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Epilepsy

Free Subscription Articles published in Brain Retrieve available abstracts of 91 articles: HTML format

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February 2026
1. REYNOLDS EH
   The neurological significance of folate deficiency in women with epilepsy.
   Brain. 2026 Feb 4:awag024. doi: 10.1093.
   PubMed    
   
   
   
2. LIM Y, Akula SK, Myers AK, Chen C, et al
   ARX mutation-associated interneuron defects provide insights into mechanisms underlying developmental epilepsies.
   Brain. 2026 Feb 3:awag036. doi: 10.1093.
   PubMed     Abstract available
   
   
   January 2026
3. ABDULAZIZ AT, Li J, Sander JW, Zhou D, et al
   Reply: The neurological significance of folate deficiency in women with epilepsy.
   Brain. 2026 Jan 30:awag027. doi: 10.1093.
   PubMed    
   
   
   
4. REVELL AY, Jaskir M, Lucas A, Silva AB, et al
   White matter signals reflect information transmission between brain regions during seizures.
   Brain. 2026;149:77-89.
   PubMed     Abstract available
   
   
   December 2025
5. TOGO M, Lyu D, Huang W, Pantis S, et al
   Electrophysiological connections linking medial pulvinar, anterior nuclei of the thalamus and the hippocampus.
   Brain. 2025;148:4315-4324.
   PubMed     Abstract available
   
   
   
6. XIE K, Korzun J, Zhou DJ, Chang E, et al
   Comparative effectiveness of anti-seizure medications in emulated trials using medical informatics.
   Brain. 2025;148:4288-4298.
   PubMed     Abstract available
   
   
   
7. MAKHOUL GS, Doss DJ, Johnson GW, Withers CP, et al
   Collapse of interictal suppressive networks permits seizure spread.
   Brain. 2025;148:4275-4287.
   PubMed     Abstract available
   
   
   November 2025
8. MOYER MB, Ivanova S, Keledijan K, Kreinbrink M, et al
   SUR1-TRPM4 is expressed in human epilepsy and promotes neuron hyperactivity and seizures in rodents.
   Brain. 2025 Nov 15:awaf435. doi: 10.1093.
   PubMed     Abstract available
   
   
   
9. GAUER L, Haast RAM, Azilinon M, El Mendili MM, et al
   Investigating sodium homeostasis of structural brain hubs in focal epilepsy using 7 T MRI.
   Brain. 2025 Nov 5:awaf409. doi: 10.1093.
   PubMed     Abstract available
   
   
   
10. HUGHES NC, Qian H, Doss DJ, Makhoul GS, et al
    Reward circuit local field potential modulations precede risk taking.
    Brain. 2025;148:3958-3972.
    PubMed     Abstract available
    
    
    October 2025
11. YE ZL, Li WB, Fan CX, Wang J, et al
    Reply: USP25 in genetic generalized epilepsy: a gene under scrutiny.
    Brain. 2025 Oct 27:awaf407. doi: 10.1093.
    PubMed    
    
    
    
12. ERFANIAN OMIDVAR M, Murrell JR, Prentice AJ, Helbig I, et al
    USP25 in genetic generalized epilepsy: a gene under scrutiny.
    Brain. 2025 Oct 27:awaf406. doi: 10.1093.
    PubMed    
    
    
    
13. CAI A, Zhang F, Li J, Wang J, et al
    Compound heterozygous mutations in the SSPOP gene lead to epilepsy and developmental disorders.
    Brain. 2025 Oct 13:awaf327. doi: 10.1093.
    PubMed     Abstract available
    
    
    
14. ABDULAZIZ AT, Hao N, O'Brien TJ, Sander JW, et al
    Folate deficiency in women with epilepsy: a scoping review.
    Brain. 2025 Oct 9:awaf298. doi: 10.1093.
    PubMed     Abstract available
    
    
    September 2025
15. DANG YL, Oliver KL, Esnault K, Bahlo M, et al
    Epilepsy concordance in monozygotic twins: the role of common genetic variants.
    Brain. 2025 Sep 25:awaf362. doi: 10.1093.
    PubMed     Abstract available
    
    
    
16. STAWARSKI M, Ulrich D, Reinartz S, Schwenk J, et al
    Normalization of network activity in an epilepsy model with a constitutively active GABBR2 variant.
    Brain. 2025 Sep 25:awaf356. doi: 10.1093.
    PubMed     Abstract available
    
    
    
17. SUNDMAN AK, Jin S, Vadlamudi L, King GF, et al
    The molecular basis of KCNH1-related epileptic encephalopathy and the challenge of developing targeted therapeutics.
    Brain. 2025 Sep 23:awaf353. doi: 10.1093.
    PubMed     Abstract available
    
    
    
18. AITKEN F, Winston JS, O'Muircheartaigh J, Carmichael DW, et al
    The potential of laminar functional MRI in refining the understanding of epilepsy in humans.
    Brain. 2025 Sep 3:awaf320. doi: 10.1093.
    PubMed     Abstract available
    
    
    
19. COCKLE E, Malpas CB, Coleman H, McIlroy A, et al
    Cortical stimulation predicts language decline following SEEG radiofrequency thermocoagulation.
    Brain. 2025;148:3314-3324.
    PubMed     Abstract available
    
    
    August 2025
20. QUIROZ V, Alecu JE, Zubair U, Bernardi K, et al
    Molecular and clinical spectrum of epilepsy-dyskinesia syndromes: a cross-sectional study of 609 patients.
    Brain. 2025 Aug 14:awaf297. doi: 10.1093.
    PubMed     Abstract available
    
    
    
21. NGO A, Liu L, Lariviere S, Kebets V, et al
    Associations between epilepsy-related polygenic risk and brain morphology in childhood.
    Brain. 2025 Aug 14:awaf259. doi: 10.1093.
    PubMed     Abstract available
    
    
    
22. 
    Correction to: Heterozygous variants in USP25 cause genetic generalized epilepsy.
    Brain. 2025 Aug 6:awaf287. doi: 10.1093.
    PubMed    
    
    
    
23. MELI N, Sheran K, Pitsch J, Krabbe S, et al
    Alterations in dopaminergic innervation and receptors in focal cortical dysplasia.
    Brain. 2025;148:2899-2911.
    PubMed     Abstract available
    
    
    July 2025
24. ENGLOT DJ, Jehi L
    ILAE position on early surgery for drug sensitive lesional focal epilepsy.
    Brain. 2025 Jul 18:awaf266. doi: 10.1093.
    PubMed    
    
    
    
25. BENNINGER F, Goldberg I
    Beyond resistance: early surgery for focal epilepsy.
    Brain. 2025 Jul 3:awaf250. doi: 10.1093.
    PubMed    
    
    
    June 2025
26. DANG YL, Esnault K, Fitt G, O'Brien TJ, et al
    Twins with temporal lobe epilepsy: genetic contributions to hippocampal sclerosis and other subtypes.
    Brain. 2025 Jun 18:awaf209. doi: 10.1093.
    PubMed     Abstract available
    
    
    
27. SEN A
    Disentangling epilepsy and dementia: more to do, together.
    Brain. 2025 Jun 10:awaf225. doi: 10.1093.
    PubMed    
    
    
    
28. HIRANO Y, Miyazaki Y, Ishikawa D, Inahashi H, et al
    Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1-ADAM22/23 pathway.
    Brain. 2025 Jun 2:awaf202. doi: 10.1093.
    PubMed     Abstract available
    
    
    May 2025
29. DIMAKOPOULOS V, Gotman J, Klimes P, von Ellenrieder N, et al
    Multicentre analysis of seizure outcome predicted by removal of high-frequency oscillations.
    Brain. 2025;148:1769-1777.
    PubMed     Abstract available
    
    
    April 2025
30. YAM M, Nassir J, Galber D, Quinn S, et al
    A mouse model of GRIN2D developmental and epileptic encephalopathy recapitulates the human disease.
    Brain. 2025 Apr 25:awaf149. doi: 10.1093.
    PubMed     Abstract available
    
    
    
31. TEOH J, Simko J, Camp CR, Liu CJ, et al
    Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy.
    Brain. 2025 Apr 9:awaf125. doi: 10.1093.
    PubMed     Abstract available
    
    
    March 2025
32. CHENG Y, Wang D, Zhang X, Jin G, et al
    Structural network-specific effect of extreme capsule stimulation for drug-resistant focal epilepsy.
    Brain. 2025 Mar 21:awaf097. doi: 10.1093.
    PubMed     Abstract available
    
    
    
33. THIO BJ, Sinha N, Davis KA, Sinha SR, et al
    Stereo-EEG propagating source reconstruction identifies new surgical targets for epilepsy patients.
    Brain. 2025;148:764-775.
    PubMed     Abstract available
    
    
    
34. MITO R, Cole J, Genc S, Jackson G, et al
    Towards precision MRI biomarkers in epilepsy with normative modelling.
    Brain. 2025 Mar 5:awaf090. doi: 10.1093.
    PubMed     Abstract available
    
    
    February 2025
35. 
    Correction to: Threshold of somatic mosaicism leading to brain dysfunction with focal epilepsy.
    Brain. 2025 Feb 11:awaf041. doi: 10.1093.
    PubMed    
    
    
    
36. CHIANG S, Khambhati AN, Tcheng TK, Loftman AP, et al
    State-dependent effects of responsive neurostimulation depend on seizure localization.
    Brain. 2025;148:521-532.
    PubMed     Abstract available
    
    
    January 2025
37. SAINBURG LE, Englot DJ, Morgan VL
    The impact of resective epilepsy surgery on the brain network: evidence from post-surgical imaging.
    Brain. 2025 Jan 24:awaf026. doi: 10.1093.
    PubMed     Abstract available
    
    
    
38. GLEICHGERRCHT E, Kaestner E, Hassanzadeh R, Roth RW, et al
    Redefining diagnostic lesional status in temporal lobe epilepsy with artificial intelligence.
    Brain. 2025 Jan 22:awaf020. doi: 10.1093.
    PubMed     Abstract available
    
    
    
39. TAI XY, Galovic M
    Late-onset epilepsy and neurodegeneration: intersecting mechanisms or separate entities?
    Brain. 2025;148:6-8.
    PubMed    
    
    
    
40. OERLEMANS J, Alejandro RJ, Van Roost D, Boon P, et al
    Unravelling the origin of reward positivity: a human intracranial event-related brain potential study.
    Brain. 2025;148:199-211.
    PubMed     Abstract available
    
    
    
41. BERECKI G, Tao E, Howell KB, Coorg RK, et al
    Nav1.2 channel mutations preventing fast inactivation lead to SCN2A encephalopathy.
    Brain. 2025;148:212-226.
    PubMed     Abstract available
    
    
    
42. TREVELYAN AJ, Marks VS, Graham RT, Denison T, et al
    On brain stimulation in epilepsy.
    Brain. 2025 Jan 2:awae385. doi: 10.1093.
    PubMed     Abstract available
    
    
    December 2024
43. JACKSON HD, Cotler MJ, Saunders GW, Cornelssen CA, et al
    Intracerebral delivery of antiseizure medications by microinvasive neural implants.
    Brain. 2024;147:4147-4156.
    PubMed     Abstract available
    
    
    
44. WILSON W, Tehrani N, Pittman DJ, Dykens P, et al
    Mapping interictal discharges using intracranial EEG-fMRI to predict postsurgical outcomes.
    Brain. 2024;147:4157-4168.
    PubMed     Abstract available
    
    
    October 2024
45. MHANNA A, Bruss J, Griffis JC, Sullivan AW, et al
    Lesion and lesion network localization of dysnomia after epilepsy surgery.
    Brain. 2024 Oct 18:awae322. doi: 10.1093.
    PubMed     Abstract available
    
    
    
46. MAGIELSKI JH, Ruggiero SM, Xian J, Parthasarathy S, et al
    The clinical and genetic spectrum of paediatric speech and language disorders.
    Brain. 2024 Oct 16:awae264. doi: 10.1093.
    PubMed     Abstract available
    
    
    
47. AZEEM A, Abdallah C, von Ellenrieder N, El Kosseifi C, et al
    Explaining slow seizure propagation with white matter tractography.
    Brain. 2024;147:3458-3470.
    PubMed     Abstract available
    
    
    September 2024
48. BOLLING-LADEGAARD E, Dreier JW, Christensen J
    An algorithm for drug-resistant epilepsy in Danish national registers.
    Brain. 2024 Sep 10:awae286. doi: 10.1093.
    PubMed     Abstract available
    
    
    August 2024
49. BERG AT, Thompson CH, Myers LS, Anderson E, et al
    Expanded clinical phenotype spectrum correlates with variant function in SCN2A-related disorders.
    Brain. 2024;147:2761-2774.
    PubMed     Abstract available
    
    
    July 2024
50. LAGARDE S, Bartolomei F
    Sink into the epileptogenic zone: findings from directed SEEG functional connectivity decomposition.
    Brain. 2024 Jul 29:awae256. doi: 10.1093.
    PubMed    
    
    
    
51. CABALO DG, DeKraker J, Royer J, Xie K, et al
    Differential reorganization of episodic and semantic memory systems in epilepsy-related mesiotemporal pathology.
    Brain. 2024 Jul 26:awae197. doi: 10.1093.
    PubMed     Abstract available
    
    
    
52. MINERE M, Mortensen M, Dorovykh V, Warnes G, et al
    Presynaptic hyperexcitability reversed by positive allosteric modulation of a GABABR epilepsy variant.
    Brain. 2024 Jul 19:awae232. doi: 10.1093.
    PubMed     Abstract available
    
    
    
53. DEVULDER A, Vanderlinden G, Van Langenhoven L, Testelmans D, et al
    Epileptic activity on foramen ovale electrodes is associated with sleep and tau pathology in Alzheimer's disease.
    Brain. 2024 Jul 11:awae231. doi: 10.1093.
    PubMed     Abstract available
    
    
    
54. LARIVIERE S, Park BY, Royer J, DeKraker J, et al
    Connectome reorganization associated with temporal lobe pathology and its surgical resection.
    Brain. 2024;147:2483-2495.
    PubMed     Abstract available
    
    
    June 2024
55. KIM J, Park SM, Koh HY, Ko A, et al
    Threshold of somatic mosaicism leading to brain dysfunction with focal epilepsy.
    Brain. 2024 Jun 25:awae190. doi: 10.1093.
    PubMed     Abstract available
    
    
    
56. BALLERINI A, Biagioli N, Carbone C, Chiari A, et al
    Late-onset temporal lobe epilepsy: insights from brain atrophy and Alzheimer's disease biomarkers.
    Brain. 2024 Jun 25:awae207. doi: 10.1093.
    PubMed     Abstract available
    
    
    
57. FAN CX, Liu XR, Mei DQ, Li BM, et al
    Heterozygous variants in USP25 cause genetic generalized epilepsy.
    Brain. 2024 Jun 14:awae191. doi: 10.1093.
    PubMed     Abstract available
    
    
    
58. DOSS DJ, Shless JS, Bick SK, Makhoul GS, et al
    The interictal suppression hypothesis is the dominant differentiator of seizure onset zones in focal epilepsy.
    Brain. 2024 Jun 14:awae189. doi: 10.1093.
    PubMed     Abstract available
    
    
    May 2024
59. SAINBURG LE, Morgan VL
    Investigation of network reorganization after epilepsy surgery is worth the effort.
    Brain. 2024 May 30:awae172. doi: 10.1093.
    PubMed    
    
    
    
60. WEISS SA, Sperling MR, Engel J Jr, Staba R, et al
    To plan efficacious epilepsy surgery.
    Brain. 2024 May 17:awae162. doi: 10.1093.
    PubMed    
    
    
    
61. ROEHRI N, Vulliemoz S, Lagarde S
    The challenge of assessing invasive biomarkers for epilepsy surgery.
    Brain. 2024 May 16:awae164. doi: 10.1093.
    PubMed    
    
    
    
62. SHI W, Eden U, Kramer MA, Chu CJ, et al
    Reply: The challenge of assessing invasive biomarkers for epilepsy surgery and To plan efficacious epilepsy surgery.
    Brain. 2024 May 16:awae165. doi: 10.1093.
    PubMed    
    
    
    April 2024
63. UPADHYA M, Kirmann T, Wilson MA, Simon CM, et al
    Peripherally-derived LGI1-reactive monoclonal antibodies cause epileptic seizures in vivo.
    Brain. 2024 Apr 25:awae129. doi: 10.1093.
    PubMed     Abstract available
    
    
    
64. MBIZVO GK, Bucci T, Lip GYH, Marson AG, et al
    Morbidity and mortality risks associated with valproate withdrawal in young men and women with epilepsy.
    Brain. 2024 Apr 24:awae128. doi: 10.1093.
    PubMed     Abstract available
    
    
    
65. WODEYAR A, Chinappen D, Mylonas D, Baxter B, et al
    Thalamic epileptic spikes disrupt sleep spindles in patients with epileptic encephalopathy.
    Brain. 2024 Apr 23:awae119. doi: 10.1093.
    PubMed     Abstract available
    
    
    
66. ERIKSSON MH, Prentice F, Piper RJ, Wagstyl K, et al
    Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline?
    Brain. 2024 Apr 20:awae121. doi: 10.1093.
    PubMed     Abstract available
    
    
    
67. DI BERARDINO C, Mainardi M, Brusco S, Benvenuto E, et al
    Reply: Spatial and temporal manipulation of the Scn1a gene affect adult brain function.
    Brain. 2024;147:e31-e33.
    PubMed    
    
    
    
68. JANSEN NA, van den Maagdenberg AMJM
    Spatial and temporal manipulation of the Scn1a gene affect adult brain function.
    Brain. 2024;147:e29-e30.
    PubMed    
    
    
    
69. SPARBER P, Sharova M, Davydenko K, Pyankov D, et al
    Deciphering the impact of coding and non-coding SCN1A gene variants on RNA splicing.
    Brain. 2024;147:1278-1293.
    PubMed     Abstract available
    
    
    
70. MACDONALD-LAURS E, Warren AEL, Francis P, Mandelstam SA, et al
    The clinical, imaging, pathological and genetic landscape of bottom-of-sulcus dysplasia.
    Brain. 2024;147:1264-1277.
    PubMed     Abstract available
    
    
    
71. DI BERARDINO C, Mainardi M, Brusco S, Benvenuto E, et al
    Temporal manipulation of the Scn1a gene reveals its essential role in adult brain function.
    Brain. 2024;147:1216-1230.
    PubMed     Abstract available
    
    
    
72. YUAN Y, Lopez-Santiago L, Denomme N, Chen C, et al
    Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model.
    Brain. 2024;147:1231-1246.
    PubMed     Abstract available
    
    
    March 2024
73. SHIMODA Y, Leite M, Graham RT, Marvin JS, et al
    Extracellular glutamate and GABA transients at the transition from interictal spiking to seizures.
    Brain. 2024;147:1011-1024.
    PubMed     Abstract available
    
    
    
74. VERMOYAL JC, Hardy D, Goirand-Lopez L, Vinck A, et al
    Grey matter heterotopia subtypes show specific morpho-electric signatures and network dynamics.
    Brain. 2024;147:996-1010.
    PubMed     Abstract available
    
    
    February 2024
75. SHI W, Shaw D, Walsh KG, Han X, et al
    Spike ripples localize the epileptogenic zone best: an international intracranial study.
    Brain. 2024 Feb 7:awae037. doi: 10.1093.
    PubMed     Abstract available
    
    
    
76. ALMACELLAS BARBANOJ A, Graham RT, Maffei B, Carpenter JC, et al
    Anti-seizure gene therapy for focal cortical dysplasia.
    Brain. 2024;147:542-553.
    PubMed     Abstract available
    
    
    
77. PASCHEN E, Kleis P, Vieira DM, Heining K, et al
    On-demand low-frequency stimulation for seizure control: efficacy and behavioural implications.
    Brain. 2024;147:505-520.
    PubMed     Abstract available
    
    
    January 2024
78. ALMOUSA H, Lewis SA, Bakhtiari S, Nordlie SH, et al
    TRAPPC6B biallelic variants cause a neurodevelopmental disorder with TRAPP II and trafficking disruptions.
    Brain. 2024;147:311-324.
    PubMed     Abstract available
    
    
    
79. LIN SXN, Ahring PK, Keramidas A, Liao VWY, et al
    Correlations of receptor desensitization of gain-of-function GABRB3 variants with clinical severity.
    Brain. 2024;147:224-239.
    PubMed     Abstract available
    
    
    December 2023
80. DREIER JW, Trabjerg BB, Plana-Ripoll O, Skipper N, et al
    Epilepsy in childhood and school performance: a nation-wide cohort study.
    Brain. 2023 Dec 16:awad382. doi: 10.1093.
    PubMed     Abstract available
    
    
    
81. XIAN J, Thalwitzer KM, McKee J, Sullivan KR, et al
    Delineating clinical and developmental outcomes in STXBP1-related disorders.
    Brain. 2023;146:5182-5197.
    PubMed     Abstract available
    
    
    
82. AGOPYAN-MIU AH, Merricks EM, Smith EH, McKhann GM 2nd, et al
    Cell-type specific and multiscale dynamics of human focal seizures in limbic structures.
    Brain. 2023;146:5209-5223.
    PubMed     Abstract available
    
    
    
83. WITHERS CP, Diamond JM, Yang B, Snyder K, et al
    Identifying sources of human interictal discharges with travelling wave and white matter propagation.
    Brain. 2023;146:5168-5181.
    PubMed     Abstract available
    
    
    
84. VAN HUGTE EJH, Lewerissa EI, Wu KM, Scheefhals N, et al
    SCN1A-deficient excitatory neuronal networks display mutation-specific phenotypes.
    Brain. 2023;146:5153-5167.
    PubMed     Abstract available
    
    
    October 2023
85. SURYAVANSHI P, Sawant-Pokam P, Clair S, Brennan KC, et al
    Increased presynaptic excitability in a migraine with aura mutation.
    Brain. 2023 Oct 13:awad326. doi: 10.1093.
    PubMed     Abstract available
    
    
    
86. KAESTNER E, Reyes A
    Out of one, how many? Subtyping in epilepsy.
    Brain. 2023 Oct 12:awad354. doi: 10.1093.
    PubMed    
    
    
    
87. XIAO F, Caciagli L, Wandschneider B, Sone D, et al
    Identification of different MRI atrophy progression trajectories in epilepsy by subtype and stage inference.
    Brain. 2023 Oct 9:awad284. doi: 10.1093.
    PubMed     Abstract available
    
    
    
88. ANDERSON DN, Charlebois CM, Smith EH, Davis TS, et al
    Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes.
    Brain. 2023 Oct 5:awad343. doi: 10.1093.
    PubMed     Abstract available
    
    
    
89. CAMPOS-RODRIGUEZ C, Palmer D, Forcelli PA
    Optogenetic stimulation of the superior colliculus suppresses genetic absence seizures.
    Brain. 2023;146:4320-4335.
    PubMed     Abstract available
    
    
    September 2023
90. MARTINS CUSTODIO H, Clayton LM, Bellampalli R, Pagni S, et al
    Widespread genomic influences on phenotype in Dravet syndrome, a 'monogenic' condition.
    Brain. 2023;146:3885-3897.
    PubMed     Abstract available
    
    
    July 2023
91. MAROOFIAN R, Kaiyrzhanov R, Cali E, Zamani M, et al
    Biallelic MED27 variants lead to variable ponto-cerebello-lental degeneration with movement disorders.
    Brain. 2023 Jul 30:awad257. doi: 10.1093.
    PubMed     Abstract available
    
    

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