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Colorectal Neoplasms

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January 2012
1. ZANETTI KA , Haznadar M, Welsh JA, Robles AI, et al
   3' UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans.
   Cancer Res. 2012.
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2. CHANG LY , Lin YC, Mahalingam J, Huang CT, et al
   Tumor-derived chemokine CCL5 enhances TGF-ss mediated killing of CD8+ T cells in colon cancer by T regulatory cells.
   Cancer Res. 2012.
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3. ZAYTSEVA YY , Rychahou PG, Gulhati P, Elliott VA, et al
   Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer.
   Cancer Res. 2012.
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   December 2011
4. YANG H , Higgins B, Kolinsky K, Packman K, et al
   Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer.
   Cancer Res. 2011.
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   November 2011
5. ZHOU Y , Tozzi F, Chen J, Fan F, et al
   Intracellular ATP levels are a pivotal determinant of chemoresistance in colon cancer cells.
   Cancer Res. 2011.
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6. BERTINI I , Cacciatore S, Jensen BV, Schou JV, et al
   Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer.
   Cancer Res. 2011.
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7. MADDALENA F , Laudiero G, Piscazzi A, Secondo A, et al
   Sorcin induces a drug-resistant phenotype in human colorectal cancer through the modulation of Ca2+ homeostasis.
   Cancer Res. 2011.
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8. BHALLA K , Hwang BJ, Dewi RE, Ou L, et al
   PGC1alpha promotes tumor growth by inducing gene expression programs supporting lipogenesis.
   Cancer Res. 2011;71:6888-98.
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9. LIU F , Liu Q, Yang D, Bollag WB, et al
   Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3.
   Cancer Res. 2011;71:6807-16.
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   October 2011
10. FELLERHOFF B , Gu S, Laumbacher B, Nerlich AG, et al
    The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer.
    Cancer Res. 2011.
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11. SHARMA V , Antonacopoulou AG, Tanaka S, Panoutsopoulos AA, et al
    Enhancement of TGF-{beta} Signaling Responses by the E3 Ubiquitin Ligase Arkadia Provides Tumor Suppression in Colorectal Cancer.
    Cancer Res. 2011;71:6438-49.
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12. KSIENZYK A , Neumann B, Nandakumar R, Finsterbusch K, et al
    IRF-1 expression is essential for natural killer cells to suppress metastasis.
    Cancer Res. 2011;71:6410-8.
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13. SOMMARIVA M , De Cecco L, De Cesare M, Sfondrini L, et al
    TLR9 agonists oppositely modulate DNA repair genes in tumor versus immune cells and enhance chemotherapy effects.
    Cancer Res. 2011;71:6382-90.
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14. KOGO R , Shimamura T, Mimori K, Kawahara K, et al
    Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.
    Cancer Res. 2011;71:6320-6.
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    September 2011
15. KIM SH , Park YY, Kim SW, Lee JS, et al
    ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression.
    Cancer Res. 2011.
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16. LIN L , Liu A, Peng Z, Lin HJ, et al
    STAT3 is necessary for proliferation and survival in colon cancer-initiating cells.
    Cancer Res. 2011.
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17. MAZUMDAR T , Devecchio J, Agyeman A, Shi T, et al
    Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
    Cancer Res. 2011;71:5904-14.
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    August 2011
18. HALAMA N , Michel S, Kloor M, Zoernig I, et al
    Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy.
    Cancer Res. 2011.
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19. BOURQUIN C , Hotz C, Noerenberg D, Voelkl A, et al
    Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance.
    Cancer Res. 2011;71:5123-33.
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20. IBRAHIM AF , Weirauch U, Thomas M, Grunweller A, et al
    MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma.
    Cancer Res. 2011;71:5214-24.
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21. MUNDY-BOSSE BL , Lesinski GB, Jaime-Ramirez AC, Benninger K, et al
    Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice.
    Cancer Res. 2011;71:5101-10.
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22. MAYES PA , Dolloff NG, Daniel CJ, Liu JJ, et al
    Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3beta and CDK1.
    Cancer Res. 2011;71:5265-75.
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    July 2011
23. 
    Correction: Effects of Carbon Ion Beam on Putative Colon Cancer Stem Cells and Its Comparison with X-rays.
    Cancer Res. 2011.
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24. GAGOU ME , Ganesh A, Thompson R, Phear G, et al
    Suppression of apoptosis by PIF1 helicase in human tumor cells.
    Cancer Res. 2011;71:4998-5008.
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25. SUZUKI H , Takatsuka S, Akashi H, Yamamoto E, et al
    Genome-wide profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer.
    Cancer Res. 2011.
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26. MURUGAN AK , Xing M
    Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene.
    Cancer Res. 2011;71:4403-11.
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27. TSUCHIYA N , Izumiya M, Ogata-Kawata H, Okamoto K, et al
    Tumor suppressor miR-22 determines p53-dependent cellular fate through post-transcriptional regulation of p21.
    Cancer Res. 2011;71:4628-39.
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    June 2011
28. 
    Correction: Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer.
    Cancer Res. 2011.
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29. OSADA T , Chen M, Yang XY, Spasojevic I, et al
    Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations.
    Cancer Res. 2011;71:4172-82.
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30. WILSON BJ , Schatton T, Zhan Q, Gasser M, et al
    ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients.
    Cancer Res. 2011.
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31. SEN A , Capitano ML, Spernyak JA, Schueckler JT, et al
    Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models.
    Cancer Res. 2011;71:3872-80.
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    May 2011
32. SAKTHIANANDESWAREN A , Christie M, D'Andreti C, Tsui C, et al
    PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis.
    Cancer Res. 2011.
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33. PADLER-KARAVANI V , Hurtado-Ziola N, Pu M, Yu H, et al
    Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer.
    Cancer Res. 2011;71:3352-63.
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34. VOISIN T , El Firar A, Fasseu M, Rouyer-Fessard C, et al
    Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis.
    Cancer Res. 2011;71:3341-51.
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    April 2011
35. ESKIOCAK U , Kim S, Ly P, Roig A, et al
    Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth.
    Cancer Res. 2011.
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36. KING C , Cuatrecasas M, Castells A, Sepulveda A, et al
    Lin28b promotes colon cancer progression and metastasis.
    Cancer Res. 2011.
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37. QIAO Y , Jiang X, Lee ST, Karuturi RK, et al
    FOXQ1 regulates epithelial-mesenchymal transition in human cancers.
    Cancer Res. 2011;71:3076-86.
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38. STAGG J , Divisekera U, Duret H, Sparwasser T, et al
    CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis.
    Cancer Res. 2011;71:2892-900.
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39. GUO J , Zheng L, Liu W, Wang X, et al
    Frequent Truncating Mutation of TFAM Induces Mitochondrial DNA Depletion and Apoptotic Resistance in Microsatellite-Unstable Colorectal Cancer.
    Cancer Res. 2011.
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40. LABONTE MJ , Wilson PM, Fazzone W, Russell J, et al
    The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.
    Cancer Res. 2011.
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41. HUANG Z , Huang S, Wang Q, Liang L, et al
    MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma.
    Cancer Res. 2011;71:2582-9.
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42. VILAR E , Bartnik CM, Stenzel SL, Raskin L, et al
    MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers.
    Cancer Res. 2011;71:2632-42.
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43. VEGRAN F , Boidot R, Michiels C, Sonveaux P, et al
    Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-kappaB/IL-8 pathway that drives tumor angiogenesis.
    Cancer Res. 2011;71:2550-60.
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    March 2011
44. CUI X , Oonishi K, Tsujii H, Yasuda T, et al
    Effects of Carbon Ion Beam on Putative Colon Cancer Stem Cells and Its Comparison with X-rays.
    Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available
    
    
    
    
45. GULHATI P , Bowen KA, Liu J, Stevens PD, et al
    mTORC1 and mTORC2 regulate EMT, motility and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
    Cancer Res. 2011.
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46. LIU X , Lai L, Wang X, Xue L, et al
    Ribonucleotide reductase small subunit M2B prognoses better survival in colorectal cancer.
    Cancer Res. 2011.
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47. KIM TH , Hur EG, Kang SJ, Kim JA, et al
    NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1alpha.
    Cancer Res. 2011;71:2260-75.
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48. HSU RY , Chan CH, Spicer JD, Rousseau MC, et al
    LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases {beta}1 Integrin-Mediated Cell Adhesion and Liver Metastasis.
    Cancer Res. 2011;71:1989-98.
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49. RISQUES RA , Lai LA, Himmetoglu C, Ebaee A, et al
    Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation.
    Cancer Res. 2011;71:1669-79.
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50. LEE AJ , Endesfelder D, Rowan AJ, Walther A, et al
    Chromosomal instability confers intrinsic multidrug resistance.
    Cancer Res. 2011;71:1858-70.
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51. PEZ F , Dayan F, Durivault J, Kaniewski B, et al
    The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
    Cancer Res. 2011;71:1647-57.
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52. FISCHER M , Yen WC, Kapoun AM, Wang M, et al
    Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.
    Cancer Res. 2011;71:1520-5.
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53. COSPER PF , Leinwand LA
    Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner.
    Cancer Res. 2011;71:1710-20.
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    February 2011
54. AL-MULLA F , Bitar MS, Al-Maghrebi M, Behbehani AI, et al
    Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3beta.
    Cancer Res. 2011;71:1334-43.
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55. BARRETT CW , Fingleton B, Williams A, Ning W, et al
    MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model.
    Cancer Res. 2011;71:1302-12.
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56. TOSOLINI M , Kirilovsky A, Mlecnik B, Fredriksen T, et al
    Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer.
    Cancer Res. 2011.
    PubMed     Text format     Related articles    Abstract available
    
    
    
    
57. PAILLAS S , Boissiere F, Bibeau F, Denouel A, et al
    Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma.
    Cancer Res. 2011;71:1041-9.
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58. VAN SCHAEYBROECK S , Kyula JN, Fenton A, Fenning CS, et al
    Oncogenic Kras promotes chemotherapy-induced growth factor shedding via ADAM17.
    Cancer Res. 2011;71:1071-80.
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59. MAZUMDAR T , DeVecchio J, Shi T, Jones J, et al
    Hedgehog signaling drives cellular survival in human colon carcinoma cells.
    Cancer Res. 2011;71:1092-102.
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60. SU CH , Zhao R, Zhang F, Qu C, et al
    14-3-3sigma exerts tumor-suppressor activity mediated by regulation of COP1 stability.
    Cancer Res. 2011;71:884-94.
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    January 2011
61. MONGROO PS , Noubissi FK, Cuatrecasas M, Kalabis J, et al
    IMP-1 displays crosstalk with K-Ras and modulates colon cancer cell survival through the novel pro-apoptotic protein CYFIP2.
    Cancer Res. 2011.
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62. PAPAGEORGIS P , Cheng K, Ozturk S, Gong Y, et al
    Smad4 Inactivation Promotes Malignancy and Drug Resistance of Colon Cancer.
    Cancer Res. 2011.
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63. YU HG , Nam JO, Miller NL, Tanjoni I, et al
    p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.
    Cancer Res. 2011;71:360-70.
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64. AOKI K , Kakizaki F, Sakashita H, Manabe T, et al
    Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1.
    Cancer Res. 2011;71:593-602.
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65. PRASAD S , Yadav VR, Ravindran J, Aggarwal BB, et al
    ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.
    Cancer Res. 2011;71:538-49.
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66. AHEARN TU , McCullough ML, Flanders WD, Long Q, et al
    A randomized clinical trial of the effects of supplemental calcium and vitamin D3 on markers of their metabolism in normal mucosa of colorectal adenoma patients.
    Cancer Res. 2011;71:413-23.
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67. BUTLER LM , Yu MC
    Fish oil exacerbates colitis in SMAD3 mice.
    Cancer Res. 2011;71:287-8.
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    December 2010
68. LIN JJ , Milhollen MA, Smith PG, Narayanan U, et al
    NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells.
    Cancer Res. 2010;70:10310-20.
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69. OKUYAMA H , Endo H, Akashika T, Kato K, et al
    Downregulation of c-MYC protein levels contributes to cancer cell survival under dual deficiency of oxygen and glucose.
    Cancer Res. 2010;70:10213-23.
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70. SHVETSOV YB , Hernandez BY, Wilkens LR, Thompson PJ, et al
    Plasma micronutrients and the acquisition and clearance of anal human papillomavirus infection: the Hawaii HPV cohort study.
    Cancer Res. 2010;70:9787-97.
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    November 2010
71. DARSIGNY M , Babeu JP, Seidman EG, Gendron FP, et al
    Hepatocyte Nuclear Factor-4{alpha} Promotes Gut Neoplasia in Mice and Protects against the Production of Reactive Oxygen Species.
    Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available
    
    
    

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