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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Colorectal Neoplasms

Free Subscription Articles published in J Clin Oncol Retrieve available abstracts of 145 articles: HTML format

Single Articles

July 2008
1. WOLPIN BM , Wei EK, Ng K, Meyerhardt JA, et al
   Prediagnostic plasma folate and the risk of death in patients with colorectal cancer.
   J Clin Oncol. 2008;26:3222-8.
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2. COHEN SJ , Punt CJ, Iannotti N, Saidman BH, et al
   Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer.
   J Clin Oncol. 2008;26:3213-21.
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   June 2008
3. NG K , Meyerhardt JA, Wu K, Feskanich D, et al
   Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer.
   J Clin Oncol. 2008;26:2984-91.
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4. ULRICH CM , Holmes RS
   Shedding light on colorectal cancer prognosis: vitamin d and beyond.
   J Clin Oncol. 2008;26:2937-9.
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5. BOMAN BM , Huang E
   Human colon cancer stem cells: a new paradigm in gastrointestinal oncology.
   J Clin Oncol. 2008;26:2828-38.
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6. D'ANGELICA M , Fong Y, DeMatteo RP, Jarnagin WR, et al
   Hepatic arterial infusion chemotherapy for metastases from colorectal cancer: is it really the end of an era?
   J Clin Oncol. 2008;26:2788-9.
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7. LIN WL , Lin WC, Yang JY, Chang YC, et al
   Fatal toxic epidermal necrolysis associated with cetuximab in a patient with colon cancer.
   J Clin Oncol. 2008;26:2779-80.
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8. BRAUN MS , Richman SD, Quirke P, Daly C, et al
   Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial.
   J Clin Oncol. 2008;26:2690-8.
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9. ALLEGRA CJ , Benedetti JK
   Don Quixote and the quest for personalized medicine.
   J Clin Oncol. 2008;26:2619-20.
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   May 2008
10. GARASSINO MC , Farina G, Rossi A, Martelli O, et al
    Should KRAS mutations be considered an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab?
    J Clin Oncol. 2008;26:2600.
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11. KEATING NL , Landrum MB, Klabunde CN, Fletcher RH, et al
    Adjuvant chemotherapy for stage III colon cancer: do physicians agree about the importance of patient age and comorbidity?
    J Clin Oncol. 2008;26:2532-7.
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12. POWER DG , Leonard GD
    Hepatic arterial infusion: a treatment at the "end of an era"?
    J Clin Oncol. 2008;26:2597-8.
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13. O'CONNELL MJ , Campbell ME, Goldberg RM, Grothey A, et al
    Survival following recurrence in stage II and III colon cancer: findings from the ACCENT data set.
    J Clin Oncol. 2008;26:2336-41.
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14. KOZUCH PS , Rocha-Lima CM, Dragovich T, Hochster H, et al
    Bortezomib with or without irinotecan in relapsed or refractory colorectal cancer: results from a randomized phase II study.
    J Clin Oncol. 2008;26:2320-6.
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15. KRISHNAN G , D'Silva K, Al-Janadi A
    Cetuximab-related tumor lysis syndrome in metastatic colon carcinoma.
    J Clin Oncol. 2008;26:2406-8.
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16. DE MAAT MF , van de Velde CJ, van der Werff MP, Putter H, et al
    Quantitative analysis of methylation of genomic loci in early-stage rectal cancer predicts distant recurrence.
    J Clin Oncol. 2008;26:2327-35.
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17. CASSIDY J , Schmoll HJ, Van Cutsem E
    Re: Should capecitabine replace infusional fluorouracil and leucovorin when combined with oxaliplatin in metastatic colorectal cancer?
    J Clin Oncol. 2008;26:2226-7.
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18. CHU E , Cartwright TH
    Pharmacoeconomic benefits of capecitabine-based chemotherapy in metastatic colorectal cancer.
    J Clin Oncol. 2008;26:2224-6.
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19. CESCON DW , Page AV, Richardson S, Moore MJ, et al
    Invasive pulmonary aspergillosis associated with marijuana use in a man with colorectal cancer.
    J Clin Oncol. 2008;26:2214-5.
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20. GAMELIN E , Delva R, Jacob J, Merrouche Y, et al
    Individual fluorouracil dose adjustment based on pharmacokinetic follow-up compared with conventional dosage: results of a multicenter randomized trial of patients with metastatic colorectal cancer.
    J Clin Oncol. 2008;26:2099-105.
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21. BLUMENTHAL GM , Dennis PA
    Germline PTEN mutations as a cause of early-onset endometrial cancer.
    J Clin Oncol. 2008;26:2234.
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22. PESTALOZZI BC , Gruttadauria S, Clavien PA
    Hepatic arterial infusion: the beginning of the combination era.
    J Clin Oncol. 2008;26:2231-2.
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23. DE REYNIES A , Boige V, Milano G, Faivre J, et al
    KRAS mutation signature in colorectal tumors significantly overlaps with the cetuximab response signature.
    J Clin Oncol. 2008;26:2228-30.
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24. BLANCHARD CM , Courneya KS, Stein K
    Cancer survivors' adherence to lifestyle behavior recommendations and associations with health-related quality of life: results from the American Cancer Society's SCS-II.
    J Clin Oncol. 2008;26:2198-204.
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25. HALLER DG , Cassidy J, Clarke SJ, Cunningham D, et al
    Potential regional differences for the tolerability profiles of fluoropyrimidines.
    J Clin Oncol. 2008;26:2118-23.
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26. WALKO CM , McLeod HL
    Will we ever be ready for blood level-guided therapy?
    J Clin Oncol. 2008;26:2078-9.
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27. LEIBOLD T , Shia J, Ruo L, Minsky BD, et al
    Prognostic implications of the distribution of lymph node metastases in rectal cancer after neoadjuvant chemoradiotherapy.
    J Clin Oncol. 2008;26:2106-11.
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    April 2008
28. OEHLER-JANNE C , Huguet F, Provencher S, Seifert B, et al
    HIV-Specific Differences in Outcome of Squamous Cell Carcinoma of the Anal Canal: A Multicentric Cohort Study of HIV-Positive Patients Receiving Highly Active Antiretroviral Therapy.
    J Clin Oncol. 2008;.
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29. EFFICACE F , Innominato PF, Bjarnason G, Coens C, et al
    Validation of patient's self-reported social functioning as an independent prognostic factor for survival in metastatic colorectal cancer patients: results of an international study by the Chronotherapy Group of the European Organisation for Research and
    J Clin Oncol. 2008;26:2020-6.
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30. SALTZ LB , Clarke S, Diaz-Rubio E, Scheithauer W, et al
    Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study.
    J Clin Oncol. 2008;26:2013-9.
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31. CASSIDY J , Clarke S, Diaz-Rubio E, Scheithauer W, et al
    Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer.
    J Clin Oncol. 2008;26:2006-12.
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32. KOPETZ S , Overman M, Chang DZ, Glover KY, et al
    Systematic survey of therapeutic trials for metastatic colorectal cancer: room for improvement in the critical pathway.
    J Clin Oncol. 2008;26:2000-5.
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33. HODI FS , Friedlander P, Corless CL, Heinrich MC, et al
    Major response to imatinib mesylate in KIT-mutated melanoma.
    J Clin Oncol. 2008;26:2046-51.
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34. BENSON AB 3RD
    From silos to a critical path of new agent development: a paradigm to revolutionize clinical research.
    J Clin Oncol. 2008;26:1924-5.
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35. PUNT CJ , Koopman M
    Capecitabine and irinotecan as first-line treatment of advanced colorectal cancer.
    J Clin Oncol. 2008;26:1907-8.
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36. GRUENBERGER B , Tamandl D, Schueller J, Scheithauer W, et al
    Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer.
    J Clin Oncol. 2008;26:1830-5.
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37. BILCHIK AJ , Hecht JR
    Perioperative risks of bevacizumab and other biologic agents for hepatectomy: theoretical or evidence based?
    J Clin Oncol. 2008;26:1786-8.
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38. SOBRERO AF , Maurel J, Fehrenbacher L, Scheithauer W, et al
    EPIC: Phase III Trial of Cetuximab Plus Irinotecan After Fluoropyrimidine and Oxaliplatin Failure in Patients With Metastatic Colorectal Cancer.
    J Clin Oncol. 2008;.
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39. CHAN CC , Tan A, Salman H
    Colon cancer 15 years after ureterosigmoidostomy.
    J Clin Oncol. 2008;26:1755-7.
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40. ADAM R , Wicherts DA, de Haas RJ, Aloia T, et al
    Complete pathologic response after preoperative chemotherapy for colorectal liver metastases: myth or reality?
    J Clin Oncol. 2008;26:1635-41.
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    March 2008
41. FOLPRECHT G , Seymour MT, Saltz L, Douillard JY, et al
    Irinotecan/fluorouracil combination in first-line therapy of older and younger patients with metastatic colorectal cancer: combined analysis of 2,691 patients in randomized controlled trials.
    J Clin Oncol. 2008;26:1443-51.
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42. GRAZIANO F , Ruzzo A, Loupakis F, Canestrari E, et al
    Pharmacogenetic profiling for cetuximab plus irinotecan therapy in patients with refractory advanced colorectal cancer.
    J Clin Oncol. 2008;26:1427-34.
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43. OWZAR K
    Alternate statistical tools and limitations in genetic marker association studies in single-arm drug cancer trials.
    J Clin Oncol. 2008;26:1400-1.
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44. BRANDI G , Pantaleo MA, Biasco G, Paterini P, et al
    Activated NF-kB in colorectal cancer: predictive or prognostic factor?
    J Clin Oncol. 2008;26:1388-9.
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45. ZALCBERG JR , Rosen LS, Abdi E, Davis ID, et al
    Role of palifermin in fluorouracil-based therapy for metastatic colorectal cancer.
    J Clin Oncol. 2008;26:1386-7.
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46. BALDUCCI L , Tam-McDevitt J, Hauser R, Simon J, et al
    Long overdue: phase II studies in older cancer patients: where does the FDA stand?
    J Clin Oncol. 2008;26:1387-88.
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47. AMADO RG , Wolf M, Peeters M, Van Cutsem E, et al
    Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer.
    J Clin Oncol. 2008;.
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48. SNYDER CF , Earle CC, Herbert RJ, Neville BA, et al
    Preventive care for colorectal cancer survivors: a 5-year longitudinal study.
    J Clin Oncol. 2008;26:1073-9.
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49. GAMELIN L , Boisdron-Celle M, Morel A, Poirier AL, et al
    Oxaliplatin-related neurotoxicity: interest of calcium-magnesium infusion and no impact on its efficacy.
    J Clin Oncol. 2008;26:1188-9.
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50. DE PALMA R , Liberati A, Ciccone G, Bandieri E, et al
    Developing clinical recommendations for breast, colorectal, and lung cancer adjuvant treatments using the GRADE system: a study from the Programma Ricerca e Innovazione Emilia Romagna Oncology Research Group.
    J Clin Oncol. 2008;26:1033-9.
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51. BROUWERS MC , Somerfield MR, Browman GP
    A for effort: learning from the application of the GRADE approach to cancer guideline development.
    J Clin Oncol. 2008;26:1025-6.
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    February 2008
52. ADENIS A , Mailliez A, Rigot JM, Gamelin L, et al
    Recurrent priapism related to oxaliplatin infusion.
    J Clin Oncol. 2008;26:1016-7.
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53. HADLEY DW , Jenkins JF, Steinberg SM, Liewehr D, et al
    Perceptions of cancer risks and predictors of colon and endometrial cancer screening in women undergoing genetic testing for Lynch syndrome.
    J Clin Oncol. 2008;26:948-54.
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54. FUCHS CS , Marshall J, Barrueco J
    Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: updated results from the BICC-C study.
    J Clin Oncol. 2008;26:689-90.
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55. VORDERMARK D
    Potential and limitations of intensity-modulated radiotherapy in anal cancer.
    J Clin Oncol. 2008;26:688.
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56. VELICER CM , Ulrich CM
    Vitamin and mineral supplement use among US adults after cancer diagnosis: a systematic review.
    J Clin Oncol. 2008;26:665-73.
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    January 2008
57. WEISER MR , Landmann RG, Kattan MW, Gonen M, et al
    Individualized prediction of colon cancer recurrence using a nomogram.
    J Clin Oncol. 2008;26:380-5.
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58. LIEVRE A , Bachet JB, Boige V, Cayre A, et al
    KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.
    J Clin Oncol. 2008;26:374-9.
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59. GELIBTER AJ , Zeuli M, Cognetti F, Di Segni S, et al
    Bevacizumab: one treatment for all the seasons?
    J Clin Oncol. 2008;26:511.
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60. FIETKAU R , Klautke G
    Adjuvant chemotherapy following neoadjuvant therapy of rectal cancer: the type of neoadjuvant therapy (chemoradiotherapy or radiotherapy) may be important for selection of patients.
    J Clin Oncol. 2008;26:507-8.
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61. CHIAO EY , Giordano TP, Richardson P, El-Serag HB, et al
    Human immunodeficiency virus-associated squamous cell cancer of the anus: epidemiology and outcomes in the highly active antiretroviral therapy era.
    J Clin Oncol. 2008;26:474-9.
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62. GUILLEM JG , Diaz-Gonzalez JA, Minsky BD, Valentini V, et al
    cT3N0 rectal cancer: potential overtreatment with preoperative chemoradiotherapy is warranted.
    J Clin Oncol. 2008;26:368-73.
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63. KACHNIC LA , Hong TS, Ryan DP
    Rectal cancer at the crossroads: the dilemma of clinically staged T3, N0, M0 disease.
    J Clin Oncol. 2008;26:350-1.
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64. GROTHEY A , Hedrick EE, Mass RD, Sarkar S, et al
    Response-independent survival benefit in metastatic colorectal cancer: a comparative analysis of N9741 and AVF2107.
    J Clin Oncol. 2008;26:183-9.
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65. NAGTEGAAL ID , Quirke P
    What is the role for the circumferential margin in the modern treatment of rectal cancer?
    J Clin Oncol. 2008;26:303-12.
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    December 2007
66. GHOBADI A , Kabbani W, Barker B, Dowell JE, et al
    Rectal GI stromal tumor mimicking a prostate mass.
    J Clin Oncol. 2007;25:5827-8.
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67. HILL DA , Furman WL, Billups CA, Riedley SE, et al
    Colorectal carcinoma in childhood and adolescence: a clinicopathologic review.
    J Clin Oncol. 2007;25:5808-14.
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68. MOCELLIN S , Pilati P, Lise M, Nitti D, et al
    Meta-analysis of hepatic arterial infusion for unresectable liver metastases from colorectal cancer: the end of an era?
    J Clin Oncol. 2007;25:5649-54.
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69. HOCHSTER HS , Luo W, Popa EC, Lyman BT, et al
    Phase II study of uracil-tegafur with leucovorin in elderly (> or = 75 years old) patients with colorectal cancer: ECOG 1299.
    J Clin Oncol. 2007;25:5397-402.
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70. SCOPE A , Agero AL, Dusza SW, Myskowski PL, et al
    Randomized double-blind trial of prophylactic oral minocycline and topical tazarotene for cetuximab-associated acne-like eruption.
    J Clin Oncol. 2007;25:5390-6.
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    November 2007
71. SHANKARAN V , McKoy JM, Dandade N, Nonzee N, et al
    Costs and cost-effectiveness of a low-intensity patient-directed intervention to promote colorectal cancer screening.
    J Clin Oncol. 2007;25:5248-53.
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72. TABERNERO J , Van Cutsem E, Diaz-Rubio E, Cervantes A, et al
    Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer.
    J Clin Oncol. 2007;25:5225-32.
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73. BUYSE M , Burzykowski T, Carroll K, Michiels S, et al
    Progression-free survival is a surrogate for survival in advanced colorectal cancer.
    J Clin Oncol. 2007;25:5218-24.
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74. YOTHERS G
    Toward progression-free survival as a primary end point in advanced colorectal cancer.
    J Clin Oncol. 2007;25:5153-4.
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75. GLYNNE-JONES R , Hoskin P
    Neoadjuvant cisplatin chemotherapy before chemoradiation: a flawed paradigm?
    J Clin Oncol. 2007;25:5281-6.
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76. KIM SG , Park EC, Park JH, Hahm MI, et al
    Initiation and discontinuation of complementary therapy among cancer patients.
    J Clin Oncol. 2007;25:5267-74.
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77. LU KH , Schorge JO, Rodabaugh KJ, Daniels MS, et al
    Prospective determination of prevalence of lynch syndrome in young women with endometrial cancer.
    J Clin Oncol. 2007;25:5158-64.
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78. KAUFF ND
    How should women with early-onset endometrial cancer be evaluated for lynch syndrome?
    J Clin Oncol. 2007;25:5143-6.
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79. CASSIDY J
    Capecitabine plus oxaliplatin in metastatic colorectal cancer.
    J Clin Oncol. 2007;25:5043-5.
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80. BUECHELE T
    Comments on final report of the AIO Colorectal Cancer Group Study: fluorouracil/oxaliplatin versus capecitabine/oxaliplatin.
    J Clin Oncol. 2007;25:5041-2.
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81. CEELEN WP
    Use of laparoscopy for rectal cancer: a word of caution.
    J Clin Oncol. 2007;25:5040.
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    October 2007
82. SALTZ LB , Rosen LS, Marshall JL, Belt RJ, et al
    Phase II Trial of Sunitinib in Patients With Metastatic Colorectal Cancer After Failure of Standard Therapy.
    J Clin Oncol. 2007;25:4793-9.
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83. FUCHS CS , Marshall J, Mitchell E, Wierzbicki R, et al
    Randomized, Controlled Trial of Irinotecan Plus Infusional, Bolus, or Oral Fluoropyrimidines in First-Line Treatment of Metastatic Colorectal Cancer: Results From the BICC-C Study.
    J Clin Oncol. 2007;25:4779-86.
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84. ADAM R , Aloia T, Levi F, Wicherts DA, et al
    Hepatic resection after rescue cetuximab treatment for colorectal liver metastases previously refractory to conventional systemic therapy.
    J Clin Oncol. 2007;25:4593-602.
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85. SALAMA JK , Mell LK, Schomas DA, Miller RC, et al
    Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience.
    J Clin Oncol. 2007;25:4581-6.
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86. TOMLINSON JS , Jarnagin WR, DeMatteo RP, Fong Y, et al
    Actual 10-year survival after resection of colorectal liver metastases defines cure.
    J Clin Oncol. 2007;25:4575-80.
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87. VAUTHEY JN
    Colorectal liver metastases: treat effectively up front and consider the borderline resectable.
    J Clin Oncol. 2007;25:4524-5.
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88. BASELGA J , Tabernero J
    Combined antiangiogenesis and antiepidermal growth factor receptor targeting in the treatment of cancer: hold back, we are not there yet.
    J Clin Oncol. 2007;25:4516-8.
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89. BONCZ I , Sebestyen A, Pinter I, Betlehem J, et al
    Age group specific gap between treatment cost of and mortality due to breast and colorectal cancer.
    J Clin Oncol. 2007;25:4501-2.
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90. COLLETTE L , Bosset JF, den Dulk M, Nguyen F, et al
    Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Cancer Ra
    J Clin Oncol. 2007;25:4379-86.
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91. MINSKY BD
    Adjuvant management of rectal cancer: the more we learn, the less we know.
    J Clin Oncol. 2007;25:4339-40.
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    September 2007
92. SVRCEK M , El-Bchiri J, Chalastanis A, Capel E, et al
    Specific clinical and biological features characterize inflammatory bowel disease associated colorectal cancers showing microsatellite instability.
    J Clin Oncol. 2007;25:4231-8.
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93. SALTZ LB , Lenz HJ, Kindler HL, Hochster HS, et al
    Randomized Phase II Trial of Cetuximab, Bevacizumab, and Irinotecan Compared With Cetuximab and Bevacizumab Alone in Irinotecan-Refractory Colorectal Cancer: The BOND-2 Study.
    J Clin Oncol. 2007;.
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94. TANG PA , Bentzen SM, Chen EX, Siu LL, et al
    Surrogate End Points for Median Overall Survival in Metastatic Colorectal Cancer: Literature-Based Analysis From 39 Randomized Controlled Trials of First-Line Chemotherapy.
    J Clin Oncol. 2007;.
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95. SARGENT DJ , Patiyil S, Yothers G, Haller DG, et al
    End Points for Colon Cancer Adjuvant Trials: Observations and Recommendations Based on Individual Patient Data From 20,898 Patients Enrolled Onto 18 Randomized Trials From the ACCENT Group.
    J Clin Oncol. 2007;.
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96. SCARTOZZI M , Bearzi I, Pierantoni C, Mandolesi A, et al
    Nuclear factor-kB tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy.
    J Clin Oncol. 2007;25:3930-5.
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97. GARCIA-DONAS J , Rodriguez N, Jara C, Urioste M, et al
    Retrorectal cystic hamartoma as benign cause of CA 19-9 elevation.
    J Clin Oncol. 2007;25:4012-4.
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98. HOCHSTER HS , Grothey A, Childs BH
    Use of calcium and magnesium salts to reduce oxaliplatin-related neurotoxicity.
    J Clin Oncol. 2007;25:4028-9.
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    August 2007
99. MAYER RJ
    Should Capecitabine Replace Infusional Fluorouracil and Leucovorin When Combined With Oxaliplatin in Metastatic Colorectal Cancer?
    J Clin Oncol. 2007;.
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100. ANDRE T , Quinaux E, Louvet C, Colin P, et al
     Phase III study comparing a semimonthly with a monthly regimen of fluorouracil and leucovorin as adjuvant treatment for stage II and III colon cancer patients: final results of GERCOR C96.1.
     J Clin Oncol. 2007;25:3732-8.
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101. ZHANG W , Press OA, Haiman CA, Yang DY, et al
     Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer.
     J Clin Oncol. 2007;25:3726-31.
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