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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Hepatitis C

Free Subscription Articles published in J Hepatol Retrieve available abstracts of 151 articles: HTML format

Single Articles

May 2008
1. BURIONI R , Perotti M, Mancini N, Clementi M, et al
   Perspectives for the utilization of neutralizing human monoclonal antibodies as anti-HCV drugs.
   J Hepatol. 2008;.
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2. OVERBECK K , Genne D, Golay A, Negro F, et al
   Pioglitazone in chronic hepatitis C not responding to pegylated interferon-alpha and ribavirin.
   J Hepatol. 2008;.
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3. ZEUZEM S
   Telaprevir, peginterferon alfa-2a, and ribavirin for 28 days in chronic hepatitis C patients.
   J Hepatol. 2008;.
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4. BERENGUER M
   Systematic review of the treatment of established recurrent hepatitis C with pegylated interferon in combination with ribavirin.
   J Hepatol. 2008;.
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5. DEUFFIC-BURBAN S , Deltenre P, Louvet A, Canva V, et al
   Impact of viral eradication on mortality related to hepatitis C: A modeling approach in France.
   J Hepatol. 2008;.
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6. SU X , Yee LJ, Im K, Rhodes SL, et al
   Association of single nucleotide polymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the response to interferon therapy for chronic hepatitis C.
   J Hepatol. 2008;.
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7. LIBRA M , Gloghini A, Malaponte G, Gangemi P, et al
   In gastrointestinal mucosa-associated lymphoid tissue lymphomas t(14;18)-(IgH/Bcl-2) translocation clusters in hepatitis C virus-infected patients.
   J Hepatol. 2008;.
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8. SHORES NJ , Maida I, Soriano V, Nunez M, et al
   Sexual transmission is associated with spontaneous HCV clearance in HIV-infected patients.
   J Hepatol. 2008;.
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   April 2008
9. BERNSMEIER C , Duong FH, Christen V, Pugnale P, et al
   Virus induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C.
   J Hepatol. 2008;.
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10. POTTHOFF A , Wedemeyer H, Boecher WO, Berg T, et al
    The HEP-NET B/C co-infection trial: A prospective multicenter study to investigate the efficacy of pegylated interferon-alpha2b and ribavirin in patients with HBV/HCV co-infection.
    J Hepatol. 2008;.
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11. LAWITZ E , Rodriguez-Torres M, Muir AJ, Kieffer TL, et al
    Antiviral effects and safety of telaprevir, peginterferon alfa-2a, and ribavirin for 28 days in hepatitis C patients.
    J Hepatol. 2008;.
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12. ANDRE P , Lotteau V
    Hepatitis C virus assembly: When fat makes it easier.
    J Hepatol. 2008;.
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13. FORTON DM , Hamilton G, Allsop JM, Grover VP, et al
    Cerebral immune activation in chronic hepatitis C infection: A magnetic resonance spectroscopy study.
    J Hepatol. 2008;.
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14. DAI CY , Chuang WL, Ho CK, Hsieh MY, et al
    Associations between hepatitis C viremia and low serum triglyceride and cholesterol levels: A community-based study.
    J Hepatol. 2008;.
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15. BARTH H , Robinet E, Liang TJ, Baumert TF, et al
    Mouse models for the study of HCV infection and virus-host interactions.
    J Hepatol. 2008;.
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16. PEFFAULT DE LATOUR R , Ribaud P, Robin M, Valla D, et al
    Allogeneic hematopoietic cell transplant in HCV-infected patients.
    J Hepatol. 2008;.
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    March 2008
17. FORNS X , Sanchez-Tapias JM, Bruguera M
    Nosocomial acquisition of the hepatitis C virus.
    J Hepatol. 2008;.
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18. PUGNALE P , Herrmann E, Neumann AU, Pawlotsky JM, et al
    Hepatitis C viral kinetics in plasma and peripheral blood mononuclear cells during pegylated interferon-alpha2a/ribavirin therapy.
    J Hepatol. 2008;.
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19. DETERDING K , Wiegand J, Gruner N, Wedemeyer H, et al
    Medical procedures as a risk factor for HCV infection in developed countries: Do we neglect a significant problem in medical care?
    J Hepatol. 2008;.
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20. KAPLAN DE , Ikeda F, Li Y, Nakamoto N, et al
    Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis.
    J Hepatol. 2008;.
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21. BROERING R , Wu J, Meng Z, Hilgard P, et al
    Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication.
    J Hepatol. 2008;.
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    February 2008
22. SELZNER N , Chen L, Borozan I, Edwards A, et al
    Hepatic gene expression and prediction of therapy response in chronic hepatitis C patients.
    J Hepatol. 2008;.
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23. KUROSAKI M , Matsunaga K, Hirayama I, Tanaka T, et al
    The presence of steatosis and elevation of alanine aminotransferase levels are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy.
    J Hepatol. 2008;.
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24. CACOUB P , Carrat F, Bedossa P, Lambert J, et al
    Comparison of non-invasive liver fibrosis biomarkers in HIV/HCV co-infected patients: The fibrovic study - ANRS HC02.
    J Hepatol. 2008;.
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25. LEROY V , Zarski JP
    Clinical applicability of non-invasive markers for liver fibrosis in chronic hepatitis C.
    J Hepatol. 2008;.
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26. RODRIGUEZ-TORRES M , Govindarajan S, Sola R, Clumeck N, et al
    Hepatic steatosis in HCV/HIV co-infected patients: Correlates, efficacy and outcomes of anti-HCV therapy: A paired liver biopsy study.
    J Hepatol. 2008;.
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    January 2008
27. URBANI S , Amadei B, Tola D, Pedrazzi G, et al
    Restoration of HCV-specific T cell functions by PD-1/PD-L1 blockade in HCV infection: Effect of viremia levels and antiviral treatment.
    J Hepatol. 2008;.
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28. MALLAT A , Hezode C, Lotersztajn S
    Environmental factors as disease accelerators during chronic hepatitis C.
    J Hepatol. 2008;.
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29. ROMERO-GOMEZ M , Fernandez-Rodriguez CM, Andrade RJ, Diago M, et al
    Effect of sustained virological response to treatment on the incidence of abnormal glucose values in chronic hepatitis C.
    J Hepatol. 2008;.
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30. POPOV Y , Patsenker E, Stickel F, Zaks J, et al
    Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies.
    J Hepatol. 2008;.
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    December 2007
31. VALENTI L , Dongiovanni P, Fargion S, Fracanzani AL, et al
    Iron genes, dysmetabolism and fibrosis in chronic hepatitis C.
    J Hepatol. 2007;.
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32. LUPBERGER J , Brino L, Baumert TF
    RNAi - A powerful tool to unravel hepatitis C virus-host interactions within the infectious life cycle.
    J Hepatol. 2007;.
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33. EL-SERAG H , Kramer JR
    Hepatitis C infection: Dying with or from the infection?
    J Hepatol. 2007;.
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34. SULKOWSKI MS
    Viral hepatitis and HIV coinfection.
    J Hepatol. 2007;.
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35. VIDALI M , Tripodi MF, Ivaldi A, Zampino R, et al
    Interplay between oxidative stress and hepatic steatosis in the progression of chronic hepatitis C.
    J Hepatol. 2007;.
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36. SCHOLTES C , Diaz O, Icard V, Kaul A, et al
    Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR.
    J Hepatol. 2007;.
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    November 2007
37. WASMUTH HE , Zaldivar MM, Berres ML, Werth A, et al
    The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection.
    J Hepatol. 2007;.
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38. MARCELLIN P , Pequignot F, Delarocque-Astagneau E, Zarski JP, et al
    Mortality related to chronic hepatitis B and chronic hepatitis C in France: Evidence for the role of HIV coinfection and alcohol consumption.
    J Hepatol. 2007;.
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39. SCOTTA C , Garbuglia AR, Ruggeri L, Spada E, et al
    Influence of specific CD4+ T cells and antibodies on evolution of hypervariable region 1 during acute HCV infection.
    J Hepatol. 2007;.
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40. SZABO G , Dolganiuc A
    Hepatitis C core protein - The "core" of immune deception?
    J Hepatol. 2007;.
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41. SULKOWSKI M
    Treatment of hepatitis C in HIV-infected persons: A work in progress.
    J Hepatol. 2007;.
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42. ALTER MJ
    Healthcare should not be a vehicle for transmission of hepatitis C virus.
    J Hepatol. 2007;.
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43. ESTEBAN JI , Sauleda S, Quer J
    The changing epidemiology of hepatitis C virus infection in Europe.
    J Hepatol. 2007;.
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    October 2007
44. SCHMITZ KJ , Wohlschlaeger J, Lang H, Sotiropoulos GC, et al
    Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection.
    J Hepatol. 2007;.
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45. TOYODA H , Kumada T, Kaneoka Y, Murakami Y, et al
    Impact of hepatitis B virus (HBV) X gene integration in liver tissue on hepatocellular carcinoma development in serologically HBV-negative chronic hepatitis C patients.
    J Hepatol. 2007;.
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46. ZIMMERMANN M , Flechsig C, Monica NL, Tripodi M, et al
    Hepatitis C virus core protein impairs in vitro priming of specific T cell responses by dendritic cells and hepatocytes.
    J Hepatol. 2007;.
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47. MARTI NEZ-BAUER E , Forns X, Armelles M, Planas R, et al
    Hospital admission is a relevant source of hepatitis C virus acquisition in Spain.
    J Hepatol. 2007;.
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48. BROWN RS JR
    Steroids in recurrent hepatitis C following liver transplantation: Pitfall or panacea?
    J Hepatol. 2007;.
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49. CACOUB P , Halfon P, Rosenthal E, Pialoux G, et al
    Treatment of hepatitis C virus in human immunodeficiency virus infected patients in "real life": Modifications in two large surveys between 2004 and 2006.
    J Hepatol. 2007;.
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50. POUSTCHI H , Negro F, Hui J, Cua IH, et al
    Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3.
    J Hepatol. 2007;.
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    September 2007
51. VIVARELLI M , Burra P, Barba GL, Canova D, et al
    Influence of steroids on HCV recurrence after liver transplantation: A prospective study.
    J Hepatol. 2007;.
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52. DAL PERO F , Di Maira G, Marin O, Bortoletto G, et al
    Heterogeneity of CK2 phosphorylation sites in the NS5A protein of different hepatitis C virus genotypes.
    J Hepatol. 2007;.
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    July 2007
53. RAJENDRA A , Wong JB
    Economics of chronic hepatitis B and hepatitis C.
    J Hepatol. 2007;.
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54. MARCELLIN P , Heathcote EJ, Craxi A
    Which patients with genotype 1 chronic hepatitis C can benefit from prolonged treatment with the 'accordion' regimen?
    J Hepatol. 2007;.
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55. JENSEN GS , Trotter JF
    Treatment of chronic HCV in advanced liver disease: Unmet challenges, reason for optimism.
    J Hepatol. 2007;.
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56. WATANABE T , Umehara T, Yasui F, Nakagawa SI, et al
    Liver target delivery of small interfering RNA to the HCV gene by lactosylated cationic liposome.
    J Hepatol. 2007;.
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57. MELUM E , Friman S, Bjoro K, Rasmussen A, et al
    Hepatitis C impairs survival following liver transplantation irrespective of concomitant hepatocellular carcinoma.
    J Hepatol. 2007;.
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58. BRAU N , Fox RK, Xiao P, Marks K, et al
    Presentation and outcome of hepatocellular carcinoma in HIV-infected patients: A U.S.-Canadian multicenter study.
    J Hepatol. 2007;.
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    June 2007
59. DI MARCO V , Almasio PL, Ferraro D, Calvaruso V, et al
    Peg-interferon alone or combined with ribavirin in HCV cirrhosis with portal hypertension: A randomized controlled trial.
    J Hepatol. 2007;.
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60. MARCELLIN P , Horsmans Y, Nevens F, Grange JD, et al
    Phase 2 study of the combination of merimepodib with peginterferon-alpha2b, and ribavirin in nonresponders to previous therapy for chronic hepatitis C.
    J Hepatol. 2007;.
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61. VELDT BJ , van der Vliet HJ, von Blomberg BM, van Vlierberghe H, et al
    Randomized placebo controlled phase I/II trial of alpha-galactosylceramide for the treatment of chronic hepatitis C.
    J Hepatol. 2007;.
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    May 2007
62. SCHULTHEISS M , Thimme R
    Toll like receptor 7 and hepatitis C virus infection.
    J Hepatol. 2007;.
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63. LARRUBIA JR , Calvino M, Benito S, Sanz-de-Villalobos E, et al
    The role of CCR5/CXCR3 expressing CD8+ cells in liver damage and viral control during persistent hepatitis C virus infection.
    J Hepatol. 2007;.
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64. AHLENSTIEL G , Nischalke HD, Bueren K, Berg T, et al
    The GNB3 C825T polymorphism affects response to HCV therapy with pegylated interferon in HCV/HIV co-infected but not in HCV mono-infected patients.
    J Hepatol. 2007;.
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65. POCKROS PJ , Guyader D, Patton H, Tong MJ, et al
    Oral resiquimod in chronic HCV infection: Safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies>
    J Hepatol. 2007;.
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66. BURROUGHS AK , Cholongitas E
    Non-invasive tests for liver fibrosis: encouraging or discouraging results?
    J Hepatol. 2007;46:751-5.
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    April 2007
67. RYDER SD
    Outcome of hepatitis C infection: Bleak or benign?
    J Hepatol. 2007;.
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68. BENHAMOU Y
    Anemia and clinical outcomes in hepatitis C.
    J Hepatol. 2007;.
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69. SOUVIGNET C , Maynard M, Gagnieu MC, Trepo C, et al
    Ribavirin in combination therapy for HCV chronic infection in HIV patients: How to win the war after winning the first battle?
    J Hepatol. 2007;.
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70. WARD SM , Fox BC, Brown PJ, Worthington J, et al
    Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection.
    J Hepatol. 2007;.
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71. LAI WK , Curbishley SM, Goddard S, Alabrabra E, et al
    Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function.
    J Hepatol. 2007;.
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72. SCHOTT E , Witt H, Neumann K, Taube S, et al
    A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection.
    J Hepatol. 2007;.
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73. GLUUD C , Brok J, Gong Y, Koretz RL, et al
    Hepatology may have problems with putative surrogate outcome measures.
    J Hepatol. 2007;46:734-42.
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74. BUENDIA MA
    Tumor suppressors in hepatocellular carcinoma: many are called, but few are chosen.
    J Hepatol. 2007;46:546-8.
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    March 2007
75. CLEMENT S , Negro F
    Hepatitis C virus: The viral way to fatty liver.
    J Hepatol. 2007;.
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76. SAMUEL D , Roche B
    Ribavirin in the treatment of recurrent hepatitis C after liver transplantation: Difficult to manage but essential for success.
    J Hepatol. 2007;.
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77. GISH RG , Arora S, Reddy KR, Nelson DR, et al
    Virological response and safety outcomes in therapy-nai ve patients treated for chronic hepatitis C with taribavirin or ribavirin in combination with pegylated interferon alfa-2a: A randomized, phase 2 study.
    J Hepatol. 2007;.
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78. LAWSON A , Hagan S, Rye K, Taguri N, et al
    The natural history of hepatitis C with severe hepatic fibrosis.
    J Hepatol. 2007;.
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79. FILLEBEEN C , Muckenthaler M, Andriopoulos B, Bisaillon M, et al
    Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells.
    J Hepatol. 2007;.
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    February 2007
80. DAHARI H , Markatou M, Zeremski M, Haller I, et al
    Early ribavirin pharmacokinetics, HCV RNA and alanine aminotransferase kinetics in HIV/HCV co-infected patients during treatment with pegylated interferon and ribavirin.
    J Hepatol. 2007;.
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81. BOSETTI C , Levi F, Lucchini F, Zatonski WA, et al
    Worldwide mortality from cirrhosis: An update to 2002.
    J Hepatol. 2007;.
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82. FERENCI P , Ferenci S, Datz C, Rezman I, et al
    Morbidity and mortality in paid Austrian plasma donors infected with hepatitis C at plasma donation in the 1970s.
    J Hepatol. 2007;.
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83. TARGHER G , Bertolini L, Padovani R, Rodella S, et al
    Differences and similarities in early atherosclerosis between patients with non-alcoholic steatohepatitis and chronic hepatitis B and C.
    J Hepatol. 2007;.
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84. ANGELICO M , Petrolati A, Lionetti R, Lenci I, et al
    A randomized study on Peg-interferon alfa-2a with or without ribavirin in liver transplant recipients with recurrent hepatitis C.
    J Hepatol. 2007;.
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85. RENDINA M , Schena A, Castellaneta NM, Losito F, et al
    The treatment of chronic hepatitis C with peginterferon alfa-2a (40kDa) plus ribavirin in haemodialysed patients awaiting renal transplant.
    J Hepatol. 2007;.
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86. SILVA M
    Reply to issues raised in the Jansen/Reesink editorial.
    J Hepatol. 2007;46:350-1.
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    January 2007
87. RODRIGUEZ-TORRES M , Rodriguez-Orengo JF, Rios-Bedoya CF, Fernandez-Carbia A, et al
    Effect of hepatitis C virus (HCV) treatment in fibrosis progression rate (FPR) and time to cirrhosis (TTC) in patients co-infected with human immunodeficiency virus (HIV): A paired liver biopsy study.
    J Hepatol. 2007;.
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88. LEROY V , Hilleret MN, Sturm N, Trocme C, et al
    Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
    J Hepatol. 2007;.
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89. BORTOLOTTI F , Jorio R, Resti M, Camma C, et al
    Epidemiological profile of 806 Italian children with hepatitis C virus infection over a 15-year period.
    J Hepatol. 2007;.
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90. ESMAT G , Metwally M, Zalata KR, Gadalla S, et al
    Evaluation of serum biomarkers of fibrosis and injury in Egyptian patients with chronic hepatitis C.
    J Hepatol. 2007;.
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91. REHERMANN B , Naoumov NV
    Immunological techniques in viral hepatitis.
    J Hepatol. 2007;.
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92. KUO A , Terrault NA
    Antiviral therapy in liver transplant recipients: Is SVR the only endpoint that matters?
    J Hepatol. 2007;.
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    December 2006
93. VON HAHN T , McKeating JA
    In vitro veritas? The challenges of studying hepatitis C virus infectivity in a test tube.
    J Hepatol. 2006;.
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94. CASTERA L , Denis J, Babany G, Roudot-Thoraval F, et al
    Evolving practices of non-invasive markers of liver fibrosis in patients with chronic hepatitis C in France: Time for new guidelines?
    J Hepatol. 2006;.
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95. LAN KH , Lan KL, Lee WP, Sheu ML, et al
    HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell lines.
    J Hepatol. 2006;.
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96. KETTANEH A , Marcellin P, Douvin C, Poupon R, et al
    Features associated with success rate and performance of fibroscan measurements for the diagnosis of cirrhosis in HCV patients: A prospective study of 935 patients.
    J Hepatol. 2006;.
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97. VIDALI M , Occhino G, Ivaldi A, Serino R, et al
    Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C.
    J Hepatol. 2006;.
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    November 2006
98. SIERRA F
    Peginterferon alfa-2b vs. peginterferon alfa-2a in the treatment of hepatitis C, is there any difference?
    J Hepatol. 2006;.
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99. NAVASA M , Forns X
    Antiviral therapy in HCV decompensated cirrhosis: To treat or not to treat?
    J Hepatol. 2006;.
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100. JACKEL-CRAM C , Babiuk LA, Liu Q
     Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: Genotype-3a core has a stronger effect than genotype-1b core.
     J Hepatol. 2006;.
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101. EL-KAREF A , Kaito M, Tanaka H, Ikeda K, et al
     Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C.
     J Hepatol. 2006;.
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102. PICCIOTTO FP , Tritto G, Lanza AG, Addario L, et al
     Sustained virological response to antiviral therapy reduces mortality in HCV reinfection after liver transplantation.
     J Hepatol. 2006;.
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103. BONKOVSKY HL , Snow KK, Malet PF, Back-Madruga C, et al
     Health-related quality of life in patients with chronic hepatitis C and advanced fibrosis.
     J Hepatol. 2006;.
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104. MOUCARI R , Ripault MP, Oules V, Martinot-Peignoux M, et al
     High predictive value of early viral kinetics in retreatment with peginterferon and ribavirin of chronic hepatitis C patients non-responders to standard combination therapy.
     J Hepatol. 2006;.
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105. KREMER-TAL S , Narla G, Chen Y, Hod E, et al
     Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
     J Hepatol. 2006;.
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106. MOLINA S , Castet V, Fournier-Wirth C, Pichard-Garcia L, et al
     The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus.
     J Hepatol. 2006;.
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107. DEMELIA L , Civolani A, Murgia D, Murru A, et al
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