: The AMEDEO Literature Guide

Home The Word Brain

My Amedeo

FAQ

Privacy

About

2049 Chinese

The 20K Word Road to Mandarin Proficiency

By B. S. Kamps et al.

Drug Resistance

Free Subscription

Articles published in Antimicrob Agents Chemother
Retrieve available abstracts of 391 articles:
HTML format

Single Articles

April 2024

LOSSOUARN J, Beurrier E, Bouteau A, Moncaut E, et al
The virtue of training: extending phage host spectra against vancomycin-resistant Enterococcus faecium strains using the Appelmans method.
Antimicrob Agents Chemother. 2024 Apr 9:e0143923. doi: 10.1128/aac.01439.
PubMed Abstract available

TENG T, Chen S, Huo F, Jia J, et al
Efflux pump effects on levofloxacin resistance in Mycobacterium abscessus.
Antimicrob Agents Chemother. 2024 Apr 4:e0134823. doi: 10.1128/aac.01348.
PubMed Abstract available

SHANG Y, Zhang Y, Wang R, Peng Y, et al
Deciphering the molecular and functional basis of TMexCD1: the plasmid-encoded efflux pump of resistance-nodulation-division superfamily.
Antimicrob Agents Chemother. 2024;68:e0167823.
PubMed Abstract available

RIBEIRO DOS SANTOS A, Gade L, Misas E, Litvintseva AP, et al
Bimodal distribution of azole susceptibility in Sporothrix brasiliensis isolates in Brazil.
Antimicrob Agents Chemother. 2024;68:e0162023.
PubMed Abstract available

TAIT JR, Anderson D, Nation RL, Creek DJ, et al
Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2024;68:e0108123.
PubMed Abstract available

YANO H, Hayashi W, Kawakami S, Aoki S, et al
Nationwide genome surveillance of carbapenem-resistant Pseudomonas aeruginosa in Japan.
Antimicrob Agents Chemother. 2024 Apr 2:e0166923. doi: 10.1128/aac.01669.
PubMed Abstract available

March 2024

MAIA AR, Cezard A, Fouquenet D, Vasseur V, et al
Preventive nasal administration of flagellin restores antimicrobial effect of gentamicin and protects against a multidrug-resistant strain of Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2024 Mar 25:e0136123. doi: 10.1128/aac.01361.
PubMed Abstract available

SEGAWA T, Masuda K, Hisatsune J, Ishida-Kuroki K, et al
Genomic analysis of inter-hospital transmission of vancomycin-resistant Enterococcus faecium sequence type 80 isolated during an outbreak in Hiroshima, Japan.
Antimicrob Agents Chemother. 2024 Mar 20:e0171623. doi: 10.1128/aac.01716.
PubMed Abstract available

LI W, He Z, Di W, Xu W, et al
Transposition mechanism of ISApl1-the determinant of colistin resistance dissemination.
Antimicrob Agents Chemother. 2024;68:e0123123.
PubMed Abstract available

ANDRE C, Van Camp AG, Ung L, Gilmore MS, et al
Characterization of the resistome and predominant genetic lineages of Gram-positive bacteria causing keratitis.
Antimicrob Agents Chemother. 2024;68:e0124723.
PubMed Abstract available

CARUSO L, Mellini M, Catalano Gonzaga O, Astegno A, et al
Hydrogen sulfide production does not affect antibiotic resistance in Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2024 Mar 6:e0007524. doi: 10.1128/aac.00075.
PubMed Abstract available

February 2024

ZHANG M, Yang B, Shi J, Wang Z, et al
Host defense peptides mitigate the spread of antibiotic resistance in physiologically relevant condition.
Antimicrob Agents Chemother. 2024 Feb 28:e0126123. doi: 10.1128/aac.01261.
PubMed Abstract available

MULATO A, Lansdon E, Aoyama R, Voigt J, et al
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
Antimicrob Agents Chemother. 2024 Feb 21:e0137323. doi: 10.1128/aac.01373.
PubMed Abstract available

FREIBERG JA, Tao L, Manuel C, Mike LA, et al
A multi-species outbreak of VIM-producing carbapenem-resistant bacteria in a burn unit and subsequent investigation of rapid development of cefiderocol resistance.
Antimicrob Agents Chemother. 2024 Feb 20:e0150723. doi: 10.1128/aac.01507.
PubMed Abstract available

BASSERES E, Eubank TA, Begum K, Alam MJ, et al
Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.
Antimicrob Agents Chemother. 2024 Feb 16:e0162123. doi: 10.1128/aac.01621.
PubMed Abstract available

ERSOY SC, Proctor RA, Rose WE, Abdelhady W, et al
Sensitizing methicillin-resistant Staphylococcus aureus (MRSA) to cefuroxime: the synergic effect of bicarbonate and the wall teichoic acid inhibitor ticlopidine.
Antimicrob Agents Chemother. 2024 Feb 13:e0162723. doi: 10.1128/aac.01627.
PubMed Abstract available

PITOUT JDD, Peirano G, Matsumura Y, DeVinney R, et al
Escherichia coli sequence type 410 with carbapenemases: a paradigm shift within E. coli toward multidrug resistance.
Antimicrob Agents Chemother. 2024;68:e0133923.
PubMed Abstract available

DRUSIN SI, Le Terrier C, Poirel L, Bonomo RA, et al
Structural basis of metallo-beta-lactamase resistance to taniborbactam.
Antimicrob Agents Chemother. 2024;68:e0116823.
PubMed Abstract available

January 2024

JIANG X, Li D, Sun Z, Lu Y, et al
Type I BREX system defends against antibiotic-resistant plasmids in Escherichia coli.
Antimicrob Agents Chemother. 2024 Jan 30:e0112823. doi: 10.1128/aac.01128.
PubMed Abstract available

IOVLEVA A, McElheny CL, Fowler EL, Cober E, et al
In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals.
Antimicrob Agents Chemother. 2024 Jan 30:e0125823. doi: 10.1128/aac.01258.
PubMed Abstract available

ZALACAIN M, Achard P, Llanos A, Morrissey I, et al
Meropenem-ANT3310, a unique beta-lactam-beta-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant Acinetobacter baumannii.
Antimicrob Agents Chemother. 2024 Jan 30:e0112023. doi: 10.1128/aac.01120.
PubMed Abstract available

AXELL-HOUSE DB, Simar SR, Panesso D, Rincon S, et al
LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium.
Antimicrob Agents Chemother. 2024 Jan 30:e0106923. doi: 10.1128/aac.01069.
PubMed Abstract available

ALDEJOHANN AM, Menner C, Thielemann N, Martin R, et al
In vitro activity of ibrexafungerp against clinically relevant echinocandin-resistant Candida strains.
Antimicrob Agents Chemother. 2024 Jan 11:e0132423. doi: 10.1128/aac.01324.
PubMed Abstract available

TERAN N, Egge SL, Phe K, Baptista RP, et al
The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy.
Antimicrob Agents Chemother. 2024;68:e0100923.
PubMed Abstract available

CHEN T, Yao J, Quan K, Xu J, et al
Repurposing a human acetyl-CoA carboxylase inhibitor firsocostat to treat fungal candidiasis alone and in combination.
Antimicrob Agents Chemother. 2024;68:e0113123.
PubMed Abstract available

December 2023

TAKEMURA M, Nakamura R, Ota M, Nakai R, et al
In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates.
Antimicrob Agents Chemother. 2023;67:e0034623.
PubMed Abstract available

November 2023

ZHAO J, Pu D, Li Z, Liu X, et al
In vitro activity of cefiderocol, a siderophore cephalosporin, against carbapenem-resistant hypervirulent Klebsiella pneumoniae in China.
Antimicrob Agents Chemother. 2023 Nov 28:e0073523. doi: 10.1128/aac.00735.
PubMed Abstract available

JIAO F, Bao Y, Li M, Zhang Y, et al
Unraveling the mechanism of ceftaroline-induced allosteric regulation in penicillin-binding protein 2a: insights for novel antibiotic development against methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2023 Nov 16:e0089523. doi: 10.1128/aac.00895.
PubMed Abstract available

DIAZ-GARCIA J, Machado M, Alcala L, Reigadas E, et al
Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022.
Antimicrob Agents Chemother. 2023;67:e0098623.
PubMed Abstract available

BOSCH A, Macha ME, Ren Q, Kohler P, et al
Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.
Antimicrob Agents Chemother. 2023;67:e0162522.
PubMed Abstract available

SCHILDKRAUT JA, Raaijmakers J, Aarnoutse R, Hoefsloot W, et al
The role of rifampicin within the treatment of Mycobacterium avium pulmonary disease.
Antimicrob Agents Chemother. 2023;67:e0087423.
PubMed Abstract available

YAMADA T, Maeda M, Nagai H, Salamin K, et al
Two different types of tandem sequences mediate the overexpression of TinCYP51B in azole-resistant Trichophyton indotineae.
Antimicrob Agents Chemother. 2023;67:e0093323.
PubMed Abstract available

October 2023

JIANG S, Chen M, Zhang J, Ba X, et al
Profiling daptomycin resistance among diverse methicillin-resistant Staphylococcus aureus lineages in China.
Antimicrob Agents Chemother. 2023 Oct 30:e0056323. doi: 10.1128/aac.00563.
PubMed Abstract available

ZHANG S-P, Ye Y-P, Hou J, Ye Z-R, et al
Antitoxin MqsA decreases antibiotic susceptibility through the global regulator AgtR in Pseudomonas fluorescens.
Antimicrob Agents Chemother. 2023 Oct 25:e0081223. doi: 10.1128/aac.00812.
PubMed Abstract available

TAKAHASHI H, Morita M, Kamiya H, Fukusumi M, et al
Emergence of ciprofloxacin- and penicillin-resistant Neisseria meningitidis isolates in Japan between 2003 and 2020 and its genetic features.
Antimicrob Agents Chemother. 2023 Oct 24:e0074423. doi: 10.1128/aac.00744.
PubMed Abstract available

LAU JZ, Kuo SH, Belo Y, Malach E, et al
Antibacterial efficacy of an ultra-short palmitoylated random peptide mixture in mouse models of infection by carbapenem-resistant Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2023 Oct 11:e0057423. doi: 10.1128/aac.00574.
PubMed Abstract available

KUHBACHER A, Merschak P, Haas H, Liebl M, et al
The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus.
Antimicrob Agents Chemother. 2023 Oct 10:e0091823. doi: 10.1128/aac.00918.
PubMed Abstract available

LOMOVSKAYA O, Castanheira M, Lindley J, Rubio-Aparicio D, et al
In vitro potency of xeruborbactam in combination with multiple beta-lactam antibiotics in comparison with other beta-lactam/beta-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum beta-lactamase-producing Enterob
Antimicrob Agents Chemother. 2023 Oct 6:e0044023. doi: 10.1128/aac.00440.
PubMed Abstract available

September 2023

MIRON-OCAMPO A, Beattie SR, Guin S, Conway T, et al
CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms.
Antimicrob Agents Chemother. 2023 Sep 13:e0056723. doi: 10.1128/aac.00567.
PubMed Abstract available

PODOLL JD, Rosen E, Wang W, Gao Y, et al
A small-molecule membrane fluidizer re-sensitizes methicillin-resistant Staphylococcus aureus (MRSA) to beta-lactam antibiotics.
Antimicrob Agents Chemother. 2023 Sep 8:e0005123. doi: 10.1128/aac.00051.
PubMed Abstract available

GIULIERI SG
Case Commentary: The hidden side of oxacillin resistance in Staphylococcus aureus.
Antimicrob Agents Chemother. 2023 Sep 1:e0071623. doi: 10.1128/aac.00716.
PubMed Abstract available

August 2023

LOMOVSKAYA O, Tsivkovski R, Totrov M, Dressel D, et al
New boronate drugs and evolving NDM-mediated beta-lactam resistance.
Antimicrob Agents Chemother. 2023 Aug 31:e0057923. doi: 10.1128/aac.00579.
PubMed Abstract available

TAIT JR, Harper M, Cortes-Lara S, Rogers KE, et al
Ceftolozane-Tazobactam against Pseudomonas aeruginosa Cystic Fibrosis Clinical Isolates in the Hollow-Fiber Infection Model: Challenges Imposed by Hypermutability and Heteroresistance.
Antimicrob Agents Chemother. 2023;67:e0041423.
PubMed Abstract available

July 2023

WANG X, Liu T, Lv X, Sun N, et al
A Potential Nontraditional Approach To Combat tmexCD1-toprJ1-Mediated Tigecycline Resistance: Melatonin as a Synergistic Adjuvant of Tigecycline.
Antimicrob Agents Chemother. 2023;67:e0004723.
PubMed Abstract available

SCOTT NE, Edwin Erayil S, Kline SE, Selmecki A, et al
Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy.
Antimicrob Agents Chemother. 2023 Jul 10:e0054323. doi: 10.1128/aac.00543.
PubMed Abstract available

ZHU G, Chen S, Zhang Y, Lu L, et al
Mitochondrial Membrane-Associated Protein Mba1 Confers Antifungal Resistance by Affecting the Production of Reactive Oxygen Species in Aspergillus fumigatus.
Antimicrob Agents Chemother. 2023 Jul 10:e0022523. doi: 10.1128/aac.00225.
PubMed Abstract available

GINGRAS H, Peillard-Fiorente F, Godin C, Patron K, et al
New Resistance Mutations Linked to Decreased Susceptibility to Solithromycin in Streptococcus pneumoniae Revealed by Chemogenomic Screens.
Antimicrob Agents Chemother. 2023 Jul 6:e0039523. doi: 10.1128/aac.00395.
PubMed Abstract available

June 2023

HELFER VE, Dias BB, Lock GA, Tomaszewski CA, et al
Population Pharmacokinetic Modeling of Free Plasma and Free Brain Concentrations of Ceftaroline in Healthy and Methicillin-Resistant Staphylococcus aureus-Infected Wistar Rats.
Antimicrob Agents Chemother. 2023 Jun 27:e0038223. doi: 10.1128/aac.00382.
PubMed Abstract available

ANDRADE ESN, Brandao JG, Silva JSD, Coriolano CRF, et al
Erratum for Andrade et al., "Antimicrobial Resistance among Leprosy Patients in Brazil: Real-World Data Based on the National Surveillance Plan".
Antimicrob Agents Chemother. 2023 Jun 26:e0065823. doi: 10.1128/aac.00658.
PubMed

SATLIN MJ, Simner PJ, Slover CM, Yamano Y, et al
Cefiderocol Treatment for Patients with Multidrug- and Carbapenem-Resistant Pseudomonas aeruginosa Infections in the Compassionate Use Program.
Antimicrob Agents Chemother. 2023 Jun 22:e0019423. doi: 10.1128/aac.00194.
PubMed Abstract available

HESS KA, Kooda K, Shirley JD, Schuetz AN, et al
Failure of mecA/mecC PCR Testing to Accurately Predict Oxacillin Resistance in a Patient with Staphylococcus aureus Infective Endocarditis.
Antimicrob Agents Chemother. 2023 Jun 21:e0043723. doi: 10.1128/aac.00437.
PubMed Abstract available

ASRAT H, Samaroo-Campbell J, Ata S, Quale J, et al
Contribution of Iron-Transport Systems and beta-Lactamases to Cefiderocol Resistance in Clinical Isolates of Acinetobacter baumannii Endemic to New York City.
Antimicrob Agents Chemother. 2023;67:e0023423.
PubMed Abstract available

TAMMA PD, Arias CA, Shields RK
Antimicrobial Agents and Chemotherapy Launches a New Section Focused on Innovative Antimicrobial Stewardship Studies.
Antimicrob Agents Chemother. 2023;67:e0052623.
PubMed Abstract available

BIDAUD AL, Moreno-Sabater A, Normand AC, Cremer G, et al
Evaluation of Gradient Concentration Strips for Detection of Terbinafine Resistance in Trichophyton spp.
Antimicrob Agents Chemother. 2023;67:e0171622.
PubMed Abstract available

HALL CM, Somprasong N, Hagen JP, Nottingham R, et al
Exploring Cefiderocol Resistance Mechanisms in Burkholderia pseudomallei.
Antimicrob Agents Chemother. 2023;67:e0017123.
PubMed Abstract available

TSUI CK, Ben Abid F, Al Ismail K, McElheny CL, et al
Genomic Epidemiology of Carbapenem-Resistant Klebsiella in Qatar: Emergence and Dissemination of Hypervirulent Klebsiella pneumoniae Sequence Type 383 Strains.
Antimicrob Agents Chemother. 2023 Jun 13:e0003023. doi: 10.1128/aac.00030.
PubMed Abstract available

May 2023

NELSON-RIGG R, Fagan SP, Jaremko WJ, Pata JD, et al
Pre-Steady-State Kinetic Characterization of an Antibiotic-Resistant Mutant of Staphylococcus aureus DNA Polymerase PolC.
Antimicrob Agents Chemother. 2023 May 24:e0157122. doi: 10.1128/aac.01571.
PubMed Abstract available

KORDALEWSKA M, Cancino-Prado G, Nobrega de Almeida Junior J, Brasil Brandao I, et al
Novel Non-Hot Spot Modification in Fks1 of Candida auris Confers Echinocandin Resistance.
Antimicrob Agents Chemother. 2023 May 24:e0042323. doi: 10.1128/aac.00423.
PubMed Abstract available

KRAJEWSKA J, Tyski S, Laudy AE
Mutant Prevention Concentration, Frequency of Spontaneous Mutant Selection, and Mutant Selection Window-a New Approach to the In Vitro Determination of the Antimicrobial Potency of Compounds.
Antimicrob Agents Chemother. 2023;67:e0137322.
PubMed Abstract available

SRINIVASAN K, Ho DY
Case Commentary: "Salvage Treatment of Refractory HSV Oral Lesions with Pritelivir in Allogeneic Hematopoietic Cell Transplant Recipients" by Bosetti et al.
Antimicrob Agents Chemother. 2023;67:e0027623.
PubMed

April 2023

SOBEL JD
Resistance to Fluconazole of Candida albicans in Vaginal Isolates: a 10-Year Study in a Clinical Referral Center.
Antimicrob Agents Chemother. 2023 Apr 24:e0018123. doi: 10.1128/aac.00181.
PubMed Abstract available

ELGAMMAL Y, Salama EA, Seleem MN
Atazanavir Resensitizes Candida auris to Azoles.
Antimicrob Agents Chemother. 2023 Apr 24:e0163122. doi: 10.1128/aac.01631.
PubMed Abstract available

WOOD GE, Kim CM, Aguila LKT, Cichewicz RH, et al
In Vitro Susceptibility and Resistance of Mycoplasma genitalium to Nitroimidazoles.
Antimicrob Agents Chemother. 2023;67:e0000623.
PubMed Abstract available

D'ANGELO F, Rocha EPC, Rendueles O
The Capsule Increases Susceptibility to Last-Resort Polymyxins, but Not to Other Antibiotics, in Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2023;67:e0012723.
PubMed Abstract available

XIAO MA, Cleyle J, Yoo S, Forrest M, et al
The G118R plus R263K Combination of Integrase Mutations Associated with Dolutegravir-Based Treatment Failure Reduces HIV-1 Replicative Capacity and Integration.
Antimicrob Agents Chemother. 2023 Apr 18:e0138622. doi: 10.1128/aac.01386.
PubMed Abstract available

TANG B, Yang A, Liu P, Wang Z, et al
Outer Membrane Vesicles Transmitting bla(NDM-1) Mediate the Emergence of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2023 Apr 13:e0144422. doi: 10.1128/aac.01444.
PubMed Abstract available

March 2023

KHATEB A, Gago S, Bromley M, Richardson M, et al
Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus.
Antimicrob Agents Chemother. 2023 Mar 28:e0125322. doi: 10.1128/aac.01253.
PubMed Abstract available

LI D, Ge Y, Wang N, Shi Y, et al
Identification and Characterization of a Novel Major Facilitator Superfamily Efflux Pump, SA09310, Mediating Tetracycline Resistance in Staphylococcus aureus.
Antimicrob Agents Chemother. 2023 Mar 23:e0169622. doi: 10.1128/aac.01696.
PubMed Abstract available

HIRAYAMA T, Miyazaki T, Sumiyoshi M, Ito Y, et al
Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations.
Antimicrob Agents Chemother. 2023 Mar 15:e0124322. doi: 10.1128/aac.01243.
PubMed Abstract available

February 2023

PRESENTE S, Bonnal C, Normand AC, Gaudonnet Y, et al
Hospital Clonal Outbreak of Fluconazole-Resistant Candida parapsilosis Harboring the Y132F ERG11p Substitution in a French Intensive Care Unit.
Antimicrob Agents Chemother. 2023 Feb 28:e0113022. doi: 10.1128/aac.01130.
PubMed Abstract available

LOHSEN S, Stephens DS
Inducible Mega-Mediated Macrolide Resistance Confers Heteroresistance in Streptococcus pneumoniae.
Antimicrob Agents Chemother. 2023 Feb 27:e0131922. doi: 10.1128/aac.01319.
PubMed Abstract available

GARCIA A, Huh EY, Lee SC
Serine/Threonine Phosphatase Calcineurin Orchestrates the Intrinsic Resistance to Micafungin in the Human-Pathogenic Fungus Mucor circinelloides.
Antimicrob Agents Chemother. 2023;67:e0068622.
PubMed Abstract available

SAMERNATE T, Htoo HH, Sugie J, Chavasiri W, et al
High-Resolution Bacterial Cytological Profiling Reveals Intrapopulation Morphological Variations upon Antibiotic Exposure.
Antimicrob Agents Chemother. 2023;67:e0130722.
PubMed Abstract available

LONG J, Zhang J, Xi Y, Zhao J, et al
Genomic Insights into CRISPR-Harboring Plasmids in the Klebsiella Genus: Distribution, Backbone Structures, Antibiotic Resistance, and Virulence Determinant Profiles.
Antimicrob Agents Chemother. 2023 Feb 15:e0118922. doi: 10.1128/aac.01189.
PubMed Abstract available

BONN CM, Rafiqullah IM, Crawford JA, Qian YM, et al
Repeated Emergence of Variant TetR Family Regulator, FarR, and Increased Resistance to Antimicrobial Unsaturated Fatty Acid among Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2023 Feb 6:e0074922. doi: 10.1128/aac.00749.
PubMed Abstract available

January 2023

ZHANG F, Li Z, Liu X, Luo G, et al
Molecular Characteristics of an NDM-4 and OXA-181 Co-Producing K51-ST16 Carbapenem-Resistant Klebsiella pneumoniae: Study of Its Potential Dissemination Mediated by Conjugative Plasmids and Insertion Sequences.
Antimicrob Agents Chemother. 2023 Jan 5:e0135422. doi: 10.1128/aac.01354.
PubMed Abstract available

December 2022

SIMAR SR, Tran TT, Rydell KB, Panesso D, et al
Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida.
Antimicrob Agents Chemother. 2022 Dec 21:e0128422. doi: 10.1128/aac.01284.
PubMed Abstract available

KARLOWSKY JA, Hackel MA, Wise MG, Six DA, et al
In Vitro Activity of Cefepime-Taniborbactam and Comparators against Clinical Isolates of Gram-Negative Bacilli from 2018 to 2020: Results from the Global Evaluation of Antimicrobial Resistance via Surveillance (GEARS) Program.
Antimicrob Agents Chemother. 2022 Dec 21:e0128122. doi: 10.1128/aac.01281.
PubMed Abstract available

LIU X, Lei T, Yang Y, Zhang L, et al
Structural Basis of PER-1-Mediated Cefiderocol Resistance and Synergistic Inhibition of PER-1 by Cefiderocol in Combination with Avibactam or Durlobactam in Acinetobacter baumannii.
Antimicrob Agents Chemother. 2022;66:e0082822.
PubMed Abstract available

NOBREGA DE ALMEIDA J JR, Jimenez-Ortigosa C, Francisco EC, Colombo AL, et al
ERG11 Analysis among Clinical Isolates of Trichosporon asahii with Different Azole Susceptibility Profiles.
Antimicrob Agents Chemother. 2022;66:e0110122.
PubMed Abstract available

WEINMAIER T, Conzemius R, Bergman Y, Lewis S, et al
Validation and Application of Long-Read Whole-Genome Sequencing for Antimicrobial Resistance Gene Detection and Antimicrobial Susceptibility Testing.
Antimicrob Agents Chemother. 2022 Dec 19:e0107222. doi: 10.1128/aac.01072.
PubMed Abstract available

RUSSO TA, Carlino-MacDonald U, Alvarado CL, Davies CJ, et al
Penicillin Binding Protein 7/8 Is a Potential Drug Target in Carbapenem-Resistant Acinetobacter baumannii.
Antimicrob Agents Chemother. 2022 Dec 7:e0103322. doi: 10.1128/aac.01033.
PubMed Abstract available

RHODES NJ, Rohani R, Yarnold PR, Pawlowski AE, et al
Machine Learning To Stratify Methicillin-Resistant Staphylococcus aureus Risk among Hospitalized Patients with Community-Acquired Pneumonia.
Antimicrob Agents Chemother. 2022 Dec 6:e0102322. doi: 10.1128/aac.01023.
PubMed Abstract available

MILLER S, Goy K, She R, Spellberg B, et al
Antimicrobial Susceptibility Testing Performed in RPMI 1640 Reveals Azithromycin Efficacy against Carbapenem-Resistant Acinetobacter baumannii and Predicts In Vivo Outcomes in Galleria mellonella.
Antimicrob Agents Chemother. 2022 Dec 5:e0132022. doi: 10.1128/aac.01320.
PubMed Abstract available

November 2022

LIU Y, Shi J, Li L, Wu T, et al
Spontaneous Mutational Patterns and Novel Mutations for Delamanid Resistance in Mycobacterium tuberculosis.
Antimicrob Agents Chemother. 2022 Nov 30:e0053122. doi: 10.1128/aac.00531.
PubMed Abstract available

YU XH, Hao ZH, Liu PL, Liu MM, et al
Increased Expression of Efflux Pump norA Drives the Rapid Evolutionary Trajectory from Tolerance to Resistance against Ciprofloxacin in Staphylococcus aureus.
Antimicrob Agents Chemother. 2022 Nov 29:e0059422. doi: 10.1128/aac.00594.
PubMed Abstract available

MANSJO M, Karlsson Lindsjo O, Gronfors Seeth C, Groenheit R, et al
The ddn Trp20Stop Mutation and Its Association with Lineage 4.5 and Resistance to Delamanid and Pretomanid in Mycobacterium tuberculosis.
Antimicrob Agents Chemother. 2022 Nov 21:e0102622. doi: 10.1128/aac.01026.
PubMed Abstract available

PFALLER MA, Huband MD, Rhomberg PR, Bien PA, et al
Activities of Manogepix and Comparators against 1,435 Recent Fungal Isolates Collected during an International Surveillance Program (2020).
Antimicrob Agents Chemother. 2022;66:e0102822.
PubMed Abstract available

PANTEL L, Guerin F, Serri M, Gravey F, et al
Exploring Cluster-Dependent Antibacterial Activities and Resistance Pathways of NOSO-502 and Colistin against Enterobacter cloacae Complex Species.
Antimicrob Agents Chemother. 2022;66:e0077622.
PubMed Abstract available

ALBERTO-LEI F, Nodari CS, Streling AP, Bessa-Neto FO, et al
Characterization of a Carbapenem-Resistant BKC-1-Producing Clinical Isolate Belonging to the Pseudomonas putida Group from Brazil.
Antimicrob Agents Chemother. 2022 Nov 15:e0083922. doi: 10.1128/aac.00839.
PubMed Abstract available

SAH SK, Bhattacharya S, Yadav A, Husain F, et al
Multiple Genes of Candida albicans Influencing Echinocandin Susceptibility in Caspofungin-Adapted Mutants.
Antimicrob Agents Chemother. 2022 Nov 10:e0097722. doi: 10.1128/aac.00977.
PubMed Abstract available

MON AS, Ei PW, Htwe MM, Nyunt MH, et al
First Detection of Mycobacterium tuberculosis Clinical Isolates Harboring I491F Borderline Resistance rpoB Mutation in Myanmar.
Antimicrob Agents Chemother. 2022 Nov 7:e0092522. doi: 10.1128/aac.00925.
PubMed

CABELLOS C, Guillem L, Pelegrin I, Tubau F, et al
Penicillin- and Cephalosporin-Resistant Pneumococcal Meningitis: Treatment in the Real World and in Guidelines.
Antimicrob Agents Chemother. 2022 Nov 3:e0082022. doi: 10.1128/aac.00820.
PubMed Abstract available

October 2022

AN L, Tan J, Wang Y, Liu S, et al
Synergistic Effect of the Combination of Deferoxamine and Fluconazole In Vitro and In Vivo against Fluconazole-Resistant Candida Spp.
Antimicrob Agents Chemother. 2022 Oct 26:e0072522. doi: 10.1128/aac.00725.
PubMed Abstract available

KIM TY, Huh HJ, Lee GY, Choi MJ, et al
Evolution of Fluconazole Resistance Mechanisms and Clonal Types of Candida parapsilosis Isolates from a Tertiary Care Hospital in South Korea.
Antimicrob Agents Chemother. 2022 Oct 13:e0088922. doi: 10.1128/aac.00889.
PubMed Abstract available

HISATSUNE J, Tanimoto K, Kohara T, Myoken Y, et al
First Isolation of Vancomycin-Resistant Enterococcus faecium Carrying Plasmid-Borne vanD1.
Antimicrob Agents Chemother. 2022 Oct 12:e0102922. doi: 10.1128/aac.01029.
PubMed Abstract available

PLAUNT AJ, Rose SJ, Kang JY, Chen KJ, et al
Correction for Plaunt et al., "Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections".
Antimicrob Agents Chemother. 2022 Oct 12:e0125622. doi: 10.1128/aac.01256.
PubMed

YAO S, Wei D, Tang N, Song Y, et al
Efficient Suppression of Natural Plasmid-Borne Gene Expression in Carbapenem-Resistant Klebsiella pneumoniae Using a Compact CRISPR Interference System.
Antimicrob Agents Chemother. 2022 Oct 12:e0089022. doi: 10.1128/aac.00890.
PubMed Abstract available

September 2022

COX GW, Avery BP, Parmley EJ, Irwin RJ, et al
A One Health Genomic Investigation of Gentamicin Resistance in Escherichia coli from Human and Chicken Sources in Canada, 2014 to 2017.
Antimicrob Agents Chemother. 2022 Sep 27:e0067722. doi: 10.1128/aac.00677.
PubMed Abstract available

RUEGSEGGER L, Xiao J, Naziripour A, Kanumuambidi T, et al
Multidrug-Resistant Gram-Negative Bacteria in Burn Patients.
Antimicrob Agents Chemother. 2022;66:e0068822.
PubMed Abstract available

MEAD A, Toutain PL, Richez P, Pelligand L, et al
Quantitative Pharmacodynamic Characterization of Resistance versus Heteroresistance of Colistin in E. coli Using a Semimechanistic Modeling of Killing Curves.
Antimicrob Agents Chemother. 2022;66:e0079322.
PubMed Abstract available

PARK S, Russo R, Westfall L, Shrestha R, et al
A Novel Oral GyrB/ParE Dual Binding Inhibitor Effective against Multidrug-Resistant Neisseria gonorrhoeae and Other High-Threat Pathogens.
Antimicrob Agents Chemother. 2022;66:e0041422.
PubMed Abstract available

HALPERN-COHEN V, Blumberg EA
New Perspectives on Antimicrobial Agents: Maribavir.
Antimicrob Agents Chemother. 2022;66:e0240521.
PubMed Abstract available

LUTERBACH CL, Qiu H, Hanafin PO, Sharma R, et al
A Systems-Based Analysis of Mono- and Combination Therapy for Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections.
Antimicrob Agents Chemother. 2022 Sep 20:e0059122. doi: 10.1128/aac.00591.
PubMed Abstract available

HOBSON CA, Pierrat G, Tenaillon O, Bonacorsi S, et al
Klebsiella pneumoniae Carbapenemase Variants Resistant to Ceftazidime-Avibactam: an Evolutionary Overview.
Antimicrob Agents Chemother. 2022;66:e0044722.
PubMed Abstract available

STANTON RA, Campbell D, McAllister GA, Breaker E, et al
Whole-Genome Sequencing Reveals Diversity of Carbapenem-Resistant Pseudomonas aeruginosa Collected through CDC's Emerging Infections Program, United States, 2016-2018.
Antimicrob Agents Chemother. 2022 Sep 6:e0049622. doi: 10.1128/aac.00496.
PubMed Abstract available

August 2022

SARIS A, Qin W, van Linge CCA, Reijnders TDY, et al
The Azithromycin Pro-Drug CSY5669 Boosts Bacterial Killing While Attenuating Lung Inflammation Associated with Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2022 Aug 16:e0229821. doi: 10.1128/aac.02298.
PubMed Abstract available

POIREL L, Ortiz de la Rosa JM, Sakaoglu Z, Kusaksizoglu A, et al
NDM-35-Producing ST167 Escherichia coli Highly Resistant to beta-Lactams Including Cefiderocol.
Antimicrob Agents Chemother. 2022;66:e0031122.
PubMed Abstract available

EPLING BP, Powers JH 3rd
Cefiderocol and the Need for Higher-Quality Evidence: Methods Matter for Patients.
Antimicrob Agents Chemother. 2022;66:e0076622.
PubMed

VALCEK A, Nesporova K, Whiteway C, De Pooter T, et al
Genomic Analysis of a Strain Collection Containing Multidrug-, Extensively Drug-, Pandrug-, and Carbapenem-Resistant Modern Clinical Isolates of Acinetobacter baumannii.
Antimicrob Agents Chemother. 2022 Aug 15:e0089222. doi: 10.1128/aac.00892.
PubMed Abstract available

CHOCHUA S, Metcalf B, Li Z, Mathis S, et al
Invasive Group A Streptococcal Penicillin Binding Protein 2x Variants Associated with Reduced Susceptibility to beta-Lactam Antibiotics in the United States, 2015-2021.
Antimicrob Agents Chemother. 2022 Aug 15:e0080222. doi: 10.1128/aac.00802.
PubMed Abstract available

EDLIND T, Katiyar S
Intrinsically High Resistance of Candida glabrata to Hydrogen Peroxide and Its Reversal in a Fluconazole-Resistant Mutant.
Antimicrob Agents Chemother. 2022 Aug 2:e0072122. doi: 10.1128/aac.00721.
PubMed

July 2022

CHANG SC, Lin LC, Lu JJ
An lnu(A)-Carrying Multi-Resistance Plasmid Derived from Sequence Type 3 Methicillin-Resistant Staphylococcus lugdunensis May Contribute to Antimicrobial Resistance in Staphylococci.
Antimicrob Agents Chemother. 2022 Jul 25:e0019722. doi: 10.1128/aac.00197.
PubMed Abstract available

HARISH E, Sarkar A, Handelman M, Abo Kandil A, et al
Triazole Priming as an Adaptive Response and Gateway to Resistance in Aspergillus fumigatus.
Antimicrob Agents Chemother. 2022 Jul 20:e0045822. doi: 10.1128/aac.00458.
PubMed Abstract available

LIN IF, Lai CH, Lin SY, Lee CC, et al
Mutant Prevention Concentrations of Ciprofloxacin and Levofloxacin and Target Gene Mutations of Fluoroquinolones in Elizabethkingia anophelis.
Antimicrob Agents Chemother. 2022;66:e0030122.
PubMed Abstract available

PITOUT JDD, Peirano G, Chen L, DeVinney R, et al
Escherichia coli ST1193: Following in the Footsteps of E. coli ST131.
Antimicrob Agents Chemother. 2022;66:e0051122.
PubMed Abstract available

PITTON M, Oberhaensli S, Appiah F, Pagani JL, et al
Mutation to ispA Produces Stable Small-Colony Variants of Pseudomonas aeruginosa That Have Enhanced Aminoglycoside Resistance.
Antimicrob Agents Chemother. 2022;66:e0062122.
PubMed Abstract available

DIAZ-GARCIA J, Gomez A, Alcala L, Reigadas E, et al
Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution.
Antimicrob Agents Chemother. 2022 Jul 19:e0071022. doi: 10.1128/aac.00710.
PubMed Abstract available

KIM JH, Kim JH, Choe WH, Kwon SY, et al
Switching from Tenofovir-Based Combination Therapy to Tenofovir Monotherapy in Multidrug-Experienced Chronic Hepatitis B Patients: a 5-Year Experience at Two Centers.
Antimicrob Agents Chemother. 2022 Jul 13:e0027522. doi: 10.1128/aac.00275.
PubMed Abstract available

KONG X, Wang B, Chen X, Wang L, et al
Hinokiflavone Attenuates the Virulence of Methicillin-Resistant Staphylococcus aureus by Targeting Caseinolytic Protease P.
Antimicrob Agents Chemother. 2022 Jul 11:e0024022. doi: 10.1128/aac.00240.
PubMed Abstract available

June 2022

JACOBS SE, Jacobs JL, Dennis EK, Taimur S, et al
Candida auris Pan-Drug-Resistant to Four Classes of Antifungal Agents.
Antimicrob Agents Chemother. 2022 Jun 30:e0005322. doi: 10.1128/aac.00053.
PubMed Abstract available

YAMADA T, Yaguchi T, Maeda M, Alshahni MM, et al
Gene Amplification of CYP51B: a New Mechanism of Resistance to Azole Compounds in Trichophyton indotineae.
Antimicrob Agents Chemother. 2022;66:e0005922.
PubMed Abstract available

DOORLEY LA, Rybak JM, Berkow EL, Zhang Q, et al
Candida parapsilosis Mdr1B and Cdr1B Are Drivers of Mrr1-Mediated Clinical Fluconazole Resistance.
Antimicrob Agents Chemother. 2022 Jun 14:e0028922. doi: 10.1128/aac.00289.
PubMed Abstract available

ZHAO X, Jin Y, Bai F, Cheng Z, et al
Mutation of PA4292 in Pseudomonas aeruginosa Increases beta-Lactam Resistance through Upregulating Pyocyanin Production.
Antimicrob Agents Chemother. 2022 Jun 13:e0042122. doi: 10.1128/aac.00421.
PubMed Abstract available

SONG W, Wang L, Jin M, Guo X, et al
Punicalagin, an Inhibitor of Sortase A, Is a Promising Therapeutic Drug to Combat Methicillin-Resistant Staphylococcus aureus Infections.
Antimicrob Agents Chemother. 2022 Jun 2:e0022422. doi: 10.1128/aac.00224.
PubMed Abstract available

SHAO Y, Chen M, Luo J, Li D, et al
Serogroup Y Clonal Complex 23 Meningococcus in China Acquiring Penicillin Resistance from Commensal Neisseria lactamica Species.
Antimicrob Agents Chemother. 2022 Jun 2:e0238321. doi: 10.1128/aac.02383.
PubMed Abstract available

ZHOU Y, Zhong Z, Hu S, Wang J, et al
A Survey of Helicobacter pylori Antibiotic-Resistant Genotypes and Strain Lineages by Whole-Genome Sequencing in China.
Antimicrob Agents Chemother. 2022 Jun 2:e0218821. doi: 10.1128/aac.02188.
PubMed Abstract available

SHIVARATHRI R, Jenull S, Chauhan M, Singh A, et al
Comparative Transcriptomics Reveal Possible Mechanisms of Amphotericin B Resistance in Candida auris.
Antimicrob Agents Chemother. 2022 Jun 2:e0227621. doi: 10.1128/aac.02276.
PubMed Abstract available

ISHIKAWA K, Uehara Y, Mori N, Mikami Y, et al
In Vitro Activity and Clinical Efficacy of Faropenem against Third-Generation Cephalosporin-Resistant Escherichia coli and Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2022 Jun 1:e0012522. doi: 10.1128/aac.00125.
PubMed Abstract available

CHEN M, Zhong G, Wang S, Chen P, et al
Deletion of cox7c Results in Pan-Azole Resistance in Aspergillus fumigatus.
Antimicrob Agents Chemother. 2022 Jun 1:e0015122. doi: 10.1128/aac.00151.
PubMed Abstract available

May 2022

SOBEL JD, Akins R
Determining Susceptibility in Candida Vaginal Isolates.
Antimicrob Agents Chemother. 2022 May 23:e0236621. doi: 10.1128/aac.02366.
PubMed Abstract available

LI X, Le W, Lou X, Genco CA, et al
In Vitro Activity of Ertapenem against Neisseria gonorrhoeae Clinical Isolates with Decreased Susceptibility or Resistance to Extended-Spectrum Cephalosporins in Nanjing, China (2013 to 2019).
Antimicrob Agents Chemother. 2022;66:e0010922.
PubMed Abstract available

MURRAY GL, Bodiyabadu K, Vodstrcil LA, Machalek DA, et al
parC Variants in Mycoplasma genitalium: Trends over Time and Association with Moxifloxacin Failure.
Antimicrob Agents Chemother. 2022;66:e0027822.
PubMed Abstract available

DUNCAN LR, Wang W, Sader HS
In Vitro Potency and Spectrum of the Novel Polymyxin MRX-8 Tested against Clinical Isolates of Gram-Negative Bacteria.
Antimicrob Agents Chemother. 2022;66:e0013922.
PubMed Abstract available

PRASAD NK, Seiple IB, Cirz RT, Rosenberg OS, et al
Leaks in the Pipeline: a Failure Analysis of Gram-Negative Antibiotic Development from 2010 to 2020.
Antimicrob Agents Chemother. 2022;66:e0005422.
PubMed Abstract available

BAKER KM, Hoda S, Saha D, Gregor JB, et al
The Set1 Histone H3K4 Methyltransferase Contributes to Azole Susceptibility in a Species-Specific Manner by Differentially Altering the Expression of Drug Efflux Pumps and the Ergosterol Gene Pathway.
Antimicrob Agents Chemother. 2022;66:e0225021.
PubMed Abstract available

CHUA TP, Danielewski J, Bodiyabadu K, Bradshaw CS, et al
Impact of 16S rRNA Single Nucleotide Polymorphisms on Mycoplasma genitalium Organism Load with Doxycycline Treatment.
Antimicrob Agents Chemother. 2022;66:e0024322.
PubMed Abstract available

DESNOS-OLLIVIER M, Bretagne S, Lortholary O, Dromer F, et al
Echinocandins Susceptibility Patterns of 2,787 Yeast Isolates: Importance of the Thresholds for the Detection of FKS Mutations.
Antimicrob Agents Chemother. 2022;66:e0172521.
PubMed Abstract available

ERSOY SC, Manna AC, Proctor RA, Chambers HF, et al
The NaHCO3-Responsive Phenotype in Methicillin-Resistant Staphylococcus aureus (MRSA) Is Influenced by mecA Genotype.
Antimicrob Agents Chemother. 2022 May 16:e0025222. doi: 10.1128/aac.00252.
PubMed Abstract available

DIAMOND TL, Ngo W, Xu M, Goh SL, et al
Islatravir Has a High Barrier to Resistance and Exhibits a Differentiated Resistance Profile from Approved Nucleoside Reverse Transcriptase Inhibitors (NRTIs).
Antimicrob Agents Chemother. 2022 May 12:e0013322. doi: 10.1128/aac.00133.
PubMed Abstract available

FUCHS F, Aldejohann AM, Hoffmann AM, Walther G, et al
In Vitro Activity of Nitroxoline in Antifungal-Resistant Candida Species Isolated from the Urinary Tract.
Antimicrob Agents Chemother. 2022 May 11:e0226521. doi: 10.1128/aac.02265.
PubMed Abstract available

SUPANDY A, Mehta HH, Tran TT, Miller WR, et al
Evolution of Enterococcus faecium in Response to a Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies.
Antimicrob Agents Chemother. 2022 May 11:e0233321. doi: 10.1128/aac.02333.
PubMed Abstract available

CONKLE-GUTIERREZ D, Kim C, Ramirez-Busby SM, Modlin SJ, et al
Distribution of Common and Rare Genetic Markers of Second-Line-Injectable-Drug Resistance in Mycobacterium tuberculosis Revealed by a Genome-Wide Association Study.
Antimicrob Agents Chemother. 2022 May 9:e0207521. doi: 10.1128/aac.02075.
PubMed Abstract available

GARTLAND M, Cahn P, DeJesus E, Diaz RS, et al
Week 96 Genotypic and Phenotypic Results of the Fostemsavir Phase 3 BRIGHTE Study in Heavily Treatment-Experienced Adults Living with Multidrug-Resistant HIV-1.
Antimicrob Agents Chemother. 2022 May 3:e0175121. doi: 10.1128/aac.01751.
PubMed Abstract available

LAI MT, Feng M, Xu M, Ngo W, et al
Doravirine and Islatravir Have Complementary Resistance Profiles and Create a Combination with a High Barrier to Resistance.
Antimicrob Agents Chemother. 2022 May 2:e0222321. doi: 10.1128/aac.02223.
PubMed Abstract available

April 2022

MADDEN DE, Olagoke O, Baird T, Neill J, et al
Express Yourself: Quantitative Real-Time PCR Assays for Rapid Chromosomal Antimicrobial Resistance Detection in Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2022 Apr 25:e0020422. doi: 10.1128/aac.00204.
PubMed Abstract available

HOLLEY CL, Dhulipala V, Balthazar JT, Le Van A, et al
A Single Amino Acid Substitution in Elongation Factor G Can Confer Low-Level Gentamicin Resistance in Neisseria gonorrhoeae.
Antimicrob Agents Chemother. 2022 Apr 25:e0025122. doi: 10.1128/aac.00251.
PubMed Abstract available

SALAMA OE, Gerstein AC
Differential Response of Candida Species Morphologies and Isolates to Fluconazole and Boric Acid.
Antimicrob Agents Chemother. 2022 Apr 21:e0240621. doi: 10.1128/aac.02406.
PubMed Abstract available

KANO R, Kimura U, Noguchi H, Hiruma M, et al
Clinical Isolate of a Multi-Antifungal-Resistant Trichophyton rubrum.
Antimicrob Agents Chemother. 2022;66:e0239321.
PubMed Abstract available

ZWAMA M, Nishino K
Proximal Binding Pocket Arg717 Substitutions in Escherichia coli AcrB Cause Clinically Relevant Divergencies in Resistance Profiles.
Antimicrob Agents Chemother. 2022;66:e0239221.
PubMed Abstract available

KIM H, Mori S, Kenri T, Suzuki Y, et al
Molecular Characterization of Mycobacterium ulcerans DNA Gyrase and Identification of Mutations Reducing Susceptibility to Quinolones In Vitro.
Antimicrob Agents Chemother. 2022;66:e0190221.
PubMed Abstract available

ANDRADE ESN, Brandao JG, Silva JSD, Coriolano CRF, et al
Antimicrobial Resistance among Leprosy Patients in Brazil: Real-World Data Based on the National Surveillance Plan.
Antimicrob Agents Chemother. 2022 Apr 18:e0217021. doi: 10.1128/aac.02170.
PubMed Abstract available

VAN VLIET AHM, Thakur S, Prada JM, Mehat JW, et al
Genomic Screening of Antimicrobial Resistance Markers in UK and US Campylobacter Isolates Highlights Stability of Resistance over an 18-Year Period.
Antimicrob Agents Chemother. 2022 Apr 11:e0168721. doi: 10.1128/aac.01687.
PubMed Abstract available

March 2022

LIN X, Qin X, Wu X, Liao Y, et al
Markedly Increasing Antibiotic Resistance and Dual Treatment of Neisseria gonorrhoeae Isolates in Guangdong, China, from 2013 to 2020.
Antimicrob Agents Chemother. 2022 Mar 29:e0229421. doi: 10.1128/aac.02294.
PubMed Abstract available

SONG N, Zhou X, Li D, Li X, et al
A Proteomic Landscape of Candida albicans in the Stepwise Evolution to Fluconazole Resistance.
Antimicrob Agents Chemother. 2022 Mar 28:e0210521. doi: 10.1128/aac.02105.
PubMed Abstract available

LI J, Coste AT, Bachmann D, Sanglard D, et al
Deciphering the Mrr1/Mdr1 Pathway in Azole Resistance of Candida auris.
Antimicrob Agents Chemother. 2022 Mar 28:e0006722. doi: 10.1128/aac.00067.
PubMed Abstract available

BUTLER MS, Gigante V, Sati H, Paulin S, et al
Reply to Kaye and Belley, "Third-Generation Cephalosporin-Resistant Enterobacterales Are Critical Priority Pathogens, Too!"
Antimicrob Agents Chemother. 2022 Mar 24:e0022322. doi: 10.1128/aac.00223.
PubMed

KAYE KS, Belley A
Third-Generation Cephalosporin-Resistant Enterobacterales Are Critical Priority Pathogens, Too!
Antimicrob Agents Chemother. 2022 Mar 24:e0021322. doi: 10.1128/aac.00213.
PubMed

JI X, Kruger H, Wang Y, Fessler AT, et al
Tn560, a Novel Tn554 Family Transposon from Porcine Methicillin-Resistant Staphylococcus aureus ST398, Carries a Multiresistance Gene Cluster Comprising a Novel spc Gene Variant and the Genes lsa(E) and lnu(B).
Antimicrob Agents Chemother. 2022 Mar 22:e0194721. doi: 10.1128/aac.01947.
PubMed

FARRINGTON N, McEntee L, Johnson A, Unsworth J, et al
Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance.
Antimicrob Agents Chemother. 2022 Mar 22:e0218121. doi: 10.1128/aac.02181.
PubMed Abstract available

FALCONE M, Tiseo G, Leonildi A, Della Sala L, et al
Cefiderocol- Compared to Colistin-Based Regimens for the Treatment of Severe Infections Caused by Carbapenem-Resistant Acinetobacter baumannii.
Antimicrob Agents Chemother. 2022 Mar 21:e0214221. doi: 10.1128/aac.02142.
PubMed Abstract available

ROTHSTEIN TE, Cunningham SA, Rieke RA, Mainella JM, et al
Macrolide Resistance in Mycoplasma pneumoniae, Midwestern United States, 2014 to 2021.
Antimicrob Agents Chemother. 2022 Mar 21:e0243221. doi: 10.1128/aac.02432.
PubMed Abstract available

BURR LD, Taylor SL, Richard A, Schreiber V, et al
Assessment of Long-Term Macrolide Exposure on the Oropharyngeal Microbiome and Macrolide Resistance in Healthy Adults and Consequences for Onward Transmission of Resistance.
Antimicrob Agents Chemother. 2022 Mar 16:e0224621. doi: 10.1128/aac.02246.
PubMed Abstract available

SUH GA, Lodise TP, Tamma PD, Knisely JM, et al
Considerations for the Use of Phage Therapy in Clinical Practice.
Antimicrob Agents Chemother. 2022;66:e0207121.
PubMed Abstract available

SONG M, Zhang M, Lu J, Xie F, et al
Palmarumycin P3 Reverses Mrr1-Mediated Azole Resistance by Blocking the Efflux Pump Mdr1.
Antimicrob Agents Chemother. 2022;66:e0212621.
PubMed Abstract available

BUTLER MS, Gigante V, Sati H, Paulin S, et al
Analysis of the Clinical Pipeline of Treatments for Drug-Resistant Bacterial Infections: Despite Progress, More Action Is Needed.
Antimicrob Agents Chemother. 2022;66:e0199121.
PubMed Abstract available

APPANEAL HJ, Lopes VV, LaPlante KL, Caffrey AR, et al
Treatment, Clinical Outcomes, and Predictors of Mortality among a National Cohort of Admitted Patients with Acinetobacter baumannii Infection.
Antimicrob Agents Chemother. 2022;66:e0197521.
PubMed Abstract available

SAWATZKY P, Demczuk W, Lefebvre B, Allen V, et al
Increasing Azithromycin Resistance in Neisseria gonorrhoeae Due to NG-MAST 12302 Clonal Spread in Canada, 2015 to 2018.
Antimicrob Agents Chemother. 2022;66:e0168821.
PubMed Abstract available

LI LH, Lu HF, Liu YF, Lin YT, et al
FadACB and smeU1VWU2X Contribute to Oxidative Stress-Mediated Fluoroquinolone Resistance in Stenotrophomonas maltophilia.
Antimicrob Agents Chemother. 2022 Mar 14:e0204321. doi: 10.1128/aac.02043.
PubMed Abstract available

HICKERSON BT, Adams SE, Barman S, Miller L, et al
Pleiotropic Effects of Influenza H1, H3, and B Baloxavir-Resistant Substitutions on Replication, Sensitivity to Baloxavir, and Interferon Expression.
Antimicrob Agents Chemother. 2022 Mar 9:e0000922. doi: 10.1128/aac.00009.
PubMed Abstract available

SCHARN CR, Tickler IA, Tenover FC, Goering RV, et al
Characterization of SCCmec Instability in Methicillin-Resistant Staphylococcus aureus Affecting Adjacent Chromosomal Regions, Including the Gene for Staphylococcal Protein A (spa).
Antimicrob Agents Chemother. 2022 Mar 7:e0237421. doi: 10.1128/aac.02374.
PubMed Abstract available

VAHEDI-SHAHANDASHTI R, Dietl AM, Binder U, Nagl M, et al
Aspergillus terreus and the Interplay with Amphotericin B: from Resistance to Tolerance?
Antimicrob Agents Chemother. 2022 Mar 7:e0227421. doi: 10.1128/aac.02274.
PubMed Abstract available

February 2022

ROYER G, Ortiz de la Rosa JM, Vuillemin X, Lacombe B, et al
Reduced chlorhexidine susceptibility is associated with tetracycline resistance tet genes in clinical isolates of Escherichia coli.
Antimicrob Agents Chemother. 2022 Feb 28:AAC0197221. doi: 10.1128/AAC.01972.
PubMed Abstract available

NURJADI D, Kocer K, Chanthalangsy Q, Klein S, et al
New Delhi Metallo-Beta-Lactamase Facilitates the Emergence of Cefiderocol Resistance in Enterobacter cloacae.
Antimicrob Agents Chemother. 2022;66:e0201121.
PubMed Abstract available

KARLOWSKY JA, Hackel MA, Takemura M, Yamano Y, et al
In Vitro Susceptibility of Gram-Negative Pathogens to Cefiderocol in Five Consecutive Annual Multinational SIDERO-WT Surveillance Studies, 2014 to 2019.
Antimicrob Agents Chemother. 2022;66:e0199021.
PubMed Abstract available

SALINI S, Bhat SG, Naz S, Natesh R, et al
The error-prone polymerase DnaE2 mediates the evolution of antibiotic resistance in persister mycobacterial cells.
Antimicrob Agents Chemother. 2022 Feb 14:AAC0177321. doi: 10.1128/AAC.01773.
PubMed Abstract available

January 2022

KLINE A, Lionakis MS
Case Commentary: Long-term fosmanogepix use in a transplant recipient with disseminated aspergillosis caused by azole-resistant Aspergillus calidoustus.
Antimicrob Agents Chemother. 2022 Jan 24:aac0236821. doi: 10.1128/aac.02368.
PubMed Abstract available

LEW C, Pellitteri Hahn M, Scarlett C, Rottier A, et al
Proteomic Correlates of Enhanced Daptomycin Activity Following beta-Lactam Pre-Conditioning in Daptomycin-Resistant Methicillin-Resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2022 Jan 18:AAC0201721. doi: 10.1128/AAC.02017.
PubMed Abstract available

BRENNAN-KROHN T, Grote A, Rodriguez S, Kirby JE, et al
Transcriptomics reveals how minocycline-colistin synergy overcomes antibiotic resistance in multidrug-resistant Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2022 Jan 18:aac0196921. doi: 10.1128/aac.01969.
PubMed Abstract available

AKRONG G, Chauzy A, Aranzana-Climent V, Lacroix M, et al
A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro.
Antimicrob Agents Chemother. 2022;66:e0178921.
PubMed Abstract available

LIU M, Zhang W, Hu Y, Chen P, et al
Emergence of the cfr Gene in Vibrio diabolicus of Seafood Origin.
Antimicrob Agents Chemother. 2022;66:e0181921.
PubMed Abstract available

YU R, Chen Z, Schwarz S, Yao H, et al
Mobilization of tet(X4) by IS1 Family Elements in Porcine Escherichia coli Isolates.
Antimicrob Agents Chemother. 2022;66:e0159721.
PubMed Abstract available

HONG YP, Wang YW, Chen BH, Song HY, et al
RamAp Is an Efflux Pump Regulator Carried by an IncHI2 Plasmid.
Antimicrob Agents Chemother. 2022;66:e0115221.
PubMed Abstract available

EALES BM, Tam VH
Case Commentary: Novel Therapy for Multidrug-Resistant Acinetobacter baumannii Infection.
Antimicrob Agents Chemother. 2022;66:e0199621.
PubMed Abstract available

TENG JLL, Chan E, Dai ACH, Ng G, et al
In Vitro Susceptibility of Typhoidal, Nontyphoidal, and Extended-Spectrum-beta-Lactamase-Producing Salmonella to Ceftolozane/Tazobactam.
Antimicrob Agents Chemother. 2022;66:e0122421.
PubMed Abstract available

RAO S, Betancourt-Garcia M, Kare-Opaneye YO, Swierczewski BE, et al
Critically Ill Patient with Multidrug-Resistant Acinetobacter baumannii Respiratory Infection Successfully Treated with Intravenous and Nebulized Bacteriophage Therapy.
Antimicrob Agents Chemother. 2022;66:e0082421.
PubMed Abstract available

LONG H, Hu Y, Feng Y, Zong Z, et al
Genome analysis of Klebsiella oxytoca complex for antimicrobial resistance and virulence genes.
Antimicrob Agents Chemother. 2022 Jan 10:aac0218321. doi: 10.1128/aac.02183.
PubMed Abstract available

VU BG, Moye-Rowley WS
Azole-resistant alleles of ERG11 in Candida glabrata trigger activation of the Pdr1 and Upc2A transcription factors.
Antimicrob Agents Chemother. 2022 Jan 10:AAC0209821. doi: 10.1128/AAC.02098.
PubMed Abstract available

JEFFREY JL, St Clair M, Wang P, Wang C, et al
Impact of Integrase Sequences From HIV-1 Subtypes A6/A1 on the In Vitro Potency of Cabotegravir or Rilpivirine.
Antimicrob Agents Chemother. 2022 Jan 3:AAC0170221. doi: 10.1128/AAC.01702.
PubMed Abstract available

December 2021

TANAKA E, Wajima T, Uchiya KI, Nakaminami H, et al
Quinolone resistance is transferred horizontally via uptake signal sequence recognition in Haemophilus influenzae.
Antimicrob Agents Chemother. 2021 Dec 20:AAC0196721. doi: 10.1128/AAC.01967.
PubMed Abstract available

HUANG J, Guo S, Li X, Yuan F, et al
Nemonoxacin enhances antibacterial activity and anti-resistant mutation ability of vancomycin against methicillin-resistant Staphylococcus aureus in an in vitro dynamic pharmacokinetic/pharmacodynamic model.
Antimicrob Agents Chemother. 2021 Dec 13:AAC0180021. doi: 10.1128/AAC.01800.
PubMed Abstract available

KHALIFA HO, Hubka V, Watanabe A, Nagi M, et al
Prevalence of Antifungal Resistance, Genetic Basis of Acquired Azole and Echinocandin Resistance, and Genotyping of Candida krusei recovered from an International Collection.
Antimicrob Agents Chemother. 2021 Dec 6:AAC0185621. doi: 10.1128/AAC.01856.
PubMed Abstract available

November 2021

POON R, Basuino L, Satishkumar N, Chatterjee A, et al
Loss of GdpP function in Staphylococcus aureus leads to beta-lactam tolerance and enhanced evolution of beta-lactam resistance.
Antimicrob Agents Chemother. 2021 Nov 29:AAC0143121. doi: 10.1128/AAC.01431.
PubMed Abstract available

WEI J, Tong K, Wang H, Wen Y, et al
Intra-articular vancomycin for the prophylaxis of periprosthetic joint infection caused by methicillin-resistant S. aureus after total knee arthroplasty in a rat model: the dosage, efficacy, and safety.
Antimicrob Agents Chemother. 2021 Nov 22:AAC0164121. doi: 10.1128/AAC.01641.
PubMed Abstract available

VOGENSEN VB, Bolhuis MS, Sturkenboom MGG, van der Werf TS, et al
Clinical relevance of rifampicin-moxifloxacin interaction in isoniazid resistant/intolerant tuberculosis patients.
Antimicrob Agents Chemother. 2021 Nov 22:AAC0182921. doi: 10.1128/AAC.01829.
PubMed Abstract available

LEE YL, Ko WC, Hsueh PR
Geographic Patterns of Carbapenem-resistant Pseudomonas aeruginosa in the Asia-Pacific Region: Results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) program, 2015-2019.
Antimicrob Agents Chemother. 2021 Nov 22:AAC0200021. doi: 10.1128/AAC.02000.
PubMed Abstract available

LU CM, Cheng JS, Sun WC, Chen WC, et al
Tenofovir versus lamivudine followed by tenofovir in severe exacerbation of hepatitis B: a randomized controlled study.
Antimicrob Agents Chemother. 2021 Nov 22:AAC0166421. doi: 10.1128/AAC.01664.
PubMed Abstract available

CRANDON JL, Kuti JL, Nicolau DP
Erratum for Crandon et al., "Comparative Efficacies of Human Simulated Exposures of Telavancin and Vancomycin against Methicillin-Resistant Staphylococcus aureus with a Range of Vancomycin MICs in a Murine Pneumonia Model".
Antimicrob Agents Chemother. 2021;65:e0187821.
PubMed

LIU J, Xiao G, Zhou W, Yang J, et al
Hypothetical Protein gene1038 Contributes to Colistin Resistance in Aeromonas hydrophila.
Antimicrob Agents Chemother. 2021;65:e0150321.
PubMed

LUNA-TAPIA A, Parker JE, Kelly SL, Palmer GE, et al
Species-Specific Differences in C-5 Sterol Desaturase Function Influence the Outcome of Azole Antifungal Exposure.
Antimicrob Agents Chemother. 2021;65:e0104421.
PubMed Abstract available

LAZARUS JE, Warr AR, Westervelt KA, Hooper DC, et al
A Genome-Scale Antibiotic Screen in Serratia marcescens Identifies YdgH as a Conserved Modifier of Cephalosporin and Detergent Susceptibility.
Antimicrob Agents Chemother. 2021;65:e0078621.
PubMed Abstract available

RIVAS L, Alcalde-Rico M, Martinez JR, Moreno V, et al
Real-world Performance of Susceptibility Testing for Ceftolozane/Tazobactam Against Non-Carbapenemase-Producing Carbapenem-Resistant Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2021 Nov 15:AAC0165721. doi: 10.1128/AAC.01657.
PubMed Abstract available

PHAN MD, Peters KM, Alvarez Fraga L, Wallis SC, et al
Plasmid-mediated ciprofloxacin resistance imparts a selective advantage on Escherichia coli ST131.
Antimicrob Agents Chemother. 2021 Nov 15:AAC0214621. doi: 10.1128/AAC.02146.
PubMed Abstract available

SHARMA D, Paul RA, Rudramurthy SM, Kashyap N, et al
Impact of FKS1 genotype on echinocandin in-vitro susceptibility in Candida auris and in-vivo response in a murine model of infection.
Antimicrob Agents Chemother. 2021 Nov 15:AAC0165221. doi: 10.1128/AAC.01652.
PubMed Abstract available

NIIMI M, Niimi K, Tanabe K, Cannon RD, et al
Inhibitor Resistant Mutants Give Important Insights into Candida albicans ABC Transporter Cdr1 Substrate Specificity and Help Elucidate Efflux Pump Inhibition.
Antimicrob Agents Chemother. 2021 Nov 15:AAC0174821. doi: 10.1128/AAC.01748.
PubMed Abstract available

DICKER I, Jeffrey JL, Protack T, Lin Z, et al
GSK3640254 Is a Novel HIV-1 Maturation Inhibitor With an Optimized Virology Profile.
Antimicrob Agents Chemother. 2021 Nov 15:AAC0187621. doi: 10.1128/AAC.01876.
PubMed Abstract available

LIAO YS, Chen BH, Teng RH, Wang YW, et al
Antimicrobial resistance in Campylobacter coli and Campylobacter jejuni from human campylobacteriosis in Taiwan, 2016-2019.
Antimicrob Agents Chemother. 2021 Nov 8:AAC0173621. doi: 10.1128/AAC.01736.
PubMed Abstract available

KARAU MJ, Schmidt-Malan SM, Cunningham SA, Mandrekar JN, et al
Activity of Omadacycline in Rat Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
Antimicrob Agents Chemother. 2021 Nov 1:AAC0170321. doi: 10.1128/AAC.01703.
PubMed Abstract available

October 2021

MISHRA NN, Lew C, Abdelhady W, Lapitan CK, et al
Synergy Mechanisms of Daptomycin-Fosfomycin Combinations in Daptomycin-Susceptible and -Resistant Methicillin-Resistant S. aureus: In vitro, Ex vivo and In vivo Metrics.
Antimicrob Agents Chemother. 2021 Oct 25:AAC0164921. doi: 10.1128/AAC.01649.
PubMed Abstract available

ANAHTAR MN, Bramante JT, Xu J, Desrosiers LA, et al
Prediction of antimicrobial resistance in clinical Enterococcus faecium isolates using a rules-based analysis of whole genome sequences.
Antimicrob Agents Chemother. 2021 Oct 25:AAC0119621. doi: 10.1128/AAC.01196.
PubMed Abstract available

HERREN SC, Huemer M, Acevedo CT, Gomez-Mejia A, et al
Assessing antibiotic tolerance of Staphylococcus aureus derived directly from patients by the Replica Plating Tolerance Isolation System - REPTIS.
Antimicrob Agents Chemother. 2021 Oct 25:AAC0096721. doi: 10.1128/AAC.00967.
PubMed Abstract available

VAVRO C, Ruel T, Wiznia A, Montanez N, et al
Emergence of Resistance in HIV-1 Integrase With Dolutegravir Treatment in a Pediatric Population From the IMPAACT P1093 Study.
Antimicrob Agents Chemother. 2021 Oct 25:AAC0164521. doi: 10.1128/AAC.01645.
PubMed Abstract available

JIANG S, Zhuang H, Zhu F, Wei X, et al
The role of mprF mutations in "see-saw effect" of Daptomycin-resistant methicillin-resistant Staphylococcus aureus isolates.
Antimicrob Agents Chemother. 2021 Oct 18:AAC0129521. doi: 10.1128/AAC.01295.
PubMed Abstract available

DEMCZUK W, Martin I, Griffith A, Lefebvre B, et al
Linear regression equations to predict beta-lactam, macrolide, lincosamide and fluoroquinolone minimum inhibitory concentrations from molecular antimicrobial resistance determinants in Streptococcus pneumoniae.
Antimicrob Agents Chemother. 2021 Oct 18:AAC0137021. doi: 10.1128/AAC.01370.
PubMed Abstract available

KARLOWSKY JA, Hackel MA, Sahm DF
In Vitro Activity of Ceftibuten/VNRX-5236 against Urinary Tract Infection Isolates of Antimicrobial-Resistant Enterobacterales.
Antimicrob Agents Chemother. 2021 Oct 18:AAC0130421. doi: 10.1128/AAC.01304.
PubMed Abstract available

ALZAYN M, Dulyayangkul P, Satapoomin N, Heesom KJ, et al
OmpF Downregulation Mediated by Sigma E or OmpR Activation Confers Cefalexin Resistance in Escherichia coli in the Absence of Acquired beta-Lactamases.
Antimicrob Agents Chemother. 2021;65:e0100421.
PubMed Abstract available

NORDMANN P, Yao Y, Falgenhauer L, Sadek M, et al
Recent Emergence of Aztreonam-Avibactam Resistance in NDM and OXA-48 Carbapenemase-Producing Escherichia coli in Germany.
Antimicrob Agents Chemother. 2021;65:e0109021.
PubMed

CHENG Q, Zheng Z, Ye L, Chen S, et al
Identification of a Novel Metallo-beta-Lactamase, VAM-1, in a Foodborne Vibrio alginolyticus Isolate from China.
Antimicrob Agents Chemother. 2021;65:e0112921.
PubMed Abstract available

OSTRER L, Ji Y, Khodursky A
Identification and Characterization of Pleiotropic High-Persistence Mutations in the Beta Subunit of the Bacterial RNA Polymerase.
Antimicrob Agents Chemother. 2021;65:e0052221.
PubMed Abstract available

PORAMATHIKUL K, Wojnarski M, Sok S, Sokh V, et al
Update on Shigella and Nontyphoidal Salmonella Antimicrobial Drug Resistance: Implications on Empirical Treatment of Acute Infectious Diarrhea in Cambodia.
Antimicrob Agents Chemother. 2021;65:e0067121.
PubMed Abstract available

LOVEY A, Krel M, Borchardt A, Brady T, et al
Development of Novel Immunoprophylactic Agents against Multidrug-Resistant Gram-Negative Bacterial Infections.
Antimicrob Agents Chemother. 2021;65:e0098521.
PubMed Abstract available

ZAIDAN N, Hornak JP, Reynoso D
Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Pneumonia Successfully Treated with a Novel Antibiotic Combination.
Antimicrob Agents Chemother. 2021;65:e0092421.
PubMed Abstract available

BECKA SA, Zeiser ET, LiPuma JJ, Papp-Wallace KM, et al
Activity of Imipenem-Relebactam against Multidrug- and Extensively Drug-Resistant Burkholderia cepacia Complex and Burkholderia gladioli.
Antimicrob Agents Chemother. 2021;65:e0133221.
PubMed Abstract available

CUBRIA MB, Vega LA, Shropshire WC, Sanson MA, et al
Population genomics reveals distinct temporal association with the emergence of ST1 serotype V Group B Streptococcus and macrolide resistance in North America.
Antimicrob Agents Chemother. 2021 Oct 11:AAC0071421. doi: 10.1128/AAC.00714.
PubMed Abstract available

EVERT BJ, Slesarenko VA, Punnasseril JMJ, Taha, et al
Self-inhibitory peptides targeting the Neisseria gonorrhoeae MtrCDE efflux pump increase antibiotic susceptibility.
Antimicrob Agents Chemother. 2021 Oct 11:AAC0154221. doi: 10.1128/AAC.01542.
PubMed Abstract available

WILLIAMSON B, Wilk A, Guerrero KD, Mikulski TD, et al
Impact of Erg11 amino acid substitutions identified in Candida auris clade III isolates on triazole drug susceptibility.
Antimicrob Agents Chemother. 2021 Oct 11:AAC0162421. doi: 10.1128/AAC.01624.
PubMed Abstract available

DEKKER JG, Klaver B, Berkhout B, Das AT, et al
Mutations in the HIV-1 3'-polypurine tract can confer dolutegravir resistance.
Antimicrob Agents Chemother. 2021 Oct 11:AAC0102721. doi: 10.1128/AAC.01027.
PubMed Abstract available

JACQUELINE C, Caillon J, Meyer O, Dailly E, et al
Efficacy of Nano-Encapsulated Daptomycin in an Experimental Methicillin-Resistant Staphylococcus aureus (MRSA) Bone and Joint Infection Model.
Antimicrob Agents Chemother. 2021 Oct 4:AAC0076821. doi: 10.1128/AAC.00768.
PubMed Abstract available

September 2021

SABOUR S, Huang JY, Bhatnagar A, Gilbert SE, et al
Detection and Characterization of Targeted Carbapenem-Resistant Healthcare-Associated Threats: Findings from The Antibiotic Resistance Laboratory Network, 2017-2019.
Antimicrob Agents Chemother. 2021 Sep 27:AAC0110521. doi: 10.1128/AAC.01105.
PubMed Abstract available

COX GW, Parmley EJ, Avery BP, Irwin RJ, et al
A one health genomic investigation of gentamicin resistance in Salmonella from human and chicken sources in Canada, 2014-2017.
Antimicrob Agents Chemother. 2021 Sep 27:AAC0096621. doi: 10.1128/AAC.00966.
PubMed Abstract available

ASANTE-APPIAH E, Lai J, Wan H, Yang D, et al
Impact of HIV-1 Resistance-associated Mutations on Susceptibility to Doravirine: Analysis of Real-world Clinical Isolates.
Antimicrob Agents Chemother. 2021 Sep 27:AAC0121621. doi: 10.1128/AAC.01216.
PubMed Abstract available

DIAZ-GARCIA J, Mesquida A, Gomez A, Machado M, et al
Antifungal susceptibility testing identifies the abdominal cavity as a source of Candida glabrata resistant isolates.
Antimicrob Agents Chemother. 2021 Sep 27:AAC0124921. doi: 10.1128/AAC.01249.
PubMed Abstract available

INGLE DJ, Andersson P, Valcanis M, Wilmot M, et al
Genomic epidemiology and antimicrobial resistance mechanisms of imported typhoid in Australia.
Antimicrob Agents Chemother. 2021 Sep 20:AAC0120021. doi: 10.1128/AAC.01200.
PubMed Abstract available

KORRY BJ, Lee SYE, Chakrabarti AK, Choi AH, et al
Genotoxic Agents Produce Stressor-Specific Spectra of Spectinomycin Resistance Mutations Based on Mechanism of Action and Selection in Bacillus subtilis.
Antimicrob Agents Chemother. 2021;65:e0089121.
PubMed Abstract available

HE YZ, Yan JR, He B, Ren H, et al
A Transposon-Associated CRISPR/Cas9 System Specifically Eliminates both Chromosomal and Plasmid-Borne mcr-1 in Escherichia coli.
Antimicrob Agents Chemother. 2021;65:e0105421.
PubMed Abstract available

HANDELMAN M, Meir Z, Scott J, Shadkchan Y, et al
Point Mutation or Overexpression of Aspergillus fumigatus cyp51B, Encoding Lanosterol 14alpha-Sterol Demethylase, Leads to Triazole Resistance.
Antimicrob Agents Chemother. 2021;65:e0125221.
PubMed Abstract available

SLIPSKI CJ, Jamieson-Datzkiw TR, Zhanel GG, Bay DC, et al
Characterization of Proteobacterial Plasmid Integron-Encoded qac Efflux Pump Sequence Diversity and Quaternary Ammonium Compound Antiseptic Selection in Escherichia coli Grown Planktonically and as Biofilms.
Antimicrob Agents Chemother. 2021;65:e0106921.
PubMed Abstract available

POIREL L, Sadek M, Nordmann P
Contribution of PER-Type and NDM-Type beta-Lactamases to Cefiderocol Resistance in Acinetobacter baumannii.
Antimicrob Agents Chemother. 2021;65:e0087721.
PubMed Abstract available

CRASS RL, Al Naimi T, Wen B, Souza E, et al
Pharmacokinetics of Polymyxin B in Hospitalized Adults with Cystic Fibrosis.
Antimicrob Agents Chemother. 2021;65:e0079221.
PubMed Abstract available

HU M, Li Z, Li D, Chen F, et al
Long Terminal Repeat Retrotransposon Afut4 promotes azole resistance of Aspergillus fumigatus by enhancing the expression of sac1 gene.
Antimicrob Agents Chemother. 2021 Sep 13:AAC0029121. doi: 10.1128/AAC.00291.
PubMed Abstract available

TYMOSZEWSKA A, Ovchinnikov KV, Diep DB, SLodownik M, et al
Lactococcus lactis resistance to aureocin A53- and enterocin L50-like bacteriocins and membrane-targeting peptide antibiotics relies on the YsaCB-KinG-LlrG four-component system.
Antimicrob Agents Chemother. 2021 Sep 13:AAC0092121. doi: 10.1128/AAC.00921.
PubMed Abstract available

August 2021

PETRAITIS V, Petraitiene R, Kavaliauskas P, Naing E, et al
Pharmacokinetics, Tissue Distribution, and Efficacy of VIO-001 (Meropenem/Piperacillin/Tazobactam) for Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia in Immunocompetent Rabbits with Chronic Indwelling Vascular Catheters.
Antimicrob Agents Chemother. 2021 Aug 30:AAC0116821. doi: 10.1128/AAC.01168.
PubMed Abstract available

VARGAS R JR, Freschi L, Spitaleri A, Tahseen S, et al
The role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in Mycobacterium tuberculosis complex.
Antimicrob Agents Chemother. 2021 Aug 30:AAC0116421. doi: 10.1128/AAC.01164.
PubMed Abstract available

HOWARD-ANDERSON J, van Duin D
Uncertainty in evaluating treatment outcomes in carbapenem-resistant Acinetobacter baumannii infections.
Antimicrob Agents Chemother. 2021 Aug 23:AAC0142421. doi: 10.1128/AAC.01424.
PubMed Abstract available

MUKHERJEE S, Blankenship HM, Rodrigues JA, Mosci RE, et al
Antibiotic susceptibility profiles and frequency of resistance genes in clinical Shiga toxin-producing Escherichia coli isolates from Michigan over a 14-year period.
Antimicrob Agents Chemother. 2021 Aug 23:AAC0118921. doi: 10.1128/AAC.01189.
PubMed Abstract available

PASCUA PNQ, Jones JC, Marathe BM, Seiler P, et al
Baloxavir treatment delays influenza B virus transmission in ferrets and results in limited generation of drug-resistant variants.
Antimicrob Agents Chemother. 2021 Aug 23:AAC0113721. doi: 10.1128/AAC.01137.
PubMed Abstract available

WANG CH, Siu LK, Chang FY, Tsai YK, et al
Erratum for Wang et al., "A Novel Deletion Mutation in pmrB Contributes to Concurrent Colistin Resistance in Carbapenem-Resistant Escherichia coli Sequence Type 405 of Clinical Origin".
Antimicrob Agents Chemother. 2021;65:e0137421.
PubMed

WEI J, Wen Y, Tong K, Wang H, et al
Local Application of Vancomycin in One-Stage Revision of Prosthetic Joint Infection Caused by Methicillin-Resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2021;65:e0030321.
PubMed Abstract available

ABDUL-MUTAKABBIR JC, Nguyen L, Maassen PT, Stamper KC, et al
In Vitro Antibacterial Activity of Cefiderocol against Multidrug-Resistant Acinetobacter baumannii.
Antimicrob Agents Chemother. 2021;65:e0264620.
PubMed Abstract available

CHOQUET M, Lohou E, Pair E, Sonnet P, et al
Efflux Pump Overexpression Profiling in Acinetobacter baumannii and Study of New 1-(1-Naphthylmethyl)-Piperazine Analogs as Potential Efflux Inhibitors.
Antimicrob Agents Chemother. 2021;65:e0071021.
PubMed Abstract available

GILL CM, Aktathorn E, Alfouzan W, Bourassa L, et al
Elevated MICs of Susceptible Anti-Pseudomonal Cephalosporins in Non-Carbapenemase-Producing, Carbapenem-Resistant Pseudomonas aeruginosa: Implications for Dose Optimization.
Antimicrob Agents Chemother. 2021 Aug 16:AAC0120421. doi: 10.1128/AAC.01204.
PubMed Abstract available

NGWALERO P, Brust JCM, van Beek SW, Wasserman S, et al
Relationship between plasma and intracellular concentrations of bedaquiline and its M2 metabolite in South African patients with rifampin-resistant TB.
Antimicrob Agents Chemother. 2021 Aug 9:AAC0239920. doi: 10.1128/AAC.02399.
PubMed Abstract available

JEHANNE Q, Benejat L, Ducournau A, Domingues-Martins C, et al
Emergence of erythromycin resistance methyltransferases in Campylobacter coli strains in France.
Antimicrob Agents Chemother. 2021 Aug 9:AAC0112421. doi: 10.1128/AAC.01124.
PubMed Abstract available

HORWICH-SCHOLEFIELD S, Lloyd T, Varghese V, Yette E, et al
Imipenem-Relebactam Susceptibility and Genotypic Characteristics of Carbapenem-Resistant Enterobacterales (CRE) Identified during Population-Based Surveillance.
Antimicrob Agents Chemother. 2021 Aug 9:AAC0228820. doi: 10.1128/AAC.02288.
PubMed Abstract available

ESPINEL-INGROFF A, Sasso M, Turnidge J, Arendrup M, et al
Etest ECVs/ECOFFs for detection of resistance in prevalent and three non-prevalent Candida spp. to triazoles and amphotericin B and Aspergillus spp. to caspofungin: Further assessment of modal variability.
Antimicrob Agents Chemother. 2021 Aug 9:AAC0109321. doi: 10.1128/AAC.01093.
PubMed Abstract available

PRUSSING C, Canulla T, Singh N, McAuley P, et al
Characterization of the first carbapenem-resistant Pseudomonas aeruginosa clinical isolate harboring blaSIM-1 from the United States.
Antimicrob Agents Chemother. 2021 Aug 2:AAC0106621. doi: 10.1128/AAC.01066.
PubMed Abstract available

KULARATNE RS, Kufa T, Gumede L, Maseko DV, et al
Demographic and behavioural risk factors associated with reduced susceptibility of Neisseria gonorrhoeae to first-line antimicrobials in South African men with gonococcal urethral discharge.
Antimicrob Agents Chemother. 2021 Aug 2:AAC0038921. doi: 10.1128/AAC.00389.
PubMed Abstract available

July 2021

KAWAI A, Suzuki M, Tsukamoto K, Minato Y, et al
Functional and Structural Characterization of Acquired Pan-Aminoglycoside Resistance 16S rRNA Methyltransferase NpmB1.
Antimicrob Agents Chemother. 2021 Jul 26:AAC0100921. doi: 10.1128/AAC.01009.
PubMed Abstract available

WANG J, Ma W, Fang Y, Liang H, et al
Core oligosaccharide portion of lipopolysaccharide plays important roles on multiple antibiotic resistance in Escherichia coli.
Antimicrob Agents Chemother. 2021 Jul 26:AAC0034121. doi: 10.1128/AAC.00341.
PubMed Abstract available

GILL CM, Brink A, Chu CY, Coetzee J, et al
The Phenotypic/Genotypic Profile of OXA-10-like harboring, Carbapenem-Resistant Pseudomonas aeruginosa: Using Validated Pharmacokinetic/Pharmacodynamic in vivo Models to Further Evaluate Enzyme Functionality and Clinical Implications.
Antimicrob Agents Chemother. 2021 Jul 26:AAC0127421. doi: 10.1128/AAC.01274.
PubMed Abstract available

SHAHEEN SK, Juvvadi PR, Allen Iv J, Shwab EK, et al
In vitro activity of APX2041, a new GWT1-inhibitor and in vivo efficacy of the prodrug APX2104 against Aspergillus fumigatus.
Antimicrob Agents Chemother. 2021 Jul 26:AAC0068221. doi: 10.1128/AAC.00682.
PubMed Abstract available

MITCHEV N, Singh R, Allam M, Kwenda S, et al
Antimicrobial resistance mechanisms, MLST and NG-STAR sequence types of diverse Neisseria gonorrhoeae isolates in KwaZulu-Natal, South Africa.
Antimicrob Agents Chemother. 2021 Jul 19:AAC0075921. doi: 10.1128/AAC.00759.
PubMed Abstract available

LE C, Pimentel C, Tuttobene MR, Subils T, et al
Interplay between meropenem and human serum albumin on expression of carbapenem resistance genes and natural competence in Acinetobacter baumannii.
Antimicrob Agents Chemother. 2021 Jul 19:AAC0101921. doi: 10.1128/AAC.01019.
PubMed Abstract available

HANDELMAN M, Morogovsky A, Liu W, Ben-Ami R, et al
Triazole resistant Aspergillus fumigatus in an Israeli patient with Chronic Cavitary Pulmonary Aspergillosis due to a novel E306K Substitution in Hmg1.
Antimicrob Agents Chemother. 2021 Jul 19:AAC0108921. doi: 10.1128/AAC.01089.
PubMed Abstract available

SARDANA K, Gupta A, Sadhasivam S, Gautam RK, et al
Checkerboard Analysis To Evaluate Synergistic Combinations of Existing Antifungal Drugs and Propylene Glycol Monocaprylate in Isolates from Recalcitrant Tinea Corporis and Cruris Patients Harboring Squalene Epoxidase Gene Mutation.
Antimicrob Agents Chemother. 2021;65:e0032121.
PubMed Abstract available

CHEW KL, Octavia S, Lai D, Lin RTP, et al
Genomic Characterization of Klebsiella quasipneumoniae from Clinical Specimens in Singapore.
Antimicrob Agents Chemother. 2021;65:e0041221.
PubMed Abstract available

MCCREARY EK, Heil EL, Tamma PD
New Perspectives on Antimicrobial Agents: Cefiderocol.
Antimicrob Agents Chemother. 2021;65:e0217120.
PubMed Abstract available

ZUBYK HL, Wright GD
CrpP Is Not a Fluoroquinolone-Inactivating Enzyme.
Antimicrob Agents Chemother. 2021;65:e0077321.
PubMed

KONG X, Tang C, Singh A, Ahmed SA, et al
Antifungal Susceptibility and Mutations in the Squalene Epoxidase Gene in Dermatophytes of the Trichophyton mentagrophytes Species Complex.
Antimicrob Agents Chemother. 2021;65:e0005621.
PubMed Abstract available

SERRANO-LOBO J, Gomez A, Rodriguez-Sanchez B, Munoz P, et al
Azole resistant Aspergillus fumigatus clinical isolate screening in azole-containing agar plates (EUCAST E.Def 10.1): low impact of plastic trays used and poor performance in cryptic species.
Antimicrob Agents Chemother. 2021 Jul 12:AAC0048221. doi: 10.1128/AAC.00482.
PubMed Abstract available

POUVARET A, Dureault A, Garcia-Hermoso D, Serris A, et al
Combined high dose caspofungin and liposomal amphotericin B for the treatment of azole-resistant cerebral aspergillosis.
Antimicrob Agents Chemother. 2021 Jul 12:AAC0047421. doi: 10.1128/AAC.00474.
PubMed Abstract available

BIGGEL M, Nuesch-Inderbinen M, Jans C, Stevens MJA, et al
Genetic context of optrA and poxtA in florfenicol-resistant enterococci isolated from flowing surface water in Switzerland.
Antimicrob Agents Chemother. 2021 Jul 12:AAC0108321. doi: 10.1128/AAC.01083.
PubMed Abstract available

WESTGEEST AC, Schippers EF, Delfos NM, Ellerbroek LJ, et al
Complicated carriage with methicillin-resistant Staphylococcus aureus (MRSA): evaluation of the effectiveness of decolonization regimens advised in the Dutch national guideline.
Antimicrob Agents Chemother. 2021 Jul 6:AAC0025721. doi: 10.1128/AAC.00257.
PubMed Abstract available

TRAUNER A, Banaei-Esfahani A, Gygli SM, Warmer P, et al
Expression dysregulation as a mediator of fitness costs in antibiotic resistance.
Antimicrob Agents Chemother. 2021 Jul 6:AAC0050421. doi: 10.1128/AAC.00504.
PubMed Abstract available

CHEN L, Han X, Li Y, Li M, et al
Assessment of mortality-related risk factors and effective antimicrobial regimens for the treatment of bloodstream infections caused by carbapenem-resistant Enterobacterales.
Antimicrob Agents Chemother. 2021 Jul 6:AAC0069821. doi: 10.1128/AAC.00698.
PubMed Abstract available

MAPHANGA TG, Naicker SD, Kwenda S, Munoz JF, et al
In-vitro antifungal resistance of Candida auris isolates from bloodstream infections, South Africa.
Antimicrob Agents Chemother. 2021 Jul 6:AAC0051721. doi: 10.1128/AAC.00517.
PubMed Abstract available

June 2021

SOMPRASONG N, Yi J, Hall CM, Webb JR, et al
Conservation of resistance nodulation cell division efflux pump mediated antibiotic resistance in Burkholderia cepacia complex and Burkholderia pseudomallei complex species.
Antimicrob Agents Chemother. 2021 Jun 28:AAC0092021. doi: 10.1128/AAC.00920.
PubMed Abstract available

WERNGREN J, Mansjo M, Glader M, Hoffner S, et al
Detection of pyrazinamide heteroresistance in Mycobacterium tuberculosis.
Antimicrob Agents Chemother. 2021 Jun 28:AAC0072021. doi: 10.1128/AAC.00720.
PubMed Abstract available

FERREIRA S, Silva AL, Tomas J, Mateus C, et al
Characterization of AreABC, an RND-type efflux system involved in antimicrobial resistance of Aliarcobacter butzleri.
Antimicrob Agents Chemother. 2021 Jun 21:AAC0072921. doi: 10.1128/AAC.00729.
PubMed Abstract available

GONZALEZ-JIMENEZ I, Garcia-Rubio R, Monzon S, Lucio J, et al
Multi-resistance to non-azole fungicides in Aspergillus fumigatus TR34/L98H azole resistant isolates.
Antimicrob Agents Chemother. 2021 Jun 21:AAC0064221. doi: 10.1128/AAC.00642.
PubMed Abstract available

PLAUNT AJ, Rose SJ, Kang JY, Chen KJ, et al
Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections.
Antimicrob Agents Chemother. 2021;65:e0031621.
PubMed Abstract available

KORNELSEN V, Kumar A
Update on Multidrug Resistance Efflux Pumps in Acinetobacter spp.
Antimicrob Agents Chemother. 2021;65:e0051421.
PubMed Abstract available

ZARROUK K, Zhu X, Pham VD, Goyette N, et al
Impact of Amino Acid Substitutions in Region II and Helix K of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Resistance to Foscarnet.
Antimicrob Agents Chemother. 2021;65:e0039021.
PubMed Abstract available

LIZZA BD, Betthauser KD, Ritchie DJ, Micek ST, et al
New Perspectives on Antimicrobial Agents: Ceftolozane-Tazobactam.
Antimicrob Agents Chemother. 2021;65:e0231820.
PubMed Abstract available

GUTHRIDGE I, Smith S, Law M, Binotto E, et al
The efficacy and safety of intravenous lincosamide therapy in methicillin-resistant Staphylococcus aureus bacteremia.
Antimicrob Agents Chemother. 2021 Jun 14:AAC0034321. doi: 10.1128/AAC.00343.
PubMed Abstract available

TOYOTOME T, Onishi K, Sato M, Kusuya Y, et al
Identification of novel mutations contributing to azole tolerance of Aspergillus fumigatus through in vitro exposure to tebuconazole.
Antimicrob Agents Chemother. 2021 Jun 14:AAC0265720. doi: 10.1128/AAC.02657.
PubMed Abstract available

HUANG DB, Gaukel E, Kerzee N, Borroto-Esoda K, et al
Efficacy of Anti-Staphylococcal Lysin, LSVT-1701, in Combination with Daptomycin in Experimental Left-Sided Infective Endocarditis Due to Methicillin-Resistant Staphylococcus aureus (MRSA).
Antimicrob Agents Chemother. 2021 Jun 7:AAC0050821. doi: 10.1128/AAC.00508.
PubMed Abstract available

LEW C, Mishra NN, Bayer AS, Rose WE, et al
beta-lactam-induced cell envelope adaptations, not solely enhanced daptomycin binding, underlies daptomycin-beta-lactam synergy in methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother. 2021 Jun 7:AAC0035621. doi: 10.1128/AAC.00356.
PubMed Abstract available

GUO Q, Zhang Y, Fan J, Zhang H, et al
MAB_2355c Confers Macrolide Resistance in Mycobacterium abscessus by Ribosome Protection.
Antimicrob Agents Chemother. 2021 Jun 7:AAC0033021. doi: 10.1128/AAC.00330.
PubMed Abstract available

ABOU FAYAD AG, Haraoui LP, Sleiman A, Jaafar M, et al
Diversity of sequence types and impact of fitness cost among carbapenem-resistant Acinetobacter baumannii isolates from Tripoli, Libya.
Antimicrob Agents Chemother. 2021 Jun 7:AAC0027721. doi: 10.1128/AAC.00277.
PubMed Abstract available

WANG C, Yin M, Zhang X, Guo Q, et al
Identification of qnrE3 and qnrE4, new transferable quinolone resistance qnrE family genes originating from Enterobacter mori and E. asburiae, respectively.
Antimicrob Agents Chemother. 2021 Jun 7:AAC0045621. doi: 10.1128/AAC.00456.
PubMed Abstract available

LUCASSEN K, Gerson S, Xanthopoulou K, Wille J, et al
Comparison of the A. baumannii reference strains ATCC 17978 and ATCC 19606 in antimicrobial resistance mediated by the AdeABC efflux pump.
Antimicrob Agents Chemother. 2021 Jun 7:AAC0057021. doi: 10.1128/AAC.00570.
PubMed Abstract available

BACCANI I, Antonelli A, Di Pilato V, Coppi M, et al
Detection of poxtA2, a presumptive poxtA ancestor, in a plasmid from a linezolid-resistant Enterococcus gallinarum.
Antimicrob Agents Chemother. 2021 Jun 7:AAC0069521. doi: 10.1128/AAC.00695.
PubMed Abstract available

BHATNAGAR A, Boyd S, Sabour S, Bodnar J, et al
Aztreonam-Avibactam Susceptibility Testing Program for Metallo-beta-lactamase-producing Enterobacterales in the Antibiotic Resistance Laboratory Network, March 2019-December 2020.
Antimicrob Agents Chemother. 2021 Jun 1:AAC0048621. doi: 10.1128/AAC.00486.
PubMed Abstract available

May 2021

RUBIO AM, Kline EG, Jones CE, Chen L, et al
In Vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-Emergent Resistance to Ceftolozane-Tazobactam.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

SOLIMAN AM, Ramadan H, Zarad H, Sugawara Y, et al
Coproduction of Tet(X7) Conferring High-Level Tigecycline Resistance, Fosfomycin FosA4, and Colistin Mcr-1.1 in Escherichia coli Strains from Chickens in Egypt.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

DESNOS-OLLIVIER M, Lortholary O, Bretagne S, Dromer F, et al
Azole Susceptibility Profiles of More than 9,000 Clinical Yeast Isolates Belonging to 40 Common and Rare Species.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

MOIRANGTHEM R, Kumar K, Kaur R
Two Functionally Redundant FK506-Binding Proteins Regulate Multidrug Resistance Gene Expression and Govern Azole Antifungal Resistance.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

SOBEL JD, Borroto-Esoda K, Azie N, Angulo D, et al
In Vitro pH Activity of Ibrexafungerp Against Fluconazole-susceptible and -resistant Candida Isolates from Women with Vulvovaginal Candidiasis.
Antimicrob Agents Chemother. 2021 May 17. pii: AAC.00562.
PubMed Abstract available

CHEUNG CHP, Alorabi M, Hamilton F, Takebayashi Y, et al
Trade-Offs Between Antibacterial Resistance and Fitness Cost in the Production of Metallo-beta-Lactamases by Enteric Bacteria Manifest as Sporadic Emergence of Carbapenem Resistance in a Clinical Setting.
Antimicrob Agents Chemother. 2021 May 10. pii: AAC.02412.
PubMed Abstract available

RUELENS P, de Visser JAGM
Choice of beta-lactam resistance pathway depends critically on initial antibiotic concentration.
Antimicrob Agents Chemother. 2021 May 10. pii: AAC.00471.
PubMed Abstract available

MCGUIRE RJ, Yu SC, Payne PRO, Lai AM, et al
A Pragmatic Machine Learning Model to Predict Carbapenem Resistance.
Antimicrob Agents Chemother. 2021 May 10. pii: AAC.00063.
PubMed Abstract available

KAZMIERCZAK KM, Karlowsky JA, de Jonge BLM, Stone GG, et al
Epidemiology of Carbapenem Resistance Determinants Identified in Meropenem-nonsusceptible Enterobacterales collected as part of a Global Surveillance Program, 2012-2017.
Antimicrob Agents Chemother. 2021 May 10. pii: AAC.02000.
PubMed Abstract available

DARLOW CA, Docobo-Perez F, Farrington N, Johnson A, et al
Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.
Antimicrob Agents Chemother. 2021 May 10. pii: AAC.00293.
PubMed Abstract available

FREDERICKS LR, Lee MD, Eckert HR, Li S, et al
Vaginal Isolates of Candida glabrata are Uniquely Susceptible to Ionophoric Killer Toxins Produced by Saccharomyces cerevisiae.
Antimicrob Agents Chemother. 2021 May 10. pii: AAC.02450.
PubMed Abstract available

MOK S, Roycroft E, Flanagan PR, Montgomery L, et al
Overcoming the Challenges of Pyrazinamide Susceptibility Testing in Clinical Mycobacterium tuberculosis isolates.
Antimicrob Agents Chemother. 2021 May 10. pii: AAC.02617.
PubMed Abstract available

JANICE J, Agyepong N, Owusu-Ofori A, Govinden U, et al
Carbapenem-resistance determinants acquired through novel chromosomal integrations in XDR Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2021 May 3. pii: AAC.00289.
PubMed Abstract available

LIANG T, Yang X, Li R, Yang E, et al
Emergence of W272C Substitution in Hmg1 in a Triazole-Resistant Isolate of Aspergillus fumigatus from a Chinese Patient with Chronic Cavitary Pulmonary Aspergillosis.
Antimicrob Agents Chemother. 2021 May 3. pii: AAC.00263.
PubMed Abstract available

April 2021

LEY SD, Pillay S, Streicher EM, van der Heijden YF, et al
Melting the Eis: non-detection of kanamycin resistance markers by routine diagnostic tests and identification of new eis-promoter variants.
Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.02502.
PubMed Abstract available

KIM DH, Kim SY, Koh WJ, Jhun BW, et al
In Vitro Activity of Oxazolidinone against Nontuberculous Mycobacteria, Including Macrolide-Resistant Clinical Isolates.
Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.02306.
PubMed Abstract available

SONNENKALB L, Strohe G, Dreyer V, Andres S, et al
Microevolution of Mycobacterium tuberculosis hetero-resistance subpopulations in a patient receiving 27 years of tuberculosis treatment in Germany.
Antimicrob Agents Chemother. 2021 Apr 26. pii: AAC.02520.
PubMed Abstract available

CRANE JK, Alvarado CL, Sutton MD
Role of the SOS Response in the Generation of Antibiotic Resistance In Vivo.
Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.00013.
PubMed Abstract available

REHMAN A, Jeukens J, Levesque RC, Lamont IL, et al
Gene-gene interactions dictate ciprofloxacin resistance in Pseudomonas aeruginosa and facilitate prediction of resistance phenotype from genome sequence data.
Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.02696.
PubMed Abstract available

YAO D, Zhang G, Chen W, Chen J, et al
Pyrogallol and Fluconazole Interact Synergistically In Vitro Against Candida glabrata Through an Efflux-Associated Mechanism.
Antimicrob Agents Chemother. 2021 Apr 19. pii: AAC.00100.
PubMed Abstract available

OKOLIEGBE IN, Hijazi K, Cooper K, Ironside C, et al
Trends of antimicrobial resistance and combination susceptibility testing of cystic fibrosis multidrug-resistant Pseudomonas aeruginosa: A ten-year update.
Antimicrob Agents Chemother. 2021 Apr 5. pii: AAC.02483.
PubMed Abstract available

POULSEN JS, Madsen AM, White JK, Nielsen JL, et al
Physiological responses of Aspergillus niger challenged with itraconazole.
Antimicrob Agents Chemother. 2021 Apr 5. pii: AAC.02549.
PubMed Abstract available

March 2021

MENGUAL-CHULIA B, Alonso-Cordero A, Cano L, Del Mar Mosquera M, et al
Surveillance of Influenza A resistance to polymerase complex inhibitors by whole genome analysis, 2016-17, 2017-18 and 2018-19 Seasons, Eastern Spain.
Antimicrob Agents Chemother. 2021 Mar 29. pii: AAC.02718.
PubMed Abstract available

MASUKO A, Takata I, Fujita K, Okumura H, et al
In Vitro and In Vivo Activities of TP0480066, a Novel Topoisomerase Inhibitor, against Neisseria gonorrhoeae.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

BOOT W, Schmid T, D'Este M, Guillaume O, et al
A Hyaluronic Acid Hydrogel Loaded with Gentamicin and Vancomycin Successfully Eradicates Chronic Methicillin-Resistant Staphylococcus aureus Orthopedic Infection in a Sheep Model.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

NAKAMURA R, Oota M, Matsumoto S, Sato T, et al
In Vitro Activity and In Vivo Efficacy of Cefiderocol against Stenotrophomonas maltophilia.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

MIRA PM, Ostman B, Guzman-Cole C, Sindi S, et al
Adaptive Processes Change as Multiple Functions Evolve.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

DIAZ-GARCIA J, Mesquida A, Sanchez-Carrillo C, Reigadas E, et al
Monitoring the Epidemiology and Antifungal Resistance of Yeasts Causing Fungemia in a Tertiary Care Hospital in Madrid, Spain: Any Relevant Changes in the Last 13 Years?
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

CAMP J, Schuster S, Vavra M, Schweigger T, et al
Limited Multidrug Resistance Efflux Pump Overexpression among Multidrug-Resistant Escherichia coli Strains of ST131.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

CHENG J, Yan J, Reyna Z, Slarve M, et al
Synergistic Rifabutin and Colistin Reduce Emergence of Resistance When Treating Acinetobacter baumannii.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

ARDIZZONI E, Ariza E, Mulengwa D, Mpala Q, et al
Thin layer agar-based direct phenotypic drug-susceptibility testing on sputum in Eswatini rapidly detects Mycobacterium tuberculosis growth and rifampicin resistance, otherwise missed by WHO endorsed diagnostic tests.
Antimicrob Agents Chemother. 2021 Mar 15. pii: AAC.02263.
PubMed Abstract available

WEI Y, Sluis-Cremer N
Mutations in the HIV-1 3'-Polypurine Tract and Integrase Strand-Transfer Inhibitor Resistance.
Antimicrob Agents Chemother. 2021 Mar 15. pii: AAC.02432.
PubMed Abstract available

February 2021

ATTERBY C, Nykvist M, Lustig U, Andersson DI, et al
Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

FANG Y, Kirsch JR, Li L, Brooks SA, et al
Deimmunized Lysostaphin Synergizes with Small-Molecule Chemotherapies and Resensitizes Methicillin-Resistant Staphylococcus aureus to beta-Lactam Antibiotics.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

WANG G, Brunel JM, Bolla JM, Van Bambeke F, et al
The Polyaminoisoprenyl Potentiator NV716 Revives Old Disused Antibiotics against Intracellular Forms of Infection by Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

January 2021

SMITH NM, Ang A, Tan F, Macias K, et al
Interaction of Staphylococcus aureus and Acinetobacter baumannii during in vitro beta-lactam exposure.
Antimicrob Agents Chemother. 2021 Jan 25. pii: AAC.02414.
PubMed Abstract available

OLIVER MB, Fong K, Certain L, Spivak ES, et al
Validation of a Community-Acquired Pneumonia Score To Improve Empiric Antibiotic Selection at an Academic Medical Center.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

YANG J, Liu L, Feng Y, He D, et al
Potential Mobilization of mcr-10 by an Integrative Mobile Element via Site-Specific Recombination in Cronobacter sakazakii.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

KHABTHANI S, Hamel M, Baron SA, Diene SM, et al
fosM, a New Family of Fosfomycin Resistance Genes Identified in Bacterial Species Isolated from Human Microbiota.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

PYBUS CA, Felder-Scott C, Obuekwe V, Greenberg DE, et al
Cefiderocol Retains Antibiofilm Activity in Multidrug-Resistant Gram-Negative Pathogens.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

YIN Y, Zhang H, Zhang Y, Hu C, et al
Fungal Zn(II)2Cys6 Transcription Factor ADS-1 Regulates Drug Efflux and Ergosterol Metabolism under Antifungal Azole Stress.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

MOTOS A, Li Bassi G, Pagliara F, Fernandez-Barat L, et al
Short-Term Effects of Appropriate Empirical Antimicrobial Treatment with Ceftolozane/Tazobactam in a Swine Model of Nosocomial Pneumonia.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

BURNARD D, Robertson G, Henderson A, Falconer C, et al
Burkholderia pseudomallei Clinical Isolates Are Highly Susceptible In Vitro to Cefiderocol, a Siderophore Cephalosporin.
Antimicrob Agents Chemother. 2021;65.
PubMed Abstract available

PRATER AG, Mehta HH, Beabout K, Supandy A, et al
Daptomycin resistance in Enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway.
Antimicrob Agents Chemother. 2021 Jan 19. pii: AAC.01317.
PubMed Abstract available

PFALLER MA, Messer SA, Deshpande LM, Rhomberg PR, et al
Evaluation of Synergistic Activity of Isavuconazole or Voriconazole plus Anidulafungin and the Occurrence and Genetic Characterisation of Candida auris Detected in a Surveillance Program.
Antimicrob Agents Chemother. 2021 Jan 11. pii: AAC.02031.
PubMed Abstract available

CAZER CL, Westblade LF, Simon MS, Magleby R, et al
Analysis of multidrug resistance in Staphylococcus aureus with a machine learning generated antibiogram.
Antimicrob Agents Chemother. 2021 Jan 11. pii: AAC.02132.
PubMed Abstract available

DU W, Zhai P, Wang T, Bromley MJ, et al
The C2H2 Transcription Factor SltA Contributes to Azole Resistance by Coregulating the Expression of the Drug Target Erg11A and the Drug Efflux Pump Mdr1 in Aspergillus fumigatus.
Antimicrob Agents Chemother. 2021 Jan 11. pii: AAC.01839.
PubMed Abstract available

December 2020

CHU S, Long L, Sherif R, McCormick TS, et al
A second generation fungerp analog SCY-247, shows potent in vitro activity against Candida auris and other clinically relevant fungal isolates.
Antimicrob Agents Chemother. 2020 Dec 14. pii: AAC.01988.
PubMed Abstract available

MARGOT N, Ram R, Rhee M, Callebaut C, et al
Absence of Lenacapavir (GS-6207) Phenotypic Resistance in HIV Gag Cleavage Site Mutants and in Isolates with Resistance to Existing Drug Classes.
Antimicrob Agents Chemother. 2020 Dec 7. pii: AAC.02057.
PubMed Abstract available

November 2020

VIJAY S, Nhung HN, Bao NLH, Thu DDA, et al
Most-probable number based minimum duration of killing assay for determining the spectrum of rifampicin susceptibility in clinical M. tuberculosis isolates.
Antimicrob Agents Chemother. 2020 Nov 30. pii: AAC.01439.
PubMed Abstract available

ASADZADEH M, Dashti M, Ahmad S, Alfouzan W, et al
Whole genome and targeted-amplicon sequencing of fluconazole-susceptible and -resistant Candida parapsilosis isolates from Kuwait reveals a previously undescribed N1132D polymorphism in CDR1.
Antimicrob Agents Chemother. 2020 Nov 30. pii: AAC.01633.
PubMed Abstract available

PHAM CD, Nash E, Liu H, Schmerer MW, et al
Atypical Mutation in Neisseria gonorrhoeae 23S rRNA Associated with High-Level Azithromycin Resistance.
Antimicrob Agents Chemother. 2020 Nov 2. pii: AAC.00885.
PubMed Abstract available

October 2020

BING J, Hu T, Zheng Q, Munoz JF, et al
Experimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris.
Antimicrob Agents Chemother. 2020 Oct 19. pii: AAC.01466.
PubMed Abstract available

NAVARRO-RODRIGUEZ P, Lopez-Fernandez L, Martin-Vicente A, Guarro J, et al
ERG11 polymorphism in voriconazole-resistant Candida tropicalis. Weak role of ERG11 expression, ergosterol content and membrane permeability.
Antimicrob Agents Chemother. 2020 Oct 19. pii: AAC.00325.
PubMed Abstract available

SERRANO-LOBO J, Gomez A, Sanchez-Yebra W, Fajardo M, et al
Azole and amphotericin B minimum inhibitory concentrations against Aspergillus fumigatus: high agreement between spectrophotometric and visual readings using the EUCAST 9.3.2 procedure.
Antimicrob Agents Chemother. 2020 Oct 5. pii: AAC.01693.
PubMed Abstract available

ZHOU YF, Liu P, Dai SH, Sun J, et al
Activity of tigecycline or colistin in combination with zidovudine against Escherichia coli harboring tet(X) and mcr-1.
Antimicrob Agents Chemother. 2020 Oct 5. pii: AAC.01172.
PubMed Abstract available

September 2020

CACACI M, Menchinelli G, Torelli R, Sanglard D, et al
Fenticonazole against Fluconazole-Resistant Candida Species: New In Vitro Activity Data.
Antimicrob Agents Chemother. 2020 Sep 28. pii: AAC.01459.
PubMed Abstract available

LIM HJ, Shin JH, Kim MN, Yong D, et al
Evaluation of Two Commercial Broth Microdilution Methods Using Different Interpretive Criteria for the Detection of Molecular Mechanisms of Acquired Azole and Echinocandin Resistance in Four Common Candida Species.
Antimicrob Agents Chemother. 2020 Sep 8. pii: AAC.00740.
PubMed Abstract available

August 2020

STAPLETON AE, Wagenlehner FME, Mulgirigama A, Twynholm M, et al
E. coli Resistance to Fluoroquinolones in Community-Acquired Uncomplicated Urinary Tract Infection In Women: A Systematic Review.
Antimicrob Agents Chemother. 2020 Aug 3. pii: AAC.00862.
PubMed Abstract available

July 2020

CAO D, Wu R, Dong S, Wang F, et al
Azole resistance in environmental Aspergillus fumigatus isolates from China: A five-year survey from 2014 to 2018.
Antimicrob Agents Chemother. 2020 Jul 27. pii: AAC.00904.
PubMed Abstract available

ARASTEHFAR A, Daneshnia F, Hilmioglu-Polat S, Fang W, et al
First report of candidemia clonal outbreak caused by emerging fluconazole-resistant Candida parapsilosis isolates harboring Y132F and/or Y132F+K143R in Turkey.
Antimicrob Agents Chemother. 2020 Jul 20. pii: AAC.01001.
PubMed Abstract available

ROUNDTREE MT, Juvvadi PR, Shwab EK, Cole DC, et al
Aspergillus fumigatus Cyp51A and Cyp51B Proteins are Compensatory in Function and Localize Differentially in Response to Antifungals and Cell Wall Inhibitors.
Antimicrob Agents Chemother. 2020 Jul 13. pii: AAC.00735.
PubMed Abstract available

June 2020

SMITH SJ, Zhao XZ, Passos DO, Lyumkis D, et al
HIV-1 Integrase Inhibitors that are active against Drug-Resistant Integrase Mutants.
Antimicrob Agents Chemother. 2020 Jun 29. pii: AAC.00611.
PubMed Abstract available

HAO S, Abdelghany M, Lyden A, Sit R, et al
Genomic Profiling of Evolving Daptomycin Resistance in a Patient with Recurrent Staphylococcus argenteus Sepsis.
Antimicrob Agents Chemother. 2020 Jun 29. pii: AAC.00961.
PubMed Abstract available

SAFI H, Lingaraju S, Ma S, Husain S, et al
Rapidly-correcting Frameshift Mutations in the Mycobacterium tuberculosis orn Gene Produce Reversible Ethambutol Resistance and Small Colony Variant Morphology.
Antimicrob Agents Chemother. 2020 Jun 22. pii: AAC.00213.
PubMed Abstract available

KHALIFA HO, Arai T, Majima H, Watanabe A, et al
Genetic Basis of Azole and Echinocandin Resistance in Clinical Candida glabrata in Japan.
Antimicrob Agents Chemother. 2020 Jun 22. pii: AAC.00783.
PubMed Abstract available

PAIS P, California R, Galocha M, Viana R, et al
Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance Through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability.
Antimicrob Agents Chemother. 2020 Jun 22. pii: AAC.00554.
PubMed Abstract available

COHEN KA, Stott KE, Munsamy V, Manson AL, et al
Evidence for expanding the role of streptomycin in the management of drug-resistant M. tuberculosis.
Antimicrob Agents Chemother. 2020 Jun 15. pii: AAC.00860.
PubMed Abstract available

May 2020

ZILBERBERG MD, Nathanson BH, Sulham K, Shorr AF, et al
Antimicrobial susceptibility and cross-resistance patterns among common complicated urinary tract infections in US hospitals, 2013-2018.
Antimicrob Agents Chemother. 2020 May 18. pii: AAC.00346.
PubMed Abstract available

MACEDO D, Brito Devoto T, Pola S, Finquelievich JL, et al
A novel combination of CYP51A mutations confers pan-azole resistance in Aspergillus fumigatus.
Antimicrob Agents Chemother. 2020 May 18. pii: AAC.02501.
PubMed Abstract available

ADAMS SE, Lugovtsev VY, Kan A, Bovin NV, et al
Laninamivir-Interferon-lambda1 Combination Treatment Promotes Resistance by Influenza A Virus More Rapidly Than Laninamivir Alone.
Antimicrob Agents Chemother. 2020 May 11. pii: AAC.00301.
PubMed Abstract available

April 2020

KIM D, Yoon EJ, Hong JS, Lee H, et al
Impact of vanA-positive Enterococcus faecium exhibiting diverse susceptibility phenotypes to glycopeptides on 30-day mortality of patients with a bloodstream infection.
Antimicrob Agents Chemother. 2020 Apr 27. pii: AAC.02180.
PubMed Abstract available

ENDIMIANI A, Bernasconi OJ, Budel T, Campos-Madueno EI, et al
Whole-Genome Characterization of a Shewanella algae Strain Coharboring bla CTX-M-15 and armA Genes on a Novel IncC Plasmid.
Antimicrob Agents Chemother. 2020;64.
PubMed

MATSUO N, Nonogaki R, Hayashi M, Wachino JI, et al
Characterization of bla CTX-M-27/F1:A2:B20 Plasmids Harbored by Escherichia coli Sequence Type 131 Sublineage C1/H30R Isolates Spreading among Elderly Japanese in Nonacute-Care Settings.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

HAYASHI M, Nishiyama A, Kitamoto R, Tateishi Y, et al
Adduct Formation of Delamanid with NAD in Mycobacteria.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

LIN YT, Cheng YH, Chuang C, Chou SH, et al
Molecular and Clinical Characterization of Multidrug-Resistant and Hypervirulent Klebsiella pneumoniae Strains from Liver Abscess in Taiwan.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

JACOBS MR, Good CE, Hujer AM, Abdelhamed AM, et al
ARGONAUT II Study of the In Vitro Activity of Plazomicin against Carbapenemase-Producing Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

PALWE S, Veeraraghavan B, Periasamy H, Khobragade K, et al
Unorthodox Parenteral beta-Lactam and beta-Lactamase Inhibitor Combinations: Flouting Antimicrobial Stewardship and Compromising Patient Care.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

ESHAGHI A, Zittermann S, Bharat A, Mulvey MR, et al
Importation of Extensively Drug-Resistant Salmonella enterica Serovar Typhi Cases in Ontario, Canada.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

KIEFFER N, Poirel L, Mueller L, Mancini S, et al
ISEcp1-Mediated Transposition Leads to Fosfomycin and Broad-Spectrum Cephalosporin Resistance in Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

STOESSER N, Phan HTT, Seale AC, Aiken Z, et al
Genomic Epidemiology of Complex, Multispecies, Plasmid-Borne bla KPC Carbapenemase in Enterobacterales in the United Kingdom from 2009 to 2014.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

CASTANHEIRA M, Sader HS, Mendes RE, Jones RN, et al
Activity of Plazomicin Tested against Enterobacterales Isolates Collected from U.S. Hospitals in 2016-2017: Effect of Different Breakpoint Criteria on Susceptibility Rates among Aminoglycosides.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

SADER HS, Carvalhaes CG, Duncan LR, Shortridge D, et al
Antimicrobial Activity of Ceftolozane-Tazobactam and Comparators against Clinical Isolates of Haemophilus influenzae from the United States and Europe.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

KARKI P, Mohiuddin SG, Kavousi P, Orman MA, et al
Investigating the Effects of Osmolytes and Environmental pH on Bacterial Persisters.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

KAYE KS, Boucher HW, Brown ML, Aggrey A, et al
Comparison of Treatment Outcomes between Analysis Populations in the RESTORE-IMI 1 Phase 3 Trial of Imipenem-Cilastatin-Relebactam versus Colistin plus Imipenem-Cilastatin in Patients with Imipenem-Nonsusceptible Bacterial Infections.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

SCHMERER MW, Abrams AJ, Seby S, Thomas JC 4th, et al
Genomic Characterization of Neisseria gonorrhoeae Strains from 2016 U.S. Sentinel Surveillance Displaying Reduced Susceptibility to Azithromycin.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

OUESLATI S, Retailleau P, Marchini L, Berthault C, et al
Role of Arginine 214 in the Substrate Specificity of OXA-48.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

PFALLER MA, Huband MD, Shortridge D, Flamm RK, et al
Surveillance of Omadacycline Activity Tested against Clinical Isolates from the United States and Europe: Report from the SENTRY Antimicrobial Surveillance Program, 2016 to 2018.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

HUBAND MD, Mendes RE, Pfaller MA, Lindley JM, et al
In Vitro Activity of KBP-7072, a Novel Third-Generation Tetracycline, against 531 Recent Geographically Diverse and Molecularly Characterized Acinetobacter baumannii Species Complex Isolates.
Antimicrob Agents Chemother. 2020;64.
PubMed Abstract available

ZHAO L, Yan Y, Dai Q, Li X, et al
Development of Novel Anti-influenza Thiazolides with Relatively Broad-spectrum Antiviral Potentials.
Antimicrob Agents Chemother. 2020 Apr 20. pii: AAC.00222.
PubMed Abstract available

ALMEIDA LM, Lebreton F, Gaca A, Bispo PM, et al
Transferable Resistance Gene optrA in Enterococcus faecalis from Swine in Brazil.
Antimicrob Agents Chemother. 2020 Apr 6. pii: AAC.00142.
PubMed Abstract available

BROWN MM, Kwiecinski JM, Mejia Cruz L, Shahbandi A, et al
Novel peptide from commensal Staphylococcus simulans blocks MRSA quorum sensing and protects host skin from damage.
Antimicrob Agents Chemother. 2020 Apr 6. pii: AAC.00172.
PubMed Abstract available

March 2020

LISTON SD, Whitesell L, Kapoor M, Shaw KJ, et al
Enhanced efflux pump expression in Candida mutants results in decreased manogepix susceptibility.
Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.00261.
PubMed Abstract available

ENKIRCH T, Werngren J, Groenheit R, Alm E, et al
Systematic review of whole genome sequencing data to predict phenotypic drug resistance and susceptibility in Swedish Mycobacterium tuberculosis isolates 2016-2018.
Antimicrob Agents Chemother. 2020 Mar 2. pii: AAC.02550.
PubMed Abstract available

SINGH KV, Arias CA, Murray BE
Tedizolid as step-down therapy following daptomycin versus continuation of daptomycin against enterococci and Staphylococcus aureus (MRSA/VRSA) in a rat endocarditis model.
Antimicrob Agents Chemother. 2020 Mar 2. pii: AAC.02303.
PubMed Abstract available

February 2020

CARVAJAL LP, Rincon S, Echeverri AM, Porras J, et al
Novel Insights Into The Classification of Staphylococcal beta-Lactamases In Relation To The Cefazolin Inoculum Effect.
Antimicrob Agents Chemother. 2020 Feb 18. pii: AAC.02511.
PubMed Abstract available

GENGENBACHER M, Zimmerman MD, Sarathy JP, Kaya F, et al
Tissue distribution of doxycycline in animal models of tuberculosis.
Antimicrob Agents Chemother. 2020 Feb 10. pii: AAC.02479.
PubMed Abstract available

Thank you for your interest in scientific medicine.

AMEDEO Drug Resistance is free of charge.