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Colorectal Neoplasms

Free Subscription Articles published in Clin Cancer Res Retrieve available abstracts of 76 articles: HTML format Text format

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January 2012
1. HUANG F , Xu LA, Khambata-Ford S
   Correlation between Gene Expression of IGF-1R Pathway Markers and Cetuximab Benefit in Metastatic Colorectal Cancer.
   Clin Cancer Res. 2012.
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2. KAWADA K , Nakamoto Y, Kawada M, Hida K, et al
   Relationship between 18F-Fluorodeoxyglucose Accumulation and KRAS/BRAF Mutations in Colorectal Cancer.
   Clin Cancer Res. 2012.
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3. SPINDLER KL , Pallisgaard N, Vogelius I, Jakobsen A, et al
   Quantitative Cell Free DNA, KRAS and BRAF mutations in Plasma from Patients with Metastatic Colorectal Cancer during Treatment with Cetuximab and Irinotecan.
   Clin Cancer Res. 2012.
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   December 2011
4. GESPACH C
   Increasing potential of HER3 signaling in colon cancer progression and therapy.
   Clin Cancer Res. 2011.
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5. MIGLIORE C , Martin V, Leoni VP, Restivo A, et al
   MIR-1 DOWNREGULATION COOPERATES WITH MACC1 IN PROMOTING MET OVEREXPRESSION IN HUMAN COLON CANCER.
   Clin Cancer Res. 2011.
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6. MORELLI MP , Tentler JJ, Kulikowski GN, Tan AC, et al
   Preclinical Activity of the Rational Combination of Selumetinib (AZD6244) in Combination with Vorinostat in KRAS Mutant Colorectal Cancer Models.
   Clin Cancer Res. 2011.
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7. DE WEGER VA , Turksma AW, Voorham QJ, Euler Z, et al
   Clinical effects of Adjuvant Active Specific Immunotherapy differ between Patients with Microsatellite Stable and Microsatellite Instable Colon Cancer.
   Clin Cancer Res. 2011.
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8. OGINO S , Shima K, Meyerhardt J, McCleary N, et al
   Predictive and Prognostic Roles of BRAF Mutation in Stage III Colon Cancer: Results from Intergroup Trial CALGB 89803.
   Clin Cancer Res. 2011.
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9. BEJI A , Horst D, Engel J, Kirchner T, et al
   Towards the prognostic significance and therapeutic potential of HER3 receptor tyrosine kinase in human colon cancer.
   Clin Cancer Res. 2011.
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   October 2011
10. KAHLERT C , Lahes S, Radhakrishnan P, Dutta S, et al
    Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro.
    Clin Cancer Res. 2011.
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11. VILAR E , Tabernero J, Gruber SB
    Micromanaging the classification of colon cancer. The role of the microRNAome.
    Clin Cancer Res. 2011.
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12. ZAANAN A , Flejou JF, Emile JF, Des Guetz G, et al
    Defective Mismatch Repair status as a prognostic biomarker of disease-free survival in stage III colon cancer patients treated with adjuvant FOLFOX chemotherapy.
    Clin Cancer Res. 2011.
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13. SMITS KM , Paranjape T, Nallur S, Wouters KA, et al
    A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer.
    Clin Cancer Res. 2011.
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14. COGHILL AE , Newcomb PA, Poole EM, Hutter CM, et al
    Genetic Variation in Inflammatory Pathways is Related to Colorectal Cancer Survival.
    Clin Cancer Res. 2011.
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15. BALAGUER F , Moreira L, Lozano JJ, Link A, et al
    Colorectal cancers with microsatellite instability display unique miRNA profiles.
    Clin Cancer Res. 2011;17:6239-49.
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    September 2011
16. AZZOPARDI N , Lecomte T, Ternant D, Boisdron-Celle M, et al
    Cetuximab Pharmacokinetics Influences Progression-Free Survival of Metastatic Colorectal Cancer Patients.
    Clin Cancer Res. 2011.
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17. BARTLEY AN , Yao H, Barkoh BA, Ivan C, et al
    Complex Patterns of Altered MicroRNA Expression during the Adenoma-Adenocarcinoma Sequence for Microsatellite-stable Colorectal Cancer.
    Clin Cancer Res. 2011.
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18. GERGER A , Zhang W, Yang D, Bohanes P, et al
    Common cancer stem cell gene variants predict colon cancer recurrence.
    Clin Cancer Res. 2011.
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    August 2011
19. POINDESSOUS V , Ouaret D, El Ouadrani K, Battistella A, et al
    EGFR- and VEGF(R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies.
    Clin Cancer Res. 2011.
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20. BLANK PR , Moch H, Szucs TD, Schwenkglenks M, et al
    KRAS and BRAF mutation analysis in metastatic colorectal cancer: a cost-effectiveness analysis from a Swiss perspective.
    Clin Cancer Res. 2011.
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21. SOLDEVILLA B , Diaz R, Silva J, Campos-Martin Y, et al
    Prognostic impact of {triangleup}TAp73 isoform levels and their target genes in colon cancer patients.
    Clin Cancer Res. 2011.
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22. URICK ME , Chung EJ, Shield WP 3rd, Gerber N, et al
    Enhancement of 5-fluorouracil-induced in vitro and in vivo radiosensitization with MEK inhibition.
    Clin Cancer Res. 2011;17:5038-47.
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23. HU-LIESKOVAN S , Vallbohmer D, Zhang W, Yang D, et al
    EGF61 polymorphism predicts complete pathologic response to cetuximab-based chemoradiation independent of KRAS status in locally advanced rectal cancer patients.
    Clin Cancer Res. 2011;17:5161-9.
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24. TOH YM , Li TK
    Mitoxantrone inhibits HIF-1alpha expression in a topoisomerase II-independent pathway.
    Clin Cancer Res. 2011;17:5026-37.
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    July 2011
25. GERGER A , El-Khoueiry A, Zhang W, Yang D, et al
    Pharmacogenetic angiogenesis profiling for first-line bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
    Clin Cancer Res. 2011.
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26. CHU D , Zhou Y, Zhang Z, Li Y, et al
    Notch1 Expression is an Independent Predictor of Prognosis in Colorectal Cancer, Which is Related to p65 Status.
    Clin Cancer Res. 2011.
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27. WONG H , Alicke B, West KA, Pacheco P, et al
    Pharmacokinetic-pharmacodynamic analysis of vismodegib in preclinical models of mutational and ligand-dependent Hedgehog pathway activation.
    Clin Cancer Res. 2011;17:4682-92.
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28. MAXWELL F , McGlynn LM, Muir HC, Talwar D, et al
    Telomere attrition and decreased Fetuin A levels indicate accelerated biological ageing and are implicated in the pathogenesis of Colorectal Cancer.
    Clin Cancer Res. 2011.
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29. SUN Y , Yokoi K, Li H, Gao J, et al
    NGAL expression is elevated in both colorectal adenoma-carcinoma sequence and cancer progression and enhances tumorigenesis in xenograft mouse models.
    Clin Cancer Res. 2011;17:4331-40.
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30. SHARMA AK , Kline CL, Berg A, Amin S, et al
    The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.
    Clin Cancer Res. 2011;17:4474-83.
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    June 2011
31. SPORN JC , Hothorn T, Jung BH
    BARD1 expression predicts outcome in colon cancer.
    Clin Cancer Res. 2011.
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32. CASADO E , Garcia VM, Sanchez JJ, Blanco M, et al
    A combined strategy of SAGE and quantitative PCR Provides a 13-gene signature that predicts preoperative chemoradiotherapy response and outcome in rectal cancer.
    Clin Cancer Res. 2011;17:4145-54.
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33. MOLINARI F , Felicioni L, Buscarino M, De Dosso S, et al
    Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer.
    Clin Cancer Res. 2011.
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34. KOUKOURAKIS MI , Giatromanolaki A, Sivridis E, Gatter KC, et al
    Prognostic and predictive role of lactate dehydrogenase 5 ( LDH5) expression in colorectal cancer patients treated with PTK787/ZK 222584 (Vatalanib) anti-angiogenic therapy.
    Clin Cancer Res. 2011.
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35. YANG L , Zhang H, Zhou ZG, Yan H, et al
    Biological function and prognostic significance of peroxisome proliferator-activated receptor delta in rectal cancer.
    Clin Cancer Res. 2011;17:3760-70.
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36. THOMPSON PA , Gerner EW
    Of timing and surrogates: a way forward for cancer chemoprevention.
    Clin Cancer Res. 2011;17:3509-11.
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37. TAKAYAMA T , Nagashima H, Maeda M, Nojiri S, et al
    Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps.
    Clin Cancer Res. 2011;17:3803-11.
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    May 2011
38. GRIMMINGER PP , Danenberg P, Dellas K, Arnold D, et al
    Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
    Clin Cancer Res. 2011;17:3469-77.
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39. OLMOS D , Barker D, Sharma R, Brunetto AT, et al
    Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced solid malignancies.
    Clin Cancer Res. 2011;17:3420-30.
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40. LIN BR , Chang CC, Chen RJ, Jeng YM, et al
    Connective Tissue Growth Factor Acts as a Therapeutic Agent and Predictor for Peritoneal Carcinomatosis of Colorectal Cancer.
    Clin Cancer Res. 2011.
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41. TANAKA M , Chang P, Li Y, Li D, et al
    Association of CHFR Promoter Methylation with Disease Recurrence in Locally Advanced Colon Cancer.
    Clin Cancer Res. 2011.
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42. WU F , Zhou Q, Yang J, Duan GJ, et al
    Endogenous axon guiding chemorepulsant semaphorin-3F inhibits the growth and metastasis of colorectal carcinoma.
    Clin Cancer Res. 2011;17:2702-11.
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43. BRETTINGHAM-MOORE KH , Duong CP, Greenawalt DM, Heriot AG, et al
    Pretreatment transcriptional profiling for predicting response to neoadjuvant chemoradiotherapy in rectal adenocarcinoma.
    Clin Cancer Res. 2011;17:3039-47.
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    April 2011
44. HOLDHOFF M , Schmidt K, Diehl F, Agrawal N, et al
    Detection of tumor DNA at the margins of colorectal cancer liver metastasis.
    Clin Cancer Res. 2011.
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45. LI D , Peng Z, Tang H, Wei P, et al
    KLF4-Mediated Negative Regulation of IFITM3 Expression Plays a Critical Role in Colon Cancer Pathogenesis.
    Clin Cancer Res. 2011.
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46. WONG JC , Chan SK, Schaeffer DF, Sagaert X, et al
    Absence of MMP2 expression correlates with poor clinical outcomes in rectal cancer, and is distinct from MMP1-related outcomes in colon cancer.
    Clin Cancer Res. 2011.
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47. GROTHEY A
    Does Stage II Colorectal Cancer Need to be Redefined?
    Clin Cancer Res. 2011.
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48. DEENEN MJ , Tol J, Burylo AM, Doodeman VD, et al
    Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer.
    Clin Cancer Res. 2011.
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49. BIROCCIO A , Porru M, Rizzo A, Salvati E, et al
    DNA damage persistence as determinant of tumor sensitivity to the combination of Topo I inhibitors and telomere-targeting agents.
    Clin Cancer Res. 2011;17:2227-36.
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50. WANG X , Liu X, Li AY, Chen L, et al
    Overexpression of HMGA2 promotes metastasis and impacts survival of colorectal cancers.
    Clin Cancer Res. 2011;17:2570-80.
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51. LIAO WT , Jiang D, Yuan J, Cui YM, et al
    HOXB7 as prognostic factor and mediator of colorectal cancer progression.
    Clin Cancer Res. 2011.
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52. AFZAL S , Gusella M, Vainer B, Vogel U, et al
    Combinations of polymorphisms in genes involved in the 5-Fluorouracil metabolism pathway are associated with gastrointestinal toxicity in chemotherapy treated colorectal cancer patients.
    Clin Cancer Res. 2011.
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53. GARRE P , Briceno V, Xicola RM, Doyle BJ, et al
    Analysis of the oxidative damage repair genes NUDT1, OGG1, and MUTYH in patients from mismatch repair proficient HNPCC families (MSS-HNPCC).
    Clin Cancer Res. 2011;17:1701-12.
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54. CARONIA D , Martin M, Sastre J, de la Torre J, et al
    A polymorphism in the cytidine deaminase promoter predicts severe capecitabine-induced hand-foot syndrome.
    Clin Cancer Res. 2011;17:2006-13.
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    March 2011
55. GALIMI F , Torti D, Sassi F, Isella C, et al
    Genetic and expression analysis of MET, MACC1 and HGF in metastatic colorectal cancer: Response to Met inhibition in patient xenografts and pathological correlations.
    Clin Cancer Res. 2011.
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56. BACKSHALL A , Sharma R, Clarke S, Keun H, et al
    Pharmaco-metabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine.
    Clin Cancer Res. 2011.
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57. CARMONA FJ , Esteller M
    Moving closer to a prognostic DNA methylation signature in colon cancer.
    Clin Cancer Res. 2011;17:1215-7.
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58. MORIKAWA T , Baba Y, Yamauchi M, Kuchiba A, et al
    STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers.
    Clin Cancer Res. 2011;17:1452-62.
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59. SPRENGER T , Rodel F, Beissbarth T, Conradi LC, et al
    Failure of downregulation of survivin following neoadjuvant radiochemotherapy in rectal cancer is associated with distant metastases and shortened survival.
    Clin Cancer Res. 2011;17:1623-31.
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    February 2011
60. HALAMA N , Braun M, Kahlert C, Spille A, et al
    Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines.
    Clin Cancer Res. 2011;17:678-89.
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61. HYSLOP T , Weinberg DS, Schulz S, Barkun A, et al
    Occult tumor burden predicts disease recurrence in lymph node-negative colorectal cancer.
    Clin Cancer Res. 2011.
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62. JUNG Y , Lee S, Choi HS, Kim SN, et al
    Clinical Validation of Colorectal Cancer Biomarkers Identified from Bioinformatics Analysis of Public Expression Data.
    Clin Cancer Res. 2011.
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    January 2011
63. YI JM , Dhir M, Van Neste L, Downing SR, et al
    Genomic and epigenomic integration identifies a prognostic signature in colon cancer.
    Clin Cancer Res. 2011.
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64. YIN M , Yan J, Martinez-Balibrea E, Graziano F, et al
    ERCC1 and ERCC2/XPD Polymorphisms Predict Clinical Outcomes of Oxaliplatin-based Chemotherapies in Gastric and Colorectal Cancer: A Systemic Review and Meta-analysis.
    Clin Cancer Res. 2011.
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65. TSUKAMOTO S , Ishikawa T, Iida S, Ishiguro M, et al
    Clinical Significance of Osteoprotegerin Expression in Human Colorectal Cancer.
    Clin Cancer Res. 2011.
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66. MOROZ MA , Kochetkov T, Cai S, Wu J, et al
    Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging.
    Clin Cancer Res. 2011.
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67. TIE J , Lipton L, Desai J, Gibbs P, et al
    KRAS Mutation is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer.
    Clin Cancer Res. 2011.
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68. KIM JC , Kim SY, Cho DH, Ha YJ, et al
    Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer.
    Clin Cancer Res. 2011.
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69. FAN J , Yan D, Teng M, Tang H, et al
    Digital Transcript Profile Analysis With aRNA-LongSAGE Validates FERMT1 as a Potential Novel Prognostic Marker for Colon Cancer.
    Clin Cancer Res. 2011.
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    December 2010
70. HE Y , Van't Veer LJ, Lopez-Yurda M, van de Velde CJ, et al
    Do rectal cancer patients with PIK3CA mutations benefit from preoperative radiotherapy with regard to local recurrences?
    Clin Cancer Res. 2010;16:6179.
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71. YU P , Steel JC, Zhang M, Morris JC, et al
    Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model.
    Clin Cancer Res. 2010;16:6019-28.
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72. FINI L , Piazzi G, Ceccarelli C, Daoud Y, et al
    Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice.
    Clin Cancer Res. 2010;16:5703-11.
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73. HERBST RS , Kurzrock R, Hong DS, Valdivieso M, et al
    A first-in-human study of conatumumab in adult patients with advanced solid tumors.
    Clin Cancer Res. 2010;16:5883-91.
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    November 2010
74. GAUJOUX S , Pinson S, Gimenez-Roqueplo AP, Amar L, et al
    Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers.
    Clin Cancer Res. 2010;16:5133-41.
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    October 2010
75. TAKAHASHI A , Ohkohchi N, Yasunaga M, Kuroda J, et al
    Detailed distribution of NK012, an SN-38-incorporating micelle, in the liver and its potent antitumor effects in mice bearing liver metastases.
    Clin Cancer Res. 2010;16:4822-31.
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    September 2010
76. RAVICHANDRAN K , Velmurugan B, Gu M, Singh RP, et al
    Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice.
    Clin Cancer Res. 2010;16:4595-606.
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