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  Alzheimer's Disease

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Articles published in Neuroscience

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    February 2015
  1. GUO HB, Cheng YF, Wu JG, Wang CM, et al
    Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation.
    Neuroscience. 2015 Feb 4. pii: S0306-4522(15)00116.
    PubMed     Text format     Abstract available


    January 2015
  2. SETHI M, Joshi SS, Webb RL, Beckett TL, et al
    Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer's disease.
    Neuroscience. 2015 Jan 28. pii: S0306-4522(15)00090.
    PubMed     Text format     Abstract available


  3. RODRIGUEZ-ARELLANO JJ, Parpura V, Zorec R, Verkhratsky A, et al
    Astrocytes in physiological ageing and Alzheimers disease.
    Neuroscience. 2015 Jan 13. pii: S0306-4522(15)00031.
    PubMed     Text format     Abstract available


    December 2014
  4. CORREA MS, Vedovelli K, Giacobbo BL, Bruhn de Souza CE, et al
    Psychophysiological Correlates of Cognitive Deficits in Family Caregivers of patients with Alzheimer Disease.
    Neuroscience. 2014 Dec 6. pii: S0306-4522(14)01020.
    PubMed     Text format     Abstract available


  5. BORN HA
    Seizures in Alzheimer's disease.
    Neuroscience. 2014 Dec 4. pii: S0306-4522(14)01019.
    PubMed     Text format     Abstract available


    October 2014
  6. WALKER DG, Whetzel AM, Lue LF
    Expression of suppressor of cytokine signaling (SOCS) genes in human elderly and alzheimer's disease brains and human microglia.
    Neuroscience. 2014 Oct 3. pii: S0306-4522(14)00803.
    PubMed     Text format     Abstract available


  7. LATTA CH, Brothers HM, Wilcock DM
    Neuroinflammation in Alzheimer's disease; a source of heterogeneity and target for personalized therapy.
    Neuroscience. 2014 Oct 3. pii: S0306-4522(14)00820.
    PubMed     Text format     Abstract available


  8. LUE LF, Schmitz C, Walker DG
    What happens to microglial TREM2 in Alzheimer's disease: immunoregulatory turned into immunopathogenic?
    Neuroscience. 2014 Oct 1. pii: S0306-4522(14)00801.
    PubMed     Text format     Abstract available


    September 2014
  9. PARSI S, Pandamooz S, Heidari S, Naji M, et al
    A novel rat model of Alzheimer's disease based on Lentiviral-mediated expression of mutant APP.
    Neuroscience. 2014 Sep 27. pii: S0306-4522(14)00796.
    PubMed     Text format     Abstract available


  10. HASCALOVICI JR, Song W, Liberman A, Vaya J, et al
    Neural HO-1/sterol interactions in vivo: Implications for Alzheimer's disease.
    Neuroscience. 2014 Sep 9. pii: S0306-4522(14)00741.
    PubMed     Text format     Abstract available


  11. CHEN X, Hu J, Jiang L, Xu S, et al
    Brilliant Blue G improves cognition in an animal model of Alzheimer's disease and inhibits amyloid-beta-induced loss of filopodia and dendrite spines in hippocampal neurons.
    Neuroscience. 2014 Sep 3. pii: S0306-4522(14)00713.
    PubMed     Text format     Abstract available


    August 2014
  12. FERNANDEZ-ECHEVARRIA C, Diaz M, Ferrer I, Canerina-Amaro A, et al
    Abeta promotes VDAC1 channel dephosphorylation in neuronal lipid rafts. Relevance to the mechanisms of neurotoxicity in Alzheimer's Disease.
    Neuroscience. 2014 Aug 25. pii: S0306-4522(14)00701.
    PubMed     Text format     Abstract available


  13. ZAMBERLAN DC, Arantes LP, Machado ML, Golombieski R, et al
    Diphenyl-diselenide suppresses amyloid-beta peptide in Caenorhabditis elegans model of Alzheimer's disease.
    Neuroscience. 2014 Aug 14. pii: S0306-4522(14)00645.
    PubMed     Text format     Abstract available


    July 2014
  14. LIU MY, Wang S, Yao WF, Zhang ZJ, et al
    Memantine improves spatial learning and memory impairments by regulating NGF signaling in APP/PS1 transgenic mice.
    Neuroscience. 2014;273:141-51.
    PubMed     Text format     Abstract available


  15. BRASKIE MN, Boyle CP, Rajagopalan P, Gutman BA, et al
    Physical activity, inflammation, and volume of the aging brain.
    Neuroscience. 2014;273:199-209.
    PubMed     Text format     Abstract available


    June 2014
  16. ZHAO ZB, Wu L, Xiong R, Wang LL, et al
    MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease.
    Neuroscience. 2014 Jun 17. pii: S0306-4522(14)00498.
    PubMed     Text format     Abstract available


  17. MORRIS JK, Vidoni ED, Perea RD, Rada R, et al
    Insulin resistance and gray matter volume in neurodegenerative disease.
    Neuroscience. 2014;270:139-47.
    PubMed     Text format     Abstract available


  18. DONG Z, Yan L, Huang G, Zhang L, et al
    Ibuprofen partially attenuates neurodegenerative symptoms in presenilin conditional double-knockout mice.
    Neuroscience. 2014;270:58-68.
    PubMed     Text format     Abstract available


    April 2014
  19. BEGGIATO S, Giuliani A, Sivilia S, Lorenzini L, et al
    CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice.
    Neuroscience. 2014;266:13-22.
    PubMed     Text format     Abstract available


  20. EL KADMIRI N, Zaid N, Zaid Y, Tadevosyan A, et al
    Novel Presenilins mutations within Moroccan patients with Early Onset Alzheimer's Disease.
    Neuroscience. 2014 Apr 3. pii: S0306-4522(14)00275.
    PubMed     Text format     Abstract available


  21. YAMAZAKI Y, Harada S, Tokuyama S
    Sodium-glucose transporter type 3-mediated neuroprotective effect of acetylcholine suppresses the development of cerebral ischemic neuronal damage.
    Neuroscience. 2014 Apr 1. pii: S0306-4522(14)00266.
    PubMed     Text format     Abstract available


    March 2014
  22. KANEMOTO S, Griffin J, Markham-Coultes K, Aubert I, et al
    Proliferation, differentiation and amyloid-beta production in neural progenitor cells isolated from TgCRND8 mice.
    Neuroscience. 2014;261:52-9.
    PubMed     Text format     Abstract available


    February 2014
  23. AMLIEN IK, Fjell AM
    Diffusion Tensor Imaging of White Matter Degeneration in Alzheimer's Disease and Mild Cognitive Impairment.
    Neuroscience. 2014 Feb 26. pii: S0306-4522(14)00121.
    PubMed     Text format     Abstract available


  24. NOH H, Seo H
    Age-dependent effects of valproic acid in Alzheimer's disease (AD) mice are associated with nerve growth factor (NGF) regulation.
    Neuroscience. 2014 Feb 22. pii: S0306-4522(14)00108.
    PubMed     Text format     Abstract available


  25. HATAYAMA Y, Hashimoto T, Kohayakawa H, Kiyoshi T, et al
    In vivo pharmacological characterization of AC-3933, a benzodiazepine receptor partial inverse agonist for the treatment of Alzheimer's disease.
    Neuroscience. 2014 Feb 7. pii: S0306-4522(14)00084.
    PubMed     Text format     Abstract available


    January 2014
  26. IZCO M, Martinez P, Corrales A, Fandos N, et al
    Changes in the brain and plasma Abeta peptides levels with age and its relationship with cognitive impairment in the APPswe/PS1dE9 mouse model of Alzheimer's disease.
    Neuroscience. 2014 Jan 18. pii: S0306-4522(14)00007.
    PubMed     Text format     Abstract available


  27. COFFEY EE, Beckel JM, Laties AM, Mitchell CH, et al
    Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP.
    Neuroscience. 2014 Jan 9. pii: S0306-4522(14)00005.
    PubMed     Text format     Abstract available


    December 2013

  28. Rretraction notice to ''1h-MRS can monitor metabolites changes of lateral intraventricular BDNF infusion into a mouse model of Alzheimer's disease in vivo'' [Neuroscience 245 (2013) 40-49].
    Neuroscience. 2013;254:477.
    PubMed     Text format    


  29. MARJANSKA M, Weigand SD, Preboske G, Wengenack TM, et al
    Treatment Effects in a Transgenic Mouse Model of Alzheimer's Disease: A Magnetic Resonance Spectroscopy Study after Passive Immunization.
    Neuroscience. 2013 Dec 3. pii: S0306-4522(13)00999.
    PubMed     Text format     Abstract available


    October 2013
  30. ZAHID S , Khan R, Oellerich M, Ahmed N, et al
    Differential S-nitrosylation of proteins in Alzheimer's disease.
    Neuroscience. 2013 Oct 21. pii: S0306-4522(13)00879.
    PubMed     Text format     Abstract available


    September 2013
  31. SCHREURS BG , Smith-Bell CA, Lemieux SK
    Dietary Cholesterol Increases Ventricular Volume and Narrows Cerebrovascular Diameter in a Rabbit Model of Alzheimer's Disease.
    Neuroscience. 2013 Sep 14. pii: S0306-4522(13)00786.
    PubMed     Text format     Abstract available


    July 2013
  32. YANG Y , Song W
    Molecular links between Alzheimer's disease and diabetes mellitus.
    Neuroscience. 2013 Jul 15. pii: S0306-4522(13)00584.
    PubMed     Text format     Abstract available


    June 2013
  33. MARTINS I, Gomes S, Costa RO, Otvos L, et al
    Leptin and ghrelin prevent hippocampal dysfunction induced by Abeta oligomers.
    Neuroscience. 2013;241:41-51.
    PubMed     Text format     Abstract available


    May 2013
  34. SHON JM , Lee DY, Seo EH, Sohn BK, et al
    Functional Neuroanatomical Correlates of the Executive Clock Drawing Task (Clox) Performance in Alzheimer's Disease: A Fdg-Pet Study.
    Neuroscience. 2013 May 11. pii: S0306-4522(13)00419.
    PubMed     Text format     Abstract available


    April 2013
  35. KRSTIC D , Pfister S, Notter T, Knuesel I, et al
    Decisive role of Reelin signaling during early stages of Alzheimer's Disease.
    Neuroscience. 2013 Apr 27. pii: S0306-4522(13)00367.
    PubMed     Text format     Abstract available


  36. ZHANG W , Wang PJ, Li MH, Gao XL, et al
    1H-MRS can monitor Metabolites changes of lateral intraventricular BDNF infusion into a Mouse Model of Alzheimer's disease in vivo.
    Neuroscience. 2013 Apr 19. pii: S0306-4522(13)00333.
    PubMed     Text format     Abstract available


  37. HANNULA MJ , Myohanen TT, Tenorio-Laranga J, Mannisto PT, et al
    Prolyl oligopeptidase colocalizes with alpha-synuclein, beta-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinson's and Alzheimer's diseases.
    Neuroscience. 2013 Apr 2. pii: S0306-4522(13)00304.
    PubMed     Text format     Abstract available


    February 2013
  38. KAMAT PK , Rai S, Swarnkar S, Shukla R, et al
    Okadaic acid induced Tau phosphorylation in rat brain: Role of NMDA receptor.
    Neuroscience. 2013 Feb 13. pii: S0306-4522(13)00122.
    PubMed     Text format     Abstract available


    December 2012
  39. ALGARZAE N , Hebron M, Miessau M, Moussa CE, et al
    Parkin prevents cortical atrophy and Abeta-induced alterations of brain metabolism: (1)(3)C NMR and magnetic resonance imaging studies in AD models.
    Neuroscience. 2012;225:22-34.
    PubMed     Text format     Abstract available


    October 2012
  40. DUFFY A , Holscher C
    The incretin analogue D-Ala(2)GIP reduces plaque load, astrogliosis and oxidative stress in an APP/PS1 mouse model of Alzheimer's disease.
    Neuroscience. 2012 Oct 25. pii: S0306-4522(12)01060.
    PubMed     Text format     Abstract available


  41. HAFEZ DM , Huang JY, Richardson JC, Masliah E, et al
    F-spondin gene transfer improves memory performance and reduces amyloid-beta levels in mice.
    Neuroscience. 2012;223:465-72.
    PubMed     Text format     Abstract available


    September 2012
  42. RAHIGUDE A , Bhutada P, Kaulaskar S, Aswar M, et al
    Participation of antioxidant and cholinergic system in protective effect of Naringenin against type-2 diabetes induced memory dysfunction in rats.
    Neuroscience. 2012 Sep 19. pii: S0306-4522(12)00934.
    PubMed     Text format     Abstract available


    August 2012
  43. LOU G , Zhang Q, Xiao F, Xiang Q, et al
    Intranasal administration of TAT-haFGF14-154 attenuates disease progression in a mouse model of Alzheimer's disease.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


    July 2012
  44. CAI Y , Xue ZQ, Zhang XM, Li MB, et al
    An age-related axon terminal pathology around the first olfactory relay that involves amyloidogenic protein overexpression without plaque formation.
    Neuroscience. 2012;215:160-73.
    PubMed     Text format     Abstract available


  45. BISIO A , Casteran M, Ballay Y, Manckoundia P, et al
    Motor resonance mechanisms are preserved in Alzheimer's disease patients.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


    June 2012
  46. FURUYA TK , Silva PN, Payao SL, Bertolucci PH, et al
    Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer's Disease patients.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


  47. MARQUES SC , Lemos R, Ferreiro E, Martins M, et al
    Epigenetic regulation of BACE1 in Alzheimer's disease patients and in transgenic mice.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


  48. ZHANG X , Wang J, Xing Y, Gong L, et al
    Effects of Ginsenoside Rg1 or 17beta-estradiol on a Cognitively Impaired, Ovariectomized Rat model of Alzheimer's Disease.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


  49. POZUETA J , Lefort R, Shelanski M
    Synaptic Changes in Alzheimer's Disease and its Models.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


    May 2012
  50. DAFNIS I , Tzinia AK, Tsilibary EC, Zannis VI, et al
    An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines.
    Neuroscience. 2012;210:21-32.
    PubMed     Text format     Abstract available


  51. CUI W , Sun Y, Wang Z, Xu C, et al
    Liver X receptor activation attenuates inflammatory response and protects cholinergic neurons in APP/PS1 transgenic mice.
    Neuroscience. 2012;210:200-10.
    PubMed     Text format     Abstract available


    April 2012
  52. KAWAHARA K , Suenobu M, Yoshida A, Koga K, et al
    Intracerebral microinjection of interleukin-4/interleukin-13 reduces beta-amyloid accumulation in the ipsilateral side and improves cognitive deficits in young amyloid precursor protein 23 mice.
    Neuroscience. 2012;207:243-60.
    PubMed     Text format     Abstract available


    March 2012
  53. JAVED H , Khan MM, Ahmad A, Vaibhav K, et al
    Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


    February 2012
  54. WONG J , Higgins M, Halliday G, Garner B, et al
    Amyloid beta selectively modulates neuronal TrkB alternative transcript expression with implications for Alzheimer's disease.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


    January 2012
  55. SNIGDHA S , Astarita G, Piomelli D, Cotman CW, et al
    Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain.
    Neuroscience. 2012;202:326-33.
    PubMed     Text format     Abstract available


  56. TAKUMA K , Mizoguchi H, Funatsu Y, Hoshina Y, et al
    Combination of chronic stress and ovariectomy causes conditioned fear memory deficits and hippocampal cholinergic neuronal loss in mice.
    Neuroscience. 2012.
    PubMed     Text format     Abstract available


    December 2011
  57. JOLIVALT CG , Calcutt NA, Masliah E
    Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease.
    Neuroscience. 2011.
    PubMed     Text format     Abstract available


  58. DE OLIVEIRA J , Hort MA, Moreira EL, Glaser V, et al
    Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress.
    Neuroscience. 2011;197:99-106.
    PubMed     Text format     Abstract available


    October 2011
  59. YUKI D , Sugiura Y, Zaima N, Akatsu H, et al
    Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex.
    Neuroscience. 2011;193:44-53.
    PubMed     Text format     Abstract available


    September 2011
  60. BICCA MA , Figueiredo CP, Piermartiri TC, Meotti FC, et al
    The selective and competitive N-methyl-D-aspartate receptor antagonist, (-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid, prevents synaptic toxicity induced by amyloid-beta in mice.
    Neuroscience. 2011;192:631-41.
    PubMed     Text format     Abstract available


  61. KURATA T , Miyazaki K, Kozuki M, Morimoto N, et al
    Progressive neurovascular disturbances in the cerebral cortex of Alzheimer's disease-model mice: protection by atorvastatin and pitavastatin.
    Neuroscience. 2011.
    PubMed     Text format     Abstract available


  62. PERI A , Benvenuti S, Luciani P, Deledda C, et al
    Membrane cholesterol as a mediator of the neuroprotective effects of estrogens.
    Neuroscience. 2011;191:107-17.
    PubMed     Text format     Abstract available


    August 2011
  63. ZAHEER S , Thangavel R, Sahu SK, Zaheer A, et al
    Augmented expression of glia maturation factor in Alzheimer's disease.
    Neuroscience. 2011.
    PubMed     Text format     Abstract available


    July 2011
  64. ZILKA N , Zilkova M, Kazmerova Z, Sarissky M, et al
    Mesenchymal stem cells rescue the Alzheimer's disease cell model from cell death induced by misfolded truncated tau.
    Neuroscience. 2011.
    PubMed     Text format     Abstract available


  65. SAIN H , Sharma B, Jaggi AS, Singh N, et al
    Pharmacological investigations on potential of peroxisome proliferator-activated receptor-gamma agonists in hyperhomocysteinemia-induced vascular dementia in rats.
    Neuroscience. 2011.
    PubMed     Text format     Abstract available


    April 2011
  66. FUJIWARA H , Takayama S, Iwasaki K, Tabuchi M, et al
    Yokukansan, a traditional Japanese medicine, ameliorates memory disturbance and abnormal social interaction with anti-aggregation effect of cerebral amyloid beta proteins in amyloid precursor protein transgenic mice.
    Neuroscience. 2011;180:305-13.
    PubMed     Text format     Abstract available


  67. LUCHETTI S , Huitinga I, Swaab DF
    Neurosteroid and GABA-A receptor alterations in Alzheimer's disease, Parkinson's disease and multiple sclerosis.
    Neuroscience. 2011.
    PubMed     Text format    


  68. DRAGICEVIC N , Bradshaw PC, Mamcarz M, Lin X, et al
    Long-term electromagnetic field treatment enhances brain mitochondrial function of both Alzheimer's transgenic mice and normal mice: a mechanism for electromagnetic field-induced cognitive benefit?
    Neuroscience. 2011.
    PubMed     Text format    


  69. YANAGISAWA D , Amatsubo T, Morikawa S, Taguchi H, et al
    In vivo detection of amyloid beta deposition using (19)F magnetic resonance imaging with a (19)F-containing curcumin derivative in a mouse model of Alzheimer's disease.
    Neuroscience. 2011.
    PubMed     Text format     Abstract available


    March 2011
  70. MAESAKO M , Uemura K, Kubota M, Hiyoshi K, et al
    Effect of glycogen synthase kinase 3 beta-mediated presenilin 1 phosphorylation on amyloid beta production is negatively regulated by insulin receptor cleavage.
    Neuroscience. 2011;177:298-307.
    PubMed     Text format     Abstract available


  71. JARDANHAZI-KURUTZ D , Kummer MP, Terwel D, Vogel K, et al
    Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice.
    Neuroscience. 2011;176:396-407.
    PubMed     Text format     Abstract available


    January 2011
  72. WANG P , Jiang S, Cui Y, Yue Z, et al
    The n-terminal 5-MER peptide analogue P165 of amyloid precursor protein exerts protective effects on SH-SY5Y cells and rat hippocampus neuronal synapses.
    Neuroscience. 2011;173:169-78.
    PubMed     Text format     Abstract available


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