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Articles published in J Clin Invest

Retrieve available abstracts of 25 articles:
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Single Articles


    January 2012
  1. UNGER RH , Cherrington AD
    Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover.
    J Clin Invest. 2012;122:4-12.
    PubMed     Text format     Related articles    Abstract available



    December 2011
  2. ZIOLKOWSKI AF , Popp SK, Freeman C, Parish CR, et al
    Heparan sulfate and heparanase play key roles in mouse beta cell survival and autoimmune diabetes.
    J Clin Invest. 2011 Dec 19. pii: 46177. doi: 10.1172/JCI46177.
    PubMed     Text format     Related articles    Abstract available



  3. COPPIETERS K , Amirian N, von Herrath M
    Intravital imaging of CTLs killing islet cells in diabetic mice.
    J Clin Invest. 2011 Dec 1. pii: 59285. doi: 10.1172/JCI59285.
    PubMed     Text format     Related articles    Abstract available



  4. KLEE P , Allagnat F, Pontes H, Cederroth M, et al
    Connexins protect mouse pancreatic beta cells against apoptosis.
    J Clin Invest. 2011;121:4870-9.
    PubMed     Text format     Related articles    Abstract available



    November 2011
  5. TANG WH , Stitham J, Gleim S, Di Febbo C, et al
    Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane.
    J Clin Invest. 2011;121:4462-76.
    PubMed     Text format     Related articles    Abstract available



  6. SCHENK S , McCurdy CE, Philp A, Chen MZ, et al
    Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.
    J Clin Invest. 2011;121:4281-8.
    PubMed     Text format     Related articles    Abstract available



    October 2011
  7. CHENG CF , Sahu D, Tsen F, Zhao Z, et al
    A fragment of secreted Hsp90alpha carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice.
    J Clin Invest. 2011 Oct 24. pii: 46475. doi: 10.1172/JCI46475.
    PubMed     Text format     Related articles    Abstract available



  8. LIU SM , Lee DH, Sullivan JM, Chung D, et al
    Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.
    J Clin Invest. 2011 Oct 24. pii: 46187. doi: 10.1172/JCI46187.
    PubMed     Text format     Related articles    Abstract available



    August 2011
  9. WEI FY , Suzuki T, Watanabe S, Kimura S, et al
    Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in mice.
    J Clin Invest. 2011 Aug 15. pii: 58056. doi: 10.1172/JCI58056.
    PubMed     Text format     Related articles    Abstract available



    July 2011
  10. TIANO JP , Delghingaro-Augusto V, Le May C, Liu S, et al
    Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents beta cell failure in rodent models of type 2 diabetes.
    J Clin Invest. 2011 Jul 11. pii: 44564. doi: 10.1172/JCI44564.
    PubMed     Text format     Related articles    Abstract available



  11. MONTANE J , Bischoff L, Soukhatcheva G, Dai DL, et al
    Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets.
    J Clin Invest. 2011 Jul 1. pii: 43048. doi: 10.1172/JCI43048.
    PubMed     Text format     Related articles    Abstract available



    June 2011
  12. SEINO S , Shibasaki T, Minami K
    Dynamics of insulin secretion and the clinical implications for obesity and diabetes.
    J Clin Invest. 2011;121:2118-25.
    PubMed     Text format     Related articles    Abstract available



  13. HUANG W , Ramsey KM, Marcheva B, Bass J, et al
    Circadian rhythms, sleep, and metabolism.
    J Clin Invest. 2011;121:2133-41.
    PubMed     Text format     Related articles    Abstract available



  14. GREENBERG AS , Coleman RA, Kraemer FB, McManaman JL, et al
    The role of lipid droplets in metabolic disease in rodents and humans.
    J Clin Invest. 2011;121:2102-10.
    PubMed     Text format     Related articles    Abstract available



    May 2011
  15. INOKI K , Mori H, Wang J, Suzuki T, et al
    mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
    J Clin Invest. 2011 May 23. pii: 44771. doi: 10.1172/JCI44771.
    PubMed     Text format     Related articles    Abstract available



  16. GODEL M , Hartleben B, Herbach N, Liu S, et al
    Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
    J Clin Invest. 2011 May 23. pii: 44774. doi: 10.1172/JCI44774.
    PubMed     Text format     Related articles    Abstract available



    April 2011
  17. VIRET C , Leung-Theung-Long S, Serre L, Lamare C, et al
    Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice.
    J Clin Invest. 2011 Apr 18. pii: 43314. doi: 10.1172/JCI43314.
    PubMed     Text format     Related articles    Abstract available



    March 2011
  18. MCCARTNEY SA , Vermi W, Lonardi S, Rossini C, et al
    RNA sensor-induced type I IFN prevents diabetes caused by a beta cell-tropic virus in mice.
    J Clin Invest. 2011 Mar 14. pii: 44005. doi: 10.1172/JCI44005.
    PubMed     Text format     Related articles    Abstract available



  19. RHEE EP , Cheng S, Larson MG, Walford GA, et al
    Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.
    J Clin Invest. 2011 Mar 14. pii: 44442. doi: 10.1172/JCI44442.
    PubMed     Text format     Related articles    Abstract available



    February 2011
  20. HUANG G , Ge G, Wang D, Gopalakrishnan B, et al
    alpha3(V) collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues.
    J Clin Invest. 2011;121:769-83.
    PubMed     Text format     Related articles    Abstract available



    January 2011
  21. CHARLES ED , Dustin LB
    Chemokine antagonism in chronic hepatitis C virus infection.
    J Clin Invest. 2011;121:25-7.
    PubMed     Text format     Related articles    Abstract available



    December 2010
  22. BADELL IR , Russell MC, Thompson PW, Turner AP, et al
    LFA-1-specific therapy prolongs allograft survival in rhesus macaques.
    J Clin Invest. 2010;120:4520-31.
    PubMed     Text format     Related articles    Abstract available



  23. BILATE AM , Lafaille JJ
    Can TNF-alpha boost regulatory T cells?
    J Clin Invest. 2010;120:4190-2.
    PubMed     Text format     Related articles    Abstract available



  24. RIVERA N , Ramnanan CJ, An Z, Farmer T, et al
    Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs.
    J Clin Invest. 2010;120:4425-35.
    PubMed     Text format     Related articles    Abstract available



  25. MORETH K , Brodbeck R, Babelova A, Gretz N, et al
    The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.
    J Clin Invest. 2010;120:4251-72.
    PubMed     Text format     Related articles    Abstract available



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