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Autoimmune Disorders

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December 2011
1. BONIFACIO E , Warncke K, Winkler C, Wallner M, et al
   Cesarean section and interferon-induced helicase gene polymorphisms combine to increase childhood type 1 diabetes risk.
   Diabetes. 2011;60:3300-6.
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   November 2011
2. YU L , Miao D, Scrimgeour L, Johnson K, et al
   Distinguishing Persistent Insulin Autoantibodies With Differential Risk: Nonradioactive Bivalent Proinsulin/Insulin Autoantibody Assay.
   Diabetes. 2011.
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3. CARVELLO M , Petrelli A, Vergani A, Lee KM, et al
   Inotuzumab Ozogamicin Murine Analog-Mediated B-Cell Depletion Reduces Anti-Islet Allo- and Autoimmune Responses.
   Diabetes. 2011.
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4. PFLUEGER M , Seppanen-Laakso T, Suortti T, Hyotylainen T, et al
   Age- and islet autoimmunity-associated differences in amino Acid and lipid metabolites in children at risk for type 1 diabetes.
   Diabetes. 2011;60:2740-7.
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5. LESLIE RD , Beyan H
   Metabolomics makes a mark: early changes associated with autoimmune diabetes.
   Diabetes. 2011;60:2688-90.
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6. SMYTH DJ , Cooper JD, Howson JM, Clarke P, et al
   FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection.
   Diabetes. 2011;60:3081-4.
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7. YANG P , Li HL, Wang CY
   FUT2 Nonfunctional Variant: A "Missing Link" Between Genes and Environment in Type 1 Diabetes?
   Diabetes. 2011;60:2685-7.
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8. COBELLI C , Renard E, Kovatchev B
   Artificial pancreas: past, present, future.
   Diabetes. 2011;60:2672-82.
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9. SCHATZ DA , Levine SR, Atkinson MA
   It's Time to Mow the GRAS in Type 1 Diabetes.
   Diabetes. 2011;60:2669-71.
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10. KIM DH , Perdomo G, Zhang T, Slusher S, et al
    FoxO6 integrates insulin signaling with gluconeogenesis in the liver.
    Diabetes. 2011;60:2763-74.
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11. LAMPRIANOU S , Immonen R, Nabuurs C, Gjinovci A, et al
    High-resolution magnetic resonance imaging quantitatively detects individual pancreatic islets.
    Diabetes. 2011;60:2853-60.
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    October 2011
12. LUCE S , Lemonnier F, Briand JP, Coste J, et al
    Single Insulin-Specific CD8+ T Cells Show Characteristic Gene Expression Profiles in Human Type 1 Diabetes.
    Diabetes. 2011.
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13. WANG X , Hao J, Metzger DL, Mui A, et al
    Early Treatment of NOD Mice With B7-H4 Reduces the Incidence of Autoimmune Diabetes.
    Diabetes. 2011.
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14. BOLO NR , Musen G, Jacobson AM, Weinger K, et al
    Brain Activation During Working Memory Is Altered in Type 1 Diabetes During Hypoglycemia.
    Diabetes. 2011.
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15. SANTIN I , Moore F, Colli ML, Gurzov EN, et al
    PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic {beta}-Cell Apoptosis via Regulation of the BH3-Only Protein Bim.
    Diabetes. 2011.
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16. COUGHLAN MT , Yap FY, Tong DC, Andrikopoulos S, et al
    Advanced glycation end products are direct modulators of beta-cell function.
    Diabetes. 2011;60:2523-32.
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17. YU L , Herold K, Krause-Steinrauf H, McGee PL, et al
    Rituximab selectively suppresses specific islet antibodies.
    Diabetes. 2011;60:2560-5.
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    September 2011
18. PERANTIE DC , Koller JM, Weaver PM, Lugar HM, et al
    Prospectively Determined Impact of Type 1 Diabetes on Brain Volume During Development.
    Diabetes. 2011.
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19. HOWARD AC , McNeil AK, Xiong F, Xiong WC, et al
    A Novel Cellular Defect in Diabetes: Membrane Repair Failure.
    Diabetes. 2011.
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20. SERREZE DV , Chapman HD, Niens M, Dunn R, et al
    Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell-Directed Type 1 Diabetes Therapies.
    Diabetes. 2011.
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21. LI Y , Ma J, Zhu H, Singh M, et al
    Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes.
    Diabetes. 2011.
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22. TIITU A , El-Osta A, Forsblom C, Sandholm N, et al
    Genetic Examination of SETD7 and SUV39H1/H2 Methyltransferases and the Risk of Diabetes Complications in Patients With Type 1 Diabetes.
    Diabetes. 2011.
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23. FERRARO A , Socci C, Stabilini A, Valle A, et al
    Expansion of Th17 Cells and Functional Defects in T Regulatory Cells Are Key Features of the Pancreatic Lymph Nodes in Patients With Type 1 Diabetes.
    Diabetes. 2011.
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24. OESER JK , Parekh VV, Wang Y, Jegadeesh NK, et al
    Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice.
    Diabetes. 2011.
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25. BUZZETTI R , Cernea S, Petrone A, Capizzi M, et al
    C-Peptide Response and HLA Genotypes in Subjects With Recent-Onset Type 1 Diabetes After Immunotherapy With DiaPep277: An Exploratory Study.
    Diabetes. 2011.
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26. HOLST JJ
    Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1.
    Diabetes. 2011;60:2203-5.
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27. HOWARD SG
    Comment on: Berhan. Thirty Years of Prospective Nationwide Incidence of Childhood Type 1 Diabetes: The Accelerating Increase by Time Tends to Level Off in Sweden. Diabetes 2011;60:577-581.
    Diabetes. 2011;60:e25.
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    August 2011
28. HOWSON JM , Rosinger S, Smyth DJ, Boehm BO, et al
    Genetic Analysis of Adult-Onset Autoimmune Diabetes.
    Diabetes. 2011.
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29. BLANTON D , Han Z, Bierschenk L, Linga-Reddy MV, et al
    Reduced Serum Vitamin D-Binding Protein Levels Are Associated With Type 1 Diabetes.
    Diabetes. 2011.
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30. HOWSON JM , Stevens H, Smyth DJ, Walker NM, et al
    Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct.
    Diabetes. 2011.
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31. SILVA DG , Daley SR, Hogan J, Lee SK, et al
    Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells.
    Diabetes. 2011;60:2102-11.
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32. MALLONE R , Brezar V
    To B or Not to B: (Anti)bodies of Evidence on the Crime Scene of Type 1 Diabetes?
    Diabetes. 2011;60:2020-2.
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33. STEFAN N , Haring HU
    The metabolically benign and malignant fatty liver.
    Diabetes. 2011;60:2011-7.
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34. NAITO M , Fujikura J, Ebihara K, Miyanaga F, et al
    Therapeutic Impact of Leptin on Diabetes, Diabetic Complications, and Longevity in Insulin-Deficient Diabetic Mice.
    Diabetes. 2011.
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    July 2011
35. DELONG T , Baker RL, Reisdorph N, Reisdorph R, et al
    Islet Amyloid Polypeptide Is a Target Antigen for Diabetogenic CD4+ T Cells.
    Diabetes. 2011.
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36. FERNANDEZ-VALVERDE SL , Taft RJ, Mattick JS
    MicroRNAs in {beta}-Cell Biology, Insulin Resistance, Diabetes and Its Complications.
    Diabetes. 2011;60:1825-31.
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    June 2011
37. HUGHSON A , Bromberg I, Johnson B, Quataert S, et al
    Uncoupling of Proliferation and Cytokines From Suppression Within the CD4+CD25+Foxp3+ T-Cell Compartment in the 1st Year of Human Type 1 Diabetes.
    Diabetes. 2011.
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38. THAYER TC , Delano M, Liu C, Chen J, et al
    Superoxide Production by Macrophages and T Cells Is Critical for the Induction of Autoreactivity and Type 1 Diabetes.
    Diabetes. 2011.
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39. ARIF S , Moore F, Marks K, Bouckenooghe T, et al
    Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated {beta}-Cell Death.
    Diabetes. 2011.
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40. IZE-LUDLOW D , Lightfoot YL, Parker M, Xue S, et al
    Progressive Erosion of {beta}-Cell Function Precedes the Onset of Hyperglycemia in the NOD Mouse Model of Type 1 Diabetes.
    Diabetes. 2011.
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41. BADAMI E , Sorini C, Coccia M, Usuelli V, et al
    Defective Differentiation of Regulatory FoxP3+ T Cells by Small-Intestinal Dendritic Cells in Patients With Type 1 Diabetes.
    Diabetes. 2011.
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42. SANDA S , Greenbaum CJ
    Comment on: Atkinson. It's Time to Consider Changing the Rules: The Rationale for Rethinking Control Groups in Clinical Trials Aimed at Reversing Type 1 Diabetes. Diabetes 2011;60:361-363.
    Diabetes. 2011;60:e17.
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    May 2011
43. GEROLD KD , Zheng P, Rainbow DB, Zernecke A, et al
    The Soluble CTLA-4 Splice Variant Protects From Type 1 Diabetes and Potentiates Regulatory T-Cell Function.
    Diabetes. 2011.
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44. KRAUSE MP , Moradi J, Nissar AA, Riddell MC, et al
    Inhibition of Plasminogen Activator Inhibitor-1 Restores Skeletal Muscle Regeneration in Untreated Type 1 Diabetic Mice.
    Diabetes. 2011.
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45. KACEROVSKY M , Jones J, Schmid AI, Barosa C, et al
    Postprandial and Fasting Hepatic Glucose Fluxes in Longstanding Type 1 Diabetes.
    Diabetes. 2011.
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46. ATKINSON MA , Bluestone JA, Eisenbarth GS, Hebrok M, et al
    How Does Type 1 Diabetes Develop?: The Notion of Homicide or {beta}-Cell Suicide Revisited.
    Diabetes. 2011;60:1370-9.
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    April 2011
47. WHITFIELD-LARRY F , Young EF, Talmage G, Fudge E, et al
    HLA-A2-Matched Peripheral Blood Mononuclear Cells From Type 1 Diabetic Patients, but not Nondiabetic Donors, Transfer Insulitis to NOD-scid/{gamma}cnull/HLA-A2 Transgenic Mice Concurrent With the Expansion of Islet-Specific CD8+ T cells.
    Diabetes. 2011.
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    March 2011
48. COOPER JD , Smyth DJ, Walker NM, Stevens H, et al
    Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes.
    Diabetes. 2011.
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49. KIELGAST U , Holst JJ, Madsbad S
    Antidiabetic Actions of Endogenous and Exogenous GLP-1 in Type 1 Diabetic Patients With and Without Residual {beta}-Cell Function.
    Diabetes. 2011.
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50. YONG J , Rasooly J, Dang H, Lu Y, et al
    Multimodality Imaging of {beta}-Cells in Mouse Models of Type I and II Diabetes.
    Diabetes. 2011.
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51. MCGUIRE HM , Walters S, Vogelzang A, Lee CM, et al
    Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models.
    Diabetes. 2011;60:867-75.
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52. GRUNNET LG , Mandrup-Poulsen T
    Cytokines and type 1 diabetes: a numbers game.
    Diabetes. 2011;60:697-9.
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53. GREENBAUM C , Atkinson MA
    Persistence is the Twin Sister of Excellence: An Important Lesson for Attempts to Prevent and Reverse Type 1 Diabetes.
    Diabetes. 2011;60:693-4.
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54. AKIRAV EM , Baquero MT, Opare-Addo LW, Akirav M, et al
    Glucose and inflammation control islet vascular density and beta-cell function in NOD mice: control of islet vasculature and vascular endothelial growth factor by glucose.
    Diabetes. 2011;60:876-83.
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    February 2011
55. NIENS M , Grier AE, Marron M, Kay TW, et al
    Prevention of "Humanized" Diabetogenic CD8 T-cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach.
    Diabetes. 2011.
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56. FOURLANOS S , Perry C, Gellert SA, Martinuzzi E, et al
    Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes.
    Diabetes. 2011.
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57. STECK AK , Armstrong TK, Babu SR, Eisenbarth GS, et al
    Stepwise or Linear Decrease in Penetrance of Type 1 Diabetes With Lower-Risk HLA Genotypes Over the Past 40 Years.
    Diabetes. 2011.
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58. DRIVER JP , Chen YG, Zhang W, Asrat S, et al
    Unmasking Genes in a Type 1 Diabetes-Resistant Mouse Strain That Enhances Pathogenic CD8 T-Cell Responses.
    Diabetes. 2011.
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59. SHAO CH , Capek HL, Patel KP, Wang M, et al
    Carbonylation Contributes to SERCA2a Activity Loss and Diastolic Dysfunction in a Rat Model of Type 1 Diabetes.
    Diabetes. 2011.
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60. AIDA K , Nishida Y, Tanaka S, Maruyama T, et al
    RIG-I- and MDA5-Initiated Innate Immunity Linked With Adaptive Immunity Accelerates {beta}-Cell Death in Fulminant Type 1 Diabetes.
    Diabetes. 2011.
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61. WINKLER C , Lauber C, Adler K, Grallert H, et al
    An Interferon-Induced Helicase (IFIH1) Gene Polymorphism Associates With Different Rates of Progression From Autoimmunity to Type 1 Diabetes.
    Diabetes. 2011;60:685-90.
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62. MEAGHER C , Cruikshank W, Delovitch TL
    Response to Comment on: Meagher et al. Neutralization of Interleukin-16 Protects Nonobese Diabetic Mice From Autoimmune Type 1 Diabetes by a CCL4-Dependent Mechanism. Diabetes 2010;59:2862-2871.
    Diabetes. 2011;60:e13.
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63. VENDRAME F , Dotta F
    Comment on: Meagher et al. Neutralization of Interleukin-16 Protects Nonobese Diabetic Mice From Autoimmune Type 1 Diabetes by a CCL4-Dependent Mechanism. Diabetes 2010;59:2862-2871.
    Diabetes. 2011;60:e12.
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64. POLAK JF , Backlund JY, Cleary PA, Harrington AP, et al
    Progression of Carotid Artery Intima-Media Thickness During 12 Years in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study.
    Diabetes. 2011;60:607-613.
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65. BERHAN Y , Waernbaum I, Lind T, Mollsten A, et al
    Thirty Years of Prospective Nationwide Incidence of Childhood Type 1 Diabetes: The Accelerating Increase by Time Tends to Level Off in Sweden.
    Diabetes. 2011;60:577-581.
    PubMed     Text format     Related articles    Abstract available
    
    
    
    
66. LEE Y , Wang MY, Du XQ, Charron MJ, et al
    Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice.
    Diabetes. 2011;60:391-7.
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67. EDGERTON DS , Cherrington AD
    Glucagon as a critical factor in the pathology of diabetes.
    Diabetes. 2011;60:377-80.
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68. ATKINSON MA
    It's Time to Consider Changing the Rules: The Rationale for Rethinking Control Groups in Clinical Trials Aimed at Reversing Type 1 Diabetes.
    Diabetes. 2011;60:361-3.
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    January 2011
69. SWAFFORD AD , Howson JM, Davison LJ, Wallace C, et al
    An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes.
    Diabetes. 2011.
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70. QIN H , Lee IF, Panagiotopoulos C, Wang X, et al
    Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling.
    Diabetes. 2011.
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71. MORAHAN G , Mehta M, James I, Chen WM, et al
    Tests for Genetic Interactions in Type 1 Diabetes: Linkage and Stratification Analyses of 4,422 Affected Sib-Pairs.
    Diabetes. 2011.
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72. LIN M , Murphy B, Medof ME, Segerer S, et al
    Response to Comment on: Lin et al. (2010) Immune Cell-Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin. Diabetes;59:2247-2252.
    Diabetes. 2011;60:e9.
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73. OSTERGAARD JA , Thiel S, Hansen TK, Rasch R, et al
    Comment on: Lin et al. (2010) Immune Cell-Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin. Diabetes;59: 2247-2252.
    Diabetes. 2011;60:e7-8.
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74. CRYER PE
    Elimination of hypoglycemia from the lives of people affected by diabetes.
    Diabetes. 2011;60:24-7.
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75. SKYLER JS , Ricordi C
    Stopping type 1 diabetes: attempts to prevent or cure type 1 diabetes in man.
    Diabetes. 2011;60:1-8.
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76. CAI CQ , Zhang T, Breslin MB, Giraud M, et al
    Both polymorphic variable number of tandem repeats and autoimmune regulator modulate differential expression of insulin in human thymic epithelial cells.
    Diabetes. 2011;60:336-44.
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    December 2010
77. HAMMAN RF
    Mortality risk in long-standing type 1 diabetes: hope and concern.
    Diabetes. 2010;59:2997-8.
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78. ROTHER KI , Harlan DM
    Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic {beta}-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846-2853.
    Diabetes. 2010;59:e26.
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    November 2010
79. COOPERBERG BA , Cryer PE
    Insulin reciprocally regulates glucagon secretion in humans.
    Diabetes. 2010;59:2936-40.
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80. COOPERBERG BA , Cryer PE
    Glucagon supports postabsorptive plasma glucose concentrations in humans with biologically optimal insulin levels.
    Diabetes. 2010;59:2941-4.
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    October 2010
81. BERTIN-MAGHIT S , Pang D, O'Sullivan B, Best S, et al
    IL-1{beta} produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T cells: implications for the timing of tolerizing immunotherapy.
    Diabetes. 2010.
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82. CHEN J , Gusdon AM, Piganelli J, Leiter EH, et al
    mt-Nd2a modifies resistance against autoimmune Type 1 diabetes in NOD mice at the level of the pancreatic beta cell.
    Diabetes. 2010.
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83. FRANC DT , Kodl CT, Mueller BA, Muetzel RL, et al
    High connectivity between reduced cortical thickness and disrupted white matter tracts in longstanding type 1 diabetes.
    Diabetes. 2010.
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84. LOPES-VIRELLA MF , Hunt KJ, Baker NL, Lachin J, et al
    The Levels of Oxidized LDL and AGE- LDL in Circulating Immune Complexes are strongly associated with increased levels of Carotid Intima-Media Thickness and its progression in Type 1 Diabetes.
    Diabetes. 2010.
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85. SCHAUER IE , Snell-Bergeon JK, Bergman BC, Maahs DM, et al
    Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: The CACTI study.
    Diabetes. 2010.
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86. BRAVARD A , Lefai E, Meugnier E, Pesenti S, et al
    FTO is increased in muscle during type 2 diabetes and its over-expression in myotubes alters insulin signalling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction.
    Diabetes. 2010.
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87. OIKARINEN S , Martiskainen M, Tauriainen S, Huhtala H, et al
    Enterovirus RNA in Blood Is Linked to the Development of Type 1 Diabetes.
    Diabetes. 2010.
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88. MCCRIMMON RJ , Sherwin RS
    Hypoglycemia in type 1 diabetes.
    Diabetes. 2010;59:2333-9.
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89. ZHOU L , Podolsky N, Sang Z, Ding Y, et al
    The medial amygdalar nucleus: a novel glucose-sensing region that modulates the counterregulatory response to hypoglycemia.
    Diabetes. 2010;59:2646-52.
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    September 2010
90. FOUSTERI G , Chan JR, Zheng Y, Whiting C, et al
    Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection.
    Diabetes. 2010.
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91. STENE LC , Oikarinen S, Hyoty H, Barriga KJ, et al
    Enterovirus Infection and Progression from Islet Autoimmunity to Type 1 Diabetes: The Diabetes and Autoimmunity Study in the Young (DAISY).
    Diabetes. 2010.
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92. JUREWICZ M , Yang S, Augello A, Godwin JG, et al
    Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes.
    Diabetes. 2010.
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93. ARNOLD E , Rivera JC, Thebault S, Moreno-Paramo D, et al
    HIGH LEVELS OF SERUM PROLACTIN PROTECT AGAINST DIABETIC RETINOPATHY BY INCREASING OCULAR VASOINHIBINS.
    Diabetes. 2010.
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94. VERGANI A , D'Addio F, Jurewicz M, Petrelli A, et al
    A Novel Clinically Relevant Strategy to Abrogate Autoimmunity and Regulate Alloimmunity in NOD Mice.
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