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Articles published in Clin Cancer Res

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    March 2010
  1. SINICROPE FA , Foster NR, Sargent DJ, O'Connell MJ, et al
    Obesity Is an Independent Prognostic Variable in Colon Cancer Survivors.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  2. WALSH MD , Buchanan DD, Cummings MC, Pearson SA, et al
    Lynch Syndrome-Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  3. DAHLIN AM , Palmqvist R, Henriksson ML, Jacobsson M, et al
    The Role of the CpG Island Methylator Phenotype in Colorectal Cancer Prognosis Depends on Microsatellite Instability Screening Status.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


    February 2010
  4. PANDE M , Lynch PM, Hopper JL, Jenkins MA, et al
    Smoking and Colorectal Cancer in Lynch Syndrome: Results from the Colon Cancer Family Registry and The University of Texas M.D. Anderson Cancer Center.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


    December 2009
  5. YAGI K , Akagi K, Hayashi H, Nagae G, et al
    Three DNA Methylation Epigenotypes in Human Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  6. NAIK S , Dothager RS, Marasa J, Lewis CL, et al
    Vascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant {beta}-Catenin Activation in Colon Cancer.
    Clin Cancer Res. 2009;15:7529-7537.
    PubMed     Text format     Related articles    Abstract available


  7. BANCK MS , Grothey A
    Biomarkers of Resistance to Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer.
    Clin Cancer Res. 2009;15:7492-7501.
    PubMed     Text format     Related articles    Abstract available


  8. TOH HC , Wang WW, Chia WK, Kvistborg P, et al
    Clinical Benefit of Allogeneic Melanoma Cell Lysate-Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  9. JORISSEN RN , Gibbs P, Christie M, Prakash S, et al
    Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  10. KOPETZ S , Abbruzzese JL
    Barriers to Integrating Gene Profiling for Stage II Colon Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


    November 2009
  11. GULHATI P , Cai Q, Li J, Liu J, et al
    Targeted Inhibition of Mammalian Target of Rapamycin Signaling Inhibits Tumorigenesis of Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  12. OGINO S , Meyerhardt JA, Irahara N, Niedzwiecki D, et al
    KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  13. KOUKOURAKIS MI , Giatromanolaki A, Sheldon H, Buffa FM, et al
    Phase I/II Trial of Bevacizumab and Radiotherapy for Locally Advanced Inoperable Colorectal Cancer: Vasculature-Independent Radiosensitizing Effect of Bevacizumab.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


    October 2009
  14. YAN T , Seo Y, Kinsella TJ
    Differential Cellular Responses to Prolonged LDR-IR in MLH1-Proficient and MLH1-Deficient Colorectal Cancer HCT116 Cells.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  15. MCGILVRAY RW , Eagle RA, Watson NF, Al-Attar A, et al
    NKG2D Ligand Expression in Human Colorectal Cancer Reveals Associations with Prognosis and Evidence for Immunoediting.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  16. OGINO S , Nosho K, Irahara N, Meyerhardt JA, et al
    Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
    Clin Cancer Res. 2009;15:6412-20.
    PubMed     Text format     Related articles    Abstract available


  17. ZELL JA , Ziogas A, Ignatenko N, Honda J, et al
    Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival.
    Clin Cancer Res. 2009;15:6208-16.
    PubMed     Text format     Related articles    Abstract available


    September 2009
  18. HENDIFAR A , Yang D, Lenz F, Lurje G, et al
    Gender Disparities in Metastatic Colorectal Cancer Survival.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  19. LEE BB , Lee EJ, Jung EH, Chun HK, et al
    Aberrant Methylation of APC, MGMT, RASSF2A, and Wif-1 Genes in Plasma as a Biomarker for Early Detection of Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  20. MEYERHARDT JA , Ogino S, Kirkner GJ, Chan AT, et al
    Interaction of Molecular Markers and Physical Activity on Mortality in Patients with Colon Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


    August 2009
  21. HU H , Sun L, Guo C, Liu Q, et al
    Tumor Cell-Microenvironment Interaction Models Coupled with Clinical Validation Reveal CCL2 and SNCG as Two Predictors of Colorectal Cancer Hepatic Metastasis.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  22. HERRERA M , Dominguez G, Garcia JM, Pena C, et al
    Differences in Repair of DNA Cross-links between Lymphocytes and Epithelial Tumor Cells from Colon Cancer Patients Measured In vitro with the Comet Assay.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  23. SHIN SW , Seo CY, Han H, Han JY, et al
    15d-PGJ2 Induces Apoptosis by Reactive Oxygen Species-mediated Inactivation of Akt in Leukemia and Colorectal Cancer Cells and Shows In vivo Antitumor Activity.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  24. BOSMAN FT , Yan P, Tejpar S, Fiocca R, et al
    Tissue Biomarker Development in a Multicentre Trial Context: a Feasibility Study on the PETACC3 Stage II and III Colon Cancer Adjuvant Treatment Trial.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  25. GARCIA-ALBENIZ X , Gallego R
    Prognostic role of plasma insulin-like growth factor (IGF) and IGF-binding protein 3 in metastatic colorectal cancer.
    Clin Cancer Res. 2009;15:5288.
    PubMed     Text format     Related articles   


    July 2009
  26. LOPEZ-VICENTE L , Armengol G, Pons B, Coch L, et al
    Regulation of replicative and stress-induced senescence by RSK4, which is down-regulated in human tumors.
    Clin Cancer Res. 2009;15:4546-53.
    PubMed     Text format     Related articles    Abstract available


  27. BARANOVSKAYA S , Martin Y, Alonso S, Pisarchuk KL, et al
    Down-regulation of Epidermal Growth Factor Receptor by Selective Expansion of a 5'-End Regulatory Dinucleotide Repeat in Colon Cancer with Microsatellite Instability.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  28. BABA Y , Nosho K, Shima K, Freed E, et al
    Relationship of CDX2 Loss with Molecular Features and Prognosis in Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


    June 2009
  29. YEN LC , Yeh YS, Chen CW, Wang HM, et al
    Detection of KRAS Oncogene in Peripheral Blood as a Predictor of the Response to Cetuximab Plus Chemotherapy in Patients with Metastatic Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  30. OGINO S , Nosho K, Irahara N, Kure S, et al
    A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  31. YAMAMICHI N , Shimomura R, Inada KI, Sakurai K, et al
    Locked Nucleic Acid In situ Hybridization Analysis of miR-21 Expression during Colorectal Cancer Development.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  32. HELLEBREKERS DM , Lentjes MH, van den Bosch SM, Melotte V, et al
    GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


    May 2009
  33. NOSHO K , Shima K, Irahara N, Kure S, et al
    DNMT3B Expression Might Contribute to CpG Island Methylator Phenotype in Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  34. RUDOLPH D , Steegmaier M, Hoffmann M, Grauert M, et al
    BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity.
    Clin Cancer Res. 2009;15:3094-102.
    PubMed     Text format     Related articles    Abstract available


  35. GOMES AJ , Roy HK, Turzhitsky V, Kim Y, et al
    Rectal mucosal microvascular blood supply increase is associated with colonic neoplasia.
    Clin Cancer Res. 2009;15:3110-7.
    PubMed     Text format     Related articles    Abstract available


  36. PAYA A , Alenda C, Perez-Carbonell L, Rojas E, et al
    Utility of p16 immunohistochemistry for the identification of Lynch syndrome.
    Clin Cancer Res. 2009;15:3156-62.
    PubMed     Text format     Related articles    Abstract available


  37. SHIMIZU M , Shirakami Y, Iwasa J, Shiraki M, et al
    Supplementation with branched-chain amino acids inhibits azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice.
    Clin Cancer Res. 2009;15:3068-75.
    PubMed     Text format     Related articles    Abstract available


    April 2009
  38. FAKIH MG , Pendyala L, Fetterly G, Toth K, et al
    A Phase I, Pharmacokinetic and Pharmacodynamic Study on Vorinostat in Combination with 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Refractory Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  39. VILAR E , Mukherjee B, Kuick R, Raskin L, et al
    Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway.
    Clin Cancer Res. 2009;15:2829-39.
    PubMed     Text format     Related articles    Abstract available


  40. PRENEN H , De Schutter J, Jacobs B, De Roock W, et al
    PIK3CA Mutations Are Not a Major Determinant of Resistance to the Epidermal Growth Factor Receptor Inhibitor Cetuximab in Metastatic Colorectal Cancer.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  41. KATKOORI VR , Jia X, Shanmugam C, Wan W, et al
    Prognostic significance of p53 codon 72 polymorphism differs with race in colorectal adenocarcinoma.
    Clin Cancer Res. 2009;15:2406-16.
    PubMed     Text format     Related articles    Abstract available


  42. BANDRES E , Bitarte N, Arias F, Agorreta J, et al
    microRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells.
    Clin Cancer Res. 2009;15:2281-90.
    PubMed     Text format     Related articles    Abstract available


  43. WONG CH , Baehner FL, Spassov DS, Ahuja D, et al
    Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers.
    Clin Cancer Res. 2009;15:2311-22.
    PubMed     Text format     Related articles    Abstract available


  44. SAKAMOTO K , Maeda S, Hikiba Y, Nakagawa H, et al
    Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth.
    Clin Cancer Res. 2009;15:2248-58.
    PubMed     Text format     Related articles    Abstract available


    March 2009
  45. CAFFERATA EG , Maccio DR, Lopez MV, Viale DL, et al
    A Novel A33 Promoter-Based Conditionally Replicative Adenovirus Suppresses Tumor Growth and Eradicates Hepatic Metastases in Human Colon Cancer Models.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  46. BASS SE , Sienkiewicz P, Macdonald CJ, Cheng RY, et al
    Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells.
    Clin Cancer Res. 2009;15:1964-72.
    PubMed     Text format     Related articles    Abstract available


  47. BERTAGNOLLI MM , Warren RS, Niedzwiecki D, Mueller E, et al
    p27Kip1 in Stage III Colon Cancer: Implications for Outcome following Adjuvant Chemotherapy in Cancer and Leukemia Group B Protocol 89803.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  48. DENG G , Kakar S, Okudiara K, Choi E, et al
    Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs.
    Clin Cancer Res. 2009;15:1519-26.
    PubMed     Text format     Related articles    Abstract available


  49. LI B , VanRoey M, Wang C, Chen TH, et al
    Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor--secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors.
    Clin Cancer Res. 2009;15:1623-34.
    PubMed     Text format     Related articles    Abstract available


    February 2009
  50. CHEN E , Jonker D, Gauthier I, MacLean M, et al
    Phase I study of cediranib in combination with oxaliplatin and infusional 5-Fluorouracil in patients with advanced colorectal cancer.
    Clin Cancer Res. 2009;15:1481-6.
    PubMed     Text format     Related articles    Abstract available


  51. PENCREACH E , Guerin E, Nicolet C, Lelong-Rebel I, et al
    Marked Activity of Irinotecan and Rapamycin Combination toward Colon Cancer Cells In vivo and In vitro Is Mediated through Cooperative Modulation of the Mammalian Target of Rapamycin/Hypoxia-Inducible Factor-1{alpha} Axis.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  52. KUMAR K , Brim H, Giardiello F, Smoot DT, et al
    Distinct BRAF (V600E) and KRAS Mutations in High Microsatellite Instability Sporadic Colorectal Cancer in African Americans.
    Clin Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  53. SPEETJENS FM , Kuppen PJ, Welters MJ, Essahsah F, et al
    Induction of p53-Specific Immunity by a p53 Synthetic Long Peptide Vaccine in Patients Treated for Metastatic Colorectal Cancer.
    Clin Cancer Res. 2009;15:1086-95.
    PubMed     Text format     Related articles    Abstract available


  54. WONG SC , Chan CM, Ma BB, Hui EP, et al
    Clinical Significance of Cytokeratin 20-Positive Circulating Tumor Cells Detected by a Refined Immunomagnetic Enrichment Assay in Colorectal Cancer Patients.
    Clin Cancer Res. 2009;15:1005-1012.
    PubMed     Text format     Related articles    Abstract available


  55. GERNER EW , Meyskens FL Jr
    Combination chemoprevention for colon cancer targeting polyamine synthesis and inflammation.
    Clin Cancer Res. 2009;15:758-61.
    PubMed     Text format     Related articles    Abstract available


  56. MEYER C , Brieger A, Plotz G, Weber N, et al
    An interstitial deletion at 3p21.3 results in the genetic fusion of MLH1 and ITGA9 in a Lynch syndrome family.
    Clin Cancer Res. 2009;15:762-9.
    PubMed     Text format     Related articles    Abstract available


    January 2009
  57. GADE TP , Buchanan IM, Motley MW, Mazaheri Y, et al
    Imaging intratumoral convection: pressure-dependent enhancement in chemotherapeutic delivery to solid tumors.
    Clin Cancer Res. 2009;15:247-55.
    PubMed     Text format     Related articles    Abstract available


    December 2008
  58. SCHLEMMER M , Kuehl M, Schalhorn A, Rauch J, et al
    Tissue levels of reduced folates in patients with colorectal carcinoma after infusion of folinic acid at various dose levels.
    Clin Cancer Res. 2008;14:7930-4.
    PubMed     Text format     Related articles    Abstract available


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