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	Amedeo Prize 2008 The 21 Finalists

Autoimmune Disorders

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 67 articles: HTML format

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March 2008
1. OAK S , Gilliam LK, Landin-Olsson M, Torn C, et al
   The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes.
   Proc Natl Acad Sci U S A. 2008;.
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2. LI N , Zhao D, Kirschbaum M, Zhang C, et al
   HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen.
   Proc Natl Acad Sci U S A. 2008;105:4796-801.
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3. STERN JN , Keskin DB, Zhang H, Lv H, et al
   Amino acid copolymer-specific IL-10-secreting regulatory T cells that ameliorate autoimmune diseases in mice.
   Proc Natl Acad Sci U S A. 2008;.
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4. SCANLAN CN , Burton DR, Dwek RA
   Making autoantibodies safe.
   Proc Natl Acad Sci U S A. 2008;105:4081-2.
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5. COLLIN M , Shannon O, Bjorck L
   IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.
   Proc Natl Acad Sci U S A. 2008;.
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6. WANG J , Takeuchi H, Sonobe Y, Jin S, et al
   Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population.
   Proc Natl Acad Sci U S A. 2008;.
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   February 2008
7. YOSHIDA T , Jiang F, Honjo T, Okazaki T, et al
   PD-1 deficiency reveals various tissue-specific autoimmunity by H-2b and dose-dependent requirement of H-2g7 for diabetes in NOD mice.
   Proc Natl Acad Sci U S A. 2008;.
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8. CALZASCIA T , Pellegrini M, Lin A, Garza KM, et al
   CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.
   Proc Natl Acad Sci U S A. 2008;.
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9. JOHANSSON F , Kramer F, Barnhart S, Kanter JE, et al
   Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.
   Proc Natl Acad Sci U S A. 2008;105:2082-7.
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10. JERU I , Duquesnoy P, Fernandes-Alnemri T, Cochet E, et al
    Mutations in NALP12 cause hereditary periodic fever syndromes.
    Proc Natl Acad Sci U S A. 2008;105:1614-9.
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    January 2008
11. DERBINSKI J , Pinto S, Rosch S, Hexel K, et al
    Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism.
    Proc Natl Acad Sci U S A. 2008;105:657-62.
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    December 2007
12. BOUAZIZ JD , Yanaba K, Venturi GM, Wang Y, et al
    Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice.
    Proc Natl Acad Sci U S A. 2007;104:20878-83.
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13. CHEN W , Zhang L, Liang B, Saenger Y, et al
    Perceiving the avidity of T cell activation can be translated into peripheral T cell regulation.
    Proc Natl Acad Sci U S A. 2007;104:20472-7.
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14. DELUCA GC , Ramagopalan SV, Herrera BM, Dyment DA, et al
    An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus.
    Proc Natl Acad Sci U S A. 2007;.
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15. XIE T , Chen M, Zhang QH, Ma Z, et al
    Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.
    Proc Natl Acad Sci U S A. 2007;104:19601-6.
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16. YU X , Sun JP, He Y, Guo X, et al
    Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.
    Proc Natl Acad Sci U S A. 2007;.
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    November 2007
17. DE WET H , Rees MG, Shimomura K, Aittoniemi J, et al
    Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes.
    Proc Natl Acad Sci U S A. 2007;104:18988-92.
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18. EMRE Y , Hurtaud C, Karaca M, Nubel T, et al
    Role of uncoupling protein UCP2 in cell-mediated immunity: How macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2007;.
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19. ODOARDI F , Kawakami N, Klinkert WE, Wekerle H, et al
    Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease.
    Proc Natl Acad Sci U S A. 2007;.
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20. FEUERER M , Jiang W, Holler PD, Satpathy A, et al
    Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2007;.
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21. GRAY DH , Gavanescu I, Benoist C, Mathis D, et al
    Danger-free autoimmune disease in Aire-deficient mice.
    Proc Natl Acad Sci U S A. 2007;.
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    October 2007
22. BEN-DAVID H , Sharabi A, Dayan M, Sela M, et al
    The role of CD8+CD28 regulatory cells in suppressing myasthenia gravis-associated responses by a dual altered peptide ligand.
    Proc Natl Acad Sci U S A. 2007;.
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23. WENZLAU JM , Juhl K, Yu L, Moua O, et al
    The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes.
    Proc Natl Acad Sci U S A. 2007;.
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24. NOVAK BJ , Blake DR, Meinardi S, Rowland FS, et al
    Exhaled methyl nitrate as a noninvasive marker of hyperglycemia in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2007;104:15613-8.
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    September 2007
25. LACY-HULBERT A , Smith AM, Tissire H, Barry M, et al
    Ulcerative colitis and autoimmunity induced by loss of myeloid {alpha}v integrins.
    Proc Natl Acad Sci U S A. 2007;.
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26. TIWARI-WOODRUFF S , Morales LB, Lee R, Voskuhl RR, et al
    Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment.
    Proc Natl Acad Sci U S A. 2007;104:14813-8.
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    August 2007
27. GRAY M , Miles K, Salter D, Gray D, et al
    Apoptotic cells protect mice from autoimmune inflammation by the induction of regulatory B cells.
    Proc Natl Acad Sci U S A. 2007;.
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28. TAI X , Van Laethem F, Sharpe AH, Singer A, et al
    Induction of autoimmune disease in CTLA-4-/- mice depends on a specific CD28 motif that is required for in vivo costimulation.
    Proc Natl Acad Sci U S A. 2007;.
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29. KOULMANDA M , Budo E, Bonner-Weir S, Qipo A, et al
    Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts.
    Proc Natl Acad Sci U S A. 2007;104:13074-9.
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    June 2007
30. TEUSCHER C , Subramanian M, Noubade R, Gao JF, et al
    Central histamine H3 receptor signaling negatively regulates susceptibility to autoimmune inflammatory disease of the CNS.
    Proc Natl Acad Sci U S A. 2007;.
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    May 2007
31. PIAGGIO E , Mars LT, Cassan C, Cabarrocas J, et al
    Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.
    Proc Natl Acad Sci U S A. 2007;104:9393-8.
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32. KWAN KY , Greenwald RJ, Mohanty S, Sharpe AH, et al
    Development of autoimmunity in mice lacking DNA topoisomerase 3beta.
    Proc Natl Acad Sci U S A. 2007;104:9242-7.
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33. OLIVEIRA JB , Bidere N, Niemela JE, Zheng L, et al
    NRAS mutation causes a human autoimmune lymphoproliferative syndrome.
    Proc Natl Acad Sci U S A. 2007;104:8953-8958.
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34. KOMATSU N , Hori S
    Full restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimeras.
    Proc Natl Acad Sci U S A. 2007;104:8959-64.
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35. FORTE M , Gold BG, Marracci G, Chaudhary P, et al
    Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2007;104:7558-63.
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    April 2007
36. CLATWORTHY MR , Willcocks L, Urban B, Langhorne J, et al
    Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.
    Proc Natl Acad Sci U S A. 2007;104:7169-74.
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37. GRAHAM RR , Kyogoku C, Sigurdsson S, Vlasova IA, et al
    Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
    Proc Natl Acad Sci U S A. 2007;104:6758-63.
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38. MAZARI L , Ouarzane M, Zouali M
    Subversion of B lymphocyte tolerance by hydralazine, a potential mechanism for drug-induced lupus.
    Proc Natl Acad Sci U S A. 2007;104:6317-22.
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39. YOU S , Leforban B, Garcia C, Bach JF, et al
    Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment.
    Proc Natl Acad Sci U S A. 2007;104:6335-40.
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    March 2007
40. JAMES LC , Keeble AH, Khan Z, Rhodes DA, et al
    Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function.
    Proc Natl Acad Sci U S A. 2007;.
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41. FABIS MJ , Scott GS, Kean RB, Koprowski H, et al
    Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models.
    Proc Natl Acad Sci U S A. 2007;104:5656-61.
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42. DOTTA F , Censini S, van Halteren AG, Marselli L, et al
    Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.
    Proc Natl Acad Sci U S A. 2007;104:5115-20.
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43. NAIT-OUMESMAR B , Picard-Riera N, Kerninon C, Decker L, et al
    Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors.
    Proc Natl Acad Sci U S A. 2007;104:4694-9.
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44. GAVANESCU I , Kessler B, Ploegh H, Benoist C, et al
    Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity.
    Proc Natl Acad Sci U S A. 2007;104:4583-7.
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45. WU H , Boackle SA, Hanvivadhanakul P, Ulgiati D, et al
    Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2007;104:3961-6.
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    February 2007
46. LUO X , Tarbell KV, Yang H, Pothoven K, et al
    Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.
    Proc Natl Acad Sci U S A. 2007;104:2821-6.
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47. ZHANG C , Todorov I, Lin CL, Atkinson M, et al
    Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice.
    Proc Natl Acad Sci U S A. 2007;104:2337-42.
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48. KIM S , Millet I, Kim HS, Kim JY, et al
    NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice.
    Proc Natl Acad Sci U S A. 2007;104:1913-8.
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    January 2007
49. NELSON JL , Gillespie KM, Lambert NC, Stevens AM, et al
    Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet beta cell microchimerism.
    Proc Natl Acad Sci U S A. 2007;104:1637-42.
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50. RADU CG , Shu CJ, Shelly SM, Phelps ME, et al
    Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis.
    Proc Natl Acad Sci U S A. 2007;.
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51. DE JERSEY J , Snelgrove SL, Palmer SE, Teteris SA, et al
    Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice.
    Proc Natl Acad Sci U S A. 2007;104:1295-300.
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52. MICHOU L , Lasbleiz S, Rat AC, Migliorini P, et al
    Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.
    Proc Natl Acad Sci U S A. 2007;.
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53. BENSING S , Fetissov SO, Mulder J, Perheentupa J, et al
    Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1.
    Proc Natl Acad Sci U S A. 2007;.
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54. ODOARDI F , Kawakami N, Li Z, Cordiglieri C, et al
    Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis.
    Proc Natl Acad Sci U S A. 2007;.
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    December 2006
55. KOWAL C , Degiorgio LA, Lee JY, Edgar MA, et al
    Human lupus autoantibodies against NMDA receptors mediate cognitive impairment.
    Proc Natl Acad Sci U S A. 2006;.
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56. ZHOU D , Srivastava R, Nessler S, Grummel V, et al
    Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2006;.
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    November 2006
57. URICH E , Gutcher I, Prinz M, Becher B, et al
    Autoantibody-mediated demyelination depends on complement activation but not activatory Fc-receptors.
    Proc Natl Acad Sci U S A. 2006;.
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58. BEN-DAVID H , Aruna BV, Seger R, Sela M, et al
    A 50-kDa ERK-like protein is up-regulated by a dual altered peptide ligand that suppresses myasthenia gravis-associated responses.
    Proc Natl Acad Sci U S A. 2006;.
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59. KEYMEULEN B , Gillard P, Mathieu C, Movahedi B, et al
    Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft.
    Proc Natl Acad Sci U S A. 2006;103:17444-9.
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60. LEE RH , Seo MJ, Reger RL, Spees JL, et al
    Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice.
    Proc Natl Acad Sci U S A. 2006;103:17438-43.
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61. BEETON C , Wulff H, Standifer NE, Azam P, et al
    Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.
    Proc Natl Acad Sci U S A. 2006;.
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    October 2006
62. NARENDRAN P , Neale AM, Lee BH, Ngui K, et al
    Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.
    Proc Natl Acad Sci U S A. 2006;103:16430-5.
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63. CHEN Z , Stockton J, Mathis D, Benoist C, et al
    Modeling CTLA4-linked autoimmunity with RNA interference in mice.
    Proc Natl Acad Sci U S A. 2006;.
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    September 2006
64. ALY TA , Ide A, Jahromi MM, Barker JM, et al
    Extreme genetic risk for type 1A diabetes.
    Proc Natl Acad Sci U S A. 2006;103:14074-9.
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    August 2006
65. BERKOWITZ P , Hu P, Warren S, Liu Z, et al
    p38MAPK inhibition prevents disease in pemphigus vulgaris mice.
    Proc Natl Acad Sci U S A. 2006;103:12855-60.
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66. CHAPARRO RJ , Konigshofer Y, Beilhack GF, Shizuru JA, et al
    Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.
    Proc Natl Acad Sci U S A. 2006;103:12475-80.
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67. DONATH MY , Ehses JA
    Type 1, type 1.5, and type 2 diabetes: NOD the diabetes we thought it was.
    Proc Natl Acad Sci U S A. 2006;103:12217-8.
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