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The Medical Article of the Year 2008


  Arrhythmias

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Articles published in Br J Pharmacol

Retrieve available abstracts of 28 articles:
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Single Articles


    June 2008
  1. CHRIST T , Wettwer E, Voigt N, Hala O, et al
    Pathology-specific effects of the I(Kur)/I(to)/I(K,ACh) blocker AVE0118 on ion channels in human chronic atrial fibrillation.
    Br J Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


    May 2008
  2. SALAMA G , London B, Kerchner LJ, Salama NR, et al
    Sex differences in the expression of sodium/calcium exchanger influence the arrhythmia phenotype in the long QT syndrome type 2.
    Br J Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


  3. WANG YH , Shi CX, Dong F, Sheng JW, et al
    Inhibition of the rapid component of the delayed rectifier potassium current in ventricular myocytes by angiotensin II via the AT1 receptor.
    Br J Pharmacol. 2008;154:429-39.
    PubMed     Related articles    Abstract available


    February 2008
  4. TSANG S , Wu S, Liu J, Wong TM, et al
    Testosterone protects rat hearts against ischaemic insults by enhancing the effects of alpha(1)-adrenoceptor stimulation.
    Br J Pharmacol. 2008;153:693-709.
    PubMed     Related articles    Abstract available


  5. GALINDO-TOVAR A , Kaumann AJ
    Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac beta(1)-adrenoceptors.
    Br J Pharmacol. 2008;153:710-20.
    PubMed     Related articles    Abstract available


  6. VAN DER HEYDEN MA , Smits ME, Vos MA
    Drugs and trafficking of ion channels: a new pro-arrhythmic threat on the horizon?
    Br J Pharmacol. 2008;153:406-9.
    PubMed     Related articles    Abstract available   Free Full Text


    January 2008
  7. HEUSCH G
    Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: benefit from selective bradycardic agents.
    Br J Pharmacol. 2008;.
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    December 2007
  8. YEH YH , Qi X, Shiroshita-Takeshita A, Liu J, et al
    Atrial tachycardia induces remodelling of muscarinic receptors and their coupled potassium currents in canine left atrial and pulmonary vein cardiomyocytes.
    Br J Pharmacol. 2007;152:1021-32.
    PubMed     Related articles    Abstract available


  9. MICHAEL G , Dempster J, Kane KA, Coker SJ, et al
    Potentiation of E-4031-induced torsade de pointes by HMR1556 or ATX-II is not predicted by action potential short-term variability or triangulation.
    Br J Pharmacol. 2007;152:1215-27.
    PubMed     Related articles    Abstract available


    November 2007
  10. CHEN YJ , Chen YC, Wongcharoen W, Lin CI, et al
    Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes.
    Br J Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


    October 2007
  11. TAKEMASA H , Nagatomo T, Abe H, Kawakami K, et al
    Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome.
    Br J Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  12. VINCZE D , Farkas AS, Rudas L, Makra P, et al
    Relevance of anaesthesia for dofetilide-induced torsades de pointes in alpha(1)-adrenoceptor-stimulated rabbits.
    Br J Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


    September 2007
  13. JAMES AF , Hancox JC
    More types than one: multiple muscarinic receptor coupled K(+) currents undergo remodelling in an experimental model of atrial fibrillation.
    Br J Pharmacol. 2007;.
    PubMed     Related articles    Abstract available   Free Full Text


    August 2007
  14. STORK D , Timin EN, Berjukow S, Huber C, et al
    State dependent dissociation of HERG channel inhibitors.
    Br J Pharmacol. 2007;151:1368-76.
    PubMed     Related articles    Abstract available


  15. THOMSEN MB
    Double pharmacological challenge on repolarization opens new avenues for drug safety research.
    Br J Pharmacol. 2007;151:909-11.
    PubMed     Related articles    Abstract available


  16. LENGYEL C , Varro A, Tabori K, Papp JG, et al
    Combined pharmacological block of I(Kr) and I(Ks) increases short-term QT interval variability and provokes torsades de pointes.
    Br J Pharmacol. 2007;151:941-51.
    PubMed     Related articles    Abstract available


    June 2007
  17. VAN STEEG TJ , Freijer J, Danhof M, de Lange EC, et al
    Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint.
    Br J Pharmacol. 2007;151:356-66.
    PubMed     Related articles    Abstract available


    April 2007
  18. PABLA R , Curtis MJ
    Nitric oxide fails to confer endogenous antiarrhythmic cardioprotection in the primate heart in vitro.
    Br J Pharmacol. 2007;150:893-8.
    PubMed     Related articles    Abstract available


    February 2007
  19. DA CUNHA DN , Hamlin RL, Billman GE, Carnes CA, et al
    n-3 (omega-3) polyunsaturated fatty acids prevent acute atrial electrophysiological remodeling.
    Br J Pharmacol. 2007;150:281-5.
    PubMed     Related articles    Abstract available


    December 2006
  20. OPTHOF T , Den Ruijter HM
    omega-3 Polyunsaturated fatty acids (PUFAs or fish oils) and atrial fibrillation.
    Br J Pharmacol. 2006;.
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  21. LAWRENCE CL , Bridgland-Taylor MH, Pollard CE, Hammond TG, et al
    A rabbit Langendorff heart proarrhythmia model: predictive value for clinical identification of Torsades de Pointes.
    Br J Pharmacol. 2006;149:845-60.
    PubMed     Related articles    Abstract available


  22. GARCIA-RIVAS GDE J , Carvajal K, Correa F, Zazueta C, et al
    Ru360, a specific mitochondrial calcium uptake inhibitor, improves cardiac post-ischaemic functional recovery in rats in vivo.
    Br J Pharmacol. 2006;149:829-37.
    PubMed     Related articles    Abstract available


    November 2006
  23. THOMSEN MB , Beekman JD, Attevelt NJ, Takahara A, et al
    No proarrhythmic properties of the antibiotics Moxifloxacin or Azithromycin in anaesthetized dogs with chronic-AV block.
    Br J Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


    October 2006
  24. BAKER KE , Wood LM, Whittaker M, Curtis MJ, et al
    Nupafant, a PAF-antagonist prototype for suppression of ventricular fibrillation without liability for QT prolongation?
    Br J Pharmacol. 2006;.
    PubMed     Related articles   


  25. CLEMENTS-JEWERY H
    Mitochondria, the calcium uniporter, and reperfusion-induced ventricular fibrillation.
    Br J Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  26. KORTE T , Grohe C
    Sex hormones and arrhythmia in myocardial ischemia.
    Br J Pharmacol. 2006;149:227-8.
    PubMed     Related articles    Abstract available   Free Full Text


    May 2006
  27. LOOI YH , Kane KA, McPhaden AR, Wainwright CL, et al
    Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats.
    Br J Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


    August 2005
  28. TAKAHARA A , Sugiyama A, Hashimoto K
    Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation.
    Br J Pharmacol 2005;.
    PubMed     Related articles    Abstract available   Free Full Text


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