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Autoimmune Disorders

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 77 articles: HTML format Text format

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February 2010
1. WURTMANN EJ , Wolin SL
   A role for a bacterial ortholog of the Ro autoantigen in starvation-induced rRNA degradation.
   Proc Natl Acad Sci U S A. 2010.
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2. MAVERAKIS E , Menezes JS, Ametani A, Han M, et al
   Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity.
   Proc Natl Acad Sci U S A. 2010;107:2550-5.
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3. BHAT R , Axtell R, Mitra A, Miranda M, et al
   Inhibitory role for GABA in autoimmune inflammation.
   Proc Natl Acad Sci U S A. 2010;107:2580-5.
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   January 2010
4. TRIANTAFYLLOPOULOU A , Franzke CW, Seshan SV, Perino G, et al
   Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages.
   Proc Natl Acad Sci U S A. 2010.
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5. HUMRICH JY , Morbach H, Undeutsch R, Enghard P, et al
   Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.
   Proc Natl Acad Sci U S A. 2010;107:204-9.
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6. JAIN N , Nguyen H, Chambers C, Kang J, et al
   Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity.
   Proc Natl Acad Sci U S A. 2010.
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   December 2009
7. KIHARA Y , Matsushita T, Kita Y, Uematsu S, et al
   Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis.
   Proc Natl Acad Sci U S A. 2009.
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8. JACOBS JP , Wu HJ, Benoist C, Mathis D, et al
   IL-17-producing T cells can augment autoantibody-induced arthritis.
   Proc Natl Acad Sci U S A. 2009.
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   November 2009
9. BECK-ENGESER GB , Eilat D, Harrer T, Jack HM, et al
   Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir.
   Proc Natl Acad Sci U S A. 2009.
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10. ZHANG H , Liu J, Li CR, Momen B, et al
    Deletion of Drosophila insulin-like peptides causes growth defects and metabolic abnormalities.
    Proc Natl Acad Sci U S A. 2009;106:19617-22.
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11. GRANT CK , Fink EA, Sundstrom M, Torbett BE, et al
    Improved health and survival of FIV-infected cats is associated with the presence of autoantibodies to the primary receptor, CD134.
    Proc Natl Acad Sci U S A. 2009.
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12. HORWITZ MS , Efrat S, Christen U, von Herrath MG, et al
    Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in {beta} cells prevent autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2009.
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    October 2009
13. MUTSKOV V , Felsenfeld G
    The human insulin gene is part of a large open chromatin domain specific for human islets.
    Proc Natl Acad Sci U S A. 2009;106:17419-24.
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14. SKIHAR V , Silva C, Chojnacki A, Doring A, et al
    Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate.
    Proc Natl Acad Sci U S A. 2009.
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15. LU Y , Song S
    Distinct immune responses to transgene products from rAAV1 and rAAV8 vectors.
    Proc Natl Acad Sci U S A. 2009;106:17158-62.
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    September 2009
16. BINSTADT BA , Hebert JL, Ortiz-Lopez A, Bronson R, et al
    The same systemic autoimmune disease provokes arthritis and endocarditis via distinct mechanisms.
    Proc Natl Acad Sci U S A. 2009;106:16758-63.
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17. YOKOYAMA S , Watanabe N, Sato N, Perera PY, et al
    Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes.
    Proc Natl Acad Sci U S A. 2009;106:15849-54.
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18. TODD JA
    Stem cells and a cure for type 1 diabetes?
    Proc Natl Acad Sci U S A. 2009;106:15523-4.
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    August 2009
19. MAEHR R , Chen S, Snitow M, Ludwig T, et al
    Generation of pluripotent stem cells from patients with type 1 diabetes.
    Proc Natl Acad Sci U S A. 2009.
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20. BLOCK K , Gorin Y, Abboud HE
    Subcellular localization of Nox4 and regulation in diabetes.
    Proc Natl Acad Sci U S A. 2009;106:14385-90.
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21. STEGBAUER J , Lee DH, Seubert S, Ellrichmann G, et al
    Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system.
    Proc Natl Acad Sci U S A. 2009.
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22. PLATTEN M , Youssef S, Hur EM, Ho PP, et al
    Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.
    Proc Natl Acad Sci U S A. 2009.
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23. MADI A , Hecht I, Bransburg-Zabary S, Merbl Y, et al
    Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data.
    Proc Natl Acad Sci U S A. 2009.
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    July 2009
24. VON ALLMEN CE , Schmitz N, Bauer M, Hinton HJ, et al
    Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells.
    Proc Natl Acad Sci U S A. 2009;106:11673-8.
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25. KAMANAKA M , Rainbow D, Schuster-Gossler K, Eynon EE, et al
    Amino acid polymorphisms altering the glycosylation of IL-2 do not protect from type 1 diabetes in the NOD mouse.
    Proc Natl Acad Sci U S A. 2009;106:11236-40.
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26. KONO DH , Haraldsson MK, Lawson BR, Pollard KM, et al
    Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus.
    Proc Natl Acad Sci U S A. 2009.
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    June 2009
27. SAWALHA AH
    Xq28 and lupus: IRAK1 or MECP2?
    Proc Natl Acad Sci U S A. 2009;106:E62.
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28. BRYNEDAL B , Bomfim IL, Olsson T, Duvefelt K, et al
    Differential expression, and genetic association, of CD58 in Swedish multiple sclerosis patients.
    Proc Natl Acad Sci U S A. 2009;106:E58.
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    May 2009
29. KREMER D , Heinen A, Jadasz J, Gottle P, et al
    p57kip2 is dynamically regulated in experimental autoimmune encephalomyelitis and interferes with oligodendroglial maturation.
    Proc Natl Acad Sci U S A. 2009.
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30. STEINMAN L
    The gray aspects of white matter disease in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2009;106:8083-4.
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    April 2009
31. DERFUSS T , Parikh K, Velhin S, Braun M, et al
    Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals.
    Proc Natl Acad Sci U S A. 2009.
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32. LINCOLN MR , Ramagopalan SV, Chao MJ, Herrera BM, et al
    Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.
    Proc Natl Acad Sci U S A. 2009.
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33. MARS LT , Araujo L, Kerschen P, Diem S, et al
    Invariant NKT cells inhibit development of the Th17 lineage.
    Proc Natl Acad Sci U S A. 2009;106:6238-43.
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    March 2009
34. ZAGURY D , Le Buanec H, Mathian A, Larcier P, et al
    IFNalpha kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model.
    Proc Natl Acad Sci U S A. 2009;106:5294-9.
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35. JACOB CO , Zhu J, Armstrong DL, Yan M, et al
    Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2009.
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36. TACKENBERG B , Jelcic I, Baerenwaldt A, Oertel WH, et al
    Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy.
    Proc Natl Acad Sci U S A. 2009;106:4788-92.
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37. WALLET MA , Flores RR, Wang Y, Yi Z, et al
    MerTK regulates thymic selection of autoreactive T cells.
    Proc Natl Acad Sci U S A. 2009;106:4810-5.
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38. LI S , Wang H, Peng B, Zhang M, et al
    Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
    Proc Natl Acad Sci U S A. 2009;106:4349-54.
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39. BECKLUND BR , Hansen DW Jr, Deluca HF
    Enhancement of 1,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis by calcitonin.
    Proc Natl Acad Sci U S A. 2009.
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40. BURGER D , Molnarfi N, Weber MS, Brandt KJ, et al
    Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1{beta} in human monocytes and multiple sclerosis.
    Proc Natl Acad Sci U S A. 2009.
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    February 2009
41. ALIMOHAMMADI M , Dubois N, Skoldberg F, Hallgren A, et al
    Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen.
    Proc Natl Acad Sci U S A. 2009.
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42. DAINICHI T , Kurono S, Ohyama B, Ishii N, et al
    Anti-laminin gamma-1 pemphigoid.
    Proc Natl Acad Sci U S A. 2009;106:2800-5.
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43. DE JAGER PL , Baecher-Allan C, Maier LM, Arthur AT, et al
    The role of the CD58 locus in multiple sclerosis.
    Proc Natl Acad Sci U S A. 2009.
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44. VERHAGEN J , Gabrysova L, Minaee S, Sabatos CA, et al
    Enhanced selection of FoxP3+ T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease.
    Proc Natl Acad Sci U S A. 2009.
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45. ARGAW AT , Gurfein BT, Zhang Y, Zameer A, et al
    VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown.
    Proc Natl Acad Sci U S A. 2009;106:1977-82.
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46. TAN YV , Abad C, Lopez R, Dong H, et al
    Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis.
    Proc Natl Acad Sci U S A. 2009.
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47. HAYASHI T , Gray CS, Chan M, Tawatao RI, et al
    Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7.
    Proc Natl Acad Sci U S A. 2009.
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    January 2009
48. BAUER M , Brakebusch C, Coisne C, Sixt M, et al
    {beta}1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity.
    Proc Natl Acad Sci U S A. 2009.
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49. BUBIER JA , Sproule TJ, Foreman O, Spolski R, et al
    A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB- Yaa mice.
    Proc Natl Acad Sci U S A. 2009.
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50. IEZZI G , Sonderegger I, Ampenberger F, Schmitz N, et al
    CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells.
    Proc Natl Acad Sci U S A. 2009;106:876-81.
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51. HERMISTON ML , Zikherman J, Tan AL, Lam VC, et al
    Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses.
    Proc Natl Acad Sci U S A. 2009;106:546-51.
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52. WU Y , Zheng Z, Jiang Y, Chess L, et al
    The specificity of T cell regulation that enables self-nonself discrimination in the periphery.
    Proc Natl Acad Sci U S A. 2009;106:534-9.
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    December 2008
53. D'ALISE AM , Auyeung V, Feuerer M, Nishio J, et al
    The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors.
    Proc Natl Acad Sci U S A. 2008;105:19857-62.
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54. LE SAOUT C , Mennechet S, Taylor N, Hernandez J, et al
    Memory-like CD8+ and CD4+ T cells cooperate to break peripheral tolerance under lymphopenic conditions.
    Proc Natl Acad Sci U S A. 2008;105:19414-9.
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55. LOUVET C , Szot GL, Lang J, Lee MR, et al
    Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice.
    Proc Natl Acad Sci U S A. 2008;105:18895-900.
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56. LU L , Kim HJ, Werneck MB, Cantor H, et al
    Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease.
    Proc Natl Acad Sci U S A. 2008.
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    November 2008
57. KORN T , Mitsdoerffer M, Croxford AL, Awasthi A, et al
    IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells.
    Proc Natl Acad Sci U S A. 2008;105:18460-5.
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58. QUINTANA FJ , Farez MF, Viglietta V, Iglesias AH, et al
    Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis.
    Proc Natl Acad Sci U S A. 2008.
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59. TERNESS P , Oelert T, Ehser S, Chuang JJ, et al
    Mitomycin C-treated dendritic cells inactivate autoreactive T cells: Toward the development of a tolerogenic vaccine in autoimmune diseases.
    Proc Natl Acad Sci U S A. 2008.
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    October 2008
60. KOULMANDA M , Bhasin M, Hoffman L, Fan Z, et al
    Curative and {beta} cell regenerative effects of {alpha}1-antitrypsin treatment in autoimmune diabetic NOD mice.
    Proc Natl Acad Sci U S A. 2008.
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61. KOH AS , Kuo AJ, Park SY, Cheung P, et al
    Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
    Proc Natl Acad Sci U S A. 2008.
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    September 2008
62. FABIS MJ , Phares TW, Kean RB, Koprowski H, et al
    Blood-brain barrier changes and cell invasion differ between therapeutic immune clearance of neurotrophic virus and CNS autoimmunity.
    Proc Natl Acad Sci U S A. 2008.
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63. LAI KWAN LAM Q , King Hung Ko O, Zheng BJ, Lu L, et al
    Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis.
    Proc Natl Acad Sci U S A. 2008;105:14993-8.
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64. KATO Z , Stern JN, Nakamura HK, Kuwata K, et al
    Positioning of autoimmune TCR-Ob.2F3 and TCR-Ob.3D1 on the MBP85-99/HLA-DR2 complex.
    Proc Natl Acad Sci U S A. 2008.
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65. ALBERT H , Collin M, Dudziak D, Ravetch JV, et al
    In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner.
    Proc Natl Acad Sci U S A. 2008.
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66. CROKER BA , Lawson BR, Berger M, Eidenschenk C, et al
    Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger.
    Proc Natl Acad Sci U S A. 2008.
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67. YU X , Park BH, Wang MY, Wang ZV, et al
    Making insulin-deficient type 1 diabetic rodents thrive without insulin.
    Proc Natl Acad Sci U S A. 2008;105:14070-5.
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68. SPOLSKI R , Kashyap M, Robinson C, Yu Z, et al
    IL-21 signaling is critical for the development of type I diabetes in the NOD mouse.
    Proc Natl Acad Sci U S A. 2008;105:14028-33.
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69. BAN L , Zhang J, Wang L, Kuhtreiber W, et al
    Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism.
    Proc Natl Acad Sci U S A. 2008;105:13644-9.
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70. MENCONI F , Monti MC, Greenberg DA, Oashi T, et al
    Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice.
    Proc Natl Acad Sci U S A. 2008.
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71. CHAO MJ , Barnardo MC, Lincoln MR, Ramagopalan SV, et al
    HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility.
    Proc Natl Acad Sci U S A. 2008;105:13069-74.
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72. GAVANESCU I , Benoist C, Mathis D
    B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: A therapeutic approach for APECED patients.
    Proc Natl Acad Sci U S A. 2008;105:13009-14.
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    August 2008
73. LI Q , Xu B, Michie SA, Rubins KH, et al
    Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.
    Proc Natl Acad Sci U S A. 2008;105:12439-44.
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74. PARK SG , Schimmel P, Kim S
    Aminoacyl tRNA synthetases and their connections to disease.
    Proc Natl Acad Sci U S A. 2008;105:11043-9.
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75. CORVOL JC , Pelletier D, Henry RG, Caillier SJ, et al
    Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event.
    Proc Natl Acad Sci U S A. 2008.
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76. LAOUAR Y , Town T, Jeng D, Tran E, et al
    TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis.
    Proc Natl Acad Sci U S A. 2008;105:10865-70.
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77. AHARONI R , Herschkovitz A, Eilam R, Blumberg-Hazan M, et al
    Demyelination arrest and remyelination induced by glatiramer acetate treatment of experimental autoimmune encephalomyelitis.
    Proc Natl Acad Sci U S A. 2008.
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