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Neoplasms of the CNS

Free Subscription Articles published in Clin Cancer Res Retrieve available abstracts of 78 articles: HTML format Text format

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April 2012
1. DE LAY M , Jahangiri A, Carbonell WS, Hu YL, et al
   Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to anti-angiogenic therapy.
   Clin Cancer Res. 2012.
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2. XIAO Y , Decker PA, Rice T, McCoy LS, et al
   SSBP2 variants are associated with survival in glioblastoma patients.
   Clin Cancer Res. 2012.
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   March 2012
3. GOROVETS D , Kannan K, Shen R, Kastenhuber E, et al
   IDH Mutation and Neuroglial Developmental Features Define Clinically Distinct Subclasses of Lower-Grade Diffuse Astrocytic Glioma.
   Clin Cancer Res. 2012.
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4. BROWN CE , Starr R, Aguilar B, Shami A, et al
   Stem-like tumor initiating cells isolated from IL13Ralpha2-expressing gliomas are targeted and killed by IL13-zetakine redirected T cells.
   Clin Cancer Res. 2012.
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   February 2012
5. ADVANI SJ , Buckel L, Chen NG, Scanderbeg DJ, et al
   Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts.
   Clin Cancer Res. 2012.
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6. SCHULTE A , Gunther HS, Martens T, Zapf S, et al
   Glioblastoma stem-like cell lines with either maintenance or loss of high-level EGFR amplification, generated via modulation of ligand concentration.
   Clin Cancer Res. 2012.
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   January 2012
7. MIYAZAKI T , Pan Y, Joshi K, Purohit D, et al
   Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.
   Clin Cancer Res. 2012.
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   November 2011
8. LEMKE D , Pfenning PN, Sahm F, Klein AK, et al
   Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness.
   Clin Cancer Res. 2011.
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9. TSIEN CI , Brown D, Normolle D, Schipper M, et al
   Concurrent Temozolomide and Dose-Escalated Intensity Modulated Radiation Therapy in Newly Diagnosed Glioblastoma.
   Clin Cancer Res. 2011.
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10. KOUL D , Shen R, Fu J, Lafortune TA, et al
    Antitumor activity of NVP-BKM120- a selective pan class 1 PI3 Kinase inhibitor showed differential forms of cell death based on P53 status of glioma cells.
    Clin Cancer Res. 2011.
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    October 2011
11. CHEEMA TA , Kanai R, Kim GW, Wakimoto H, et al
    Enhanced anti-tumor efficacy of low dose etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts.
    Clin Cancer Res. 2011.
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    September 2011
12. SIPPEL TR , White JT, Nag K, Tsvankin V, et al
    Neutrophil Degranulation and Immunosuppression in Patients with Glioblastoma: Restoration of Cellular Immune Function by Targeting Arginase I.
    Clin Cancer Res. 2011.
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13. PRILLER M , Poschl J, Abrao L, von Bueren AO, et al
    Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients.
    Clin Cancer Res. 2011.
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14. VAN DEN BENT MJ , Gravendeel LA, Gorlia T, Kros JM, et al
    A hypermethylated phenotype in anaplastic oligodendroglial brain tumors is a better predictor of survival than MGMT methylation in anaplastic oligodendroglioma: a report from EORTC study 26951.
    Clin Cancer Res. 2011.
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    August 2011
15. WARDAK M , Schiepers C, Dahlbom M, Cloughesy TF, et al
    Discriminant Analysis of 18F-Fluoro-Thymidine Kinetic Parameters to Predict Survival in Patients with Recurrent High-Grade Glioma.
    Clin Cancer Res. 2011.
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16. DE GROOT JF
    High-Dose Antiangiogenic Therapy for Glioblastoma: Less May Be More?
    Clin Cancer Res. 2011.
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    July 2011
17. VON BAUMGARTEN LD , Brucker D, Tirniceru AL, Kienast Y, et al
    Bevacizumab has differential and dose-dependent effects on glioma blood vessels and tumor cells.
    Clin Cancer Res. 2011.
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18. BRUFSKY AM , Mayer M, Rugo HS, Kaufman PA, et al
    Central Nervous System Metastases in Patients with HER2-Positive Metastatic Breast Cancer: Incidence, Treatment, and Survival in Patients from registHER.
    Clin Cancer Res. 2011;17:4834-4843.
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19. WHITE-KONING M , Civade E, Geoerger B, Thomas F, et al
    Population analysis of erlotinib in adults and children reveals pharmacokinetic characteristics as the main factor explaining tolerance particularities in children.
    Clin Cancer Res. 2011;17:4862-71.
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20. JACOB K , Quang-Khuong DA, Jones DT, Witt H, et al
    Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas.
    Clin Cancer Res. 2011;17:4650-60.
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21. GROSSMAN SA , Ye X, Lesser G, Sloan AE, et al
    Immunosuppression in Patients with High Grade Gliomas Treated with Radiation and Temozolomide.
    Clin Cancer Res. 2011.
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22. BRAGGIO E , McPhail ER, Macon W, Lopes MB, et al
    Primary central nervous system lymphomas: a validation study of array-based comparative genomic hybridization in formalin-fixed paraffin-embedded tumor specimens.
    Clin Cancer Res. 2011;17:4245-53.
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23. KLEIJN A , Chen JW, Buhrman JS, Wojtkiewicz GR, et al
    Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging.
    Clin Cancer Res. 2011;17:4484-93.
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    June 2011
24. KIPRIANOVA I , Thomas N, Ayache A, Fischer M, et al
    Regression of glioma in rat models by intranasal application of parvovirus H-1.
    Clin Cancer Res. 2011.
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25. MINEHARU Y , King GD, Muhammad AG, Bannykh S, et al
    Engineering the brain tumor microenvironment enhances the efficacy of dendritic cells' vaccination: implications for clinical trials design.
    Clin Cancer Res. 2011.
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26. SAMPSON JH , Mitchell DA
    Is Cytomegalovirus a Therapeutic Target in Glioblastoma?
    Clin Cancer Res. 2011.
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27. DE GROOT JF , Piao Y, Tran HT, Gilbert MR, et al
    Myeloid Biomarkers Associated with Glioblastoma Response to Anti-Vascular Endothelial Growth Factor Therapy with Aflibercept.
    Clin Cancer Res. 2011.
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28. RAABE EH , Lim KS, Kim JM, Meeker A, et al
    BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.
    Clin Cancer Res. 2011;17:3590-9.
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29. KOOS B , Bender S, Witt H, Mertsch S, et al
    The transcription factor evi-1 is overexpressed, promotes proliferation, and is prognostically unfavorable in infratentorial ependymomas.
    Clin Cancer Res. 2011;17:3631-7.
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    May 2011
30. OPEL D , Naumann I, Schneider M, Bertele D, et al
    Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma.
    Clin Cancer Res. 2011;17:3233-47.
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31. HOLSKEN A , Gebhardt M, Buchfelder M, Fahlbusch R, et al
    EGFR signaling regulates tumor cell migration in craniopharyngiomas.
    Clin Cancer Res. 2011.
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32. HARTMANN C , Hentschel B, Tatagiba M, Schramm J, et al
    Molecular markers in low-grade gliomas: predictive or prognostic?
    Clin Cancer Res. 2011.
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    April 2011
33. VREDENBURGH JJ , Desjardins A, Reardon DA, Peters KB, et al
    The Addition of Bevacizumab to Standard Radiation Therapy and Temozolomide Followed by Bevacizumab, Temozolomide and Irinotecan for Newly Diagnosed Glioblastoma.
    Clin Cancer Res. 2011.
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34. GALBAN CJ , Chenevert TL, Meyer CR, Tsien CI, et al
    Prospective analysis of parametric MRI biomarkers: Identification of early and distinct glioma response patterns not predicted by standard radiographic assessment.
    Clin Cancer Res. 2011.
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35. GOUNDER M , Spriggs DR
    Inclusion of Brain Metastases in Phase I trials: A No-Brainer?
    Clin Cancer Res. 2011.
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36. UNTERKIRCHER T , Cristofanon S, Vellanki SH, Nonnenmacher L, et al
    Bortezomib primes glioblastoma including glioblastoma stem cells for TRAIL by increasing tBid stability and mitochondrial apoptosis.
    Clin Cancer Res. 2011.
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37. KANAI R , Wakimoto H, Martuza RL, Rabkin SD, et al
    A Novel Oncolytic Herpes Simplex Virus that Synergizes with Phosphatidylinositol 3-Kinase/Akt Pathway Inhibitors to Target Glioblastoma Stem Cells.
    Clin Cancer Res. 2011.
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38. MULDOON LL , Lewin SJ, Dosa E, Kraemer DF, et al
    Imaging and therapy with rituximab anti-CD20 immunotherapy in an animal model of central nervous system lymphoma.
    Clin Cancer Res. 2011;17:2207-15.
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39. DZIURZYNSKI K , Wei J, Qiao W, Hatiboglu MA, et al
    Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype.
    Clin Cancer Res. 2011.
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40. LOHR J , Ratliff T, Huppertz A, Ge Y, et al
    Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived transforming growth factor-betas.
    Clin Cancer Res. 2011.
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    March 2011
41. TSIMBERIDOU AM , Letourneau K, Wen S, Wheler JJ, et al
    Phase I Clinical Trials in 93 Patients with Brain Metastases: The M. D. Anderson Cancer Center Experience.
    Clin Cancer Res. 2011.
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42. DMITRIEVA N , Yu L, Viapiano M, Cripe TP, et al
    Chondroitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy.
    Clin Cancer Res. 2011;17:1362-72.
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43. MOROZ MA , Huang R, Kochetkov T, Shi W, et al
    Comparison of Corticotropin-Releasing Factor, Dexamethasone and Temozolomide: Treatment Efficacy and Toxicity in U87 and C6 Intracranial Gliomas.
    Clin Cancer Res. 2011.
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    February 2011
44. SCHWALBE EC , Lindsey JC, Straughton D, Hogg TL, et al
    Rapid diagnosis of medulloblastoma molecular subgroups.
    Clin Cancer Res. 2011.
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45. KHAN AJ , Wall BA, Ahlawat S, Green C, et al
    Riluzole Enhances Ionizing Radiation-induced Cytotoxicity in Human Melanoma Cells that Ectopically Express Metabotropic Glutamate Receptor 1 In Vitro and In Vivo.
    Clin Cancer Res. 2011.
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46. SU JM , Li XN, Thompson P, Ou CN, et al
    Phase 1 study of valproic acid in pediatric patients with refractory solid or CNS tumors: a children's oncology group report.
    Clin Cancer Res. 2011;17:589-97.
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    January 2011
47. ABLA O , Weitzman S, Blay JY, O'Neill BP, et al
    Primary CNS lymphoma in children and adolescents: a descriptive analysis from the International Primary CNS Lymphoma Collaborative Group (IPCG).
    Clin Cancer Res. 2011;17:346-52.
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48. TIE J , Lipton L, Desai J, Gibbs P, et al
    KRAS Mutation is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer.
    Clin Cancer Res. 2011.
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49. DE TAYRAC M , Aubry M, Saikali S, Etcheverry A, et al
    A 4-Gene Signature Associated with Clinical Outcome in High-Grade Gliomas.
    Clin Cancer Res. 2011.
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50. CLOUGHESY TF , Mischel PS
    New strategies in the molecular targeting of glioblastoma: how do you hit a moving target?
    Clin Cancer Res. 2011;17:6-11.
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    December 2010
51. SCHRECK KC , Taylor P, Marchionni L, Gopalakrishnan V, et al
    The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
    Clin Cancer Res. 2010;16:6060-70.
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52. PRINS RM , Soto H, Konkankit V, Odesa SK, et al
    Gene expression profile correlates with T cell infiltration and survival in glioblastoma patients vaccinated with dendritic cell immunotherapy.
    Clin Cancer Res. 2010.
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53. WEISSENBERGER J , Priester M, Bernreuther C, Rakel S, et al
    Dietary Curcumin Attenuates Glioma Growth in a Syngeneic Mouse Model by Inhibition of the JAK1,2/STAT3 Signaling Pathway.
    Clin Cancer Res. 2010;16:5781-95.
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    November 2010
54. SCIUSCIO D , Diserens AC, van Dommelen K, Martinet D, et al
    Extent and Patterns of MGMT Promoter Methylation in Glioblastoma and Respective Derived Spheres.
    Clin Cancer Res. 2010.
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55. ZHAO D , Alizadeh D, Zhang L, Liu W, et al
    Carbon Nanotubes Enhance CpG Uptake and Potentiate Anti-Glioma Immunity.
    Clin Cancer Res. 2010.
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56. GRIL B , Palmieri D, Qian Y, Smart D, et al
    Pazopanib reveals a role for tumor cell B-Raf in the prevention of HER2+ breast cancer brain metastasis.
    Clin Cancer Res. 2010.
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57. SLEDGE GW
    Heading in a New Direction: Drug Permeability in Breast Cancer Brain Metastasis.
    Clin Cancer Res. 2010.
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    October 2010
58. JAMAL M , Rath BH, Williams ES, Camphausen K, et al
    Microenvironmental regulation of glioblastoma radioresponse.
    Clin Cancer Res. 2010.
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59. HEON S , Yeap BY, Britt GJ, Costa DB, et al
    Development of Central Nervous System Metastases in Patients with Advanced Non-Small Cell Lung Cancer and Somatic EGFR Mutations Treated with Gefitinib or Erlotinib.
    Clin Cancer Res. 2010.
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60. KONG LY , Wu A, Doucette T, Wei J, et al
    Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immune therapeutic response.
    Clin Cancer Res. 2010.
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    September 2010
61. SIMON M , Hosking FJ, Marie Y, Gousias K, et al
    Genetic risk profiles identify different molecular etiologies for glioma.
    Clin Cancer Res. 2010.
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62. LOCKMAN PR , Mittapalli RK, Taskar KS, Rudraraju V, et al
    Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Mouse Brain Metastases of Breast Cancer.
    Clin Cancer Res. 2010.
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    August 2010
63. HONG JJ , Rosenberg SA, Dudley ME, Yang JC, et al
    Successful Treatment of Melanoma Brain Metastases With Adoptive Cell Therapy.
    Clin Cancer Res. 2010.
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64. GOUTAGNY S , Yang HW, Zucman-Rossi J, Chan J, et al
    Genomic Profiling Reveals Alternative Genetic Pathways of Meningioma Malignant Progression Dependent on the Underlying NF2 Status.
    Clin Cancer Res. 2010.
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    July 2010
65. GUAN Y , Mizoguchi M, Yoshimoto K, Hata N, et al
    MiRNA-196 Is Up-Regulated in Glioblastoma but not in Anaplastic Astrocytoma and has Prognostic Significance.
    Clin Cancer Res. 2010.
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    June 2010
66. BAX DA , Mackay A, Little SE, Carvalho D, et al
    A Distinct Spectrum of Copy Number Aberrations in Pediatric High-Grade Gliomas.
    Clin Cancer Res. 2010.
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67. ALIZADEH D , Zhang L, Brown CE, Farrukh O, et al
    Induction of Anti-Glioma Natural Killer Cell Response following Multiple Low-Dose Intracerebral CpG Therapy.
    Clin Cancer Res. 2010.
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68. ROTH P , Junker M, Tritschler I, Mittelbronn M, et al
    GDF-15 Contributes to Proliferation and Immune Escape of Malignant Gliomas.
    Clin Cancer Res. 2010.
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    May 2010
69. CHAE SS , Kamoun WS, Farrar CT, Kirkpatrick ND, et al
    Angiopoietin-2 Interferes with Anti-VEGFR-2- Induced Vessel Normalization and Survival Benefit in Mice Bearing Gliomas.
    Clin Cancer Res. 2010.
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70. GRUNDA JM , Fiveash J, Palmer CA, Cantor A, et al
    Rationally designed pharmacogenomic treatment using concurrent capecitabine and radiotherapy for glioblastoma; gene expression profiles associated with outcome.
    Clin Cancer Res. 2010;16:2890-8.
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71. FUJITA M , Scheurer ME, Decker SA, McDonald HA, et al
    Role of Type-1 Interferons in Anti-Glioma Immunosurveillance - Using Mouse Studies to Guide Examination of Novel Prognostic Markers in Humans.
    Clin Cancer Res. 2010.
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72. DE VRIES NA , Bruggeman SW, Hulsman D, de Vries HI, et al
    Rapid and Robust Transgenic High-Grade Glioma Mouse Models for Therapy-Intervention Studies.
    Clin Cancer Res. 2010.
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73. CAMPOS B , Wan F, Farhadi M, Ernst A, et al
    Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells.
    Clin Cancer Res. 2010.
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    April 2010
74. MILDE T , Oehme I, Korshunov A, Kopp-Schneider A, et al
    Histone Deacetylases 5 and 9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth.
    Clin Cancer Res. 2010.
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75. KONG LY , Gelbard A, Wei J, Reina-Ortiz C, et al
    Inhibition of p-STAT3 Enhances IFN-{alpha} Efficacy against Metastatic Melanoma in a Murine Model.
    Clin Cancer Res. 2010.
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76. GROSSMAN SA , Ye X, Piantadosi S, Desideri S, et al
    Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States.
    Clin Cancer Res. 2010.
    PubMed     Text format     Related articles    Abstract available
    
    
    
    March 2010
77. GALBAN CJ , Bhojani MS, Lee KC, Meyer CR, et al
    Evaluation of treatment-associated inflammatory response on diffusion-weighted magnetic resonance imaging and 2-[18F]-fluoro-2-deoxy-D-glucose-positron emission tomography imaging biomarkers.
    Clin Cancer Res. 2010;16:1542-52.
    PubMed     Text format     Related articles    Abstract available
    
    
    
    January 2010
78. BESSE B , Lasserre SF, Compton P, Huang J, et al
    Bevacizumab safety in patients with central nervous system metastases.
    Clin Cancer Res. 2010;16:269-78.
    PubMed     Text format     Related articles    Abstract available
    
    
    

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