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Genetics

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March 2024
1. PENNISI E
   Massive RNA sequencing effort proposed.
   Science. 2024;383:1398.
   PubMed     Abstract available
   
   
   
2. FUENTES A
   Statements by scientific organizations can, and should, shape society.
   Science. 2024;383:eado7084.
   PubMed     Abstract available
   
   
   February 2024
3. KAISER J
   NIH megastudy analyzes first 250,000 genomes.
   Science. 2024;383:809.
   PubMed     Abstract available
   
   
   
4. TITLE PO, Singhal S, Grundler MC, Costa GC, et al
   The macroevolutionary singularity of snakes.
   Science. 2024;383:918-923.
   PubMed     Abstract available
   
   
   
5. DUNCAN RG, Krishnamoorthy R, Harms U, Haskel-Ittah M, et al
   The sociopolitical in human genetics education.
   Science. 2024;383:826-828.
   PubMed     Abstract available
   
   
   
6. DONOVAN BM, Weindling M, Amemiya J, Salazar B, et al
   Humane genomics education can reduce racism.
   Science. 2024;383:818-822.
   PubMed     Abstract available
   
   
   January 2024
7. CERVIA-HASLER C, Bruningk SC, Hoch T, Fan B, et al
   Persistent complement dysregulation with signs of thromboinflammation in active Long Covid.
   Science. 2024;383:eadg7942.
   PubMed     Abstract available
   
   
   
8. NG MSF, Kwok I, Tan L, Shi C, et al
   Deterministic reprogramming of neutrophils within tumors.
   Science. 2024;383:eadf6493.
   PubMed     Abstract available
   
   
   December 2023
9. FILIZOLA M, Javitch JA
   Deciphering downstream receptor signaling.
   Science. 2023;382:1357-1358.
   PubMed     Abstract available
   
   
   
10. LAU SCY, Wilson NG, Golledge NR, Naish TR, et al
    Genomic evidence for West Antarctic Ice Sheet collapse during the Last Interglacial.
    Science. 2023;382:1384-1389.
    PubMed     Abstract available
    
    
    
11. TINSMAN JC, Gruppi C, Bossu CM, Prigge TL, et al
    Genomic analyses reveal poaching hotspots and illegal trade in pangolins from Africa to Asia.
    Science. 2023;382:1282-1286.
    PubMed     Abstract available
    
    
    
12. LIN AT, Hammond-Kaarremaa L, Liu HL, Stantis C, et al
    The history of Coast Salish "woolly dogs" revealed by ancient genomics and Indigenous Knowledge.
    Science. 2023;382:1303-1308.
    PubMed     Abstract available
    
    
    
13. CORUZZI GM, Birnbaum KD
    Philip N. Benfey (1953-2023).
    Science. 2023;382:1127.
    PubMed     Abstract available
    
    
    November 2023
14. LIU Y, Liu S, Tomar A, Yen FS, et al
    Autoregulatory control of mitochondrial glutathione homeostasis.
    Science. 2023;382:820-828.
    PubMed     Abstract available
    
    
    
15. SKINNIDER MA
    From single cells to neural circuits.
    Science. 2023;382:528.
    PubMed     Abstract available
    
    
    October 2023
16. BURBANO HA, Gutaker RM
    Ancient DNA genomics and the renaissance of herbaria.
    Science. 2023;382:59-63.
    PubMed     Abstract available
    
    
    
17. DALEN L, Heintzman PD, Kapp JD, Shapiro B, et al
    Deep-time paleogenomics and the limits of DNA survival.
    Science. 2023;382:48-53.
    PubMed     Abstract available
    
    
    September 2023
18. ENBODY ED, Sendell-Price AT, Sprehn CG, Rubin CJ, et al
    Community-wide genome sequencing reveals 30 years of Darwin's finch evolution.
    Science. 2023;381:eadf6218.
    PubMed     Abstract available
    
    
    
19. SATYAKI PRV
    An epigenetic clock in plants.
    Science. 2023;381:1416.
    PubMed     Abstract available
    
    
    
20. TOPOL EJ
    As artificial intelligence goes multimodal, medical applications multiply.
    Science. 2023;381:adk6139.
    PubMed     Abstract available
    
    
    
21. AGUZZI A, Kampmann M
    Neurodegeneration enters the era of functional genomics.
    Science. 2023;381:eadk5693.
    PubMed     Abstract available
    
    
    
22. SWEASY JB, Hanawalt PC
    Evelyn M. Witkin (1921-2023).
    Science. 2023;381:1052.
    PubMed     Abstract available
    
    
    
23. HU W, Hao Z, Du P, Di Vincenzo F, et al
    Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition.
    Science. 2023;381:979-984.
    PubMed     Abstract available
    
    
    August 2023
24. BRESSAN D, Battistoni G, Hannon GJ
    The dawn of spatial omics.
    Science. 2023;381:eabq4964.
    PubMed     Abstract available
    
    
    
25. JACKSON FLC
    Community-initiated genomics.
    Science. 2023;381:482-483.
    PubMed     Abstract available
    
    
    July 2023
26. TSUI JL, McCrone JT, Lambert B, Bajaj S, et al
    Genomic assessment of invasion dynamics of SARS-CoV-2 Omicron BA.1.
    Science. 2023;381:336-343.
    PubMed     Abstract available
    
    
    June 2023
27. STRAUSFELD NJ, Hou X, Sayre ME, Hirth F, et al
    Response to Comment on "The lower Cambrian lobopodian Cardiodictyon resolves the origin of euarthropod brains".
    Science. 2023;380:eadg6051.
    PubMed     Abstract available
    
    
    
28. SHAO Y, Zhou L, Li F, Zhao L, et al
    Phylogenomic analyses provide insights into primate evolution.
    Science. 2023;380:913-924.
    PubMed     Abstract available
    
    
    
29. RIVAS-GONZALEZ I, Rousselle M, Li F, Zhou L, et al
    Pervasive incomplete lineage sorting illuminates speciation and selection in primates.
    Science. 2023;380:eabn4409.
    PubMed     Abstract available
    
    
    
30. WU H, Wang Z, Zhang Y, Frantz L, et al
    Hybrid origin of a primate, the gray snub-nosed monkey.
    Science. 2023;380:eabl4997.
    PubMed     Abstract available
    
    
    May 2023
31. ANDERSON-TROCME L, Nelson D, Zabad S, Diaz-Papkovich A, et al
    On the genes, genealogies, and geographies of Quebec.
    Science. 2023;380:849-855.
    PubMed     Abstract available
    
    
    
32. VOGEL G
    Human genomic 'bycatch' threatens privacy.
    Science. 2023;380:676-677.
    PubMed     Abstract available
    
    
    
33. MORRIS JA, Caragine C, Daniloski Z, Domingo J, et al
    Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
    Science. 2023;380:eadh7699.
    PubMed     Abstract available
    
    
    
34. LLAMAS B, Roca-Rada X
    Paleogenomic study of the Mexican past.
    Science. 2023;380:578-579.
    PubMed     Abstract available
    
    
    April 2023
35. SULLIVAN PF, Meadows JRS, Gazal S, Phan BN, et al
    Leveraging base-pair mammalian constraint to understand genetic variation and human disease.
    Science. 2023;380:eabn2937.
    PubMed     Abstract available
    
    
    
36. KEOUGH KC, Whalen S, Inoue F, Przytycki PF, et al
    Three-dimensional genome rewiring in loci with human accelerated regions.
    Science. 2023;380:eabm1696.
    PubMed     Abstract available
    
    
    
37. KIRILENKO BM, Munegowda C, Osipova E, Jebb D, et al
    Integrating gene annotation with orthology inference at scale.
    Science. 2023;380:eabn3107.
    PubMed     Abstract available
    
    
    
38. UPHAM NS, Landis MJ
    Genomics expands the mammalverse.
    Science. 2023;380:358-359.
    PubMed     Abstract available
    
    
    
39. XUE JR, Mackay-Smith A, Mouri K, Garcia MF, et al
    The functional and evolutionary impacts of human-specific deletions in conserved elements.
    Science. 2023;380:eabn2253.
    PubMed     Abstract available
    
    
    
40. MOON KL, Huson HJ, Morrill K, Wang MS, et al
    ​Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs.
    Science. 2023;380:eabn5887.
    PubMed     Abstract available
    
    
    
41. FOLEY NM, Mason VC, Harris AJ, Bredemeyer KR, et al
    A genomic timescale for placental mammal evolution.
    Science. 2023;380:eabl8189.
    PubMed     Abstract available
    
    
    
42. ZECHA J, Bayer FP, Wiechmann S, Woortman J, et al
    Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.
    Science. 2023;380:93-101.
    PubMed     Abstract available
    
    
    March 2023
43. YU T, Cui H, Li JC, Luo Y, et al
    Enzyme function prediction using contrastive learning.
    Science. 2023;379:1358-1363.
    PubMed     Abstract available
    
    
    February 2023
44. LIN J, Wu Y, Tian G, Yu D, et al
    Menin "reads" H3K79me2 mark in a nucleosomal context.
    Science. 2023;379:717-723.
    PubMed     Abstract available
    
    
    
45. FEINBERG AP, Levchenko A
    Epigenetics as a mediator of plasticity in cancer.
    Science. 2023;379:eaaw3835.
    PubMed     Abstract available
    
    
    December 2022
46. JOHNSTONE SE, Gladyshev VN, Aryee MJ, Bernstein BE, et al
    Epigenetic clocks, aging, and cancer.
    Science. 2022;378:1276-1277.
    PubMed     Abstract available
    
    
    
47. LIU Q, Zhu J, Dulberger CL, Stanley S, et al
    Tuberculosis treatment failure associated with evolution of antibiotic resilience.
    Science. 2022;378:1111-1118.
    PubMed     Abstract available
    
    
    October 2022
48. REED BD, Meyer MJ, Abramzon V, Ad O, et al
    Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device.
    Science. 2022;378:186-192.
    PubMed     Abstract available
    
    
    September 2022
49. DUFRESNES C, Jablonski D
    A genomics revolution in amphibian taxonomy.
    Science. 2022;377:1272.
    PubMed    
    
    
    
50. TEGALLY H, San JE, Cotten M, Moir M, et al
    The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.
    Science. 2022 Sep 15:eabq5358. doi: 10.1126/science.abq5358.
    PubMed     Abstract available
    
    
    
51. TODD ET, Tonasso-Calviere L, Chauvey L, Schiavinato S, et al
    The genomic history and global expansion of domestic donkeys.
    Science. 2022;377:1172-1180.
    PubMed     Abstract available
    
    
    
52. NOBLE S, Burgess SM, Strauss E
    Christine Guthrie (1945-2022).
    Science. 2022;377:1049.
    PubMed     Abstract available
    
    
    August 2022
53. MATHEWS DJH, Ram N
    Genomic research data and the justice system-Response.
    Science. 2022;377:827.
    PubMed    
    
    
    
54. GREENBAUM D, Gerstein M
    Genomic research data and the justice system.
    Science. 2022;377:826-827.
    PubMed    
    
    
    
55. MCSTEEN P, Kellogg EA
    Molecular, cellular, and developmental foundations of grass diversity.
    Science. 2022;377:599-602.
    PubMed     Abstract available
    
    
    
56. VILGALYS TP, Fogel AS, Anderson JA, Mututua RS, et al
    Selection against admixture and gene regulatory divergence in a long-term primate field study.
    Science. 2022;377:635-641.
    PubMed     Abstract available
    
    
    July 2022
57. KEIZER VIP, Grosse-Holz S, Woringer M, Zambon L, et al
    Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics.
    Science. 2022;377:489-495.
    PubMed     Abstract available
    
    
    
58. PEKAR JE, Magee A, Parker E, Moshiri N, et al
    The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2.
    Science. 2022 Jul 26:eabp8337. doi: 10.1126/science.abp8337.
    PubMed     Abstract available
    
    
    
59. BOEHNKE N, Straehla JP, Safford HC, Kocak M, et al
    Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery.
    Science. 2022;377:eabm5551.
    PubMed     Abstract available
    
    
    June 2022
60. MOSALAGANTI S, Obarska-Kosinska A, Siggel M, Taniguchi R, et al
    AI-based structure prediction empowers integrative structural analysis of human nuclear pores.
    Science. 2022;376:eabm9506.
    PubMed     Abstract available
    
    
    
61. ZHENG W, Zhao S, Yin Y, Zhang H, et al
    High-throughput, single-microbe genomics with strain resolution, applied to a human gut microbiome.
    Science. 2022;376:eabm1483.
    PubMed     Abstract available
    
    
    
62. SUO C, Dann E, Goh I, Jardine L, et al
    Mapping the developing human immune system across organs.
    Science. 2022;376:eabo0510.
    PubMed     Abstract available
    
    
    May 2022
63. GRUEBER CE, Sunnucks P
    Using genomics to fight extinction.
    Science. 2022;376:574-575.
    PubMed     Abstract available
    
    
    April 2022
64. MORRILL K, Hekman J, Li X, McClure J, et al
    Ancestry-inclusive dog genomics challenges popular breed stereotypes.
    Science. 2022;376:eabk0639.
    PubMed     Abstract available
    
    
    
65. SUMIDA TS, Hafler DA
    Population genetics meets single-cell sequencing.
    Science. 2022;376:134-135.
    PubMed     Abstract available
    
    
    
66. OIKAWA M, Kobayashi H, Sanbo M, Mizuno N, et al
    Functional primordial germ cell-like cells from pluripotent stem cells in rats.
    Science. 2022;376:176-179.
    PubMed     Abstract available
    
    
    
67. AGANEZOV S, Yan SM, Soto DC, Kirsche M, et al
    A complete reference genome improves analysis of human genetic variation.
    Science. 2022;376:eabl3533.
    PubMed     Abstract available
    
    
    
68. NURK S, Koren S, Rhie A, Rautiainen M, et al
    The complete sequence of a human genome.
    Science. 2022;376:44-53.
    PubMed     Abstract available
    
    
    
69. GERSHMAN A, Sauria MEG, Guitart X, Vollger MR, et al
    Epigenetic patterns in a complete human genome.
    Science. 2022;376:eabj5089.
    PubMed     Abstract available
    
    
    
70. ALTEMOSE N, Logsdon GA, Bzikadze AV, Sidhwani P, et al
    Complete genomic and epigenetic maps of human centromeres.
    Science. 2022;376:eabl4178.
    PubMed     Abstract available
    
    
    March 2022
71. CHO NH, Cheveralls KC, Brunner AD, Kim K, et al
    OpenCell: Endogenous tagging for the cartography of human cellular organization.
    Science. 2022;375:eabi6983.
    PubMed     Abstract available
    
    
    February 2022
72. WOHNS AW, Wong Y, Jeffery B, Akbari A, et al
    A unified genealogy of modern and ancient genomes.
    Science. 2022;375:eabi8264.
    PubMed     Abstract available
    
    
    
73. CAPORALE N, Leemans M, Birgersson L, Germain PL, et al
    From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures.
    Science. 2022;375:eabe8244.
    PubMed     Abstract available
    
    
    
74. KONG Y, Cao L, Deikus G, Fan Y, et al
    Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution.
    Science. 2022;375:515-522.
    PubMed     Abstract available
    
    
    
75. MAKOWSKI C, van der Meer D, Dong W, Wang H, et al
    Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases.
    Science. 2022;375:522-528.
    PubMed     Abstract available
    
    
    January 2022
76. BANSAL M, Morley RJ, Nagaraju SK, Dutta S, et al
    Southeast Asian Dipterocarp origin and diversification driven by Africa-India floristic interchange.
    Science. 2022;375:455-460.
    PubMed     Abstract available
    
    
    
77. MELANI RD, Gerbasi VR, Anderson LC, Sikora JW, et al
    The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells.
    Science. 2022;375:411-418.
    PubMed     Abstract available
    
    
    December 2021
78. BOSKOVIC F, Keyser UF
    Toward single-molecule proteomics.
    Science. 2021;374:1443-1444.
    PubMed     Abstract available
    
    
    
79. SIREN J, Monlong J, Chang X, Novak AM, et al
    Pangenomics enables genotyping of known structural variants in 5202 diverse genomes.
    Science. 2021;374:abg8871.
    PubMed     Abstract available
    
    
    
80. BRINKERHOFF H, Kang ASW, Liu J, Aksimentiev A, et al
    Multiple rereads of single proteins at single-amino acid resolution using nanopores.
    Science. 2021;374:1509-1513.
    PubMed     Abstract available
    
    
    November 2021
81. PIETZNER M, Wheeler E, Carrasco-Zanini J, Cortes A, et al
    Mapping the proteo-genomic convergence of human diseases.
    Science. 2021;374:eabj1541.
    PubMed     Abstract available
    
    
    October 2021
82. WILKINSON E, Giovanetti M, Tegally H, San JE, et al
    A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa.
    Science. 2021;374:423-431.
    PubMed     Abstract available
    
    
    
83. HERAI RH, Szeto RA, Trujillo CA, Muotri AR, et al
    Response to Comment on "Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment".
    Science. 2021;374:eabi9881.
    PubMed     Abstract available
    
    
    
84. DHAR MS, Marwal R, Vs R, Ponnusamy K, et al
    Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India.
    Science. 2021 Oct 14:eabj9932. doi: 10.1126/science.abj9932.
    PubMed     Abstract available
    
    
    
85. KOCHER A, Papac L, Barquera R, Key FM, et al
    Ten millennia of hepatitis B virus evolution.
    Science. 2021;374:182-188.
    PubMed     Abstract available
    
    
    September 2021
86. LIU Y, Mao X, Krause J, Fu Q, et al
    Insights into human history from the first decade of ancient human genomics.
    Science. 2021;373:1479-1484.
    PubMed     Abstract available
    
    
    
87. ZAHN LM
    The human genome.
    Science. 2021;373:1458-1459.
    PubMed     Abstract available
    
    
    
88. LAPPALAINEN T, MacArthur DG
    From variant to function in human disease genetics.
    Science. 2021;373:1464-1468.
    PubMed     Abstract available
    
    
    
89. LIPPHARDT V, Rappold GA, Surdu M
    Protect minorities in genetic research.
    Science. 2021;373:1452.
    PubMed     Abstract available
    
    
    
90. ROOD JE, Regev A
    The legacy of the Human Genome Project.
    Science. 2021;373:1442-1443.
    PubMed     Abstract available
    
    
    July 2021
91. KRAEMER MUG, Hill V, Ruis C, Dellicour S, et al
    Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence.
    Science. 2021 Jul 22. pii: science.abj0113. doi: 10.1126/science.abj0113.
    PubMed     Abstract available
    
    
    June 2021
92. NANDAGOPAL N, Jambhekar A, Lahav G
    Preparing macrophages for the future.
    Science. 2021;372:1263-1264.
    PubMed    
    
    
    May 2021
93. HOENCAMP C, Dudchenko O, Elbatsh AMO, Brahmachari S, et al
    3D genomics across the tree of life reveals condensin II as a determinant of architecture type.
    Science. 2021;372:984-989.
    PubMed     Abstract available
    
    
    
94. VOSS WN, Hou YJ, Johnson NV, Delidakis G, et al
    Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
    Science. 2021 May 4. pii: science.abg5268. doi: 10.1126/science.abg5268.
    PubMed     Abstract available
    
    
    April 2021
95. COLEMAN M
    Diagnosing nutritional stress in the oceans.
    Science. 2021;372:239-240.
    PubMed    
    
    
    
96. USTICK LJ, Larkin AA, Garcia CA, Garcia NS, et al
    Metagenomic analysis reveals global-scale patterns of ocean nutrient limitation.
    Science. 2021;372:287-291.
    PubMed     Abstract available
    
    
    
97. LEVIN D, Raab N, Pinto Y, Rothschild D, et al
    Diversity and functional landscapes in the microbiota of animals in the wild.
    Science. 2021;372.
    PubMed     Abstract available
    
    
    
98. FARIA NR, Mellan TA, Whittaker C, Claro IM, et al
    Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil.
    Science. 2021 Apr 14. pii: science.abh2644. doi: 10.1126/science.abh2644.
    PubMed     Abstract available
    
    
    
99. KRIAUCIONIS S
    Epigenetic nucleotides enhance therapy.
    Science. 2021;372:127-128.
    PubMed    
    
    
    
100. GIBBONS A
     When modern humans met Neanderthals.
     Science. 2021;372:115-116.
     PubMed    
     
     
     
101. JACOBS BF, Currano ED
     The impactful origin of neotropical rainforests.
     Science. 2021;372:28-29.
     PubMed    
     
     
     March 2021
102. ZEPP JA, Morley MP, Loebel C, Kremp MM, et al
     Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus.
     Science. 2021;371.
     PubMed     Abstract available
     
     
     February 2021
103. BUMPUS NN
     For better drugs, diversify clinical trials.
     Science. 2021;371:570-571.
     PubMed    
     
     
     
104. FRASER CM
     A genome to celebrate.
     Science. 2021;371:545.
     PubMed    
     
     
     January 2021
105. MARTIN MA, VanInsberghe D, Koelle K
     Insights from SARS-CoV-2 sequences.
     Science. 2021;371:466-467.
     PubMed    
     
     
     December 2020
106. KASPER DM, Hintzen J, Wu Y, Ghersi JJ, et al
     The N-glycome regulates the endothelial-to-hematopoietic transition.
     Science. 2020;370:1186-1191.
     PubMed     Abstract available
     
     
     November 2020
107. CAO J
     Tracking development at the cellular level.
     Science. 2020;370:924-925.
     PubMed    
     
     
     
108. STOKSTAD E
     Tomorrow's catch.
     Science. 2020;370:902-905.
     PubMed    
     
     
     
109. VAN DER BURG KRL, Lewis JJ, Brack BJ, Fandino RA, et al
     Genomic architecture of a genetically assimilated seasonal color pattern.
     Science. 2020;370:721-725.
     PubMed     Abstract available
     
     
     
110. SHENHAV L, Zeevi D
     Resource conservation manifests in the genetic code.
     Science. 2020;370:683-687.
     PubMed     Abstract available
     
     
     October 2020
111. BERGSTROM A, Frantz L, Schmidt R, Ersmark E, et al
     Origins and genetic legacy of prehistoric dogs.
     Science. 2020;370:557-564.
     PubMed     Abstract available
     
     
     
112. VERDIN E
     Paolo Sassone-Corsi (1956-2020).
     Science. 2020;370:532.
     PubMed    
     
     
     September 2020
113. SWANN JB, Holland SJ, Petersen M, Pietsch TW, et al
     The immunogenetics of sexual parasitism.
     Science. 2020;369:1608-1615.
     PubMed     Abstract available
     
     
     
114. BRISCOE J, Marin O
     Looking at neurodevelopment through a big data lens.
     Science. 2020;369.
     PubMed     Abstract available
     
     

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