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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Liver Cirrhosis

Free Subscription Articles published in J Hepatol Retrieve available abstracts of 151 articles: HTML format

Single Articles

May 2008
1. MATEI V , Rodriguez-Vilarrupla A, Deulofeu R, Garcia-Caldero H, et al
   Three-day tetrahydrobiopterin therapy increases in vivo hepatic NOS activity and reduces portal pressure in CCl(4) cirrhotic rats.
   J Hepatol. 2008;.
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2. FUJITA T
   Is bacterial DNA a surrogate marker of bacterial translocation in cirrhosis?
   J Hepatol. 2008;.
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3. FRANCES R , Such J
   Bacterial DNA translocation in patients with cirrhosis: Reply.
   J Hepatol. 2008;.
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   April 2008
4. REBOUISSOU S , Couchy G, Libbrecht L, Balabaud C, et al
   The beta-catenin pathway is activated in focal nodular hyperplasia but not in cirrhotic FNH-like nodules.
   J Hepatol. 2008;.
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5. O'BEIRNE J , Burroughs AK
   Incidence of adrenal dysfunction in cirrhosis.
   J Hepatol. 2008;.
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   March 2008
6. ASSY N , Pruzansky Y, Gaitini D, Shen Orr Z, et al
   Growth hormone-stimulated IGF-1 generation in cirrhosis reflects hepatocellular dysfunction.
   J Hepatol. 2008;.
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7. STADLBAUER V , Mookerjee RP, Hodges S, Wright GA, et al
   Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis.
   J Hepatol. 2008;.
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8. YANG YY , Lee KC, Huang YT, Wang YW, et al
   Effects of N-acetylcysteine administration in hepatic microcirculation of rats with biliary cirrhosis.
   J Hepatol. 2008;.
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   February 2008
9. BOSCH J , Berzigotti A, Garcia-Pagan JC, Abraldes JG, et al
   The management of portal hypertension: Rational basis, available treatments and future options.
   J Hepatol. 2008;.
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10. ANGELI P , Merkel C
    Pathogenesis and management of hepatorenal syndrome in patients with cirrhosis.
    J Hepatol. 2008;.
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    January 2008
11. CARACENI P , Dazzani F, Salizzoni E, Domenicali M, et al
    Muscle circulation contributes to hyperdynamic circulatory syndrome in advanced cirrhosis.
    J Hepatol. 2008;.
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12. POPOV Y , Patsenker E, Stickel F, Zaks J, et al
    Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies.
    J Hepatol. 2008;.
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13. GOETZ M , Vieth M, Kanzler S, Galle PR, et al
    In vivo confocal laser laparoscopy allows real time subsurface microscopy in animal models of liver disease.
    J Hepatol. 2008;48:91-7.
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    December 2007
14. VALENTI L , Dongiovanni P, Fargion S, Fracanzani AL, et al
    Iron genes, dysmetabolism and fibrosis in chronic hepatitis C.
    J Hepatol. 2007;.
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15. ZAMBRUNI A , Trevisani F, Di Micoli A, Savelli F, et al
    Effect of chronic beta-blockade on QT interval in patients with liver cirrhosis.
    J Hepatol. 2007;.
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16. GIOVANNA F , Bortolotti F, Francesco D
    Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors.
    J Hepatol. 2007;.
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17. VIDALI M , Tripodi MF, Ivaldi A, Zampino R, et al
    Interplay between oxidative stress and hepatic steatosis in the progression of chronic hepatitis C.
    J Hepatol. 2007;.
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18. OGISO T , Nagaki M, Takai S, Tsukada Y, et al
    Granulocyte colony-stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-1beta.
    J Hepatol. 2007;47:816-25.
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    November 2007
19. WASMUTH HE , Zaldivar MM, Berres ML, Werth A, et al
    The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection.
    J Hepatol. 2007;.
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20. LAFFI G , Tarquini R, Marra F
    Thrombocytopenia in chronic liver disease: lessons from transplanted patients.
    J Hepatol. 2007;47:625-9.
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21. STADLBAUER V , Davies NA, Wright G, Jalan R, et al
    Endotoxin measures in patients' sample: how valid are the results?
    J Hepatol. 2007;47:726-7.
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22. MOLLER HJ , Gronbaek H, Schiodt FV, Holland-Fischer P, et al
    Soluble CD163 from activated macrophages predicts mortality in acute liver failure.
    J Hepatol. 2007;47:671-6.
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    October 2007
23. TOYODA H , Kumada T, Kaneoka Y, Murakami Y, et al
    Impact of hepatitis B virus (HBV) X gene integration in liver tissue on hepatocellular carcinoma development in serologically HBV-negative chronic hepatitis C patients.
    J Hepatol. 2007;.
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24. GONZALEZ-NAVAJAS JM , Bellot P, Frances R, Zapater P, et al
    Presence of bacterial-DNA in cirrhosis identifies a subgroup of patients with marked inflammatory response not related to endotoxin.
    J Hepatol. 2007;.
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25. GOODMAN ZD
    Grading and staging systems for inflammation and fibrosis in chronic liver diseases.
    J Hepatol. 2007;47:598-607.
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26. KAMADA Y , Matsumoto H, Tamura S, Fukushima J, et al
    Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model.
    J Hepatol. 2007;47:556-64.
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27. POUSTCHI H , Negro F, Hui J, Cua IH, et al
    Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3.
    J Hepatol. 2007;.
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    September 2007
28. MIURA K , Yoshino R, Hirai Y, Goto T, et al
    Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB.
    J Hepatol. 2007;.
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29. VIVARELLI M , Burra P, Barba GL, Canova D, et al
    Influence of steroids on HCV recurrence after liver transplantation: A prospective study.
    J Hepatol. 2007;.
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30. LAI M , Hyatt BJ, Nasser I, Curry M, et al
    The clinical significance of persistently normal ALT in chronic hepatitis B infection.
    J Hepatol. 2007;.
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31. KNIGHT B , Lim R, Yeoh GC, Olynyk JK, et al
    Interferon-gamma exacerbates liver damage, the hepatic progenitor cell response and fibrosis in a mouse model of chronic liver injury.
    J Hepatol. 2007;.
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32. XUAN A , Bookman I, Cox DW, Heathcote J, et al
    Three atypical cases of Wilson disease: assessment of the Leipzig scoring system in making a diagnosis.
    J Hepatol. 2007;47:428-33.
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    August 2007
33. SUN HC , Zhang W, Qin LX, Zhang BH, et al
    Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma.
    J Hepatol. 2007;.
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34. IMERYUZ N , Tahan V, Sonsuz A, Eren F, et al
    Iron preloading aggravates nutritional steatohepatitis in rats by increasing apoptotic cell death.
    J Hepatol. 2007;.
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35. STEIB CJ , Gerbes AL, Bystron M, Op den Winkel M, et al
    Kupffer cell activation in normal and fibrotic livers increases portal pressure via thromboxane A(2).
    J Hepatol. 2007;47:228-38.
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    July 2007
36. THOMAS HC
    Best practice in the treatment of chronic hepatitis B: A summary of the European Viral Hepatitis Educational Initiative.
    J Hepatol. 2007;.
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37. MELUM E , Friman S, Bjoro K, Rasmussen A, et al
    Hepatitis C impairs survival following liver transplantation irrespective of concomitant hepatocellular carcinoma.
    J Hepatol. 2007;.
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38. ANSELMI K , Stolz DB, Nalesnik M, Watkins SC, et al
    Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition.
    J Hepatol. 2007;47:103-13.
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39. SHARMA P , Sharma BC, Puri V, Sarin SK, et al
    Critical flicker frequency: diagnostic tool for minimal hepatic encephalopathy.
    J Hepatol. 2007;47:67-73.
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    June 2007
40. DI MARCO V , Almasio PL, Ferraro D, Calvaruso V, et al
    Peg-interferon alone or combined with ribavirin in HCV cirrhosis with portal hypertension: A randomized controlled trial.
    J Hepatol. 2007;.
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41. GRESSNER OA , Lahme B, Demirci I, Gressner AM, et al
    Differential effects of TGF-beta on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes.
    J Hepatol. 2007;.
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42. CASTANO G
    Angiogenesis II type 1 receptor blockade in early cirrhosis.
    J Hepatol. 2007;.
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43. RIGAMONTI C , Fraquelli M
    Do not trivialize the Fibroscan examination, value its accuracy.
    J Hepatol. 2007;46:1149.
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44. BORKHAM-KAMPHORST E , van Roeyen CR, Ostendorf T, Floege J, et al
    Pro-fibrogenic potential of PDGF-D in liver fibrosis.
    J Hepatol. 2007;46:1064-74.
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    May 2007
45. KISHNANI PS , Chen YT
    Important role of abnormal glycogen structure in the development of liver cirrhosis and progression to hepatocellular carcinoma in patients with glycogen storage disease type-III.
    J Hepatol. 2007;.
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46. HERREMA H , Smit GP, Reijngoud DJ, Kuipers F, et al
    Does increased fatty acid oxidation enhance development of liver cirrhosis and progression to hepatocellular carcinoma in patients with glycogen storage disease type-III?
    J Hepatol. 2007;.
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47. ARROYO V , Terra C, Gines P
    Advances in the pathogenesis and treatment of type-1 and type-2 hepatorenal syndrome.
    J Hepatol. 2007;46:935-46.
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48. HEMMANN S , Graf J, Roderfeld M, Roeb E, et al
    Expression of MMPs and TIMPs in liver fibrosis - a systematic review with special emphasis on anti-fibrotic strategies.
    J Hepatol. 2007;46:955-75.
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49. BURROUGHS AK , Cholongitas E
    Non-invasive tests for liver fibrosis: encouraging or discouraging results?
    J Hepatol. 2007;46:751-5.
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50. BYKOV I , Jauhiainen M, Olkkonen VM, Saarikoski ST, et al
    Hepatic gene expression and lipid parameters in complement C3(-/-) mice that do not develop ethanol-induced steatosis.
    J Hepatol. 2007;46:907-14.
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    April 2007
51. RYDER SD
    Outcome of hepatitis C infection: Bleak or benign?
    J Hepatol. 2007;.
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52. SCHOTT E , Witt H, Neumann K, Taube S, et al
    A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection.
    J Hepatol. 2007;.
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53. HUI CK , Zhang HY, Lee NP, Chan W, et al
    Serum adiponectin is increased in advancing liver fibrosis and declines with reduction in fibrosis in chronic hepatitis B.
    J Hepatol. 2007;.
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54. WARD SM , Fox BC, Brown PJ, Worthington J, et al
    Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection.
    J Hepatol. 2007;.
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55. HANSEN S , Moller S, Bendtsen F, Jensen G, et al
    Diurnal variation and dispersion in QT interval in cirrhosis: Relation to haemodynamic changes.
    J Hepatol. 2007;.
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56. GRACIA-SANCHO J , Lavina B, Rodriguez-Vilarrupla A, Garcia-Caldero H, et al
    Enhanced vasoconstrictor prostanoid production by sinusoidal endothelial cells increases portal perfusion pressure in cirrhotic rat livers.
    J Hepatol. 2007;.
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57. HONDA Y , Yamagiwa S, Matsuda Y, Takamura M, et al
    Altered expression of TLR homolog RP105 on monocytes hypersensitive to LPS in patients with primary biliary cirrhosis.
    J Hepatol. 2007;.
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58. HERATH CB , Warner FJ, Lubel JS, Dean RG, et al
    Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis>
    J Hepatol. 2007;.
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59. AFDHAL NH , Curry M
    Technology evaluation: a critical step in the clinical utilization of novel diagnostic tests for liver fibrosis.
    J Hepatol. 2007;46:543-5.
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60. GLUUD C , Brok J, Gong Y, Koretz RL, et al
    Hepatology may have problems with putative surrogate outcome measures.
    J Hepatol. 2007;46:734-42.
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    March 2007
61. GINES P
    The Vaptans: A promising therapy in the management of advanced cirrhosis.
    J Hepatol. 2007;.
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62. HOLLAND-FISCHER P , Andersen PH, Lund S, Pedersen SB, et al
    Muscle GLUT4 in cirrhosis.
    J Hepatol. 2007;.
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63. LAWSON A , Hagan S, Rye K, Taguri N, et al
    The natural history of hepatitis C with severe hepatic fibrosis.
    J Hepatol. 2007;.
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64. IWAKIRI Y , Groszmann RJ
    Vascular endothelial dysfunction in cirrhosis.
    J Hepatol. 2007;.
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65. GIEWEKEMEYER K , Berding G, Ahl B, Ennen JC, et al
    Bradykinesia in cirrhotic patients with early hepatic encephalopathy is related to a decreased glucose uptake of frontomesial cortical areas relevant for movement initiation.
    J Hepatol. 2007;.
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66. VAN OS E , van den Broek WW, Mulder PG, Ter Borg PC, et al
    Depression in patients with primary biliary cirrhosis and primary sclerosing cholangitis.
    J Hepatol. 2007;.
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    February 2007
67. TAZI KA , Bieche I, Paradis V, Guichard C, et al
    In vivo altered unfolded protein response and apoptosis in livers from lipopolysaccharide-challenged cirrhotic rats.
    J Hepatol. 2007;.
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68. BOSETTI C , Levi F, Lucchini F, Zatonski WA, et al
    Worldwide mortality from cirrhosis: An update to 2002.
    J Hepatol. 2007;.
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69. ABRALDES JG , Rodriguez-Vilarrupla A, Graupera M, Zafra C, et al
    Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl(4) cirrhotic rats.
    J Hepatol. 2007;.
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70. DEBERNARDI-VENON W , Martini S, Biasi F, Vizio B, et al
    AT1 receptor antagonist Candesartan in selected cirrhotic patients: Effect on portal pressure and liver fibrosis markers.
    J Hepatol. 2007;.
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71. LIN CY , Tsai IF, Ho YP, Huang CT, et al
    Endotoxemia contributes to the immune paralysis in patients with liver cirrhosis.
    J Hepatol. 2007;.
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72. MILLER AM , Masrorpour M, Klaus C, Zhang JX, et al
    LPS exacerbates endothelin-1 induced activation of cytosolic phospholipase A2 and thromboxane A2 production from Kupffer cells of the prefibrotic rat liver.
    J Hepatol. 2007;46:276-85.
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73. WENG H , Mertens PR, Gressner AM, Dooley S, et al
    IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads.
    J Hepatol. 2007;46:295-303.
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    January 2007
74. RODRIGUEZ-TORRES M , Rodriguez-Orengo JF, Rios-Bedoya CF, Fernandez-Carbia A, et al
    Effect of hepatitis C virus (HCV) treatment in fibrosis progression rate (FPR) and time to cirrhosis (TTC) in patients co-infected with human immunodeficiency virus (HIV): A paired liver biopsy study.
    J Hepatol. 2007;.
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75. LEROY V , Hilleret MN, Sturm N, Trocme C, et al
    Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
    J Hepatol. 2007;.
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76. ESMAT G , Metwally M, Zalata KR, Gadalla S, et al
    Evaluation of serum biomarkers of fibrosis and injury in Egyptian patients with chronic hepatitis C.
    J Hepatol. 2007;.
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77. KUO A , Terrault NA
    Antiviral therapy in liver transplant recipients: Is SVR the only endpoint that matters?
    J Hepatol. 2007;.
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78. MARRA F
    Leptin and liver tissue repair: do rodent models provide the answers?
    J Hepatol. 2007;46:12-8.
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79. KNIGHT B , Akhurst B, Matthews VB, Ruddell RG, et al
    Attenuated liver progenitor (oval) cell and fibrogenic responses to the choline deficient, ethionine supplemented diet in the BALB/c inbred strain of mice.
    J Hepatol. 2007;46:134-41.
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80. GUYOT C , Combe C, Balabaud C, Bioulac-Sage P, et al
    Fibrogenic cell fate during fibrotic tissue remodelling observed in rat and human cultured liver slices.
    J Hepatol. 2007;46:142-50.
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    December 2006
81. FRANCES R , Chiva M, Sanchez E, Gonzalez-Navajas JM, et al
    Bacterial translocation is downregulated by anti-TNF-alpha monoclonal antibody administration in rats with cirrhosis and ascites.
    J Hepatol. 2006;.
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82. CASTERA L , Denis J, Babany G, Roudot-Thoraval F, et al
    Evolving practices of non-invasive markers of liver fibrosis in patients with chronic hepatitis C in France: Time for new guidelines?
    J Hepatol. 2006;.
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83. GEERTS AM , Cheung KJ, Vlierberghe HV, De Vriese AS, et al
    Decreased leukocyte recruitment in the mesenteric microcirculation of rats with cirrhosis is partially restored by treatment with peginterferon: An in vivo study.
    J Hepatol. 2006;.
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84. KETTANEH A , Marcellin P, Douvin C, Poupon R, et al
    Features associated with success rate and performance of fibroscan measurements for the diagnosis of cirrhosis in HCV patients: A prospective study of 935 patients.
    J Hepatol. 2006;.
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    November 2006
85. NAVASA M , Forns X
    Antiviral therapy in HCV decompensated cirrhosis: To treat or not to treat?
    J Hepatol. 2006;.
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86. MONTAGNESE S , Jackson C, Morgan MY
    Spatio-temporal decomposition of the electroencephalogram in patients with cirrhosis.
    J Hepatol. 2006;.
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87. BONKOVSKY HL , Snow KK, Malet PF, Back-Madruga C, et al
    Health-related quality of life in patients with chronic hepatitis C and advanced fibrosis.
    J Hepatol. 2006;.
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88. KREMER-TAL S , Narla G, Chen Y, Hod E, et al
    Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
    J Hepatol. 2006;.
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89. PEREIRA RM , Dos Santos RA, Teixeira MM, Leite VH, et al
    The renin-angiotensin system in a rat model of hepatic fibrosis: Evidence for a protective role of Angiotensin-(1-7).
    J Hepatol. 2006;.
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90. FERNANDEZ-VARO G , Morales-Ruiz M, Ros J, Tugues S, et al
    Impaired extracellular matrix degradation in aortic vessels of cirrhotic rats.
    J Hepatol. 2006;.
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91. KALAMBOKIS G , Fotopoulos A, Economou M, Pappas K, et al
    Effects of a 7-day treatment with midodrine in non-azotemic cirrhotic patients without and with ascites.
    J Hepatol. 2006;.
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92. GUYADER D , Thirouard AS, Erdtmann L, Rakba N, et al
    Liver iron is a surrogate marker of severe fibrosis in chronic hepatitis C.
    J Hepatol. 2006;.
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93. DEMO E , Frush D, Gottfried M, Koepke J, et al
    Glycogen storage disease type III-hepatocellular carcinoma a long-term complication?
    J Hepatol. 2006;.
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94. LAU GK
    Does treatment with interferon-based therapy improve the natural history of chronic hepatitis B infection?
    J Hepatol. 2006;.
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95. HALFON P , Bacq Y, De Muret A, Penaranda G, et al
    Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C.
    J Hepatol. 2006;.
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96. KUMAR ACHARYA S , Kumar Sharma P, Singh R, Kumar Mohanty S, et al
    Hepatitis E virus (HEV) infection in patients with cirrhosis is associated with rapid decompensation and death.
    J Hepatol. 2006;.
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97. TAVAKOLI S , Hajrasouliha AR, Jabehdar-Maralani P, Ebrahimi F, et al
    Reduced susceptibility to epinephrine-induced arrhythmias in cirrhotic rats: The roles of nitric oxide and endogenous opioid peptides.
    J Hepatol. 2006;.
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98. SCHOTT E , Witt H, Hinrichsen H, Neumann K, et al
    Gender-dependent association of CTLA4 polymorphisms with resolution of hepatitis C virus infection.
    J Hepatol. 2006;.
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99. MIGITA K , Maeda Y, Abiru S, Nakamura M, et al
    Polymorphisms of interleukin-1beta in Japanese patients with hepatitis B virus infection.
    J Hepatol. 2006;.
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100. PARK YN , Roncalli M
     Large liver cell dysplasia: a controversial entity.
     J Hepatol. 2006;45:734-43.
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101. VAN DE BOVENKAMP M , Groothuis GM, Meijer DK, Olinga P, et al
     Precision-cut fibrotic rat liver slices as a new model to test the effects of anti-fibrotic drugs in vitro.
     J Hepatol. 2006;45:696-703.
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     October 2006
102. ABE W , Ikejima K, Lang T, Okumura K, et al
     Low molecular weight heparin prevents hepatic fibrogenesis caused by carbon tetrachloride in the rat.
     J Hepatol. 2006;.
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103. LIN SM , Yu ML, Lee CM, Chien RN, et al
     Interferon therapy in HBeAg positive chronic hepatitis reduces cirrhosis and hepatocellular carcinoma.
     J Hepatol. 2006;.
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104. IACOBELLIS A , Siciliano M, Perri F, Annicchiarico BE, et al
     Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis: A controlled study.
     J Hepatol. 2006;.
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105. DE LEDINGHEN V , Ratziu V, Causse X, Le Bail B, et al
     Diagnostic and predictive factors of significant liver fibrosis and minimal lesions in patients with persistent unexplained elevated transaminases. A prospective multicenter study.
     J Hepatol. 2006;45:592-9.
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     September 2006
106. JESSEN N , Buhl ES, Schmitz O, Lund S, et al
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