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Neoplasms of the CNS

Free Subscription Articles published in Oncogene Retrieve available abstracts of 68 articles: HTML format Text format

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May 2012
1. WEILER M , Pfenning PN, Thiepold AL, Blaes J, et al
   Suppression of proinvasive RGS4 by mTOR inhibition optimizes glioma treatment.
   Oncogene. 2012 May 7. doi: 10.1038/onc.2012.
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   April 2012
2. GALEANO F , Rossetti C, Tomaselli S, Cifaldi L, et al
   ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis.
   Oncogene. 2012 Apr 23. doi: 10.1038/onc.2012.
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3. GALAVOTTI S , Bartesaghi S, Faccenda D, Shaked-Rabi M, et al
   The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells.
   Oncogene. 2012 Apr 23. doi: 10.1038/onc.2012.
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4. WANG Y , Moncayo G, Morin P Jr, Xue G, et al
   Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme.
   Oncogene. 2012 Apr 2. doi: 10.1038/onc.2012.
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5. WAGNER L , Marschall V, Karl S, Cristofanon S, et al
   Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-kappaB-dependent manner.
   Oncogene. 2012 Apr 2. doi: 10.1038/onc.2012.
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   March 2012
6. QI Q , He K, Liu X, Pham C, et al
   Disrupting the PIKE-A/Akt interaction inhibits glioblastoma cell survival, migration, invasion and colony formation.
   Oncogene. 2012 Mar 26. doi: 10.1038/onc.2012.
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   February 2012
7. KESANAKURTI D , Chetty C, Dinh DH, Gujrati M, et al
   Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with alpha5beta1 integrin in glioma.
   Oncogene. 2012 Feb 20. doi: 10.1038/onc.2012.
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8. WANG SD , Rath P, Lal B, Richard JP, et al
   EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase.
   Oncogene. 2012 Feb 6. doi: 10.1038/onc.2012.
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   January 2012
9. BANGERT A , Cristofanon S, Eckhardt I, Abhari BA, et al
   Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP.
   Oncogene. 2012 Jan 23. doi: 10.1038/onc.2011.
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10. YOON CH , Kim MJ, Kim RK, Lim EJ, et al
    c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells.
    Oncogene. 2012 Jan 16. doi: 10.1038/onc.2011.
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11. FASSL A , Tagscherer KE, Richter J, Berriel Diaz M, et al
    Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.
    Oncogene. 2012 Jan 16. doi: 10.1038/onc.2011.
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    December 2011
12. ROGERS AE , Le JP, Sather S, Pernu BM, et al
    Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology.
    Oncogene. 2011 Dec 19. doi: 10.1038/onc.2011.
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13. DITTMANN LM , Danner A, Gronych J, Wolter M, et al
    Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro.
    Oncogene. 2011 Dec 12. doi: 10.1038/onc.2011.
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14. BONAVIA R , Inda MM, Vandenberg S, Cheng SY, et al
    EGFRvIII promotes glioma angiogenesis and growth through the NF-kappaB, interleukin-8 pathway.
    Oncogene. 2011 Dec 5. doi: 10.1038/onc.2011.
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15. WU S , Lin Y, Xu D, Chen J, et al
    MiR-135a functions as a selective killer of malignant glioma.
    Oncogene. 2011 Dec 5. doi: 10.1038/onc.2011.
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    November 2011
16. WANKA C , Brucker DP, Bahr O, Ronellenfitsch M, et al
    Synthesis of cytochrome c oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death.
    Oncogene. 2011 Nov 28. doi: 10.1038/onc.2011.
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17. TANORI M , Pasquali E, Leonardi S, Giardullo P, et al
    Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum.
    Oncogene. 2011;30:4740-9.
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18. MANCUSO M , Pasquali E, Leonardi S, Rebessi S, et al
    Role of connexin43 and ATP in long-range bystander radiation damage and oncogenesis in vivo.
    Oncogene. 2011;30:4601-8.
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19. GOIDTS V , Bageritz J, Puccio L, Nakata S, et al
    RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival.
    Oncogene. 2011 Nov 7. doi: 10.1038/onc.2011.
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    October 2011
20. NATSUME A , Kato T, Kinjo S, Enomoto A, et al
    Girdin maintains the stemness of glioblastoma stem cells.
    Oncogene. 2011 Oct 24. doi: 10.1038/onc.2011.
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21. JUN HJ , Acquaviva J, Chi D, Lessard J, et al
    Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme.
    Oncogene. 2011 Oct 24. doi: 10.1038/onc.2011.
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    September 2011
22. FENG H , Liu KW, Guo P, Zhang P, et al
    Dynamin 2 mediates PDGFRalpha-SHP-2-promoted glioblastoma growth and invasion.
    Oncogene. 2011 Sep 26. doi: 10.1038/onc.2011.
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23. JONES TS , Holland EC
    Standard of care therapy for malignant glioma and its effect on tumor and stromal cells.
    Oncogene. 2011 Sep 12. doi: 10.1038/onc.2011.
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    August 2011
24. PAPAGIANNAKOPOULOS T , Friedmann-Morvinski D, Neveu P, Dugas JC, et al
    Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases.
    Oncogene. 2011 Aug 29. doi: 10.1038/onc.2011.
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25. FERNANDEZ-L A , Squatrito M, Northcott P, Awan A, et al
    Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation.
    Oncogene. 2011 Aug 29. doi: 10.1038/onc.2011.
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26. JENNEWEIN C , Karl S, Baumann B, Micheau O, et al
    Identification of a novel pro-apoptotic role of NF-kappaB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells.
    Oncogene. 2011 Aug 8. doi: 10.1038/onc.2011.
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27. MOLINA JR , Agarwal NK, Morales FC, Hayashi Y, et al
    PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma.
    Oncogene. 2011 Aug 1. doi: 10.1038/onc.2011.
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    July 2011
28. HAAPA-PAANANEN S , Kiviluoto S, Waltari M, Puputti M, et al
    HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation.
    Oncogene. 2011 Jul 25. doi: 10.1038/onc.2011.
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29. QUINTAVALLE C , Garofalo M, Zanca C, Romano G, et al
    miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPmu
    Oncogene. 2011 Jul 11. doi: 10.1038/onc.2011.
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30. ARIAS A , Lame MW, Santarelli L, Hen R, et al
    Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas.
    Oncogene. 2011 Jul 4. doi: 10.1038/onc.2011.
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    June 2011
31. LI X , Law JW, Lee AY
    Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton.
    Oncogene. 2011 Jun 27. doi: 10.1038/onc.2011.
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32. WANG X , Venugopal C, Manoranjan B, McFarlane N, et al
    Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells.
    Oncogene. 2011 Jun 20. doi: 10.1038/onc.2011.
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    May 2011
33. POSCHL J , Lorenz A, Hartmann W, von Bueren AO, et al
    Expression of BARHL1 in medulloblastoma is associated with prolonged survival in mice and humans.
    Oncogene. 2011.
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34. HACKER S , Karl S, Mader I, Cristofanon S, et al
    Histone deacetylase inhibitors prime medulloblastoma cells for chemotherapy-induced apoptosis by enhancing p53-dependent Bax activation.
    Oncogene. 2011;30:2275-81.
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    April 2011
35. MESSINA S , Frati L, Leonetti C, Zuchegna C, et al
    Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas.
    Oncogene. 2011.
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    March 2011
36. NOGUEIRA L , Ruiz-Ontanon P, Vazquez-Barquero A, Lafarga M, et al
    Blockade of the NFkappaB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo.
    Oncogene. 2011.
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37. YING M , Wang S, Sang Y, Sun P, et al
    Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition.
    Oncogene. 2011.
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    February 2011
38. FIASCHETTI G , Castelletti D, Zoller S, Schramm A, et al
    Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma.
    Oncogene. 2011.
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    January 2011
39. KWAK HJ , Kim YJ, Chun KR, Woo YM, et al
    Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas.
    Oncogene. 2011.
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40. BHATIA B , Hsieh M, Kenney AM, Nahle Z, et al
    Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.
    Oncogene. 2011;30:504.
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41. BENDER A , Opel D, Naumann I, Kappler R, et al
    PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis.
    Oncogene. 2011;30:494-503.
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42. KALAMARIDES M , Stemmer-Rachamimov AO, Niwa-Kawakita M, Chareyre F, et al
    Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes.
    Oncogene. 2011.
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    December 2010
43. YEN KE , Bittinger MA, Su SM, Fantin VR, et al
    Cancer-associated IDH mutations: biomarker and therapeutic opportunities.
    Oncogene. 2010;29:6409-17.
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    November 2010
44. PONG WW , Gutmann DH
    The ecology of brain tumors: lessons learned from neurofibromatosis-1.
    Oncogene. 2010.
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45. ROBINSON JP , Vanbrocklin MW, Lastwika KJ, McKinney AJ, et al
    Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo.
    Oncogene. 2010.
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    October 2010
46. PINES G , Huang PH, Zwang Y, White FM, et al
    EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism.
    Oncogene. 2010;29:5850-60.
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47. HILL VK , Underhill-Day N, Krex D, Robel K, et al
    Epigenetic inactivation of the RASSF10 candidate tumor suppressor gene is a frequent and an early event in gliomagenesis.
    Oncogene. 2010.
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48. BHATIA B , Hsieh M, Kenney AM, Nahle Z, et al
    Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.
    Oncogene. 2010.
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    August 2010
49. SAVASKAN NE , Seufert S, Hauke J, Trankle C, et al
    Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.
    Oncogene. 2010.
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50. LE PU , Angers-Loustau A, de Oliveira RM, Ajlan A, et al
    DRR drives brain cancer invasion by regulating cytoskeletal-focal adhesion dynamics.
    Oncogene. 2010;29:4636-47.
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51. BRALTEN LB , Gravendeel AM, Kloosterhof NK, Sacchetti A, et al
    The CASPR2 cell adhesion molecule functions as a tumor suppressor gene in glioma.
    Oncogene. 2010.
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52. OLSEN BB , Issinger OG, Guerra B
    Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells.
    Oncogene. 2010.
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53. TCHAICHA JH , Mobley AK, Hossain MG, Aldape KD, et al
    A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis.
    Oncogene. 2010;29:4460-72.
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54. HERRERO-GONZALEZ S , Gangoso E, Giaume C, Naus CC, et al
    Connexin43 inhibits the oncogenic activity of c-Src in C6 glioma cells.
    Oncogene. 2010.
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    July 2010
55. LAU KM , Chan QK, Pang JC, Li KK, et al
    Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion.
    Oncogene. 2010.
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    June 2010
56. BARTKOVA J , Hamerlik P, Stockhausen MT, Ehrmann J, et al
    Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas.
    Oncogene. 2010.
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    May 2010
57. AZIZ MH , Hafeez BB, Sand JM, Pierce DB, et al
    Protein kinase Cvarepsilon mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression, and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2, and ERK1/2).
    Oncogene. 2010;29:3100-9.
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58. KAPOOR GS , O'Rourke DM
    SIRPalpha1 receptors interfere with the EGFRvIII signalosome to inhibit glioblastoma cell transformation and migration.
    Oncogene. 2010.
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59. KUZONTKOSKI PM , Mulligan-Kehoe MJ, Harris BT, Israel MA, et al
    Inhibitor of DNA binding-4 promotes angiogenesis and growth of glioblastoma multiforme by elevating matrix GLA levels.
    Oncogene. 2010.
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60. HATTON BA , Villavicencio EH, Pritchard J, Leblanc M, et al
    Notch signaling is not essential in sonic hedgehog-activated medulloblastoma.
    Oncogene. 2010.
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    April 2010
61. JI P , Smith SM, Wang Y, Jiang R, et al
    Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP.
    Oncogene. 2010.
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62. JULIAN E , Dave RK, Robson JP, Hallahan AR, et al
    Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma.
    Oncogene. 2010.
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63. SERRANO J , Fernandez AP, Martinez-Murillo R, Martinez A, et al
    High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease.
    Oncogene. 2010;29:2165-71.
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64. LEE CC , Jan HJ, Lai JH, Ma HI, et al
    Nodal promotes growth and invasion in human gliomas.
    Oncogene. 2010.
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    March 2010
65. SEE WL , Miller JP, Squatrito M, Holland E, et al
    Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas.
    Oncogene. 2010;29:1720-31.
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66. VAN EEKELEN M , Sasportas LS, Kasmieh R, Yip S, et al
    Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors.
    Oncogene. 2010.
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67. ERNST A , Campos B, Meier J, Devens F, et al
    De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures.
    Oncogene. 2010.
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68. KONGKHAM PN , Northcott PA, Croul SE, Smith CA, et al
    The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma.
    Oncogene. 2010.
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