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	The Medical Article of the Year 2008

Breast Cancer

Free Subscription Articles published in Clin Cancer Res Retrieve available abstracts of 133 articles: HTML format

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June 2008
1. HAYES DF , Smerage J
   Is there a role for circulating tumor cells in the management of breast cancer?
   Clin Cancer Res. 2008;14:3646-50.
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2. STEEG PS
   Heterogeneity of drug target expression among metastatic lesions: lessons from a breast cancer autopsy program.
   Clin Cancer Res. 2008;14:3643-5.
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3. TRAN MA , Smith CD, Kester M, Robertson GP, et al
   Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development.
   Clin Cancer Res. 2008;14:3571-81.
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4. FIEGL H , Jones A, Hauser-Kronberger C, Hutarew G, et al
   Methylated NEUROD1 Promoter is a Marker for Chemosensitivity in Breast Cancer.
   Clin Cancer Res. 2008;14:3494-502.
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5. SAUER G , Schneiderhan-Marra N, Kazmaier C, Hutzel K, et al
   Prediction of Nodal Involvement in Breast Cancer Based on Multiparametric Protein Analyses from Preoperative Core Needle Biopsies of the Primary Lesion.
   Clin Cancer Res. 2008;14:3345-3353.
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6. LI J , Zhang N, Song LB, Liao WT, et al
   Astrocyte Elevated Gene-1 is a Novel Prognostic Marker for Breast Cancer Progression and Overall Patient Survival.
   Clin Cancer Res. 2008;14:3319-3326.
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7. BIDARD FC , Vincent-Salomon A, Gomme S, Nos C, et al
   Disseminated Tumor Cells of Breast Cancer Patients: A Strong Prognostic Factor for Distant and Local Relapse.
   Clin Cancer Res. 2008;14:3306-3311.
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   May 2008
8. HOLMES CE , Huang JC, Pace TR, Howard AB, et al
   Tamoxifen and aromatase inhibitors differentially affect vascular endothelial growth factor and endostatin levels in women with breast cancer.
   Clin Cancer Res. 2008;14:3070-6.
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9. WITTNER BS , Sgroi DC, Ryan PD, Bruinsma TJ, et al
   Analysis of the MammaPrint Breast Cancer Assay in a Predominantly Postmenopausal Cohort.
   Clin Cancer Res. 2008;14:2988-2993.
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10. VAN DEN EYNDEN GG , Smid M, Van Laere SJ, Colpaert CG, et al
    Gene Expression Profiles Associated with the Presence of a Fibrotic Focus and the Growth Pattern in Lymph Node-Negative Breast Cancer.
    Clin Cancer Res. 2008;14:2944-2952.
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11. PORTERA CC , Walshe JM, Rosing DR, Denduluri N, et al
    Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with trastuzumab-insensitive human epidermal growth factor receptor 2-positive metastatic breast cancer.
    Clin Cancer Res. 2008;14:2710-6.
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12. BRENNAN DJ , Rexhepaj E, O'Brien SL, McSherry E, et al
    Altered Cytoplasmic-to-Nuclear Ratio of Survivin Is a Prognostic Indicator in Breast Cancer.
    Clin Cancer Res. 2008;14:2681-9.
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13. GENERALI D , Fox SB, Brizzi MP, Allevi G, et al
    Down-Regulation of Phosphatidylinositol 3'-Kinase/AKT/Molecular Target of Rapamycin Metabolic Pathway by Primary Letrozole-Based Therapy in Human Breast Cancer.
    Clin Cancer Res. 2008;14:2673-80.
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14. BANERJEE S , Pancholi S, A'hern R, Ghazoui Z, et al
    The effects of neoadjuvant anastrozole and tamoxifen on circulating vascular endothelial growth factor and soluble vascular endothelial growth factor receptor 1 in breast cancer.
    Clin Cancer Res. 2008;14:2656-63.
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15. MA XJ , Salunga R, Dahiya S, Wang W, et al
    A Five-Gene Molecular Grade Index and HOXB13:IL17BR Are Complementary Prognostic Factors in Early Stage Breast Cancer.
    Clin Cancer Res. 2008;14:2601-8.
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16. IGNATIADIS M , Kallergi G, Ntoulia M, Perraki M, et al
    Prognostic Value of the Molecular Detection of Circulating Tumor Cells Using a Multimarker Reverse Transcription-PCR Assay for Cytokeratin 19, Mammaglobin A, and HER2 in Early Breast Cancer.
    Clin Cancer Res. 2008;14:2593-600.
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    April 2008
17. SARKAR C , Chakroborty D, Chowdhury UR, Dasgupta PS, et al
    Dopamine Increases the Efficacy of Anticancer Drugs in Breast and Colon Cancer Preclinical Models.
    Clin Cancer Res. 2008;14:2502-2510.
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18. LADOIRE S , Arnould L, Apetoh L, Coudert B, et al
    Pathologic complete response to neoadjuvant chemotherapy of breast carcinoma is associated with the disappearance of tumor-infiltrating foxp3+ regulatory T cells.
    Clin Cancer Res. 2008;14:2413-20.
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19. DHAKAL HP , Naume B, Synnestvedt M, Borgen E, et al
    Vascularization in primary breast carcinomas: its prognostic significance and relationship with tumor cell dissemination.
    Clin Cancer Res. 2008;14:2341-50.
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20. DERENZINI M , Donati G, Mazzini G, Montanaro L, et al
    Loss of Retinoblastoma Tumor Suppressor Protein Makes Human Breast Cancer Cells More Sensitive to Antimetabolite Exposure.
    Clin Cancer Res. 2008;14:2199-2209.
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21. DUBSKY P , Sevelda P, Jakesz R, Hausmaninger H, et al
    Anemia Is a Significant Prognostic Factor in Local Relapse-Free Survival of Premenopausal Primary Breast Cancer Patients Receiving Adjuvant Cyclophosphamide/Methotrexate/5-Fluorouracil Chemotherapy.
    Clin Cancer Res. 2008;14:2082-2087.
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22. FUJITA T , Liu W, Doihara H, Date H, et al
    Dissection of the APCCdh1-Skp2 Cascade in Breast Cancer.
    Clin Cancer Res. 2008;14:1966-1975.
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23. WU JM , Fackler MJ, Halushka MK, Molavi DW, et al
    Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases.
    Clin Cancer Res. 2008;14:1938-46.
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    March 2008
24. RUDAS M , Lehnert M, Huynh A, Jakesz R, et al
    Cyclin D1 Expression in Breast Cancer Patients Receiving Adjuvant Tamoxifen-Based Therapy.
    Clin Cancer Res. 2008;14:1767-1774.
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25. CHANRION M , Negre V, Fontaine H, Salvetat N, et al
    A Gene Expression Signature that Can Predict the Recurrence of Tamoxifen-Treated Primary Breast Cancer.
    Clin Cancer Res. 2008;14:1744-52.
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26. DAWOOD S , Broglio K, Gonzalez-Angulo AM, Kau SW, et al
    Prognostic Value of Body Mass Index in Locally Advanced Breast Cancer.
    Clin Cancer Res. 2008;14:1718-1725.
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27. SAPRA P , Zhao H, Mehlig M, Malaby J, et al
    Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model.
    Clin Cancer Res. 2008;14:1888-96.
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28. CRESCENZI E , Palumbo G, de Boer J, Brady HJ, et al
    Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy.
    Clin Cancer Res. 2008;14:1877-87.
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29. BENNOUNA J , Delord JP, Campone M, Nguyen L, et al
    Vinflunine: a new microtubule inhibitor agent.
    Clin Cancer Res. 2008;14:1625-32.
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30. CHEANG MC , Voduc D, Bajdik C, Leung S, et al
    Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype.
    Clin Cancer Res. 2008;14:1368-76.
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31. CAMPS C , Buffa FM, Colella S, Moore J, et al
    hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer.
    Clin Cancer Res. 2008;14:1340-1348.
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32. BELLETTI B , Vaidya JS, D'Andrea S, Entschladen F, et al
    Targeted Intraoperative Radiotherapy Impairs the Stimulation of Breast Cancer Cell Proliferation and Invasion Caused by Surgical Wounding.
    Clin Cancer Res. 2008;14:1325-1332.
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    February 2008
33. POOLA I , Abraham J, Marshalleck JJ, Yue Q, et al
    Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias.
    Clin Cancer Res. 2008;14:1274-1280.
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34. LU S , Simin K, Khan A, Mercurio AM, et al
    Analysis of Integrin {beta}4 Expression in Human Breast Cancer: Association with Basal-like Tumors and Prognostic Significance.
    Clin Cancer Res. 2008;14:1050-8.
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35. OCANA A , Pandiella A
    Identifying Breast Cancer Druggable Oncogenic Alterations: Lessons Learned and Future Targeted Options.
    Clin Cancer Res. 2008;14:961-970.
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36. RAVEL D , Dubois V, Quinonero J, Meyer-Losic F, et al
    Preclinical toxicity, toxicokinetics, and antitumoral efficacy studies of DTS-201, a tumor-selective peptidic prodrug of doxorubicin.
    Clin Cancer Res. 2008;14:1258-65.
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37. PEOPLES GE , Holmes JP, Hueman MT, Mittendorf EA, et al
    Combined Clinical Trial Results of a HER2/neu (E75) Vaccine for the Prevention of Recurrence in High-Risk Breast Cancer Patients: U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02.
    Clin Cancer Res. 2008;14:797-803.
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38. ROBINSON MK , Shaller C, Garmestani K, Plascjak PS, et al
    Effective treatment of established human breast tumor xenografts in immunodeficient mice with a single dose of the alpha-emitting radioisotope astatine-211 conjugated to anti-HER2/neu diabodies.
    Clin Cancer Res. 2008;14:875-82.
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39. COLOMER R , Monzo M, Tusquets I, Rifa J, et al
    A single-nucleotide polymorphism in the aromatase gene is associated with the efficacy of the aromatase inhibitor letrozole in advanced breast carcinoma.
    Clin Cancer Res. 2008;14:811-6.
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    January 2008
40. RAKHA E , Ellis I, Reis-Filho J
    Are triple-negative and Basal-like breast cancer synonymous?
    Clin Cancer Res. 2008;14:618.
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41. TAN BK , Tan LK, Yu K, Tan PH, et al
    Clinical validation of a customized multiple signature microarray for breast cancer.
    Clin Cancer Res. 2008;14:461-9.
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42. HASSAN S , Baccarelli A, Salvucci O, Basik M, et al
    Plasma stromal cell-derived factor-1: host derived marker predictive of distant metastasis in breast cancer.
    Clin Cancer Res. 2008;14:446-54.
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43. MARAQA L , Cummings M, Peter MB, Shaaban AM, et al
    Carcinoembryonic Antigen Cell Adhesion Molecule 6 Predicts Breast Cancer Recurrence following Adjuvant Tamoxifen.
    Clin Cancer Res. 2008;14:405-11.
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44. ALLRED DC , Wu Y, Mao S, Nagtegaal ID, et al
    Ductal Carcinoma In situ and the Emergence of Diversity during Breast Cancer Evolution.
    Clin Cancer Res. 2008;14:370-8.
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45. LOWERY AJ , Miller N, McNeill RE, Kerin MJ, et al
    MicroRNAs as Prognostic Indicators and Therapeutic Targets: Potential Effect on Breast Cancer Management.
    Clin Cancer Res. 2008;14:360-5.
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46. NEWMAN SP , Foster PA, Stengel C, Day JM, et al
    STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells.
    Clin Cancer Res. 2008;14:597-606.
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47. LI C , Penet MF, Winnard P Jr, Artemov D, et al
    Image-guided enzyme/prodrug cancer therapy.
    Clin Cancer Res. 2008;14:515-22.
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48. POLYAK K
    Is breast tumor progression really linear?
    Clin Cancer Res. 2008;14:339-41.
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49. CASALINI P , Carcangiu ML, Tammi R, Auvinen P, et al
    Two Distinct Local Relapse Subtypes in Invasive Breast Cancer: Effect on their Prognostic Impact.
    Clin Cancer Res. 2008;14:25-31.
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50. BIRD BR , Swain SM
    Cardiac toxicity in breast cancer survivors: review of potential cardiac problems.
    Clin Cancer Res. 2008;14:14-24.
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    December 2007
51. TILANUS-LINTHORST MM , Obdeijn IM, Hop WC, Causer PA, et al
    BRCA1 Mutation and Young Age Predict Fast Breast Cancer Growth in the Dutch, United Kingdom, and Canadian Magnetic Resonance Imaging Screening Trials.
    Clin Cancer Res. 2007;13:7357-62.
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52. MELCHOR L , Honrado E, Huang J, Alvarez S, et al
    Estrogen receptor status could modulate the genomic pattern in familial and sporadic breast cancer.
    Clin Cancer Res. 2007;13:7305-13.
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53. ROKAVEC M , Justenhoven C, Schroth W, Istrate MA, et al
    A Novel Polymorphism in the Promoter Region of ERBB4 Is Associated with Breast and Colorectal Cancer Risk.
    Clin Cancer Res. 2007;13:7506-14.
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54. HEAPHY CM , Baumgartner KB, Bisoffi M, Baumgartner RN, et al
    Telomere DNA content predicts breast cancer free survival interval.
    Clin Cancer Res. 2007;13:7037-43.
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55. BAYLISS J , Hilger A, Vishnu P, Diehl K, et al
    Reversal of the Estrogen Receptor Negative Phenotype in Breast Cancer and Restoration of Antiestrogen Response.
    Clin Cancer Res. 2007;13:7029-7036.
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56. HEINONEN M , Fagerholm R, Aaltonen K, Kilpivaara O, et al
    Prognostic Role of HuR in Hereditary Breast Cancer.
    Clin Cancer Res. 2007;13:6959-6963.
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57. LOPEZ-TARRUELLA S , Schiff R
    The Dynamics of Estrogen Receptor Status in Breast Cancer: Re-shaping the Paradigm.
    Clin Cancer Res. 2007;13:6921-5.
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58. THAM LS , Holford NH, Hor SY, Tan T, et al
    Lack of Association of Single-Nucleotide Polymorphisms in Pregnane X Receptor, Hepatic Nuclear Factor 4{alpha}, and Constitutive Androstane Receptor with Docetaxel Pharmacokinetics.
    Clin Cancer Res. 2007;13:7126-32.
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    November 2007
59. HUGHES S , Agbaje O, Bowen RL, Holliday DL, et al
    Matrix Metalloproteinase Single-Nucleotide Polymorphisms and Haplotypes Predict Breast Cancer Progression.
    Clin Cancer Res. 2007;13:6673-6680.
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60. BEAN GR , Bryson AD, Pilie PG, Goldenberg V, et al
    Morphologically normal-appearing mammary epithelial cells obtained from high-risk women exhibit methylation silencing of INK4a/ARF.
    Clin Cancer Res. 2007;13.
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61. DE VRIES NA , Zhao J, Kroon E, Buckle T, et al
    P-Glycoprotein and Breast Cancer Resistance Protein: Two Dominant Transporters Working Together in Limiting the Brain Penetration of Topotecan.
    Clin Cancer Res. 2007;13:6440-6449.
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62. WANG Z , Dahiya S, Provencher H, Muir B, et al
    The Prognostic Biomarkers HOXB13, IL17BR, and CHDH Are Regulated by Estrogen in Breast Cancer.
    Clin Cancer Res. 2007;13:6327-6334.
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63. ARNOULD L , Arveux P, Couturier J, Gelly-Marty M, et al
    Pathologic complete response to trastuzumab-based neoadjuvant therapy is related to the level of HER-2 amplification.
    Clin Cancer Res. 2007;13:6404-9.
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    October 2007
64. RIEDL CC , Ponhold L, Flory D, Weber M, et al
    Magnetic Resonance Imaging of the Breast Improves Detection of Invasive Cancer, Preinvasive Cancer, and Premalignant Lesions during Surveillance of Women at High Risk for Breast Cancer.
    Clin Cancer Res. 2007;13:6144-52.
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65. PUSZTAI L , Anderson K, Hess KR
    Pharmacogenomic Predictor Discovery in Phase II Clinical Trials for Breast Cancer.
    Clin Cancer Res. 2007;13:6080-6.
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66. ANGELO P , Anita M, Amalia A, Stefania T, et al
    Phosphatidylinositol 3-kinase in breast cancer: where from here?
    Clin Cancer Res. 2007;13:5988-90.
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67. HOWE LR
    Rexinoids and breast cancer prevention.
    Clin Cancer Res. 2007;13:5983-7.
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68. LIBY K , Royce DB, Risingsong R, Williams CR, et al
    A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland.
    Clin Cancer Res. 2007;13:6237-43.
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69. GULER G , Iliopoulos D, Guler N, Himmetoglu C, et al
    Wwox and Ap2gamma expression levels predict tamoxifen response.
    Clin Cancer Res. 2007;13:6115-21.
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70. KUMAR SR , Quinn TP, Deutscher SL
    Evaluation of an 111In-radiolabeled peptide as a targeting and imaging agent for ErbB-2 receptor expressing breast carcinomas.
    Clin Cancer Res. 2007;13:6070-9.
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71. BARBARESCHI M , Buttitta F, Felicioni L, Cotrupi S, et al
    Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas.
    Clin Cancer Res. 2007;13:6064-9.
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72. OVERMOYER B , Fu P, Hoppel C, Radivoyevitch T, et al
    Inflammatory Breast Cancer as a Model Disease to Study Tumor Angiogenesis: Results of a Phase IB Trial of Combination SU5416 and Doxorubicin.
    Clin Cancer Res. 2007;13:5862-8.
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73. BACHMANN HS , Otterbach F, Callies R, Nuckel H, et al
    The AA Genotype of the Regulatory BCL2 Promoter Polymorphism ( 938C>A) Is Associated with a Favorable Outcome in Lymph Node Negative Invasive Breast Cancer Patients.
    Clin Cancer Res. 2007;13:5790-7.
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74. JIANG J , Sarwar N, Peston D, Kulinskaya E, et al
    Phosphorylation of Estrogen Receptor-{alpha} at Ser167 Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer Patients.
    Clin Cancer Res. 2007;13:5769-76.
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75. GUAN Y , Kuo WL, Stilwell JL, Takano H, et al
    Amplification of PVT1 Contributes to the Pathophysiology of Ovarian and Breast Cancer.
    Clin Cancer Res. 2007;13:5745-55.
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76. ELLIS MJ , Crowder R
    "PIKing" the Winner for Phosphatidylinositol 3-Kinase Inhibitors in ErbB2-Positive Breast Cancer: Let's Not "PTENed" It's Easy!
    Clin Cancer Res. 2007;13:5661-2.
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    September 2007
77. PAGANELLI G , Ferrari M, Ravasi L, Cremonesi M, et al
    Intraoperative avidination for radionuclide therapy: a prospective new development to accelerate radiotherapy in breast cancer.
    Clin Cancer Res. 2007;13:5646s-51s.
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78. WORSHAM MJ , Raju U, Lu M, Kapke A, et al
    Multiplicity of Benign Breast Lesions Is a Risk Factor for Progression to Breast Cancer.
    Clin Cancer Res. 2007;13:5474-5479.
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79. VAN DEN EYNDEN GG , Vandenberghe MK, van Dam PJ, Colpaert CG, et al
    Increased Sentinel Lymph Node Lymphangiogenesis is Associated with Nonsentinel Axillary Lymph Node Involvement in Breast Cancer Patients with a Positive Sentinel Node.
    Clin Cancer Res. 2007;13:5391-7.
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80. THOMASSEN M , Tan Q, Eiriksdottir F, Bak M, et al
    Comparison of Gene Sets for Expression Profiling: Prediction of Metastasis from Low-Malignant Breast Cancer.
    Clin Cancer Res. 2007;13:5355-5360.
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81. WATSON MA , Ylagan LR, Trinkaus KM, Gillanders WE, et al
    Isolation and Molecular Profiling of Bone Marrow Micrometastases Identifies TWIST1 as a Marker of Early Tumor Relapse in Breast Cancer Patients.
    Clin Cancer Res. 2007;13:5001-9.
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82. DWYER RM , Potter-Beirne SM, Harrington KA, Lowery AJ, et al
    Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells.
    Clin Cancer Res. 2007;13:5020-7.
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    August 2007
83. ARUN B , Valero V, Logan C, Broglio K, et al
    Comparison of ductal lavage and random periareolar fine needle aspiration as tissue acquisition methods in early breast cancer prevention trials.
    Clin Cancer Res. 2007;13:4943-8.
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84. RITTER CA , Perez-Torres M, Rinehart C, Guix M, et al
    Human Breast Cancer Cells Selected for Resistance to Trastuzumab In vivo Overexpress Epidermal Growth Factor Receptor and ErbB Ligands and Remain Dependent on the ErbB Receptor Network.
    Clin Cancer Res. 2007;13:4909-4919.
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85. TSUJIMOTO M , Nakabayashi K, Yoshidome K, Kaneko T, et al
    One-step Nucleic Acid Amplification for Intraoperative Detection of Lymph Node Metastasis in Breast Cancer Patients.
    Clin Cancer Res. 2007;13:4807-4816.
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86. FISKUS W , Ren Y, Mohapatra A, Bali P, et al
    Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90.
    Clin Cancer Res. 2007;13:4882-90.
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87. KUMAR R
    ErbB-dependent signaling as a determinant of trastuzumab resistance.
    Clin Cancer Res. 2007;13:4657-9.
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88. FABIAN CJ
    Is there a future for ductal lavage?
    Clin Cancer Res. 2007;13:4655-6.
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89. DENT R , Trudeau M, Pritchard KI, Hanna WM, et al
    Triple-negative breast cancer: clinical features and patterns of recurrence.
    Clin Cancer Res. 2007;13:4429-34.
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90. BADVE S , Turbin D, Thorat MA, Morimiya A, et al
    FOXA1 Expression in Breast Cancer Correlation with Luminal Subtype A and Survival.
    Clin Cancer Res. 2007;13:4415-21.
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91. BARTSCH R , Wenzel C, Altorjai G, Pluschnig U, et al
    Her2 and progesterone receptor status are not predictive of response to fulvestrant treatment.
    Clin Cancer Res. 2007;13.
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    July 2007
92. KUBISTA E , Planellas Gomez JV, Dowsett M, Foidart JM, et al
    Effect of Tibolone on Breast Cancer Cell Proliferation in Postmenopausal ER+ Patients: Results from STEM Trial.
    Clin Cancer Res. 2007;13:4185-90.
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93. NAKAGAWA T , Martinez SR, Goto Y, Koyanagi K, et al
    Detection of circulating tumor cells in early-stage breast cancer metastasis to axillary lymph nodes.
    Clin Cancer Res. 2007;13:4105-10.
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94. LAYMAN RM , Thomas DG, Griffith KA, Smerage JB, et al
    Neoadjuvant docetaxel and capecitabine and the use of thymidine phosphorylase as a predictive biomarker in breast cancer.
    Clin Cancer Res. 2007;13:4092-7.
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