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Stem Cell Research

Free Subscription Articles published in J Clin Invest Retrieve available abstracts of 63 articles: HTML format

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May 2024
1. LENARDIC A, Domenig SA, Zvick J, Bundschuh N, et al
   Generation of allogenic and xenogeneic functional muscle stem cells for intramuscular transplantation.
   J Clin Invest. 2024 May 7:e166998. doi: 10.1172/JCI166998.
   PubMed     Abstract available
   
   
   April 2024
2. MOE A, Rayasam A, Sauber G, Shah RK, et al
   Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft versus host disease.
   J Clin Invest. 2024 Apr 25:e175205. doi: 10.1172/JCI175205.
   PubMed     Abstract available
   
   
   
3. KEAN LS, Blazar BR
   Major breakthroughs in hematopoietic stem cell transplantation and future challenges in clinical implementation.
   J Clin Invest. 2024;134:e179944.
   PubMed    
   
   
   
4. NORTH D, Chakraverty R
   The road to refractory graft-versus-host disease is paved with good intentions.
   J Clin Invest. 2024;134:e177728.
   PubMed     Abstract available
   
   
   
5. ZHANG P, Fleming P, Andoniou CE, Waltner OG, et al
   IL-6-mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation.
   J Clin Invest. 2024;134:e174184.
   PubMed     Abstract available
   
   
   March 2024
6. MA H, Lu C, Ziegler J, Liu A, et al
   Absence of Stat1 in donor CD4+ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.
   J Clin Invest. 2024;134:e180350.
   PubMed    
   
   
   
7. ORAVECZ-WILSON K, Lauder E, Taylor A, Maneix L, et al
   Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.
   J Clin Invest. 2024;134:e167369.
   PubMed     Abstract available
   
   
   January 2024
8. LUO M, Bao L, Xue Y, Zhu M, et al
   ZMYND8 protects breast cancer stem cells against oxidative stress and ferroptosis through activation of NRF2.
   J Clin Invest. 2024;134:e171166.
   PubMed     Abstract available
   
   
   
9. SUN YL, Hennessey EE, Heins H, Yang P, et al
   Human pluripotent stem cell modeling of alveolar type 2 cell dysfunction caused by ABCA3 mutations.
   J Clin Invest. 2024;134:e164274.
   PubMed     Abstract available
   
   
   
10. HAIDER N, Kahn CR
    Interactions among insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts.
    J Clin Invest. 2024;134:e172333.
    PubMed     Abstract available
    
    
    
11. SIEW JJ, Chen HM, Chiu FL, Lee CW, et al
    Galectin-3 aggravates microglial activation and tau transmission in tauopathy.
    J Clin Invest. 2024;134:e165523.
    PubMed     Abstract available
    
    
    December 2023
12. MASON EC, Menon S, Schneider BR, Gaskill CF, et al
    Activation of mTOR signaling in adult lung microvascular progenitor cells accelerates lung aging.
    J Clin Invest. 2023;133:e171430.
    PubMed     Abstract available
    
    
    November 2023
13. AVNI B, Neiman D, Shaked ED, Gal-Rosenberg O, et al
    Chronic graft versus host disease detected by tissue-specific cell-free DNA methylation biomarkers.
    J Clin Invest. 2023 Nov 16:e163541. doi: 10.1172/JCI163541.
    PubMed     Abstract available
    
    
    
14. LI M, Nishimura T, Takeuchi Y, Hongu T, et al
    FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters.
    J Clin Invest. 2023;133:e166666.
    PubMed     Abstract available
    
    
    
15. VAZQUEZ-ARMENDARIZ AI, Tata PR
    Recent advances in lung organoid development and applications in disease modeling.
    J Clin Invest. 2023;133:e170500.
    PubMed     Abstract available
    
    
    
16. LOVEWELL RR, Hong J, Kundu S, Fielder CM, et al
    LAIR-1 agonism as a therapy for acute myeloid leukemia.
    J Clin Invest. 2023;133:e169519.
    PubMed     Abstract available
    
    
    October 2023
17. KABRA M, Shahi PK, Wang Y, Sinha D, et al
    Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy.
    J Clin Invest. 2023;133:e171356.
    PubMed     Abstract available
    
    
    August 2023
18. YU C, Sheng Y, Yu F, Ni H, et al
    Foxm1 haploinsufficiency drives clonal hematopoiesis and promotes a stress-related transition to hematologic malignancy in mice.
    J Clin Invest. 2023;133:e163911.
    PubMed     Abstract available
    
    
    
19. LI Q, Wang X, Song Q, Yang S, et al
    Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity.
    J Clin Invest. 2023;133:e165723.
    PubMed     Abstract available
    
    
    
20. BRANDSTADTER JD, Outen R, Maillard I
    Having it both ways: how STAT3 deficiency blocks graft-versus-host disease while preserving graft-versus-leukemia activity.
    J Clin Invest. 2023;133:e172251.
    PubMed     Abstract available
    
    
    
21. LOGAN BR, Fu D, Howard A, Fei M, et al
    Validated graft-specific biomarkers identify patients at risk for chronic graft-versus-host disease and death.
    J Clin Invest. 2023;133:e168575.
    PubMed     Abstract available
    
    
    July 2023
22. SHAH AH, Rivas SR, Doucet-O'Hare TT, Govindarajan V, et al
    Human endogenous retrovirus K contributes to a stem cell niche in glioblastoma.
    J Clin Invest. 2023;133:e167929.
    PubMed     Abstract available
    
    
    June 2023
23. LIN Y, Gu Q, Lu S, Pan Z, et al
    Ruxolitinib improves hematopoietic regeneration by restoring mesenchymal stromal cell function in acute graft-versus-host disease.
    J Clin Invest. 2023 Jun 20:e162201. doi: 10.1172/JCI162201.
    PubMed     Abstract available
    
    
    
24. PASUPULETI SK, Ramdas B, Burns SS, Palam LR, et al
    Obesity-induced inflammation exacerbates clonal hematopoiesis.
    J Clin Invest. 2023;133:e163968.
    PubMed     Abstract available
    
    
    May 2023
25. KERKERING J, Muinjonov B, Rosiewicz KS, Diecke S, et al
    iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
    J Clin Invest. 2023 May 23:e164637. doi: 10.1172/JCI164637.
    PubMed     Abstract available
    
    
    
26. EADE KT, Ansell BRE, Giles S, Fallon R, et al
    iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function.
    J Clin Invest. 2023;133:e163771.
    PubMed     Abstract available
    
    
    February 2023
27. MEERMEIER EW, Bergsagel PL
    Revisiting checkpoint inhibitors for myeloma: maintenance after stem cell transplant.
    J Clin Invest. 2023;133:e167346.
    PubMed     Abstract available
    
    
    
28. WANG YM, Taggart CB, Huber JF, Davies SM, et al
    Daytime-restricted parenteral feeding is associated with earlier oral intake in children following stem cell transplant.
    J Clin Invest. 2023;133:e167275.
    PubMed    
    
    
    January 2023
29. LEE D, Gimple RC, Wu X, Prager BC, et al
    Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.
    J Clin Invest. 2023;133:e163592.
    PubMed     Abstract available
    
    
    December 2022
30. CHOI KM, Kim JJ, Yoo J, Kim KS, et al
    The interferon-inducible protein viperin controls cancer metabolic reprogramming to enhance cancer progression.
    J Clin Invest. 2022;132:e157302.
    PubMed     Abstract available
    
    
    
31. MINNIE SA, Waltner OG, Ensbey KS, Olver SD, et al
    TIGIT inhibition and lenalidomide synergistically promote anti-myeloma immune responses after stem cell transplantation in mice.
    J Clin Invest. 2022 Dec 13:e157907. doi: 10.1172/JCI157907.
    PubMed     Abstract available
    
    
    November 2022
32. LU C, Ma H, Song L, Wang H, et al
    IFNGR/STAT1 signaling in recipient hematopoietic antigen presenting cells suppresses graft-versus-host disease.
    J Clin Invest. 2022 Nov 29:e125986. doi: 10.1172/JCI125986.
    PubMed     Abstract available
    
    
    
33. KUROKAWA K, Wang TC, Hayakawa Y
    R-spondin 3 governs secretory differentiation in the gastric oxyntic glands.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    October 2022
34. YIN N, Jin G, Ma Y, Zhao H, et al
    SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    September 2022
35. SCHUTT S, Wu Y, Kharel A, Bastian D, et al
    The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host disease.
    J Clin Invest. 2022 Sep 8. pii: 143950. doi: 10.1172/JCI143950.
    PubMed     Abstract available
    
    
    August 2022
36. DULMOVITS BM, Olson TS
    Does immune destruction drive all forms of bone marrow failure?
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    July 2022
37. EVANS EJ JR, DeGregori J
    Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
38. JAKUBISON BL, Sarkar T, Gudmundsson KO, Singh S, et al
    ID2 and HIF-1alpha collaborate to protect quiescent hematopoietic stem cells from activation, differentiation, and exhaustion.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    June 2022
39. SELLAR RS, Sperling AS, Slabicki M, Gasser JA, et al
    Degradation of GSPT1 causes TP53-independent cell death in leukemia whilst sparing normal hematopoietic stem cells.
    J Clin Invest. 2022 Jun 28. pii: 153514. doi: 10.1172/JCI153514.
    PubMed     Abstract available
    
    
    
40. FERRARA J, Prado-Acosta M
    Graft-versus-host disease: establishing IL-33 as an important costimulatory molecule.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
41. LIN Q, Wu L, Chatla S, Chowdhury FA, et al
    Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
42. GASPARINI SJ, Tessmer K, Reh M, Wieneke S, et al
    Transplanted human cones incorporate into the retina and function in a murine cone degeneration model.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
43. CASADO JA, Valeri A, Sanchez-Dominguez R, Vela P, et al
    Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia.
    J Clin Invest. 2022 Jun 7. pii: 142842. doi: 10.1172/JCI142842.
    PubMed     Abstract available
    
    
    
44. WICKS EE, Semenza GL
    Hypoxia-inducible factors: cancer progression and clinical translation.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    
45. LIANG J, Huang G, Liu X, Taghavifar F, et al
    The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    May 2022
46. KTENA YP, Koldobskiy MA, Barbato MI, Fu HH, et al
    Donor T-cell DNMT3a regulates alloreactivity in murine models of hematopoietic stem cell transplantation.
    J Clin Invest. 2022 May 24. pii: 158047. doi: 10.1172/JCI158047.
    PubMed     Abstract available
    
    
    
47. DWYER GK, Mathews LR, Villegas JA, Lucas A, et al
    IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease.
    J Clin Invest. 2022 May 3. pii: 150927. doi: 10.1172/JCI150927.
    PubMed     Abstract available
    
    
    February 2022
48. JIANG L, Hao Y, Shao C, Wu Q, et al
    ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance.
    J Clin Invest. 2022 Feb 8. pii: 143397. doi: 10.1172/JCI143397.
    PubMed     Abstract available
    
    
    
49. BUTLER PC, Gale EA
    Reversing type 1 diabetes with stem cell-derived islets: a step closer to the dream?
    J Clin Invest. 2022;132.
    PubMed    
    
    
    
50. SEEBAUER CT, Graus MS, Huang L, McCann A, et al
    Non-beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    January 2022
51. GUAN Y, Hasipek M, Jiang D, Tiwari AD, et al
    Eltrombopag inhibits TET dioxygenase to contribute to hematopoietic stem cell expansion in aplastic anemia.
    J Clin Invest. 2022 Jan 27. pii: 149856. doi: 10.1172/JCI149856.
    PubMed     Abstract available
    
    
    
52. OLIVA AD, Gupta R, Issa K, Abi Hachem R, et al
    Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans.
    J Clin Invest. 2022 Jan 6. pii: 155506. doi: 10.1172/JCI155506.
    PubMed     Abstract available
    
    
    
53. LI Z, Duan H, Jia Y, Zhao C, et al
    Long-term corneal recovery by simultaneous delivery of hPSC-derived corneal endothelial precursors and nicotinamide.
    J Clin Invest. 2022;132.
    PubMed     Abstract available
    
    
    November 2021
54. PERSAUD SP, Ritchey JK, Kim S, Lim S, et al
    Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation.
    J Clin Invest. 2021 Nov 2. pii: 145501. doi: 10.1172/JCI145501.
    PubMed     Abstract available
    
    
    
55. TOKARZ VL, Delgado-Olguin P, Klip A
    Deprogram and reprogram to solve the riddle of insulin resistance.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
56. BRAEUER RR, Walker NM, Misumi K, Mazzoni-Putman S, et al
    Transcription factor FOXF1 identifies compartmentally distinct mesenchymal cells with a role in lung allograft fibrogenesis.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    October 2021
57. CHEN Z, Lu T, Huang L, Wang Z, et al
    Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    August 2021
58. QIAN J, LeSavage BL, Hubka KM, Ma C, et al
    Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    June 2021
59. TANG XY, Xu L, Wang J, Hong Y, et al
    DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
60. LOONG JH, Wong TL, Tong M, Sharma R, et al
    Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    April 2021
61. WANG L, Liu Y, Stratigopoulos G, Panigrahi S, et al
    Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    March 2021
62. MUSCARELLA AM, Aguirre S, Hao X, Waldvogel SM, et al
    Exploiting bone niches: progression of disseminated tumor cells to metastasis.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    
    
63. OSUKA S, Zhu D, Zhang Z, Li C, et al
    N-cadherin upregulation mediates adaptive radioresistance in glioblastoma.
    J Clin Invest. 2021;131.
    PubMed     Abstract available
    
    

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