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Articles published in Proc Natl Acad Sci U S A

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    February 2010
  1. LI C , Hatta M, Nidom CA, Muramoto Y, et al
    Reassortment between avian H5N1 and human H3N2 influenza viruses creates hybrid viruses with substantial virulence.
    Proc Natl Acad Sci U S A. 2010.
    PubMed     Text format     Related articles    Abstract available


  2. ZHAO C , Hsiang TY, Kuo RL, Krug RM, et al
    ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells.
    Proc Natl Acad Sci U S A. 2010;107:2253-8.
    PubMed     Text format     Related articles    Abstract available


  3. HALE BG , Kerry PS, Jackson D, Precious BL, et al
    Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein.
    Proc Natl Acad Sci U S A. 2010;107:1954-9.
    PubMed     Text format     Related articles    Abstract available


  4. WU JT , Lee CK, Cowling BJ, Yuen KY, et al
    Logistical feasibility and potential benefits of a population-wide passive-immunotherapy program during an influenza pandemic.
    Proc Natl Acad Sci U S A. 2010.
    PubMed     Text format     Related articles    Abstract available


    January 2010
  5. ALTHOUSE BM , Bergstrom TC, Bergstrom CT
    Evolution in health and medicine Sackler colloquium: a public choice framework for controlling transmissible and evolving diseases.
    Proc Natl Acad Sci U S A. 2010;107 Suppl 1:1696-701.
    PubMed     Text format     Related articles    Abstract available


  6. KISO M , Takahashi K, Sakai-Tagawa Y, Shinya K, et al
    T-705 (favipiravir) activity against lethal H5N1 influenza A viruses.
    Proc Natl Acad Sci U S A. 2010;107:882-7.
    PubMed     Text format     Related articles    Abstract available


  7. WALLINGA J , van Boven M, Lipsitch M
    Optimizing infectious disease interventions during an emerging epidemic.
    Proc Natl Acad Sci U S A. 2010;107:923-8.
    PubMed     Text format     Related articles    Abstract available


  8. NUMATA M , Chu HW, Dakhama A, Voelker DR, et al
    Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection.
    Proc Natl Acad Sci U S A. 2010;107:320-5.
    PubMed     Text format     Related articles    Abstract available


    December 2009
  9. GOLDSTEIN E , Dushoff J, Ma J, Plotkin JB, et al
    Reconstructing influenza incidence by deconvolution of daily mortality time series.
    Proc Natl Acad Sci U S A. 2009;106:21825-9.
    PubMed     Text format     Related articles    Abstract available


  10. MEHLE A , Doudna JA
    Adaptive strategies of the influenza virus polymerase for replication in humans.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    November 2009
  11. GREENBAUM JA , Kotturi MF, Kim Y, Oseroff C, et al
    Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    October 2009
  12. OHIGASHI Y , Ma C, Jing X, Balannick V, et al
    An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  13. WANG CC , Chen JR, Tseng YC, Hsu CH, et al
    Glycans on influenza hemagglutinin affect receptor binding and immune response.
    Proc Natl Acad Sci U S A. 2009.
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  14. LIU J , Stevens DJ, Haire LF, Walker PA, et al
    From the Cover: Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957.
    Proc Natl Acad Sci U S A. 2009;106:17175-80.
    PubMed     Text format     Related articles    Abstract available


    September 2009
  15. GAO Q , Palese P
    Rewiring the RNAs of influenza virus to prevent reassortment.
    Proc Natl Acad Sci U S A. 2009;106:15891-6.
    PubMed     Text format     Related articles    Abstract available


    August 2009
  16. CHU C , Lugovtsev V, Golding H, Betenbaugh M, et al
    Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production.
    Proc Natl Acad Sci U S A. 2009.
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  17. JANG H , Boltz D, Sturm-Ramirez K, Shepherd KR, et al
    Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    July 2009
  18. SMITH GJ , Bahl J, Vijaykrishna D, Zhang J, et al
    Dating the emergence of pandemic influenza viruses.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  19. MA C , Polishchuk AL, Ohigashi Y, Stouffer AL, et al
    Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    June 2009
  20. ROHANI P , Breban R, Stallknecht DE, Drake JM, et al
    Environmental transmission of low pathogenicity avian influenza viruses and its implications for pathogen invasion.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    May 2009
  21. NDIFON W , Wingreen NS, Levin SA
    Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  22. GALLI G , Hancock K, Hoschler K, DeVos J, et al
    Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine.
    Proc Natl Acad Sci U S A. 2009;106:7962-7.
    PubMed     Text format     Related articles    Abstract available


    April 2009
  23. ZHU Q , Zarnitsyn VG, Ye L, Wen Z, et al
    Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  24. PIELAK RM , Schnell JR, Chou JJ
    Mechanism of drug inhibition and drug resistance of influenza A M2 channel.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  25. SORRELL EM , Wan H, Araya Y, Song H, et al
    Minimal molecular constraints for respiratory droplet transmission of an avian-human H9N2 influenza A virus.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  26. MINTERN JD , Bedoui S, Davey GM, Moffat JM, et al
    Transience of MHC Class I-restricted antigen presentation after influenza A virus infection.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    March 2009
  27. PAMER EG
    Tipping the balance in favor of protective immunity during influenza virus infection.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles   


  28. GREBE KM , Hickman HD, Irvine KR, Takeda K, et al
    Sympathetic nervous system control of anti-influenza CD8+ T cell responses.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  29. ALDRIDGE JR JR , Moseley CE, Boltz DA, Negovetich NJ, et al
    TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  30. LIPSITCH M , Viboud C
    Influenza seasonality: lifting the fog.
    Proc Natl Acad Sci U S A. 2009;106:3645-6.
    PubMed     Text format     Related articles   


    February 2009
  31. BASKIN CR , Bielefeldt-Ohmann H, Tumpey TM, Sabourin PJ, et al
    Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  32. GUILLONNEAU C , Mintern JD, Hubert FX, Hurt AC, et al
    Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  33. VAN HOEVEN N , Pappas C, Belser JA, Maines TR, et al
    Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  34. SHAMAN J , Kohn M
    Absolute humidity modulates influenza survival, transmission, and seasonality.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    January 2009
  35. MARSOLAIS D , Hahm B, Walsh KB, Edelmann KH, et al
    A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  36. KHURANA E , Peraro MD, Devane R, Vemparala S, et al
    Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


  37. WAHL A , Schafer F, Bardet W, Buchli R, et al
    HLA class I molecules consistently present internal influenza epitopes.
    Proc Natl Acad Sci U S A. 2009.
    PubMed     Text format     Related articles    Abstract available


    December 2008
  38. YEN HL , Aldridge JR, Boon AC, Ilyushina NA, et al
    Changes in H5N1 influenza virus hemagglutinin receptor binding domain affect systemic spread.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles    Abstract available


  39. BUENO SM , Gonzalez PA, Cautivo KM, Mora JE, et al
    Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG.
    Proc Natl Acad Sci U S A. 2008;105:20822-7.
    PubMed     Text format     Related articles    Abstract available


    November 2008
  40. MODIS Y
    How influenza virus is locked out of the cell.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles   


  41. RANKL C , Kienberger F, Wildling L, Wruss J, et al
    Multiple receptors involved in human rhinovirus attachment to live cells.
    Proc Natl Acad Sci U S A. 2008;105:17778-83.
    PubMed     Text format     Related articles    Abstract available


  42. RUSSELL RJ , Kerry PS, Stevens DJ, Steinhauer DA, et al
    Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles    Abstract available


    September 2008
  43. FLOYD DL , Ragains JR, Skehel JJ, Harrison SC, et al
    Single-particle kinetics of influenza virus membrane fusion.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles    Abstract available


  44. GONZALEZ PA , Prado CE, Leiva ED, Carreno LJ, et al
    Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells.
    Proc Natl Acad Sci U S A. 2008;105:14999-5004.
    PubMed     Text format     Related articles    Abstract available


  45. BHOJ VG , Sun Q, Bhoj EJ, Somers C, et al
    MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus.
    Proc Natl Acad Sci U S A. 2008;105:14046-51.
    PubMed     Text format     Related articles    Abstract available


  46. MESSAGE SD , Laza-Stanca V, Mallia P, Parker HL, et al
    Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production.
    Proc Natl Acad Sci U S A. 2008;105:13562-7.
    PubMed     Text format     Related articles    Abstract available


  47. CHEN MW , Cheng TJ, Huang Y, Jan JT, et al
    A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles    Abstract available


    August 2008
  48. DAS K , Ma LC, Xiao R, Radvansky B, et al
    Structural basis for suppression of a host antiviral response by influenza A virus.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles    Abstract available


  49. CHEN C , Zhuang X
    Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles    Abstract available


  50. JING X , Ma C, Ohigashi Y, Oliveira FA, et al
    Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel.
    Proc Natl Acad Sci U S A. 2008;105:10967-72.
    PubMed     Text format     Related articles    Abstract available


    July 2008
  51. NUNO M , Reichert TA, Chowell G, Gumel AB, et al
    Protecting residential care facilities from pandemic influenza.
    Proc Natl Acad Sci U S A. 2008.
    PubMed     Text format     Related articles    Abstract available


    June 2008
  52. ZENG Q , Langereis MA, van Vliet AL, Huizinga EG, et al
    Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution.
    Proc Natl Acad Sci U S A. 2008;.
    PubMed     Text format     Related articles    Abstract available


  53. ZHENG BJ , Chan KW, Lin YP, Zhao GY, et al
    Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus.
    Proc Natl Acad Sci U S A. 2008;.
    PubMed     Text format     Related articles    Abstract available


    May 2008
  54. BELSER JA , Blixt O, Chen LM, Pappas C, et al
    Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility.
    Proc Natl Acad Sci U S A. 2008;105:7558-63.
    PubMed     Text format     Related articles    Abstract available   Free Full Text


    April 2008
  55. KASHYAP AK , Steel J, Oner AF, Dillon MA, et al
    Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies.
    Proc Natl Acad Sci U S A. 2008;.
    PubMed     Text format     Related articles    Abstract available


    March 2008
  56. GILBERT M , Xiao X, Pfeiffer DU, Epprecht M, et al
    Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia.
    Proc Natl Acad Sci U S A. 2008;105:4769-74.
    PubMed     Text format     Related articles    Abstract available   Free Full Text


  57. JACKSON D , Hossain MJ, Hickman D, Perez DR, et al
    A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity.
    Proc Natl Acad Sci U S A. 2008;.
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  58. HALLORAN ME , Ferguson NM, Eubank S, Longini IM Jr, et al
    Modeling targeted layered containment of an influenza pandemic in the United States.
    Proc Natl Acad Sci U S A. 2008;.
    PubMed     Text format     Related articles    Abstract available   Free Full Text


    February 2008
  59. JOO HM , He Y, Sangster MY
    Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia.
    Proc Natl Acad Sci U S A. 2008;.
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  60. PAPPAS C , Aguilar PV, Basler CF, Solorzano A, et al
    Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus.
    Proc Natl Acad Sci U S A. 2008;.
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  61. SRINIVASAN A , Viswanathan K, Raman R, Chandrasekaran A, et al
    Quantitative biochemical rationale for differences in transmissibility of 1918 pandemic influenza A viruses.
    Proc Natl Acad Sci U S A. 2008;.
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    January 2008
  62. CADY SD , Hong M
    Amantadine-induced conformational and dynamical changes of the influenza M2 transmembrane proton channel.
    Proc Natl Acad Sci U S A. 2008;.
    PubMed     Text format     Related articles    Abstract available


  63. DOWELL SF , Bresee JS
    Pandemic lessons from Iceland.
    Proc Natl Acad Sci U S A. 2008;105:1109-10.
    PubMed     Text format     Related articles   


  64. SONG JH , Nguyen HH, Cuburu N, Horimoto T, et al
    Sublingual vaccination with influenza virus protects mice against lethal viral infection.
    Proc Natl Acad Sci U S A. 2008;.
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  65. GOTTFREDSSON M , Halldorsson BV, Jonsson S, Kristjansson M, et al
    Lessons from the past: Familial aggregation analysis of fatal pandemic influenza (Spanish flu) in Iceland in 1918.
    Proc Natl Acad Sci U S A. 2008;.
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