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Articles published in Cancer Res

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    February 2010
  1. KANEDA H , Arao T, Tanaka K, Tamura D, et al
    FOXQ1 Is Overexpressed in Colorectal Cancer and Enhances Tumorigenicity and Tumor Growth.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  2. QU Z , Yan P, Fu J, Jiang J, et al
    DNA Methylation-Dependent Repression of PDZ-LIM Domain-Containing Protein 2 in Colon Cancer and Its Role as a Potential Therapeutic Target.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  3. SPEETJENS FM , Kuppen PJ
    Comment re: Intratumoral Immune Reaction in Human Colorectal Cancer.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  4. SIKANDAR SS , Pate KT, Anderson S, Dizon D, et al
    NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  5. SLATTERY ML , Herrick J, Curtin K, Samowitz W, et al
    Increased Risk of Colon Cancer Associated with a Genetic Polymorphism of SMAD7.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


    January 2010
  6. GARCIA-OLMO DC , Dominguez C, Garcia-Arranz M, Anker P, et al
    Cell-Free Nucleic Acids Circulating in the Plasma of Colorectal Cancer Patients Induce the Oncogenic Transformation of Susceptible Cultured Cells.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  7. WILSON AJ , Chueh AC, Togel L, Corner GA, et al
    Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors Is Mediated by an Sp1/Sp3-Activated Transcriptional Program Involving Immediate-Early Gene Induction.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


  8. XIA D , Holla VR, Wang D, Menter DG, et al
    HEF1 Is a Crucial Mediator of the Proliferative Effects of Prostaglandin E2 on Colon Cancer Cells.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available


    October 2009
  9. KIKUCHI H , Pino MS, Zeng M, Shirasawa S, et al
    Oncogenic KRAS and BRAF Differentially Regulate Hypoxia-Inducible Factor-1{alpha} and -2{alpha} in Colon Cancer.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  10. RAO CV , Steele VE, Swamy MV, Patlolla JM, et al
    Inhibition of Azoxymethane-Induced Colorectal Cancer by CP-31398, a TP53 Modulator, Alone or in Combination with Low Doses of Celecoxib in Male F344 Rats.
    Cancer Res. 2009;69:8175-82.
    PubMed     Text format     Related articles    Abstract available


  11. WANG P , Zou F, Zhang X, Li H, et al
    microRNA-21 Negatively Regulates Cdc25A and Cell Cycle Progression in Colon Cancer Cells.
    Cancer Res. 2009;69:8157-65.
    PubMed     Text format     Related articles    Abstract available


    September 2009
  12. YOSHIMURA K , Meckel KF, Laird LS, Chia CY, et al
    Integrin alpha2 mediates selective metastasis to the liver.
    Cancer Res. 2009;69:7320-8.
    PubMed     Text format     Related articles    Abstract available


  13. DOPESO H , Mateo-Lozano S, Mazzolini R, Rodrigues P, et al
    The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.
    Cancer Res. 2009;69:7430-8.
    PubMed     Text format     Related articles    Abstract available


  14. MATSUMOTO K , Arao T, Tanaka K, Kaneda H, et al
    mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells.
    Cancer Res. 2009;69:7160-4.
    PubMed     Text format     Related articles    Abstract available


  15. SEO Y , Kinsella TJ
    Essential role of DNA base excision repair on survival in an acidic tumor microenvironment.
    Cancer Res. 2009;69:7285-93.
    PubMed     Text format     Related articles    Abstract available


  16. JIN B , Yao B, Li JL, Fields CR, et al
    DNMT1 and DNMT3B Modulate Distinct Polycomb-Mediated Histone Modifications in Colon Cancer.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  17. SPAIN SL , Cazier JB, Houlston R, Carvajal-Carmona L, et al
    Colorectal Cancer Risk Is Not Associated with Increased Levels of Homozygosity in a Population from the United Kingdom.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


    August 2009
  18. MUELLER J , Gazzoli I, Bandipalliam P, Garber JE, et al
    Comprehensive Molecular Analysis of Mismatch Repair Gene Defects in Suspected Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Cases.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  19. YODKEEREE S , Sung B, Limtrakul P, Aggarwal BB, et al
    Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  20. AMBROSINI G , Seelman SL, Schwartz GK
    Differentiation-related gene-1 decreases Bim stability by proteasome-mediated degradation.
    Cancer Res. 2009;69:6115-21.
    PubMed     Text format     Related articles    Abstract available


    July 2009
  21. EDWARDS RA , Witherspoon M, Wang K, Afrasiabi K, et al
    Epigenetic Repression of DNA Mismatch Repair by Inflammation and Hypoxia in Inflammatory Bowel Disease-Associated Colorectal Cancer.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  22. PANNEQUIN J , Bonnans C, Delaunay N, Ryan J, et al
    The Wnt Target Jagged-1 Mediates the Activation of Notch Signaling by Progastrin in Human Colorectal Cancer Cells.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  23. COLOMBO MP , Piconese S
    Polyps wrap mast cells and Treg within tumorigenic tentacles.
    Cancer Res. 2009;69:5619-22.
    PubMed     Text format     Related articles    Abstract available


  24. HARTMAN J , Edvardsson K, Lindberg K, Zhao C, et al
    Tumor Repressive Functions of Estrogen Receptor {beta} in SW480 Colon Cancer Cells.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  25. GOUNARIS E , Blatner NR, Dennis K, Magnusson F, et al
    T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis.
    Cancer Res. 2009;69:5490-7.
    PubMed     Text format     Related articles    Abstract available


  26. SUBRAMANIAN H , Roy HK, Pradhan P, Goldberg MJ, et al
    Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy.
    Cancer Res. 2009;69:5357-63.
    PubMed     Text format     Related articles    Abstract available


    June 2009
  27. KAAKS R , Stattin P, Villar S, Poetsch AR, et al
    Insulin-like Growth Factor-II Methylation Status in Lymphocyte DNA and Colon Cancer Risk in the Northern Sweden Health and Disease Cohort.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  28. MATSUZAKI K , Kitano C, Murata M, Sekimoto G, et al
    Smad2 and Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions Transmit Malignant TGF-{beta} Signal in Later Stages of Human Colorectal Cancer.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  29. JEONG CH , Bode AM, Pugliese A, Cho YY, et al
    [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  30. FERNANDO S , Fletcher BS
    Targeting tumor endothelial marker 8 in the tumor vasculature of colorectal carcinomas in mice.
    Cancer Res. 2009;69:5126-32.
    PubMed     Text format     Related articles    Abstract available


  31. GUDA K , Natale L, Lutterbaugh J, Wiesner GL, et al
    Infrequent Detection of Germline Allele-Specific Expression of TGFBR1 in Lymphoblasts and Tissues of Colon Cancer Patients.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  32. LIAO YC , Chen NT, Shih YP, Dong Y, et al
    Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer through beta-catenin.
    Cancer Res. 2009;69:4563-6.
    PubMed     Text format     Related articles    Abstract available


  33. WESTBROOK AM , Wei B, Braun J, Schiestl RH, et al
    Intestinal mucosal inflammation leads to systemic genotoxicity in mice.
    Cancer Res. 2009;69:4827-34.
    PubMed     Text format     Related articles    Abstract available


  34. DAI Y , Qiao L, Chan KW, Yang M, et al
    Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis.
    Cancer Res. 2009;69:4776-83.
    PubMed     Text format     Related articles    Abstract available


  35. HIRAYAMA A , Kami K, Sugimoto M, Sugawara M, et al
    Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry.
    Cancer Res. 2009;69:4918-25.
    PubMed     Text format     Related articles    Abstract available


    May 2009
  36. INNOMINATO PF , Focan C, Gorlia T, Moreau T, et al
    Circadian Rhythm in Rest and Activity: A Biological Correlate of Quality of Life and a Predictor of Survival in Patients with Metastatic Colorectal Cancer.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  37. VILORIA CG , Obaya AJ, Moncada-Pazos A, Llamazares M, et al
    Genetic Inactivation of ADAMTS15 Metalloprotease in Human Colorectal Cancer.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  38. SZOKALSKA A , Makowski M, Nowis D, Wilczynski GM, et al
    Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of endoplasmic reticulum stress and unfolded protein response.
    Cancer Res. 2009;69:4235-43.
    PubMed     Text format     Related articles    Abstract available


  39. MCCONNELL BB , Bialkowska AB, Nandan MO, Ghaleb AM, et al
    Haploinsufficiency of Kruppel-like factor 5 rescues the tumor-initiating effect of the Apc(Min) mutation in the intestine.
    Cancer Res. 2009;69:4125-33.
    PubMed     Text format     Related articles    Abstract available


  40. DATTA J , Ghoshal K, Denny WA, Gamage SA, et al
    A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.
    Cancer Res. 2009;69:4277-85.
    PubMed     Text format     Related articles    Abstract available


  41. ROY HK , Turzhitsky V, Kim Y, Goldberg MJ, et al
    Association between rectal optical signatures and colonic neoplasia: potential applications for screening.
    Cancer Res. 2009;69:4476-83.
    PubMed     Text format     Related articles    Abstract available


  42. WEE S , Jagani Z, Xiang KX, Loo A, et al
    PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers.
    Cancer Res. 2009;69:4286-93.
    PubMed     Text format     Related articles    Abstract available


  43. GLOCKNER SC , Dhir M, Yi JM, McGarvey KE, et al
    Methylation of TFPI2 in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  44. GHOUL A , Serova M, Astorgues-Xerri L, Bieche I, et al
    Epithelial-to-Mesenchymal Transition and Resistance to Ingenol 3-Angelate, a Novel Protein Kinase C Modulator, in Colon Cancer Cells.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  45. KOPETZ S , Lesslie DP, Dallas NA, Park SI, et al
    Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress.
    Cancer Res. 2009;69:3842-9.
    PubMed     Text format     Related articles    Abstract available


  46. DEVAUD C , Bilhere E, Loizon S, Pitard V, et al
    Antitumor activity of gammadelta T cells reactive against cytomegalovirus-infected cells in a mouse xenograft tumor model.
    Cancer Res. 2009;69:3971-8.
    PubMed     Text format     Related articles    Abstract available


  47. REN B , Song K, Parangi S, Jin T, et al
    A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR.
    Cancer Res. 2009;69:3856-65.
    PubMed     Text format     Related articles    Abstract available


  48. STOLZ A , Vogel C, Schneider V, Ertych N, et al
    Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
    Cancer Res. 2009;69:3874-83.
    PubMed     Text format     Related articles    Abstract available


  49. NAKAI R , Iida S, Takahashi T, Tsujita T, et al
    K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells.
    Cancer Res. 2009;69:3901-9.
    PubMed     Text format     Related articles    Abstract available


    April 2009
  50. SNOOK AE , Li P, Stafford BJ, Faul EJ, et al
    Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.
    Cancer Res. 2009;69:3537-44.
    PubMed     Text format     Related articles    Abstract available


  51. KATO T , Shimono Y, Hasegawa M, Jijiwa M, et al
    Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.
    Cancer Res. 2009;69:3597-604.
    PubMed     Text format     Related articles    Abstract available


  52. KUMAR SR , Scehnet JS, Ley EJ, Singh J, et al
    Preferential Induction of EphB4 over EphB2 and Its Implication in Colorectal Cancer Progression.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  53. THANGARAJU M , Cresci GA, Liu K, Ananth S, et al
    GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.
    Cancer Res. 2009;69:2826-32.
    PubMed     Text format     Related articles    Abstract available


    March 2009
  54. LUBBE WJ , Zuzga DS, Zhou Z, Fu W, et al
    Guanylyl Cyclase C Prevents Colon Cancer Metastasis by Regulating Tumor Epithelial Cell Matrix Metalloproteinase-9.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  55. HUANG EH , Hynes MJ, Zhang T, Ginestier C, et al
    Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  56. LEROY C , Fialin C, Sirvent A, Simon V, et al
    Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells.
    Cancer Res. 2009;69:2279-86.
    PubMed     Text format     Related articles    Abstract available


  57. OZAO-CHOY J , Ma G, Kao J, Wang GX, et al
    The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies.
    Cancer Res. 2009;69:2514-22.
    PubMed     Text format     Related articles    Abstract available


  58. CAMUS M , Tosolini M, Mlecnik B, Pages F, et al
    Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  59. ARORA S , Wang XI, Keenan SM, Andaya C, et al
    Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.
    Cancer Res. 2009;69:1910-5.
    PubMed     Text format     Related articles    Abstract available


    February 2009
  60. DALLAS NA , Xia L, Fan F, Gray MJ, et al
    Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor Inhibition.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  61. SARTORE-BIANCHI A , Martini M, Molinari F, Veronese S, et al
    PIK3CA Mutations in Colorectal Cancer Are Associated with Clinical Resistance to EGFR-Targeted Monoclonal Antibodies.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  62. FIELDS AP , Calcagno SR, Krishna M, Rak S, et al
    Protein kinase Cbeta is an effective target for chemoprevention of colon cancer.
    Cancer Res. 2009;69:1643-50.
    PubMed     Text format     Related articles    Abstract available


  63. JING Y , Tong C, Zhang J, Nakamura T, et al
    Tumor and vascular targeting of a novel oncolytic measles virus retargeted against the urokinase receptor.
    Cancer Res. 2009;69:1459-68.
    PubMed     Text format     Related articles    Abstract available


  64. INDRACCOLO S , Minuzzo S, Masiero M, Pusceddu I, et al
    Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy.
    Cancer Res. 2009;69:1314-23.
    PubMed     Text format     Related articles    Abstract available


  65. STOLZENBERG-SOLOMON RZ , Hayes RB, Horst RL, Anderson KE, et al
    Serum Vitamin D and Risk of Pancreatic Cancer in the Prostate, Lung, Colorectal, and Ovarian Screening Trial.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  66. SONG S , Mazurek N, Liu C, Sun Y, et al
    Galectin-3 Mediates Nuclear {beta}-Catenin Accumulation and Wnt Signaling in Human Colon Cancer Cells by Regulation of Glycogen Synthase Kinase-3{beta} Activity.
    Cancer Res. 2009.
    PubMed     Text format     Related articles    Abstract available


  67. BRODY JR , Hucl T, Costantino CL, Eshleman JR, et al
    Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence.
    Cancer Res. 2009;69:984-91.
    PubMed     Text format     Related articles    Abstract available


  68. SATO R , Suzuki T, Katayose Y, Miura K, et al
    Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors.
    Cancer Res. 2009;69:914-22.
    PubMed     Text format     Related articles    Abstract available


    January 2009
  69. ZENG Q , Phukan S, Xu Y, Sadim M, et al
    Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.
    Cancer Res. 2009;69:678-86.
    PubMed     Text format     Related articles    Abstract available


  70. MURRAY NR , Weems J, Braun U, Leitges M, et al
    Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progression.
    Cancer Res. 2009;69:656-62.
    PubMed     Text format     Related articles    Abstract available


  71. MENG RD , Shelton CC, Li YM, Qin LX, et al
    gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
    Cancer Res. 2009;69:573-82.
    PubMed     Text format     Related articles    Abstract available


  72. LI HJ , Everts M, Yamamoto M, Curiel DT, et al
    Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors.
    Cancer Res. 2009;69:554-64.
    PubMed     Text format     Related articles    Abstract available


  73. BEERMAN TA , Gawron LS, Shin S, Shen B, et al
    C-1027, a radiomimetic enediyne anticancer drug, preferentially targets hypoxic cells.
    Cancer Res. 2009;69:593-8.
    PubMed     Text format     Related articles    Abstract available


  74. CHICHE J , Ilc K, Laferriere J, Trottier E, et al
    Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.
    Cancer Res. 2009;69:358-68.
    PubMed     Text format     Related articles    Abstract available


  75. ROECKEL N , Woerner SM, Kloor M, Yuan YP, et al
    High frequency of LMAN1 abnormalities in colorectal tumors with microsatellite instability.
    Cancer Res. 2009;69:292-9.
    PubMed     Text format     Related articles    Abstract available


    December 2008
  76. CORVER WE , Middeldorp A, ter Haar NT, Jordanova ES, et al
    Genome-wide allelic state analysis on flow-sorted tumor fractions provides an accurate measure of chromosomal aberrations.
    Cancer Res. 2008;68:10333-40.
    PubMed     Text format     Related articles    Abstract available


  77. BRAUN CJ , Zhang X, Savelyeva I, Wolff S, et al
    p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest.
    Cancer Res. 2008;68:10094-104.
    PubMed     Text format     Related articles    Abstract available


  78. CHEN GY , Shaw MH, Redondo G, Nunez G, et al
    The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis.
    Cancer Res. 2008;68:10060-7.
    PubMed     Text format     Related articles    Abstract available


  79. WANG X , Allen TD, May RJ, Lightfoot S, et al
    Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect.
    Cancer Res. 2008;68:9909-17.
    PubMed     Text format     Related articles    Abstract available


  80. MENNUNI C , Ugel S, Mori F, Cipriani B, et al
    Preventive vaccination with telomerase controls tumor growth in genetically engineered and carcinogen-induced mouse models of cancer.
    Cancer Res. 2008;68:9865-74.
    PubMed     Text format     Related articles    Abstract available


  81. BANNING A , Kipp A, Schmitmeier S, Lowinger M, et al
    Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice.
    Cancer Res. 2008;68:9746-53.
    PubMed     Text format     Related articles    Abstract available


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