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Bone Marrow Transplantation

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November 2011
1. MARCONDES AM , Li X, Tabellini L, Bartenstein M, et al
   Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
   Blood. 2011;118:5031-9.
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   October 2011
2. JAAKO P , Flygare J, Olsson K, Quere R, et al
   Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
   Blood. 2011.
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   September 2011
3. ROBB RJ , Kreijveld E, Kuns RD, Wilson YA, et al
   Type I-IFNs control GVHD and GVL responses after transplantation.
   Blood. 2011;118:3399-409.
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4. SOKOLIC R , Maric I, Kesserwan C, Garabedian E, et al
   Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency.
   Blood. 2011;118:2688-94.
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5. SHI J , Fallahi M, Luo JL, Petrie HT, et al
   Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.
   Blood. 2011;118:2511-9.
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6. CUDEJKO C , Wouters K, Fuentes L, Hannou SA, et al
   p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
   Blood. 2011;118:2556-66.
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7. HUBERT FX , Kinkel SA, Davey GM, Phipson B, et al
   Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.
   Blood. 2011;118:2462-72.
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   August 2011
8. AUE G , Du Y, Cleveland SM, Smith SB, et al
   Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia.
   Blood. 2011.
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9. KOHRT HE , Muller AM, Baker J, Goldstein MJ, et al
   Donor immunization with WT1 peptide augments anti-leukemic activity after MHC-matched bone marrow transplantation.
   Blood. 2011.
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10. OTSURU S , Rasini V, Bussolari R, Hofmann TJ, et al
    Cytokine-induced osteopoietic differentiation of transplanted marrow cells.
    Blood. 2011;118:2358-61.
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11. BUZA-VIDAS N , Woll P, Hultquist A, Duarte S, et al
    FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
    Blood. 2011;118:1544-8.
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12. SUN CL , Francisco L, Baker KS, Weisdorf DJ, et al
    Adverse psychological outcomes in long-term survivors of hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study.
    Blood. 2011.
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    July 2011
13. LAI L , Cui C, Jin J, Hao Z, et al
    Mouse embryonic stem cell-derived thymic epithelial cell progenitors enhance T-cell reconstitution after allogeneic bone marrow transplantation.
    Blood. 2011.
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14. YAGASAKI H , Kojima S, Yabe H, Kato K, et al
    Acceptable HLA-mismatching in unrelated donor bone marrow transplantation for patients with acquired severe aplastic anemia.
    Blood. 2011.
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15. WANG J , Liu Y, Li Z, Wang Z, et al
    Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.
    Blood. 2011;118:368-79.
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16. BRUNSTEIN CG , Fuchs EJ, Carter SL, Karanes C, et al
    Alternative donor transplantation after reduced intensity conditioning: results of parallel phase 2 trials using partially HLA-mismatched related bone marrow or unrelated double umbilical cord blood grafts.
    Blood. 2011;118:282-8.
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17. NISHIMOTO N , Arai S, Ichikawa M, Nakagawa M, et al
    Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through downregulation of p19ARF.
    Blood. 2011.
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18. SHIN HJ , Baker J, Leveson-Gower DB, Smith AT, et al
    Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells.
    Blood. 2011.
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    June 2011
19. STARON M , Wu S, Hong F, Stojanovic A, et al
    Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex.
    Blood. 2011;117:7136-44.
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20. ROSSI L , Ergen AV, Goodell MA
    TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs.
    Blood. 2011;117:6479-88.
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21. EAPEN M , Le Rademacher J, Antin JH, Champlin RE, et al
    Effect of stem cell source on outcomes after adult unrelated donor transplantation in severe aplastic anemia.
    Blood. 2011.
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22. NG AP , Loughran SJ, Metcalf D, Hyland CD, et al
    Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice.
    Blood. 2011.
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23. ZLOTOFF DA , Zhang SL, De Obaldia ME, Hess PR, et al
    Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation.
    Blood. 2011.
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24. ARMENIAN SH , Sun CL, Kawashima T, Arora M, et al
    Long-term health-related outcomes in survivors of childhood cancer treated with hematopoietic cell transplantation (HCT) versus conventional therapy: a report from the Bone Marrow Transplant Survivor Study (BMTSS) and Childhood Cancer Survivor Study (
    Blood. 2011.
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25. SANDERS JE , Woolfrey AE, Carpenter PA, Storer BE, et al
    Late effects among pediatric patients followed for nearly four decades after transplantation for severe aplastic anemia.
    Blood. 2011.
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26. SCHANIEL C , Sirabella D, Qiu J, Niu X, et al
    Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells.
    Blood. 2011.
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27. KING KY , Baldridge MT, Weksberg DC, Chambers SM, et al
    Irgm1 protects hematopoietic stem cells by negative regulation of interferon signaling.
    Blood. 2011.
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    May 2011
28. YAO D , Huang Y, Huang X, Wang W, et al
    Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions.
    Blood. 2011;117:5652-62.
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29. ZHU HH , Ji K, Alderson N, He Z, et al
    Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool.
    Blood. 2011;117:5350-61.
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30. LUCAS CL , Workman CJ, Beyaz S, LoCascio S, et al
    LAG-3, TGF-beta, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L.
    Blood. 2011;117:5532-40.
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31. BOLES NC , Lin KK, Lukov GL, Bowman TV, et al
    CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation.
    Blood. 2011.
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    April 2011
32. WESTERHUIS G , van Pel M, Toes RE, Staal FJ, et al
    Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells.
    Blood. 2011;117:4400-1.
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33. GOPAL AK , Guthrie KA, Rajendran J, Pagel JM, et al
    90Y-ibritumomab tiuxetan, fludarabine, and TBI based non-myeloablative allogeneic transplant conditioning for patients with persistent high-risk B-cell lymphoma.
    Blood. 2011.
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34. ZHANG L , Jiang Q, Li G, Jeffrey J, et al
    Efficient infection and impairment of pDC in the bone marrow and peripheral lymphoid organs during early HIV-1 infection in humanized rag2-/-{gamma}C-/- mice in vivo.
    Blood. 2011.
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35. GAVINS FN , Russell J, Senchenkova EL, De Almeida Paula L, et al
    Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S.
    Blood. 2011;117:4125-33.
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36. QUERE R , Karlsson G, Hertwig F, Rissler M, et al
    SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
    Blood. 2011.
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    March 2011
37. NGUYEN NY , Maxwell MJ, Ooms LM, Davies EM, et al
    An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.
    Blood. 2011.
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    February 2011
38. VAN ROOSBROECK K , Cox L, Tousseyn T, Lahortiga I, et al
    JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma.
    Blood. 2011.
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    January 2011
39. ULYANOVA T , Jiang Y, Padilla S, Nakamoto B, et al
    Combinatorial and distinct roles of alpha and alpha integrins in stress erythropoiesis in mice.
    Blood. 2011;117:975-85.
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40. DUTT S , Baker J, Kohrt HE, Kambham N, et al
    CD8+ CD44hi but not CD4+ CD44hi memory T cells mediate potent graft anti-lymphoma activity without GVHD.
    Blood. 2011.
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41. ASTWOOD E , Vora A
    Erythroblastic islands.
    Blood. 2011;117:10.
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42. SAKATA-YANAGIMOTO M , Sakai T, Miyake Y, Saito TI, et al
    Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine.
    Blood. 2011;117:128-34.
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43. KATO N , Kitaura J, Doki N, Komeno Y, et al
    Two types of C/EBPalpha mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models.
    Blood. 2011;117:221-33.
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    December 2010
44. BEILKE JN , Benjamin J, Lanier LL
    The requirement for NKG2D in NK cell-mediated rejection of parental bone marrow grafts is determined by MHC class I expressed by the graft recipient.
    Blood. 2010;116:5208-16.
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45. LYMPERI S , Ersek A, Ferraro F, Dazzi F, et al
    Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo.
    Blood. 2010.
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    November 2010
46. SABLOFF M , Chandy M, Wang Z, Logan BR, et al
    HLA-matched sibling bone marrow transplantation for {beta}-thalassemia major.
    Blood. 2010.
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47. GIROUX M , Delisle JS, Gauthier SD, Heinonen KM, et al
    SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage.
    Blood. 2010.
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48. ZHAO F , Zhang Y, Wang H, Jin M, et al
    Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease.
    Blood. 2010.
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    October 2010
49. MANSOOR A , Pittaluga S, Beck PL, Wilson WH, et al
    NK-cell enteropathy: a benign NK-cell lymphoproliferative disease mimicking intestinal lymphoma: clinicopathological features and follow-up in a unique case series.
    Blood. 2010.
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50. TAKAKU T , Malide D, Chen J, Calado RT, et al
    Hematopoiesis in 3 dimensions: human and murine bone marrow architecture visualized by confocal microscopy.
    Blood. 2010;116:e41-55.
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51. WANG J , Liu Y, Li Z, Du J, et al
    Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia.
    Blood. 2010.
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    September 2010
52. JANDA A , Sedlacek P, Honig M, Friedrich W, et al
    Multicenter survey on the outcome of transplantation of hematopoietic cells in patients with the complete form of DiGeorge anomaly.
    Blood. 2010;116:2229-36.
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53. ZHANG Y , Sandy AR, Wang J, Radojcic V, et al
    Notch signaling is a critical regulator of allogeneic CD4+ T cell responses mediating graft-versus-host disease.
    Blood. 2010.
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54. FRIEDBICHLER K , Kerenyi MA, Kovacic B, Li G, et al
    Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.
    Blood. 2010;116:1548-58.
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55. DEV A , Fang J, Sathyanarayana P, Pradeep A, et al
    During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast pool.
    Blood. 2010.
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    August 2010
56. HIGHFILL SL , Rodriguez PC, Zhou Q, Goetz CA, et al
    Bone marrow myeloid-derived suppressor cells (MDSC) inhibit graft-versus-host (GVHD) disease via an arginase-1 dependent mechanism that is upregulated by IL-13.
    Blood. 2010.
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57. ZHANG G , Shi Q, Fahs SA, Kuether EL, et al
    Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice.
    Blood. 2010;116:1235-43.
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58. MAJEWSKI IJ , Ritchie ME, Phipson B, Corbin J, et al
    Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.
    Blood. 2010;116:731-9.
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    July 2010
59. SHAW PJ , Kan F, Ahn KW, Spellman SR, et al
    Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related or matched unrelated donors.
    Blood. 2010.
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60. SUN CL , Francisco L, Kawashima T, Leisenring W, et al
    Prevalence and predictors of chronic health conditions after hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study.
    Blood. 2010.
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61. XU D , Wang S, Yu WM, Chan G, et al
    A gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.
    Blood. 2010.
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    May 2010
62. OLSON JA , Leveson-Gower DB, Gill S, Baker J, et al
    NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects.
    Blood. 2010;115:4293-301.
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63. OHKI M , Ohki Y, Ishihara M, Nishida C, et al
    Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration.
    Blood. 2010;115:4302-12.
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64. ARGIROPOULOS B , Yung E, Xiang P, Lo CY, et al
    Linkage of the potent leukemogenic activity of Meis1 to cell-cycle entry and transcriptional regulation of cyclin D3.
    Blood. 2010;115:4071-82.
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65. LI J , Spensberger D, Ahn JS, Anand S, et al
    JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia.
    Blood. 2010.
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66. ZHOU S , Mody D, Deravin SS, Hauer J, et al
    A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells.
    Blood. 2010.
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67. GUIHARD S , Clay D, Cocault L, Saulnier N, et al
    The MAPK ERK1 is a negative regulator of the adult steady-state splenic erythropoiesis.
    Blood. 2010;115:3686-94.
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68. VOGTENHUBER C , Bucher C, Highfill SL, Koch LK, et al
    Constitutively active Stat5b in CD4+ T-cells inhibits graft-versus-host disease (GVHD) lethality associated with increased regulatory T-cell (Treg) potency and decreased T effector cell (Teff) responses.
    Blood. 2010.
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    April 2010
69. HILL GR , Olver SD, Kuns RD, Varelias A, et al
    Stem cell mobilization with G-CSF induces Type-17 differentiation and promotes scleroderma.
    Blood. 2010.
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70. DEDHIA PH , Keeshan K, Uljon S, Xu L, et al
    Differential ability of Tribbles family members to promote degradation of C/EBP{alpha} and induce acute myelogenous leukemia.
    Blood. 2010.
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71. GRIMWADE D , Hills RK, Moorman AV, Walker H, et al
    Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities amongst 5,876 younger adult patients treated in the UK Medical Research Council trials.
    Blood. 2010.
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72. YABE H , Yabe M, Koike T, Shimizu T, et al
    Rapid improvement of life-threatening capillary leak syndrome after stem cell transplantation by bevacizumab.
    Blood. 2010;115:2723-4.
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    March 2010
73. DAVIS JE , Ritchie DS
    B cells in GVHD: friend or foe?
    Blood. 2010;115:2558-9.
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74. STARON M , Yang Y, Liu B, Li J, et al
    gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis.
    Blood. 2010;115:2380-90.
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75. KERNS HM , Ryu BY, Stirling BV, Sather BD, et al
    B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.
    Blood. 2010;115:2146-55.
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76. LOGES S , Schmidt T, Tjwa M, van Geyte K, et al
    Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.
    Blood. 2010;115:2264-73.
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77. OPHIR E , Eidelstein Y, Afik R, Bachar-Lustig E, et al
    Induction of tolerance to bone marrow allografts by donor-derived host nonreactive ex vivo-induced central memory CD8 T cells.
    Blood. 2010;115:2095-104.
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78. VICENTE R , Adjali O, Jacquet C, Zimmermann VS, et al
    Intrathymic transplantation of bone marrow-derived progenitors provides long-term thymopoiesis.
    Blood. 2010;115:1913-20.
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79. PALUMBO A , Bringhen S, Bruno B, Falcone AP, et al
    Melphalan 200 mg/m(2) versus melphalan 100 mg/m(2) in newly diagnosed myeloma patients: a prospective, multicenter phase 3 study.
    Blood. 2010;115:1873-9.
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80. AGRAWAL-SINGH S , Koschmieder S, Gelsing S, Stocking C, et al
    Pim2 cooperates with PML-RAR{alpha} to induce acute myeloid leukemia in a bone marrow transplantation model.
    Blood. 2010.
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    February 2010
81. MEDYOUF H , Gao X, Armstrong F, Gusscott S, et al
    Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
    Blood. 2010;115:1175-84.
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82. FEHR T , Lucas CL, Kurtz J, Onoe T, et al
    A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo.
    Blood. 2010;115:1280-7.
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83. SODANI P , Isgro A, Gaziev J, Polchi P, et al
    Purified T-depleted, CD34+ peripheral blood and bone marrow cell transplantation from haploidentical mother to child with thalassemia.
    Blood. 2010;115:1296-302.
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84. PECQUET C , Staerk J, Chaligne R, Goss V, et al
    Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor.
    Blood. 2010;115:1037-48.
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85. LUZNIK L , Bolanos-Meade J, Zahurak M, Chen AR, et al
    High-dose cyclophosphamide as single agent, short-course prophylaxis of graft-versus-host disease.
    Blood. 2010.
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    January 2010
86. BJORKLUND AT , Schaffer M, Fauriat C, Ringden O, et al
    NK cells expressing inhibitory KIR for non-self ligands remain tolerant in HLA-matched sibling stem cell transplantation.
    Blood. 2010.
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87. KOLESNICK R , van den Brink M, Heller G, Rotolo JA, et al
    Response: Sample size and statistical comparisons of GVHD rates in pediatric Niemann-Pick disease patients.
    Blood. 2010;115:436.
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88. TOLAR J , Eapen M, Orchard PJ, Blazar BR, et al
    Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease.
    Blood. 2010;115:434-5.
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89. MCDERMOTT DH , Conway SE, Wang T, Ricklefs SM, et al
    Donor and recipient chemokine receptor CCR5 genotype is associated with survival after bone marrow transplantation.
    Blood. 2010.
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90. COOKE KR
    A role for lymphotoxin in GVHD and GVL.
    Blood. 2010;115:3-4.
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91. SANCHEZ-ABARCA LI , Gutierrez-Cosio S, Santamaria C, Caballero-Velazquez T, et al
    Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.
    Blood. 2010;115:107-21.
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92. MARKEY KA , Burman AC, Banovic T, Kuns RD, et al
    Soluble lymphotoxin is an important effector molecule in GVHD and GVL.
    Blood. 2010;115:122-32.
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    December 2009
93. SUN Y , Shao L, Bai H, Wang ZZ, et al
    Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration.
    Blood. 2009.
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94. KHARAS MG , Okabe R, Ganis JJ, Gozo M, et al
    Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice.
    Blood. 2009.
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95. VERDUZCO LA , Nathan DG
    Sickle cell disease and stroke.
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