, paclitaxel and ifosfamide with cisplatin, paclitaxel and epirubicin in newly diagnosed advanced epithelial ovarian cancer: long-term survival analysis.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


    January 2008
  24. PEARCE CL , Wu AH, Gayther SA, Bale AE, et al
    Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the ovarian cancer association consortium pooled analysis.
    Br J Cancer. 2008;98:282-288.
    PubMed     Related articles    Abstract available


  25. ALAM SM , Fujimoto J, Jahan I, Sato E, et al
    Coexpression of EphB4 and ephrinB2 in tumour advancement of ovarian cancers.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  26. AKIL N , Kassab A, Yasmeen A, Darnel AD, et al
    Human breast cancer and sexual activities.
    Br J Cancer. 2008;98:508-9.
    PubMed     Related articles   


  27. SUZUKI R , Rylander-Rudqvist T, Saji S, Bergkvist L, et al
    Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women.
    Br J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  28. BOSCH FX , Castellsague X, de Sanjose S
    HPV and cervical cancer: screening or vaccination?
    Br J Cancer. 2008;98:15-21.
    PubMed     Related articles    Abstract available


  29. VAN DE NIEUWENHOF HP , Massuger LF, de Hullu JA, van Ham MA, et al
    Significant decrease of adenocarcinoma in situ not reflected in cervical adenocarcinoma incidence in the Netherlands 1989-2003.
    Br J Cancer. 2008;98:165-7.
    PubMed     Related articles    Abstract available


    December 2007
  30. THORPE H , Brown SR, Sainsbury JR, Perren TJ, et al
    Timing of breast cancer surgery in relation to menstrual cycle phase: no effect on 3-year prognosis: The ITS Study.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  31. GRANSTROM C , Sundquist J, Hemminki K
    Population attributable fractions for ovarian cancer in Swedish women by morphological type.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  32. KABAT GC , Miller AB, Jain M, Rohan TE, et al
    Dietary iron and haem iron intake and risk of endometrial cancer: a prospective cohort study.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    November 2007
  33. LACEY JV JR , Ioffe OB, Ronnett BM, Rush BB, et al
    Endometrial carcinoma risk among women diagnosed with endometrial hyperplasia: the 34-year experience in a large health plan.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  34. BLECHSCHMIDT K , Sassen S, Schmalfeldt B, Schuster T, et al
    The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  35. KRASNER CN , McMeekin DS, Chan S, Braly PS, et al
    A Phase II study of trabectedin single agent in patients with recurrent ovarian cancer previously treated with platinum-based regimens.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  36. HOFFMEISTER M , Raum E, Winter J, Chang-Claude J, et al
    Hormone replacement therapy, body mass, and the risk of colorectal cancer among postmenopausal women from Germany.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    October 2007
  37. YAMAMOTO E , Ino K, Miyoshi E, Shibata K, et al
    Expression of N-acetylglucosaminyltransferase V in endometrial cancer correlates with poor prognosis.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  38. HENKEN FE , Wilting SM, Overmeer RM, van Rietschoten JG, et al
    Sequential gene promoter methylation during HPV-induced cervical carcinogenesis.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  39. NEDERGAARD BS , Ladekarl M, Thomsen HF, Nyengaard JR, et al
    Low density of CD3+, CD4+ and CD8+ cells is associated with increased risk of relapse in squamous cell cervical cancer.
    Br J Cancer. 2007;97:1135-8.
    PubMed     Related articles    Abstract available


  40. GAKIOPOULOU H , Korkolopoulou P, Levidou G, Thymara I, et al
    Minichromosome maintenance proteins 2 and 5 in non-benign epithelial ovarian tumours: relationship with cell cycle regulators and prognostic implications.
    Br J Cancer. 2007;97:1124-34.
    PubMed     Related articles    Abstract available


  41. STEEVENS J , Schouten LJ, Verhage BA, Goldbohm RA, et al
    Tea and coffee drinking and ovarian cancer risk: results from the Netherlands Cohort Study and a meta-analysis.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  42. RAY-COQUARD I , Paraiso D, Guastalla JP, Leduc B, et al
    Intensified dose of cyclophosphamide with G-CSF support versus standard dose combined with platinum in first-line treatment of advanced ovarian cancer a randomised study from the GINECO group.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  43. KIM JJ , Andres-Beck B, Goldie SJ
    The value of including boys in an HPV vaccination programme: a cost-effectiveness analysis in a low-resource setting.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  44. LUCENTEFORTE E , Bosetti C, Talamini R, Montella M, et al
    Diabetes and endometrial cancer: effect modification by body weight, physical activity and hypertension.
    Br J Cancer. 2007;97:995-998.
    PubMed     Related articles    Abstract available


    September 2007
  45. AMANT F , De Knijf A, Van Calster B, Leunen K, et al
    Clinical study investigating the role of lymphadenectomy, surgical castration and adjuvant hormonal treatment in endometrial stromal sarcoma.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  46. SATOH T , Oki A, Uno K, Sakurai M, et al
    High incidence of silent venous thromboembolism before treatment in ovarian cancer.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  47. OTA T , Takeshima N, Tabata T, Hasumi K, et al
    Treatment of squamous cell carcinoma of the uterine cervix with radiation therapy alone: long-term survival, late complications, and incidence of second cancers.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  48. CHANUDET E , Adam P, Nicholson AG, Wotherspoon AC, et al
    Chlamydiae and Mycoplasma infections in pulmonary MALT lymphoma.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  49. PIETERSE AH , Stiggelbout AM, Baas-Thijssen MC, van de Velde CJ, et al
    Benefit from preoperative radiotherapy in rectal cancer treatment: disease-free patients' and oncologists' preferences.
    Br J Cancer. 2007;97:717-24.
    PubMed     Related articles    Abstract available


  50. WYNNE P , Newton C, Ledermann JA, Olaitan A, et al
    Enhanced repair of DNA interstrand crosslinking in ovarian cancer cells from patients following treatment with platinum-based chemotherapy.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    August 2007
  51. SCHUZ J , Martinussen N, Lightfoot T, Roman E, et al
    Molar pregnancy and childhood cancer: a population-based linkage study from Denmark.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  52. TROISI R , Innes KE, Roberts JM, Hoover RN, et al
    Preeclampsia and maternal breast cancer risk by offspring gender: do elevated androgen concentrations play a role?
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  53. MARLOW LA , Waller J, Wardle J
    Public awareness that HPV is a risk factor for cervical cancer.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    July 2007
  54. CHAN JK , Kapp DS, Cheung MK, Osann K, et al
    The impact of the absolute number and ratio of positive lymph nodes on survival of endometrioid uterine cancer patients.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  55. MINAS V , Rolaki A, Kalantaridou SN, Sidiropoulos J, et al
    Intratumoral CRH modulates immuno-escape of ovarian cancer cells through FasL regulation.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  56. ANDERSEN TT , Georgekutty J, Defreest LA, Amaratunga G, et al
    An alpha-fetoprotein-derived peptide reduces the uterine hyperplasia and increases the antitumour effect of tamoxifen.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  57. MONROE KR , Murphy SP, Kolonel LN, Pike MC, et al
    Prospective study of grapefruit intake and risk of breast cancer in postmenopausal women: the Multiethnic Cohort Study.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  58. ZHOU Y , Pan Y, Zhang S, Shi X, et al
    Increased phosphorylation of p70 S6 kinase is associated with HPV16 infection in cervical cancer and esophageal cancer.
    Br J Cancer. 2007;97:218-22.
    PubMed     Related articles    Abstract available


  59. SODEK KL , Ringuette MJ, Brown TJ
    MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  60. AGUAYO F , Castillo A, Koriyama C, Higashi M, et al
    Human papillomavirus-16 is integrated in lung carcinomas: a study in Chile.
    Br J Cancer. 2007;97:85-91.
    PubMed     Related articles    Abstract available


    June 2007
  61. LIU J , Harada H, Ogura M, Shibata T, et al
    Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts.
    Br J Cancer. 2007;96:1871-8.
    PubMed     Related articles    Abstract available


  62. SATO E , Fujimoto J, Toyoki H, Sakaguchi H, et al
    Expression of IP-10 related to angiogenesis in uterine cervical cancers.
    Br J Cancer. 2007;96:1735-9.
    PubMed     Related articles    Abstract available


  63. ALTIERI A , Hemminki K
    Number of siblings and the risk of solid tumours: a nation-wide study.
    Br J Cancer. 2007;96:1755-9.
    PubMed     Related articles    Abstract available


  64. WILD SH , Bryden JR, Lee RJ, Bishop JL, et al
    Cancer, cardiovascular disease and diabetes mortality among women with a history of endometrial cancer.
    Br J Cancer. 2007;96:1747-9.
    PubMed     Related articles    Abstract available


    May 2007
  65. LUTCHMAN SINGH K , Muttukrishna S, Stein RC, McGarrigle HH, et al
    Predictors of ovarian reserve in young women with breast cancer.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  66. CHAN JK , Urban R, Hu JM, Shin JY, et al
    The potential therapeutic role of lymph node resection in epithelial ovarian cancer: a study of 13 918 patients.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  67. YU J , Roy D, Brockmeyer AD, Dubeau L, et al
    Increased chromosomal stability in cultures of ovarian tumours of low malignant potential compared to cystadenomas.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  68. TOMLINSON VA , Newbery HJ, Bergmann JH, Boyd J, et al
    Expression of eEF1A2 is associated with clear cell histology in ovarian carcinomas: overexpression of the gene is not dependent on modifications at the EEF1A2 locus.
    Br J Cancer. 2007;96:1613-20.
    PubMed     Related articles    Abstract available


  69. PIGNATA S , Scambia G, Pisano C, Breda E, et al
    A multicentre phase II study of carboplatin plus pegylated liposomal doxorubicin as first-line chemotherapy for patients with advanced or recurrent endometrial carcinoma: the END-1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gy
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  70. HERMSEN BB , Olivier RI, Verheijen RH, van Beurden M, et al
    No efficacy of annual gynaecological screening in BRCA1/2 mutation carriers; an observational follow-up study.
    Br J Cancer. 2007;96:1335-42.
    PubMed     Related articles    Abstract available


  71. BRINTON LA , Sakoda LC, Lissowska J, Sherman ME, et al
    Reproductive risk factors for endometrial cancer among Polish women.
    Br J Cancer. 2007;96:1450-6.
    PubMed     Related articles    Abstract available


    April 2007
  72. LASSUS H , Butzow R
    The classification of p53 immunohistochemical staining results and patient outcome in ovarian cancer.
    Br J Cancer. 2007;.
    PubMed     Related articles   


  73. BACKEN AC , Cole CL, Lau SC, Clamp AR, et al
    Heparan sulphate synthetic and editing enzymes in ovarian cancer.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  74. MUKHERJEE G , Muralidhar B, Bafna UD, Laskey RA, et al
    MCM immunocytochemistry as a first line cervical screening test in developing countries: a prospective cohort study in a regional cancer centre in India.
    Br J Cancer. 2007;96:1107-11.
    PubMed     Related articles    Abstract available


    March 2007
  75. ALBREKTSEN G , Heuch I, Thoresen S, Kvale G, et al
    Twin births, sex of children and maternal risk of ovarian cancer: a cohort study in Norway.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  76. BULK S , Berkhof J, Rozendaal L, Daalmeijer NC, et al
    The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  77. STANLEY M
    Prophylactic HPV vaccines: prospects for eliminating ano-genital cancer.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  78. KUMAR SR , Masood R, Spannuth WA, Singh J, et al
    The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  79. SANKARANARAYANAN R , Rajkumar R, Esmy PO, Fayette JM, et al
    Effectiveness, safety and acceptability of 'see and treat' with cryotherapy by nurses in a cervical screening study in India.
    Br J Cancer. 2007;96:738-43.
    PubMed     Related articles    Abstract available


  80. FOSTER C , Watson M, Eeles R, Eccles D, et al
    Predictive genetic testing for BRCA1/2 in a UK clinical cohort: three-year follow-up.
    Br J Cancer. 2007;96:718-24.
    PubMed     Related articles    Abstract available


  81. BULKMANS NW , Berkhof J, Bulk S, Bleeker MC, et al
    High-risk HPV type-specific clearance rates in cervical screening.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    February 2007
  82. CHEN CL , Hsieh FC, Lieblein JC, Brown J, et al
    Stat3 activation in human endometrial and cervical cancers.
    Br J Cancer. 2007;96:591-9.
    PubMed     Related articles    Abstract available


  83. FRENCH KM , Barnabas RV, Lehtinen M, Kontula O, et al
    Strategies for the introduction of human papillomavirus vaccination: modelling the optimum age- and sex-specific pattern of vaccination in Finland.
    Br J Cancer. 2007;96:514-8.
    PubMed     Related articles    Abstract available


  84. SWERDLOW AJ , Jones ME
    Ovarian cancer risk in premenopausal and perimenopausal women treated with Tamoxifen: a case-control study.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available


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