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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Alzheimer's Disease

Free Subscription 30.07.2008 1 BMC Neurol 4 J Biol Chem 1 J Neurochem 4 Lancet 1 Nature 2 Neurochem Res

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Single Articles

BMC Neurol

1. TOBINICK EL , Gross H
   Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer's disease.
   BMC Neurol. 2008;8:27.
   PubMed     Related articles    Abstract available
   
   

   
   J Biol Chem

2. COLE SL , Vassar R
   The role of APP processing by BACE1, the beta-secretase, in Alzheimer's disease pathophysiology.
   J Biol Chem. 2008.
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3. NEET KE , Thinakaran G
   Thematic minireview series on the molecular basis of Alzheimer's disease.
   J Biol Chem. 2008.
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4. SHIMOJO M , Sahara N, Mizoroki T, Funamoto S, et al
   Enzymatic characteristics of I213T mutant presenilin-1/gamma-secretase in cell models and knock-in mouse brains: familial Alzheimer disease-linked mutation impairs gamma-site cleavage of amyloid precursor protein C-terminal fragment beta.
   J Biol Chem. 2008;283:16488-96.
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5. HARTLEY DM , Zhao C, Speier AC, Woodard GA, et al
   Transglutaminase induces protofibril-like amyloid beta-protein assemblies that are protease-resistant and inhibit long-term potentiation.
   J Biol Chem. 2008;283:16790-800.
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   J Neurochem

6. WANG Y , Zhang JX, Du XX, Zhao L, et al
   Temporal correlation of the memory deficit with Alzheimer-like lesions induced by activation of glycogen synthase kinase-3.
   J Neurochem. 2008.
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   Lancet

7. HOLMES C , Boche D, Wilkinson D, Yadegarfar G, et al
   Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial.
   Lancet. 2008;372:216-23.
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8. DOODY RS , Gavrilova SI, Sano M, Thomas RG, et al
   Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study.
   Lancet. 2008;372:207-15.
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9. ST GEORGE-HYSLOP PH , Morris JC
   Will anti-amyloid therapies work for Alzheimer's disease?
   Lancet. 2008;372:180-2.
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10. BURNS A , Jacoby R
    Dimebon in Alzheimer's disease: old drug for new indication.
    Lancet. 2008;372:179-80.
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    Nature

11. HOLTZMAN DM
    Alzheimer's disease: Moving towards a vaccine.
    Nature. 2008;454:418-20.
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    Neurochem Res

12. WANG XC , Zhang YC, Chatterjie N, Grundke-Iqbal I, et al
    Effect of melatonin and melatonylvalpromide on beta-amyloid and neurofilaments in N2a cells.
    Neurochem Res. 2008;33:1138-44.
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13. DUAN RS , Yang X, Chen ZG, Lu MO, et al
    Decreased fractalkine and increased IP-10 expression in aged brain of APP(swe) transgenic mice.
    Neurochem Res. 2008;33:1085-9.
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