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Articles published in Ann Oncol

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Single Articles


    April 2018
  1. APARICIO T, Bouche O, Taieb J, Maillard E, et al
    Bevacizumab+chemotherapy versus chemotherapy alone in elderly patients with untreated metastatic colorectal cancer: a randomized phase II trial-PRODIGE 20 study results.
    Ann Oncol. 2018 Apr 30. pii: 4990353. doi: 10.1093.
    PubMed     Text format    


  2. SANTOS C, Sanz-Pamplona R, Salazar R
    RET-fusions: a novel paradigm in colorectal cancer.
    Ann Oncol. 2018 Apr 10. pii: 4965879. doi: 10.1093.
    PubMed     Text format    


  3. SIENA S, Sartore-Bianchi A, Marsoni S, Hurwitz HI, et al
    Targeting the human epidermal growth factor receptor 2 (HER2) oncogene in colorectal cancer.
    Ann Oncol. 2018 Apr 6. pii: 4962457. doi: 10.1093.
    PubMed     Text format     Abstract available


  4. MASUISHI T, Taniguchi H, Sugiyama K, Kato K, et al
    Eribulin in BRAF V600E mutant metastatic colorectal cancer: Case series and potential rationale.
    Ann Oncol. 2018 Apr 4. pii: 4959907. doi: 10.1093.
    PubMed     Text format    


    March 2018
  5. MALVEZZI M, Carioli G, Bertuccio P, Boffetta P, et al
    European cancer mortality predictions for the year 2018 with focus on colorectal cancer.
    Ann Oncol. 2018 Mar 19. pii: 4935197. doi: 10.1093.
    PubMed     Text format     Abstract available


  6. MONTAGUT C, Tsui DW, Diaz LA Jr.
    Detection of somatic RAS mutations in circulating tumor DNA from metastatic colorectal cancer patients: are we ready for clinical use?
    Ann Oncol. 2018 Mar 14. pii: 4937227. doi: 10.1093.
    PubMed     Text format    


  7. SMEBY J, Sveen A, Merok MA, Danielsen SA, et al
    CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer.
    Ann Oncol. 2018 Mar 5. pii: 4922418. doi: 10.1093.
    PubMed     Text format     Abstract available


    February 2018
  8. ARNOLD D, Prager GW, Quintela A, Stein A, et al
    Beyond Second-Line Therapy in Patients With Metastatic Colorectal Cancer: A Systematic Review.
    Ann Oncol. 2018 Feb 14. pii: 4857261. doi: 10.1093.
    PubMed     Text format     Abstract available


  9. BACHET JB, Bouche O, Taieb J, Dubreuil O, et al
    RAS mutation analysis in circulating tumor DNA from patients with metastatic colorectal cancer: the AGEO RASANC prospective multicenter study.
    Ann Oncol. 2018 Feb 9. pii: 4846852. doi: 10.1093.
    PubMed     Text format     Abstract available


  10. CARR PR, Alwers E, Bienert S, Weberpals J, et al
    Lifestyle factors and risk of sporadic colorectal cancer by microsatellite instability status: A systematic review and meta-analyses.
    Ann Oncol. 2018 Feb 9. pii: 4846850. doi: 10.1093.
    PubMed     Text format     Abstract available


  11. SOBRERO A, Grothey A, Iveson T, Labianca R, et al
    The hard road to data interpretation: three or six months of adjuvant chemotherapy for patients with stage III colon cancer?
    Ann Oncol. 2018 Feb 9. pii: 4846853. doi: 10.1093.
    PubMed     Text format     Abstract available


    January 2018
  12. SOBHANI I, Itti E, Luciani A, Baumgaertner I, et al
    Colorectal Cancer (CRC) Monitoring by Six-Monthly 18FDG-PET/CT: An Open-Label Multicentre Randomised Trial.
    Ann Oncol. 2018 Jan 22. pii: 4819113. doi: 10.1093.
    PubMed     Text format     Abstract available


  13. CARMELIET P, Li X, Treps L, Conradi LC, et al
    RAISEing VEGF-D's importance as predictive biomarker for ramucirumab in metastatic colorectal cancer patients.
    Ann Oncol. 2018 Jan 19. pii: 4817343. doi: 10.1093.
    PubMed     Text format    


  14. PARK JH, McMillan DC
    Outcome in colorectal cancer - tumour, stroma and so much more.
    Ann Oncol. 2018 Jan 8. pii: 4792956. doi: 10.1093.
    PubMed     Text format    


  15. DELL'AQUILA E, Cremolini C, Zeppola T, Lonardi S, et al
    Prognostic and predictive role of neutrophil/lymphocytes ratio in metastatic colorectal cancer: a retrospective analysis of the TRIBE study by GONO.
    Ann Oncol. 2018 Jan 8. pii: 4793700. doi: 10.1093.
    PubMed     Text format     Abstract available


    December 2017
  16. KHOSROW-KHAVAR F, Yin H, Barkun A, Bouganim N, et al
    Aromatase Inhibitors and the Risk of Colorectal Cancer in Post-Menopausal Women with Breast Cancer.
    Ann Oncol. 2017 Dec 27. pii: 4779926. doi: 10.1093.
    PubMed     Text format     Abstract available


  17. DANIELSEN HE, Hveem TS, Domingo E, Pradhan M, et al
    Prognostic markers for colorectal cancer; estimating ploidy and stroma.
    Ann Oncol. 2017 Dec 27. pii: 4779924. doi: 10.1093.
    PubMed     Text format     Abstract available


  18. YAMADA Y, Denda T, Gamoh M, Iwanaga I, et al
    S-1 and irinotecan plus bevacizumab versus mFOLFOX6 or CapeOX plus bevacizumab as first-line treatment in patients with metastatic colorectal cancer (TRICOLORE): a randomized, open-label, phase 3, non-inferiority trial.
    Ann Oncol. 2017 Dec 27. pii: 4779925. doi: 10.1093.
    PubMed     Text format     Abstract available


  19. GONG J, Tian J, Lou J, Wang X, et al
    A polymorphic MYC response element in KBTBD11 influences colorectal cancer risk, especially in interaction with a MYC regulated SNP rs6983267.
    Ann Oncol. 2017 Dec 18. pii: 4756051. doi: 10.1093.
    PubMed     Text format     Abstract available


  20. ORDONEZ-ME JM, Walter V, Schottker B, Jenab M, et al
    Impact of prediagnostic smoking and smoking cessation on colorectal cancer prognosis: a meta-analysis of individual patient data from cohorts within the CHANCES consortium.
    Ann Oncol. 2017 Dec 13. pii: 4735153. doi: 10.1093.
    PubMed     Text format     Abstract available


  21. TABERNERO J, Hozak RR, Yoshino T, Cohn AL, et al
    Analysis of Angiogenesis Biomarkers for Ramucirumab Efficacy in Patients with Metastatic Colorectal Cancer from RAISE, a Global, Randomized, Double-Blind, Phase III Study.
    Ann Oncol. 2017 Dec 7. pii: 4708229. doi: 10.1093.
    PubMed     Text format     Abstract available


    November 2017
  22. YOSHINO T, Arnold D, Taniguchi H, Pentheroudakis G, et al
    Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer; A JSMO - ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS.
    Ann Oncol. 2017 Nov 16. doi: 10.1093.
    PubMed     Text format     Abstract available


  23. ABAD A, Martinez-Balibrea E, Vieitez JM, Orduna VA, et al
    Genotype-based selection of treatment for patients with advanced colorectal cancer (SETICC): a pharmacogenetic-based randomized phase II trial.
    Ann Oncol. 2017 Nov 14. doi: 10.1093.
    PubMed     Text format     Abstract available


  24. DIENSTMANN R, Guinney J
    Reply to the letter to the editor 'Including lynch syndrome in personalized prognostication and follow-up of stage II and III colon cancer' by Sciallero et al.
    Ann Oncol. 2017;28:2889-2890.
    PubMed     Text format    


    October 2017
  25. OVERMAN M, Adam L, Raghav K, Wang J, et al
    Phase II study of nab-paclitaxel in refractory small bowel adenocarcinoma and CpG island methylator phenotype (CIMP)-high colorectal cancer.
    Ann Oncol. 2017 Oct 23. doi: 10.1093.
    PubMed     Text format     Abstract available


  26. TARAZONA N, Cervantes A
    Liquid biopsy: another tool towards tailored therapy in colorectal cancer.
    Ann Oncol. 2017 Oct 10. doi: 10.1093.
    PubMed     Text format    


  27. SCIALLERO S, Battistuzzi L, Varesco L
    Including Lynch syndrome in personalized prognostication and follow-up of stage II and III colon cancer.
    Ann Oncol. 2017;28:2620-2621.
    PubMed     Text format    


  28. CASADEI GARDINI A, Valgiusti M, Passardi A, Frassineti GL, et al
    Treatment of squamous cell carcinoma of the anal canal (SCCA): a new era?
    Ann Oncol. 2017;28:2620.
    PubMed     Text format    


    September 2017
  29. APARICIO T, Bouche O, Taieb J, Maillard E, et al
    Bevacizumab + chemotherapy versus chemotherapy alone in elderly patients with untreated metastatic colorectal cancer: a randomized phase II trial - PRODIGE 20 study results.
    Ann Oncol. 2017 Sep 28. doi: 10.1093.
    PubMed     Text format     Abstract available


  30. CREMOLINI C, Morano F, Moretto R, Berenato R, et al
    Negative hyper-selection of metastatic colorectal cancer patients for anti-EGFR monoclonal antibodies: the PRESSING case-control study.
    Ann Oncol. 2017 Sep 25. doi: 10.1093.
    PubMed     Text format     Abstract available


  31. GARCIA-FONCILLAS J, Alba E, Aranda E, Diaz-Rubio E, et al
    Incorporating BEAMing technology as a liquid biopsy into clinical practice for the management of colorectal cancer patients: an expert taskforce review.
    Ann Oncol. 2017 Sep 4. doi: 10.1093.
    PubMed     Text format     Abstract available


  32. SIENA S, Sartore-Bianchi A, Garcia-Carbonero R, Karthaus M, et al
    Dynamic Molecular Analysis and Clinical Correlates of Tumor Evolution Within a Phase 2 Trial of Panitumumab-Based Therapy in Metastatic Colorectal Cancer.
    Ann Oncol. 2017 Sep 4. doi: 10.1093.
    PubMed     Text format     Abstract available


  33. SOBRERO A, Damiani A
    Maintenance therapy in advanced colorectal cancer, yes or no? Ask the laboratory.
    Ann Oncol. 2017;28:2043-2044.
    PubMed     Text format    


  34. WEI Q, Ye Z, Zhong X, Li L, et al
    Multiregion whole-exome sequencing of matched primary and metastatic tumors revealed genomic heterogeneity and suggested polyclonal seeding in colorectal cancer metastasis.
    Ann Oncol. 2017;28:2135-2141.
    PubMed     Text format     Abstract available


  35. GOEY KKH, Elias SG, van Tinteren H, Lacle MM, et al
    Maintenance treatment with capecitabine and bevacizumab versus observation in metastatic colorectal cancer: updated results and molecular subgroup analyses of the phase 3 CAIRO3 study.
    Ann Oncol. 2017;28:2128-2134.
    PubMed     Text format     Abstract available


    August 2017
  36. NORMANNO N, Esposito Abate R, Lambiase M, Forgione L, et al
    RAS testing of liquid biopsy correlates with the outcome of metastatic colorectal cancer patients treated with first-line FOLFIRI plus cetuximab in the CAPRI-GOIM trial.
    Ann Oncol. 2017 Aug 7. doi: 10.1093.
    PubMed     Text format     Abstract available


  37. BERGER MD, Stintzing S, Heinemann V, Yang D, et al
    Impact of genetic variations in the MAPK signaling pathway on outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI and bevacizumab: data from FIRE-3 and TRIBE trials.
    Ann Oncol. 2017 Aug 2. doi: 10.1093.
    PubMed     Text format     Abstract available


  38. WHITE NM, Maher CA
    The potential use of lncRNAs found in the 8q24 region as biomarkers for colon cancer.
    Ann Oncol. 2017;28:1688-1689.
    PubMed     Text format    


  39. OZAWA T, Matsuyama T, Toiyama Y, Takahashi N, et al
    CCAT1 and CCAT2 long noncoding RNAs, located within the 8q.24.21 'gene desert', serve as important prognostic biomarkers in colorectal cancer.
    Ann Oncol. 2017;28:1882-1888.
    PubMed     Text format     Abstract available


    July 2017
  40. SANZ-GARCIA E, Argiles G, Elez E, Tabernero J, et al
    BRAF mutant Colorectal Cancer: prognosis, treatment and new perspectives.
    Ann Oncol. 2017 Jul 24. doi: 10.1093.
    PubMed     Text format     Abstract available


    June 2017
  41. SCHLESINGER S, Aleksandrova K, Abar L, Vieria AR, et al
    Adult weight gain and colorectal adenomas-a systematic review and meta-analysis.
    Ann Oncol. 2017;28:1217-1229.
    PubMed     Text format     Abstract available


    May 2017
  42. WILLIS JA, Vilar E
    Refining Prognosis in Early-Stage Colorectal Cancer: One or multiple genes at a time?
    Ann Oncol. 2017 May 26. doi: 10.1093.
    PubMed     Text format    


  43. SUNAKAWA Y, Tsuji A, Fujii M, Ichikawa W, et al
    No benefit from the addition of anti-EGFR antibody in all right-sided metastatic colorectal cancer?
    Ann Oncol. 2017 May 5. doi: 10.1093.
    PubMed     Text format    


  44. DIENSTMANN R, Mason MJ, Sinicrope FA, Phipps AI, et al
    Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.
    Ann Oncol. 2017;28:1023-1031.
    PubMed     Text format     Abstract available


  45. SUENAGA M, Schirripa M, Cao S, Zhang W, et al
    Genetic variants of DNA repair-related genes predict efficacy of TAS-102 in patients with refractory metastatic colorectal cancer.
    Ann Oncol. 2017;28:1015-1022.
    PubMed     Text format     Abstract available


  46. AUCLIN E, Zaanan A, Vernerey D, Douard R, et al
    Subgroups and prognostication in stage III colon cancer: future perspectives for adjuvant therapy.
    Ann Oncol. 2017;28:958-968.
    PubMed     Text format     Abstract available


  47. OTT PA, Piha-Paul SA, Munster P, Pishvaian MJ, et al
    Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with recurrent carcinoma of the anal canal.
    Ann Oncol. 2017;28:1036-1041.
    PubMed     Text format     Abstract available


    April 2017
  48. ROHR UP, Herrmann P, Ilm K, Zhang H, et al
    Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies.
    Ann Oncol. 2017 Apr 28. doi: 10.1093.
    PubMed     Text format     Abstract available


  49. BOECKX N, Koukakis R, Op de Beeck K, Rolfo C, et al
    Primary tumor sidedness has an impact on prognosis and treatment outcome in metastatic colorectal cancer: results from two randomized first-line panitumumab studies.
    Ann Oncol. 2017 Apr 25. doi: 10.1093.
    PubMed     Text format     Abstract available


  50. BONNETAIN F, Borg C, Adams RR, Ajani JA, et al
    How health-related quality of life assessment should be used in advanced colorectal cancer clinical trials.
    Ann Oncol. 2017 Apr 18. doi: 10.1093.
    PubMed     Text format     Abstract available


  51. VIDAL J, Muinelo L, Dalmases A, Jones F, et al
    Plasma ctDNA RAS mutation analysis for the diagnosis and treatment monitoring of metastatic colorectal cancer patients.
    Ann Oncol. 2017 Apr 13. doi: 10.1093.
    PubMed     Text format     Abstract available


  52. ARNOLD D, Lueza B, Douillard JY, Peeters M, et al
    Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomised trials.
    Ann Oncol. 2017 Apr 12. doi: 10.1093.
    PubMed     Text format     Abstract available


  53. VIEIRA AR, Abar L, Chan D, Vingeliene S, et al
    Foods and beverages and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, an update of the evidence of the WCRF-AICR Continuous Update Project.
    Ann Oncol. 2017 Apr 12. doi: 10.1093.
    PubMed     Text format     Abstract available


  54. KWAKMAN JJ, Simkens LH, van Rooijen JM, van de Wouw AJ, et al
    Randomised phase III trial of S-1 versus capecitabine in the first-line treatment of metastatic colorectal cancer: SALTO study by the Dutch Colorectal Cancer Group.
    Ann Oncol. 2017 Apr 5. doi: 10.1093.
    PubMed     Text format     Abstract available


  55. FONT R, Espinas JA, Layos L, Martinez Villacampa M, et al
    Adherence to capecitabine in preoperative treatment of stage II and III rectal cancer: do we need to worry?
    Ann Oncol. 2017;28:831-835.
    PubMed     Text format     Abstract available


  56. BUDHATHOKI S, Iwasaki M, Yamaji T, Yamamoto H, et al
    Association of plasma concentrations of branched-chain amino acids with risk of colorectal adenoma in a large Japanese population.
    Ann Oncol. 2017;28:818-823.
    PubMed     Text format     Abstract available


    March 2017
  57. MA B, King AD, Leung L, Wang K, et al
    Identifying an early indicator of drug efficacy in patients with metastatic colorectal cancer - a prospective evaluation of circulating tumor cells, 18F-fluorodeoxyglucose positron-emission tomography and the RECIST criteria.
    Ann Oncol. 2017 Mar 30. doi: 10.1093.
    PubMed     Text format     Abstract available


  58. ROSPO G, Corti G, Crisafulli G, Novara L, et al
    Tracking colorectal cancer evolution in time and space.
    Ann Oncol. 2017 Mar 24. doi: 10.1093.
    PubMed     Text format    


  59. SIRAVEGNA G, Sartore-Bianchi A, Mussolin B, Cassingena A, et al
    Tracking a CAD-ALK gene rearrangement in urine and blood of a colorectal cancer patient treated with an ALK inhibitor.
    Ann Oncol. 2017 Mar 24. doi: 10.1093.
    PubMed     Text format     Abstract available


  60. GRASSELLI J, Elez E, Caratu G, Matito J, et al
    Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer.
    Ann Oncol. 2017 Mar 20. doi: 10.1093.
    PubMed     Text format     Abstract available


  61. FUCHS MA, Yuan C, Sato K, Niedzwiecki D, et al
    Predicted Vitamin D Status and Colon Cancer Recurrence and Mortality in CALGB 89803 (Alliance).
    Ann Oncol. 2017 Mar 15. doi: 10.1093.
    PubMed     Text format     Abstract available


  62. ROMBOUTS AJM, Hugen N, Elferink MAG, Feuth T, et al
    Incidence of second tumors after treatment with or without radiation for rectal cancer.
    Ann Oncol. 2017;28:535-540.
    PubMed     Text format     Abstract available


    February 2017
  63. PILATI C, Taieb J, Balogoun R, Marisa L, et al
    CDX2 prognostic value in stage II/III resected colon cancer is related to CMS classification.
    Ann Oncol. 2017 Feb 27. doi: 10.1093.
    PubMed     Text format     Abstract available


  64. LONARDI S, Sobrero A, Rosati G, Di Bartolomeo M, et al
    Phase III trial comparing 3-6 months of adjuvant FOLFOX4/XELOX in stage II-III colon cancer: safety and compliance in the TOSCA trial.
    Ann Oncol. 2017 Feb 23. doi: 10.1093.
    PubMed     Text format    


  65. LOTE H, Spiteri I, Ermini L, Vatsiou A, et al
    Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer.
    Ann Oncol. 2017 Feb 23. doi: 10.1093.
    PubMed     Text format     Abstract available


  66. SANTINI D, Vincenzi B, Addeo R, Garufi C, et al
    Cetuximab rechallenge in metastatic colorectal cancer patients: how to come away from acquired resistance?
    Ann Oncol. 2017 Feb 21. doi: 10.1093.
    PubMed     Text format    


  67. DIENSTMANN R, Mason MJ, Sinicrope FA, Phipps AI, et al
    Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.
    Ann Oncol. 2017 Feb 9. doi: 10.1093.
    PubMed     Text format    


  68. SUENAGA M, Schirripa M, Cao S, Zhang W, et al
    Genetic variants of DNA repair-related genes predict efficacy of TAS-102 in patients with refractory metastatic colorectal cancer.
    Ann Oncol. 2017 Feb 9. doi: 10.1093.
    PubMed     Text format    


  69. PATEL UB, Brown G, Machado I, Santos-Cores J, et al
    MRI assessment and outcomes in patients receiving neoadjuvant chemotherapy only for primary rectal cancer: long-term results from the GEMCAD 0801 trial.
    Ann Oncol. 2017;28:344-353.
    PubMed     Text format     Abstract available


  70. YANG TO, Cairns BJ, Reeves GK, Green J, et al
    Cancer risk among 21st century blood transfusion recipients.
    Ann Oncol. 2017;28:393-399.
    PubMed     Text format     Abstract available


  71. GLYNNE-JONES R
    Adding extra dimensions in rectal cancer theory.
    Ann Oncol. 2017;28:198-200.
    PubMed     Text format    


    January 2017
  72. AUCLIN E, Zaanan A, Vernerey D, Douard R, et al
    Subgroups and Prognostication in Stage III Colon Cancer: Future Perspectives for Adjuvant Therapy.
    Ann Oncol. 2017 Jan 27. pii: mdx030. doi: 10.1093.
    PubMed     Text format     Abstract available


  73. POWELL MA
    Immunohistochemistry to determine mismatch repair-deficiency in endometrial cancer: the appropriate standard.
    Ann Oncol. 2017;28:9-10.
    PubMed     Text format    


    December 2016
  74. TAIEB J, Balogoun R, Le Malicot K, Tabernero J, et al
    Adjuvant FOLFOX +/- cetuximab in full RAS and BRAF wildtype stage III colon cancer patients.
    Ann Oncol. 2016 Dec 28. pii: mdw687. doi: 10.1093.
    PubMed     Text format     Abstract available


  75. SCHUURHUIZEN CS, Braamse AM, Konings IR, Sprangers MA, et al
    Does severe toxicity affect global quality of life in patients with metastatic colorectal cancer during palliative systemic treatment? A systematic review.
    Ann Oncol. 2016 Dec 19. pii: mdw617. doi: 10.1093.
    PubMed     Text format     Abstract available


  76. SELIGMANN JF, Fisher D, Smith CG, Richman SD, et al
    Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: Analysis from 2530 patients in randomised clinical trials.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


    November 2016
  77. PIETRANTONIO F, Miceli R, Rimassa L, Lonardi S, et al
    Estimating 12-weeks death probability in patients with refractory metastatic colorectal cancer: the Colon Life nomogram.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  78. SWETS M, Breugom AJ, Gelderblom H, van de Velde CJ, et al
    Should rectal cancer located 10-15cm from the anal verge be defined as colon cancer.
    Ann Oncol. 2016.
    PubMed     Text format    


    October 2016
  79. QUIDDE J, Hegewisch-Becker S, Graeven U, Lerchenmuller CA, et al
    Quality of life assessment in patients with metastatic colorectal cancer receiving maintenance therapy after first-line induction treatment: a preplanned analysis of the phase III AIO KRK 0207 trial.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  80. STELLOO E, Jansen AM, Osse EM, Nout RA, et al
    Practical guidance for mismatch repair-deficiency testing in endometrial cancer.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  81. MOORE M, Gill S, Asmis T, Berry S, et al
    Randomized phase II study of modified FOLFOX-6 in combination with ramucirumab or icrucumab as second-line therapy in patients with metastatic colorectal cancer after disease progression on first-line irinotecan-based therapy.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  82. DEENEN MJ, Meulendijks D
    Recommendation on testing for dihydropyrimidine dehydrogenase deficiency in the ESMO consensus guidelines for the management of patients with metastatic colorectal cancer.
    Ann Oncol. 2016.
    PubMed     Text format    


    September 2016

  83. appendix 5: Metastatic colorectal cancer (2): eUpdate published online August 2016 (www.esmo.org/Guidelines/Gastrointestinal-Cancers).
    Ann Oncol. 2016;27.
    PubMed     Text format    



  84. appendix 4: Metastatic colorectal cancer (1): eUpdate published online September 2016 (www.esmo.org/Guidelines/Gastrointestinal-Cancers).
    Ann Oncol. 2016;27.
    PubMed     Text format    


    August 2016
  85. LONARDI S, Sobrero A, Rosati G, Di Bartolomeo M, et al
    Phase III trial comparing 3 to 6 months of adjuvant FOLFOX4/XELOX in stage II-III colon cancer: safety and compliance in the TOSCA trial.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  86. IMAOKA H, Toiyama Y, Fujikawa H, Hiro J, et al
    Circulating microRNA-1290 as a novel diagnostic and prognostic biomarker in human colorectal cancer.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


    July 2016
  87. VARDY JL, Dhillon HM, Pond GR, Renton C, et al
    Fatigue in people with localized colorectal cancer who do and do not receive chemotherapy: a longitudinal prospective study.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  88. MEI Z, Duan C, Li C, Cui L, et al
    Prognostic role of tumor PIK3CAmutation in colorectal cancer: a systematic review and meta-analysis.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  89. VAN CUTSEM E, Cervantes A, Adam R, Sobrero A, et al
    ESMO consensus guidelines for the management of patients with metastatic colorectal cancer.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


    June 2016
  90. MODEST DP, Ricard I, Heinemann V, Hegewisch-Becker S, et al
    Outcome according to KRAS-, NRAS- and BRAF-mutation as well as KRAS mutation variants - pooled analysis of five randomized trials in metastatic colorectal cancer by the AIO colorectal cancer study group.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  91. SOBRERO A
    A tribute to biologics in advanced colorectal cancer treatment.
    Ann Oncol. 2016.
    PubMed     Text format    


    May 2016
  92. MICHL M, Stintzing S, Fischer von Weikersthal L, Decker T, et al
    CEA response is associated with tumor response and survival in patients with KRAS exon 2 wild-type and extended RAS wild-type metastatic colorectal cancer receiving first-line FOLFIRI plus cetuximab or bevacizumab (FIRE-3 trial).
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  93. REN HG, Luu HN, Cai H, Xiang YB, et al
    Oral health and risk of colorectal cancer: results from three cohort studies and a meta-analysis.
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  94. LUO HY, Xu RH
    Reply to "Safety profile of capecitabine as maintenance treatment after XELOX or FOLFOX in metastatic colorectal cancer patients" by C. Cremolini et al.
    Ann Oncol. 2016.
    PubMed     Text format    


  95. YAMAZAKI K, Nagase M, Tamagawa H, Ueda S, et al
    Randomized phase III study of bevacizumab plus FOLFIRI and bevacizumab plus mFOLFOX6 as first-line treatment for patients with metastatic colorectal cancer (WJOG4407G).
    Ann Oncol. 2016.
    PubMed     Text format     Abstract available


  96. CREMOLINI C, Moretto R, Masi G, Falcone A, et al
    Safety profile of capecitabine as maintenance treatment after XELOX or FOLFOX in metastatic colorectal cancer patients.
    Ann Oncol. 2016.
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