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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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  Alzheimer's Disease

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Articles published in Am J Pathol

Retrieve available abstracts of 20 articles:
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Single Articles


    July 2008
  1. WANG X , Su B, Fujioka H, Zhu X, et al
    Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients.
    Am J Pathol. 2008;.
    PubMed     Related articles    Abstract available


    June 2008
  2. CATALDO AM , Mathews PM, Boiteau AB, Hassinger LC, et al
    Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology. Accelerated Endocytosis Promotes Late Endocytic Defects.
    Am J Pathol. 2008;.
    PubMed     Related articles    Abstract available


    May 2008
  3. FEIN JA , Sokolow S, Miller CA, Vinters HV, et al
    Co-Localization of Amyloid Beta and Tau Pathology in Alzheimer's Disease Synaptosomes.
    Am J Pathol. 2008;.
    PubMed     Related articles    Abstract available


    April 2008
  4. EL-AMOURI SS , Zhu H, Yu J, Marr R, et al
    Neprilysin: An Enzyme Candidate to Slow the Progression of Alzheimer's Disease.
    Am J Pathol. 2008;.
    PubMed     Related articles    Abstract available


    March 2008
  5. TERWEL D , Muyllaert D, Dewachter I, Borghgraef P, et al
    Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice.
    Am J Pathol. 2008;172:786-98.
    PubMed     Related articles    Abstract available


    December 2007
  6. BOLMONT T , Clavaguera F, Meyer-Luehmann M, Herzig MC, et al
    Induction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic mice.
    Am J Pathol. 2007;171:2012-20.
    PubMed     Related articles    Abstract available


  7. WILHELMUS MM , Otte-Holler I, van Triel JJ, Veerhuis R, et al
    Lipoprotein receptor-related protein-1 mediates amyloid-beta-mediated cell death of cerebrovascular cells.
    Am J Pathol. 2007;171:1989-99.
    PubMed     Related articles    Abstract available


    August 2007
  8. SPIRES-JONES TL , Meyer-Luehmann M, Osetek JD, Jones PB, et al
    Impaired Spine Stability Underlies Plaque-Related Spine Loss in an Alzheimer's Disease Mouse Model.
    Am J Pathol. 2007;.
    PubMed     Related articles    Abstract available


  9. YANG W , Woltjer RL, Sokal I, Pan C, et al
    Quantitative Proteomics Identifies Surfactant-Resistant {alpha}-Synuclein in Cerebral Cortex of Parkinsonism-Dementia Complex of Guam but Not Alzheimer's Disease or Progressive Supranuclear Palsy.
    Am J Pathol. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  10. CACCAMO A , Oddo S, Tran LX, LaFerla FM, et al
    Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.
    Am J Pathol. 2007;170:1669-75.
    PubMed     Related articles    Abstract available


  11. ZHU X , Avila J, Perry G, Smith MA, et al
    Treating the lesions, not the disease.
    Am J Pathol. 2007;170:1457-9.
    PubMed     Related articles   


    April 2007
  12. ALBRECHT S , Bourdeau M, Bennett D, Mufson EJ, et al
    Activation of caspase-6 in aging and mild cognitive impairment.
    Am J Pathol. 2007;170:1200-9.
    PubMed     Related articles    Abstract available


    March 2007
  13. BODDAERT J , Kinugawa K, Lambert JC, Boukhtouche F, et al
    Evidence of a role for lactadherin in Alzheimer's disease.
    Am J Pathol. 2007;170:921-9.
    PubMed     Related articles    Abstract available


    February 2007
  14. YAMAMOTO M , Kiyota T, Horiba M, Buescher JL, et al
    Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
    Am J Pathol. 2007;170:680-92.
    PubMed     Related articles    Abstract available


    September 2006
  15. PATTON RL , Kalback WM, Esh CL, Kokjohn TA, et al
    Amyloid-{beta} Peptide Remnants in AN-1792-Immunized Alzheimer's Disease Patients: A Biochemical Analysis.
    Am J Pathol. 2006;169:1048-63.
    PubMed     Related articles    Abstract available


  16. LEE HG , Zhu X, Nunomura A, Perry G, et al
    Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!
    Am J Pathol. 2006;169:738-9.
    PubMed     Related articles   


    August 2006
  17. SCHINDOWSKI K , Bretteville A, Leroy K, Begard S, et al
    Alzheimer's Disease-Like Tau Neuropathology Leads to Memory Deficits and Loss of Functional Synapses in a Novel Mutated Tau Transgenic Mouse without Any Motor Deficits.
    Am J Pathol. 2006;169:599-616.
    PubMed     Related articles    Abstract available


    July 2006
  18. PODLESNIY P , Kichev A, Pedraza C, Saurat J, et al
    Pro-NGF from Alzheimer's Disease and Normal Human Brain Displays Distinctive Abilities to Induce Processing and Nuclear Translocation of Intracellular Domain of p75NTR and Apoptosis.
    Am J Pathol. 2006;169:119-31.
    PubMed     Related articles    Abstract available


    May 2006
  19. ANANTHARAMAN M , Tangpong J, Keller JN, Murphy MP, et al
    {beta}-Amyloid Mediated Nitration of Manganese Superoxide Dismutase: Implication for Oxidative Stress in a APPNLh/NLh X PS-1P264L/P264L Double Knock-In Mouse Model of Alzheimer's Disease.
    Am J Pathol. 2006;168:1608-18.
    PubMed     Related articles    Abstract available


    January 2006
  20. ODDO S , Caccamo A, Smith IF, Green KN, et al
    A dynamic relationship between intracellular and extracellular pools of Abeta.
    Am J Pathol. 2006;168:184-94.
    PubMed     Related articles    Abstract available


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