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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Colorectal Neoplasms

Free Subscription Articles published in Br J Cancer Retrieve available abstracts of 91 articles: HTML format

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July 2008
1. FIORE FD , Charbonnier F, Lefebure B, Laurent M, et al
   Clinical interest of KRAS mutation detection in blood for anti-EGFR therapies in metastatic colorectal cancer.
   Br J Cancer. 2008;.
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2. KWEEKEL DM , Gelderblom H, Van der Straaten T, Antonini NF, et al
   UGT1A1(*)28 genotype and irinotecan dosage in patients with metastatic colorectal cancer: a Dutch Colorectal Cancer Group study.
   Br J Cancer. 2008;.
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3. CARSIN AE , Sharp L, Cronin-Fenton DP, Ceilleachair AO, et al
   Inequity in colorectal cancer treatment and outcomes: a population-based study.
   Br J Cancer. 2008;.
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   June 2008
4. CAPPUZZO F , Varella-Garcia M, Finocchiaro G, Skokan M, et al
   Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients.
   Br J Cancer. 2008;.
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5. ISHIKAWA K , Kamohara Y, Tanaka F, Haraguchi N, et al
   Mitotic centromere-associated kinesin is a novel marker for prognosis and lymph node metastasis in colorectal cancer.
   Br J Cancer. 2008;98:1824-9.
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6. LANGERS AM , Sier CF, Hawinkels LJ, Kubben FJ, et al
   MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not.
   Br J Cancer. 2008;98:1820-3.
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7. CHEETHAM S , Tang MJ, Mesak F, Kennecke H, et al
   SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.
   Br J Cancer. 2008;98:1810-9.
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   May 2008
8. SHROUT J , Yousefzadeh M, Dodd A, Kirven K, et al
   beta(2)microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients.
   Br J Cancer. 2008;.
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9. LE NH , Franken P, Fodde R
   Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness.
   Br J Cancer. 2008;.
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10. KHAN OA , Ranson M, Michael M, Olver I, et al
    A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer.
    Br J Cancer. 2008;98:1614-8.
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11. BOCCI G , Falcone A, Fioravanti A, Orlandi P, et al
    Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib.
    Br J Cancer. 2008;98:1619-29.
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12. BELOBRAJDIC DP , Cosgrove LJ, Phatak A
    Elevated serum matrix metalloproteinase 9 concentration predicts the presence of colorectal neoplasia in symptomatic patients.
    Br J Cancer. 2008;98:1593.
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13. KIM MS , Jeong EG, Yoo NJ, Lee SH, et al
    Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias.
    Br J Cancer. 2008;98:1533-5.
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14. CALCAGNO AM , Fostel JM, To KK, Salcido CD, et al
    Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.
    Br J Cancer. 2008;98:1515-24.
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    April 2008
15. YOSHITAKE N , Fukui H, Yamagishi H, Sekikawa A, et al
    Expression of SDF-1alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer.
    Br J Cancer. 2008;.
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16. CALDWELL GM , Jones CE, Soon Y, Warrack R, et al
    Reorganisation of Wnt-response pathways in colorectal tumorigenesis.
    Br J Cancer. 2008;98:1437-42.
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17. VAREY AH , Rennel ES, Qiu Y, Bevan HS, et al
    VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy.
    Br J Cancer. 2008;98:1366-79.
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18. KAWAKAMI K , Ooyama A, Ruszkiewicz A, Jin M, et al
    Low expression of gamma-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype.
    Br J Cancer. 2008;.
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19. BRULAND O , Fluge O, Immervoll H, Balteskard L, et al
    Gene expression reveals two distinct groups of anal carcinomas with clinical implications.
    Br J Cancer. 2008;98:1264-73.
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20. ILES S , Gollins S, Susnerwala S, Haylock B, et al
    Irinotecan+5-fluorouracil with concomitant pre-operative radiotherapy in locally advanced non-resectable rectal cancer: a phase I/II study.
    Br J Cancer. 2008;98:1210-6.
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21. KOEBERLE D , Burkhard R, von Moos R, Winterhalder R, et al
    Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer.
    Br J Cancer. 2008;98:1204-9.
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    March 2008
22. ALLEGRINI G , Falcone A, Fioravanti A, Barletta MT, et al
    A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.
    Br J Cancer. 2008;.
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23. PITTMAN AM , Broderick P, Sullivan K, Fielding S, et al
    CASP8 variants D302H and -652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population.
    Br J Cancer. 2008;.
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24. CONAGHAN PJ , Ashraf SQ, Tytherleigh MG, Wilding JL, et al
    Targeted killing of colorectal cancer cell lines by a humanised IgG1 monoclonal antibody that binds to membrane-bound carcinoembryonic antigen.
    Br J Cancer. 2008;.
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25. HIRIPI E , Bermejo JL, Sundquist J, Hemminki K, et al
    Association of colorectal adenoma with other malignancies in Swedish families.
    Br J Cancer. 2008;98:997-1000.
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26. YAMADA Y , Tahara M, Miya T, Satoh T, et al
    Phase I/II study of oxaliplatin with oral S-1 as first-line therapy for patients with metastatic colorectal cancer.
    Br J Cancer. 2008;.
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    February 2008
27. SOBHANI I , Tiret E, Lebtahi R, Aparicio T, et al
    Early detection of recurrence by (18)FDG-PET in the follow-up of patients with colorectal cancer.
    Br J Cancer. 2008;.
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28. FREDERIKSEN BL , Osler M, Harling H, Jorgensen T, et al
    Social inequalities in stage at diagnosis of rectal but not in colonic cancer: a nationwide study.
    Br J Cancer. 2008;98:668-73.
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29. MOUNIER CM , Wendum D, Greenspan E, Flejou JF, et al
    Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate.
    Br J Cancer. 2008;98:587-95.
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30. STEBBING J , Harrison M, Glynne-Jones R, Bridgewater J, et al
    A phase II study to determine the ability of gefitinib to reverse fluoropyrimidine resistance in metastatic colorectal cancer (the INFORM study).
    Br J Cancer. 2008;.
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    January 2008
31. HAMILTON W , Lancashire R, Sharp D, Peters TJ, et al
    The importance of anaemia in diagnosing colorectal cancer: a case-control study using electronic primary care records.
    Br J Cancer. 2008;98:323-7.
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32. ZLOBEC I , Vuong T, Compton CC, Lugli A, et al
    Combined analysis of VEGF and EGFR predicts complete tumour response in rectal cancer treated with preoperative radiotherapy.
    Br J Cancer. 2008;98:450-6.
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33. NEGRI FV , Campanini N, Camisa R, Pucci F, et al
    Biological predictive factors in rectal cancer treated with preoperative radiotherapy or radiochemotherapy.
    Br J Cancer. 2008;98:143-7.
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34. LAGADEC P , Griessinger E, Nawrot MP, Fenouille N, et al
    Pharmacological targeting of NF-kappaB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells.
    Br J Cancer. 2008;.
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    December 2007
35. OIKONOMOU E , Kothonidis K, Taoufik E, Probert E, et al
    Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL induced apoptosis in vitro and in vivo.
    Br J Cancer. 2007;97:1716.
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36. TIROSH B , Daniel-Carmi V, Carmon L, Paz A, et al
    '1-8 interferon inducible gene family': putative colon carcinoma-associated antigens.
    Br J Cancer. 2007;97:1655-63.
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37. WANG X , Hershman DL, Abrams JA, Feingold D, et al
    Predictors of survival after hepatic resection among patients with colorectal liver metastasis.
    Br J Cancer. 2007;97:1606-12.
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38. DUNCAN R , Carpenter B, Main LC, Telfer C, et al
    Characterisation and protein expression profiling of annexins in colorectal cancer.
    Br J Cancer. 2007;.
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39. MITCHELL E , Macdonald S, Campbell NC, Weller D, et al
    Influences on pre-hospital delay in the diagnosis of colorectal cancer: a systematic review.
    Br J Cancer. 2007;.
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40. CASCINU S , Berardi R, Salvagni S, Beretta GD, et al
    A combination of gefitinib and FOLFOX-4 as first-line treatment in advanced colorectal cancer patients. A GISCAD multicentre phase II study including a biological analysis of EGFR overexpression, amplification and NF-kB activation.
    Br J Cancer. 2007;.
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41. KABAT GC , Miller AB, Jain M, Rohan TE, et al
    A cohort study of dietary iron and heme iron intake and risk of colorectal cancer in women.
    Br J Cancer. 2007;97:1600.
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42. SIENA S , Peeters M, Van Cutsem E, Humblet Y, et al
    Association of progression-free survival with patient-reported outcomes and survival: results from a randomised phase 3 trial of panitumumab.
    Br J Cancer. 2007;97:1469-74.
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43. WEI LH , Baumann H, Tracy E, Wang Y, et al
    Interleukin-6 trans signalling enhances photodynamic therapy by modulating cell cycling.
    Br J Cancer. 2007;97:1513-22.
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    November 2007
44. WELLER D , Coleman D, Robertson R, Butler P, et al
    The UK colorectal cancer screening pilot: results of the second round of screening in England.
    Br J Cancer. 2007;.
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45. DAHM F , Bielawska A, Nocito A, Georgiev P, et al
    Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice.
    Br J Cancer. 2007;.
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46. GOBBI PG , Valentino F, Berardi E, Tronconi C, et al
    New insights into the role of age and carcinoembryonic antigen in the prognosis of colorectal cancer.
    Br J Cancer. 2007;.
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47. CRAVEN I , Crellin A, Cooper R, Melcher A, et al
    Preoperative radiotherapy combined with 5 days per week capecitabine chemotherapy in locally advanced rectal cancer.
    Br J Cancer. 2007;97:1333-7.
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48. HUBNER RA , Liu JF, Sellick GS, Logan RF, et al
    Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma.
    Br J Cancer. 2007;97:1449-56.
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49. HARADA K , Hiraoka S, Kato J, Horii J, et al
    Genetic and epigenetic alterations of Ras signalling pathway in colorectal neoplasia: analysis based on tumour clinicopathological features.
    Br J Cancer. 2007;97:1425-31.
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50. HOFFMEISTER M , Raum E, Winter J, Chang-Claude J, et al
    Hormone replacement therapy, body mass, and the risk of colorectal cancer among postmenopausal women from Germany.
    Br J Cancer. 2007;.
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    October 2007
51. SHASTRI YM , Stein JM
    New faecal tests for colorectal cancer screening: is tumour pyruvate kinase M2 one of the options?
    Br J Cancer. 2007;.
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52. HAUG U , Brenner H
    Reply: New faecal tests for colorectal cancer screening: is tumour pyruvate kinase M2 one of the options?
    Br J Cancer. 2007;.
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53. FRATTINI M , Saletti P, Romagnani E, Martin V, et al
    PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients.
    Br J Cancer. 2007;97:1139-45.
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54. MAUGHAN NJ , Morris E, Forman D, Quirke P, et al
    The validity of the Royal College of Pathologists' colorectal cancer minimum dataset within a population.
    Br J Cancer. 2007;.
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55. LEITCH EF , Chakrabarti M, Crozier JE, McKee RF, et al
    Comparison of the prognostic value of selected markers of the systemic inflammatory response in patients with colorectal cancer.
    Br J Cancer. 2007;.
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56. HURST NG , Stocken DD, Wilson S, Keh C, et al
    Elevated serum matrix metalloproteinase 9 (MMP-9) concentration predicts the presence of colorectal neoplasia in symptomatic patients.
    Br J Cancer. 2007;97:971-7.
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57. PARET C , Hildebrand D, Weitz J, Kopp-Schneider A, et al
    C4.4A as a candidate marker in the diagnosis of colorectal cancer.
    Br J Cancer. 2007;.
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    September 2007
58. BARONE C , Nuzzo G, Cassano A, Basso M, et al
    Final analysis of colorectal cancer patients treated with irinotecan and 5-fluorouracil plus folinic acid neoadjuvant chemotherapy for unresectable liver metastases.
    Br J Cancer. 2007;.
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59. OSTERLUND P , Ruotsalainen T, Korpela R, Saxelin M, et al
    Lactobacillus supplementation for diarrhoea related to chemotherapy of colorectal cancer: a randomised study.
    Br J Cancer. 2007;.
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60. PENEGAR S , Wood W, Lubbe S, Chandler I, et al
    National study of colorectal cancer genetics.
    Br J Cancer. 2007;.
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61. SCHIPPINGER W , Samonigg H, Schaberl-Moser R, Greil R, et al
    A prospective randomised phase III trial of adjuvant chemotherapy with 5-fluorouracil and leucovorin in patients with stage II colon cancer.
    Br J Cancer. 2007;.
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62. PIETERSE AH , Stiggelbout AM, Baas-Thijssen MC, van de Velde CJ, et al
    Benefit from preoperative radiotherapy in rectal cancer treatment: disease-free patients' and oncologists' preferences.
    Br J Cancer. 2007;97:717-24.
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63. FANCIULLINO R , Giacometti S, Mercier C, Aubert C, et al
    In vitro and in vivo reversal of resistance to 5-fluorouracil in colorectal cancer cells with a novel stealth double-liposomal formulation.
    Br J Cancer. 2007;.
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    August 2007
64. GUO X , Evans TR, Somanath S, Armesilla AL, et al
    In vitro evaluation of cancer-specific NF-kappaB-CEA enhancer-promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines.
    Br J Cancer. 2007;.
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    July 2007
65. DELORD JP , Bennouna J, Artru P, Perrier H, et al
    Phase II study of UFT with leucovorin and irinotecan (TEGAFIRI): first-line therapy for metastatic colorectal cancer.
    Br J Cancer. 2007;.
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66. OTANI T , Iwasaki M, Sasazuki S, Inoue M, et al
    Plasma vitamin D and risk of colorectal cancer: the Japan Public Health Center-Based Prospective Study.
    Br J Cancer. 2007;.
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67. SCARTOZZI M , Bearzi I, Berardi R, Mandolesi A, et al
    Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options.
    Br J Cancer. 2007;97:92-7.
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    June 2007
68. EL-EMIR E , Dearling JL, Huhalov A, Robson MP, et al
    Characterisation and radioimmunotherapy of L19-SIP, an anti-angiogenic antibody against the extra domain B of fibronectin, in colorectal tumour models.
    Br J Cancer. 2007;96:1862-70.
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69. LIU J , Harada H, Ogura M, Shibata T, et al
    Adenovirus-mediated hypoxia-targeting cytosine deaminase gene therapy enhances radiotherapy in tumour xenografts.
    Br J Cancer. 2007;96:1871-8.
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70. OIKONOMOU E , Kothonidis K, Zografos G, Nasioulas G, et al
    Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL-induced apoptosis in vitro and in vivo.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available
    
    
    
71. KABAT GC , Miller AB, Jain M, Rohan TE, et al
    A cohort study of dietary iron and heme iron intake and risk of colorectal cancer in women.
    Br J Cancer. 2007;.
    PubMed     Related articles    Abstract available
    
    
    
72. THIRLWELL C , Howarth KM, Segditsas S, Guerra G, et al
    Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
    Br J Cancer. 2007;96:1729-34.
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73. BOREL M , Degoul F, Communal Y, Mounetou E, et al
    N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.
    Br J Cancer. 2007;96:1684-91.
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74. ALTIERI A , Hemminki K
    Number of siblings and the risk of solid tumours: a nation-wide study.
    Br J Cancer. 2007;96:1755-9.
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    May 2007
75. MANSILLA F , Birkenkamp-Demtroder K, Kruhoffer M, Sorensen FB, et al
    Differential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroups.
    Br J Cancer. 2007;.
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76. OVERBEEK LI , Kets CM, Hebeda KM, Bodmer D, et al
    Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer.
    Br J Cancer. 2007;96:1605-12.
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77. ANDERSON JA , Grabowska AM, Watson SA
    PTHrP increases transcriptional activity of the integrin subunit alpha5.
    Br J Cancer. 2007;96:1394-403.
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    April 2007
78. CASTIGLIONE G , Visioli CB, Ciatto S, Grazzini G, et al
    Sensitivity of latex agglutination faecal occult blood test in the Florence District population-based colorectal cancer screening programme.
    Br J Cancer. 2007;.
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79. SAKAMOTO J , Hamada C, Yoshida S, Kodaira S, et al
    An individual patient data meta-analysis of adjuvant therapy with uracil-tegafur (UFT) in patients with curatively resected rectal cancer.
    Br J Cancer. 2007;96:1170-7.
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80. ALMOND J , Ralston S
    The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer.
    Br J Cancer. 2007;.
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81. WARD SE
    Reply: The clinical and economic benefits of capecitabine and tegafur with uracil in metastatic colorectal cancer.
    Br J Cancer. 2007;.
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82. NEHLS O , Okech T, Hsieh CJ, Enzinger T, et al
    Studies on p53, BAX and Bcl-2 protein expression and microsatellite instability in stage III (UICC) colon cancer treated by adjuvant chemotherapy: major prognostic impact of proapoptotic BAX.
    Br J Cancer. 2007;.
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83. PUPPA G , Maisonneuve P, Sonzogni A, Masullo M, et al
    Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma.
    Br J Cancer. 2007;96:1118-26.
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84. WELSH FK , Tilney HS, Tekkis PP, John TG, et al
    Safe liver resection following chemotherapy for colorectal metastases is a matter of timing.
    Br J Cancer. 2007;96:1037-42.
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85. HAUG U , Rothenbacher D, Wente MN, Seiler CM, et al
    Tumour M2-PK as a stool marker for colorectal cancer: comparative analysis in a large sample of unselected older adults vs colorectal cancer patients.
    Br J Cancer. 2007;.
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    March 2007
86. WILLEKE F , Horisberger K, Kraus-Tiefenbacher U, Wenz F, et al
    A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer.
    Br J Cancer. 2007;96:912-7.
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87. DI FIORE F , Blanchard F, Charbonnier F, Le Pessot F, et al
    Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy.
    Br J Cancer. 2007;.
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88. STANLEY M
    Prophylactic HPV vaccines: prospects for eliminating ano-genital cancer.
    Br J Cancer. 2007;.
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89. NERI B , Pantaleo P, Giommoni E, Grifoni R, et al
    Oxaliplatin, 5-fluorouracil/leucovorin and epirubicin as first-line treatment in advanced gastric carcinoma: a phase II study.
    Br J Cancer. 2007;.
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90. GIOVANNETTI E , Backus HH, Wouters D, Ferreira CG, et al
    Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels.
    Br J Cancer. 2007;96:769-75.
    PubMed     Related articles    Abstract available
    
    
    February 2007
91. GLYNNE-JONES R , Falk S, Maughan TS, Meadows HM, et al
    A phase I/II study of irinotecan when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group Study.
    Br J Cancer. 2007;96:551-8.
    PubMed     Related articles    Abstract available
    
    

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