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  Neoplasms of the CNS

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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 39 articles:
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Single Articles


    May 2024
  1. ASHOKAN A, Sarkar S, Kamran MZ, Surnar B, et al
    Simultaneous targeting of peripheral and brain tumors with a therapeutic nanoparticle to disrupt metabolic adaptability at both sites.
    Proc Natl Acad Sci U S A. 2024;121:e2318119121.
    PubMed     Abstract available


  2. GOYETTE MA, Stevens LE, DePinho CR, Seehawer M, et al
    Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
    Proc Natl Acad Sci U S A. 2024;121:e2322688121.
    PubMed     Abstract available


    April 2024
  3. WU R, Sun C, Chen X, Yang R, et al
    NSUN5/TET2-directed chromatin-associated RNA modification of 5-methylcytosine to 5-hydroxymethylcytosine governs glioma immune evasion.
    Proc Natl Acad Sci U S A. 2024;121:e2321611121.
    PubMed     Abstract available


    March 2024
  4. SAITO Y, Yang Y, Saito M, Park CY, et al
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells.
    Proc Natl Acad Sci U S A. 2024;121:e2314695121.
    PubMed     Abstract available


    February 2024
  5. WANG R, Lei H, Wang H, Qi L, et al
    Dysregulated inter-mitochondrial crosstalk in glioblastoma cells revealed by in situ cryo-electron tomography.
    Proc Natl Acad Sci U S A. 2024;121:e2311160121.
    PubMed     Abstract available


  6. NOCH EK, Palma L, Yim I, Bullen N, et al
    Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production.
    Proc Natl Acad Sci U S A. 2024;121:e2317343121.
    PubMed     Abstract available


  7. KUDRUK S, Forsyth CM, Dion MZ, Hedlund Orbeck JK, et al
    Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy.
    Proc Natl Acad Sci U S A. 2024;121:e2306973121.
    PubMed     Abstract available


    December 2023
  8. WEN J, Nasrallah IM, Abdulkadir A, Satterthwaite TD, et al
    Genomic loci influence patterns of structural covariance in the human brain.
    Proc Natl Acad Sci U S A. 2023;120:e2300842120.
    PubMed     Abstract available


    September 2023
  9. PANT A, Lim M
    Overcoming EGFR inhibitor resistance in Glioblastoma by targeting co-amplified genes.
    Proc Natl Acad Sci U S A. 2023;120:e2312277120.
    PubMed    


    August 2023
  10. ROY A, Sakthikumar S, Kozyrev SV, Nordin J, et al
    Using evolutionary constraint to define novel candidate driver genes in medulloblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2300984120.
    PubMed     Abstract available


  11. VOUTYRAKI C, Choromidis A, Meligkounaki A, Vlachopoulos NA, et al
    Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model.
    Proc Natl Acad Sci U S A. 2023;120:e2221601120.
    PubMed     Abstract available


  12. ZENG K, Zeng Y, Zhan H, Zhan Z, et al
    SEC61G assists EGFR-amplified glioblastoma to evade immune elimination.
    Proc Natl Acad Sci U S A. 2023;120:e2303400120.
    PubMed     Abstract available


    May 2023
  13. RAVIRAM R, Raman A, Preissl S, Ning J, et al
    Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity.
    Proc Natl Acad Sci U S A. 2023;120:e2210991120.
    PubMed     Abstract available


  14. WANG F, Huang Q, Su H, Sun M, et al
    Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2204621120.
    PubMed     Abstract available


  15. MOTA M, Sweha SR, Pun M, Natarajan SK, et al
    Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas.
    Proc Natl Acad Sci U S A. 2023;120:e2221175120.
    PubMed     Abstract available


    April 2023
  16. MISHRA-GORUR K, Barak T, Kaulen LD, Henegariu O, et al
    Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.
    Proc Natl Acad Sci U S A. 2023;120:e2214997120.
    PubMed     Abstract available


  17. CHIPMAN ME, Wang Z, Sun D, Pedraza AM, et al
    Tumor progression is independent of tumor-associated macrophages in cell lineage-based mouse models of glioblastoma.
    Proc Natl Acad Sci U S A. 2023;120:e2222084120.
    PubMed     Abstract available


    February 2023
  18. BASSEY-ARCHIBONG BI, Rajendra Chokshi C, Aghaei N, Kieliszek AM, et al
    An HLA-G/SPAG9/STAT3 axis promotes brain metastases.
    Proc Natl Acad Sci U S A. 2023;120:e2205247120.
    PubMed     Abstract available


  19. DATTA M, Chatterjee S, Perez EM, Gritsch S, et al
    Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models.
    Proc Natl Acad Sci U S A. 2023;120:e2219199120.
    PubMed     Abstract available


    September 2022
  20. PENG KL, Vasudevan HN, Lockney DT, Baum R, et al
    Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance.
    Proc Natl Acad Sci U S A. 2022;119:e2203738119.
    PubMed     Abstract available


    August 2022
  21. MITSDOERFFER M, Aly L, Barz M, Engleitner T, et al
    The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans.
    Proc Natl Acad Sci U S A. 2022;119:e2206208119.
    PubMed     Abstract available


  22. CHEN L, Li Y, Song Z, Xue S, et al
    O-GlcNAcylation promotes cerebellum development and medulloblastoma oncogenesis via SHH signaling.
    Proc Natl Acad Sci U S A. 2022;119:e2202821119.
    PubMed     Abstract available


  23. PERRYMAN R, Renziehausen A, Shaye H, Kostagianni AD, et al
    Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma.
    Proc Natl Acad Sci U S A. 2022;119:e2116289119.
    PubMed     Abstract available


    July 2022
  24. SARDAR D, Chen HC, Reyes A, Varadharajan S, et al
    Sox9 directs divergent epigenomic states in brain tumor subtypes.
    Proc Natl Acad Sci U S A. 2022;119:e2202015119.
    PubMed     Abstract available


  25. BERGER G, Knelson EH, Jimenez-Macias JL, Nowicki MO, et al
    STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models.
    Proc Natl Acad Sci U S A. 2022;119:e2111003119.
    PubMed     Abstract available


    June 2022
  26. STRAEHLA JP, Hajal C, Safford HC, Offeddu GS, et al
    A predictive microfluidic model of human glioblastoma to assess trafficking of blood-brain barrier-penetrant nanoparticles.
    Proc Natl Acad Sci U S A. 2022;119:e2118697119.
    PubMed     Abstract available


    May 2022
  27. LIU W, Sun P, Xia L, He X, et al
    A brain-enriched lncRNA shields cancer cells from immune-mediated killing for metastatic colonization in the brain.
    Proc Natl Acad Sci U S A. 2022;119:e2200230119.
    PubMed     Abstract available


    March 2022
  28. GOVERNA V, Talbot H, Goncalves de Oliveira K, Cerezo-Magana M, et al
    Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


  29. MILANO L, Charlier CF, Andreguetti R, Cox T, et al
    A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    January 2022
  30. CORDERO A, Ramsey MD, Kanojia D, Fares J, et al
    Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer.
    Proc Natl Acad Sci U S A. 2022;119.
    PubMed     Abstract available


    November 2021
  31. AABEDI AA, Lipkin B, Kaur J, Kakaizada S, et al
    Functional alterations in cortical processing of speech in glioma-infiltrated cortex.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  32. WANG J, Toregrosa-Allen S, Elzey BD, Utturkar S, et al
    Multispecific targeting of glioblastoma with tumor microenvironment-responsive multifunctional engineered NK cells.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    September 2021
  33. ANASTASIADIS P, Gandhi D, Guo Y, Ahmed AK, et al
    Localized blood-brain barrier opening in infiltrating gliomas with MRI-guided acoustic emissions-controlled focused ultrasound.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    May 2021
  34. BURKS SR, Kersch CN, Witko JA, Pagel MA, et al
    Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    April 2021
  35. LI J, Kaneda MM, Ma J, Li M, et al
    PI3Kgamma inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


  36. KFOURY N, Qi Z, Prager BC, Wilkinson MN, et al
    Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    March 2021
  37. AMEN AM, Fellmann C, Soczek KM, Ren SM, et al
    Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    February 2021
  38. MONCHO-AMOR V, Chakravarty P, Galichet C, Matheu A, et al
    SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed     Abstract available


    December 2020
  39. HOJ JP, Mayro B, Pendergast AM
    The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis.
    Proc Natl Acad Sci U S A. 2020 Dec 14. pii: 2007991117.
    PubMed     Abstract available


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