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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Alzheimer's Disease

Free Subscription Articles published in J Neurochem Retrieve available abstracts of 69 articles: HTML format

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May 2008
1. GUSTAW KA , Garrett MR, Lee HG, Castellani RJ, et al
   Antigen-Antibody Dissociation in Alzheimer Disease: A Novel Approach to Diagnosis.
   J Neurochem. 2008;.
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2. MALIK B , Currais A, Soriano S
   Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta(1-42) exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
   J Neurochem. 2008;.
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3. PASINETTI GM , Eberstein JA
   METABOLIC SYNDROME AND THE ROLE OF DIETARY LIFESTYLES IN ALZHEIMER'S DISEASE.
   J Neurochem. 2008;.
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4. MINKEVICIENE R , Ihalainen J, Malm T, Matilainen O, et al
   Age-related decrease in stimulated glutamate release and vesicular glutamate transporters in APP/PS1 transgenic and wild-type mice.
   J Neurochem. 2008;105:584-94.
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   March 2008
5. TOUGU V , Karafin A, Palumaa P
   Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide.
   J Neurochem. 2008;104:1249-59.
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6. TACHIDA Y , Nakagawa K, Saito T, Saido TC, et al
   Interleukin-1 beta up-regulates TACE to enhance alpha-cleavage of APP in neurons: resulting decrease in Abeta production.
   J Neurochem. 2008;104:1387-93.
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   January 2008
7. MAEZAWA I , Hong HS, Liu R, Wu CY, et al
   Congo red and thioflavin-T analogs detect Abeta oligomers.
   J Neurochem. 2008;104:457-68.
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   December 2007
8. HOOPER C , Killick R, Lovestone S
   The GSK3 hypothesis of Alzheimer's disease.
   J Neurochem. 2007;.
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9. ITO S , Ohtsuki S, Kamiie J, Nezu Y, et al
   Cerebral clearance of human amyloid-beta peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes.
   J Neurochem. 2007;103:2482-90.
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   November 2007
10. LOPEZ JR , Lyckman A, Oddo S, Laferla FM, et al
    Increased intraneuronal resting [Ca(2+)] in adult Alzheimer's disease mice.
    J Neurochem. 2007;.
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11. RYOO SR , Cho HJ, Lee HW, Jeong HK, et al
    Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
    J Neurochem. 2007;.
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12. KARLSTROM H , Brooks WS, Kwok JB, Broe GA, et al
    Variable phenotype of Alzheimer's disease with spastic paraparesis.
    J Neurochem. 2007;.
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13. NGUYEN TV , Galvan V, Huang W, Banwait S, et al
    Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.
    J Neurochem. 2007;.
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14. CACQUEVEL M , Aeschbach L, Osenkowski P, Li D, et al
    Rapid purification of active gamma-secretase, an intramembrane protease implicated in Alzheimer's disease.
    J Neurochem. 2007;.
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15. LICHTLEN P , Mohajeri MH
    Antibody-based approaches in Alzheimer's research: safety, pharmacokinetics, metabolism, and analytical tools.
    J Neurochem. 2007;.
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16. HAN X
    Potential mechanisms contributing to sulfatide depletion at the earliest clinically recognizable stage of Alzheimer's disease: a tale of shotgun lipidomics.
    J Neurochem. 2007;103 Suppl 1:171-9.
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17. HARTMANN T , Kuchenbecker J, Grimm MO
    Alzheimer's disease: the lipid connection.
    J Neurochem. 2007;103 Suppl 1:159-70.
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18. LEVI O , Dolev I, Belinson H, Michaelson DM, et al
    Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation.
    J Neurochem. 2007;103:1031-40.
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    October 2007
19. LIANG Z , Liu F, Grundke-Iqbal I, Iqbal K, et al
    Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain.
    J Neurochem. 2007;.
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20. ENGLUND H , Sehlin D, Johansson AS, Nilsson LN, et al
    Sensitive ELISA detection of amyloid-beta protofibrils in biological samples.
    J Neurochem. 2007;103:334-45.
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21. BIBL M , Esselmann H, Mollenhauer B, Weniger G, et al
    Blood-based neurochemical diagnosis of vascular dementia: a pilot study.
    J Neurochem. 2007;103:467-74.
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    September 2007
22. MALONEY B , Ge YW, Alley GM, Lahiri DK, et al
    Important differences between human and mouse APOE gene promoters: limitation of mouse APOE model in studying Alzheimer's disease.
    J Neurochem. 2007;.
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23. SENECHAL Y , Kelly PH, Cryan JF, Natt F, et al
    Amyloid precursor protein knockdown by siRNA impairs spontaneous alternation in adult mice.
    J Neurochem. 2007;102:1928-40.
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    August 2007
24. MA QL , Harris-White ME, Ubeda OJ, Simmons M, et al
    Evidence of Abeta- and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models.
    J Neurochem. 2007;.
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25. CONRAD C , Zhu J, Conrad C, Schoenfeld D, et al
    Single molecule profiling of tau gene expression in Alzheimer's disease.
    J Neurochem. 2007;.
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26. RISSMAN RA , De Blas AL, Armstrong DM
    GABA(A) receptors in aging and Alzheimer's disease.
    J Neurochem. 2007;.
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27. COLE AR , Noble W, Aalten LV, Plattner F, et al
    Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.
    J Neurochem. 2007;.
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28. GANDY S , Zhang YW, Ikin A, Schmidt SD, et al
    Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo.
    J Neurochem. 2007;102:619-26.
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29. ODDO S , Caccamo A, Cheng D, Jouleh B, et al
    Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice.
    J Neurochem. 2007;102:1053-63.
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30. CHAN A , Shea TB
    Folate deprivation increases presenilin expression, gamma-secretase activity, and Abeta levels in murine brain: potentiation by ApoE deficiency and alleviation by dietary S-adenosyl methionine.
    J Neurochem. 2007;102:753-60.
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31. DEHVARI N , Cedazo-Minguez A, Isacsson O, Nilsson T, et al
    Presenilin dependence of phospholipase C and protein kinase C signaling.
    J Neurochem. 2007;102:848-57.
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    July 2007
32. PODUSLO JF , Ramakrishnan M, Holasek SS, Ramirez-Alvarado M, et al
    In vivo targeting of antibody fragments to the nervous system for Alzheimer's disease immunotherapy and molecular imaging of amyloid plaques.
    J Neurochem. 2007;102:420-33.
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33. HEO C , Chang KA, Choi HS, Kim HS, et al
    Effects of the monomeric, oligomeric, and fibrillar Abeta42 peptides on the proliferation and differentiation of adult neural stem cells from subventricular zone.
    J Neurochem. 2007;102:493-500.
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    June 2007
34. VAYA J , Schipper HM
    Oxysterols, cholesterol homeostasis, and Alzheimer disease.
    J Neurochem. 2007;.
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35. WALSH DM , Selkoe DJ
    A beta oligomers - a decade of discovery.
    J Neurochem. 2007;101:1172-84.
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    May 2007
36. SAHLIN C , Lord A, Magnusson K, Englund H, et al
    The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase.
    J Neurochem. 2007;101:854-62.
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37. WILTFANG J , Esselmann H, Bibl M, Hull M, et al
    Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load.
    J Neurochem. 2007;101:1053-9.
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    April 2007
38. EHRET A , Birthelmer A, Rutz S, Riegert C, et al
    Agonist-mediated regulation of presynaptic receptor function during development of rat septal neurons in culture.
    J Neurochem. 2007;.
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39. GARCIA-ALLOZA M , Borrelli LA, Rozkalne A, Hyman BT, et al
    Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.
    J Neurochem. 2007;.
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40. RAO HV , Thirumangalakudi L, Desmond P, Grammas P, et al
    Cyclin D1, cdk4, and Bim are involved in thrombin-induced apoptosis in cultured cortical neurons.
    J Neurochem. 2007;101:498-505.
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    March 2007
41. GINESTET L , Ferrario JE, Raisman-Vozari R, Hirsch EC, et al
    Donepezil induces a cholinergic sprouting in basocortical degeneration.
    J Neurochem. 2007;.
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42. LIN P , Li F, Zhang YW, Huang H, et al
    Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis.
    J Neurochem. 2007;100:1505-14.
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    February 2007
43. GARCIA-AYLLON MS , Silveyra MX, Andreasen N, Brimijoin S, et al
    Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease.
    J Neurochem. 2007;.
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44. GILLARDON F , Kloss A, Berg M, Neumann M, et al
    The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity.
    J Neurochem. 2007;.
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45. SMALL DH , Maksel D, Kerr ML, Ng J, et al
    The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor.
    J Neurochem. 2007;.
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46. HUSSAIN I , Hawkins J, Harrison D, Hille C, et al
    Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    J Neurochem. 2007;100:802-9.
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    January 2007
47. SPIRES TL , Hannan AJ
    Molecular mechanisms mediating pathological plasticity in Huntington's disease and Alzheimer's disease.
    J Neurochem. 2007;.
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48. LAMBERT MP , Velasco PT, Chang L, Viola KL, et al
    Monoclonal antibodies that target pathological assemblies of Abeta.
    J Neurochem. 2007;100:23-35.
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    December 2006
49. CHEN K , Maley J, Yu PH
    Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis.
    J Neurochem. 2006;99:1413-24.
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    November 2006
50. AVRAMOVICH-TIROSH Y , Amit T, Bar-Am O, Zheng H, et al
    Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhbitor drug, M-30, for the treatment of Alzheimer's disease.
    J Neurochem. 2006;.
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51. SMALL DH , Cappai R
    Alois Alzheimer and Alzheimer's disease: a centennial perspective.
    J Neurochem. 2006;99:708-10.
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52. GOLDE TE
    Disease modifying therapy for AD?
    J Neurochem. 2006;99:689-707.
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53. CHEN Q , Wang S, Thompson SN, Hall ED, et al
    Identification and characterization of PEBP as a calpain substrate.
    J Neurochem. 2006;99:1133-41.
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    October 2006
54. MEI M , Su B, Harrison K, Chao M, et al
    Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease.
    J Neurochem. 2006;.
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55. GHRIBI O , Golovko MY, Larsen B, Schrag M, et al
    Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets.
    J Neurochem. 2006;99:438-49.
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    September 2006
56. RAMALHO RM , Borralho PM, Castro RE, Sola S, et al
    Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.
    J Neurochem. 2006;98:1610-8.
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57. JOZWIAK K , Zekanowski C, Filipek S
    Linear patterns of Alzheimer's disease mutations along alpha-helices of presenilins as a tool for PS-1 model construction.
    J Neurochem. 2006;98:1560-72.
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58. BUTTERFIELD DA , Abdul HM, Opii W, Newman SF, et al
    Pin1 in Alzheimer's disease.
    J Neurochem. 2006;98:1697-706.
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59. FU H , Li W, Lao Y, Luo J, et al
    Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels.
    J Neurochem. 2006;98:1400-10.
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    August 2006
60. KIRVELL SL , Esiri M, Francis PT
    Down-regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease.
    J Neurochem. 2006;98:939-50.
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61. COULSON EJ
    Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?
    J Neurochem. 2006;98:654-60.
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    July 2006
62. SIEGEL DA , Davies P, Dobrenis K, Huang M, et al
    Tomoregulin-2 is found extensively in plaques in Alzheimer's disease brain.
    J Neurochem. 2006;98:34-44.
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    June 2006
63. GOTZ J , Ittner LM, Kins S
    Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?
    J Neurochem. 2006;.
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64. MASTERS CL , Cappai R, Barnham KJ, Villemagne VL, et al
    Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics.
    J Neurochem. 2006;97:1700-25.
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    May 2006
65. GUILLOZET-BONGAARTS AL , Cahill ME, Cryns VL, Reynolds MR, et al
    Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.
    J Neurochem. 2006;97:1005-14.
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66. PARDOSSI-PIQUARD R , Dunys J, Yu G, St George-Hyslop P, et al
    Neprilysin activity and expression are controlled by nicastrin.
    J Neurochem. 2006;97:1052-6.
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    April 2006
67. CHEN CD , Oh SY, Hinman JD, Abraham CR, et al
    Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation.
    J Neurochem. 2006;97:30-43.
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68. MORIGUCHI S , Han F, Nakagawasai O, Tadano T, et al
    Decreased calcium/calmodulin-dependent protein kinase II and protein kinase C activities mediate impairment of hippocampal long-term potentiation in the olfactory bulbectomized mice.
    J Neurochem. 2006;97:22-9.
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    March 2006
69. NOWAK K , Lange-Dohna C, Zeitschel U, Gunther A, et al
    The transcription factor Yin Yang 1 is an activator of BACE1 expression.
    J Neurochem. 2006;96:1696-707.
    PubMed     Related articles    Abstract available
    
    

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