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	Amedeo Prize 2008 The 21 Finalists

Neoplasms of the CNS

Free Subscription Articles published in Clin Cancer Res Retrieve available abstracts of 103 articles: HTML format

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May 2008
1. SPENCE AM , Muzi M, Swanson KR, O'Sullivan F, et al
   Regional Hypoxia in Glioblastoma Multiforme Quantified with [18F]Fluoromisonidazole Positron Emission Tomography before Radiotherapy: Correlation with Time to Progression and Survival.
   Clin Cancer Res. 2008;14:2623-30.
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   April 2008
2. SMITH ER , Zurakowski D, Saad A, Scott RM, et al
   Urinary biomarkers predict brain tumor presence and response to therapy.
   Clin Cancer Res. 2008;14:2378-86.
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3. ULLRICH R , Backes H, Li H, Kracht L, et al
   Glioma proliferation as assessed by 3'-fluoro-3'-deoxy-L-thymidine positron emission tomography in patients with newly diagnosed high-grade glioma.
   Clin Cancer Res. 2008;14:2049-55.
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   March 2008
4. GILG AG , Tye SL, Tolliver LB, Wheeler WG, et al
   Targeting hyaluronan interactions in malignant gliomas and their drug-resistant multipotent progenitors.
   Clin Cancer Res. 2008;14:1804-13.
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5. HUSZTHY PC , Goplen D, Thorsen F, Immervoll H, et al
   Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma.
   Clin Cancer Res. 2008;14:1571-80.
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   February 2008
6. GURURANGAN S , Turner CD, Stewart CF, O'Shaughnessy M, et al
   Phase I Trial of VNP40101M (Cloretazine) in Children with Recurrent Brain Tumors: A Pediatric Brain Tumor Consortium Study.
   Clin Cancer Res. 2008;14:1124-30.
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7. ROSSI A , Caracciolo V, Russo G, Reiss K, et al
   Medulloblastoma: From Molecular Pathology to Therapy.
   Clin Cancer Res. 2008;14:971-976.
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8. YANG W , Wu G, Barth RF, Swindall MR, et al
   Molecular Targeting and Treatment of Composite EGFR and EGFRvIII-Positive Gliomas Using Boronated Monoclonal Antibodies.
   Clin Cancer Res. 2008;14:883-91.
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   January 2008
9. YOSHIMOTO K , Dang J, Zhu S, Nathanson D, et al
   Development of a Real-time RT-PCR Assay for Detecting EGFRvIII in Glioblastoma Samples.
   Clin Cancer Res. 2008;14:488-493.
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10. GOW CH , Chien CR, Chang YL, Chiu YH, et al
    Radiotherapy in lung adenocarcinoma with brain metastases: effects of activating epidermal growth factor receptor mutations on clinical response.
    Clin Cancer Res. 2008;14:162-8.
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11. HUTTERER M , Knyazev P, Abate A, Reschke M, et al
    Axl and growth arrest specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme.
    Clin Cancer Res. 2008;14:130-8.
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12. ZEPPERNICK F , Ahmadi R, Campos B, Dictus C, et al
    Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients.
    Clin Cancer Res. 2008;14:123-9.
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13. KORSISAARI N , Ross J, Wu X, Kowanetz M, et al
    Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1.
    Clin Cancer Res. 2008;14:249-58.
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14. WYKOSKY J , Gibo DM, Stanton C, Debinski W, et al
    Interleukin-13 receptor alpha 2, EphA2, and Fos-related antigen 1 as molecular denominators of high-grade astrocytomas and specific targets for combinatorial therapy.
    Clin Cancer Res. 2008;14:199-208.
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    December 2007
15. LAMFERS ML , Idema S, Bosscher L, Heukelom S, et al
    Differential Effects of Combined Ad5-{Delta}24RGD and Radiation Therapy in In vitro versus In vivo Models of Malignant Glioma.
    Clin Cancer Res. 2007;13:7451-7458.
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16. KUHN JG , Chang SM, Wen PY, Cloughesy TF, et al
    Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.
    Clin Cancer Res. 2007;13:7401-6.
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17. SHIRAHATA M , Iwao-Koizumi K, Saito S, Ueno N, et al
    Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis.
    Clin Cancer Res. 2007;13:7341-56.
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18. JIANG X , Lu X, Liu R, Zhang F, et al
    HLA Tetramer Based Artificial Antigen-Presenting Cells Efficiently Stimulate CTLs Specific for Malignant Glioma.
    Clin Cancer Res. 2007;13:7329-34.
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19. LIU C , Sarkaria JN, Petell CA, Paraskevakou G, et al
    Combination of Measles Virus Virotherapy and Radiation Therapy Has Synergistic Activity in the Treatment of Glioblastoma Multiforme.
    Clin Cancer Res. 2007;13:7155-7165.
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20. LOGHIN ME , Prados MD, Wen P, Junck L, et al
    Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
    Clin Cancer Res. 2007;13:7133-8.
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21. LO KC , Ma C, Bundy BN, Pomeroy SL, et al
    Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma.
    Clin Cancer Res. 2007;13:7022-8.
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22. MANGIOLA A , Lama G, Giannitelli C, De Bonis P, et al
    Stem Cell Marker Nestin and c-Jun NH2-Terminal Kinases in Tumor and Peritumor Areas of Glioblastoma Multiforme: Possible Prognostic Implications.
    Clin Cancer Res. 2007;13:6970-6977.
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    November 2007
23. MILETIC H , Fischer YH, Giroglou T, Rueger MA, et al
    Normal Brain Cells Contribute to the Bystander Effect in Suicide Gene Therapy of Malignant Glioma.
    Clin Cancer Res. 2007;13:6761-6768.
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24. BRONISCER A , Gururangan S, Macdonald TJ, Goldman S, et al
    Phase I Trial of Single-Dose Temozolomide and Continuous Administration of O6-Benzylguanine in Children with Brain Tumors: a Pediatric Brain Tumor Consortium Report.
    Clin Cancer Res. 2007;13:6712-6718.
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25. AOKI H , Yokoyama T, Fujiwara K, Tari AM, et al
    Phosphorylated Pak1 Level in the Cytoplasm Correlates with Shorter Survival Time in Patients with Glioblastoma.
    Clin Cancer Res. 2007;13:6603-6609.
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26. KOSCHNY R , Sykora J, Walczak H, Ganten TM, et al
    Bortezomib-Mediated Up-Regulation of TRAIL-R1 and TRAIL-R2 Is Not Necessary for but Contributes to Sensitization of Primary Human Glioma Cells to TRAIL.
    Clin Cancer Res. 2007;13:6541-6542.
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27. HAQUE T , Faury D, Albrecht S, Lopez-Aguilar E, et al
    Gene Expression Profiling from Formalin-Fixed Paraffin-Embedded Tumors of Pediatric Glioblastoma.
    Clin Cancer Res. 2007;13:6284-6292.
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28. KYRITSIS AP , Tachmazoglou F, Rao JS, Puduvalli VK, et al
    Bortezomib sensitizes human astrocytoma cells to tumor necrosis factor related apoptosis-inducing ligand induced apoptosis.
    Clin Cancer Res. 2007;13:6540-1.
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    October 2007
29. YAMINI B , Yu X, Pytel P, Galanopoulos N, et al
    Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
    Clin Cancer Res. 2007;13:6217-23.
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30. IKEGAKI N , Gotoh T, Kung B, Riceberg JS, et al
    De novo identification of MIZ-1 (ZBTB17) encoding a MYC-interacting zinc-finger protein as a new favorable neuroblastoma gene.
    Clin Cancer Res. 2007;13:6001-9.
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    August 2007
31. ROUSSEAU J , Boudou C, Barth RF, Balosso J, et al
    Enhanced Survival and Cure of F98 Glioma Bearing Rats following Intracerebral Delivery of Carboplatin in Combination with Photon Irradiation.
    Clin Cancer Res. 2007;.
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    July 2007
32. ZHOU Q , Guo P, Kruh GD, Vicini P, et al
    Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition.
    Clin Cancer Res. 2007;13:4271-9.
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33. GONDI CS , Lakka SS, Dinh DH, Olivero WC, et al
    Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.
    Clin Cancer Res. 2007;13:4051-60.
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34. KOBAYASHI T , Masumoto J, Tada T, Nomiyama T, et al
    Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas.
    Clin Cancer Res. 2007;13:3868-74.
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    June 2007
35. EWEND MG , Brem S, Gilbert M, Goodkin R, et al
    Treatment of single brain metastasis with resection, intracavity carmustine polymer wafers, and radiation therapy is safe and provides excellent local control.
    Clin Cancer Res. 2007;13:3637-41.
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36. GEORGE J , Gondi CS, Dinh DH, Gujrati M, et al
    Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis.
    Clin Cancer Res. 2007;13:3507-17.
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37. BARNETT JA , Urbauer DL, Murray GI, Fuller GN, et al
    Cytochrome P450 1B1 expression in glial cell tumors: an immunotherapeutic target.
    Clin Cancer Res. 2007;13:3559-67.
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38. KOSCHNY R , Holland H, Sykora J, Haas TL, et al
    Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
    Clin Cancer Res. 2007;13:3403-12.
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    May 2007
39. MCCONVILLE P , Hambardzumyan D, Moody JB, Leopold WR, et al
    Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma.
    Clin Cancer Res. 2007;13:2897-904.
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40. RUTKOWSKI S , von Bueren A, von Hoff K, Hartmann W, et al
    Prognostic Relevance of Clinical and Biological Risk Factors in Childhood Medulloblastoma: Results of Patients Treated in the Prospective Multicenter Trial HIT'91.
    Clin Cancer Res. 2007;13:2651-7.
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41. COSTA BM , Ferreira P, Costa S, Canedo P, et al
    Association between Functional EGF+61 Polymorphism and Glioma Risk.
    Clin Cancer Res. 2007;13:2621-6.
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42. EOLI M , Menghi F, Bruzzone MG, De Simone T, et al
    Methylation of O6-Methylguanine DNA Methyltransferase and Loss of Heterozygosity on 19q and/or 17p Are Overlapping Features of Secondary Glioblastomas with Prolonged Survival.
    Clin Cancer Res. 2007;13:2606-13.
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43. CARLSON MR , Pope WB, Horvath S, Braunstein JG, et al
    Relationship between Survival and Edema in Malignant Gliomas: Role of Vascular Endothelial Growth Factor and Neuronal Pentraxin 2.
    Clin Cancer Res. 2007;13:2592-2598.
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44. FEDELE M , De Martino I, Pivonello R, Ciarmiello A, et al
    SOM230, a new somatostatin analogue, is highly effective in the therapy of growth hormone/prolactin-secreting pituitary adenomas.
    Clin Cancer Res. 2007;13:2738-44.
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    April 2007
45. GILLESPIE DL , Whang K, Ragel BT, Flynn JR, et al
    Silencing of Hypoxia Inducible Factor-1{alpha} by RNA Interference Attenuates Human Glioma Cell Growth In vivo.
    Clin Cancer Res. 2007;13:2441-8.
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46. ZHOU H , Miki R, Eeva M, Fike FM, et al
    Reciprocal Regulation of SOCS 1 and SOCS3 Enhances Resistance to Ionizing Radiation in Glioblastoma Multiforme.
    Clin Cancer Res. 2007;13:2344-2353.
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47. SOUSSAIN C , Muldoon LL, Varallyay C, Jahnke K, et al
    Characterization and magnetic resonance imaging of a rat model of human B-cell central nervous system lymphoma.
    Clin Cancer Res. 2007;13:2504-11.
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48. LI L , Gondi CS, Dinh DH, Olivero WC, et al
    Transfection with Anti-p65 Intrabody Suppresses Invasion and Angiogenesis in Glioma Cells by Blocking Nuclear Factor-{kappa}B Transcriptional Activity.
    Clin Cancer Res. 2007;13:2178-90.
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49. FECCI PE , Ochiai H, Mitchell DA, Grossi PM, et al
    Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function.
    Clin Cancer Res. 2007;13:2158-67.
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50. CAHILL DP , Levine KK, Betensky RA, Codd PJ, et al
    Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment.
    Clin Cancer Res. 2007;13:2038-45.
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    March 2007
51. JOHNS TG , Perera RM, Vernes SC, Vitali AA, et al
    The Efficacy of Epidermal Growth Factor Receptor-Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization.
    Clin Cancer Res. 2007;13:1911-1925.
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52. PATEL RR , Mehta MP
    Targeted therapy for brain metastases: improving the therapeutic ratio.
    Clin Cancer Res. 2007;13:1675-83.
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53. LIN NU , Winer EP
    Brain Metastases: The HER2 Paradigm.
    Clin Cancer Res. 2007;13:1648-55.
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54. MAYER M
    A patient perspective on brain metastases in breast cancer.
    Clin Cancer Res. 2007;13:1623-4.
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55. DEEKEN JF , Loscher W
    The blood-brain barrier and cancer: transporters, treatment, and Trojan horses.
    Clin Cancer Res. 2007;13:1663-74.
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56. PALMIERI D , Chambers AF, Felding-Habermann B, Huang S, et al
    The biology of metastasis to a sanctuary site.
    Clin Cancer Res. 2007;13:1656-62.
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57. ARAGON-CHING JB , Zujewski JA
    CNS metastasis: an old problem in a new guise.
    Clin Cancer Res. 2007;13:1644-7.
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58. BRONISCER A , Panetta JC, O'Shaughnessy M, Fraga C, et al
    Plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite OSI-420.
    Clin Cancer Res. 2007;13:1511-5.
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59. MARTIN DT , Gendron RL, Jarzembowski JA, Perry A, et al
    Tubedown expression correlates with the differentiation status and aggressiveness of neuroblastic tumors.
    Clin Cancer Res. 2007;13:1480-7.
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60. SCHRAMM A , Vandesompele J, Schulte JH, Dreesmann S, et al
    Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome.
    Clin Cancer Res. 2007;13:1459-65.
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61. LAVON I , Zrihan D, Zelikovitch B, Fellig Y, et al
    Longitudinal assessment of genetic and epigenetic markers in oligodendrogliomas.
    Clin Cancer Res. 2007;13:1429-37.
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    February 2007
62. WU G , Yang W, Barth RF, Kawabata S, et al
    Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab.
    Clin Cancer Res. 2007;13:1260-8.
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63. VREDENBURGH JJ , Desjardins A, Herndon JE 2nd, Dowell JM, et al
    Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma.
    Clin Cancer Res. 2007;13:1253-9.
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64. YIN D , Ong JM, Hu J, Desmond JC, et al
    Suberoylanilide Hydroxamic Acid, a Histone Deacetylase Inhibitor: Effects on Gene Expression and Growth of Glioma Cells In vitro and In vivo.
    Clin Cancer Res. 2007;13:1045-52.
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    January 2007
65. BOBOLA MS , Varadarajan S, Smith NW, Goff RD, et al
    Human glioma cell sensitivity to the sequence-specific alkylating agent methyl-lexitropsin.
    Clin Cancer Res. 2007;13:612-20.
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66. ZHANG JG , Eguchi J, Kruse CA, Gomez GG, et al
    Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
    Clin Cancer Res. 2007;13:566-75.
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67. MELLINGHOFF IK , Cloughesy TF, Mischel PS
    PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors.
    Clin Cancer Res. 2007;13.
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68. WRENSCH M , McMillan A, Wiencke J, Wiemels J, et al
    Nonsynonymous coding single-nucleotide polymorphisms spanning the genome in relation to glioblastoma survival and age at diagnosis.
    Clin Cancer Res. 2007;13:197-205.
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69. YOO H , Baia GS, Smith JS, McDermott MW, et al
    Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas.
    Clin Cancer Res. 2007;13:68-75.
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    December 2006
70. LEARN CA , Fecci PE, Schmittling RJ, Xie W, et al
    Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T Cells in Patients with Malignant Glioma Reveals Differential Expression of the Immunologic Transcriptome Compared with T Cells from Healthy Volunteers.
    Clin Cancer Res. 2006;12:7306-15.
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71. NICHOLAS MK , Lukas RV, Jafri NF, Faoro L, et al
    Epidermal growth factor receptor-mediated signal transduction in the development and therapy of gliomas.
    Clin Cancer Res. 2006;12:7261-70.
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72. WEBER A , Starke S, Bergmann E, Christiansen H, et al
    The coamplification pattern of the MYCN amplicon is an invariable attribute of most MYCN-amplified human neuroblastomas.
    Clin Cancer Res. 2006;12:7316-21.
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73. ROSELL R , Taron M, Reguart N, Isla D, et al
    Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway.
    Clin Cancer Res. 2006;12:7222-31.
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74. YAMAMOTO J , Yamamoto S, Hirano T, Li S, et al
    Monitoring of singlet oxygen is useful for predicting the photodynamic effects in the treatment for experimental glioma.
    Clin Cancer Res. 2006;12:7132-9.
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    November 2006
75. REDJAL N , Chan JA, Segal RA, Kung AL, et al
    CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.
    Clin Cancer Res. 2006;12:6765-71.
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76. REDDY GR , Bhojani MS, McConville P, Moody J, et al
    Vascular targeted nanoparticles for imaging and treatment of brain tumors.
    Clin Cancer Res. 2006;12:6677-86.
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77. LIU TC , Zhang T, Fukuhara H, Kuroda T, et al
    Dominant-Negative Fibroblast Growth Factor Receptor Expression Enhances Antitumoral Potency of Oncolytic Herpes Simplex Virus in Neural Tumors.
    Clin Cancer Res. 2006;12:6791-6799.
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78. TANNO B , Mancini C, Vitali R, Mancuso M, et al
    Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo.
    Clin Cancer Res. 2006;12:6772-80.
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79. TSUDA N , Ishiyama S, Li Y, Ioannides CG, et al
    Synthetic MicroRNA Designed to Target Glioma-Associated Antigen 1 Transcription Factor Inhibits Division and Induces Late Apoptosis in Pancreatic Tumor Cells.
    Clin Cancer Res. 2006;12:6557-6564.
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80. KHWAJA FW , Duke-Cohan JS, Brat DJ, Van Meir EG, et al
    Attractin Is Elevated in the Cerebrospinal Fluid of Patients with Malignant Astrocytoma and Mediates Glioma Cell Migration.
    Clin Cancer Res. 2006;12:6331-6336.
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    October 2006
81. MARTENS T , Schmidt NO, Eckerich C, Fillbrandt R, et al
    A Novel One-Armed Anti-c-Met Antibody Inhibits Glioblastoma Growth In vivo.
    Clin Cancer Res. 2006;12:6144-52.
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82. FINE RL , Chen J, Balmaceda C, Bruce JN, et al
    Randomized study of Paclitaxel and tamoxifen deposition into human brain tumors: implications for the treatment of metastatic brain tumors.
    Clin Cancer Res. 2006;12:5770-6.
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83. HORMIGO A , Gu B, Karimi S, Riedel E, et al
    YKL-40 and Matrix Metalloproteinase-9 as Potential Serum Biomarkers for Patients with High-Grade Gliomas.
    Clin Cancer Res. 2006;12:5698-5704.
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    September 2006
84. KIM SK , Kim SU, Park IH, Bang JH, et al
    Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression.
    Clin Cancer Res. 2006;12:5550-6.
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85. FOMCHENKO EI , Holland EC
    Mouse models of brain tumors and their applications in preclinical trials.
    Clin Cancer Res. 2006;12:5288-97.
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86. TEICHER BA
    Protein kinase C as a therapeutic target.
    Clin Cancer Res. 2006;12:5336-45.
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    August 2006
87. WEN PY , Yung WK, Lamborn KR, Dahia PL, et al
    Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08.
    Clin Cancer Res. 2006;12:4899-907.
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88. CHAKRAVARTI A , Erkkinen MG, Nestler U, Stupp R, et al
    Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.
    Clin Cancer Res. 2006;12:4738-46.
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89. NEWCOMB EW , Demaria S, Lukyanov Y, Shao Y, et al
    The Combination of Ionizing Radiation and Peripheral Vaccination Produces Long-term Survival of Mice Bearing Established Invasive GL261 Gliomas.
    Clin Cancer Res. 2006;12:4730-4737.
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90. SHU Q , Antalffy B, Su JM, Adesina A, et al
    Valproic Acid Prolongs Survival Time of Severe Combined Immunodeficient Mice Bearing Intracerebellar Orthotopic Medulloblastoma Xenografts.
    Clin Cancer Res. 2006;12:4687-4694.
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91. FRUEHAUF JP , Brem H, Brem S, Sloan A, et al
    In vitro Drug Response and Molecular Markers Associated with Drug Resistance in Malignant Gliomas.
    Clin Cancer Res. 2006;12:4523-32.
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    July 2006
92. FECCI PE , Sweeney AE, Grossi PM, Nair SK, et al
    Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells.
    Clin Cancer Res. 2006;12.
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