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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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06.08.2008

3 Anticancer Res
2 BMC Cancer
8 Br J Cancer
1 Breast Cancer Res
5 Breast Cancer Res Treat
2 Cancer
2 Cancer Epidemiol Biomarkers Prev
1 Cancer Genet Cytogenet
6 Clin Cancer Res
1 Genes Chromosomes Cancer
3 Int J Radiat Oncol Biol Phys
2 J Biol Chem
1 J Clin Oncol
9 J Natl Cancer Inst
1 J Nucl Med
1 Lancet Oncol
2 Oncogene


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Anticancer Res

  1. LEE JH , Li YC, Ip SW, Hsu SC, et al
    The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway.
    Anticancer Res. 2008;28.
    PubMed     Related articles    Abstract available

  2. FOSTER PA , Stengel C, Ali T, Leese MP, et al
    A comparison of two orally bioavailable anti-cancer agents, IRC-110160 and STX140.
    Anticancer Res. 2008;28.
    PubMed     Related articles    Abstract available

  3. NEUBAUER H , Gall C, Vogel U, Hornung R, et al
    Changes in tumour biological markers during primary systemic chemotherapy (PST).
    Anticancer Res. 2008;28.
    PubMed     Related articles    Abstract available


    BMC Cancer

  4. DE SILVA W , Karunanayake EH, Tennekoon KH, Allen M, et al
    Novel sequence variants and a high frequency of recurrent polymorphisms in BRCA1 gene in Sri Lankan breast cancer patients and at risk individuals.
    BMC Cancer. 2008;8:214.
    PubMed     Related articles    Abstract available

  5. MONTEMURRO F , Redana S, Nole F, Donadio M, et al
    Vinorelbine-based salvage therapy in HER2-positive metastatic breast cancer patients progressing during trastuzumab-containing regimens: a retrospective study.
    BMC Cancer. 2008;8:209.
    PubMed     Related articles    Abstract available


    Br J Cancer

  6. LI L , Mu K, Zhou G, Lan L, et al
    Genomic instability and proliferative activity as risk factors for distant metastases in breast cancer.
    Br J Cancer. 2008;99:513-9.
    PubMed     Related articles    Abstract available

  7. PULITI D , Miccinesi G, Collina N, De Lisi V, et al
    Effectiveness of service screening: a case-control study to assess breast cancer mortality reduction.
    Br J Cancer. 2008;99:423-7.
    PubMed     Related articles    Abstract available

  8. KLINKHAMMER-SCHALKE M , Koller M, Ehret C, Steinger B, et al
    Implementing a system of quality-of-life diagnosis and therapy for breast cancer patients: results of an exploratory trial as a prerequisite for a subsequent RCT.
    Br J Cancer. 2008;99:415-22.
    PubMed     Related articles    Abstract available

  9. MCCARTHY PL , Mercer FC, Savicky MW, Carter BA, et al
    Changes in subcellular localisation of MI-ER1alpha, a novel oestrogen receptor-alpha interacting protein, is associated with breast cancer progression.
    Br J Cancer. 2008.
    PubMed     Related articles    Abstract available

  10. DIRECKS WG , Berndsen SC, Proost N, Peters GJ, et al
    [(18)F]FDG and [(18)F]FLT uptake in human breast cancer cells in relation to the effects of chemotherapy: an in vitro study.
    Br J Cancer. 2008.
    PubMed     Related articles    Abstract available

  11. GUTH U , Huang DJ, Schotzau A, Zanetti-Dallenbach R, et al
    Target and reality of adjuvant endocrine therapy in postmenopausal patients with invasive breast cancer.
    Br J Cancer. 2008.
    PubMed     Related articles    Abstract available

  12. LASH TL , Pedersen L, Cronin-Fenton D, Ahern TP, et al
    Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram.
    Br J Cancer. 2008.
    PubMed     Related articles    Abstract available

  13. WARDLEY AM , Hiller L, Howard HC, Dunn JA, et al
    tAnGo: a randomised phase III trial of gemcitabine in paclitaxel-containing, epirubicin/cyclophosphamide-based, adjuvant chemotherapy for early breast cancer: a prospective pulmonary, cardiac and hepatic function evaluation.
    Br J Cancer. 2008.
    PubMed     Related articles    Abstract available


    Breast Cancer Res

  14. WIRAPATI P , Sotiriou C, Kunkel S, Farmer P, et al
    Meta-analysis of gene-expression profiles in breast cancer: toward a unified understanding of breast cancer sub-typing and prognosis signatures.
    Breast Cancer Res. 2008;10:R65.
    PubMed     Related articles    Abstract available


    Breast Cancer Res Treat

  15. BELOVA L , Delgado B, Kocherginsky M, Melhem A, et al
    Glucocorticoid receptor expression in breast cancer associates with older patient age.
    Breast Cancer Res Treat. 2008.
    PubMed     Related articles    Abstract available

  16. PENTHEROUDAKIS G , Kalogeras KT, Wirtz RM, Grimani I, et al
    Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: a quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial.
    Breast Cancer Res Treat. 2008.
    PubMed     Related articles    Abstract available

  17. BAAK JP , Gudlaugsson E, Skaland I, Guo LH, et al
    Proliferation is the strongest prognosticator in node-negative breast cancer: significance, error sources, alternatives and comparison with molecular prognostic markers.
    Breast Cancer Res Treat. 2008.
    PubMed     Related articles    Abstract available

  18. MOOK S , Schmidt MK, Viale G, Pruneri G, et al
    The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1-3 positive lymph nodes in an independent validation study.
    Breast Cancer Res Treat. 2008.
    PubMed     Related articles    Abstract available

  19. BARTSCH R , Mlineritsch B, Gnant M, Niernberger T, et al
    The Austrian fulvestrant registry: results from a prospective observation of fulvestrant in postmenopausal patients with metastatic breast cancer.
    Breast Cancer Res Treat. 2008.
    PubMed     Related articles    Abstract available


    Cancer

  20. CHEN Z , Arendell L, Aickin M, Cauley J, et al
    Hip bone density predicts breast cancer risk independently of Gail score: results From the Women's Health Initiative.
    Cancer. 2008.
    PubMed     Related articles    Abstract available

  21. ALI SM , Carney WP, Esteva FJ, Fornier M, et al
    Serum HER-2/neu and relative resistance to trastuzumab-based therapy in patients with metastatic breast cancer.
    Cancer. 2008.
    PubMed     Related articles    Abstract available


    Cancer Epidemiol Biomarkers Prev

  22. REDING KW , Daling JR, Doody DR, O'Brien CA, et al
    Effect of Prediagnostic Alcohol Consumption on Survival after Breast Cancer in Young Women.
    Cancer Epidemiol Biomarkers Prev. 2008.
    PubMed     Related articles    Abstract available

  23. PHIPPS AI , Malone KE, Porter PL, Daling JR, et al
    Body Size and Risk of Luminal, HER2-Overexpressing, and Triple-Negative Breast Cancer in Postmenopausal Women.
    Cancer Epidemiol Biomarkers Prev. 2008.
    PubMed     Related articles    Abstract available


    Cancer Genet Cytogenet

  24. SUSPITSIN EN , Due EU, Vu P, Hirvonen A, et al
    TP53 mutations in synchronous and metachronous bilateral breast carcinomas.
    Cancer Genet Cytogenet. 2008;184:119-21.
    PubMed     Related articles   


    Clin Cancer Res

  25. FRIEDLOS F , Lehouritis P, Ogilvie L, Hedley D, et al
    Attenuated salmonella targets prodrug activating enzyme carboxypeptidase g2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy.
    Clin Cancer Res. 2008;14:4259-66.
    PubMed     Related articles    Abstract available

  26. CHAKRABORTY M , Wansley EK, Carrasquillo JA, Yu S, et al
    The use of chelated radionuclide (samarium-153-ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell-mediated killing.
    Clin Cancer Res. 2008;14:4241-9.
    PubMed     Related articles    Abstract available

  27. GARDNER ER , Dahut WL, Scripture CD, Jones J, et al
    Randomized crossover pharmacokinetic study of solvent-based paclitaxel and nab-paclitaxel.
    Clin Cancer Res. 2008;14:4200-5.
    PubMed     Related articles    Abstract available

  28. MULLIGAN AM , Pinnaduwage D, Bull SB, O'Malley FP, et al
    Prognostic effect of basal-like breast cancers is time dependent: evidence from tissue microarray studies on a lymph node-negative cohort.
    Clin Cancer Res. 2008;14:4168-74.
    PubMed     Related articles    Abstract available

  29. SIHTO H , Lundin J, Lehtimaki T, Sarlomo-Rikala M, et al
    Molecular subtypes of breast cancers detected in mammography screening and outside of screening.
    Clin Cancer Res. 2008;14:4103-10.
    PubMed     Related articles    Abstract available

  30. HAYES MJ , Thomas D, Emmons A, Giordano TJ, et al
    Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast.
    Clin Cancer Res. 2008;14:4038-44.
    PubMed     Related articles    Abstract available


    Genes Chromosomes Cancer

  31. OLDENBURG RA , Kroeze-Jansema KH, Houwing-Duistermaat JJ, Bayley JP, et al
    Genome-wide linkage scan in Dutch hereditary non-BRCA1/2 breast cancer families identifies 9q21-22 as a putative breast cancer susceptibility locus.
    Genes Chromosomes Cancer. 2008.
    PubMed     Related articles    Abstract available


    Int J Radiat Oncol Biol Phys

  32. CORMACK RA , Devlin PM
    Brachytherapy partial breast irradiation: analyzing effect of source configurations on dose metrics relevant to toxicity.
    Int J Radiat Oncol Biol Phys. 2008;71:940-4.
    PubMed     Related articles    Abstract available

  33. PEZNER RD , Schultheiss TE, Paz IB
    Malignant phyllodes tumor of the breast: local control rates with surgery alone.
    Int J Radiat Oncol Biol Phys. 2008;71:710-3.
    PubMed     Related articles    Abstract available

  34. LIVI L , Saieva C, Borghesi S, Paoletti L, et al
    Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for early breast carcinoma.
    Int J Radiat Oncol Biol Phys. 2008;71:705-9.
    PubMed     Related articles    Abstract available


    J Biol Chem

  35. VAIDYA KS , Harihar S, Phadke PA, Stafford LJ, et al
    Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling.
    J Biol Chem. 2008.
    PubMed     Related articles    Abstract available

  36. BOURGUIGNON LY , Peyrollier K, Xia W, Gilad E, et al
    Hyaluronan-CD44 interaction activates stem cell marker, nanog, stat-3-mediated MDR1 gene expression and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.
    J Biol Chem. 2008;.
    PubMed     Related articles    Abstract available   Free Full Text


    J Clin Oncol

  37. PUSZTAI L , Broglio K, Andre F, Symmans WF, et al
    Effect of Molecular Disease Subsets on Disease-Free Survival in Randomized Adjuvant Chemotherapy Trials for Estrogen-Receptor Positive Breast Cancer.
    J Clin Oncol. 2008.
    PubMed     Related articles    Abstract available


    J Natl Cancer Inst

  38. RYBERG M , Nielsen D, Cortese G, Nielsen G, et al
    New Insight Into Epirubicin Cardiac Toxicity: Competing Risks Analysis of 1097 Breast Cancer Patients.
    J Natl Cancer Inst. 2008.
    PubMed     Related articles    Abstract available

  39. GRIL B , Palmieri D, Bronder JL, Herring JM, et al
    Effect of Lapatinib on the Outgrowth of Metastatic Breast Cancer Cells to the Brain.
    J Natl Cancer Inst. 2008.
    PubMed     Related articles    Abstract available

  40. HOFVIND S , Vacek PM, Skelly J, Weaver DL, et al
    Comparing Screening Mammography for Early Breast Cancer Detection in Vermont and Norway.
    J Natl Cancer Inst. 2008.
    PubMed     Related articles    Abstract available

  41. HEDE K
    Possible MRI-Mastectomy Link Sparks Debate on MRI's Role in Breast Cancer Management.
    J Natl Cancer Inst. 2008.
    PubMed     Related articles   

  42. SINHA G
    Gene Testing To Tailor Breast Cancer Therapy Has Arrived--Is It Ready for the Clinic?
    J Natl Cancer Inst. 2008.
    PubMed     Related articles   

  43. GHOUSSAINI M , Song H, Koessler T, Al Olama AA, et al
    Multiple loci with different cancer specificities within the 8q24 gene desert.
    J Natl Cancer Inst. 2008;100:962-6.
    PubMed     Related articles    Abstract available

  44. COLDITZ GA , Winn DM
    Criteria for the evaluation of large cohort studies: an application to the nurses' health study.
    J Natl Cancer Inst. 2008;100:918-25.
    PubMed     Related articles    Abstract available

  45. BENOWITZ S
    Revised guidelines signal that gene expression profiles are coming of age.
    J Natl Cancer Inst. 2008;100:916-7.
    PubMed     Related articles   

  46. ROSS K
    Mapping pathways from stress to cancer progression.
    J Natl Cancer Inst. 2008;100:914-5.
    PubMed     Related articles   


    J Nucl Med

  47. NAYAK TK , Hathaway HJ, Ramesh C, Arterburn JB, et al
    Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers.
    J Nucl Med. 2008;49:978-86.
    PubMed     Related articles    Abstract available


    Lancet Oncol

  48. GELMON K
    Part II: Milestones in personalised medicine--trastuzumab.
    Lancet Oncol. 2008;9:698.
    PubMed     Related articles   


    Oncogene

  49. KATSUNO Y , Hanyu A, Kanda H, Ishikawa Y, et al
    Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway.
    Oncogene. 2008.
    PubMed     Related articles    Abstract available

  50. ZHANG D , Shimizu T, Araki N, Hirota T, et al
    Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice.
    Oncogene. 2008;27:4305-14.
    PubMed     Related articles    Abstract available


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