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Alzheimer's Disease

Free Subscription Articles published in J Neurochem Retrieve available abstracts of 86 articles: HTML format Text format

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April 2012
1. PARPURA V , Heneka MT, Montana V, Oliet SH, et al
   Glial cells in (patho)physiology.
   J Neurochem. 2012;121:4-27.
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   March 2012
2. ZAHID S , Oellerich M, Asif AR, Ahmed N, et al
   Phosphoproteome profiling of substantia nigra and cortex regions of Alzheimer's disease patients.
   J Neurochem. 2012 Mar 21. doi: 10.1111/j.1471-4159.2012.07737.
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3. ZETTERBERG H , Hammarstrom P
   Power tools for Alzheimer's disease - an electrochemical preamp for Abeta
   J Neurochem. 2012 Mar 12. doi: 10.1111/j.1471-4159.2012.07730.
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4. DENG J , Hou H, Giunta B, Mori T, et al
   Autoreactive-Abeta antibodies promote APP beta-secretase processing.
   J Neurochem. 2012;120:732-40.
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   February 2012
5. PRABHULKAR S , Piatyszek R, Cirrito JR, Wu ZZ, et al
   Microbiosensor for Alzheimer's Disease Diagnostics: Detection of Amyloid Beta Biomarkers.
   J Neurochem. 2012 Feb 28. doi: 10.1111/j.1471-4159.2012.07709.
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6. CAPIRALLA H , Vingtdeux V, Zhao H, Sankowski R, et al
   Resveratrol mitigates lipopolysaccharide- and Abeta-mediated microglial inflammation by inhibiting the TLR4/NF-kappaB/STAT signaling cascade.
   J Neurochem. 2012;120:461-72.
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7. SWERDLOW RH
   beta-Apptists and Tauists, it is time for a sermon from the book of biogenesis.
   J Neurochem. 2012;120:347-9.
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   January 2012
8. CHOI SH , Aid S, Kim HW, Jackson SH, et al
   Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.
   J Neurochem. 2012;120:292-301.
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9. SLEMMON JR , Meredith J, Guss V, Andreasson U, et al
   Measurement of Abeta1-42 in cerebrospinal fluid is influenced by matrix effects.
   J Neurochem. 2012;120:325-33.
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10. SCHNEIDER A , Simons M
    Antioxidative strategies in cognitive impairment: a novel connection between biliverdin-reductase and statins.
    J Neurochem. 2012;120:1-3.
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11. SMITH GC
    Farewell, 'renegade researcher': your voice will be missed.
    J Neurochem. 2012;120 Suppl 1:1-2.
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12. CHASSEIGNEAUX S , Allinquant B
    Functions of Abeta, sAPPalpha and sAPPbeta : similarities and differences.
    J Neurochem. 2012;120 Suppl 1:99-108.
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13. PARDOSSI-PIQUARD R , Checler F
    The physiology of the beta-amyloid precursor protein intracellular domain AICD.
    J Neurochem. 2012;120 Suppl 1:109-24.
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14. KANDALEPAS PC , Vassar R
    Identification and biology of beta-secretase.
    J Neurochem. 2012;120 Suppl 1:55-61.
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15. ST GEORGE-HYSLOP P , Fraser PE
    Assembly of the presenilin gamma-/epsilon-secretase complex.
    J Neurochem. 2012;120 Suppl 1:84-8.
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16. LARSON ME , Lesne SE
    Soluble Abeta oligomer production and toxicity.
    J Neurochem. 2012;120 Suppl 1:125-39.
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17. VINGTDEUX V , Marambaud P
    Identification and biology of alpha-secretase.
    J Neurochem. 2012;120 Suppl 1:34-45.
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18. POSTINA R
    Activation of alpha-secretase cleavage.
    J Neurochem. 2012;120 Suppl 1:46-54.
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    December 2011
19. CHOI DY , Lee JW, Lin G, Lee YJ, et al
    Obovatol improves cognitive functions in animal models for Alzheimer's disease.
    J Neurochem. 2011 Dec 30. doi: 10.1111/j.1471-4159.2011.07642.
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20. CHECLER F , Turner AJ
    Journal of Neurochemistry special issue on Alzheimer's disease: 'amyloid cascade hypothesis - 20 years on'
    J Neurochem. 2011 Dec 19. doi: 10.1111/j.1471-4159.2011.07603.
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21. TAN J , Evin G
    BACE1 Trafficking and Alzheimer's Disease Pathogenesis.
    J Neurochem. 2011 Dec 15. doi: 10.1111/j.1471-4159.2011.07623.
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22. DOMINGUES SC , Henriques AG, Fardilha M, da Cruz E Silva EF, et al
    Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform.
    J Neurochem. 2011;119:1086-98.
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    November 2011
23. GHOSH AK , Brindisi M, Tang J
    Developing beta-secretase inhibitors for treatment of Alzheimer's disease.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07476.
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24. GOATE A , Hardy J
    Twenty years of Alzheimer's disease-causing mutations.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07575.
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25. ZHANG H , Ma Q, Zhang YW, Xu H, et al
    Proteolytic processing of Alzheimer's beta-amyloid precursor protein.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07519.
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26. SUN X , Bromley-Brits K, Song W
    Regulation of beta-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer's Disease.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07515.
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27. NALIVAEVA NN , Beckett C, Belyaev ND, Turner AJ, et al
    Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07510.
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28. FISHER A
    Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer's disease.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07507.
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29. MA T , Klann E
    Amyloid beta: linking synaptic plasticity failure to memory disruption in Alzheimer's disease.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07506.
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30. WOLFE MS
    gamma-Secretase inhibitors and modulators for Alzheimer's disease.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07501.
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31. ROBERTS BR , Ryan TM, Bush AI, Masters CL, et al
    The role of metallobiology and amyloid-beta peptides in Alzheimer's disease.
    J Neurochem. 2011 Nov 28. doi: 10.1111/j.1471-4159.2011.07500.
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32. SHENG B , Wang X, Su B, Lee HG, et al
    Impaired Mitochondrial Biogenesis Contributes to Mitochondrial Dysfunction in Alzheimer's Disease.
    J Neurochem. 2011 Nov 11. doi: 10.1111/j.1471-4159.2011.07581.
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33. PRADO MA , Baron G
    Seeding plaques in Alzheimer's disease.
    J Neurochem. 2011 Nov 3. doi: 10.1111/j.1471-4159.2011.07574.
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34. TESCO G
    Autophagy: a common road to perdition in acute brain injuries and Alzheimer's disease.
    J Neurochem. 2011 Nov 3. doi: 10.1111/j.1471-4159.2011.07573.
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35. HOSHINO T , Namba T, Takehara M, Murao N, et al
    Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor.
    J Neurochem. 2011 Nov 1. doi: 10.1111/j.1471-4159.2011.07567.
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    October 2011
36. LIU G , Jiang Y, Wang P, Feng R, et al
    Cell adhesion molecules contribute to Alzheimer's disease: multiple pathway analyses of two genome-wide association studies.
    J Neurochem. 2011 Oct 21. doi: 10.1111/j.1471-4159.2011.07547.
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37. BARONE E , Mancuso C, Di Domenico F, Sultana R, et al
    Biliverdin Reductase-A: a Novel Drug Target for Atorvastatin in a Dog Preclinical Model of Alzheimer Disease.
    J Neurochem. 2011 Oct 17. doi: 10.1111/j.1471-4159.2011.07538.
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38. LEE ST , Chu K, Park JE, Jung KH, et al
    Erythropoietin improves memory function with reducing endothelial dysfunction and amyloid-beta burden in Alzheimer's disease models.
    J Neurochem. 2011 Oct 17. doi: 10.1111/j.1471-4159.2011.07534.
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39. ONISHI T , Iwashita H, Uno Y, Kunitomo J, et al
    A Novel Glycogen Synthase Kinase-3 Inhibitor 2-methyl-5-(3-{4-[(S)-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole (MMBO) Decreases Tau Phosphorylation and Ameliorates Cognitive Deficits in a Transgenic Model of Alzheimer's Disease.
    J Neurochem. 2011 Oct 12. doi: 10.1111/j.1471-4159.2011.07532.
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40. JEONG YH , Kim JM, Yoo J, Lee SH, et al
    Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model.
    J Neurochem. 2011 Oct 3. doi: 10.1111/j.1471-4159.2011.07514.
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41. O'NUALLAIN B , Klyubin I, Mc Donald JM, Foster JS, et al
    A monoclonal antibody against synthetic Abeta dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting Abeta.
    J Neurochem. 2011;119:189-201.
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    September 2011
42. LY PT , Song W
    Loss of activated CaMKII at the synapse underlies Alzheimer's disease memory loss.
    J Neurochem. 2011 Sep 7. doi: 10.1111/j.1471-4159.2011.07473.
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43. SUN KH , Chang KH, Clawson S, Ghosh S, et al
    Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity.
    J Neurochem. 2011;118:902-14.
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    August 2011
44. DELRIEU J , Ousset PJ, Caillaud C, Vellas B, et al
    "Clinical trials in Alzheimer's disease": immunotherapy approaches.
    J Neurochem. 2011 Aug 30. doi: 10.1111/j.1471-4159.2011.07458.
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45. REESE LC , Laezza F, Woltjer R, Taglialatela G, et al
    Dysregulated phosphorylation of Ca(2+) /calmodulin-dependent protein kinase II-alpha in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease.
    J Neurochem. 2011 Aug 26. doi: 10.1111/j.1471-4159.2011.07447.
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46. TRAN TT , Srivareerat M, Alhaider IA, Alkadhi KA, et al
    Chronic psychosocial stress enhances long-term depression in a subthreshold amyloid-beta rat model of Alzheimer's disease.
    J Neurochem. 2011 Aug 19. doi: 10.1111/j.1471-4159.2011.07437.
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47. CHEUNG ZH , Ip NY
    Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives.
    J Neurochem. 2011;118:317-25.
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    July 2011
48. CROUCH PJ , Savva MS, Hung LW, Donnelly PS, et al
    The Alzheimer's therapeutic PBT2 promotes amyloid-beta degradation and GSK3 phosphorylation via a metal chaperone activity.
    J Neurochem. 2011 Jul 28. doi: 10.1111/j.1471-4159.2011.07402.
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    June 2011
49. FABBRO S , Schaller K, Seeds NW
    Abeta Levels are Significantly Reduced and Spatial Memory Defects are Rescued in a Novel Neuroserpin-Deficient Alzheimer's Disease Transgenic Mouse Model.
    J Neurochem. 2011 Jun 20. doi: 10.1111/j.1471-4159.2011.07359.
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    May 2011
50. SALMINEN A , Kaarniranta K, Haapasalo A, Soininen H, et al
    AMP-activated protein kinase (AMPK): a potential player in Alzheimer's disease.
    J Neurochem. 2011 May 30. doi: 10.1111/j.1471-4159.2011.07331.
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51. SATO K , Minegishi S, Takano J, Plattner F, et al
    Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25.
    J Neurochem. 2011;117:504-15.
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52. SAMBAMURTI K , Greig NH, Utsuki T, Barnwell EL, et al
    Targets for AD treatment: conflicting messages from gamma-secretase inhibitors.
    J Neurochem. 2011;117:359-74.
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53. RAY B , Chauhan NB, Lahiri DK
    Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model.
    J Neurochem. 2011;117:388-402.
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    April 2011
54. CHEN LM , Xiong YS, Kong FL, Qu M, et al
    Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.
    J Neurochem. 2011 Apr 18. doi: 10.1111/j.1471-4159.2011.07275.
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    March 2011
55. SANTOS RX , Correia SC, Cardoso S, Carvalho C, et al
    Effects of rapamycin and TOR on aging and memory: Implications for Alzheimer's disease.
    J Neurochem. 2011 Mar 29. doi: 10.1111/j.1471-4159.2011.07262.
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56. RISSMAN RA , Mobley WC
    Implications for treatment: GABA(A) receptors in aging, Down Syndrome and Alzheimer's Disease.
    J Neurochem. 2011 Mar 9. doi: 10.1111/j.1471-4159.2011.07237.
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    February 2011
57. SHRUSTER A , Eldar-Finkelman H, Melamed E, Offen D, et al
    Wnt signaling pathway overcomes the disruption of neuronal differentiation of neural progenitor cells induced by oligomeric amyloid beta-peptide.
    J Neurochem. 2011;116:522-9.
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    January 2011
58. ONO K , Yamada M
    Low-n oligomers as therapeutic targets of Alzheimer's disease.
    J Neurochem. 2011 Jan 18. doi: 10.1111/j.1471-4159.2011.07187.
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59. GRIMM MO , Kuchenbecker J, Rothhaar TL, Grosgen S, et al
    Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease.
    J Neurochem. 2011 Jan 7. doi: 10.1111/j.1471-4159.2010.07070.
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60. LEE JC , Simonyi A, Sun AY, Sun GY, et al
    Phospholipases A(2) and neural membrane dynamics: implications for Alzheimer's disease.
    J Neurochem. 2011 Jan 7. doi: 10.1111/j.1471-4159.2010.07033.
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61. YANAGISAWA K
    Pathological significance of ganglioside clusters in Alzheimer's disease.
    J Neurochem. 2011 Jan 7. doi: 10.1111/j.1471-4159.2010.07006.
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62. HERRERA JL , Diaz M, Hernandez-Fernaud JR, Salido E, et al
    Voltage-dependent anion channel as a resident protein of lipid rafts: post-transductional regulation by estrogens and involvement in neuronal preservation against Alzheimer's disease.
    J Neurochem. 2011 Jan 7. doi: 10.1111/j.1471-4159.2010.06987.
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63. SMITH P , Al Hashimi A, Girard J, Delay C, et al
    In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs.
    J Neurochem. 2011;116:240-7.
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    December 2010
64. SUTHERLAND GT , Janitz M, Kril JJ
    Understanding the pathogenesis of Alzheimer's disease: Will RNA-Seq realize the promise of transcriptomics?
    J Neurochem. 2010 Dec 22. doi: 10.1111/j.1471-4159.2010.07157.
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    November 2010
65. HAHN S , Bruning T, Ness J, Czirr E, et al
    Presenilin-1 (PSEN1) but not amyloid precursor protein (APP) mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to gamma-secretase modulators (GSMs) regardless of their potency and structure.
    J Neurochem. 2010 Nov 20. doi: 10.1111/j.1471-4159.2010.07118.
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66. MCCAMPBELL A , Wessner K, Marlatt MW, Wolffe C, et al
    Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine.
    J Neurochem. 2010 Nov 5. doi: 10.1111/j.1471-4159.2010.07087.
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67. SOUTAR MP , Kim WY, Williamson R, Peggie M, et al
    Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain.
    J Neurochem. 2010;115:974-83.
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68. BHAT NR
    Linking cardiometabolic disorders to sporadic Alzheimer's disease: a perspective on potential mechanisms and mediators.
    J Neurochem. 2010;115:551-62.
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    October 2010
69. LICHTENTHALER SF
    alpha-secretase in Alzheimer's disease: molecular identity, regulation and therapeutic potential.
    J Neurochem. 2010 Oct 29. doi: 10.1111/j.1471-4159.2010.07081.
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70. DECKER H , Jurgensen S, Adrover MF, Brito-Moreira J, et al
    N-methyl-D-aspartate receptors are required for synaptic targeting of Alzheimer's toxic Abeta oligomers.
    J Neurochem. 2010 Oct 15. doi: 10.1111/j.1471-4159.2010.07058.
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71. SCHETTINI G , Govoni S, Racchi M, Rodriguez G, et al
    PHOSPHORYLATION OF APP-CTF-AICD DOMAINS AND INTERACTION WITH ADAPTOR PROTEINS: SIGNAL TRANSDUCTION AND/OR TRANSCRIPTIONAL ROLE. RELEVANCE FOR ALZHEIMER PATHOLOGY.
    J Neurochem. 2010 Oct 8. doi: 10.1111/j.1471-4159.2010.07044.
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    September 2010
72. ZLOKOVIC BV , Deane R, Sagare AP, Bell RD, et al
    Low density lipoprotein receptor related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid beta-peptide elimination from the brain.
    J Neurochem. 2010 Sep 20. doi: 10.1111/j.1471-4159.2010.07002.
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    August 2010
73. HUGHES M , Snetkov V, Rose RS, Trousil S, et al
    Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP.
    J Neurochem. 2010;114:832-42.
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74. JUREUS A , Swahn BM, Sandell J, Jeppsson F, et al
    Characterization of AZD4694, a novel fluorinated Abeta plaque neuroimaging PET radioligand.
    J Neurochem. 2010;114:784-94.
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    July 2010
75. WANG S , Wang R, Chen L, Bennett DA, et al
    Expression and functional profiling of neprilysin, insulin degrading enzyme and endothelin converting enzyme in prospectively studied elderly and Alzheimer's brain.
    J Neurochem. 2010.
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76. SEO H , Isacson O
    The hAPP-YAC transgenic model has elevated UPS activity in the frontal cortex similar to Alzheimer's disease and Down's syndrome.
    J Neurochem. 2010.
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77. SHEN S , Callaghan D, Juzwik C, Xiong H, et al
    ABCG2 reduces ROS-mediated toxicity and inflammation: A potential role in Alzheimer's disease.
    J Neurochem. 2010.
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78. ZHENG Z , White C, Lee J, Peterson TS, et al
    ALTERED MICROGLIAL COPPER HOMEOSTASIS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE.
    J Neurochem. 2010.
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79. BUCHANAN MM , Hutchinson M, Watkins LR, Yin H, et al
    Toll-like receptor 4 in CNS pathologies.
    J Neurochem. 2010;114:13-27.
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    June 2010
80. ONYANGO IG , Ahn JY, Tuttle JB, Bennett JP Jr, et al
    Nerve growth factor attenuates oxidant-induced beta-amyloid neurotoxicity in sporadic Alzheimer's disease cybrids.
    J Neurochem. 2010.
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    May 2010
81. GALINDO MF , Ikuta I, Zhu X, Casadesus G, et al
    Mitochondrial biology in Alzheimer's disease pathogenesis.
    J Neurochem. 2010.
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82. AJMO JM , Bailey LA, Howell MD, Cortez LK, et al
    Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw.
    J Neurochem. 2010;113:784-95.
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    April 2010
83. RYU YS , Park SY, Jung MS, Yoon SH, et al
    Dyrk1A-mediated phosphorylation of Presenilin 1: a functional link between Down syndrome and Alzheimer's disease.
    J Neurochem. 2010.
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    March 2010
84. HENRIQUES AG , Vieira SI, da Cruz E Silva EF, da Cruz E Silva OA, et al
    Abeta promotes Alzheimer's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons.
    J Neurochem. 2010.
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85. CHANG KH , de Pablo Y, Lee HP, Lee HG, et al
    Cdk5 is a Major Regulator of p38 Cascade: Relevance to Neurotoxicity in Alzheimer's Disease.
    J Neurochem. 2010.
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86. YANG T , Arslanova D, Xu X, Li YM, et al
    In Vivo Manifestation of Notch Related Phenotypes in Zebrafish Treated with Alzheimer's Amyloid Reducing gamma-Secretase Inhibitors.
    J Neurochem. 2010.
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