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Diabetes

Free Subscription Articles published in J Clin Invest Retrieve available abstracts of 50 articles: HTML format

Single Articles

March 2024
1. DI GIUSEPPE G, Soldovieri L, Ciccarelli G, Ferraro PM, et al
   Reduced incretin effect precedes diabetes development following duodenopancreatectomy in subjects without diabetes.
   J Clin Invest. 2024 Mar 12:e175133. doi: 10.1172/JCI175133.
   PubMed    
   
   
   
2. DEFRONZO RA
   SGLT2 inhibitors: cardiorenal metabolic drugs for the ages.
   J Clin Invest. 2024;134:e177625.
   PubMed    
   
   
   February 2024
3. BERGMAN RN
   Pancreatic beta cell function versus insulin resistance: application of the hyperbolic law of glucose tolerance.
   J Clin Invest. 2024;134:e176738.
   PubMed    
   
   
   January 2024
4. DRUCKER DJ
   The GLP-1 journey: from discovery science to therapeutic impact.
   J Clin Invest. 2024;134:e175634.
   PubMed    
   
   
   
5. HAIDER N, Kahn CR
   Interactions among insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts.
   J Clin Invest. 2024;134:e172333.
   PubMed     Abstract available
   
   
   November 2023
6. GOVINDARAJAH V, Sakabe M, Good S, Solomon M, et al
   Gestational diabetes in mice induces hematopoietic memory that impacts the long-term health of the offspring.
   J Clin Invest. 2023 Nov 21:e169730. doi: 10.1172/JCI169730.
   PubMed     Abstract available
   
   
   
7. WELCH AA, Farahani RA, Egan AM, Laurenti MC, et al
   Glucagon-like peptide-1 receptor blockade impairs islet secretion and glucose metabolism in humans.
   J Clin Invest. 2023;133:e173495.
   PubMed     Abstract available
   
   
   October 2023
8. DREXLER Y, Fornoni A
   Adenine crosses the biomarker bridge: from 'omics to treatment in diabetic kidney disease.
   J Clin Invest. 2023;133:e174015.
   PubMed     Abstract available
   
   
   
9. BLOT G, Karadayi R, Przegralek L, Sartoris TM, et al
   Perilipin 2-positive mononuclear phagocytes accumulate in the diabetic retina and promote PPARgamma-dependent vasodegeneration.
   J Clin Invest. 2023;133:e161348.
   PubMed     Abstract available
   
   
   
10. ZHOU C, She X, Gu C, Hu Y, et al
    FTO fuels diabetes-induced vascular endothelial dysfunction associated with inflammation by erasing m6A methylation of TNIP1.
    J Clin Invest. 2023;133:e160517.
    PubMed     Abstract available
    
    
    
11. GOU Y, Schwartz MW
    How should we think about the unprecedented weight loss efficacy of incretin-mimetic drugs?
    J Clin Invest. 2023;133:e174597.
    PubMed    
    
    
    September 2023
12. STAMATERIS RE, Landa-Galvan HV, Sharma RB, Darko C, et al
    Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting beta cell differentiation.
    J Clin Invest. 2023;133:e166490.
    PubMed     Abstract available
    
    
    August 2023
13. SHARMA K, Zhang G, Hansen J, Bjornstad P, et al
    Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients.
    J Clin Invest. 2023 Aug 24:e170341. doi: 10.1172/JCI170341.
    PubMed     Abstract available
    
    
    
14. SPANIER JA, Fung V, Wardell CM, Alkhatib MH, et al
    Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes in mice.
    J Clin Invest. 2023 Aug 10:e168601. doi: 10.1172/JCI168601.
    PubMed     Abstract available
    
    
    July 2023
15. SATO M, Neufeld EB, Playford MP, Lei Y, et al
    Cell-free high-density lipoprotein-specific phospholipid efflux assay predicts incident cardiovascular disease.
    J Clin Invest. 2023 Jul 20:e165370. doi: 10.1172/JCI165370.
    PubMed     Abstract available
    
    
    
16. BAHN YJ, Yadav H, Piaggi P, Abel BS, et al
    CDK4-E2F3 signals enhance oxidative skeletal muscle fiber numbers and function to affect myogenesis and metabolism.
    J Clin Invest. 2023;133:e162479.
    PubMed     Abstract available
    
    
    June 2023
17. SPINELLI R, Baboota RK, Gogg S, Beguinot F, et al
    Increased cell senescence in human metabolic disorders.
    J Clin Invest. 2023;133:e169922.
    PubMed     Abstract available
    
    
    May 2023
18. ZHANG J, Sharma D, Dinabandhu A, Sanchez J, et al
    Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice.
    J Clin Invest. 2023 May 25:e163290. doi: 10.1172/JCI163290.
    PubMed     Abstract available
    
    
    
19. EADE KT, Ansell BRE, Giles S, Fallon R, et al
    iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function.
    J Clin Invest. 2023;133:e163771.
    PubMed     Abstract available
    
    
    April 2023
20. WORTHAM M, Liu F, Harrington AR, Fleischman JY, et al
    Nutrient regulation of the islet epigenome controls adaptive insulin secretion.
    J Clin Invest. 2023;133:e165208.
    PubMed     Abstract available
    
    
    March 2023
21. ALBARIQI MM, Versteeg S, Brakkee EM, Coert JH, et al
    Human IAPP is a contributor to painful diabetic peripheral neuropathy.
    J Clin Invest. 2023 Mar 14:e156993. doi: 10.1172/JCI156993.
    PubMed     Abstract available
    
    
    
22. TUTTLE KR
    Digging deep into cells to find mechanisms of kidney protection by SGLT2 inhibitors.
    J Clin Invest. 2023;133:e167700.
    PubMed     Abstract available
    
    
    February 2023
23. MOHANDES S, Doke T, Hu H, Mukhi D, et al
    Molecular pathways that drive diabetic kidney disease.
    J Clin Invest. 2023;133:e165654.
    PubMed     Abstract available
    
    
    
24. KIM MH, Li Y, Zheng Q, Jiang L, et al
    LepRb+ cell-specific deletion of Slug mitigates obesity and nonalcoholic fatty liver disease in mice.
    J Clin Invest. 2023;133:e156722.
    PubMed     Abstract available
    
    
    
25. BASS J, Tschop MH, Beutler LR
    Dual gut hormone receptor agonists for diabetes and obesity.
    J Clin Invest. 2023;133:e167952.
    PubMed    
    
    
    
26. KALLAPUR A, Sallam T
    Endothelial cells LEENE on noncoding RNAs in diabetic vasculopathy.
    J Clin Invest. 2023;133:e167047.
    PubMed     Abstract available
    
    
    January 2023
27. BACOS K, Perfilyev A, Karagiannopoulos A, Cowan E, et al
    Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets.
    J Clin Invest. 2023 Jan 19:e163612. doi: 10.1172/JCI163612.
    PubMed     Abstract available
    
    
    
28. SCHAUB JA, AlAkwaa FM, McCown PJ, Naik AS, et al
    SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth onset type 2 diabetes.
    J Clin Invest. 2023 Jan 13:e164486. doi: 10.1172/JCI164486.
    PubMed     Abstract available
    
    
    
29. KHURANA I, Kaipananickal H, Maxwell S, Birkelund S, et al
    Reduced methylation corresponds with diabetic nephropathy risk in type 1 diabetes reduced methylation corresponds with diabetic nephropathy risk.
    J Clin Invest. 2023 Jan 12:e160959. doi: 10.1172/JCI160959.
    PubMed     Abstract available
    
    
    December 2022
30. TANG X, Luo Y, Yuan D, Calandrelli R, et al
    Long non-coding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models.
    J Clin Invest. 2022 Dec 13:e161759. doi: 10.1172/JCI161759.
    PubMed     Abstract available
    
    
    October 2022
31. DU W, Wang J, Kuo T, Wang L, et al
    Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals.
    J Clin Invest. 2022 Oct 25. pii: 162720. doi: 10.1172/JCI162720.
    PubMed     Abstract available
    
    
    
32. WARNCKE K, Weiss A, Achenbach P, von dem Berge T, et al
    Elevations in blood glucose before and after the appearance of islet autoantibodies in children.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
33. DONATH MY
    Type 1 diabetes: what is the role of autoimmunity in beta cell death?
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
34. PORRETT PM, Locke JE
    A roadmap for human trials of xenotransplantation.
    J Clin Invest. 2022;132.
    PubMed    
    
    
    August 2022
35. WANG P, Karakose E, Argmann C, Wang H, et al
    Disrupting the DREAM complex enables proliferation of adult human pancreatic beta cells.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    June 2022
36. DOLIBA NM, Rozo AV, Roman J, Qin W, et al
    alpha Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    May 2022
37. GUZMAN S, Dragan M, Kwon H, de Oliveira V, et al
    Targeting hepatic kisspeptin receptor ameliorates nonalcoholic fatty liver disease in a mouse model.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
38. MILLER B, Kim SJ, Kumagai H, Yen K, et al
    Mitochondria-derived peptides in aging and healthspan.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    March 2022
39. BOUTAGY NE, Singh AK, Sessa WC
    Targeting the vasculature in cardiometabolic disease.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
40. TRAVERS JG, Tharp CA, Rubino M, McKinsey TA, et al
    Therapeutic targets for cardiac fibrosis: from old school to next-gen.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    February 2022
41. BUTLER PC, Gale EA
    Reversing type 1 diabetes with stem cell-derived islets: a step closer to the dream?
    J Clin Invest. 2022;132.
    PubMed    
    
    
    January 2022
42. ANDERSEN RC, Schmidt JH, Rombach J, Lycas MD, et al
    Coding variants identified in diabetic patients alter PICK1 BAR domain function in insulin granule biogenesis.
    J Clin Invest. 2022 Jan 25. pii: 144904. doi: 10.1172/JCI144904.
    PubMed     Abstract available
    
    
    December 2021
43. SON J, Ding H, Farb TB, Efanov AM, et al
    BACH2 inhibition reverses beta cell failure in type 2 diabetes models.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
44. IMAI Y
    Deciphering regulatory protein activity in human pancreatic islets via reverse engineering of single-cell sequencing data.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    November 2021
45. PASTAR I, Sawaya AP, Marjanovic J, Burgess JL, et al
    Intracellular Staphylococcus aureus triggers pyroptosis and contributes to inhibition of healing due to Perforin-2 suppression.
    J Clin Invest. 2021 Nov 2. pii: 133727. doi: 10.1172/JCI133727.
    PubMed     Abstract available
    
    
    
46. TOKARZ VL, Delgado-Olguin P, Klip A
    Deprogram and reprogram to solve the riddle of insulin resistance.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    September 2021
47. BHARDWAJ G, Penniman CM, Jena J, Suarez Beltran PA, et al
    Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
48. BROWN MR, Holmes H, Rakshit K, Javeed N, et al
    Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic beta cell function in type 2 diabetes.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    June 2021
49. SINGH AK, Netea MG, Bishai WR
    BCG turns 100: its nontraditional uses against viruses, cancer, and immunologic diseases.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    May 2021
50. LEE SJ
    Targeting the myostatin signaling pathway to treat muscle loss and metabolic dysfunction.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    

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